Detailed information for compound 2076500

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 455.494 | Formula: C21H24F3N3O3S
  • H donors: 1 H acceptors: 4 LogP: 0.88 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: OC(=O)C(F)(F)F.O=C1CCC2(N1Cc1ccccc1)CCN(CC2)Cc1nccs1
  • InChi: 1S/C19H23N3OS.C2HF3O2/c23-18-6-7-19(22(18)14-16-4-2-1-3-5-16)8-11-21(12-9-19)15-17-20-10-13-24-17;3-2(4,5)1(6)7/h1-5,10,13H,6-9,11-12,14-15H2;(H,6,7)
  • InChiKey: VQBPVHFHIMUGSG-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus Nuclear hormone receptor HR96 0.0016 0.0061 0.0064
Echinococcus granulosus protein tyrosine phosphatase n9 0.0013 0.0018 0.0019
Echinococcus granulosus inositol monophosphatase 1 0.002 0.0129 0.0135
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0043 0.055 0.1047
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0016 0.0061 0.0142
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0013 0.0018 0.002
Brugia malayi Protein-tyrosine phosphatase 0.0013 0.0018 0.002
Loa Loa (eye worm) hypothetical protein 0.0013 0.0018 0.002
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0013 0.0018 0.0019
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0013 0.0018 0.0019
Onchocerca volvulus 0.0034 0.0376 0.118
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0013 0.0018 0.002
Echinococcus multilocularis lysine specific demethylase 5A 0.006 0.0846 0.0846
Loa Loa (eye worm) hypothetical protein 0.0016 0.0061 0.0067
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0013 0.0018 0.002
Echinococcus granulosus geminin 0.0294 0.4987 0.5225
Echinococcus multilocularis dual specificity 0.0064 0.0905 0.0905
Schistosoma mansoni tar DNA-binding protein 0.0101 0.1565 0.1707
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0108 0.2211
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0108 0.2211
Loa Loa (eye worm) hypothetical protein 0.0018 0.0095 0.0104
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0108 0.2211
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0101 0.1565 0.1707
Schistosoma mansoni protein tyrosine phosphatase non-receptor type nt1 0.053 0.9166 1
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.002 0.0129 0.0245
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0019 0.0108 0.0206
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0064 0.0905 0.1722
Loa Loa (eye worm) hypothetical protein 0.0013 0.0018 0.002
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0043 0.055 0.1047
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0013 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0013 0.0018 0.002
Schistosoma mansoni protein-tyrosine phosphatase n9 0.0013 0.0018 0.002
Loa Loa (eye worm) hypothetical protein 0.0013 0.0018 0.002
Loa Loa (eye worm) hypothetical protein 0.0016 0.0061 0.0067
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0016 0.0061 0.0067
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0121 1
Entamoeba histolytica hypothetical protein 0.0046 0.0598 0.6543
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0013 0.0018 0.002
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0034 0.0376 0.0394
Loa Loa (eye worm) hypothetical protein 0.0013 0.0018 0.002
Trypanosoma cruzi tyrosine specific protein phosphatase, putative 0.0013 0.0018 0.0035
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0064 0.0905 0.0987
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0034 0.0376 0.041
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0013 0.0018 0.0019
Loa Loa (eye worm) hypothetical protein 0.0034 0.0376 0.041
Brugia malayi latrophilin 2 splice variant baaae 0.0024 0.021 0.0229
Entamoeba histolytica hypothetical protein 0.0064 0.0905 1
Entamoeba histolytica protein kinase, putative 0.0064 0.0905 1
Schistosoma mansoni phd/f-box containing protein 0.0016 0.0064 0.007
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0034 0.0376 0.0376
Loa Loa (eye worm) hypothetical protein 0.0013 0.0018 0.002
Loa Loa (eye worm) DR-78 0.0016 0.0061 0.0067
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0036 0.0425 0.0463
Loa Loa (eye worm) hypothetical protein 0.0016 0.0061 0.0067
Brugia malayi Nuclear hormone receptor E75 0.0016 0.0061 0.0067
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0309 0.5254 1
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0013 0.0018 0.0018
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0013 0.0018 0.002
Brugia malayi hypothetical protein 0.0046 0.0598 0.0653
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0019 0.0108 0.0206
Loa Loa (eye worm) hypothetical protein 0.0013 0.0018 0.002
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0034 0.0376 0.0376
