TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 298.335 | Formula: C21H14O2
H donors: 1 H acceptors: 2 LogP: 4.39 Rotable bonds: 2
Rule of 5 violations (Lipinski): 1
SMILES: Oc1ccc2c(c1)C(=O)C(=C2c1ccccc1)c1ccccc1
InChi: 1S/C21H14O2/c22-16-11-12-17-18(13-16)21(23)20(15-9-5-2-6-10-15)19(17)14-7-3-1-4-8-14/h1-13,22H
InChiKey: PSIWCAPXPBELTO-UHFFFAOYSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Echinococcus granulosus	GPCR family 2	0.0032	0.0137	0.0137
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0027	0.0068	0.0041
Toxoplasma gondii	PAN domain-containing protein	0.0092	0.0907	0.2294
Giardia lamblia	Kinase, CDC7	0.0432	0.5276	1
Loa Loa (eye worm)	hypothetical protein	0.0101	0.1029	0.1058
Loa Loa (eye worm)	tubulin beta-1 chain	0.0293	0.3492	0.359
Loa Loa (eye worm)	melatonin receptor type 1A	0.0168	0.1887	0.194
Trichomonas vaginalis	CMGC family protein kinase	0.0432	0.5276	1
Echinococcus multilocularis	tubulin beta 1 chain	0.0293	0.3492	0.3492
Echinococcus multilocularis	lamin	0.0027	0.0078	0.0078
Onchocerca volvulus		0.0092	0.0907	0.0933
Loa Loa (eye worm)	hypothetical protein	0.0168	0.1887	0.194
Brugia malayi	calcium-independent alpha-latrotoxin receptor 2, putative	0.0032	0.0137	0.0141
Echinococcus multilocularis	protein jagged 1	0.005	0.0368	0.0368
Echinococcus multilocularis	G protein coupled 5 hydroxytryptamine receptor	0.0168	0.1887	0.1887
Schistosoma mansoni	neuropeptide F-like receptor	0.0168	0.1887	0.1887
Schistosoma mansoni	peptide (allatostatin)-like receptor	0.0168	0.1887	0.1887
Brugia malayi	GnHR receptor homolog	0.0168	0.1887	0.194
Schistosoma mansoni	hypothetical protein	0.0172	0.1942	0.1942
Trypanosoma brucei	beta tubulin	0.0293	0.3492	0.9944
Brugia malayi	SRC-1	0.0053	0.0406	0.0418
Loa Loa (eye worm)	hypothetical protein	0.0109	0.1129	0.1161
Loa Loa (eye worm)	PAN domain-containing protein	0.0092	0.0907	0.0933
Trichomonas vaginalis	tubulin alpha chain, putative	0.0293	0.3492	0.6574
Loa Loa (eye worm)	hypothetical protein	0.005	0.0368	0.0378
Echinococcus multilocularis	dnaJ subfamily B	0.0799	1	1
Echinococcus multilocularis	Tubulin beta 2C chain	0.0293	0.3492	0.3492
Schistosoma mansoni	thyrotropin-releasing hormone receptor	0.0168	0.1887	0.1887
Loa Loa (eye worm)	hypothetical protein	0.005	0.0368	0.0378
Echinococcus multilocularis	neuropeptide receptor	0.0168	0.1887	0.1887
Loa Loa (eye worm)	hypothetical protein	0.0168	0.1887	0.194
Onchocerca volvulus		0.005	0.0368	0.0378
Loa Loa (eye worm)	hypothetical protein	0.0168	0.1887	0.194
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	0.0091	0.0897	0.0897
Brugia malayi	Trypsin-like protease protein 5	0.0109	0.1129	0.1161
Echinococcus multilocularis	neuropeptides capa receptor	0.0168	0.1887	0.1887
Trichomonas vaginalis	CMGC family protein kinase	0.0432	0.5276	1
Echinococcus granulosus	pyroglutamylated rfamide peptide receptor	0.0168	0.1887	0.1887
Loa Loa (eye worm)	hypothetical protein	0.0168	0.1887	0.194
Schistosoma mansoni	neuropeptide receptor	0.0168	0.1887	0.1887
Onchocerca volvulus		0.0027	0.0068	0.007
Loa Loa (eye worm)	intermediate filament protein	0.0027	0.0078	0.008
Onchocerca volvulus		0.005	0.0368	0.0378
Loa Loa (eye worm)	hypothetical protein	0.005	0.0368	0.0378
Schistosoma mansoni	cercarial elastase (S01 family)	0.0109	0.1129	0.1129
Brugia malayi	PAN domain containing protein	0.0092	0.0907	0.0933
Loa Loa (eye worm)	hypothetical protein	0.0092	0.0907	0.0933
Loa Loa (eye worm)	follicle stimulating hormone receptor	0.0168	0.1887	0.194
Brugia malayi	Cadherin domain containing protein	0.005	0.0368	0.0378
Schistosoma mansoni	tyrosine kinase	0.0053	0.0406	0.0406
Loa Loa (eye worm)	tubulin beta chain	0.0293	0.3492	0.359
Brugia malayi	G-protein coupled receptor	0.0168	0.1887	0.194
Onchocerca volvulus		0.0109	0.1129	0.1161
Toxoplasma gondii	kringle domain-containing protein	0.0315	0.3774	1
Leishmania major	beta tubulin	0.0293	0.3492	0.9242
Trypanosoma brucei	beta tubulin	0.0293	0.3492	0.9944
Leishmania major	beta tubulin	0.0293	0.3492	0.9242
Onchocerca volvulus		0.0027	0.0068	0.007
Onchocerca volvulus		0.0168	0.1887	0.194
Schistosoma mansoni	lamin	0.0027	0.0078	0.0078
Toxoplasma gondii	1,3(4)-beta-glucanase	0.0092	0.0907	0.2294
Schistosoma mansoni	notch	0.005	0.0368	0.0368
Leishmania major	cathepsin L-like protease	0.0027	0.0068	0.0038
Echinococcus granulosus	protein jagged 2	0.005	0.0368	0.0368
Trypanosoma cruzi	mitochondrial DNA polymerase beta-PAK, putative	0.0139	0.1517	0.3934
Giardia lamblia	Beta tubulin	0.0293	0.3492	0.6367
Loa Loa (eye worm)	hypothetical protein	0.005	0.0368	0.0378
Echinococcus multilocularis	cathepsin b	0.0142	0.1556	0.1556
Schistosoma mansoni	amine GPCR	0.0168	0.1887	0.1887
Trypanosoma cruzi	mitochondrial DNA polymerase beta-PAK, putative	0.0041	0.0258	0.0549
Trypanosoma brucei	cysteine peptidase C (CPC)	0.005	0.0365	0.0901
Onchocerca volvulus		0.0168	0.1887	0.194
Loa Loa (eye worm)	hypothetical protein	0.0168	0.1887	0.194
Leishmania major	cathepsin L-like protease	0.0027	0.0068	0.0038
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	0.0091	0.0897	0.0897
Toxoplasma gondii	microneme protein MIC17C	0.0092	0.0907	0.2294
Loa Loa (eye worm)	hypothetical protein	0.0168	0.1887	0.194
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0053	0.0406	0.0406
Toxoplasma gondii	subtilisin SUB12	0.0092	0.0907	0.2294
Brugia malayi	Latrophilin receptor protein 2	0.0032	0.0137	0.0141
Echinococcus multilocularis	GPCR, family 2	0.0032	0.0137	0.0137
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0053	0.0406	0.0406
Echinococcus multilocularis	tyrosine protein kinase Src42A	0.0053	0.0406	0.0406
Echinococcus granulosus	protein jagged 2	0.005	0.0368	0.0368
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	0.0091	0.0897	0.0897
Brugia malayi	Dopamine receptor	0.0168	0.1887	0.194
Loa Loa (eye worm)	hypothetical protein	0.005	0.0368	0.0378
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0027	0.0068	0.0041
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0168	0.1887	0.1887
Echinococcus granulosus	tyrosine protein kinase HCK	0.0033	0.0144	0.0144
Brugia malayi	cathepsin B-like cysteine proteinase	0.0142	0.1556	0.16
Loa Loa (eye worm)	hypothetical protein	0.0168	0.1887	0.194
Loa Loa (eye worm)	hypothetical protein	0.0168	0.1887	0.194
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0168	0.1887	0.1887
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0027	0.0068	0.0041
Echinococcus granulosus	cathepsin b	0.0142	0.1556	0.1556
Echinococcus granulosus	neurogenic locus notch protein 4	0.005	0.0368	0.0368
Echinococcus granulosus	neuropeptide s receptor	0.0168	0.1887	0.1887
Brugia malayi	PAN domain containing protein	0.0092	0.0907	0.0933
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0168	0.1887	0.1887
Echinococcus multilocularis	cadherin EGF LAG seven pass G type receptor	0.0032	0.0137	0.0137
Loa Loa (eye worm)	hypothetical protein	0.0168	0.1887	0.194
Loa Loa (eye worm)	hypothetical protein	0.0168	0.1887	0.194
