Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Entamoeba histolytica | hypothetical protein | 0.007 | 0.0874 | 1 |
Brugia malayi | Cytochrome P450 family protein | 0.0017 | 0.0114 | 0.0114 |
Schistosoma mansoni | thyroid hormone receptor | 0.0018 | 0.0136 | 0.0229 |
Leishmania major | acetoin dehydrogenase e3 component-like protein | 0.0017 | 0.0121 | 0.0041 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0018 | 0.0136 | 0.0229 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0113 | 0.1471 | 0.1374 |
Brugia malayi | beta-NAC-like protein | 0.0035 | 0.0369 | 0.0369 |
Mycobacterium tuberculosis | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase BioA | 0.0064 | 0.0781 | 0.0676 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0017 | 0.0121 | 0.0041 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.001 | 0.0015 | 0.0015 |
Schistosoma mansoni | thyroid hormone receptor | 0.0018 | 0.0136 | 0.0229 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.003 | 0.0303 | 0.1953 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.001 | 0.0015 | 0.0025 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.052 | 0.0878 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0035 | 0.0369 | 0.3736 |
Loa Loa (eye worm) | glutathione reductase | 0.0049 | 0.0577 | 0.372 |
Trichomonas vaginalis | acetylornithine aminotransferase, putative | 0.0064 | 0.0781 | 0.8531 |
Schistosoma mansoni | intermediate filament proteins | 0.0027 | 0.0257 | 0.0434 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.002 | 0.0157 | 0.021 |
Schistosoma mansoni | hypothetical protein | 0.0177 | 0.238 | 0.4023 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, mitochondrial, putative | 0.0017 | 0.0121 | 0.1002 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0035 | 0.0369 | 0.3736 |
Mycobacterium tuberculosis | Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) | 0.0166 | 0.2228 | 0.214 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0369 | 0.3886 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.001 | 0.0015 | 0.0015 |
Mycobacterium ulcerans | hypothetical protein | 0.0064 | 0.0781 | 0.0674 |
Echinococcus granulosus | ornithine aminotransferase | 0.0064 | 0.0781 | 0.132 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0041 | 0.0455 | 0.4746 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0047 | 0.0305 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0015 | 0.0094 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0018 | 0.0136 | 0.0229 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.002 | 0.0157 | 0.021 |
Loa Loa (eye worm) | CHromoDomain protein family member | 0.0014 | 0.0071 | 0.0461 |
Mycobacterium ulcerans | ornithine aminotransferase RocD1 and RocD2 | 0.0064 | 0.0781 | 0.0674 |
Echinococcus multilocularis | geminin | 0.0177 | 0.238 | 0.4023 |
Onchocerca volvulus | 0.0027 | 0.0257 | 0.5141 | |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0013 | 0.0057 | 0.0096 |
Trypanosoma cruzi | transcription factor btf3, putative | 0.0035 | 0.0369 | 0.1212 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0018 | 0.0136 | 0.0136 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0017 | 0.0114 | 0.001 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0136 | 0.0874 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0054 | 0.035 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0017 | 0.0121 | 0.0041 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0015 | 0.0094 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0136 | 0.0874 |
Schistosoma mansoni | cpg binding protein | 0.0032 | 0.0327 | 0.0553 |
Mycobacterium ulcerans | NAD-dependent aldehyde dehydrogenase AldA | 0.0028 | 0.0276 | 0.0164 |
Brugia malayi | CHD4 protein | 0.0014 | 0.0071 | 0.0071 |
Echinococcus granulosus | NADP dependent isocitrate dehydrogenase | 0.0017 | 0.0112 | 0.019 |
