Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium ulcerans | hypothetical protein | 0.0039 | 0.037 | 0.2038 |
Loa Loa (eye worm) | hypothetical protein | 0.0241 | 0.2844 | 0.7181 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0027 | 0.0223 | 0.0446 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.001 | 0.0025 | 0.0025 |
Loa Loa (eye worm) | histone methyltransferase | 0.001 | 0.0021 | 0.0053 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0019 | 0.0133 | 0.0336 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0012 | 0.0031 |
Giardia lamblia | NADH oxidase lateral transfer candidate | 0.0014 | 0.0072 | 0.0152 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.001 | 0.0025 | 0.0049 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.0019 | 0.0133 | 0.0305 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0012 | 0.0031 |
Echinococcus granulosus | CAAX prenyl protease 2 | 0.0187 | 0.2182 | 0.4368 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0025 | 0.0062 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.0468 | 0.0938 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.001 | 0.0025 | 0.0062 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.0347 | 0.0847 |
Mycobacterium ulcerans | hypothetical protein | 0.0039 | 0.037 | 0.2038 |
Brugia malayi | CXXC zinc finger family protein | 0.0029 | 0.0256 | 0.0647 |
Echinococcus multilocularis | transcriptional factor nfil3:e4bp4 | 0.0009 | 0.0012 | 0.0012 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.001 | 0.0025 | 0.0049 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.001 | 0.0025 | 0.0025 |
Onchocerca volvulus | Huntingtin homolog | 0.0125 | 0.1425 | 0.3577 |
Echinococcus granulosus | glycogen phosphorylase | 0.0333 | 0.3961 | 0.7932 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.0292 | 0.0584 |
Leishmania major | hypothetical protein, conserved | 0.0026 | 0.0213 | 0.0665 |
Toxoplasma gondii | thioredoxin reductase | 0.0041 | 0.04 | 0.4875 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.001 | 0.0025 | 0.0025 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.0292 | 0.0584 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0032 | 0.0292 | 0.0292 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.001 | 0.0025 | 0.0062 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0037 | 0.0347 | 0.0695 |
Echinococcus granulosus | protocadherin 11 | 0.0009 | 0.0012 | 0.0025 |
Schistosoma mansoni | coup transcription factor | 0.001 | 0.0025 | 0.0049 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0019 | 0.0133 | 0.1851 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0094 | 0.1042 | 0.6201 |
Loa Loa (eye worm) | hypothetical protein | 0.0187 | 0.2182 | 0.5508 |
Trichomonas vaginalis | Clan MA, family M48, Ste24 endopeptidase-like metallopeptidase | 0.0069 | 0.0744 | 0.1794 |
Onchocerca volvulus | 0.0016 | 0.0099 | 0.022 | |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.001 | 0.0025 | 0.0049 |
Loa Loa (eye worm) | steroid hormone receptor | 0.001 | 0.0025 | 0.0062 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0122 | 0.1386 | 0.3499 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0019 | 0.0133 | 0.0235 |
Brugia malayi | alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase | 0.001 | 0.0026 | 0.0066 |
Brugia malayi | beta-NAC-like protein | 0.0036 | 0.0334 | 0.0844 |
Mycobacterium ulcerans | integral membrane protein | 0.0039 | 0.037 | 0.2038 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.001 | 0.0025 | 0.0062 |
Onchocerca volvulus | 0.0027 | 0.0223 | 0.0533 | |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.0333 | 0.3961 | 1 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0027 | 0.0223 | 0.0223 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0241 | 0.2844 | 0.2844 |
Trichomonas vaginalis | Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase | 0.0038 | 0.0359 | 0.0812 |
