Detailed information for compound 252788

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 283.408 | Formula: C19H25NO
  • H donors: 1 H acceptors: 1 LogP: 4.16 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: C#CCCCN1CC[C@]2(C(C1Cc1c2cc(cc1)O)C)C
  • InChi: 1S/C19H25NO/c1-4-5-6-10-20-11-9-19(3)14(2)18(20)12-15-7-8-16(21)13-17(15)19/h1,7-8,13-14,18,21H,5-6,9-12H2,2-3H3/t14?,18?,19-/m0/s1
  • InChiKey: QLVSIRINICYAHG-FPCQFERPSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Rattus norvegicus Sigma opioid receptor Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Leishmania mexicana C-8 sterol isomerase-like protein Get druggable targets OG5_131051 All targets in OG5_131051
Brugia malayi ERG2 and Sigma1 receptor like protein Get druggable targets OG5_131051 All targets in OG5_131051
Leishmania major C-8 sterol isomerase-like protein Get druggable targets OG5_131051 All targets in OG5_131051
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_131051 All targets in OG5_131051
Trypanosoma brucei gambiense C-8 sterol isomerase, putative Get druggable targets OG5_131051 All targets in OG5_131051
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_131051 All targets in OG5_131051
Trypanosoma brucei C-8 sterol isomerase, putative Get druggable targets OG5_131051 All targets in OG5_131051
Trypanosoma congolense C-8 sterol isomerase, putative Get druggable targets OG5_131051 All targets in OG5_131051
Leishmania infantum C-8 sterol isomerase-like protein Get druggable targets OG5_131051 All targets in OG5_131051
Trypanosoma congolense C-8 sterol isomerase, putative Get druggable targets OG5_131051 All targets in OG5_131051
Candida albicans sterol C8-C7 isomerase Get druggable targets OG5_131051 All targets in OG5_131051
Leishmania donovani C-8 sterol isomerase-like protein Get druggable targets OG5_131051 All targets in OG5_131051
Trypanosoma cruzi C-8 sterol isomerase, putative Get druggable targets OG5_131051 All targets in OG5_131051
Leishmania braziliensis C-8 sterol isomerase-like protein Get druggable targets OG5_131051 All targets in OG5_131051
Candida albicans sterol C8-C7 isomerase Get druggable targets OG5_131051 All targets in OG5_131051
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Giardia lamblia Kinase, CMGC MAPK 0.0061 0.0076 0.0805
Echinococcus multilocularis serotonin receptor 0.0602 0.1231 0.1231
Trichomonas vaginalis AGC family protein kinase 0.0051 0.0056 0.0595
Plasmodium vivax serine/threonine-specific protein kinase, putative 0.0113 0.0187 0.1889
Brugia malayi Immunoglobulin I-set domain containing protein 0.0037 0.0026 0.0026
Entamoeba histolytica protein kinase , putative 0.0302 0.0591 0.6248
Brugia malayi Protein kinase domain containing protein 0.0039 0.003 0.003
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0057 0.0068 0.0068
Trypanosoma cruzi histone deacetylase 1, putative 0.0468 0.0946 0.5118
Schistosoma mansoni tyrosine kinase 0.0039 0.003 0.003
Echinococcus granulosus rhodopsin orphan GPCR 0.0072 0.01 0.01
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0039 0.0029 0.0029
Trichomonas vaginalis AGC family protein kinase 0.0051 0.0056 0.0595
Loa Loa (eye worm) histone deacetylase 1 0.0468 0.0946 0.0943
Loa Loa (eye worm) hypothetical protein 0.0036 0.0023 0.002
Echinococcus granulosus glycine receptor subunit alpha 1 0.0067 0.0089 0.0089
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0072 0.01 0.01
Echinococcus granulosus CDC7 cell division cycle 7 0.0067 0.0089 0.0089
Onchocerca volvulus Putative nachr subunit 0.0067 0.0089 0.0877
Trypanosoma brucei histone deacetylase 2 0.0134 0.0232 0.1238
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0057 0.0068 0.0068
Loa Loa (eye worm) hypothetical protein 0.0122 0.0207 0.0204
Loa Loa (eye worm) hypothetical protein 0.0031 0.0012 0.0009
Echinococcus granulosus G2:mitotic specific cyclin B3 0.0032 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0072 0.01 0.0097
Echinococcus multilocularis aurora kinase A 0.0302 0.0591 0.0591
Entamoeba histolytica protein kinase, putative 0.0027 0.0004 0.0047
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0057 0.0068 0.0068
Echinococcus multilocularis alpha 1,6 mannosyl glycoprotein 0.4713 1 1
Loa Loa (eye worm) hypothetical protein 0.0072 0.01 0.0097
Entamoeba histolytica protein kinase 2, putative 0.003 0.0011 0.0113
Leishmania major C-8 sterol isomerase-like protein 0.0889 0.1844 1
Echinococcus granulosus glycine receptor subunit beta 0.0067 0.0089 0.0089
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0041 0.0034 0.0034
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0039 0.003 0.003
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0058 0.007 0.0357
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0072 0.01 0.0097
Schistosoma mansoni histone deacetylase 0.0468 0.0946 0.0946
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0053 0.0059 0.0299
Echinococcus multilocularis neuropeptides capa receptor 0.0072 0.01 0.01
Echinococcus multilocularis nAChR subunit 0.0067 0.0089 0.0089
Onchocerca volvulus 0.0318 0.0625 0.6422
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.0193 0.0358 0.0358
Schistosoma mansoni biogenic amine (5HT) receptor 0.0072 0.01 0.01
Echinococcus multilocularis epidermal growth factor receptor 0.023 0.0436 0.0436
Trypanosoma brucei aurora B kinase 0.0302 0.0591 0.3189
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0058 0.007 0.007
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0067 0.0089 0.0089
Schistosoma mansoni protein kinase 0.0302 0.0591 0.0591
Plasmodium falciparum histone deacetylase 1 0.0468 0.0946 1
Echinococcus multilocularis protein kinase c iota type 0.0034 0.002 0.002
Brugia malayi G-protein coupled receptor 0.0072 0.01 0.01
Schistosoma mansoni neuropeptide receptor 0.0072 0.01 0.01
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0072 0.01 0.01
Loa Loa (eye worm) GABA receptor subunit 0.0036 0.0023 0.002
Onchocerca volvulus 0.0072 0.01 0.0989
Loa Loa (eye worm) hypothetical protein 0.0072 0.01 0.0097
Trichomonas vaginalis CAMK family protein kinase 0.0105 0.0171 0.1813
Echinococcus granulosus mitogen activated protein kinase 0.0061 0.0076 0.0076
Entamoeba histolytica cell division protein kinase 2, putative 0.0053 0.0059 0.0625
Echinococcus granulosus neuropeptides capa receptor 0.0072 0.01 0.01
Brugia malayi SH2 domain containing protein 0.0039 0.003 0.003
Loa Loa (eye worm) LGC-31 protein 0.0067 0.0089 0.0086
Trichomonas vaginalis AGC family protein kinase 0.0302 0.0591 0.6248
Loa Loa (eye worm) hypothetical protein 0.0072 0.01 0.0097
Trichomonas vaginalis cyclin B3, putative 0.0032 0.0015 0.0155
Echinococcus granulosus tyrosine protein kinase Fyn 0.0057 0.0068 0.0068
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0031 0.0012 0.0012
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0067 0.0089 0.0089
Schistosoma mansoni nAChR subunit 0.0031 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.005 0.0053 0.005
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0027 0.0004 0.0004
Schistosoma mansoni titin 0.0038 0.0028 0.0028
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0061 0.0076 0.0392
Echinococcus granulosus biogenic amine 5HT receptor 0.0602 0.1231 0.1231
Echinococcus granulosus contactin 0.0038 0.0028 0.0028
Entamoeba histolytica protein kinase, putative 0.003 0.0011 0.0115
Schistosoma mansoni histone deacetylase hda2 0.0134 0.0232 0.0232
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0067 0.0089 0.0089
Brugia malayi serine/threonine protein kinase 6 0.0302 0.0591 0.0591
Brugia malayi Protein kinase domain containing protein 0.0039 0.003 0.003
Loa Loa (eye worm) TK/KIN16 protein kinase 0.038 0.0757 0.0754
Plasmodium falciparum histone deacetylase 2 0.0134 0.0232 0.2418
Brugia malayi RhoGAP domain containing protein 0.0027 0.0005 0.0005
Brugia malayi Variant SH3 domain containing protein 0.0039 0.003 0.003
Brugia malayi Serotonin receptor 0.0072 0.01 0.01
Schistosoma mansoni voltage-gated potassium channel 0.0042 0.0037 0.0037
Echinococcus granulosus G protein coupled receptor 139 0.0072 0.01 0.01
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0036 0.0023 0.0023
Echinococcus granulosus tachykinin peptides receptor 99D 0.0072 0.01 0.01
Schistosoma mansoni biogenic amine (5HT) receptor 0.0602 0.1231 0.1231
Brugia malayi SH2 domain containing protein 0.0039 0.003 0.003
Brugia malayi hypothetical protein 0.0072 0.01 0.01
Trichomonas vaginalis AGC family protein kinase 0.0302 0.0591 0.6248
Entamoeba histolytica p21-activated kinase 0.0027 0.0004 0.0047
Echinococcus granulosus roundabout 2 0.0053 0.0059 0.0059
Trichomonas vaginalis AGC family protein kinase 0.0302 0.0591 0.6248
Trichomonas vaginalis histone deacetylase, putative 0.0468 0.0946 1
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.018 0.033 0.0327
Schistosoma mansoni neuropeptide F-like receptor 0.0072 0.01 0.01
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.005 0.0053 0.0265
Leishmania major histone deacetylase, putative 0.0134 0.0232 0.1238
Loa Loa (eye worm) AUR protein kinase 0.0302 0.0591 0.0588
Echinococcus granulosus histone deacetylase 6 0.0134 0.0232 0.0232
Schistosoma mansoni nAChR subunit 0.0067 0.0089 0.0089
Toxoplasma gondii histone deacetylase HDAC1 0.0134 0.0232 0.2418
Brugia malayi hypothetical protein 0.0072 0.01 0.01