Brugia malayi | Type III restriction enzyme, res subunit family protein | 0.0012 | 0.0047 | 0.0047 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0113 | 0.1471 | 0.1374 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0113 | 0.1471 | 0.1374 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0017 | 0.0121 | 0.0041 |
Trichomonas vaginalis | chromobox protein, putative | 0.0044 | 0.0499 | 0.5254 |
Entamoeba histolytica | hypothetical protein | 0.007 | 0.0874 | 1 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0019 | 0.0143 | 0.1117 |
Wolbachia endosymbiont of Brugia malayi | acetylornithine transaminase protein | 0.0064 | 0.0781 | 1 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0125 | 0.1649 | 0.1554 |
Mycobacterium ulcerans | NAD-dependent aldehyde dehydrogenase AldA | 0.0028 | 0.0276 | 0.0164 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0018 | 0.0136 | 0.0136 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0009 | 0.0008 | 0.0008 |
Brugia malayi | MH2 domain containing protein | 0.0118 | 0.1551 | 0.1551 |
Brugia malayi | glutathione reductase | 0.0049 | 0.0577 | 0.0577 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0017 | 0.0121 | 0.0204 |
Mycobacterium tuberculosis | Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot | 0.0017 | 0.0121 | 0.0009 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0049 | 0.0577 | 0.2196 |
Loa Loa (eye worm) | helicase | 0.0012 | 0.0047 | 0.0305 |
Plasmodium vivax | glutathione reductase, putative | 0.0049 | 0.0577 | 0.7219 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase | 0.0017 | 0.0121 | 0.0007 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.052 | 0.0878 |
Echinococcus granulosus | geminin | 0.0177 | 0.238 | 0.4023 |
Plasmodium falciparum | basic transcription factor 3b, putative | 0.0035 | 0.0369 | 0.4379 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0018 | 0.0136 | 0.0136 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.001 | 0.0015 | 0.0025 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0018 | 0.0136 | 0.0136 |
Echinococcus multilocularis | lamin | 0.0027 | 0.0257 | 0.0434 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase, LpdB | 0.0017 | 0.0121 | 0.0007 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0018 | 0.0136 | 0.0136 |
Brugia malayi | hypothetical protein | 0.001 | 0.0015 | 0.0015 |
Schistosoma mansoni | ap endonuclease | 0.002 | 0.0157 | 0.0265 |
Mycobacterium ulcerans | glutamate-1-semialdehyde aminotransferase | 0.0064 | 0.0781 | 0.0674 |
Leishmania major | basic transcription factor 3a, putative | 0.0035 | 0.0369 | 0.1212 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0018 | 0.0136 | 0.0229 |
Onchocerca volvulus | 0.0032 | 0.0331 | 0.6629 | |
Brugia malayi | chromobox protein homolog 3 | 0.0041 | 0.0455 | 0.0455 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0018 | 0.0136 | 0.0229 |
Echinococcus multilocularis | succinate semialdehyde dehydrogenase | 0.0028 | 0.0276 | 0.0467 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0018 | 0.0136 | 0.2714 |
Trypanosoma brucei | cytochrome P450, putative | 0.0017 | 0.0114 | 0.001 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0018 | 0.0136 | 0.0229 |
Mycobacterium ulcerans | flavoprotein disulfide reductase | 0.0017 | 0.0121 | 0.0007 |
Schistosoma mansoni | cpg binding protein | 0.003 | 0.0303 | 0.0512 |
Schistosoma mansoni | chromobox protein | 0.0012 | 0.0047 | 0.008 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0047 | 0.0305 |
Leishmania major | cytochrome p450-like protein | 0.0017 | 0.0114 | 0.001 |
Schistosoma mansoni | ap endonuclease | 0.002 | 0.0157 | 0.0265 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.002 | 0.0157 | 0.021 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0018 | 0.0136 | 0.0229 |
Trichomonas vaginalis | chromobox protein, putative | 0.0044 | 0.0499 | 0.5254 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.002 | 0.0157 | 0.0045 |
Echinococcus granulosus | intermediate filament protein | 0.0027 | 0.0257 | 0.0434 |
Brugia malayi | hypothetical protein | 0.007 | 0.0874 | 0.0874 |