Trichomonas vaginalis | glutathione reductase, putative | 0.0014 | 0.0072 | 0.008 |
Echinococcus granulosus | GPCR family 2 | 0.0032 | 0.0292 | 0.0584 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0023 | 0.0178 | 0.035 |
Echinococcus multilocularis | glycogen phosphorylase | 0.0333 | 0.3961 | 0.3961 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein | 0.001 | 0.0026 | 0.0066 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0099 | 0.025 |
Schistosoma mansoni | hypothetical protein | 0.0418 | 0.4994 | 1 |
Trypanosoma brucei | ubiquitin carboxyl-terminal hydrolase, putative | 0.0038 | 0.0359 | 0.1361 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.001 | 0.0025 | 0.0025 |
Trichomonas vaginalis | glycogen phosphorylase, putative | 0.0333 | 0.3961 | 1 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0041 | 0.04 | 0.1009 |
Echinococcus multilocularis | protocadherin 11 | 0.0009 | 0.0012 | 0.0012 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0032 | 0.0292 | 0.0584 |
Trypanosoma brucei | trypanothione reductase | 0.0041 | 0.04 | 0.1553 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.001 | 0.0025 | 0.0031 |
Brugia malayi | hypothetical protein | 0.0241 | 0.2844 | 0.7181 |
Mycobacterium tuberculosis | Probable glycogen phosphorylase GlgP | 0.0144 | 0.1655 | 1 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0049 | 0.05 | 0.1261 |
Onchocerca volvulus | 0.0015 | 0.0085 | 0.0184 | |
Schistosoma mansoni | family U48 unassigned peptidase (U48 family) | 0.0187 | 0.2182 | 0.4368 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0032 | 0.0292 | 0.0736 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0104 | 0.1169 | 1 |
Echinococcus multilocularis | GPCR, family 2 | 0.0032 | 0.0292 | 0.0292 |
Mycobacterium ulcerans | glycogen phosphorylase GlgP | 0.0144 | 0.1655 | 1 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.001 | 0.0025 | 0.0049 |
Brugia malayi | Muscle positioning protein 4 | 0.0015 | 0.0085 | 0.0215 |
Schistosoma mansoni | survival motor neuron protein | 0.0049 | 0.05 | 0.1 |
Brugia malayi | nuclear hormone receptor | 0.001 | 0.0025 | 0.0062 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.001 | 0.0025 | 0.0062 |
Toxoplasma gondii | hypothetical protein | 0.0039 | 0.037 | 0.4427 |
Giardia lamblia | Ubiquitin carboxyl-terminal hydrolase 4 | 0.0038 | 0.0359 | 0.0879 |
Leishmania major | CAAX prenyl protease 1, putative,metallo-peptidase, Clan M-, Family M48 | 0.0069 | 0.0744 | 0.3185 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0099 | 0.025 |
Schistosoma mansoni | farnesylated-protein converting enzyme 1 (M48 family) | 0.0069 | 0.0744 | 0.149 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.001 | 0.0025 | 0.0062 |
Loa Loa (eye worm) | glutathione reductase | 0.0041 | 0.04 | 0.1009 |
Schistosoma mansoni | hypothetical protein | 0.0037 | 0.0347 | 0.0695 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.001 | 0.0025 | 0.0031 |
Brugia malayi | steroid hormone receptor | 0.001 | 0.0025 | 0.0062 |
Schistosoma mansoni | family U48 unassigned peptidase (U48 family) | 0.0187 | 0.2182 | 0.4368 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0085 | 0.0215 |
Trypanosoma cruzi | transcription factor btf3, putative | 0.0036 | 0.0334 | 0.1242 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0037 | 0.0347 | 0.0695 |
Brugia malayi | glutathione reductase | 0.0041 | 0.04 | 0.1009 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0037 | 0.0347 | 0.0347 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.001 | 0.0025 | 0.0062 |
Entamoeba histolytica | transcription factor BTF3, putative | 0.0036 | 0.0334 | 0.0815 |
Echinococcus granulosus | Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 | 0.0038 | 0.0359 | 0.072 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0014 | 0.0072 | 0.3419 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0085 | 0.0215 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.0292 | 0.0584 |