Echinococcus multilocularis	tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase	0.0053	0.0406	0.0406
Echinococcus granulosus	neuropeptide Y receptor	0.0168	0.1887	0.1887
Loa Loa (eye worm)	matrixin family protein	0.0047	0.0332	0.0341
Onchocerca volvulus		0.0027	0.0068	0.007
Loa Loa (eye worm)	hypothetical protein	0.0101	0.1029	0.1058
Toxoplasma gondii	microneme protein MIC17B	0.0092	0.0907	0.2294
Leishmania major	cathepsin L-like protease	0.0027	0.0068	0.0038
Brugia malayi	Serotonin/octopamine receptor family protein 7	0.0168	0.1887	0.194
Schistosoma mansoni	hypothetical protein	0.005	0.0368	0.0368
Plasmodium vivax	cysteine repeat modular protein 1, putative	0.0315	0.3774	1
Schistosoma mansoni	slit	0.005	0.0368	0.0368
Loa Loa (eye worm)	hypothetical protein	0.0032	0.0137	0.0141
Echinococcus granulosus	tyrosine protein kinase Fyn	0.0053	0.0406	0.0406
Loa Loa (eye worm)	hypothetical protein	0.0168	0.1887	0.194
Onchocerca volvulus		0.0027	0.0068	0.007
Trypanosoma cruzi	cysteine peptidase, putative	0.0027	0.0068	0.0038
Echinococcus multilocularis	g-protein coupled receptor	0.0168	0.1887	0.1887
Schistosoma mansoni	subfamily S1A unassigned peptidase (S01 family)	0.0778	0.9726	0.9726
Loa Loa (eye worm)	hypothetical protein	0.005	0.0368	0.0378
Toxoplasma gondii	histone lysine methyltransferase SET1	0.0053	0.0411	0.0961
Brugia malayi	larval opioid receptor	0.0168	0.1887	0.194
Echinococcus multilocularis	beta tubulin	0.0293	0.3492	0.3492
Echinococcus granulosus	neural cadherin	0.005	0.0368	0.0368
Onchocerca volvulus		0.0109	0.1129	0.1161
Echinococcus granulosus	rhodopsin orphan GPCR	0.0168	0.1887	0.1887
Echinococcus granulosus	Tubulin beta 2C chain	0.0293	0.3492	0.3492
Onchocerca volvulus		0.0092	0.0907	0.0933
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0027	0.0068	0.0041
Schistosoma mansoni	hypothetical protein	0.0799	1	1
Echinococcus multilocularis	proto oncogene tyrosine protein kinase LCK	0.0053	0.0406	0.0406
Trypanosoma brucei	mitochondrial DNA polymerase beta-PAK	0.0139	0.1517	0.4233
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0027	0.0068	0.0041
Brugia malayi	G protein-coupled receptor F59B2.13	0.0168	0.1887	0.194
Echinococcus multilocularis	cysteine protease	0.0027	0.0068	0.0068
Schistosoma mansoni	cpg binding protein	0.003	0.0108	0.0108
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0168	0.1887	0.1887
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0168	0.1887	0.1887
Echinococcus granulosus	neuropeptide receptor	0.0168	0.1887	0.1887
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0168	0.1887	0.1887
Loa Loa (eye worm)	TK/ROR protein kinase	0.0319	0.3825	0.3932
Loa Loa (eye worm)	hypothetical protein	0.0092	0.0907	0.0933
Echinococcus multilocularis	protein jagged 1	0.005	0.0368	0.0368
Echinococcus multilocularis	alpha 1A adrenergic receptor	0.0168	0.1887	0.1887
Leishmania major	beta tubulin	0.0293	0.3492	0.9242
Brugia malayi	Cathepsin L-like precursor	0.0027	0.0068	0.007
Loa Loa (eye worm)	hypothetical protein	0.0168	0.1887	0.194
Schistosoma mansoni	peptide (FMRFamide/somatostatin)-like receptor	0.0168	0.1887	0.1887
Brugia malayi	EGF-like domain containing protein	0.005	0.0368	0.0378
Toxoplasma gondii	beta tubulin	0.0293	0.3492	0.9242
Echinococcus granulosus	beta tubulin	0.0293	0.3492	0.3492
Onchocerca volvulus		0.0668	0.8322	0.8557
Trichomonas vaginalis	CMGC family protein kinase	0.0432	0.5276	1
Brugia malayi	Calcium binding EGF domain containing protein	0.005	0.0368	0.0378
Echinococcus multilocularis	tubulin, beta 4A class IVa	0.0293	0.3492	0.3492
Brugia malayi	Fibulin-1 precursor	0.0101	0.1029	0.1058
Brugia malayi	hypothetical protein	0.0168	0.1887	0.194
Mycobacterium ulcerans	hypothetical protein	0.0155	0.172	0.5227
Onchocerca volvulus		0.0168	0.1887	0.194
Trypanosoma cruzi	mitochondrial DNA polymerase beta, putative	0.0294	0.3512	0.9295
Trypanosoma cruzi	beta tubulin, putative	0.0293	0.3492	0.9242
Echinococcus multilocularis	cathepsin L cysteine protease	0.0027	0.0068	0.0068
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0168	0.1887	0.1887
Onchocerca volvulus		0.0168	0.1887	0.194
Loa Loa (eye worm)	hypothetical protein	0.0092	0.0907	0.0933
Loa Loa (eye worm)	hypothetical protein	0.0168	0.1887	0.194
Echinococcus granulosus	beta tubulin	0.0293	0.3492	0.3492
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0168	0.1887	0.1887
Echinococcus multilocularis	growth hormone secretagogue receptor type 1	0.0168	0.1887	0.1887
Loa Loa (eye worm)	matrixin family protein	0.0051	0.0386	0.0397
Brugia malayi	protein-tyrosine kinase	0.0043	0.0277	0.0284
Schistosoma mansoni	hypothetical protein	0.0172	0.1942	0.1942
Echinococcus granulosus	fmrfamide receptor	0.0168	0.1887	0.1887
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	0.0091	0.0897	0.0897
Leishmania major	beta tubulin	0.0293	0.3492	0.9242
Loa Loa (eye worm)	low-density lipoprotein receptor repeat class B containing protein	0.0101	0.1029	0.1058
Brugia malayi	hypothetical protein	0.0168	0.1887	0.194
Echinococcus multilocularis	neuropeptide receptor	0.0168	0.1887	0.1887
Schistosoma mansoni	opsin-like receptor	0.0168	0.1887	0.1887
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0168	0.1887	0.1887
Loa Loa (eye worm)	TK protein kinase	0.0043	0.0277	0.0284
Schistosoma mansoni	intermediate filament proteins	0.0027	0.0078	0.0078
Echinococcus multilocularis	fmrfamide receptor	0.0168	0.1887	0.1887
Brugia malayi	Cathepsin L-like precursor	0.0027	0.0068	0.007
Echinococcus granulosus	Tubulin beta 2C chain	0.0293	0.3492	0.3492
Echinococcus granulosus	tm gpcr rhodopsin	0.0168	0.1887	0.1887
Schistosoma mansoni	myosin xvIII	0.0168	0.1887	0.1887
Plasmodium vivax	tubulin beta chain, putative	0.0293	0.3492	0.9242
Brugia malayi	Cathepsin L-like precursor	0.0027	0.0068	0.007
Echinococcus granulosus	tubulin beta 4A class IVa	0.0293	0.3492	0.3492
Echinococcus multilocularis	biogenic amine (5HT) receptor	0.0168	0.1887	0.1887
Loa Loa (eye worm)	hypothetical protein	0.005	0.0368	0.0378
Echinococcus multilocularis	peptide (allatostatin:somatostatin)	0.0168	0.1887	0.1887
Echinococcus granulosus	tm gpcr rhodopsin	0.0168	0.1887	0.1887
Loa Loa (eye worm)	hypothetical protein	0.0168	0.1887	0.194
Echinococcus granulosus	g-protein coupled receptor	0.0168	0.1887	0.1887
Echinococcus granulosus	serotonin receptor	0.0168	0.1887	0.1887
Echinococcus granulosus	cpg binding protein	0.003	0.0108	0.0108
Echinococcus granulosus	tyrosine protein kinase Src64B	0.0053	0.0406	0.0406
Schistosoma mansoni	hypothetical protein	0.0032	0.0137	0.0137
Schistosoma mansoni	amine GPCR	0.0168	0.1887	0.1887
Trichomonas vaginalis	tubulin beta chain, putative	0.0293	0.3492	0.6574
Onchocerca volvulus		0.0027	0.0078	0.008
Loa Loa (eye worm)	hypothetical protein	0.0168	0.1887	0.194
Loa Loa (eye worm)	Notch2	0.005	0.0368	0.0378
Echinococcus multilocularis	fat cadherin tumor suppressor	0.005	0.0368	0.0368
Leishmania major	beta tubulin	0.0293	0.3492	0.9242
Brugia malayi	latrophilin 2 splice variant baaae	0.0069	0.0616	0.0633