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0108 0.2211
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0121 0.0127
Schistosoma mansoni receptor protein tyrosine phosphatase r (pcptp1) 0.0013 0.0018 0.002
Brugia malayi jmjC domain containing protein 0.006 0.0846 0.0923
Loa Loa (eye worm) inositol-1 0.002 0.0129 0.014
Schistosoma mansoni hypothetical protein 0.0024 0.021 0.0229
Loa Loa (eye worm) hypothetical protein 0.0016 0.0061 0.0067
Echinococcus granulosus serine protein kinase ATM 0.0025 0.023 0.0241
Echinococcus multilocularis serine protein kinase ATM 0.0025 0.023 0.023
Echinococcus multilocularis receptor type tyrosine protein phosphatase H 0.0013 0.0018 0.0018
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0016 0.0064 0.0864
Brugia malayi ecdysone receptor 0.0016 0.0061 0.0067
Loa Loa (eye worm) hypothetical protein 0.0013 0.0018 0.002
Mycobacterium tuberculosis Conserved hypothetical protein 0.0163 0.2664 1
Trypanosoma brucei protein tyrosine phosphatase 1 0.0013 0.0018 0.0035
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0013 0.0018 0.002
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0013 0.0018 0.0018
Schistosoma mansoni inositol monophosphatase 0.002 0.0129 0.014
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0043 0.055 0.1047
Schistosoma mansoni cellular tumor antigen P53 0.0026 0.0247 0.0269
Brugia malayi jmjC domain containing protein 0.0016 0.0064 0.007
Echinococcus granulosus phd:f box containing protein 0.0016 0.0064 0.0068
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0019 0.0121 0.1161
Loa Loa (eye worm) hypothetical protein 0.0013 0.0018 0.002
Brugia malayi jmjC domain containing protein 0.006 0.0846 0.0923
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0034 0.0376 0.0394
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0025 0.023 0.0251
Echinococcus multilocularis receptor type tyrosine protein phosphatase protein tyrosine phosphatase receptor type 0.0013 0.0018 0.0018
Brugia malayi nuclear receptor RXR 0.0016 0.0061 0.0067
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0034 0.0376 0.041
Schistosoma mansoni receptor protein tyrosine phosphatase 0.0013 0.0018 0.002
Mycobacterium ulcerans hypothetical protein 0.0163 0.2664 1
Schistosoma mansoni hypothetical protein 0.0046 0.0598 0.0653
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0019 0.0108 0.0113
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0019 0.0108 0.1013
Echinococcus multilocularis lysine specific demethylase 6a 0.0016 0.0064 0.0064
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0019 0.0108 0.0206
Brugia malayi nuclear hormone receptor 0.0034 0.0376 0.041
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0013 0.0018 0.002
Loa Loa (eye worm) protein-tyrosine phosphatase 1 0.0013 0.0018 0.002
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0019 0.0108 0.0206
Loa Loa (eye worm) hypothetical protein 0.0013 0.0018 0.002
Loa Loa (eye worm) hypothetical protein 0.0013 0.0018 0.002
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0013 0.0018 0.002
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0108 0.2211
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0013 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0016 0.0061 0.0067
Entamoeba histolytica hypothetical protein 0.0046 0.0598 0.6543
Mycobacterium leprae cell division protein FtsZ 0.0098 0.1521 1
Loa Loa (eye worm) hypothetical protein 0.0013 0.0018 0.002
Loa Loa (eye worm) hypothetical protein 0.0018 0.0095 0.0104
Echinococcus multilocularis FTZ F1 alpha 0.0034 0.0376 0.0376
Schistosoma mansoni nuclear receptor 0.0016 0.0061 0.0067
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0013 0.0018 0.002
Schistosoma mansoni pcd6 interacting protein-related 0.0013 0.0018 0.002
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0019 0.0121 0.0455
Brugia malayi Calcitonin receptor-like protein seb-1 0.0035 0.0408 0.0446
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.002 0.0129 0.0054
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0016 0.0061 0.0067
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0013 0.0018 0.002
Brugia malayi ecdysteroid receptor 0.0034 0.0376 0.041
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0108 0.2211
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0035 0.0408 0.0446
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.002 0.0129 0.0483
Loa Loa (eye worm) hypothetical protein 0.0013 0.0018 0.002
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0034 0.0376 0.041
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0108 0.2211
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0019 0.0108 0.0118