Echinococcus multilocularis | cpg binding protein | 0.0031 | 0.0277 | 0.0277 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0292 | 0.0736 |
Echinococcus granulosus | transcriptional factor nfil3:e4bp4 | 0.0009 | 0.0012 | 0.0025 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.001 | 0.0025 | 0.0062 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0036 | 0.0334 | 0.0748 |
Loa Loa (eye worm) | bZIP transcription factor family protein | 0.0009 | 0.0012 | 0.0031 |
Toxoplasma gondii | hypothetical protein | 0.0039 | 0.037 | 0.4427 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0023 | 0.0178 | 0.035 |
Brugia malayi | Peptidase family M48 containing protein | 0.0069 | 0.0744 | 0.1878 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0041 | 0.04 | 0.04 |
Echinococcus multilocularis | glycogen phosphorylase | 0.0333 | 0.3961 | 0.3961 |
Schistosoma mansoni | thyroid hormone receptor | 0.001 | 0.0025 | 0.0049 |
Trypanosoma cruzi | ubiquitin carboxyl-terminal hydrolase, putative | 0.0038 | 0.0359 | 0.1361 |
Loa Loa (eye worm) | hypothetical protein | 0.0125 | 0.1425 | 0.3597 |
Plasmodium falciparum | glutathione reductase | 0.0041 | 0.04 | 1 |
Leishmania major | CAAX prenyl protease 2, putative,peptidase with unknown catalytic mechanism (family U48) | 0.0187 | 0.2182 | 1 |
Mycobacterium tuberculosis | Probable conserved integral membrane protein | 0.0039 | 0.037 | 0.2038 |
Onchocerca volvulus | 0.0015 | 0.0085 | 0.0184 | |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0019 | 0.0133 | 0.0287 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0241 | 0.2844 | 0.5696 |
Chlamydia trachomatis | glycogen phosphorylase | 0.0333 | 0.3961 | 1 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription factor | 0.0009 | 0.0012 | 0.0025 |
Trypanosoma brucei | metallo- peptidase, Clan M- Family M48 | 0.0069 | 0.0744 | 0.3185 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0213 | 0.0537 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0099 | 0.0199 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.001 | 0.0025 | 0.0062 |
Schistosoma mansoni | ubiquitin-specific peptidase 8 (C19 family) | 0.0038 | 0.0359 | 0.072 |
Brugia malayi | Cell death specification protein 2 | 0.0009 | 0.0012 | 0.0031 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.001 | 0.0025 | 0.0062 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription factor | 0.0009 | 0.0012 | 0.0012 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.001 | 0.0021 | 0.0042 |
Echinococcus granulosus | X box binding protein 1 | 0.0294 | 0.3488 | 0.6984 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.001 | 0.0021 | 0.0021 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.001 | 0.0025 | 0.0062 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0038 | 0.0359 | 0.0812 |
Echinococcus multilocularis | protocadherin 11 | 0.0009 | 0.0012 | 0.0012 |
Brugia malayi | hypothetical protein | 0.0009 | 0.0012 | 0.0031 |
Trypanosoma cruzi | ubiquitin carboxyl-terminal hydrolase, putative | 0.0038 | 0.0359 | 0.1361 |
Brugia malayi | Hepatic leukemia factor | 0.0009 | 0.0012 | 0.0031 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0027 | 0.0223 | 0.0446 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0102 | 0.1141 | 0.288 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.001 | 0.0025 | 0.0062 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.001 | 0.0025 | 0.0049 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0025 | 0.0062 |
Trichomonas vaginalis | Clan MA, family M48, Ste24 endopeptidase-like metallopeptidase | 0.0069 | 0.0744 | 0.1794 |
Echinococcus multilocularis | CAAX prenyl protease 2 | 0.0187 | 0.2182 | 0.2182 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0099 | 0.0199 |
Onchocerca volvulus | 0.001 | 0.0025 | 0.0031 | |