Leishmania major | aldehyde dehydrogenase, putative | 0.0028 | 0.0276 | 0.0774 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0035 | 0.0369 | 0.3736 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0016 | 0.0099 | 0.0599 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0125 | 0.1649 | 0.1554 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0049 | 0.0577 | 0.7219 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0015 | 0.0092 | 0.0518 |
Echinococcus granulosus | chromobox protein 1 | 0.0073 | 0.0907 | 0.1534 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0049 | 0.0577 | 0.0975 |
Schistosoma mansoni | coup transcription factor | 0.0018 | 0.0136 | 0.0229 |
Echinococcus multilocularis | chromodomain helicase DNA binding protein 1 | 0.0012 | 0.0047 | 0.008 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0113 | 0.1471 | 0.1374 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0018 | 0.0136 | 0.0229 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0018 | 0.0136 | 0.0874 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0014 | 0.0081 | 0.0081 |
Schistosoma mansoni | NADP-specific isocitrate dehydrogenase | 0.0017 | 0.0112 | 0.019 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0136 | 0.0874 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.052 | 0.0878 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0029 | 0.0287 | 0.2789 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0017 | 0.0121 | 0.0041 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0018 | 0.0136 | 0.0874 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0018 | 0.0136 | 0.0229 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0019 | 0.0143 | 0.1117 |
Trichomonas vaginalis | chromobox protein, putative | 0.0073 | 0.0907 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0054 | 0.0642 | 0.1086 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0455 | 0.2937 |
Mycobacterium leprae | PROBABLE GLUTAMATE-1-SEMIALDEHYDE 2,1-AMINOMUTASE HEML (GSA) (GLUTAMATE-1-SEMIALDEHYDE AMINOTRANSFERASE) (GSA-AT) | 0.0064 | 0.0781 | 0.3679 |
Trypanosoma brucei | trypanothione reductase | 0.0049 | 0.0577 | 0.2196 |
Loa Loa (eye worm) | ICD-1 protein | 0.0035 | 0.0369 | 0.2377 |
Echinococcus multilocularis | Aminotransferase class III | 0.0064 | 0.0781 | 0.132 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0018 | 0.0136 | 0.0229 |
Leishmania major | 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein | 0.0017 | 0.0121 | 0.0041 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0017 | 0.0121 | 0.0041 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.002 | 0.0157 | 0.0265 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0017 | 0.0114 | 0.0737 |
Schistosoma mansoni | transcription factor btf3 | 0.0035 | 0.0369 | 0.0623 |
Schistosoma mansoni | chromodomain helicase DNA binding protein | 0.0014 | 0.0071 | 0.0121 |
Echinococcus granulosus | chromodomain helicase DNA binding protein 1 | 0.0012 | 0.0047 | 0.008 |
Mycobacterium ulcerans | cytochrome P450 51B1 Cyp51B1 | 0.0166 | 0.2228 | 0.2138 |
Brugia malayi | Associated with TFs and helicases family protein | 0.0012 | 0.0047 | 0.0047 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0017 | 0.0121 | 0.0041 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0009 | 0.001 | 0.0017 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0017 | 0.0121 | 0.0041 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0118 | 0.1551 | 1 |
Trypanosoma brucei | dihydrolipoyl dehydrogenase | 0.0017 | 0.0121 | 0.0041 |
Echinococcus multilocularis | chromobox protein 1 | 0.0073 | 0.0907 | 0.1534 |
Onchocerca volvulus | 0.0018 | 0.0136 | 0.2714 | |
Mycobacterium tuberculosis | Probable ornithine aminotransferase (N-terminus part) RocD1 (ornithine--oxo-acid aminotransferase) | 0.0064 | 0.0781 | 0.0676 |
Plasmodium falciparum | isocitrate dehydrogenase [NADP], mitochondrial | 0.0017 | 0.0112 | 0.0884 |