Onchocerca volvulus 0.0031 0.0013 0.0088
Echinococcus multilocularis histone deacetylase 6 0.0134 0.0232 0.0232
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0036 0.0023 0.0023
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.0031 0.0012 0.0012
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0105 0.0171 0.0168
Schistosoma mansoni serine/threonine protein kinase 0.0028 0.0007 0.0007
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0061 0.0076 0.0392
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0036 0.0024 0.0249
Schistosoma mansoni opsin-like receptor 0.0072 0.01 0.01
Echinococcus granulosus MAP kinase activated protein kinase 2 0.0193 0.0358 0.0358
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.005 0.0053 0.0053
Echinococcus multilocularis cyclin dependent kinase 1 0.0053 0.0059 0.0059
Trichomonas vaginalis CAMK family protein kinase 0.0057 0.0067 0.0712
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0053 0.0059 0.0056
Loa Loa (eye worm) hypothetical protein 0.0067 0.0089 0.0086
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0037 0.0026 0.0026
Schistosoma mansoni adenoreceptor 0.0072 0.01 0.01
Loa Loa (eye worm) CAMK/CAMKL/NIM1 protein kinase 0.0093 0.0145 0.0142
Loa Loa (eye worm) TK/FER protein kinase 0.0039 0.003 0.0027
Schistosoma mansoni serine/threonine protein kinase 0.0193 0.0358 0.0358
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0036 0.0023 0.0023
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0302 0.0591 0.6248
Trichomonas vaginalis histone deacetylase, putative 0.0468 0.0946 1
Brugia malayi serine/threonine kinase 12 0.0302 0.0591 0.0591
Loa Loa (eye worm) AGC/AKT protein kinase 0.0051 0.0056 0.0053
Leishmania major cyclin 0.0076 0.0109 0.0573
Leishmania major protein kinase A catalytic subunit 0.005 0.0053 0.0265
Echinococcus granulosus serine threonine protein kinase 0.0113 0.0187 0.0187
Entamoeba histolytica PH domain containing protein kinase, putative 0.0032 0.0015 0.016
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0061 0.0076 0.0392
Echinococcus multilocularis serotonin receptor 0.0602 0.1231 0.1231
Loa Loa (eye worm) TK/FER protein kinase 0.0039 0.003 0.0027
Echinococcus granulosus histone deacetylase 6 0.0134 0.0232 0.0232
Giardia lamblia Aurora kinase 0.0302 0.0591 0.6248
Trichomonas vaginalis STE family protein kinase 0.0113 0.0187 0.1981
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0468 0.0946 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0072 0.01 0.01
Echinococcus multilocularis histone deacetylase 8 0.0134 0.0232 0.0232
Schistosoma mansoni acetylcholine receptor subunit beta 0.0031 0.0012 0.0012
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0031 0.0012 0.0012
Schistosoma mansoni neuropeptide f receptor 76f 0.0072 0.01 0.01
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0137 0.024 0.1281
Leishmania major protein kinase A catalytic subunit isoform 2 0.005 0.0053 0.0265
Echinococcus multilocularis neuropeptides capa receptor 0.0072 0.01 0.01
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0061 0.0076 0.0073
Echinococcus granulosus rhodopsin orphan GPCR 0.0072 0.01 0.01
Loa Loa (eye worm) hypothetical protein 0.0053 0.0059 0.0056
Echinococcus granulosus rhodopsin orphan GPCR 0.0072 0.01 0.01
Loa Loa (eye worm) hypothetical protein 0.0031 0.0012 0.0009
Schistosoma mansoni beta-12-n-acetylglucosaminyltransferase II 0.4713 1 1
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0067 0.0089 0.0089
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0072 0.01 0.01
Trichomonas vaginalis CMGC family protein kinase 0.0067 0.0089 0.0944
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.0031 0.0012 0.0012
Echinococcus multilocularis g protein coupled receptor 0.0072 0.01 0.01
Brugia malayi map kinase activated protein kinase protein 2 0.0193 0.0358 0.0358
Loa Loa (eye worm) hypothetical protein 0.0036 0.0023 0.002
Brugia malayi hypothetical protein 0.0072 0.01 0.01
Echinococcus multilocularis G2:mitotic specific cyclin B3 0.0032 0.0015 0.0015
Onchocerca volvulus Putative titin 0.0031 0.0013 0.0088
Trichomonas vaginalis CAMK family protein kinase 0.0105 0.0171 0.1813
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0067 0.0089 0.0089
Loa Loa (eye worm) hypothetical protein 0.0072 0.01 0.0097
Schistosoma mansoni nAChR subunit 0.0031 0.0012 0.0012
Giardia lamblia Kinase, CMGC GSK 0.0058 0.007 0.0738
Brugia malayi Tyrosine-protein kinase abl-1 0.0138 0.024 0.024
Echinococcus multilocularis g protein coupled receptor 0.0072 0.01 0.01
Trypanosoma cruzi developmentally regulated phosphoprotein, putative 0.0122 0.0207 0.1101
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0076 0.0109 0.0109
Echinococcus granulosus serine:threonine protein kinase NIM1 0.0093 0.0145 0.0145
Trichomonas vaginalis cyclins, putative 0.0076 0.0109 0.1157
Brugia malayi Cation transporter family protein 0.0067 0.0089 0.0089
Echinococcus multilocularis cyclins 0.0032 0.0015 0.0015
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0051 0.0055 0.0052
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0028 0.0007 0.0007
Echinococcus multilocularis neuropeptide receptor 0.0072 0.01 0.01
Brugia malayi histone deacetylase 3 (HD3) 0.0468 0.0946 0.0946
Onchocerca volvulus 0.0067 0.0089 0.0877
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.005 0.0053 0.0053
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0053 0.0059 0.0584
Plasmodium vivax protein kinase Crk2 0.0053 0.0059 0.0518
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0067 0.0089 0.0089
Loa Loa (eye worm) hypothetical protein 0.0031 0.0012 0.0009
Echinococcus multilocularis serine threonine protein kinase 0.007 0.0096 0.0096
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0036 0.0023 0.0023
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0067 0.0089 0.0089
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0039 0.003 0.0316
Onchocerca volvulus 0.0072 0.01 0.0989
Brugia malayi excitatory GABA receptor EXP-1A 0.0067 0.0089 0.0089
Echinococcus granulosus growth factor receptor bound protein 2 0.0039 0.003 0.003
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0072 0.01 0.01
Echinococcus multilocularis rac serine:threonine kinase 0.0032 0.0015 0.0015
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0072 0.01 0.01
Brugia malayi Protein kinase domain containing protein 0.0051 0.0056 0.0056
Echinococcus multilocularis mitogen activated protein kinase 0.0061 0.0076 0.0076
Echinococcus multilocularis cyclin B 0.0076 0.0109 0.0109
Loa Loa (eye worm) hypothetical protein 0.0028 0.0007 0.0004
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0072 0.01 0.01
Schistosoma mansoni tyrosine kinase 0.0256 0.0493 0.0493
Echinococcus multilocularis tyrosine protein kinase shark 0.0256 0.0493 0.0493
Onchocerca volvulus 0.0039 0.003 0.0264
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0067 0.0089 0.0089
Loa Loa (eye worm) hypothetical protein 0.0072 0.01 0.0097
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0067 0.0089 0.0089
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0037 0.0026 0.0026
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0067 0.0089 0.0089
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0039 0.003 0.003
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0027 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0067 0.0089 0.0086
Loa Loa (eye worm) ACC-1 protein 0.0067 0.0089 0.0086
Schistosoma mansoni serine/threonine protein kinase 0.0036 0.0023 0.0023
Brugia malayi serine/threonine-protein kinase 6 0.0302 0.0591 0.0591
Echinococcus granulosus neuropeptide Y receptor 0.0072 0.01 0.01
Brugia malayi Cyclin, N-terminal domain containing protein 0.0076 0.0109 0.0109
Echinococcus multilocularis Immunoglobulin 0.0037 0.0026 0.0026
Echinococcus multilocularis CDC7 cell division cycle 7 0.0067 0.0089 0.0089
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0072 0.01 0.01
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0061 0.0076 0.0392
Echinococcus granulosus alpha 16 mannosyl glycoprotein 0.4713 1 1
Trichomonas vaginalis AGC family protein kinase 0.003 0.0012 0.0122
Schistosoma mansoni acetylcholine receptor-related 0.0031 0.0012 0.0012
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.005 0.0053 0.0265
Loa Loa (eye worm) hypothetical protein 0.0072 0.01 0.0097
Trichomonas vaginalis cyclin B, putative 0.0032 0.0015 0.0155
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0015 0.0155
Onchocerca volvulus Neuropeptide F receptor homolog 0.0072 0.01 0.0989
Loa Loa (eye worm) hypothetical protein 0.0602 0.1231 0.1229
Trichomonas vaginalis CAMK family protein kinase 0.0105 0.0171 0.1813
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0049 0.0052 0.051
Loa Loa (eye worm) hypothetical protein 0.0036 0.0023 0.002
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0072 0.01 0.01
Loa Loa (eye worm) TYRA-2 protein 0.0072 0.01 0.0097
Onchocerca volvulus 0.0072 0.01 0.0989
Echinococcus multilocularis cyclin dependent kinase 0.0053 0.0059 0.0059
Schistosoma mansoni cyclin B 0.0076 0.0109 0.0109
Trichomonas vaginalis cyclins, putative 0.0032 0.0015 0.0155
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.018 0.033 0.033
Echinococcus multilocularis hemicentin 1 0.0038 0.0028 0.0028
Echinococcus granulosus cyclins 0.0032 0.0015 0.0015
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0027 0.0005 0.0005