Brugia malayi | Cell death specification protein 2 | 0.0009 | 0.0012 | 0.0031 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0025 | 0.0062 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.001 | 0.0025 | 0.0049 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0025 | 0.0062 |
Schistosoma mansoni | glycogen phosphorylase | 0.0333 | 0.3961 | 0.7932 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.0468 | 0.0938 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.001 | 0.0025 | 0.0049 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0025 | 0.0062 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.0347 | 0.0847 |
Brugia malayi | bZIP transcription factor family protein | 0.0009 | 0.0012 | 0.0031 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0181 | 0.2112 | 0.5333 |
Echinococcus granulosus | ubiquitin carboxyl terminal hydrolase 8 | 0.0038 | 0.0359 | 0.072 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.001 | 0.0025 | 0.0049 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0041 | 0.04 | 0.1553 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.001 | 0.0025 | 0.0025 |
Brugia malayi | hypothetical protein | 0.0009 | 0.0012 | 0.0031 |
Schistosoma mansoni | cpg binding protein | 0.0031 | 0.0277 | 0.0554 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0041 | 0.04 | 0.2224 |
Mycobacterium tuberculosis | Probable reductase | 0.0094 | 0.1042 | 0.6201 |
Schistosoma mansoni | cpg binding protein | 0.0031 | 0.0277 | 0.0554 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0014 | 0.0072 | 0.0183 |
Echinococcus multilocularis | ccaat enhancer binding protein delta ccaat enhancer binding protein beta | 0.0009 | 0.0012 | 0.0012 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.001 | 0.0025 | 0.0062 |
Schistosoma mansoni | glycogen phosphorylase | 0.0144 | 0.1655 | 0.3314 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase, LpdB | 0.0014 | 0.0072 | 0.0195 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.001 | 0.0025 | 0.0025 |
Echinococcus multilocularis | MAM | 0.0016 | 0.0099 | 0.0099 |
Echinococcus multilocularis | FTZ F1 alpha | 0.001 | 0.0025 | 0.0025 |
Onchocerca volvulus | 0.0015 | 0.0085 | 0.0184 | |
Loa Loa (eye worm) | TK/ALK protein kinase | 0.0016 | 0.0099 | 0.025 |
Echinococcus granulosus | cpg binding protein | 0.0031 | 0.0277 | 0.0554 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.001 | 0.0025 | 0.0049 |
Brugia malayi | hypothetical protein | 0.0017 | 0.0101 | 0.0256 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0029 | 0.0256 | 0.0647 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0094 | 0.1042 | 0.6201 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0019 | 0.0133 | 0.0287 |
Brugia malayi | nuclear receptor NHR-88 | 0.001 | 0.0025 | 0.0062 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.001 | 0.0025 | 0.0049 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.001 | 0.0025 | 0.0025 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase | 0.0014 | 0.0072 | 0.0195 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0036 | 0.0334 | 0.0748 |
Brugia malayi | CAAX amino terminal protease family protein | 0.0187 | 0.2182 | 0.5508 |
Loa Loa (eye worm) | DOMON domain-containing protein | 0.0015 | 0.0085 | 0.0215 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.001 | 0.0025 | 0.0062 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0026 | 0.0213 | 0.0665 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0025 | 0.0062 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0026 | 0.0213 | 0.0665 |
Chlamydia trachomatis | hypothetical protein | 0.0039 | 0.037 | 0.0765 |
Treponema pallidum | hypothetical protein | 0.0039 | 0.037 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.001 | 0.0025 | 0.0062 |
Schistosoma mansoni | hypothetical protein | 0.0009 | 0.0012 | 0.0025 |
Toxoplasma gondii | CAAX metallo endopeptidase | 0.0069 | 0.0744 | 1 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.0019 | 0.0133 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.001 | 0.0025 | 0.0062 |