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0027	0.0068	0.0041
Loa Loa (eye worm)	notch protein	0.005	0.0368	0.0378
Brugia malayi	follicle stimulating hormone receptor	0.0168	0.1887	0.194
Entamoeba histolytica	hypothetical protein	0.0037	0.02	0.0387
Echinococcus multilocularis	cathepsin l cysteine peptidase	0.0027	0.0068	0.0068
Echinococcus granulosus	biogenic amine 5HT receptor	0.0168	0.1887	0.1887
Trypanosoma brucei	DNA polymerase beta thumb, putative	0.0041	0.0258	0.0591
Mycobacterium tuberculosis	Probable oxidoreductase	0.0273	0.3237	1
Brugia malayi	neuropeptide F receptor	0.0168	0.1887	0.194
Loa Loa (eye worm)	hypothetical protein	0.0168	0.1887	0.194
Toxoplasma gondii	beta-tubulin, putative	0.0293	0.3492	0.9242
Brugia malayi	Protein kinase domain containing protein	0.0319	0.3825	0.3932
Trichomonas vaginalis	tubulin epsilon chain, putative	0.0293	0.3492	0.6574
Brugia malayi	Matrix metalloprotease, N-terminal domain containing protein	0.0026	0.0058	0.006
Loa Loa (eye worm)	hypothetical protein	0.0168	0.1887	0.194
Brugia malayi	G protein-coupled receptor	0.0168	0.1887	0.194
Onchocerca volvulus		0.0432	0.5276	0.5425
Plasmodium falciparum	cysteine proteinase falcipain 3	0.0027	0.0068	0.0038
Echinococcus granulosus	tubulin subunit beta	0.0293	0.3492	0.3492
Brugia malayi	hypothetical protein	0.0168	0.1887	0.194
Loa Loa (eye worm)	hypothetical protein	0.0168	0.1887	0.194
Plasmodium falciparum	cysteine proteinase falcipain 2a	0.0027	0.0068	0.0038
Echinococcus multilocularis	somatostatin receptor	0.0168	0.1887	0.1887
Schistosoma mansoni	tyrosine kinase	0.0206	0.2376	0.2376
Echinococcus granulosus	Mastin	0.0109	0.1129	0.1129
Schistosoma mansoni	adenoreceptor	0.0168	0.1887	0.1887
Echinococcus granulosus	Tubulin beta 2C chain	0.0293	0.3492	0.3492
Echinococcus granulosus	somatostatin receptor	0.0168	0.1887	0.1887
Onchocerca volvulus	Matrilysin homolog	0.0047	0.0332	0.0341
Onchocerca volvulus		0.0028	0.0088	0.009
Loa Loa (eye worm)	tubulin beta-4 chain	0.0293	0.3492	0.359
Trichomonas vaginalis	tubulin, putative	0.0293	0.3492	0.6574
Echinococcus multilocularis	cpg binding protein	0.003	0.0108	0.0108
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0168	0.1887	0.1887
Echinococcus granulosus	neuropeptide receptor	0.0168	0.1887	0.1887
Brugia malayi	Serotonin receptor	0.0168	0.1887	0.194
Echinococcus granulosus	geminin	0.0172	0.1942	0.1942
Giardia lamblia	Beta tubulin	0.0293	0.3492	0.6367
Onchocerca volvulus		0.0168	0.1887	0.194
Schistosoma mansoni	tubulin subunit beta	0.0293	0.3492	0.3492
Echinococcus multilocularis	neurogenic locus protein delta	0.005	0.0368	0.0368
Schistosoma mansoni	hypothetical protein	0.0168	0.1887	0.1887
Loa Loa (eye worm)	GTP-binding regulatory protein Gs alpha-S chain	0.0091	0.0897	0.0922
Echinococcus multilocularis	tyrosine protein kinase Abl	0.0102	0.1033	0.1033
Brugia malayi	notch-like transmembrane receptor	0.005	0.0368	0.0378
Schistosoma mansoni	cercarial elastase (S01 family)	0.0109	0.1129	0.1129
Brugia malayi	Dopamine receptor protein 1	0.0168	0.1887	0.194
Schistosoma mansoni	lamin	0.0027	0.0078	0.0078
Schistosoma mansoni	opsin-like receptor	0.0168	0.1887	0.1887
Loa Loa (eye worm)	PAN domain-containing protein	0.0092	0.0907	0.0933
Trypanosoma cruzi	cysteine peptidase C (CPC), putative	0.0142	0.1556	0.4039
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0091	0.0897	0.0897
Echinococcus granulosus	neuropeptides capa receptor	0.0168	0.1887	0.1887
Schistosoma mansoni	tyrosine kinase	0.0024	0.0039	0.0039
Toxoplasma gondii	microneme protein, putative	0.0092	0.0907	0.2294
Brugia malayi	sulfakinin receptor protein	0.0168	0.1887	0.194
Loa Loa (eye worm)	hypothetical protein	0.0168	0.1887	0.194
Loa Loa (eye worm)	hypothetical protein	0.0778	0.9726	1
Echinococcus multilocularis	Mastin	0.0109	0.1129	0.1129
Trichomonas vaginalis	tubulin epsilon chain, putative	0.0293	0.3492	0.6574
Echinococcus granulosus	tyrosine protein kinase Src42A	0.0039	0.0226	0.0226
Toxoplasma gondii	PAN domain-containing protein	0.0092	0.0907	0.2294
Brugia malayi	Low-density lipoprotein receptor repeat class B containing protein	0.0101	0.1029	0.1058
Echinococcus multilocularis	g protein coupled receptor	0.0168	0.1887	0.1887
Schistosoma mansoni	cpg binding protein	0.0028	0.0088	0.0088
Schistosoma mansoni	cercarial elastase (S01 family)	0.0109	0.1129	0.1129
Onchocerca volvulus		0.005	0.0368	0.0378
Schistosoma mansoni	cercarial elastase (S01 family)	0.0109	0.1129	0.1129
Echinococcus multilocularis	neurogenic locus notch protein	0.005	0.0368	0.0368
Schistosoma mansoni	peptide (allatostatin/somatostatin)-like receptor	0.0168	0.1887	0.1887
Echinococcus multilocularis	cathepsin L cysteine protease	0.0027	0.0068	0.0068
Toxoplasma gondii	PAN domain-containing protein	0.0092	0.0907	0.2294
Echinococcus multilocularis	CDC7 cell division cycle 7	0.0432	0.5276	0.5276
Schistosoma mansoni	notch	0.005	0.0368	0.0368
Echinococcus granulosus	rhodopsin orphan GPCR	0.0168	0.1887	0.1887
Toxoplasma gondii	microneme protein MIC17A	0.0092	0.0907	0.2294
Echinococcus granulosus	lamin	0.0027	0.0078	0.0078
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0043	0.0277	0.0277
Echinococcus granulosus	cathepsin l cysteine peptidase	0.0027	0.0068	0.0068
Schistosoma mansoni	hypothetical protein	0.0032	0.0137	0.0137
Echinococcus multilocularis	tyrosine protein kinase lyn tyrosine protein kinase blk	0.0053	0.0406	0.0406
Loa Loa (eye worm)	hypothetical protein	0.0315	0.3774	0.388
Schistosoma mansoni	biogenic amine (5HT) receptor	0.0168	0.1887	0.1887
Brugia malayi	Calcium binding EGF domain containing protein	0.005	0.0368	0.0378
Brugia malayi	EGF-like domain containing protein	0.005	0.0368	0.0378
Onchocerca volvulus		0.0432	0.5276	0.5425
Leishmania major	beta tubulin	0.0293	0.3492	0.9242
Echinococcus multilocularis	sex peptide receptor	0.0168	0.1887	0.1887
Echinococcus granulosus	Tubulin beta 2C chain	0.0293	0.3492	0.3492
Loa Loa (eye worm)	hypothetical protein	0.0101	0.1029	0.1058
Leishmania major	beta tubulin	0.0293	0.3492	0.9242
Loa Loa (eye worm)	hypothetical protein	0.0168	0.1887	0.194
Schistosoma mansoni	tubulin subunit beta	0.0293	0.3492	0.3492
Schistosoma mansoni	growth hormone secretagogue receptor	0.0168	0.1887	0.1887
Brugia malayi	PAN domain containing protein	0.0092	0.0907	0.0933
Mycobacterium tuberculosis	Conserved hypothetical protein	0.0155	0.172	0.5227
Brugia malayi	Papain family cysteine protease containing protein	0.0027	0.0068	0.007
Loa Loa (eye worm)	hypothetical protein	0.005	0.0368	0.0378
Schistosoma mansoni	neuropeptide f receptor 76f	0.0168	0.1887	0.1887
Schistosoma mansoni	cercarial elastase (S01 family)	0.0109	0.1129	0.1129
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0091	0.0897	0.0897
Brugia malayi	AKH receptor	0.0168	0.1887	0.194
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0168	0.1887	0.1887
Echinococcus multilocularis	notch	0.005	0.0368	0.0368
Onchocerca volvulus		0.0092	0.0907	0.0933