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0034 0.0376 0.041
Loa Loa (eye worm) hypothetical protein 0.0022 0.0167 0.0183
Echinococcus granulosus lysine specific demethylase 6a 0.0016 0.0064 0.0068
Loa Loa (eye worm) hypothetical protein 0.0034 0.0376 0.041
Loa Loa (eye worm) fibronectin type III domain-containing protein 0.0013 0.0018 0.002
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0121 0.023
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0034 0.0376 0.0376
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0067 0.0968 0.0968
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0019 0.0108 0.0206
Loa Loa (eye worm) hypothetical protein 0.0013 0.0018 0.002
Loa Loa (eye worm) hypothetical protein 0.0016 0.0061 0.0067
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0013 0.0018 0.0018
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0034 0.0376 0.0376
Echinococcus multilocularis receptor type tyrosine protein phosphatase zeta 0.0013 0.0018 0.0018
Trichomonas vaginalis myo inositol monophosphatase, putative 0.002 0.0129 0.2719
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0043 0.055 0.1047
Brugia malayi RNA binding protein 0.0101 0.1565 0.1707
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0013 0.0018 0.0018
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0034 0.0376 0.041
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0121 0.0132
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0034 0.0376 0.041
Brugia malayi nuclear hormone receptor family member odr-7 0.0016 0.0061 0.0067
Brugia malayi jmjC domain containing protein 0.0016 0.0064 0.007
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0064 0.007
Echinococcus granulosus thyroid hormone receptor alpha 0.0016 0.0061 0.0064
Brugia malayi Nuclear hormone receptor E75 0.0016 0.0061 0.0067
Brugia malayi Melibiase family protein 0.0036 0.0425 0.0463
Brugia malayi hypothetical protein 0.0013 0.0018 0.002
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0019 0.0108 0.0206
Brugia malayi hypothetical protein 0.0013 0.0018 0.002
Trichomonas vaginalis myo inositol monophosphatase, putative 0.002 0.0129 0.2719
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0064 0.007
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0018 0.0095 0.0104
Echinococcus multilocularis ecdysone induced protein 78C 0.0034 0.0376 0.0376
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0034 0.0376 0.041
Loa Loa (eye worm) hypothetical protein 0.0013 0.0018 0.002
Loa Loa (eye worm) TAR-binding protein 0.0101 0.1565 0.1707
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0013 0.0018 0.0018
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0034 0.0376 0.041
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0121 0.0455
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0013 0.0018 0.002
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0016 0.0061 0.0061
Onchocerca volvulus 0.0026 0.0247 0.0754
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0016 0.0061 0.0061
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0022 0.0167 0.0319
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0013 0.0018 0.002
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0019 0.0108 0.0118
Brugia malayi protein-tyrosine phosphatase Lar-like precursor, putative 0.0013 0.0018 0.002
Loa Loa (eye worm) protein tyrosine phosphatase 0.0013 0.0018 0.002
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0108 0.2211
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0013 0.0018 0.002
Echinococcus multilocularis jumonji domain containing 1A 0.0016 0.0064 0.0064
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0013 0.0018 0.002
Loa Loa (eye worm) hypothetical protein 0.0024 0.021 0.0229
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0013 0.0018 0.0019
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0034 0.0376 0.0376
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0013 0.0018 0.002
Onchocerca volvulus 0.0016 0.0061 0.0142
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0019 0.0108 0.1013
Trichomonas vaginalis inositol monophosphatase, putative 0.002 0.0129 0.2719
Loa Loa (eye worm) hypothetical protein 0.0013 0.0018 0.002
Brugia malayi nuclear receptor RXR 0.0018 0.0095 0.0104
Schistosoma mansoni protein phosphatase 2C 0.0016 0.0064 0.007
Brugia malayi Nuclear hormone receptor-like 1 0.0018 0.0095 0.0104
Loa Loa (eye worm) hypothetical protein 0.0018 0.0095 0.0104
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0108 0.2211
Echinococcus granulosus Receptor type tyrosine protein phosphatase O 0.0013 0.0018 0.0019