Toxoplasma gondii | exonuclease III APE | 0.0019 | 0.0133 | 0.0902 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.0468 | 0.0938 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0094 | 0.1042 | 0.6201 |
Brugia malayi | Pre-SET motif family protein | 0.0181 | 0.2112 | 0.5333 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0047 | 0.0468 | 0.1183 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.007 | 0.0748 | 0.1888 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0047 | 0.0468 | 0.0938 |
Loa Loa (eye worm) | hypothetical protein | 0.0102 | 0.1141 | 0.288 |
Mycobacterium ulcerans | flavoprotein disulfide reductase | 0.0014 | 0.0072 | 0.0195 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0027 | 0.0223 | 0.2241 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0057 | 0.0588 | 0.7678 |
Schistosoma mansoni | cpg binding protein | 0.0029 | 0.0256 | 0.0513 |
Brugia malayi | hypothetical protein | 0.0125 | 0.1425 | 0.3597 |
Trypanosoma cruzi | CAAX prenyl protease 2, putative | 0.0187 | 0.2182 | 1 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0032 | 0.0292 | 0.0736 |
Echinococcus granulosus | MAM | 0.0016 | 0.0099 | 0.0199 |
Trypanosoma cruzi | peptidase with unknown catalytic mechanism (family U48) | 0.0187 | 0.2182 | 1 |
Onchocerca volvulus | 0.0015 | 0.0085 | 0.0184 | |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0026 | 0.0213 | 0.4285 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0026 | 0.0213 | 0.4285 |
Toxoplasma gondii | NAC domain-containing protein | 0.0036 | 0.0334 | 0.3898 |
Brugia malayi | hypothetical protein | 0.0037 | 0.0347 | 0.0876 |
Onchocerca volvulus | 0.0049 | 0.05 | 0.1234 | |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.001 | 0.0025 | 0.0049 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.001 | 0.0025 | 0.0062 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0094 | 0.1042 | 0.6201 |
Plasmodium falciparum | thioredoxin reductase | 0.0041 | 0.04 | 1 |
Giardia lamblia | Hypothetical protein | 0.0187 | 0.2182 | 0.5493 |
Loa Loa (eye worm) | glycogen phosphorylase | 0.0333 | 0.3961 | 1 |
Onchocerca volvulus | Huntingtin homolog | 0.0125 | 0.1425 | 0.3577 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0014 | 0.0072 | 0.0072 |
Plasmodium falciparum | protease, putative | 0.0039 | 0.037 | 0.9082 |
Mycobacterium tuberculosis | Probable conserved integral membrane protein | 0.0039 | 0.037 | 0.2038 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0026 | 0.0213 | 0.0665 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0032 | 0.0292 | 0.0292 |
Brugia malayi | Thioredoxin reductase | 0.0041 | 0.04 | 0.1009 |
Brugia malayi | Cell death specification protein 2 | 0.0009 | 0.0012 | 0.0031 |
Trypanosoma brucei | CAAX amino terminal protease, putative | 0.0187 | 0.2182 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0012 | 0.0031 |
Brugia malayi | SEA domain containing protein | 0.0015 | 0.0085 | 0.0215 |
Onchocerca volvulus | 0.0029 | 0.0256 | 0.0618 | |
Trichomonas vaginalis | conserved hypothetical protein | 0.0036 | 0.0334 | 0.0748 |
Echinococcus granulosus | transcription factor btf3 | 0.0036 | 0.0334 | 0.0669 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0019 | 0.0133 | 0.0287 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.001 | 0.0025 | 0.0062 |
Echinococcus multilocularis | dnaJ subfamily B | 0.0418 | 0.4994 | 0.4994 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0025 | 0.0062 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription factor | 0.0009 | 0.0012 | 0.0012 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.0748 | 0.1888 |
Loa Loa (eye worm) | peptidase family M48 containing protein | 0.0069 | 0.0744 | 0.1878 |
Echinococcus granulosus | dnaJ subfamily B | 0.0418 | 0.4994 | 1 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0026 | 0.0213 | 0.2089 |