Brugia malayi	Tyrosine-protein kinase abl-1	0.0102	0.1033	0.1062
Schistosoma mansoni	subfamily S1A unassigned peptidase (S01 family)	0.0778	0.9726	0.9726
Echinococcus multilocularis	7TM GPCR, rhodopsin	0.0168	0.1887	0.1887
Leishmania major	cathepsin L-like protease	0.0027	0.0068	0.0038
Onchocerca volvulus		0.0778	0.9726	1
Brugia malayi	GCC2 and GCC3 family protein	0.005	0.0368	0.0378
Echinococcus granulosus	rhodopsin orphan GPCR	0.0168	0.1887	0.1887
Echinococcus granulosus	tyrosine protein kinase csk	0.0035	0.0175	0.0175
Onchocerca volvulus		0.005	0.0368	0.0378
Echinococcus granulosus	neurogenic locus notch protein	0.005	0.0368	0.0368
Echinococcus granulosus	transmembrane protease serine 3	0.0109	0.1129	0.1129
Echinococcus granulosus	lamin dm0	0.0027	0.0078	0.0078
Schistosoma mansoni	neuropeptide F-like receptor	0.0168	0.1887	0.1887
Schistosoma mansoni	biogenic amine receptor	0.0168	0.1887	0.1887
Loa Loa (eye worm)	TK/ABL protein kinase	0.0216	0.2509	0.258
Brugia malayi	Tubulin beta-1 chain	0.0293	0.3492	0.359
Loa Loa (eye worm)	trypsin family protein	0.0109	0.1129	0.1161
Brugia malayi	Cadherin domain containing protein	0.005	0.0368	0.0378
Onchocerca volvulus		0.0092	0.0907	0.0933
Echinococcus granulosus	diuretic hormone 44 receptor GPRdih2	0.0032	0.0137	0.0137
Brugia malayi	Trypsin family protein	0.0109	0.1129	0.1161
Trypanosoma cruzi	hypothetical protein, conserved	0.0315	0.3774	1
Brugia malayi	Transmembrane cell adhesion receptor mua-3 precursor, putative	0.005	0.0368	0.0378
Brugia malayi	Chymotrypsin-like protease CTRL-1 precursor	0.0109	0.1129	0.1161
Loa Loa (eye worm)	hypothetical protein	0.005	0.0368	0.0378
Brugia malayi	hypothetical protein	0.0037	0.02	0.0206
Echinococcus multilocularis	fibrillin 1	0.0101	0.1029	0.1029
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0027	0.0068	0.0041
Loa Loa (eye worm)	hypothetical protein	0.005	0.0368	0.0378
Brugia malayi	hypothetical protein	0.0168	0.1887	0.194
Echinococcus multilocularis	Tubulin beta 2C chain	0.0293	0.3492	0.3492
Onchocerca volvulus	Cathepsin F homolog	0.0027	0.0068	0.007
Loa Loa (eye worm)	intermediate filament tail domain-containing protein	0.0027	0.0078	0.008
Onchocerca volvulus		0.0027	0.0068	0.007
Schistosoma mansoni	hypothetical protein	0.005	0.0368	0.0368
Echinococcus granulosus	tissue type plasminogen activator	0.0315	0.3774	0.3774
Loa Loa (eye worm)	hypothetical protein	0.0168	0.1887	0.194
Onchocerca volvulus		0.0168	0.1887	0.194
Schistosoma mansoni	biogenic amine receptor	0.0168	0.1887	0.1887
Loa Loa (eye worm)	neuropeptide F receptor	0.0168	0.1887	0.194
Leishmania major	beta tubulin	0.0293	0.3492	0.9242
Brugia malayi	Calcitonin receptor-like protein seb-1	0.0101	0.1028	0.1057
Schistosoma mansoni	hypothetical protein	0.0109	0.1129	0.1129
Trypanosoma cruzi	cysteine peptidase, putative	0.0027	0.0068	0.0038
Echinococcus multilocularis	tyrosine protein kinase Btk29A	0.0024	0.0039	0.0039
Loa Loa (eye worm)	G-protein coupled receptor	0.0168	0.1887	0.194
Echinococcus multilocularis	protein jagged 2	0.005	0.0368	0.0368
Echinococcus granulosus	neuropeptides capa receptor	0.0168	0.1887	0.1887
Entamoeba histolytica	protein kinase, putative	0.0033	0.0144	0.0222
Brugia malayi	Dopamine receptor protein 1, putative (partial)	0.0168	0.1887	0.194
Onchocerca volvulus		0.0092	0.0907	0.0933
Loa Loa (eye worm)	hypothetical protein	0.0168	0.1887	0.194
Brugia malayi	Protein kinase domain containing protein	0.0432	0.5276	0.5425
Loa Loa (eye worm)	SH2 domain-containing protein	0.0041	0.0258	0.0265
Schistosoma mansoni	hypothetical protein	0.0069	0.0616	0.0616
Echinococcus multilocularis	serotonin receptor	0.0168	0.1887	0.1887
Toxoplasma gondii	hypothetical protein	0.0092	0.0907	0.2294
Onchocerca volvulus		0.0092	0.0907	0.0933
Loa Loa (eye worm)	Papain cysteine protease/cathepsin propeptide inhibitor-containing protein	0.0027	0.0068	0.007
Brugia malayi	Cathepsin L-like precursor	0.0027	0.0068	0.007
Schistosoma mansoni	hypothetical protein	0.0032	0.0137	0.0137
Brugia malayi	EGF-like domain containing protein	0.005	0.0368	0.0378
Loa Loa (eye worm)	hypothetical protein	0.0092	0.0907	0.0933
Onchocerca volvulus		0.0109	0.1129	0.1161
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0091	0.0897	0.0897
Echinococcus granulosus	G protein coupled receptor 139	0.0168	0.1887	0.1887
Schistosoma mansoni	hypothetical protein	0.005	0.0368	0.0368
Loa Loa (eye worm)	hypothetical protein	0.005	0.0368	0.0378
Loa Loa (eye worm)	neuropeptide F receptor	0.0168	0.1887	0.194
Loa Loa (eye worm)	hypothetical protein	0.0168	0.1887	0.194
Onchocerca volvulus	Slit protein homolog	0.005	0.0368	0.0378
Plasmodium falciparum	cysteine repeat modular protein 1	0.0315	0.3774	1
Echinococcus multilocularis	tyrosine protein kinase csk	0.0035	0.0175	0.0175
Schistosoma mansoni	tubulin subunit beta	0.0293	0.3492	0.3492
Brugia malayi	Protein kinase domain containing protein	0.0025	0.0045	0.0046
Trichomonas vaginalis	Clan CA, family C1, cathepsin B-like cysteine peptidase	0.005	0.0365	0.0571
Echinococcus granulosus	neuropeptide receptor A26	0.0168	0.1887	0.1887
Trypanosoma cruzi	cysteine peptidase, putative	0.0027	0.0068	0.0038
Brugia malayi	RE15519p	0.0168	0.1887	0.194
Brugia malayi	PAN domain containing protein	0.0092	0.0907	0.0933
Loa Loa (eye worm)	TK protein kinase	0.0033	0.0144	0.0148
Leishmania major	beta tubulin	0.0293	0.3492	0.9242
Echinococcus granulosus	Basic leucine zipper bZIP transcription	0.0037	0.02	0.02
Schistosoma mansoni	septate junction protein	0.005	0.0368	0.0368
Mycobacterium ulcerans	short chain dehydrogenase	0.0273	0.3237	1
Echinococcus multilocularis	tubulin subunit beta	0.0293	0.3492	0.3492
Echinococcus granulosus	tyrosine protein kinase Blk	0.0043	0.0277	0.0277
Loa Loa (eye worm)	BEN-1 protein	0.0293	0.3492	0.359
Onchocerca volvulus		0.0168	0.1887	0.194
Schistosoma mansoni	neuropeptide receptor	0.0168	0.1887	0.1887
Schistosoma mansoni	cathepsin F (C01 family)	0.0027	0.0068	0.0068
Loa Loa (eye worm)	hypothetical protein	0.0026	0.0058	0.006
Schistosoma mansoni	tubulin subunit beta	0.0293	0.3492	0.3492
Echinococcus granulosus	tyrosine protein kinase csk	0.0035	0.0175	0.0175
Onchocerca volvulus		0.0168	0.1887	0.194
Onchocerca volvulus		0.0092	0.0907	0.0933
Brugia malayi	SH2 domain containing protein	0.0045	0.0308	0.0317
Onchocerca volvulus		0.0045	0.0308	0.0317
Schistosoma mansoni	laminin gamma-3 chain	0.005	0.0368	0.0368
Echinococcus multilocularis	tyrosine protein kinase Src42A	0.0039	0.0226	0.0226
Onchocerca volvulus		0.0168	0.1887	0.194
Brugia malayi	GTP-binding regulatory protein Gs alpha-S chain, putative	0.0091	0.0897	0.0922
Brugia malayi	Trypsin family protein	0.0109	0.1129	0.1161
Onchocerca volvulus		0.0168	0.1887	0.194
Echinococcus granulosus	rhodopsin orphan GPCR	0.0168	0.1887	0.1887
Toxoplasma gondii	hypothetical protein	0.0047	0.0336	0.0759
Echinococcus granulosus	tyrosine kinase\|tyrosine protein kinase Fyn	0.0043	0.0277	0.0277
Leishmania major	cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like	0.005	0.0365	0.0838