Plasmodium falciparum | thioredoxin reductase | 0.0049 | 0.0577 | 0.7219 |
Trichomonas vaginalis | mercuric reductase, putative | 0.0017 | 0.0121 | 0.0855 |
Schistosoma mansoni | hypothetical protein | 0.0177 | 0.238 | 0.4023 |
Brugia malayi | intermediate filament protein | 0.0027 | 0.0257 | 0.0257 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0047 | 0.0305 |
Echinococcus granulosus | chromodomain helicase DNA binding protein 4 | 0.0014 | 0.0071 | 0.0121 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.001 | 0.0015 | 0.0025 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0019 | 0.0143 | 0.1117 |
Mycobacterium leprae | Probable Acetylornithine aminotransferase ArgD | 0.0064 | 0.0781 | 0.3679 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0017 | 0.0112 | 0.019 |
Echinococcus granulosus | cytoplasmic intermediate filament protein | 0.0013 | 0.0061 | 0.0104 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0018 | 0.0136 | 0.0874 |
Brugia malayi | Isocitrate dehydrogenase | 0.0017 | 0.0112 | 0.0112 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.002 | 0.0157 | 1 |
Echinococcus multilocularis | isocitrate dehydrogenase 2 (NADP+) | 0.0017 | 0.0112 | 0.019 |
Brugia malayi | hypothetical protein | 0.0012 | 0.0047 | 0.0047 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0049 | 0.0577 | 0.372 |
Echinococcus granulosus | Chromobox protein 3 | 0.0012 | 0.0047 | 0.008 |
Brugia malayi | Cytochrome P450 family protein | 0.0017 | 0.0114 | 0.0114 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0018 | 0.0136 | 0.0229 |
Schistosoma mansoni | cpg binding protein | 0.0032 | 0.0327 | 0.0553 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0018 | 0.0136 | 0.0229 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0019 | 0.0143 | 0.1117 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0125 | 0.1649 | 1 |
Plasmodium vivax | isocitrate dehydrogenase [NADP], mitochondrial, putative | 0.0017 | 0.0112 | 0.0884 |
Onchocerca volvulus | 0.0013 | 0.0057 | 0.1133 | |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.025 | 0.161 |
Echinococcus multilocularis | lamin dm0 | 0.0027 | 0.0257 | 0.0434 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0061 | 0.0395 |
Brugia malayi | ecdysteroid receptor | 0.0018 | 0.0136 | 0.0136 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0018 | 0.0136 | 0.0229 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, apicoplast | 0.0017 | 0.0121 | 0.1002 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase, point mutation | 0.0017 | 0.0121 | 0.0041 |
Trichomonas vaginalis | ap endonuclease, putative | 0.002 | 0.0157 | 0.1271 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.001 | 0.0015 | 0.0094 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0016 | 0.0099 | 0.0599 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0018 | 0.0136 | 0.0136 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0044 | 0.0499 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0047 | 0.0305 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0017 | 0.0112 | 0.0884 |
Schistosoma mansoni | lamin | 0.0027 | 0.0257 | 0.0434 |
Plasmodium falciparum | glutathione reductase | 0.0049 | 0.0577 | 0.7219 |
Echinococcus multilocularis | transcription factor btf3 | 0.0035 | 0.0369 | 0.0623 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0018 | 0.0136 | 0.0136 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0047 | 0.0305 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0018 | 0.0136 | 0.0874 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.002 | 0.0157 | 0.0265 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.002 | 0.0157 | 0.1322 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0017 | 0.0121 | 0.0041 |
Brugia malayi | SET domain containing protein | 0.0013 | 0.0057 | 0.0057 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0008 | 0.0054 |
Entamoeba histolytica | hypothetical protein | 0.007 | 0.0874 | 1 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0017 | 0.0121 | 0.0041 |