Brugia malayi | Protein kinase domain containing protein | 0.0016 | 0.0099 | 0.025 |
Echinococcus multilocularis | ubiquitin carboxyl terminal hydrolase 8 | 0.0038 | 0.0359 | 0.0359 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.001 | 0.0025 | 0.0049 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0359 | 0.0907 |
Echinococcus multilocularis | transcription factor btf3 | 0.0036 | 0.0334 | 0.0334 |
Schistosoma mansoni | transcriptional factor nfil3/e4bp4 | 0.0009 | 0.0012 | 0.0025 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0014 | 0.0072 | 0.0145 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0019 | 0.0133 | 0.2038 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0012 | 0.0031 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0014 | 0.0072 | 0.0145 |
Brugia malayi | Ubiquitin carboxyl-terminal hydrolase family protein | 0.0038 | 0.0359 | 0.0907 |
Toxoplasma gondii | CAAX amino terminal protease family protein | 0.0039 | 0.037 | 0.4427 |
Mycobacterium tuberculosis | Probable integral membrane protein | 0.0039 | 0.037 | 0.2038 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.0333 | 0.3961 | 1 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0032 | 0.0292 | 0.0736 |
Echinococcus multilocularis | ubiquitin specific protease 41 | 0.0038 | 0.0359 | 0.0359 |
Entamoeba histolytica | ubiquitin carboxyl-terminal hydrolase domain containing protein | 0.0038 | 0.0359 | 0.0879 |
Brugia malayi | hypothetical protein | 0.0026 | 0.0213 | 0.0537 |
Schistosoma mansoni | thyrotroph embryonic factor related | 0.0009 | 0.0012 | 0.0025 |
Brugia malayi | MH2 domain containing protein | 0.0122 | 0.1386 | 0.3499 |
Trypanosoma cruzi | metallo- peptidase, Clan M- Family M48 | 0.0069 | 0.0744 | 0.3185 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.001 | 0.0025 | 0.0049 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0027 | 0.0223 | 0.0446 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.001 | 0.0025 | 0.0062 |
Trichomonas vaginalis | set domain proteins, putative | 0.0206 | 0.2417 | 0.6061 |
Entamoeba histolytica | glycogenphosphorylase, putative | 0.0144 | 0.1655 | 0.416 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0099 | 0.025 |
Plasmodium falciparum | basic transcription factor 3b, putative | 0.0036 | 0.0334 | 0.7997 |
Mycobacterium tuberculosis | Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot | 0.0014 | 0.0072 | 0.0195 |
Echinococcus multilocularis | caax prenyl protease 1 | 0.0069 | 0.0744 | 0.0744 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0027 | 0.0223 | 0.0223 |
Echinococcus multilocularis | X box binding protein 1 | 0.0294 | 0.3488 | 0.3488 |
Giardia lamblia | Glycogen phosphorylase | 0.0333 | 0.3961 | 1 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0063 | 0.0669 | 0.134 |
Plasmodium vivax | basic transcription factor 3b, putative | 0.0036 | 0.0334 | 0.7997 |
Schistosoma mansoni | ap endonuclease | 0.0019 | 0.0133 | 0.0266 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.001 | 0.002 | 0.0049 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription factor | 0.0009 | 0.0012 | 0.0025 |
Plasmodium vivax | glutathione reductase, putative | 0.0041 | 0.04 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.001 | 0.0025 | 0.0049 |
Schistosoma mansoni | transcription factor btf3 | 0.0036 | 0.0334 | 0.0669 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0026 | 0.0213 | 0.4285 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0094 | 0.1042 | 0.6201 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0019 | 0.0133 | 0.0266 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0025 | 0.0062 |
Schistosoma mansoni | hypothetical protein | 0.007 | 0.0748 | 0.1497 |
Brugia malayi | Pre-SET motif family protein | 0.0027 | 0.0223 | 0.0563 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0012 | 0.0031 |