Brugia malayi hypothetical protein 0.0039 0.003 0.003
Schistosoma mansoni serine/threonine-protein kinase 0.0032 0.0015 0.0015
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0072 0.01 0.01
Loa Loa (eye worm) hypothetical protein 0.0067 0.0089 0.0086
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0053 0.0059 0.0299
Loa Loa (eye worm) hypothetical protein 0.0031 0.0012 0.0009
Schistosoma mansoni tyrosine kinase 0.0034 0.0019 0.0019
Trichomonas vaginalis CAMK family protein kinase 0.0057 0.0067 0.0712
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0072 0.01 0.01
Brugia malayi histone deacetylase 11 0.0134 0.0232 0.0232
Trichomonas vaginalis AGC family protein kinase 0.0051 0.0056 0.0595
Trypanosoma cruzi cyclin, putative 0.0076 0.0109 0.0573
Trypanosoma cruzi histone deacetylase 1, putative 0.0468 0.0946 0.5118
Entamoeba histolytica protein kinase, putative 0.0051 0.0056 0.0595
Echinococcus multilocularis c src tyrosine kinase 0.0057 0.0068 0.0068
Entamoeba histolytica protein kinase domain containing protein 0.0027 0.0004 0.0043
Loa Loa (eye worm) hypothetical protein 0.0084 0.0126 0.0123
Brugia malayi Variant SH3 domain containing protein 0.0039 0.003 0.003
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0137 0.024 0.0237
Brugia malayi Protein kinase domain containing protein 0.0028 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0072 0.01 0.0097
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0067 0.0089 0.0089
Loa Loa (eye worm) hypothetical protein 0.0072 0.01 0.0097
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0302 0.0591 0.6205
Onchocerca volvulus Basement membrane proteoglycan homolog 0.0038 0.0028 0.0242
Trichomonas vaginalis cyclin B, putative 0.0076 0.0109 0.1157
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.005 0.0053 0.0265
Brugia malayi Immunoglobulin I-set domain containing protein 0.038 0.0757 0.0757
Brugia malayi putative neuropeptide receptor NPR1 0.0072 0.01 0.01
Brugia malayi Cation transporter family protein 0.0067 0.0089 0.0089
Schistosoma mansoni neurotransmitter gated ion channel 0.0036 0.0023 0.0023
Echinococcus multilocularis mitogen activated protein kinase 11 0.0137 0.024 0.024
Trichomonas vaginalis CMGC family protein kinase 0.0061 0.0076 0.0805
Loa Loa (eye worm) hypothetical protein 0.0072 0.01 0.0097
Echinococcus granulosus neuropeptide receptor 0.0072 0.01 0.01
Schistosoma mansoni serine/threonine-protein kinase 0.0032 0.0015 0.0015
Entamoeba histolytica cyclin, putative 0.0032 0.0015 0.0155
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0072 0.01 0.01
Schistosoma mansoni serine/threonine protein kinase 0.0302 0.0591 0.0591
Echinococcus multilocularis Immunoglobulin 0.0037 0.0026 0.0026
Onchocerca volvulus 0.0067 0.0089 0.0877
Loa Loa (eye worm) hypothetical protein 0.0037 0.0026 0.0023
Schistosoma mansoni voltage-gated potassium channel 0.0042 0.0037 0.0037
Loa Loa (eye worm) hypothetical protein 0.0072 0.01 0.0097
Leishmania major histone deacetylase, putative 0.0134 0.0232 0.1238
Trypanosoma brucei pyruvate dehydrogenase (lipoamide) kinase, putative 0.0043 0.0038 0.0182
Echinococcus granulosus tm gpcr rhodopsin 0.0697 0.1433 0.1433
Loa Loa (eye worm) hypothetical protein 0.0067 0.0089 0.0086
Schistosoma mansoni amine GPCR 0.0072 0.01 0.01
Loa Loa (eye worm) TK/FER protein kinase 0.0039 0.003 0.0027
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0067 0.0089 0.0089
Echinococcus granulosus glycine receptor subunit alpha 1 0.0067 0.0089 0.0089
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0072 0.01 0.01
Entamoeba histolytica serine/threonine protein kinase, putative 0.0105 0.0171 0.1813
Echinococcus granulosus neuropeptide receptor 0.0072 0.01 0.01
Schistosoma mansoni atypical protein kinase C 0.0034 0.002 0.002
Echinococcus multilocularis nAChR subunit 0.0036 0.0023 0.0023
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0067 0.0089 0.0089
Schistosoma mansoni cyclin B3 0.0032 0.0015 0.0015
Onchocerca volvulus 0.0067 0.0089 0.0877
Trypanosoma cruzi histone deacetylase, putative 0.0134 0.0232 0.1238
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0028 0.0007 0.0007
Giardia lamblia Cyclin A 0.0032 0.0015 0.0155
Brugia malayi intracellular kinase 0.0058 0.007 0.007
Loa Loa (eye worm) hypothetical protein 0.0072 0.01 0.0097
Echinococcus multilocularis mitogen activated protein kinase 14 0.0137 0.024 0.024
Brugia malayi Protein kinase domain containing protein 0.0039 0.003 0.003
Onchocerca volvulus 0.0072 0.01 0.0989
Echinococcus granulosus glycine receptor subunit alpha 1 0.0067 0.0089 0.0089
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0061 0.0076 0.0392
Echinococcus granulosus rhodopsin orphan GPCR 0.0072 0.01 0.01
Brugia malayi Histone deacetylase family protein 0.0134 0.0232 0.0232
Giardia lamblia Kinase, CMGC CDK 0.0053 0.0059 0.0625
Loa Loa (eye worm) histone deacetylase 7A 0.0134 0.0232 0.0229
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0072 0.01 0.01
Echinococcus granulosus tyrosine protein kinase Fyn 0.0057 0.0068 0.0068
Loa Loa (eye worm) hypothetical protein 0.0072 0.01 0.0097
Loa Loa (eye worm) hypothetical protein 0.0031 0.0012 0.0009
Trichomonas vaginalis cyclin A, putative 0.0076 0.0109 0.1157
Loa Loa (eye worm) histone deacetylase 11 0.0134 0.0232 0.0229
Schistosoma mansoni nAChR subunit 0.0067 0.0089 0.0089
Schistosoma mansoni biogenic amine receptor 0.0072 0.01 0.01
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0072 0.01 0.01
Loa Loa (eye worm) hypothetical protein 0.0072 0.01 0.0097
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0061 0.0076 0.0392
Echinococcus granulosus activin receptor type 0.0027 0.0004 0.0004
Brugia malayi Dopamine receptor 0.0072 0.01 0.01
Trichomonas vaginalis CMGC family protein kinase 0.0067 0.0089 0.0944
Schistosoma mansoni serine/threonine protein kinase 0.0053 0.0059 0.0059
Schistosoma mansoni amine GPCR 0.0072 0.01 0.01
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0058 0.007 0.007
Onchocerca volvulus 0.0067 0.0089 0.0877
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.005 0.0053 0.0265
Loa Loa (eye worm) hypothetical protein 0.0044 0.0042 0.0039
Brugia malayi Variant SH3 domain containing protein 0.0027 0.0005 0.0005
Loa Loa (eye worm) TK/FER protein kinase 0.0039 0.003 0.0027
Loa Loa (eye worm) hypothetical protein 0.0072 0.01 0.0097
Echinococcus multilocularis glycine receptor subunit beta 0.0067 0.0089 0.0089
Trichomonas vaginalis CMGC family protein kinase 0.0061 0.0076 0.0805
Schistosoma mansoni tyrosine kinase 0.0057 0.0068 0.0068
Loa Loa (eye worm) hypothetical protein 0.0047 0.0046 0.0043
Echinococcus multilocularis cyclins 0.0032 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0072 0.01 0.0097
Loa Loa (eye worm) hypothetical protein 0.0072 0.01 0.0097
Echinococcus granulosus Pyruvate dehydrogenase lipoamide kinase 0.0122 0.0207 0.0207
Schistosoma mansoni tyrosine kinase 0.023 0.0436 0.0436
Echinococcus granulosus neuroglian 0.0046 0.0045 0.0045
Brugia malayi Histone deacetylase 1 0.0468 0.0946 0.0946
Schistosoma mansoni hypothetical protein 0.0031 0.0013 0.0013
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0067 0.0089 0.0089
Brugia malayi neuropeptide F receptor 0.0072 0.01 0.01
Schistosoma mansoni histone deacetylase hda2 0.0134 0.0232 0.0232
Loa Loa (eye worm) hypothetical protein 0.0067 0.0089 0.0086
Entamoeba histolytica protein kinase, putative 0.0051 0.0056 0.0595
Echinococcus multilocularis cyclin b3 0.0032 0.0015 0.0015
Echinococcus multilocularis somatostatin receptor 0.0072 0.01 0.01
Schistosoma mansoni histone deacetylase 0.0468 0.0946 0.0946
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0027 0.0005 0.0002
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0159 0.0286 0.0286
Entamoeba histolytica protein kinase, putative 0.0302 0.0591 0.6248
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0067 0.0089 0.0089
Schistosoma mansoni tyrosine kinase 0.0229 0.0435 0.0435
Trichomonas vaginalis CAMK family protein kinase 0.0105 0.0171 0.1813
Echinococcus multilocularis cyclins 0.0032 0.0015 0.0015
Brugia malayi Protein kinase domain containing protein 0.018 0.033 0.033
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0026 0.0003 0.0003
Schistosoma mansoni serine/threonine protein kinase 0.005 0.0053 0.0053
Loa Loa (eye worm) AUR protein kinase 0.0302 0.0591 0.0588
Echinococcus granulosus cyclins 0.0032 0.0015 0.0015
Brugia malayi G protein-coupled receptor F59B2.13 0.0072 0.01 0.01
Echinococcus granulosus orexin receptor type 2 0.0072 0.01 0.01
Loa Loa (eye worm) hypothetical protein 0.0072 0.01 0.0097
Schistosoma mansoni growth hormone secretagogue receptor 0.0072 0.01 0.01
Trypanosoma brucei mitotic cyclin 6 0.0076 0.0109 0.0573
Schistosoma mansoni adapter molecule crk 0.0039 0.003 0.003
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0041 0.0034 0.0034
Echinococcus granulosus neuropeptides capa receptor 0.0072 0.01 0.01
Loa Loa (eye worm) hypothetical protein 0.0036 0.0023 0.002
Loa Loa (eye worm) hypothetical protein 0.0036 0.0023 0.002
Plasmodium falciparum cyclin 0.0032 0.0015 0.0112
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0039 0.0029 0.0029
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0058 0.007 0.0067
Entamoeba histolytica cyclin, putative 0.0076 0.0109 0.1157
Loa Loa (eye worm) hypothetical protein 0.0072 0.01 0.0097