Brugia malayi | Succinate semialdehyde dehydrogenase, mitochondrial precursor | 0.0028 | 0.0276 | 0.0276 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0017 | 0.0112 | 0.019 |
Trypanosoma brucei | Lanosterol 14-alpha demethylase | 0.0166 | 0.2228 | 1 |
Loa Loa (eye worm) | isocitrate dehydrogenase | 0.0017 | 0.0112 | 0.0723 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.002 | 0.0157 | 0.1489 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0017 | 0.0112 | 0.019 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0018 | 0.0136 | 0.0874 |
Schistosoma mansoni | chromobox protein | 0.0073 | 0.0907 | 0.1534 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0018 | 0.0136 | 0.0136 |
Brugia malayi | M-phase phosphoprotein, mpp8 | 0.0012 | 0.0047 | 0.0047 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0118 | 0.1551 | 1 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0018 | 0.0136 | 0.2714 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0045 | 0.052 | 0.335 |
Echinococcus granulosus | FTZ F1 alpha | 0.0018 | 0.0136 | 0.0229 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0054 | 0.035 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.002 | 0.0157 | 0.101 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0018 | 0.0136 | 0.0229 |
Schistosoma mansoni | ornithine--oxo-acid transaminase | 0.0064 | 0.0781 | 0.132 |
Trypanosoma cruzi | transcription factor btf3, putative | 0.0035 | 0.0369 | 0.1212 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0331 | 0.2134 |
Brugia malayi | steroid hormone receptor | 0.0018 | 0.0136 | 0.0136 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0041 | 0.0455 | 0.9123 |
Mycobacterium leprae | PROBABLE ADENOSYLMETHIONINE-8-AMINO-7-OXONONANOATE AMINOTRANSFERASE BIOA | 0.0064 | 0.0781 | 0.3679 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0018 | 0.0136 | 0.0229 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0017 | 0.0114 | 0.001 |
Plasmodium falciparum | glutathione reductase | 0.0017 | 0.0121 | 0.1002 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.007 | 0.0874 | 0.1477 |
Entamoeba histolytica | transcription factor BTF3, putative | 0.0035 | 0.0369 | 0.3886 |
Leishmania major | trypanothione reductase | 0.0049 | 0.0577 | 0.2196 |
Brugia malayi | nuclear receptor NHR-88 | 0.0018 | 0.0136 | 0.0136 |
Schistosoma mansoni | hypothetical protein | 0.0012 | 0.0047 | 0.008 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0018 | 0.0136 | 0.0229 |
Brugia malayi | hypothetical protein | 0.001 | 0.0015 | 0.0015 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0018 | 0.0136 | 0.0136 |
Onchocerca volvulus | 0.0012 | 0.0047 | 0.0948 | |
Loa Loa (eye worm) | CYP4Cod1 | 0.0017 | 0.0114 | 0.0737 |
Echinococcus multilocularis | chromobox protein 1 | 0.0073 | 0.0907 | 0.1534 |
Trichomonas vaginalis | ap endonuclease, putative | 0.002 | 0.0157 | 0.1271 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0019 | 0.0143 | 0.1117 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0018 | 0.0136 | 0.0874 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0136 | 0.0874 |
Schistosoma mansoni | chromobox protein-related (chromobox 1) (heterochromatin 1) | 0.0012 | 0.0047 | 0.008 |
Mycobacterium ulcerans | 4-aminobutyrate aminotransferase | 0.0064 | 0.0781 | 0.0674 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0017 | 0.0121 | 0.0041 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.002 | 0.0157 | 0.0043 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0019 | 0.0143 | 0.1117 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0064 | 0.0778 | 0.1315 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.007 | 0.0874 | 0.1477 |
Echinococcus granulosus | dnaJ subfamily B | 0.0427 | 0.5916 | 1 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0045 | 0.052 | 0.052 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0018 | 0.0136 | 0.0229 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0018 | 0.0136 | 0.0229 |