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0018 0.0095 0.0104
Brugia malayi Cell division protein ftsZ 0.0049 0.0639 0.0698
Brugia malayi jmjC domain containing protein 0.0016 0.0064 0.007
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0013 0.0018 0.002
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0064 0.0905 0.1722
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0013 0.0018 0.0019
Loa Loa (eye worm) hypothetical protein 0.0016 0.0061 0.0067
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0121 1
Schistosoma mansoni tar DNA-binding protein 0.0101 0.1565 0.1707
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0064 0.0905 0.1722
Echinococcus multilocularis receptor type tyrosine protein phosphatase zeta 0.0013 0.0018 0.0018
Brugia malayi Nuclear hormone receptor-like 1 0.0034 0.0376 0.041
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0019 0.0108 0.0108
Echinococcus granulosus receptor type tyrosine protein phosphatase zeta 0.0013 0.0018 0.0019
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0055 0.0747 0.0814
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0034 0.0376 0.041
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0019 0.0108 0.0206
Schistosoma mansoni tar DNA-binding protein 0.0101 0.1565 0.1707
Trichomonas vaginalis alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative 0.0036 0.0425 1
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0034 0.0376 0.041
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0108 0.2211
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0121 0.2533
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0019 0.0108 0.0206
Echinococcus granulosus lysine specific demethylase 5A 0.006 0.0846 0.0887
Schistosoma mansoni jumonji domain containing protein 0.0016 0.0064 0.007
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0013 0.0018 0.002
Loa Loa (eye worm) hypothetical protein 0.0034 0.0376 0.041
Entamoeba histolytica protein kinase domain containing protein 0.0064 0.0905 1
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0034 0.0376 0.0394
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0108 0.2211
Schistosoma mansoni receptor protein tyrosine phosphatase n (ia2) 0.0013 0.0018 0.002
Onchocerca volvulus Bile acid receptor homolog 0.0034 0.0376 0.118
Loa Loa (eye worm) hypothetical protein 0.0016 0.0061 0.0067
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0013 0.0018 0.002
Mycobacterium tuberculosis Cell division protein FtsZ 0.0098 0.1521 0.5711
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0013 0.0018 0.002
Brugia malayi Dual specificity protein phosphatase CDC14B 0.0013 0.0018 0.002
Schistosoma mansoni tar DNA-binding protein 0.0101 0.1565 0.1707
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0019 0.0108 0.0113
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0108 0.2211
Brugia malayi hypothetical protein 0.0013 0.0018 0.002
Echinococcus granulosus FTZ F1 alpha 0.0034 0.0376 0.0394
Brugia malayi hypothetical protein 0.0013 0.0018 0.002
Schistosoma mansoni jumonji/arid domain-containing protein 0.006 0.0846 0.0923
Toxoplasma gondii melibiase subfamily protein 0.0055 0.0747 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0034 0.0376 0.041
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0013 0.0018 0.002
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0108 0.2211
Loa Loa (eye worm) nuclear hormone receptor 0.0016 0.0061 0.0067
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0016 0.0061 0.0064
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0108 0.2211
Echinococcus multilocularis phd:f box containing protein 0.0016 0.0064 0.0064
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0034 0.0376 0.041
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0025 0.023 0.0439
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0018 0.0092 0.0346
Onchocerca volvulus 0.0016 0.0061 0.0142
Brugia malayi TAR-binding protein 0.0101 0.1565 0.1707
Echinococcus granulosus tumor protein p63 0.018 0.2968 0.3109
Schistosoma mansoni ap endonuclease 0.0019 0.0121 0.0132
Loa Loa (eye worm) hypothetical protein 0.0034 0.0376 0.041
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0013 0.0018 0.0019
Entamoeba histolytica myo-inositol monophosphatase, putative 0.002 0.0129 0.1246
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0034 0.0376 0.041
Brugia malayi Inositol-1 0.002 0.0129 0.014
Schistosoma mansoni protein tyrosine phosphatase 0.0013 0.0018 0.002
Schistosoma mansoni ap endonuclease 0.0019 0.0121 0.0132
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0034 0.0376 0.0394
Echinococcus multilocularis receptor type tyrosine protein phosphatase protein tyrosine phosphatase receptor type 0.0013 0.0018 0.0018