Loa Loa (eye worm) ACC-1 protein 0.0067 0.0089 0.0086
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0072 0.01 0.01
Onchocerca volvulus 0.0093 0.0145 0.1455
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0122 0.0207 0.0207
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0072 0.01 0.01
Loa Loa (eye worm) hypothetical protein 0.0072 0.01 0.0097
Entamoeba histolytica PH domain containing protein kinase, putative 0.0052 0.0057 0.0606
Echinococcus multilocularis growth factor receptor bound protein 2 0.0039 0.003 0.003
Plasmodium falciparum histone deacetylase, putative 0.0134 0.0232 0.2418
Onchocerca volvulus 0.0072 0.01 0.0989
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0053 0.0059 0.0056
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0067 0.0089 0.0086
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0105 0.0171 0.0171
Onchocerca volvulus 0.0039 0.003 0.0264
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0072 0.01 0.01
Schistosoma mansoni serine/threonine protein kinase 0.0028 0.0007 0.0007
Echinococcus multilocularis mitogen activated protein kinase 11 0.0137 0.024 0.024
Echinococcus granulosus aurora kinase A 0.0302 0.0591 0.0591
Echinococcus multilocularis allatostatin A receptor 0.0072 0.01 0.01
Echinococcus granulosus histone deacetylase 8 0.0134 0.0232 0.0232
Loa Loa (eye worm) hypothetical protein 0.0031 0.0012 0.0009
Schistosoma mansoni opsin-like receptor 0.0072 0.01 0.01
Trypanosoma cruzi pyruvate dehydrogenase (lipoamide) kinase, putative 0.0043 0.0038 0.0182
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0072 0.01 0.01
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.0031 0.0012 0.0009
Entamoeba histolytica protein kinase, putative 0.0113 0.0187 0.1981
Loa Loa (eye worm) hypothetical protein 0.0084 0.0126 0.0123
Brugia malayi cell division control protein 2 homolog 0.0093 0.0145 0.0145
Schistosoma mansoni myosin xvIII 0.0072 0.01 0.01
Echinococcus multilocularis tyrosine protein kinase ABL1 0.025 0.048 0.048
Giardia lamblia Kinase, CMGC CDK 0.0053 0.0059 0.0625
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.005 0.0053 0.0518
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0122 0.0207 0.0207
Loa Loa (eye worm) neuropeptide F receptor 0.0072 0.01 0.0097
Echinococcus multilocularis rhodopsin orphan GPCR 0.0072 0.01 0.01
Echinococcus granulosus epidermal growth factor receptor 0.023 0.0436 0.0436
Trypanosoma brucei histone deacetylase, putative 0.0134 0.0232 0.1238
Brugia malayi Cation transporter family protein 0.0067 0.0089 0.0089
Echinococcus granulosus allatostatin A receptor 0.0072 0.01 0.01
Onchocerca volvulus 0.0031 0.0012 0.0083
Echinococcus granulosus cyclins 0.0032 0.0015 0.0015
Echinococcus granulosus cyclins 0.0032 0.0015 0.0015
Trypanosoma brucei protein kinase, putative 0.0058 0.007 0.0357
Schistosoma mansoni neuropeptide receptor 0.0072 0.01 0.01
Echinococcus multilocularis neuropeptide Y receptor 0.0072 0.01 0.01
Schistosoma mansoni vesicular amine transporter 0.004 0.0032 0.0032
Loa Loa (eye worm) G-protein coupled receptor 0.0072 0.01 0.0097
Echinococcus granulosus neuropeptide s receptor 0.0072 0.01 0.01
Schistosoma mansoni tyrosine kinase 0.0159 0.0286 0.0286
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0039 0.003 0.003
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0468 0.0946 1
Toxoplasma gondii histone deacetylase HDAC5 0.0134 0.0232 0.2418
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0105 0.0171 0.091
Loa Loa (eye worm) hypothetical protein 0.0067 0.0089 0.0086
Echinococcus granulosus cyclin dependent kinase 0.0053 0.0059 0.0059
Echinococcus granulosus hypothetical protein 0.0072 0.01 0.01
Echinococcus granulosus cyclin B 0.0076 0.0109 0.0109
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0137 0.024 0.1281
Schistosoma mansoni serine/threonine protein kinase 0.0052 0.0057 0.0057
Schistosoma mansoni serine/threonine protein kinase 0.0093 0.0145 0.0145
Echinococcus granulosus mitogen activated protein kinase 14 0.0137 0.024 0.024
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0072 0.01 0.01
Brugia malayi Cyclin, N-terminal domain containing protein 0.0076 0.0109 0.0109
Echinococcus multilocularis rhodopsin orphan GPCR 0.0072 0.01 0.01
Giardia lamblia Kinase, AGC PKA 0.003 0.0011 0.0113
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0199 0.0371 0.0371
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0072 0.01 0.01
Onchocerca volvulus 0.0067 0.0089 0.0879
Loa Loa (eye worm) hypothetical protein 0.0072 0.01 0.0097
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0058 0.007 0.0357
Brugia malayi protein-tyrosine kinase 0.0039 0.003 0.003
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0468 0.0946 1
Brugia malayi Protein kinase domain containing protein 0.0053 0.0059 0.0059
Schistosoma mansoni neuropeptide F-like receptor 0.0072 0.01 0.01
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0302 0.0591 0.0591
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0072 0.01 0.01
Brugia malayi P38 map kinase family protein 2 0.0137 0.024 0.024
Echinococcus multilocularis cyclins 0.0032 0.0015 0.0015
Echinococcus granulosus Immunoglobulin 0.0037 0.0026 0.0026
Loa Loa (eye worm) hypothetical protein 0.0033 0.0018 0.0015
Loa Loa (eye worm) hypothetical protein 0.0072 0.01 0.0097
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0067 0.0089 0.0089
Toxoplasma gondii AGC kinase 0.0049 0.0052 0.0506
Echinococcus multilocularis fmrfamide receptor 0.0072 0.01 0.01
Schistosoma mansoni hypothetical protein 0.0072 0.01 0.01
Trypanosoma cruzi polo-like protein kinase, putative 0.0105 0.0171 0.091
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.005 0.0053 0.0265
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0072 0.01 0.01
Echinococcus granulosus neuropeptide Y receptor 0.0072 0.01 0.01
Loa Loa (eye worm) hypothetical protein 0.0067 0.0089 0.0086
Loa Loa (eye worm) histone deacetylase 3 0.0468 0.0946 0.0943
Brugia malayi G-protein coupled receptor 0.0072 0.01 0.01
Trichomonas vaginalis CAMK family protein kinase 0.0105 0.0171 0.1813
Brugia malayi Tachykinin-like peptides receptor 99D 0.0072 0.01 0.01
Loa Loa (eye worm) hypothetical protein 0.0031 0.0012 0.0009
Plasmodium vivax histone deacetylase 1, putative 0.0468 0.0946 1
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0119 0.02 0.02
Loa Loa (eye worm) hypothetical protein 0.4713 1 1
Brugia malayi hypothetical protein 0.0031 0.0012 0.0012
Leishmania major protein kinase, putative 0.0302 0.0591 0.3189
Echinococcus multilocularis telomerase reverse transcriptase subunit 0.004 0.0033 0.0033
Echinococcus granulosus cyclin dependent kinase 5 0.0053 0.0059 0.0059
Loa Loa (eye worm) hypothetical protein 0.0067 0.0089 0.0086
Toxoplasma gondii aurora kinase 0.0302 0.0591 0.6231
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0697 0.1433 0.1433
Loa Loa (eye worm) hypothetical protein 0.0072 0.01 0.0097
Echinococcus multilocularis rhodopsin orphan GPCR 0.0072 0.01 0.01
Echinococcus granulosus tm gpcr rhodopsin 0.0072 0.01 0.01
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0028 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0031 0.0012 0.0009
Loa Loa (eye worm) neuropeptide F receptor 0.0072 0.01 0.0097
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.005 0.0053 0.0265
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0028 0.0007 0.0004
Loa Loa (eye worm) hypothetical protein 0.0072 0.01 0.0097
Echinococcus granulosus rhodopsin orphan GPCR 0.0072 0.01 0.01
Loa Loa (eye worm) hypothetical protein 0.0044 0.0041 0.0038
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0026 0.0003 0.0003
Echinococcus multilocularis sex peptide receptor 0.0072 0.01 0.01
Brugia malayi putative neuropeptide receptor 0.0072 0.01 0.01
Giardia lamblia Hypothetical protein 0.0032 0.0015 0.0155
Echinococcus granulosus cyclin b3 0.0032 0.0015 0.0015
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0889 0.1844 1
Trichomonas vaginalis cyclin D, putative 0.0032 0.0015 0.0155
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0067 0.0089 0.0089
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0072 0.01 0.01
Brugia malayi Protein kinase domain containing protein 0.0067 0.0089 0.0089
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0039 0.003 0.003
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0067 0.0089 0.0089
Trichomonas vaginalis CAMK family protein kinase 0.0105 0.0171 0.1813
Trichomonas vaginalis AGC family protein kinase 0.0051 0.0056 0.0595
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.0031 0.0012 0.0012
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0057 0.0068 0.0068
Loa Loa (eye worm) hypothetical protein 0.0067 0.0089 0.0086
Loa Loa (eye worm) hypothetical protein 0.0037 0.0026 0.0023
Loa Loa (eye worm) hypothetical protein 0.0067 0.0089 0.0086
Echinococcus granulosus c src tyrosine kinase 0.0057 0.0068 0.0068
Echinococcus granulosus g-protein coupled receptor 0.0072 0.01 0.01
Schistosoma mansoni protein kinase 0.0027 0.0004 0.0004
Trichomonas vaginalis AGC family protein kinase 0.0051 0.0056 0.0595
Loa Loa (eye worm) TK protein kinase 0.0127 0.0218 0.0215
Loa Loa (eye worm) hypothetical protein 0.0455 0.0916 0.0914
Echinococcus multilocularis G-protein coupled receptor, putative 0.0072 0.01 0.01
Brugia malayi hypothetical protein 0.0072 0.01 0.01