Loa Loa (eye worm)	hypothetical protein	0.0168	0.1887	0.194
Loa Loa (eye worm)	hypothetical protein	0.0092	0.0907	0.0933
Brugia malayi	intermediate filament protein	0.0027	0.0078	0.008
Schistosoma mansoni	tubulin subunit beta	0.0293	0.3492	0.3492
Echinococcus granulosus	matrix metallopeptidase 7 M10 family	0.0077	0.0719	0.0719
Echinococcus multilocularis	neural cadherin	0.005	0.0368	0.0368
Echinococcus multilocularis	fibropellin Ia	0.005	0.0368	0.0368
Entamoeba histolytica	hypothetical protein	0.0037	0.02	0.0387
Onchocerca volvulus	Neuropeptide F receptor homolog	0.0168	0.1887	0.194
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0168	0.1887	0.1887
Echinococcus granulosus	tyrosine protein kinase Src42A	0.0053	0.0406	0.0406
Brugia malayi	G-protein-linked acetylcholine receptor protein 2, putative	0.0168	0.1887	0.194
Brugia malayi	Calcium binding EGF domain containing protein	0.005	0.0368	0.0378
Brugia malayi	Serotonin receptor	0.0168	0.1887	0.194
Loa Loa (eye worm)	hypothetical protein	0.0778	0.9726	1
Brugia malayi	hypothetical protein	0.0109	0.1129	0.1161
Toxoplasma gondii	cathepsin CPL	0.0027	0.0068	0.0038
Echinococcus multilocularis	allatostatin A receptor	0.0168	0.1887	0.1887
Leishmania major	beta tubulin	0.0293	0.3492	0.9242
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0053	0.0406	0.0406
Echinococcus granulosus	tyrosine protein kinase Lyn	0.0056	0.0451	0.0451
Entamoeba histolytica	tubulin family protein	0.0293	0.3492	1
Brugia malayi	hypothetical protein	0.0168	0.1887	0.194
Echinococcus granulosus	Peptidase S1 S6 chymotrypsin Hap	0.0109	0.1129	0.1129
Echinococcus granulosus	tachykinin peptides receptor 99D	0.0454	0.5562	0.5562
Echinococcus multilocularis	musashi	0.0027	0.0078	0.0078
Schistosoma mansoni	cpg binding protein	0.003	0.0108	0.0108
Onchocerca volvulus		0.0092	0.0907	0.0933
Echinococcus granulosus	alpha 1A adrenergic receptor	0.0168	0.1887	0.1887
Loa Loa (eye worm)	hypothetical protein	0.0027	0.0072	0.0074
Toxoplasma gondii	PAN/Apple domain-containing protein	0.0092	0.0907	0.2294
Brugia malayi	EGF-like domain containing protein	0.005	0.0368	0.0378
Echinococcus multilocularis	Tolloid protein 1	0.0101	0.1029	0.1029
Schistosoma mansoni	aminopeptidase PILS (M01 family)	0.0109	0.1129	0.1129
Onchocerca volvulus	Arrow homolog	0.0101	0.1029	0.1058
Brugia malayi	hypothetical protein	0.0168	0.1887	0.194
Loa Loa (eye worm)	cysteine protease	0.0027	0.0068	0.007
Loa Loa (eye worm)	hypothetical protein	0.0101	0.1028	0.1057
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0142	0.1556	0.1556
Loa Loa (eye worm)	bone morphogenetic protein 1b	0.0101	0.1029	0.1058
Entamoeba histolytica	hypothetical protein	0.0037	0.02	0.0387
Leishmania major	beta tubulin	0.0293	0.3492	0.9242
Loa Loa (eye worm)	TYRA-2 protein	0.0168	0.1887	0.194
Brugia malayi	putative neuropeptide receptor	0.0168	0.1887	0.194
Plasmodium vivax	vivapain-2	0.0027	0.0068	0.0038
Loa Loa (eye worm)	hypothetical protein	0.0168	0.1887	0.194
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0168	0.1887	0.1887
Trypanosoma brucei	beta tubulin	0.0293	0.3492	0.9944
Echinococcus granulosus	delta-like protein 1	0.005	0.0368	0.0368
Mycobacterium ulcerans	hypothetical protein	0.0109	0.1129	0.337
Echinococcus multilocularis	matrix metallopeptidase 7 (M10 family)	0.0077	0.0719	0.0719
Echinococcus granulosus	subfamily S1A unassigned peptidase S01 family	0.0109	0.1129	0.1129
Leishmania major	beta tubulin	0.0293	0.3492	0.9242
Echinococcus granulosus	proto oncogene tyrosine protein kinase LCK	0.0053	0.0406	0.0406
Brugia malayi	PAN domain containing protein	0.0092	0.0907	0.0933
Leishmania major	cathepsin L-like protease	0.0027	0.0068	0.0038
Schistosoma mansoni	tyrosine kinase	0.0053	0.0406	0.0406
Brugia malayi	PAN domain containing protein	0.0092	0.0907	0.0933
Toxoplasma gondii	calcium binding egf domain-containing protein	0.0101	0.1029	0.2621
Loa Loa (eye worm)	hypothetical protein	0.0168	0.1887	0.194
Brugia malayi	Trypsin family protein	0.0778	0.9726	1
Echinococcus multilocularis	tissue type plasminogen activator	0.0315	0.3774	0.3774
Loa Loa (eye worm)	hypothetical protein	0.005	0.0368	0.0378
Loa Loa (eye worm)	gonadotropin-releasing hormone receptor 2	0.0168	0.1887	0.194
Onchocerca volvulus		0.0027	0.0068	0.007
Loa Loa (eye worm)	hypothetical protein	0.0026	0.0054	0.0055
Loa Loa (eye worm)	tubulin beta-2A chain	0.0293	0.3492	0.359
Leishmania major	mitochondrial DNA polymerase beta	0.0294	0.3512	0.9295
Echinococcus multilocularis	orexin receptor type 2	0.0168	0.1887	0.1887
Plasmodium falciparum	tubulin beta chain	0.0293	0.3492	0.9242
Echinococcus multilocularis	neuropeptide FF receptor 2	0.0168	0.1887	0.1887
Loa Loa (eye worm)	hypothetical protein	0.0168	0.1887	0.194
Loa Loa (eye worm)	hypothetical protein	0.0168	0.1887	0.194
Leishmania major	beta tubulin	0.0293	0.3492	0.9242
Loa Loa (eye worm)	hypothetical protein	0.0168	0.1887	0.194
Echinococcus multilocularis	cysteine protease	0.0027	0.0068	0.0068
Loa Loa (eye worm)	hypothetical protein	0.005	0.0368	0.0378
Schistosoma mansoni	amine GPCR	0.0168	0.1887	0.1887
Echinococcus granulosus	7TM GPCR rhodopsin	0.0168	0.1887	0.1887
Onchocerca volvulus		0.005	0.0368	0.0378
Loa Loa (eye worm)	hypothetical protein	0.0092	0.0907	0.0933
Brugia malayi	putative neuropeptide receptor NPR1	0.0168	0.1887	0.194
Toxoplasma gondii	PAN domain-containing protein	0.0092	0.0907	0.2294
Schistosoma mansoni	Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)]	0.005	0.0368	0.0368
Loa Loa (eye worm)	PAN domain-containing protein	0.0092	0.0907	0.0933
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0168	0.1887	0.1887
Loa Loa (eye worm)	hypothetical protein	0.0168	0.1887	0.194
Loa Loa (eye worm)	hypothetical protein	0.0168	0.1887	0.194
Schistosoma mansoni	proto-oncogene tyrosine-protein kinase src	0.0024	0.0039	0.0039
Schistosoma mansoni	notch	0.005	0.0368	0.0368
Schistosoma mansoni	subfamily S1A unassigned peptidase (S01 family)	0.0109	0.1129	0.1129
Echinococcus granulosus	c src tyrosine kinase	0.0055	0.0438	0.0438
Echinococcus multilocularis	Tubulin beta 2C chain	0.0293	0.3492	0.3492
Loa Loa (eye worm)	hypothetical protein	0.005	0.0368	0.0378
Brugia malayi	Tachykinin-like peptides receptor 99D	0.0168	0.1887	0.194
Echinococcus multilocularis	diuretic hormone 44 receptor GPRdih2	0.0032	0.0137	0.0137
Loa Loa (eye worm)	BEN-1 protein	0.0293	0.3492	0.359
Loa Loa (eye worm)	ctsf protein	0.0027	0.0068	0.007
Echinococcus granulosus	tyrosine protein kinase Fyn	0.0053	0.0406	0.0406
Echinococcus multilocularis	neurogenic locus protein delta	0.005	0.0368	0.0368
Echinococcus multilocularis	g protein coupled receptor	0.0168	0.1887	0.1887
Loa Loa (eye worm)	hypothetical protein	0.0109	0.1129	0.1161
Giardia lamblia	High cysteine protein	0.005	0.0368	0.0005
Schistosoma mansoni	hypothetical protein	0.003	0.0113	0.0113
Echinococcus granulosus	dro:myosuppressin receptor	0.0168	0.1887	0.1887
Loa Loa (eye worm)	hypothetical protein	0.0069	0.0616	0.0633