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0309 0.5254 1
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0034 0.0376 0.041
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0016 0.0061 0.0061
Schistosoma mansoni zinc finger protein 0.0016 0.0061 0.0067
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0013 0.0018 0.002
Loa Loa (eye worm) hypothetical protein 0.0013 0.0018 0.002
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0013 0.0018 0.002
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0013 0.0018 0.002
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0013 0.0018 0.002
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0018 0.0095 0.0104
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0019 0.0108 0.0206
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0016 0.0064 0.0123
Schistosoma mansoni phosphatidylserine receptor 0.0016 0.0064 0.007
Leishmania major hypothetical protein, conserved 0.0016 0.0064 0.0123
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0016 0.0061 0.0067
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0013 0.0018 0.002
Brugia malayi orphan nuclear receptor NR2E1 0.0016 0.0061 0.0067
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.006 0.0846 0.0887
Loa Loa (eye worm) hypothetical protein 0.0034 0.0376 0.041
Schistosoma mansoni transcription factor LCR-F1 0.0046 0.0598 0.0653
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0046 0.0598 0.0627
Schistosoma mansoni nuclear hormone receptor 0.0034 0.0376 0.041
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0013 0.0018 0.0019
Leishmania major phosphatidylinositol kinase related protein, putative 0.0019 0.0109 0.0207
Echinococcus granulosus Receptor type tyrosine protein phosphatase O 0.0013 0.0018 0.0019
Loa Loa (eye worm) hypothetical protein 0.0016 0.0064 0.007
Mycobacterium ulcerans cell division protein FtsZ 0.0098 0.1521 0.5711
Brugia malayi RNA recognition motif domain containing protein 0.0101 0.1565 0.1707
Echinococcus multilocularis 0.0013 0.0018 0.0018
Brugia malayi tailless protein 0.0016 0.0061 0.0067
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0016 0.0064 0.0123
Echinococcus multilocularis nuclear receptor nhr 48 0.0016 0.0061 0.0061
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0016 0.0061 0.0067
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0016 0.0061 0.0064
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0019 0.0108 0.0118
Giardia lamblia GTOR 0.0019 0.0108 0.8729
Brugia malayi hypothetical protein 0.0013 0.0018 0.002
Loa Loa (eye worm) hypothetical protein 0.0013 0.0018 0.002
Echinococcus multilocularis inositol monophosphatase 1 0.002 0.0129 0.0129
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0019 0.0108 0.0118
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0013 0.0018 0.002
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0019 0.0108 0.0206
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0013 0.0018 0.002
Schistosoma mansoni steroid hormone receptor ad4bp 0.0034 0.0376 0.041
Loa Loa (eye worm) hypothetical protein 0.0036 0.0425 0.0463
Loa Loa (eye worm) hypothetical protein 0.0016 0.0061 0.0067
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0018 0.0092 0.0606
Brugia malayi nuclear hormone receptor 0.0016 0.0061 0.0067
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0016 0.0061 0.0061
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0034 0.0376 0.041
Echinococcus multilocularis tumor protein p63 0.018 0.2968 0.2968
Loa Loa (eye worm) hypothetical protein 0.0013 0.0018 0.002
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0108 0.2211
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0185 0.3052 1
Loa Loa (eye worm) hypothetical protein 0.0013 0.0018 0.002
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0013 0.0018 0.0018
Schistosoma mansoni hypothetical protein 0.0067 0.0968 0.1056
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0108 0.2211
Echinococcus multilocularis hypothetical protein 0.0013 0.0018 0.0018
Loa Loa (eye worm) dual specificity protein phosphatase CDC14B 0.0013 0.0018 0.002
Brugia malayi hypothetical protein 0.0018 0.0095 0.0104
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0013 0.0018 0.0018
Echinococcus multilocularis geminin 0.0294 0.4987 0.4987
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0121 0.023
Brugia malayi nuclear receptor NHR-88 0.0016 0.0061 0.0067
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0025 0.023 0.0439
Loa Loa (eye worm) phosphatidylinositol 3 0.0019 0.0108 0.0118
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0121 0.0132