Mycobacterium leprae | Probable 4-aminobutyrate aminotransferase GabT (GAMMA-AMINO-N-BUTYRATE TRANSAMINASE) (GABA TRANSAMINASE) (GLUTAMATE:SUCCINIC SEM | 0.0064 | 0.0781 | 0.3679 |
Mycobacterium tuberculosis | Probable L-lysine-epsilon aminotransferase Lat (L-lysine aminotransferase) (lysine 6-aminotransferase) | 0.0716 | 1 | 1 |
Echinococcus multilocularis | succinate semialdehyde dehydrogenase | 0.0028 | 0.0276 | 0.0467 |
Echinococcus multilocularis | chromobox protein 2 | 0.0012 | 0.0047 | 0.008 |
Brugia malayi | isocitrate dehydrogenase | 0.0017 | 0.0112 | 0.0112 |
Toxoplasma gondii | thioredoxin reductase | 0.0049 | 0.0577 | 0.7219 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0257 | 0.1655 |
Mycobacterium tuberculosis | Probable reductase | 0.0113 | 0.1471 | 0.1374 |
Onchocerca volvulus | 0.0027 | 0.0257 | 0.5141 | |
Trichomonas vaginalis | conserved hypothetical protein | 0.0029 | 0.0287 | 0.2789 |
Onchocerca volvulus | 0.003 | 0.0303 | 0.6067 | |
Toxoplasma gondii | NAC domain-containing protein | 0.0035 | 0.0369 | 0.4379 |
Echinococcus multilocularis | isocitrate dehydrogenase | 0.0017 | 0.0112 | 0.019 |
Trypanosoma brucei | transcription factor BTF3, putative | 0.0035 | 0.0369 | 0.1212 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0017 | 0.0112 | 0.0884 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0018 | 0.0136 | 0.0229 |
Echinococcus granulosus | succinate semialdehyde dehydrogenase | 0.0028 | 0.0276 | 0.0467 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0017 | 0.0121 | 0.0041 |
Mycobacterium ulcerans | acetylornithine aminotransferase | 0.0064 | 0.0781 | 0.0674 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0018 | 0.0136 | 0.0136 |
Trypanosoma cruzi | aldehyde dehydrogenase, putative | 0.0028 | 0.0276 | 0.0774 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.002 | 0.0157 | 1 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein | 0.0013 | 0.0057 | 0.0057 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0018 | 0.0136 | 0.0136 |
Echinococcus granulosus | chromobox protein 2 | 0.0012 | 0.0047 | 0.008 |
Trichomonas vaginalis | chromobox protein, putative | 0.0073 | 0.0907 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0018 | 0.0136 | 0.0874 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0049 | 0.0577 | 0.047 |
Plasmodium vivax | basic transcription factor 3b, putative | 0.0035 | 0.0369 | 0.4379 |
Mycobacterium tuberculosis | Succinate-semialdehyde dehydrogenase [NADP+] dependent (SSDH) GabD1 | 0.0028 | 0.0276 | 0.0166 |
Brugia malayi | Thioredoxin reductase | 0.0049 | 0.0577 | 0.0577 |
Toxoplasma gondii | ornithine aminotransferase, mitochondrial precursor, putative | 0.0064 | 0.0781 | 1 |
Loa Loa (eye worm) | histone methyltransferase | 0.0009 | 0.001 | 0.0065 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0049 | 0.0577 | 0.0975 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0113 | 0.1471 | 0.8706 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.002 | 0.0157 | 0.0157 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0125 | 0.1649 | 0.1554 |
Mycobacterium ulcerans | adenosylmethionine-8-amino-7-oxononanoate aminotransferase | 0.0064 | 0.0781 | 0.0674 |
Onchocerca volvulus | 0.0012 | 0.0047 | 0.0948 | |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0018 | 0.0136 | 0.0136 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.007 | 0.0874 | 0.1477 |
Loa Loa (eye worm) | intermediate filament protein | 0.0027 | 0.0257 | 0.1655 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.052 | 0.0878 |
Echinococcus multilocularis | chromodomain helicase DNA binding protein 4 | 0.0014 | 0.0071 | 0.0121 |
Trichomonas vaginalis | glutathione reductase, putative | 0.0017 | 0.0121 | 0.0855 |
Chlamydia trachomatis | glutamate-1-semialdehyde-2,1-aminomutase | 0.0064 | 0.0781 | 1 |
Trypanosoma brucei | aldehyde dehydrogenase, putative | 0.0028 | 0.0276 | 0.0774 |