Brugia malayi p70 ribosomal S6 kinase beta 0.0049 0.0052 0.0052
Brugia malayi Protein kinase domain containing protein 0.0199 0.0371 0.0371
Echinococcus multilocularis serine:threonine protein kinase N2 0.0028 0.0007 0.0007
Schistosoma mansoni histone deacetylase 4 5 0.0134 0.0232 0.0232
Loa Loa (eye worm) SRC-1 0.0057 0.0068 0.0065
Echinococcus granulosus RNA directed DNA polymerase 0.004 0.0033 0.0033
Trypanosoma cruzi aurora B kinase, putative 0.0302 0.0591 0.3189
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0067 0.0089 0.0089
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0072 0.01 0.01
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.0031 0.0012 0.0012
Trypanosoma cruzi cdc2-related kinase 1 0.0053 0.0059 0.0299
Toxoplasma gondii AGC kinase 0.005 0.0053 0.0518
Schistosoma mansoni tyrosine kinase 0.0057 0.0068 0.0068
Echinococcus multilocularis rhodopsin orphan GPCR 0.0072 0.01 0.01
Onchocerca volvulus 0.0072 0.01 0.0989
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0067 0.0089 0.0089
Echinococcus multilocularis glycine receptor subunit beta 0.0067 0.0089 0.0089
Brugia malayi hypothetical protein 0.0072 0.01 0.01
Brugia malayi ORL1-like opioid receptor 0.0072 0.01 0.01
Loa Loa (eye worm) hypothetical protein 0.0037 0.0026 0.0023
Onchocerca volvulus 0.0067 0.0089 0.0877
Trypanosoma cruzi histone deacetylase, putative 0.0134 0.0232 0.1238
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0067 0.0089 0.0089
Echinococcus granulosus protein kinase C gamma type 0.007 0.0096 0.0096
Echinococcus multilocularis orexin receptor type 2 0.0072 0.01 0.01
Trichomonas vaginalis CMGC family protein kinase 0.0053 0.0059 0.0625
Trichomonas vaginalis AGC family protein kinase 0.0051 0.0056 0.0595
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0072 0.01 0.01
Echinococcus granulosus Protein kinase C brain isozyme 0.0076 0.0109 0.0109
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.003 0.0011 0.0011
Brugia malayi histone deacetylase 1 (HD1) 0.0468 0.0946 0.0946
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0057 0.0068 0.0068
Loa Loa (eye worm) hypothetical protein 0.0072 0.01 0.0097
Schistosoma mansoni protein kinase 0.0027 0.0004 0.0004
Entamoeba histolytica PH domain containing protein kinase, putative 0.0052 0.0057 0.0606
Giardia lamblia Kinase, PLK 0.0105 0.0171 0.1813
Loa Loa (eye worm) hypothetical protein 0.0067 0.0089 0.0086
Brugia malayi Protein kinase domain containing protein 0.0039 0.003 0.003
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.005 0.0053 0.0053
Echinococcus multilocularis G protein coupled receptor 139 0.0072 0.01 0.01
Schistosoma mansoni hypothetical protein 0.0072 0.01 0.01
Schistosoma mansoni serine/threonine protein kinase 0.0113 0.0187 0.0187
Toxoplasma gondii histone deacetylase HDAC4 0.0134 0.0232 0.2418
Echinococcus granulosus 7TM GPCR rhodopsin 0.0072 0.01 0.01
Loa Loa (eye worm) hypothetical protein 0.0072 0.01 0.0097
Schistosoma mansoni tyrosine kinase 0.0141 0.0248 0.0248
Echinococcus multilocularis cyclins 0.0032 0.0015 0.0015
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0039 0.003 0.003
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0105 0.0171 0.0171
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0031 0.0012 0.0012
Echinococcus multilocularis cyclins 0.0032 0.0015 0.0015
Echinococcus multilocularis g protein coupled receptor 0.0072 0.01 0.01
Onchocerca volvulus 0.0039 0.003 0.0264
Trichomonas vaginalis CMGC family protein kinase 0.0061 0.0076 0.0805
Loa Loa (eye worm) hypothetical protein 0.0072 0.01 0.0097
Loa Loa (eye worm) hypothetical protein 0.0072 0.01 0.0097
Loa Loa (eye worm) hypothetical protein 0.0067 0.0089 0.0086
Trichomonas vaginalis cyclins, putative 0.0052 0.0058 0.0613
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0072 0.01 0.01
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0072 0.01 0.01
Schistosoma mansoni serine/threonine protein kinase 0.0028 0.0007 0.0007
Echinococcus granulosus g protein coupled receptor 0.0072 0.01 0.01
Echinococcus multilocularis g-protein coupled receptor 0.0072 0.01 0.01
Schistosoma mansoni amine GPCR 0.0072 0.01 0.01
Echinococcus granulosus histone deacetylase 7 0.0134 0.0232 0.0232
Leishmania major histone deacetylase, putative 0.0468 0.0946 0.5118
Loa Loa (eye worm) hypothetical protein 0.0072 0.01 0.0097
Brugia malayi serine/threonine-protein kinase PAK 7 0.0196 0.0364 0.0364
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.003 0.0011 0.0011
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0036 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0067 0.0089 0.0086
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0039 0.0029 0.0026
Echinococcus granulosus glycine receptor subunit beta 0.0067 0.0089 0.0089
Leishmania major protein kinase A catalytic subunit isoform 1 0.005 0.0053 0.0265
Echinococcus granulosus NDR protein kinase 0.0028 0.0007 0.0007
Brugia malayi G protein-coupled receptor 0.0072 0.01 0.01
Echinococcus granulosus g protein coupled receptor 0.0072 0.01 0.01
Loa Loa (eye worm) hypothetical protein 0.0072 0.01 0.0097
Trypanosoma brucei C-8 sterol isomerase, putative 0.0889 0.1844 1
Schistosoma mansoni serine/threonine protein kinase 0.0076 0.0109 0.0109
Loa Loa (eye worm) TK/FER protein kinase 0.0039 0.003 0.0027
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0072 0.01 0.01
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0072 0.01 0.0989
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0058 0.007 0.007
Echinococcus multilocularis cyclin dependent kinase 1 0.0053 0.0059 0.0059
Echinococcus granulosus NCK adaptor protein 0.0039 0.003 0.003
Entamoeba histolytica protein kinase, putative 0.0049 0.0052 0.0547
Onchocerca volvulus 0.0072 0.01 0.0989
Trypanosoma cruzi cdc2-related kinase 1 0.0053 0.0059 0.0299
Echinococcus granulosus defective proboscis extension response 0.0037 0.0026 0.0026
Echinococcus multilocularis neuropeptide FF receptor 2 0.0072 0.01 0.01
Echinococcus multilocularis mitogen activated protein kinase 14 0.0137 0.024 0.024
Loa Loa (eye worm) hypothetical protein 0.0072 0.01 0.0097
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0067 0.0089 0.0089
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0031 0.0012 0.0012
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.003 0.0011 0.007
Onchocerca volvulus 0.0031 0.0012 0.0083
Loa Loa (eye worm) cyclin domain-containing protein 0.0032 0.0015 0.0012
Brugia malayi Histone deacetylase family protein 0.0134 0.0232 0.0232
Onchocerca volvulus 0.0072 0.01 0.0989
Schistosoma mansoni amine GPCR 0.0072 0.01 0.01
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0058 0.007 0.0698
Onchocerca volvulus 0.0072 0.01 0.0989
Onchocerca volvulus 0.0072 0.01 0.0989
Schistosoma mansoni histone deacetylase 1 2 3 0.0134 0.0232 0.0232
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0072 0.01 0.01
Trichomonas vaginalis cyclin B, putative 0.0076 0.0109 0.1157
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0072 0.01 0.01
Trichomonas vaginalis AGC family protein kinase 0.0051 0.0056 0.0595
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0302 0.0591 0.6248
Echinococcus multilocularis tyrosine protein kinase Blk 0.0039 0.003 0.003
Entamoeba histolytica protein kinase, putative 0.0302 0.0591 0.6248
Echinococcus multilocularis RNA directed DNA polymerase 0.004 0.0033 0.0033
Trypanosoma brucei histone deacetylase 1 0.0468 0.0946 0.5118
Entamoeba histolytica cell division protein kinase 2, putative 0.0053 0.0059 0.0625
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0028 0.0007 0.0007
Schistosoma mansoni pyruvate dehydrogenase 0.0122 0.0207 0.0207
Schistosoma mansoni histamine h1 receptor 0.0072 0.01 0.01
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0036 0.0023 0.0023
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.018 0.033 0.033
Trypanosoma cruzi cyclin 6, putative 0.0076 0.0109 0.0573
Brugia malayi Dopamine receptor protein 2 0.0072 0.01 0.01
Entamoeba histolytica protein kinase domain containing protein 0.0058 0.007 0.0738
Loa Loa (eye worm) hypothetical protein 0.0072 0.01 0.0097
Echinococcus granulosus cyclin dependent kinase 1 0.0053 0.0059 0.0059
Echinococcus multilocularis histone deacetylase 7 0.0134 0.0232 0.0232
Brugia malayi hypothetical protein 0.0031 0.0012 0.0012
Schistosoma mansoni neurotransmitter gated ion channel 0.0031 0.0012 0.0012
Loa Loa (eye worm) acetylcholine receptor protein 0.0031 0.0012 0.0009
Trichomonas vaginalis CAMK family protein kinase 0.0105 0.0171 0.1813
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0067 0.0089 0.0089
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0031 0.0012 0.0012
Schistosoma mansoni tyrosine kinase 0.0057 0.0068 0.0068
Schistosoma mansoni tyrosine kinase 0.0141 0.0248 0.0248
Trichomonas vaginalis cyclin D, putative 0.0032 0.0015 0.0155
Brugia malayi Melatonin receptor type 1A 0.0072 0.01 0.01
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0067 0.0089 0.0089
Echinococcus granulosus histone deacetylase 0.0134 0.0232 0.0232
Trichomonas vaginalis AGC family protein kinase 0.0302 0.0591 0.6248
Trypanosoma brucei cdc2-related kinase 1 0.0053 0.0059 0.0299
Echinococcus granulosus serine threonine protein kinase nrc 0.003 0.0011 0.0011
Echinococcus granulosus insulin receptor 0.0199 0.0371 0.0371
Trichomonas vaginalis cyclin B, putative 0.0076 0.0109 0.1157