Entamoeba histolytica | CAAX amino terminal protease family | 0.0039 | 0.037 | 0.0905 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0014 | 0.0072 | 0.3419 |
Schistosoma mansoni | hypothetical protein | 0.0009 | 0.0012 | 0.0025 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0041 | 0.04 | 1 |
Onchocerca volvulus | 0.0016 | 0.0099 | 0.022 | |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.0347 | 0.0847 |
Echinococcus multilocularis | Ataxin 2, N terminal,domain containing protein | 0.0012 | 0.004 | 0.004 |
Leishmania major | trypanothione reductase | 0.0041 | 0.04 | 0.1553 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0223 | 0.0563 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0104 | 0.1169 | 0.6991 |
Entamoeba histolytica | CAAX amino terminal protease family | 0.0039 | 0.037 | 0.0905 |
Echinococcus granulosus | ccaat enhancer binding protein delta | 0.0009 | 0.0012 | 0.0025 |
Echinococcus multilocularis | Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 | 0.0038 | 0.0359 | 0.0359 |
Trichomonas vaginalis | glycogen phosphorylase, putative | 0.0333 | 0.3961 | 1 |
Onchocerca volvulus | 0.0015 | 0.0085 | 0.0184 | |
Echinococcus multilocularis | Glycosyl transferase, family 35 | 0.0333 | 0.3961 | 0.3961 |
Entamoeba histolytica | CAAX prenyl protease family | 0.0187 | 0.2182 | 0.5493 |
Echinococcus granulosus | Ataxin 2 N terminaldomain containing protein | 0.0012 | 0.004 | 0.0079 |
Trichomonas vaginalis | Clan U, family U48, CaaX prenyl peptidase 2-like | 0.0187 | 0.2182 | 0.5461 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0047 | 0.0468 | 0.0468 |
Plasmodium vivax | SET domain protein, putative | 0.0027 | 0.0223 | 0.4597 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.0144 | 0.1655 | 0.416 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.001 | 0.0025 | 0.0049 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0085 | 0.017 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.0019 | 0.0133 | 0.0571 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.0334 | 0.0815 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0104 | 0.1169 | 0.6991 |
Schistosoma mansoni | hypothetical protein | 0.0049 | 0.05 | 0.1 |
Entamoeba histolytica | CAAX prenyl protease, putative | 0.0069 | 0.0744 | 0.1853 |
Schistosoma mansoni | hypothetical protein | 0.0294 | 0.3488 | 0.6984 |
Loa Loa (eye worm) | cell death specification protein 2 | 0.0009 | 0.0012 | 0.0031 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0102 | 0.1141 | 0.288 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0019 | 0.0133 | 0.0336 |
Schistosoma mansoni | ubiquitin-specific peptidase 2 (C19 family) | 0.0038 | 0.0359 | 0.072 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.001 | 0.0025 | 0.0062 |
Onchocerca volvulus | Bile acid receptor homolog | 0.001 | 0.0025 | 0.0031 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0041 | 0.04 | 0.0801 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0019 | 0.0133 | 0.0235 |
Leishmania major | basic transcription factor 3a, putative | 0.0036 | 0.0334 | 0.1242 |
Schistosoma mansoni | glycogen phosphorylase | 0.0333 | 0.3961 | 0.7932 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0019 | 0.0133 | 0.1851 |
Trichomonas vaginalis | Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase | 0.0038 | 0.0359 | 0.0812 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0039 | 0.037 | 0.2038 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0104 | 0.1169 | 0.6991 |
Schistosoma mansoni | nuclear hormone receptor | 0.001 | 0.0025 | 0.0049 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.001 | 0.0025 | 0.0025 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.0347 | 0.0847 |
Trichomonas vaginalis | mercuric reductase, putative | 0.0014 | 0.0072 | 0.008 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0047 | 0.0468 | 0.0468 |
Brugia malayi | carbohydrate phosphorylase | 0.0333 | 0.3961 | 1 |