Echinococcus granulosus | lamin dm0 | 0.0027 | 0.0257 | 0.0434 |
Schistosoma mansoni | hypothetical protein | 0.0427 | 0.5916 | 1 |
Trypanosoma cruzi | Lanosterol 14-alpha demethylase | 0.0166 | 0.2228 | 1 |
Brugia malayi | CXXC zinc finger family protein | 0.003 | 0.0303 | 0.0303 |
Schistosoma mansoni | chromobox protein | 0.0012 | 0.0047 | 0.008 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0017 | 0.0121 | 0.0041 |
Echinococcus multilocularis | Chromobox protein 3 | 0.0012 | 0.0047 | 0.008 |
Toxoplasma gondii | NADPH-glutathione reductase | 0.0017 | 0.0121 | 0.1002 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0018 | 0.0136 | 0.0229 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0018 | 0.0136 | 0.0229 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0276 | 0.178 |
Mycobacterium ulcerans | L-lysine aminotransferase | 0.0716 | 1 | 1 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.002 | 0.0157 | 0.0541 |
Brugia malayi | Heterochromatin protein 1 | 0.0073 | 0.0907 | 0.0907 |
Echinococcus multilocularis | cytoplasmic intermediate filament protein | 0.0013 | 0.0061 | 0.0104 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase NAD dependent AldA (aldehyde dehydrogenase [NAD+]) | 0.0028 | 0.0276 | 0.0166 |
Echinococcus granulosus | chromobox protein 1 | 0.0073 | 0.0907 | 0.1534 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0015 | 0.0094 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0018 | 0.0136 | 0.2714 |
Echinococcus granulosus | Chromo domain | 0.0012 | 0.0047 | 0.008 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0009 | 0.001 | 0.0017 |
Loa Loa (eye worm) | heterochromatin protein 1 | 0.0073 | 0.0907 | 0.5851 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.052 | 0.0878 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, apicoplast, putative | 0.0017 | 0.0121 | 0.1002 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0018 | 0.0136 | 0.0229 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0014 | 0.0081 | 0.0524 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0113 | 0.1471 | 0.1374 |
Echinococcus multilocularis | ornithine aminotransferase | 0.0064 | 0.0781 | 0.132 |
Brugia malayi | nuclear hormone receptor | 0.0018 | 0.0136 | 0.0136 |
Plasmodium falciparum | ornithine aminotransferase | 0.0064 | 0.0781 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.052 | 0.0878 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0018 | 0.0136 | 0.0229 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0047 | 0.0305 |
Plasmodium falciparum | thioredoxin reductase | 0.0017 | 0.0121 | 0.1002 |
Leishmania major | lanosterol 14-alpha-demethylase, putative | 0.0166 | 0.2228 | 1 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0018 | 0.0136 | 0.0136 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0136 | 0.0874 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0018 | 0.0136 | 0.0229 |
Brugia malayi | nuclear receptor RXR | 0.001 | 0.0015 | 0.0015 |
Mycobacterium ulcerans | 4-aminobutyrate aminotransferase | 0.0064 | 0.0781 | 0.0674 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.001 | 0.0015 | 0.0025 |
Toxoplasma gondii | exonuclease III APE | 0.002 | 0.0157 | 0.1489 |
Mycobacterium tuberculosis | Probable aminotransferase | 0.0064 | 0.0781 | 0.0676 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0018 | 0.0136 | 0.0874 |
Mycobacterium tuberculosis | Probable acetylornithine aminotransferase ArgD | 0.0064 | 0.0781 | 0.0676 |
Brugia malayi | Protein cec-1. | 0.0012 | 0.0047 | 0.0047 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0018 | 0.0136 | 0.0136 |
Echinococcus multilocularis | Chromo domain | 0.0012 | 0.0047 | 0.008 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0018 | 0.0136 | 0.0229 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0136 | 0.0874 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0017 | 0.0121 | 0.0121 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0017 | 0.0121 | 0.0041 |