Echinococcus granulosus	g protein coupled receptor	0.0168	0.1887	0.1887
Echinococcus multilocularis	geminin	0.0172	0.1942	0.1942
Brugia malayi	Tyrosine-protein kinase abl-1	0.0125	0.1331	0.1369
Schistosoma mansoni	hypothetical protein	0.005	0.0368	0.0368
Loa Loa (eye worm)	hypothetical protein	0.0168	0.1887	0.194
Echinococcus granulosus	g protein linked acetylcholine receptor gar 2a	0.0168	0.1887	0.1887
Echinococcus multilocularis	Tubulin beta 2C chain	0.0293	0.3492	0.3492
Echinococcus granulosus	tm gpcr rhodopsin	0.0168	0.1887	0.1887
Trypanosoma cruzi	cysteine peptidase C (CPC), putative	0.005	0.0365	0.0838
Echinococcus multilocularis	G protein coupled receptor 139	0.0168	0.1887	0.1887
Echinococcus granulosus	rhodopsin orphan GPCR	0.0168	0.1887	0.1887
Echinococcus multilocularis	tyrosine protein kinase HCK	0.0033	0.0144	0.0144
Brugia malayi	EGF-like domain containing protein	0.005	0.0368	0.0378
Loa Loa (eye worm)	PAN domain-containing protein	0.0092	0.0907	0.0933
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0168	0.1887	0.1887
Onchocerca volvulus		0.0168	0.1887	0.194
Echinococcus multilocularis	neuropeptide Y receptor	0.0168	0.1887	0.1887
Toxoplasma gondii	PAN domain-containing protein	0.0092	0.0907	0.2294
Trypanosoma brucei	beta tubulin	0.0293	0.3492	0.9944
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0027	0.0068	0.0041
Loa Loa (eye worm)	hypothetical protein	0.005	0.0368	0.0378
Leishmania major	mitochondrial DNA polymerase beta-PAK, putative	0.0139	0.1517	0.3934
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0142	0.1556	0.1556
Echinococcus granulosus	tyrosine kinase	0.0043	0.0277	0.0277
Loa Loa (eye worm)	hypothetical protein	0.005	0.0368	0.0378
Brugia malayi	Intermediate filament tail domain containing protein	0.0027	0.0078	0.008
Plasmodium falciparum	cysteine proteinase falcipain 2b	0.0027	0.0068	0.0038
Echinococcus multilocularis	c src tyrosine kinase	0.0055	0.0438	0.0438
Leishmania major	beta tubulin	0.0293	0.3492	0.9242
Onchocerca volvulus		0.0168	0.1887	0.194
Echinococcus multilocularis	transmembrane protease serine 3	0.0109	0.1129	0.1129
Onchocerca volvulus		0.0168	0.1887	0.194
Brugia malayi	PAN domain containing protein	0.0092	0.0907	0.0933
Schistosoma mansoni	hypothetical protein	0.0109	0.1129	0.1129
Schistosoma mansoni	biogenic amine (5HT) receptor	0.0168	0.1887	0.1887
Schistosoma mansoni	neuropeptide receptor	0.0168	0.1887	0.1887
Mycobacterium leprae	PROBABLE HYDROLASE	0.0026	0.0058	0.5
Echinococcus granulosus	laminin	0.0101	0.1029	0.1029
Schistosoma mansoni	serine/threonine protein kinase	0.0432	0.5276	0.5276
Onchocerca volvulus		0.0092	0.0907	0.0933
Schistosoma mansoni	peptide (FMRFamide/somatostatin)-like receptor	0.0168	0.1887	0.1887
Loa Loa (eye worm)	hypothetical protein	0.005	0.0368	0.0378
Trypanosoma cruzi	mitochondrial DNA polymerase beta-PAK, putative	0.005	0.0374	0.0862
Echinococcus granulosus	G protein coupled 5 hydroxytryptamine receptor	0.0168	0.1887	0.1887
Onchocerca volvulus		0.0168	0.1887	0.194
Loa Loa (eye worm)	pigment dispersing factor receptor c	0.0101	0.1028	0.1057
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0168	0.1887	0.1887
Loa Loa (eye worm)	PAN domain-containing protein	0.0092	0.0907	0.0933
Onchocerca volvulus		0.0092	0.0907	0.0933
Echinococcus multilocularis	neurogenic locus notch protein 4	0.005	0.0368	0.0368
Schistosoma mansoni	subfamily S1A unassigned peptidase (S01 family)	0.0109	0.1129	0.1129
Onchocerca volvulus		0.0027	0.0078	0.008
Onchocerca volvulus	Cathepsin L homolog	0.0027	0.0068	0.007
Schistosoma mansoni	hypothetical protein	0.0032	0.0137	0.0137
Schistosoma mansoni	muscarinic acetylcholine (GAR) receptor	0.0168	0.1887	0.1887
Leishmania major	cathepsin L-like protease	0.0027	0.0068	0.0038
Schistosoma mansoni	tyrosine kinase	0.0055	0.0438	0.0438
Toxoplasma gondii	microneme protein MIC4	0.0092	0.0907	0.2294
Echinococcus granulosus	peptide allatostatin:somatostatin	0.0168	0.1887	0.1887
Echinococcus multilocularis	subfamily S1A unassigned peptidase (S01 family)	0.0109	0.1129	0.1129
Schistosoma mansoni	egf-like domain protein	0.0101	0.1029	0.1029
Leishmania major	cysteine peptidase A (CPA)	0.0027	0.0068	0.0038
Echinococcus granulosus	CDC7 cell division cycle 7	0.0432	0.5276	0.5276
Brugia malayi	neuropeptide F receptor	0.0168	0.1887	0.194
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0168	0.1887	0.1887
Loa Loa (eye worm)	CXXC zinc finger family protein	0.0028	0.0088	0.009
Leishmania major	beta tubulin	0.0293	0.3492	0.9242
Onchocerca volvulus	Matrix metalloproteinase homolog	0.0047	0.0332	0.0341
Echinococcus granulosus	neurogenic locus notch protein	0.005	0.0368	0.0368
Echinococcus multilocularis	g protein linked acetylcholine receptor gar 2a	0.0168	0.1887	0.1887
Schistosoma mansoni	peptide (FMRFamide/neurokinin-3)-like receptor	0.0168	0.1887	0.1887
Echinococcus multilocularis	fmrfamide receptor	0.0168	0.1887	0.1887
Echinococcus multilocularis	neuropeptide s receptor	0.0168	0.1887	0.1887
Echinococcus multilocularis	thyrotropin releasing hormone receptor	0.0168	0.1887	0.1887
Echinococcus granulosus	g protein coupled receptor	0.0168	0.1887	0.1887
Brugia malayi	Corticotropin releasing factor receptor 2 precursor, putative	0.0101	0.1028	0.1057
Echinococcus granulosus	Tubulin beta 2C chain	0.0293	0.3492	0.3492
Loa Loa (eye worm)	hypothetical protein	0.0168	0.1887	0.194
Echinococcus multilocularis	tyrosine protein kinase Srms	0.0043	0.0277	0.0277
Schistosoma mansoni	notch	0.005	0.0368	0.0368
Schistosoma mansoni	histamine-responsive GPCR (AAF21638)	0.0168	0.1887	0.1887
Loa Loa (eye worm)	hypothetical protein	0.0027	0.0078	0.008
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0027	0.0068	0.0041
Onchocerca volvulus		0.0092	0.0907	0.0933
Onchocerca volvulus		0.0109	0.1129	0.1161
Brugia malayi	PAN domain containing protein	0.0092	0.0907	0.0933
Schistosoma mansoni	notch	0.005	0.0368	0.0368
Schistosoma mansoni	cercarial elastase (S01 family)	0.0109	0.1129	0.1129
Echinococcus multilocularis	G-protein coupled receptor, putative	0.0168	0.1887	0.1887
Brugia malayi	Melatonin receptor type 1A	0.0168	0.1887	0.194
Schistosoma mansoni	cercarial elastase (S01 family)	0.0109	0.1129	0.1129
Echinococcus multilocularis	laminin	0.0101	0.1029	0.1029
Echinococcus granulosus	g protein coupled receptor	0.0168	0.1887	0.1887
Echinococcus granulosus	glycoprotein Antigen 5	0.0109	0.1129	0.1129
Echinococcus multilocularis	neuropeptide Y receptor	0.0168	0.1887	0.1887
Echinococcus granulosus	g protein linked acetylcholine receptor gar 2a	0.0168	0.1887	0.1887
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0027	0.0068	0.0041
Echinococcus granulosus	sex peptide receptor	0.0168	0.1887	0.1887
Brugia malayi	ORL1-like opioid receptor	0.0168	0.1887	0.194
Schistosoma mansoni	cercarial elastase (S01 family)	0.0109	0.1129	0.1129
Loa Loa (eye worm)	hypothetical protein	0.0168	0.1887	0.194
Echinococcus granulosus	tyrosine protein kinase ABL1	0.0216	0.2509	0.2509