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0067 0.0089 0.0089
Onchocerca volvulus 0.0031 0.0012 0.0083
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0072 0.01 0.0097
Schistosoma mansoni histone deacetylase 4 5 0.0134 0.0232 0.0232
Loa Loa (eye worm) hypothetical protein 0.0134 0.0232 0.0229
Onchocerca volvulus 0.0072 0.01 0.0989
Loa Loa (eye worm) AGC/PKA protein kinase 0.005 0.0053 0.005
Echinococcus multilocularis cyclins 0.0032 0.0015 0.0015
Brugia malayi SRC-1 0.0057 0.0068 0.0068
Brugia malayi GnHR receptor homolog 0.0072 0.01 0.01
Trypanosoma cruzi histone deacetylase, putative 0.0134 0.0232 0.1238
Loa Loa (eye worm) TK/ABL protein kinase 0.025 0.048 0.0477
Echinococcus granulosus tyrosine kinase 0.0039 0.003 0.003
Loa Loa (eye worm) hypothetical protein 0.0889 0.1844 0.1841
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0029 0.001 0.001
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0027 0.0005 0.0005
Loa Loa (eye worm) AUR protein kinase 0.0302 0.0591 0.0588
Loa Loa (eye worm) hypothetical protein 0.0072 0.01 0.0097
Loa Loa (eye worm) AGC/NDR protein kinase 0.0028 0.0007 0.0004
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0067 0.0089 0.0089
Loa Loa (eye worm) TK/FER protein kinase 0.0039 0.003 0.0027
Brugia malayi follicle stimulating hormone receptor 0.0072 0.01 0.01
Loa Loa (eye worm) hypothetical protein 0.0099 0.0157 0.0154
Brugia malayi hypothetical protein 0.0072 0.01 0.01
Trichomonas vaginalis AGC family protein kinase 0.0028 0.0007 0.0074
Toxoplasma gondii AGC kinase 0.005 0.0053 0.0518
Schistosoma mansoni tyrosine kinase 0.0159 0.0286 0.0286
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0058 0.007 0.0067
Schistosoma mansoni serine/threonine protein kinase 0.0067 0.0089 0.0089
Loa Loa (eye worm) TK/INSR protein kinase 0.0199 0.0371 0.0368
Entamoeba histolytica histone deacetylase, putative 0.0468 0.0946 1
Echinococcus granulosus fmrfamide receptor 0.0072 0.01 0.01
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0302 0.0591 0.6248
Echinococcus multilocularis histone deacetylase 6 0.0134 0.0232 0.0232
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0031 0.0012 0.0012
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0067 0.0089 0.0089
Schistosoma mansoni nAChR subunit 0.0067 0.0089 0.0089
Trichomonas vaginalis histone deacetylase, putative 0.0468 0.0946 1
Loa Loa (eye worm) hypothetical protein 0.0037 0.0026 0.0023
Schistosoma mansoni nck2/grb4 0.0039 0.003 0.003
Leishmania major histone deacetylase, putative 0.0468 0.0946 0.5118
Brugia malayi hypothetical protein 0.0072 0.01 0.01
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0039 0.0029 0.0029
Giardia lamblia Kinase, AGC PKA 0.005 0.0053 0.0559
Entamoeba histolytica cyclin family protein 0.0032 0.0015 0.0155
Trypanosoma cruzi CYC2-like cyclin, putative 0.0076 0.0109 0.0573
Schistosoma mansoni serine/threonine protein kinase 0.005 0.0053 0.0053
Echinococcus granulosus rhodopsin orphan GPCR 0.0072 0.01 0.01
Trypanosoma brucei histone deacetylase 4 0.0134 0.0232 0.1238
Brugia malayi hypothetical protein 0.0031 0.0012 0.0012
Echinococcus granulosus rhodopsin orphan GPCR 0.0072 0.01 0.01
Schistosoma mansoni serine/threonine protein kinase 0.0053 0.0059 0.0059
Echinococcus multilocularis serine threonine protein kinase 0.0113 0.0187 0.0187
Loa Loa (eye worm) TK/FER protein kinase 0.0039 0.003 0.0027
Toxoplasma gondii pyruvate dehydrogenase kinase, putative 0.0043 0.0038 0.0356
Loa Loa (eye worm) hypothetical protein 0.0036 0.0023 0.002
Onchocerca volvulus 0.0031 0.0013 0.0088
Trypanosoma cruzi cdc2-related kinase 3 0.0053 0.0059 0.0299
Echinococcus multilocularis protein kinase c epsilon type 0.0036 0.0023 0.0023
Echinococcus granulosus twitchin 0.0055 0.0064 0.0064
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0889 0.1844 0.1844
Trypanosoma cruzi polo-like protein kinase, putative 0.0105 0.0171 0.091
Schistosoma mansoni neurotransmitter gated ion channel 0.0031 0.0012 0.0012
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.005 0.0053 0.0053
Echinococcus multilocularis 0.0065 0.0085 0.0085
Brugia malayi Serotonin receptor 0.0072 0.01 0.01
Onchocerca volvulus 0.0072 0.01 0.0989
Plasmodium falciparum glycogen synthase kinase 3 0.0058 0.007 0.0698
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0067 0.0089 0.0089
Echinococcus multilocularis tyrosine kinase 0.0039 0.003 0.003
Onchocerca volvulus 0.0036 0.0023 0.0198
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0119 0.02 0.02
Trichomonas vaginalis CMGC family protein kinase 0.0067 0.0089 0.0944
Schistosoma mansoni serine/threonine protein kinase 0.0105 0.0171 0.0171
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0044 0.0041 0.0041
Echinococcus granulosus hemicentin 1 0.0038 0.0028 0.0028
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0072 0.01 0.01
Onchocerca volvulus 0.0039 0.003 0.0264
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0067 0.0089 0.0089
Echinococcus multilocularis serine:threonine protein kinase N2 0.0028 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0044 0.004 0.0037
Schistosoma mansoni opsin-like receptor 0.0072 0.01 0.01
Schistosoma mansoni hypothetical protein 0.0072 0.01 0.01
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0072 0.01 0.01
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0057 0.0068 0.0068
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.005 0.0053 0.0265
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.0196 0.0364 0.0361
Echinococcus granulosus epidermal growth factor receptor 0.0159 0.0286 0.0286
Trypanosoma cruzi rac serine-threonine kinase, putative 0.003 0.0011 0.0036
Trypanosoma brucei polo-like protein kinase 0.0105 0.0171 0.091
Echinococcus multilocularis neuropeptide s receptor 0.0072 0.01 0.01
Echinococcus multilocularis rhodopsin orphan GPCR 0.0072 0.01 0.01
Toxoplasma gondii histone deacetylase HDAC3 0.0468 0.0946 1
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0072 0.01 0.01
Trichomonas vaginalis histone deacetylase, putative 0.0468 0.0946 1
Echinococcus granulosus serotonin receptor 0.0072 0.01 0.01
Echinococcus granulosus serine/threonine protein kinase 0.0032 0.0015 0.0015
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0057 0.0068 0.0068
Echinococcus granulosus 7tm_1 domain containing protein 0.0072 0.01 0.01
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.005 0.0053 0.0053
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0049 0.0052 0.0049
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0037 0.0026 0.0026
Onchocerca volvulus 0.0072 0.01 0.0989
Onchocerca volvulus 0.0076 0.0109 0.1088
Entamoeba histolytica protein kinase domain containing protein 0.0302 0.0591 0.6248
Loa Loa (eye worm) melatonin receptor type 1A 0.0072 0.01 0.0097
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0072 0.01 0.01
Loa Loa (eye worm) hypothetical protein 0.0468 0.0946 0.0943
Schistosoma mansoni cell adhesion molecule 0.0044 0.0041 0.0041
Trichomonas vaginalis CMGC family protein kinase 0.0061 0.0076 0.0805
Echinococcus multilocularis mitogen activated protein kinase 3 0.0061 0.0076 0.0076
Loa Loa (eye worm) hypothetical protein 0.0072 0.01 0.0097
Brugia malayi sulfakinin receptor protein 0.0072 0.01 0.01
Echinococcus granulosus protein kinase shaggy 0.0058 0.007 0.007
Loa Loa (eye worm) histone deacetylase 0.0134 0.0232 0.0229
Brugia malayi serine/threonine-protein kinase plk-2 0.0105 0.0171 0.0171
Schistosoma mansoni neuropeptide receptor 0.0072 0.01 0.01
Echinococcus multilocularis insulin receptor 0.0199 0.0371 0.0371
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0583 0.119 0.119
Trichomonas vaginalis cyclins, putative 0.0076 0.0109 0.1157
Loa Loa (eye worm) hypothetical protein 0.0602 0.1231 0.1229
Trypanosoma brucei cdc2-related kinase 3 0.0053 0.0059 0.0299
Trichomonas vaginalis histone deacetylase, putative 0.0468 0.0946 1
Echinococcus multilocularis activin receptor type 0.0027 0.0004 0.0004
Schistosoma mansoni nAChR subunit 0.0067 0.0089 0.0089
Schistosoma mansoni tyrosine kinase 0.0199 0.0371 0.0371
Brugia malayi RE15519p 0.0072 0.01 0.01
Echinococcus granulosus N chimaerin 0.0027 0.0005 0.0005
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0072 0.01 0.01
Schistosoma mansoni hypothetical protein 0.0072 0.01 0.01
Plasmodium falciparum serine/threonine protein kinase, putative 0.0302 0.0591 0.6231
Echinococcus granulosus tyrosine protein kinase Srms 0.0039 0.003 0.003
Echinococcus granulosus tyrosine protein kinase Lyn 0.0066 0.0087 0.0087
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0031 0.0012 0.0009
Echinococcus granulosus cyclin B3 1 0.0032 0.0015 0.0015
Echinococcus multilocularis roundabout 2 0.0053 0.0059 0.0059
Loa Loa (eye worm) hypothetical protein 0.0076 0.0109 0.0106
Loa Loa (eye worm) hypothetical protein 0.0031 0.0012 0.0009
Echinococcus granulosus tyrosine protein kinase Blk 0.0039 0.003 0.003
Trypanosoma cruzi histone deacetylase, putative 0.0134 0.0232 0.1238
Schistosoma mansoni tyrosine kinase 0.0033 0.0018 0.0018
Schistosoma mansoni cyclins 0.0032 0.0015 0.0015
Trichomonas vaginalis histone deacetylase, putative 0.0468 0.0946 1
Loa Loa (eye worm) hypothetical protein 0.0072 0.01 0.0097
Loa Loa (eye worm) TK/FER protein kinase 0.0039 0.003 0.0027
Giardia lamblia G2/mitotic-specific cyclin B 0.0076 0.0109 0.1157