Echinococcus multilocularis | dnaJ subfamily B | 0.0427 | 0.5916 | 1 |
Echinococcus granulosus | Aminotransferase class III | 0.0064 | 0.0781 | 0.132 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0017 | 0.0121 | 0.0204 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0276 | 0.178 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, mitochondrial | 0.0017 | 0.0121 | 0.1002 |
Mycobacterium ulcerans | succinate-semialdehyde dehydrogenase | 0.0028 | 0.0276 | 0.0164 |
Schistosoma mansoni | lamin | 0.0027 | 0.0257 | 0.0434 |
Toxoplasma gondii | NADP-dependent succinate-semialdehyde dehydrogenase | 0.0028 | 0.0276 | 0.3118 |
Entamoeba histolytica | hypothetical protein | 0.007 | 0.0874 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0015 | 0.0094 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0019 | 0.0143 | 0.1117 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.002 | 0.0157 | 0.1489 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0057 | 0.0682 | 0.8652 |
Echinococcus granulosus | lamin | 0.0027 | 0.0257 | 0.0434 |
Schistosoma mansoni | chromodomain helicase DNA binding protein | 0.0012 | 0.0047 | 0.008 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0018 | 0.0136 | 0.0136 |
Schistosoma mansoni | succinate semialdehyde dehydrogenase | 0.0028 | 0.0276 | 0.0467 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0018 | 0.0136 | 0.0229 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.052 | 0.0878 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0027 | 0.0257 | 0.0257 |
Toxoplasma gondii | pyruvate dehydrogenase complex subunit PDH-E3II | 0.0017 | 0.0121 | 0.1002 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0041 | 0.0455 | 0.4746 |
Mycobacterium tuberculosis | Probable glutamate-1-semialdehyde 2,1-aminomutase HemL (GSA) (glutamate-1-semialdehyde aminotransferase) (GSA-at) | 0.0064 | 0.0781 | 0.0676 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0017 | 0.0114 | 0.0737 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0027 | 0.0257 | 0.1655 |
Echinococcus granulosus | transcription factor btf3 | 0.0035 | 0.0369 | 0.0623 |
Echinococcus multilocularis | cpg binding protein | 0.0032 | 0.0327 | 0.0553 |
Plasmodium vivax | ornithine aminotransferase, putative | 0.0064 | 0.0781 | 1 |
Echinococcus multilocularis | musashi | 0.0027 | 0.0257 | 0.0434 |
Schistosoma mansoni | chromobox protein | 0.0073 | 0.0907 | 0.1534 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.002 | 0.0157 | 0.021 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0136 | 0.0874 |
Brugia malayi | Valyl-tRNA synthetase | 0.0012 | 0.0047 | 0.0047 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0047 | 0.0305 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0136 | 0.0874 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0017 | 0.0121 | 0.0204 |
Schistosoma mansoni | hypothetical protein | 0.007 | 0.0874 | 0.1477 |
Echinococcus granulosus | cpg binding protein | 0.0032 | 0.0327 | 0.0553 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0019 | 0.0143 | 0.1117 |
Trypanosoma cruzi | Lanosterol 14-alpha demethylase | 0.0166 | 0.2228 | 1 |
Schistosoma mansoni | chromobox protein-related (chromobox 1) (heterochromatin 1) | 0.0012 | 0.0047 | 0.008 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0015 | 0.0094 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0018 | 0.0136 | 0.0229 |
Brugia malayi | alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase | 0.0013 | 0.0057 | 0.0057 |
Echinococcus multilocularis | ornithine aminotransferase | 0.0064 | 0.0781 | 0.132 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0018 | 0.0136 | 0.0136 |
Schistosoma mansoni | nuclear hormone receptor | 0.0018 | 0.0136 | 0.0229 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
KL (binding) | = 720 nM | Binding affinity towards low-affinity site of Atrial natriuretic peptide receptor 1 of rabbit adrenal membrane | ChEMBL. | 1347790 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.