Echinococcus multilocularis	neuropeptides capa receptor	0.0168	0.1887	0.1887
Leishmania major	beta tubulin	0.0293	0.3492	0.9242
Schistosoma mansoni	hypothetical protein	0.005	0.0368	0.0368
Trypanosoma cruzi	mitochondrial DNA polymerase beta, putative	0.0294	0.3512	0.9295
Echinococcus granulosus	allatostatin A receptor	0.0168	0.1887	0.1887
Echinococcus granulosus	cathepsin l1	0.0027	0.0068	0.0068
Loa Loa (eye worm)	hypothetical protein	0.0109	0.1129	0.1161
Echinococcus granulosus	neuropeptide Y receptor	0.0168	0.1887	0.1887
Echinococcus multilocularis	beta tubulin	0.0293	0.3492	0.3492
Schistosoma mansoni	hypothetical protein	0.0315	0.3774	0.3774
Brugia malayi	PAN domain containing protein	0.0092	0.0907	0.0933
Loa Loa (eye worm)	5-hydroxytryptamine 2C receptor	0.0168	0.1887	0.194
Schistosoma mansoni	hypothetical protein	0.005	0.0368	0.0368
Echinococcus granulosus	intermediate filament protein	0.0027	0.0078	0.0078
Echinococcus multilocularis	tyrosine protein kinase Blk	0.0043	0.0277	0.0277
Onchocerca volvulus	Neurogenic locus notch homolog	0.005	0.0368	0.0378
Toxoplasma gondii	beta-1 tubulin, putative	0.0293	0.3492	0.9242
Loa Loa (eye worm)	beta-tubulin	0.0293	0.3492	0.359
Schistosoma mansoni	biogenic amine receptor	0.0168	0.1887	0.1887
Brugia malayi	Calcium binding EGF domain containing protein	0.0101	0.1029	0.1058
Loa Loa (eye worm)	SRC-1	0.0053	0.0406	0.0418
Echinococcus multilocularis	pyroglutamylated rfamide peptide receptor	0.0168	0.1887	0.1887
Echinococcus multilocularis	g protein coupled receptor	0.0168	0.1887	0.1887
Loa Loa (eye worm)	hypothetical protein	0.0168	0.1887	0.194
Loa Loa (eye worm)	hypothetical protein	0.0168	0.1887	0.194
Brugia malayi	hypothetical protein	0.0026	0.0054	0.0055
Trichomonas vaginalis	tubulin gamma chain, putative	0.0293	0.3492	0.6574
Loa Loa (eye worm)	G-protein coupled receptor	0.0168	0.1887	0.194
Brugia malayi	PAN domain containing protein	0.0092	0.0907	0.0933
Schistosoma mansoni	cercarial elastase (S01 family)	0.0109	0.1129	0.1129
Schistosoma mansoni	SmCB2 peptidase (C01 family)	0.0142	0.1556	0.1556
Echinococcus multilocularis	tyrosine protein kinase csk	0.0035	0.0175	0.0175
Leishmania major	beta tubulin	0.0293	0.3492	0.9242
Brugia malayi	EGF-like domain containing protein	0.005	0.0368	0.0378
Echinococcus granulosus	enteropeptidase	0.0109	0.1129	0.1129
Loa Loa (eye worm)	TK/CSK protein kinase	0.0035	0.0175	0.018
Brugia malayi	hypothetical protein	0.0168	0.1887	0.194
Loa Loa (eye worm)	hypothetical protein	0.005	0.0368	0.0378
Loa Loa (eye worm)	hypothetical protein	0.005	0.0368	0.0378
Echinococcus multilocularis	cathepsin b	0.0142	0.1556	0.1556
Echinococcus granulosus	cathepsin b	0.0142	0.1556	0.1556
Schistosoma mansoni	hypothetical protein	0.0168	0.1887	0.1887
Onchocerca volvulus		0.003	0.0113	0.0116
Brugia malayi	EGF-like domain containing protein	0.005	0.0368	0.0378
Onchocerca volvulus		0.0027	0.0068	0.007
Loa Loa (eye worm)	hypothetical protein	0.0142	0.1556	0.16
Plasmodium vivax	vivapain-2	0.0027	0.0068	0.0038
Leishmania major	hypothetical protein, conserved	0.0315	0.3774	1
Trypanosoma cruzi	DNA polymerase beta thumb, putative	0.0041	0.0258	0.0549
Schistosoma mansoni	cathepsin F (C01 family)	0.0027	0.0068	0.0068
Echinococcus multilocularis	cathepsin l cysteine peptidase	0.0027	0.0068	0.0068
Echinococcus granulosus	slit 2 protein	0.005	0.0368	0.0368
Schistosoma mansoni	neuropeptide receptor	0.0168	0.1887	0.1887
Echinococcus granulosus	3'partial\|tyrosine protein kinase Fgr	0.0053	0.0406	0.0406
Schistosoma mansoni	hypothetical protein	0.0168	0.1887	0.1887
Schistosoma mansoni	subfamily S1A unassigned peptidase (S01 family)	0.0109	0.1129	0.1129
Loa Loa (eye worm)	hypothetical protein	0.0168	0.1887	0.194
Brugia malayi	Muscle positioning protein 4	0.005	0.0368	0.0378
Echinococcus multilocularis	Peptidase S1 S6, chymotrypsin Hap	0.0109	0.1129	0.1129
Brugia malayi	gonadotropin-releasing hormone receptor 2	0.0168	0.1887	0.194
Brugia malayi	Hemopexin family protein	0.003	0.0113	0.0116
Schistosoma mansoni	subfamily S1A unassigned peptidase (S01 family)	0.0109	0.1129	0.1129
Trypanosoma cruzi	DNA polymerase beta thumb, putative	0.0041	0.0258	0.0549
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.005	0.0365	0.0365
Loa Loa (eye worm)	fibroinase	0.0027	0.0068	0.007
Echinococcus granulosus	rhodopsin orphan GPCR	0.0168	0.1887	0.1887
Echinococcus granulosus	rhodopsin orphan GPCR	0.0168	0.1887	0.1887
Echinococcus multilocularis	Tubulin beta 2C chain	0.0293	0.3492	0.3492
Echinococcus granulosus	tyrosine protein kinase Fyn	0.0053	0.0406	0.0406
Schistosoma mansoni	amine GPCR	0.0168	0.1887	0.1887
Onchocerca volvulus		0.0168	0.1887	0.194
Echinococcus multilocularis	tyrosine protein kinase ABL1	0.0216	0.2509	0.2509
Loa Loa (eye worm)	hypothetical protein	0.0168	0.1887	0.194
Brugia malayi	Trypsin family protein	0.0109	0.1129	0.1161
Schistosoma mansoni	notch	0.005	0.0368	0.0368
Schistosoma mansoni	ancient conserved domain protein 2 (cyclin m2)	0.0168	0.1887	0.1887
Onchocerca volvulus	Neurogenic locus notch protein homolog	0.005	0.0368	0.0378
Onchocerca volvulus		0.0168	0.1887	0.194
Echinococcus granulosus	7tm_1 domain containing protein	0.0168	0.1887	0.1887
Brugia malayi	Cathepsin L-like precursor	0.0027	0.0068	0.007
Echinococcus granulosus	cadherin EGF LAG seven pass G type receptor	0.0032	0.0137	0.0137
Schistosoma mansoni	amine GPCR	0.0168	0.1887	0.1887
Loa Loa (eye worm)	hypothetical protein	0.0101	0.1029	0.1058
Schistosoma mansoni	transcription factor LCR-F1	0.0037	0.02	0.02
Onchocerca volvulus		0.0109	0.1129	0.1161
Onchocerca volvulus		0.0315	0.3774	0.388
Toxoplasma gondii	cathepsin B	0.005	0.0365	0.0838
Echinococcus multilocularis	slit 2 protein	0.005	0.0368	0.0368
Brugia malayi	G-protein coupled receptor	0.0168	0.1887	0.194
Echinococcus multilocularis	dro:myosuppressin receptor	0.0168	0.1887	0.1887
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0168	0.1887	0.1887
Schistosoma mansoni	cercarial elastase (S01 family)	0.0109	0.1129	0.1129
Brugia malayi	Unidentified vitellogenin-linked transcript protein 6, putative	0.0168	0.1887	0.194
Echinococcus granulosus	protein jagged 1	0.005	0.0368	0.0368
Echinococcus granulosus	hypothetical protein	0.0168	0.1887	0.1887
Loa Loa (eye worm)	hypothetical protein	0.0168	0.1887	0.194
Toxoplasma gondii	calcium binding egf domain-containing protein	0.0101	0.1029	0.2621
Echinococcus granulosus	notch	0.005	0.0368	0.0368
Loa Loa (eye worm)	G-protein-linked acetylcholine receptor protein 2	0.0168	0.1887	0.194
Leishmania major	beta tubulin	0.0293	0.3492	0.9242
Echinococcus granulosus	fibropellin Ia	0.005	0.0368	0.0368
Toxoplasma gondii	hypothetical protein	0.0092	0.0907	0.2294
Echinococcus granulosus	protein jagged 1	0.005	0.0368	0.0368
Loa Loa (eye worm)	CDC7 protein kinase	0.0432	0.5276	0.5425
Schistosoma mansoni	hypothetical protein	0.005	0.0368	0.0368
Echinococcus multilocularis	g protein linked acetylcholine receptor gar 2a	0.0168	0.1887	0.1887