Onchocerca volvulus 0.0036 0.0023 0.0198
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0057 0.0068 0.0068
Loa Loa (eye worm) STE/STE20/YSK protein kinase 0.0113 0.0187 0.0184
Schistosoma mansoni serine/threonine protein kinase 0.0061 0.0076 0.0076
Trichomonas vaginalis cyclins, putative 0.0076 0.0109 0.1157
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0067 0.0089 0.0086
Echinococcus multilocularis neuroglian 0.0046 0.0045 0.0045
Loa Loa (eye worm) G-protein coupled receptor 0.0072 0.01 0.0097
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0057 0.0068 0.0068
Loa Loa (eye worm) hypothetical protein 0.0031 0.0012 0.0009
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0072 0.01 0.01
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0137 0.024 0.1281
Echinococcus granulosus neuropeptide receptor A26 0.0072 0.01 0.01
Loa Loa (eye worm) hypothetical protein 0.0072 0.01 0.0097
Onchocerca volvulus 0.0072 0.01 0.0989
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.005 0.0053 0.0053
Brugia malayi Hr1 repeat family protein 0.0028 0.0007 0.0007
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0057 0.0068 0.0068
Brugia malayi larval opioid receptor 0.0072 0.01 0.01
Loa Loa (eye worm) hypothetical protein 0.0073 0.0103 0.01
Schistosoma mansoni serine/threonine protein kinase 0.005 0.0053 0.0053
Entamoeba histolytica hypothetical protein 0.0036 0.0023 0.0248
Trypanosoma cruzi cdc2-related kinase 3 0.0053 0.0059 0.0299
Loa Loa (eye worm) hypothetical protein 0.0072 0.01 0.0097
Loa Loa (eye worm) TK/FER protein kinase 0.0039 0.003 0.0027
Brugia malayi Protein kinase domain containing protein 0.048 0.097 0.097
Loa Loa (eye worm) hypothetical protein 0.0067 0.0089 0.0086
Entamoeba histolytica PH domain containing protein kinase, putative 0.0032 0.0015 0.016
Brugia malayi hypothetical protein 0.0037 0.0026 0.0026
Trypanosoma cruzi cyclin, putative 0.0076 0.0109 0.0573
Loa Loa (eye worm) hypothetical protein 0.0031 0.0012 0.0009
Schistosoma mansoni pyruvate dehydrogenase 0.0115 0.0192 0.0192
Brugia malayi Protein kinase domain containing protein 0.0039 0.003 0.003
Loa Loa (eye worm) hypothetical protein 0.0067 0.0089 0.0086
Schistosoma mansoni growth factor receptor-bound protein 0.0039 0.003 0.003
Trypanosoma cruzi Protein kinase B 0.0032 0.0015 0.006
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0199 0.0371 0.0371
Schistosoma mansoni pyruvate dehydrogenase 0.0115 0.0192 0.0192
Loa Loa (eye worm) hypothetical protein 0.0067 0.0089 0.0086
Schistosoma mansoni serine/threonine protein kinase 0.0028 0.0007 0.0007
Brugia malayi AKH receptor 0.0072 0.01 0.01
Schistosoma mansoni serine/threonine protein kinase 0.0076 0.0109 0.0109
Schistosoma mansoni neuropeptide receptor 0.0072 0.01 0.01
Echinococcus granulosus tyrosine protein kinase Fyn 0.0057 0.0068 0.0068
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0067 0.0089 0.0086
Brugia malayi Dopamine receptor protein 1 0.0072 0.01 0.01
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0067 0.0089 0.0089
Giardia lamblia Histone deacetylase 0.0468 0.0946 1
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.005 0.0053 0.0053
Brugia malayi hypothetical protein 0.0031 0.0012 0.0012
Loa Loa (eye worm) AGC/PKA protein kinase 0.005 0.0053 0.005
Echinococcus multilocularis fmrfamide receptor 0.0072 0.01 0.01
Plasmodium falciparum protein kinase 5 0.0053 0.0059 0.0584
Plasmodium vivax histone deacetylase, putative 0.0134 0.0232 0.2364
Trichomonas vaginalis CMGC family protein kinase 0.0053 0.0059 0.0625
Plasmodium vivax histone deacetylase, putative 0.0134 0.0232 0.2364
Toxoplasma gondii histone deacetylase HDAC2 0.0468 0.0946 1
Loa Loa (eye worm) hypothetical protein 0.0037 0.0026 0.0023
Giardia lamblia Kinase, CDC7 0.0067 0.0089 0.0944
Schistosoma mansoni biogenic amine receptor 0.0072 0.01 0.01
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0067 0.0089 0.0089
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0072 0.01 0.01
Schistosoma mansoni serine/threonine protein kinase 0.018 0.033 0.033
Trichomonas vaginalis AGC family protein kinase 0.0028 0.0007 0.0074
Leishmania major developmentally regulated phosphoprotein-like protein 0.0122 0.0207 0.1101
Echinococcus multilocularis serine:threonine protein kinase NIM1 0.0093 0.0145 0.0145
Loa Loa (eye worm) hypothetical protein 0.0036 0.0023 0.002
Plasmodium falciparum protein kinase, putative 0.0113 0.0187 0.1946
Loa Loa (eye worm) hypothetical protein 0.0036 0.0023 0.002
Loa Loa (eye worm) hypothetical protein 0.0036 0.0023 0.002
Echinococcus multilocularis serine:threonine protein kinase 38 0.0028 0.0007 0.0007
Echinococcus granulosus biogenic amine 5HT receptor 0.0072 0.01 0.01
Echinococcus granulosus tm gpcr rhodopsin 0.0072 0.01 0.01
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0072 0.01 0.01
Echinococcus granulosus dro:myosuppressin receptor 0.0072 0.01 0.01
Onchocerca volvulus 0.0067 0.0089 0.0879
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0027 0.0005 0.0005
Loa Loa (eye worm) TK/EGFR protein kinase 0.023 0.0436 0.0433
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0057 0.0068 0.0068
Brugia malayi Fibronectin type III domain containing protein 0.0037 0.0026 0.0026
Echinococcus multilocularis epidermal growth factor receptor 0.0159 0.0286 0.0286
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0072 0.01 0.01
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0053 0.0059 0.0059
Onchocerca volvulus 0.0039 0.003 0.0264
Schistosoma mansoni growth factor receptor-bound protein 0.0039 0.003 0.003
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0028 0.0007 0.0007
Trichomonas vaginalis AGC family protein kinase 0.005 0.0053 0.0559
Schistosoma mansoni tyrosine kinase 0.0057 0.0068 0.0068
Echinococcus granulosus nAChR subunit 0.0036 0.0023 0.0023
Loa Loa (eye worm) CDC7 protein kinase 0.0067 0.0089 0.0086
Trypanosoma brucei histone deacetylase 3 0.0134 0.0232 0.1238
Loa Loa (eye worm) hypothetical protein 0.0072 0.01 0.0097
Trypanosoma brucei protein kinase, putative 0.0061 0.0076 0.0392
Loa Loa (eye worm) hypothetical protein 0.0076 0.0109 0.0106
Echinococcus multilocularis histone deacetylase 3 0.0468 0.0946 0.0946
Echinococcus granulosus neuropeptide FF receptor 2 0.0072 0.01 0.01
Plasmodium vivax glycogen synthase kinase 3, putative 0.0058 0.007 0.0632
Brugia malayi Protein kinase c protein 2 0.0057 0.0068 0.0068
Echinococcus granulosus histone deacetylase 3 0.0468 0.0946 0.0946
Schistosoma mansoni tyrosine kinase 0.0141 0.0248 0.0248
Brugia malayi neuropeptide F receptor 0.0072 0.01 0.01
Echinococcus multilocularis neuropeptide receptor 0.0072 0.01 0.01
Brugia malayi hypothetical protein 0.0072 0.01 0.01
Onchocerca volvulus Serine\/threonine kinase homolog 0.0105 0.0171 0.173
Loa Loa (eye worm) hypothetical protein 0.004 0.0033 0.003
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0057 0.0068 0.0068
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0028 0.0007 0.0004
Echinococcus granulosus g protein coupled receptor 0.0072 0.01 0.01
Loa Loa (eye worm) AGC/PKN protein kinase 0.0028 0.0007 0.0004
Echinococcus multilocularis histone deacetylase 1 0.0468 0.0946 0.0946
Loa Loa (eye worm) hypothetical protein 0.0039 0.003 0.0027
Schistosoma mansoni nAChR subunit 0.0067 0.0089 0.0089
Entamoeba histolytica SH2-protein kinase domain containing protein 0.003 0.0011 0.0115
Echinococcus multilocularis cyclin dependent kinase 5 0.0053 0.0059 0.0059
Echinococcus multilocularis rhodopsin orphan GPCR 0.0072 0.01 0.01
Echinococcus granulosus serine:threonine protein kinase N2 0.0028 0.0007 0.0007
Entamoeba histolytica protein kinase, putative 0.0027 0.0004 0.0047
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0072 0.01 0.01
Echinococcus granulosus nAChR subunit 0.0067 0.0089 0.0089
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0032 0.0015 0.006
Loa Loa (eye worm) hypothetical protein 0.0072 0.01 0.0097
Leishmania major CYC2-like cyclin, putative,cyclin 6, putative 0.0076 0.0109 0.0573
Schistosoma mansoni biogenic amine receptor 0.0072 0.01 0.01
Loa Loa (eye worm) hypothetical protein 0.0072 0.01 0.0097
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0072 0.01 0.01
Plasmodium vivax histone deacetylase 2, putative 0.0134 0.0232 0.2364
Brugia malayi Tyrosine-protein kinase abl-1 0.013 0.0225 0.0225
Echinococcus granulosus protein kinase c epsilon type 0.0036 0.0023 0.0023
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0072 0.01 0.0097
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0067 0.0089 0.0089
Schistosoma mansoni nephrin 0.0046 0.0045 0.0045
Trypanosoma brucei rac serine-threonine kinase, putative 0.0051 0.0056 0.0284
Echinococcus granulosus alpha 1A adrenergic receptor 0.0072 0.01 0.01
Echinococcus multilocularis dro:myosuppressin receptor 0.0072 0.01 0.01
Echinococcus multilocularis rhodopsin orphan GPCR 0.0072 0.01 0.01
Brugia malayi Protein kinase domain containing protein 0.0028 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0037 0.0027 0.0024
Loa Loa (eye worm) TK/FER protein kinase 0.0039 0.003 0.0027
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0036 0.0023 0.002
Brugia malayi cell division control protein 2 homolog 0.0053 0.0059 0.0059
Schistosoma mansoni vav2 0.0029 0.0009 0.0009
Echinococcus multilocularis N chimaerin 0.0027 0.0005 0.0005
Brugia malayi Protein kinase domain containing protein 0.0091 0.0141 0.0141