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0019 0.0121 1
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0013 0.0018 0.0019
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0013 0.0018 0.002
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.006 0.0846 0.0846
Brugia malayi Protein-tyrosine phosphatase containing protein 0.053 0.9166 1
Brugia malayi Protein kinase domain containing protein 0.0064 0.0905 0.0987
Brugia malayi conserved hypotetical protein 0.0016 0.0061 0.0067
Schistosoma mansoni non-receptor protein-tyrosine phosphatase 0.0013 0.0018 0.002
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0108 0.2211
Toxoplasma gondii FATC domain-containing protein 0.0025 0.023 0.3087
Loa Loa (eye worm) RNA binding protein 0.0101 0.1565 0.1707
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0108 0.2211
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0019 0.0109 0.0207
Brugia malayi hypothetical protein 0.0018 0.0095 0.0104
Schistosoma mansoni RAR-like nuclear receptor 0.0034 0.0376 0.041
Loa Loa (eye worm) hypothetical protein 0.0016 0.0061 0.0067
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0034 0.0376 0.0376
Echinococcus granulosus nuclear receptor nhr 48 0.0016 0.0061 0.0064
Loa Loa (eye worm) hypothetical protein 0.0035 0.0408 0.0446
Echinococcus multilocularis tar DNA binding protein 0.0101 0.1565 0.1565
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0309 0.5254 1
Loa Loa (eye worm) hypothetical protein 0.0185 0.3052 0.333
Entamoeba histolytica hypothetical protein 0.0046 0.0598 0.6543
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0046 0.0598 0.0598
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0013 0.0018 0.002
Brugia malayi photoreceptor-specific nuclear receptor 0.0034 0.0376 0.041
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0055 0.0747 0.0814
Schistosoma mansoni jumonji/arid domain-containing protein 0.006 0.0846 0.0923
Wolbachia endosymbiont of Brugia malayi cell division protein FtsZ 0.0098 0.1521 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0108 0.2211
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0108 0.2211
Loa Loa (eye worm) hypothetical protein 0.0063 0.0899 0.0981
Loa Loa (eye worm) hypothetical protein 0.0018 0.0095 0.0104
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0034 0.0376 0.0394
Echinococcus granulosus receptor type tyrosine protein phosphatase zeta 0.0013 0.0018 0.0019
Brugia malayi nuclear receptor NHR-67 0.0016 0.0061 0.0067
Leishmania major phosphatidylinositol 3-kinase, putative 0.0019 0.0108 0.0206
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0034 0.0376 0.041
Loa Loa (eye worm) hypothetical protein 0.0026 0.0247 0.0269
Loa Loa (eye worm) hypothetical protein 0.0013 0.0018 0.002
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0034 0.0376 0.041
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0108 0.2211
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0121 0.0121
Leishmania major mitochondrial DNA polymerase beta 0.0309 0.5254 1
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0013 0.0018 0.002
Loa Loa (eye worm) hypothetical protein 0.0016 0.0064 0.007
Echinococcus multilocularis thyroid hormone receptor alpha 0.0101 0.1564 0.1564
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0019 0.0108 0.0206
Echinococcus granulosus ecdysone induced protein 78C 0.0034 0.0376 0.0394
Echinococcus multilocularis protein tyrosine phosphatase n9 0.0013 0.0018 0.0018
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.002 0.0129 0.1724
Loa Loa (eye worm) protein-tyrosine-phosphatase 0.0013 0.0018 0.002
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0108 0.2211
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0108 0.2211
Loa Loa (eye worm) hypothetical protein 0.0013 0.0018 0.002
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0146 0.2371 0.4512
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0108 0.2211
Brugia malayi steroid hormone receptor 0.0034 0.0376 0.041
Toxoplasma gondii exonuclease III APE 0.0019 0.0121 0.1622
Loa Loa (eye worm) hypothetical protein 0.0016 0.0061 0.0067
Brugia malayi hypothetical protein 0.0016 0.0061 0.0067
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0019 0.0108 0.0206
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0016 0.0064 0.0068
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0034 0.0376 0.041
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.023 0.5223
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0013 0.0018 0.002
Echinococcus granulosus Alpha N acetylgalactosaminidase 0.0055 0.0747 0.0782
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0013 0.0018 0.0019