Schistosoma mansoni	biogenic amine (octopamine/dopamine) receptor	0.0168	0.1887	0.1887
Echinococcus multilocularis	tyrosine protein kinase Fgr	0.0053	0.0406	0.0406
Echinococcus granulosus	neurogenic locus protein delta	0.005	0.0368	0.0368
Schistosoma mansoni	hypothetical protein	0.0037	0.02	0.02
Trypanosoma cruzi	cruzipain precursor, putative	0.0027	0.0068	0.0038
Trypanosoma brucei	mitochondrial DNA polymerase beta	0.0294	0.3512	1
Trypanosoma cruzi	cysteine peptidase, putative	0.0027	0.0068	0.0038
Brugia malayi	hypothetical protein	0.0168	0.1887	0.194
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0142	0.1556	0.1556
Brugia malayi	hypothetical protein	0.0168	0.1887	0.194
Onchocerca volvulus	Putative cubilin	0.005	0.0368	0.0378
Brugia malayi	hypothetical protein	0.0168	0.1887	0.194
Loa Loa (eye worm)	hypothetical protein	0.0168	0.1887	0.194
Onchocerca volvulus	Dopamine\/Ecdysteroid receptor homolog	0.0168	0.1887	0.194
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0168	0.1887	0.1887
Brugia malayi	CXXC zinc finger family protein	0.0028	0.0088	0.009
Toxoplasma gondii	PAN domain-containing protein	0.0092	0.0907	0.2294
Echinococcus multilocularis	enteropeptidase	0.0109	0.1129	0.1129
Echinococcus multilocularis	Basic leucine zipper (bZIP) transcription	0.0037	0.02	0.02
Schistosoma mansoni	hypothetical protein	0.0168	0.1887	0.1887
Loa Loa (eye worm)	unidentified vitellogenin-linked transcript protein 6	0.0168	0.1887	0.194
Brugia malayi	Dopamine receptor protein 2	0.0168	0.1887	0.194
Loa Loa (eye worm)	hypothetical protein	0.0168	0.1887	0.194
Brugia malayi	Delta serrate ligand family protein	0.005	0.0368	0.0378
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0027	0.0068	0.0041
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0168	0.1887	0.1887
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0168	0.1887	0.1887
Echinococcus granulosus	biogenic amine 5HT receptor	0.0168	0.1887	0.1887
Echinococcus multilocularis	tachykinin peptides receptor 99D	0.0454	0.5562	0.5562
Echinococcus multilocularis	neurogenic locus notch protein	0.005	0.0368	0.0368
Echinococcus multilocularis	tyrosine protein kinase csk	0.0035	0.0175	0.0175
Leishmania major	cathepsin L-like protease	0.0027	0.0068	0.0038
Echinococcus multilocularis	glycoprotein Antigen 5	0.0109	0.1129	0.1129
Schistosoma mansoni	mixed-lineage leukemia protein mll	0.006	0.0493	0.0493
Loa Loa (eye worm)	hypothetical protein	0.0109	0.1129	0.1161
Loa Loa (eye worm)	latrophilin receptor protein 2	0.0032	0.0137	0.0141
Loa Loa (eye worm)	hypothetical protein	0.005	0.0368	0.0378
Echinococcus multilocularis	lamin dm0	0.0027	0.0078	0.0078
Schistosoma mansoni	histamine h1 receptor	0.0168	0.1887	0.1887
Loa Loa (eye worm)	hypothetical protein	0.0168	0.1887	0.194
Loa Loa (eye worm)	multiple epidermal growth factor-like domains 6	0.0101	0.1029	0.1058
Echinococcus multilocularis	tyrosine protein kinase Src64B	0.0053	0.0406	0.0406
Loa Loa (eye worm)	hypothetical protein	0.0109	0.1129	0.1161
Loa Loa (eye worm)	hypothetical protein	0.005	0.0368	0.0378
Echinococcus granulosus	Tolloid protein 1	0.0101	0.1029	0.1029
Giardia lamblia	Beta tubulin	0.0293	0.3492	0.6367
Loa Loa (eye worm)	hypothetical protein	0.0168	0.1887	0.194
Onchocerca volvulus	Cathepsin L homolog	0.0027	0.0068	0.007
Echinococcus granulosus	orexin receptor type 2	0.0168	0.1887	0.1887
Loa Loa (eye worm)	hypothetical protein	0.0081	0.077	0.0792
Echinococcus granulosus	growth hormone secretagogue receptor type 1	0.0168	0.1887	0.1887
Loa Loa (eye worm)	hypothetical protein	0.0101	0.1029	0.1058
Brugia malayi	beta-tubulin, identical	0.0293	0.3492	0.359
Schistosoma mansoni	alpha-1 adrenergic receptor	0.0168	0.1887	0.1887
Schistosoma mansoni	cercarial elastase (S01 family)	0.0109	0.1129	0.1129
Leishmania major	cathepsin L-like protease	0.0027	0.0068	0.0038
Brugia malayi	Cathepsin L-like precursor	0.0027	0.0068	0.007
Echinococcus granulosus	neuropeptide FF receptor 2	0.0168	0.1887	0.1887
Schistosoma mansoni	cell polarity protein	0.005	0.0368	0.0368
Echinococcus multilocularis	tyrosine protein kinase csk	0.0035	0.0175	0.0175
Loa Loa (eye worm)	hypothetical protein	0.0168	0.1887	0.194
Echinococcus multilocularis	neuropeptide receptor A26	0.0168	0.1887	0.1887
Loa Loa (eye worm)	hypothetical protein	0.005	0.0368	0.0378
Echinococcus granulosus	tubulin beta 1 chain	0.0293	0.3492	0.3492
Schistosoma mansoni	opsin-like receptor	0.0168	0.1887	0.1887
Loa Loa (eye worm)	cathepsin B	0.005	0.0365	0.0376
Loa Loa (eye worm)	hypothetical protein	0.0168	0.1887	0.194
Loa Loa (eye worm)	hypothetical protein	0.0092	0.0907	0.0933
Onchocerca volvulus		0.0168	0.1887	0.194
Loa Loa (eye worm)	papain family cysteine protease containing protein	0.0027	0.0068	0.007
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0168	0.1887	0.1887
Schistosoma mansoni	tubulin subunit beta	0.0293	0.3492	0.3492
Entamoeba histolytica	hypothetical protein	0.0037	0.02	0.0387
Toxoplasma gondii	EGF family domain-containing protein	0.005	0.0368	0.0845
Brugia malayi	Matrixin family protein	0.0051	0.0386	0.0397
Schistosoma mansoni	subfamily S1A unassigned peptidase (S01 family)	0.0109	0.1129	0.1129
Echinococcus granulosus	thyrotropin releasing hormone receptor	0.0168	0.1887	0.1887
Entamoeba histolytica	tubulin family protein	0.0293	0.3492	1
Schistosoma mansoni	subfamily M12A unassigned peptidase (M12 family)	0.0101	0.1029	0.1029
Loa Loa (eye worm)	hypothetical protein	0.0027	0.0068	0.007
Echinococcus granulosus	cathepsin L cysteine proteinase	0.0027	0.0068	0.0068
Brugia malayi	Kringle domain containing protein	0.0315	0.3774	0.388
Echinococcus granulosus	tyrosine protein kinase Btk29A	0.0024	0.0039	0.0039
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0168	0.1887	0.1887
Echinococcus multilocularis	serotonin receptor	0.0168	0.1887	0.1887
Echinococcus granulosus	tyrosine protein kinase csk	0.0035	0.0175	0.0175

Activities

Activity type	Activity value	Assay description	Source	Reference
RBA (binding)	= 59 %	Percent of relative binding affinity ( to that of estradiol) for estrogen receptor determined by competitive radiometric binding assay using [3H]-estradiol as tracer in rat uterine cytosol	ChEMBL.	2769689
RBA (binding)	= 59 %	Binding affinity for rat uterine estrogen receptor relative to estradiol	ChEMBL.	3385728
RBA (binding)	= 59 %	Percent of relative binding affinity ( to that of estradiol) for estrogen receptor determined by competitive radiometric binding assay using [3H]-estradiol as tracer in rat uterine cytosol	ChEMBL.	2769689
RBA (binding)	= 59 %	Binding affinity for rat uterine estrogen receptor relative to estradiol	ChEMBL.	3385728

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

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External resources for this compound

No external resources registered for this compound

Bibliographic References

2 literature references were collected for this gene.

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Detailed information for compound 33613