Onchocerca volvulus 0.048 0.097 1
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0072 0.01 0.0097
Onchocerca volvulus Histone deacetylase 10 homolog 0.0134 0.0232 0.2354
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0067 0.0089 0.0086
Entamoeba histolytica protein kinase, putative 0.0058 0.007 0.0738
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0027 0.0004 0.0004
Brugia malayi hypothetical protein 0.0029 0.001 0.001
Echinococcus granulosus mitogen activated protein kinase 3 0.0061 0.0076 0.0076
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.005 0.0053 0.0518
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0061 0.0076 0.0765
Entamoeba histolytica protein kinase, putative 0.0028 0.0007 0.0074
Onchocerca volvulus 0.0058 0.007 0.0677
Echinococcus granulosus peptide allatostatin:somatostatin 0.0072 0.01 0.01
Entamoeba histolytica cyclin family protein 0.0032 0.0015 0.0155
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0067 0.0089 0.0086
Echinococcus granulosus tyrosine kinase 0.0039 0.003 0.003
Echinococcus multilocularis histone deacetylase 6 0.0134 0.0232 0.0232
Echinococcus multilocularis histone deacetylase 0.0134 0.0232 0.0232
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0072 0.01 0.0097
Loa Loa (eye worm) IKK protein kinase 0.048 0.097 0.0967
Echinococcus granulosus sex peptide receptor 0.0072 0.01 0.01
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0036 0.0024 0.0249
Echinococcus granulosus somatostatin receptor 0.0072 0.01 0.01
Trypanosoma brucei developmentally regulated phosphoprotein 0.0122 0.0207 0.1101
Echinococcus multilocularis tyrosine protein kinase Abl 0.0138 0.024 0.024
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0067 0.0089 0.0089
Brugia malayi protein kinase C II. 0.0036 0.0023 0.0023
Trichomonas vaginalis STE family protein kinase 0.0113 0.0187 0.1981
Schistosoma mansoni nAChR subunit 0.0067 0.0089 0.0089
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0067 0.0089 0.0086
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0067 0.0089 0.0089
Echinococcus multilocularis NCK adaptor protein 0.0039 0.003 0.003
Schistosoma mansoni tyrosine kinase 0.0199 0.0371 0.0371
Onchocerca volvulus 0.0072 0.01 0.0989
Loa Loa (eye worm) hypothetical protein 0.0031 0.0012 0.0009
Loa Loa (eye worm) hypothetical protein 0.0067 0.0089 0.0086
Echinococcus granulosus fibroblast growth factor receptor 4 0.0119 0.02 0.02
Brugia malayi MAP kinase sur-1 0.0061 0.0076 0.0076
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0057 0.0068 0.0068
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.0031 0.0012 0.0012
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0072 0.01 0.01
Loa Loa (eye worm) hypothetical protein 0.0067 0.0089 0.0086
Onchocerca volvulus 0.0072 0.01 0.0989
Schistosoma mansoni serine/threonine kinase 0.0028 0.0007 0.0007
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.005 0.0053 0.0451
Brugia malayi Sex muscle abnormal protein 5 0.0039 0.003 0.003
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0072 0.01 0.01
Loa Loa (eye worm) hypothetical protein 0.0039 0.003 0.0027
Echinococcus multilocularis tyrosine protein kinase Srms 0.0039 0.003 0.003
Onchocerca volvulus 0.0067 0.0089 0.0877
Brugia malayi kinase, mitochondrial precursor 0.0122 0.0207 0.0207
Trichomonas vaginalis cyclin B, putative 0.0076 0.0109 0.1157
Leishmania major pyruvate dehydrogenase (lipoamide) kinase, putative 0.0043 0.0038 0.0182
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0067 0.0089 0.0089
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0061 0.0076 0.0392
Echinococcus granulosus protein kinase c iota type 0.0034 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0031 0.0012 0.0009
Brugia malayi hypothetical protein 0.0072 0.01 0.01
Schistosoma mansoni protein kinase 0.0027 0.0004 0.0004
Schistosoma mansoni tyrosine kinase 0.0235 0.0448 0.0448
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0067 0.0089 0.0089
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0072 0.01 0.01
Echinococcus multilocularis neuropeptide Y receptor 0.0072 0.01 0.01
Schistosoma mansoni nAChR subunit 0.0067 0.0089 0.0089
Brugia malayi hypothetical protein 0.0031 0.0012 0.0012
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0039 0.003 0.0027
Echinococcus granulosus tyrosine protein kinase shark 0.0256 0.0493 0.0493
Trichomonas vaginalis cyclins, putative 0.0076 0.0109 0.1157
Brugia malayi Cyclin, N-terminal domain containing protein 0.0032 0.0015 0.0015
Echinococcus granulosus histone deacetylase 1 0.0468 0.0946 0.0946
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0028 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0075 0.0107 0.0104
Trichomonas vaginalis CMGC family protein kinase 0.0053 0.0059 0.0625
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0067 0.0089 0.0089
Trypanosoma cruzi histone deacetylase, putative 0.0134 0.0232 0.1238
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0072 0.01 0.01
Echinococcus multilocularis neuropeptide receptor A26 0.0072 0.01 0.01
Trichomonas vaginalis AGC family protein kinase 0.0028 0.0007 0.0074
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0053 0.0059 0.0056
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.005 0.0053 0.0053
Schistosoma mansoni amine GPCR 0.0072 0.01 0.01
Onchocerca volvulus 0.0039 0.003 0.0264
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0119 0.02 0.02
Brugia malayi Furin-like cysteine rich region family protein 0.023 0.0436 0.0436
Echinococcus granulosus tyrosine protein kinase Src64B 0.0057 0.0068 0.0068
Schistosoma mansoni alpha-1 adrenergic receptor 0.0072 0.01 0.01
Loa Loa (eye worm) hypothetical protein 0.0072 0.01 0.0097
Onchocerca volvulus Netrin receptor homolog 0.0031 0.0013 0.0088
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0302 0.0591 0.0591
Schistosoma mansoni tyrosine kinase 0.0119 0.02 0.02
Brugia malayi Immunoglobulin I-set domain containing protein 0.0127 0.0218 0.0218
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0067 0.0089 0.0089
Echinococcus multilocularis protein kinase shaggy 0.0058 0.007 0.007
Loa Loa (eye worm) TK protein kinase 0.0039 0.003 0.0027
Entamoeba histolytica protein kinase domain containing protein 0.0058 0.007 0.0738
Loa Loa (eye worm) hypothetical protein 0.0031 0.0012 0.0009
Schistosoma mansoni kinase 0.0058 0.007 0.007
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0072 0.01 0.01
Echinococcus granulosus cyclins 0.0032 0.0015 0.0015
Echinococcus granulosus tyrosine protein kinase ABL1 0.025 0.048 0.048
Loa Loa (eye worm) hypothetical protein 0.0072 0.01 0.0097
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0067 0.0089 0.0089
Echinococcus granulosus histone deacetylase 6 0.0134 0.0232 0.0232
Brugia malayi hypothetical protein 0.0072 0.01 0.01
Loa Loa (eye worm) hypothetical protein 0.0067 0.0089 0.0086
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.0193 0.0358 0.0355
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0028 0.0007 0.0004
Onchocerca volvulus Tyrosine kinase homolog 0.0367 0.0729 0.7502
Trichomonas vaginalis CMGC family protein kinase 0.0058 0.007 0.0738
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0039 0.003 0.0027
Echinococcus granulosus mitogen activated protein kinase 11 0.0137 0.024 0.024
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0067 0.0089 0.0089
Loa Loa (eye worm) hypothetical protein 0.0031 0.0012 0.0009
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0057 0.0068 0.0068
Echinococcus multilocularis cyclin B3 1 0.0032 0.0015 0.0015
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0137 0.024 0.1281
Echinococcus granulosus tyrosine protein kinase Src42A 0.0057 0.0068 0.0068
Loa Loa (eye worm) hypothetical protein 0.0072 0.01 0.0097
Onchocerca volvulus 0.0072 0.01 0.0989
Giardia lamblia Kinase, CMGC GSK 0.0058 0.007 0.0738
Trichomonas vaginalis CMGC family protein kinase 0.0058 0.007 0.0738

Activities

Activity type Activity value Assay description Source Reference
Inhibition (binding) = 330 % Ki value determined against Opioid receptor kappa 1 using [3H]U69, 593 at the Kd concentration 0.95 nM ChEMBL. 11150174
Inhibition (binding) = 330 % Ki value determined against Opioid receptor kappa 1 using [3H]U69, 593 at the Kd concentration 0.95 nM ChEMBL. 11150174
Inhibition (binding) = 3600 % Ki value determined against Opioid receptor mu 1 using [3H]-DAMGO at the Kd concentration 0.57 nM ChEMBL. 11150174
Inhibition (binding) = 3600 % Ki value determined against Opioid receptor mu 1 using [3H]-DAMGO at the Kd concentration 0.57 nM ChEMBL. 11150174
Inhibition (binding) > 10000 % Ki value determined against Opioid receptor delta 1 using [3H]-DPDPE at the Kd concentration 2.1 nM . ChEMBL. 11150174
Inhibition (binding) > 10000 % Ki value determined against Opioid receptor delta 1 using [3H]-DPDPE at the Kd concentration 2.1 nM . ChEMBL. 11150174
Ki (binding) = 18 nM Ki value determined against Sigma opioid receptor type 1 ChEMBL. 11150174
Ki (binding) = 18 nM Ki value determined against Sigma opioid receptor type 1 ChEMBL. 11150174
Ki (binding) = 3500 nM Ki value determined against Sigma opioid receptor type 2 ChEMBL. 11150174
Ki (binding) = 3500 nM Ki value determined against Sigma opioid receptor type 2 ChEMBL. 11150174

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.