Echinococcus granulosus Solute carrier family 22 5 0.0552 0.9546 1
Echinococcus granulosus jumonji domain containing 1A 0.0016 0.0064 0.0068
Brugia malayi nuclear hormone receptor family member nhr-6 0.0016 0.0061 0.0067
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0067 0.0968 0.1014
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0034 0.0376 0.041
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0013 0.0018 0.002
Echinococcus multilocularis JmjC domain containing protein 4 0.0016 0.0064 0.0064
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0013 0.0018 0.0018
Schistosoma mansoni nuclear hormone receptor 0.0016 0.0061 0.0067
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0016 0.0064 0.0123
Loa Loa (eye worm) hypothetical protein 0.0013 0.0018 0.002
Loa Loa (eye worm) steroid hormone receptor 0.0034 0.0376 0.041
Schistosoma mansoni receptor protein tyrosine phosphatase n (ia2) 0.0013 0.0018 0.002
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0013 0.0018 0.002
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.0013 0.0018 0.002
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0034 0.0376 0.041
Loa Loa (eye worm) hypothetical protein 0.0063 0.0899 0.0981
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0034 0.0376 0.0394
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0064 0.0905 0.1722
Schistosoma mansoni protein-tyrosine phosphatase non-receptor type nt5 0.0013 0.0018 0.002
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0013 0.0018 0.002
Schistosoma mansoni hypothetical protein 0.0294 0.4987 0.5441
Loa Loa (eye worm) hypothetical protein 0.0034 0.0376 0.041
Loa Loa (eye worm) hypothetical protein 0.0013 0.0018 0.002
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0121 0.023
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0013 0.0018 0.0018
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0016 0.0064 0.0864
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0108 0.2211
Leishmania major protein-tyrosine phosphatase 1-like protein 0.0013 0.0018 0.0035
Echinococcus multilocularis Glycoside hydrolase, family 27 0.0055 0.0747 0.0747
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.053 0.9166 0.9166
Schistosoma mansoni protein tyrosine phosphatase 0.0013 0.0018 0.002
Loa Loa (eye worm) hypothetical protein 0.0013 0.0018 0.002
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0013 0.0018 0.002
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0034 0.0376 0.041
Loa Loa (eye worm) hypothetical protein 0.0016 0.0061 0.0067
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0064 0.007
Loa Loa (eye worm) hypothetical protein 0.0034 0.0376 0.041
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0034 0.0376 0.041
Echinococcus multilocularis Alpha N acetylgalactosaminidase 0.0055 0.0747 0.0747
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0035 0.0408 0.0446
Loa Loa (eye worm) phosphatidylinositol 3 0.0019 0.0108 0.0118
Brugia malayi Nuclear hormone receptor-like 1 0.0018 0.0095 0.0104
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0025 0.023 0.0251
Entamoeba histolytica hypothetical protein 0.0025 0.023 0.2394
Schistosoma mansoni coup transcription factor 0.0034 0.0376 0.041
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0121 0.023
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0121 0.2533
Treponema pallidum cell division protein FtsZ 0.0098 0.1521 1
Toxoplasma gondii hypothetical protein 0.005 0.0663 0.8883
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.002 0.0129 0.0245
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0016 0.0064 0.007
Loa Loa (eye worm) hypothetical protein 0.0016 0.0061 0.0067
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0034 0.0376 0.041
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0018 0.0095 0.01
Brugia malayi Steroid receptor seven-up type 2 0.0034 0.0376 0.041
Toxoplasma gondii target of rapamycin (TOR), putative 0.0019 0.0108 0.1447
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0034 0.0376 0.0394
Leishmania major tyrosine specific protein phosphatase, putative 0.0013 0.0018 0.0035
Brugia malayi Cell division protein ftsZ 0.0047 0.0616 0.0672
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0034 0.0376 0.118
Schistosoma mansoni hypothetical protein 0.0294 0.4987 0.5441
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0016 0.0061 0.0061
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0019 0.0108 0.0108
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0055 0.0747 0.0814
Schistosoma mansoni nuclear receptor nhr-48 0.0016 0.0061 0.0067
Loa Loa (eye worm) hypothetical protein 0.0018 0.0095 0.0104