Plasmodium vivax | protease, putative | 0.0039 | 0.037 | 0.9082 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.001 | 0.0025 | 0.0062 |
Loa Loa (eye worm) | ICD-1 protein | 0.0036 | 0.0334 | 0.0844 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.001 | 0.0025 | 0.0062 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0032 | 0.0292 | 0.0584 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0019 | 0.0133 | 0.0133 |
Echinococcus granulosus | protocadherin 11 | 0.0009 | 0.0012 | 0.0025 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0025 | 0.0203 | 0.0407 |
Trypanosoma brucei | transcription factor BTF3, putative | 0.0036 | 0.0334 | 0.1242 |
Echinococcus granulosus | Glycosyl transferase family 35 | 0.0333 | 0.3961 | 0.7932 |
Schistosoma mansoni | ap endonuclease | 0.0019 | 0.0133 | 0.0266 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0122 | 0.1386 | 0.3499 |
Echinococcus granulosus | FTZ F1 alpha | 0.001 | 0.0025 | 0.0049 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.0292 | 0.0584 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0019 | 0.0133 | 0.0287 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0027 | 0.0223 | 0.0446 |
Echinococcus granulosus | glycogen phosphorylase | 0.0333 | 0.3961 | 0.7932 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.001 | 0.0025 | 0.0062 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0102 | 0.1141 | 0.288 |
Brugia malayi | hypothetical protein | 0.0016 | 0.0099 | 0.025 |
Brugia malayi | hypothetical protein | 0.0009 | 0.0012 | 0.0031 |
Leishmania major | ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative | 0.0038 | 0.0359 | 0.1361 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.0019 | 0.0133 | 0.0305 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.0144 | 0.1655 | 0.416 |
Trypanosoma cruzi | transcription factor btf3, putative | 0.0036 | 0.0334 | 0.1242 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0012 | 0.0031 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0094 | 0.1042 | 0.887 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0019 | 0.0133 | 0.0571 |
Echinococcus multilocularis | cyclic AMP responsive element binding protein | 0.0009 | 0.0012 | 0.0012 |
Trypanosoma cruzi | CAAX prenyl protease 1, putative | 0.0069 | 0.0744 | 0.3185 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.001 | 0.0025 | 0.0049 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.001 | 0.0025 | 0.0049 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0047 | 0.0468 | 0.1183 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0027 | 0.0223 | 0.0446 |
Onchocerca volvulus | 0.0206 | 0.2417 | 0.609 | |
Echinococcus granulosus | ubiquitin specific protease 41 | 0.0038 | 0.0359 | 0.072 |
Brugia malayi | ecdysteroid receptor | 0.001 | 0.0025 | 0.0062 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0047 | 0.0468 | 0.0938 |
Echinococcus granulosus | caax prenyl protease 1 | 0.0069 | 0.0744 | 0.149 |
Schistosoma mansoni | par domain protein | 0.0009 | 0.0012 | 0.0025 |
Onchocerca volvulus | Glycogen phosphorylase homolog | 0.0333 | 0.3961 | 1 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.001 | 0.0025 | 0.0062 |
Schistosoma mansoni | hypothetical protein | 0.0012 | 0.004 | 0.0079 |
Loa Loa (eye worm) | hypothetical protein | 0.0125 | 0.1425 | 0.3597 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.001 | 0.0025 | 0.0049 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Luciferase activity (functional) | = 160000 RLU 10s-1 | Compound was tested for luciferase activity in Monkey CV1 Cell Lines | ChEMBL. | 9457245 |
Luciferase activity (functional) | = 5400000 RLU 10s-1 | Luciferase activity in mouse fibroblasts NIH3T3 cells. | ChEMBL. | 9457245 |
Luciferase activity (functional) | = 5400000 RLU 10s-1 | Luciferase activity in mouse fibroblasts NIH3T3 cells. | ChEMBL. | 9457245 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.