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0055 0.0747 0.0814
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0053 0.0718 0.1367
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0146 0.2371 0.4512
Onchocerca volvulus Protein ultraspiracle homolog 0.0034 0.0376 0.118
Trypanosoma cruzi target of rapamycin kinase 3 0.0019 0.0108 0.0206
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0013 0.0018 0.0019
Schistosoma mansoni inositol monophosphatase 0.002 0.0129 0.014
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0016 0.0061 0.0142
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.002 0.0129 0.0245
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0034 0.0376 0.041
Echinococcus granulosus Nuclear hormone receptor HR96 0.0016 0.0061 0.0064
Entamoeba histolytica hypothetical protein 0.0046 0.0598 0.6543
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0013 0.0018 0.0019
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0013 0.0018 0.0018
Schistosoma mansoni nuclear receptor 0.0016 0.0061 0.0067
Schistosoma mansoni serine/threonine protein kinase 0.0064 0.0905 0.0987
Schistosoma mansoni tar DNA-binding protein 0.0101 0.1565 0.1707
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0108 0.2211
Trypanosoma cruzi tyrosine specific protein phosphatase, putative 0.0013 0.0018 0.0035
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0013 0.0018 0.002
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0108 0.2211
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0108 0.2211
Schistosoma mansoni thyroid hormone receptor 0.0101 0.1564 0.1706
Schistosoma mansoni jumonji domain containing protein 0.006 0.0846 0.0923
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0013 0.0018 0.002
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0013 0.0018 0.002
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0034 0.0376 0.041
Schistosoma mansoni rgs-gaip interacting protein gipc 0.0013 0.0018 0.002
Brugia malayi N-terminal motif family protein 0.0185 0.3052 0.333
Schistosoma mansoni protein tyrosine phosphatase 0.0013 0.0018 0.002
Loa Loa (eye worm) hypothetical protein 0.0013 0.0018 0.002
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0013 0.0018 0.002
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.002 0.0129 0.0245
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0016 0.0064 0.0064
Schistosoma mansoni nuclear hormone receptor 0.0016 0.0061 0.0067
Loa Loa (eye worm) hypothetical protein 0.0016 0.0064 0.007
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0013 0.0018 0.002
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0013 0.0018 0.0018
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0036 0.0425 0.0463
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0018 0.0095 0.0095
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0013 0.0018 0.0019
Entamoeba histolytica protein kinase, putative 0.0064 0.0905 1
Brugia malayi jmjC domain containing protein 0.0016 0.0064 0.007
Brugia malayi hypothetical protein 0.0016 0.0061 0.0067
Brugia malayi nuclear receptor NHR-88 0.0034 0.0376 0.041
Echinococcus granulosus tar DNA binding protein 0.0101 0.1565 0.1639
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0146 0.2371 0.4512
Schistosoma mansoni retinoic acid receptor RXR 0.0034 0.0376 0.041
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0108 0.2211
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0013 0.0018 0.0018
Loa Loa (eye worm) jmjC domain-containing protein 0.006 0.0846 0.0923
Brugia malayi Protein-tyrosine phosphatase 0.0013 0.0018 0.002
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0013 0.0018 0.0019
Trypanosoma cruzi tyrosine specific protein phosphatase, putative 0.0013 0.0018 0.0035
Schistosoma mansoni thyroid hormone receptor 0.0101 0.1564 0.1706
Brugia malayi Protein-tyrosine phosphatase 1 0.0013 0.0018 0.002
Loa Loa (eye worm) hypothetical protein 0.0034 0.0376 0.041
Loa Loa (eye worm) nuclear receptor NHR-67 0.0016 0.0061 0.0067
Echinococcus granulosus JmjC domain containing protein 4 0.0016 0.0064 0.0068
Echinococcus granulosus dual specificity 0.0064 0.0905 0.0948
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0034 0.0376 0.041
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0013 0.0018 0.002
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.053 0.9166 0.9602
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0019 0.0108 0.0206
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0013 0.0018 0.0018
Loa Loa (eye worm) protein-tyrosine phosphatase 0.053 0.9166 1

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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