Detailed information for compound 421751

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 296.316 | Formula: C15H20O6
  • H donors: 1 H acceptors: 3 LogP: 2.37 Rotable bonds: 9
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1cc(OC)c(c(c1)C(=O)OC)CCCCC(=O)O
  • InChi: 1S/C15H20O6/c1-19-10-8-12(15(18)21-3)11(13(9-10)20-2)6-4-5-7-14(16)17/h8-9H,4-7H2,1-3H3,(H,16,17)
  • InChiKey: CWSFWXMTEAGHAT-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis beta LACTamase domain containing family member 0.0107 0.1146 0.1115
Loa Loa (eye worm) hypothetical protein 0.0107 0.1146 0.1481
Echinococcus multilocularis survival motor neuron protein 1 0.0233 0.2734 0.2709
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0042 0.0323 0.2557
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0047 0.0385 0.0768
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.002 0.0041 0.0005
Loa Loa (eye worm) hypothetical protein 0.0233 0.2734 0.3598
Leishmania major hypothetical protein, conserved 0.0026 0.0116 0.0679
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0051 0.0439 0.0426
Mycobacterium tuberculosis NADH-dependent enoyl-[acyl-carrier-protein] reductase InhA (NADH-dependent enoyl-ACP reductase) 0.0759 0.939 1
Mycobacterium ulcerans short chain dehydrogenase 0.0051 0.0439 0.0426
Mycobacterium tuberculosis Possible oxidoreductase 0.0051 0.0439 0.0426
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0054 0.0478 0.0445
Schistosoma mansoni importin beta-1 0.0057 0.0515 0.0572
Brugia malayi Latrophilin receptor protein 2 0.0047 0.0385 0.0768
Onchocerca volvulus 0.0107 0.1146 0.1948
Echinococcus multilocularis 3 oxoacyl acyl carrier protein reductase 0.0051 0.0439 0.0405
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0047 0.0385 0.0417
Echinococcus granulosus importin subunit beta 1 0.0057 0.0515 0.0572
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0042 0.0323 1
Trypanosoma brucei hypothetical protein, conserved 0.0107 0.1146 1
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0107 0.1146 0.1182
Entamoeba histolytica Ran family GTPase 0.0042 0.0323 0.7088
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0059 0.0539 0.0456
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0051 0.0439 0.0426
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0059 0.0539 0.06
Brugia malayi Pre-SET motif family protein 0.0059 0.0539 0.1074
Onchocerca volvulus 0.0107 0.1146 0.1948
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0059 0.0539 0.0505
Trichomonas vaginalis importin beta-1, putative 0.0047 0.0378 0.036
Mycobacterium tuberculosis Conserved protein 0.0107 0.1146 0.1182
Schistosoma mansoni 3-oxoacyl-[ACP] reductase 0.0051 0.0439 0.0482
Brugia malayi Calcitonin receptor-like protein seb-1 0.0149 0.1673 0.3336
Mycobacterium tuberculosis Possible 20-beta-hydroxysteroid dehydrogenase FabG3 (cortisone reductase) ((R)-20-hydroxysteroid dehydrogenase) 0.0051 0.0439 0.0426
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0572 0.0639
Mycobacterium leprae Probable lipase LipE 0.0107 0.1146 0.079
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0107 0.1146 0.1481
Plasmodium vivax ataxin-2 like protein, putative 0.0026 0.0116 0.0086
Trichomonas vaginalis esterase, putative 0.0107 0.1146 0.1182
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0051 0.0439 0.0426
Mycobacterium ulcerans lipase LipD 0.0107 0.1146 0.1182
Plasmodium vivax SET domain protein, putative 0.0059 0.0539 0.0538
Mycobacterium ulcerans short chain dehydrogenase 0.0051 0.0439 0.0426
Mycobacterium ulcerans short chain dehydrogenase 0.0051 0.0439 0.0426
Leishmania major importin beta-1 subunit, putative 0.0047 0.0378 0.3048
Schistosoma mansoni hypothetical protein 0.0047 0.0385 0.0417
Schistosoma mansoni terminal deoxycytidyl transferase 0.002 0.0041 0.0006
Brugia malayi hypothetical protein 0.0019 0.0035 0.0071
Loa Loa (eye worm) hypothetical protein 0.0059 0.0539 0.0671
Loa Loa (eye worm) hypothetical protein 0.0107 0.1146 0.1481
Loa Loa (eye worm) hypothetical protein 0.002 0.0041 0.0007
Loa Loa (eye worm) hypothetical protein 0.0107 0.1146 0.1481
Entamoeba histolytica hypothetical protein 0.0047 0.0378 0.8451
Loa Loa (eye worm) oxidoreductase 0.0051 0.0439 0.0539
Trypanosoma brucei beta-ketoacyl-ACP reductase 0.0051 0.0439 0.3607
Leishmania major pteridine reductase 1 0.0051 0.0439 0.3607
Echinococcus granulosus survival motor neuron protein 1 0.0233 0.2734 0.3217
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0051 0.0439 0.0426
Loa Loa (eye worm) latrophilin receptor protein 2 0.0047 0.0385 0.0466
Leishmania major dehydrogenase/oxidoreductase-like protein 0.0051 0.0439 0.3607
Echinococcus granulosus beta LACTamase domain containing family member 0.0107 0.1146 0.1324
Trypanosoma brucei importin beta-1 subunit, putative 0.0057 0.0515 0.429
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.002 0.0041 0.0006
Brugia malayi Pre-SET motif family protein 0.0413 0.5015 1
Trichomonas vaginalis set domain proteins, putative 0.047 0.5736 0.6092
Schistosoma mansoni lipoxygenase 0.0054 0.0478 0.0528
Trypanosoma cruzi beta-ketoacyl-ACP reductase 0.0051 0.0439 0.3607
Echinococcus granulosus GTP binding nuclear protein Ran 0.0042 0.0323 0.0343
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0685 0.8458 0.9003
Echinococcus multilocularis importin subunit beta 1 0.0057 0.0515 0.0481
Echinococcus multilocularis microtubule associated protein 2 0.0683 0.8426 0.842
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0116 0.0679
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0042 0.0323 0.0384
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0051 0.0439 0.0426
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0059 0.0539 0.06
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0051 0.0439 0.0426
Loa Loa (eye worm) hypothetical protein 0.0051 0.0439 0.0539
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0051 0.0439 0.0426
Trypanosoma brucei importin beta-1 subunit, putative 0.0057 0.0515 0.429
Loa Loa (eye worm) TAR-binding protein 0.0062 0.0572 0.0715
Echinococcus granulosus geminin 0.0166 0.1893 0.2214
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0059 0.0539 0.0505
Brugia malayi hypothetical protein 0.0019 0.0035 0.0071
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0051 0.0439 0.0426
Loa Loa (eye worm) hypothetical protein 0.0149 0.1673 0.2183
Mycobacterium tuberculosis Probable 3-oxoacyl-[acyl-carrier protein] reductase FabG2 (3-ketoacyl-acyl carrier protein reductase) 0.0051 0.0439 0.0426
Echinococcus granulosus microtubule associated protein 2 0.0683 0.8426 1
Plasmodium falciparum importin beta, putative 0.0057 0.0515 0.0513
Trypanosoma brucei pteridine reductase 1 0.0051 0.0439 0.3607
Echinococcus multilocularis snurportin 1 0.0612 0.7536 0.7527
Brugia malayi latrophilin 2 splice variant baaae 0.0102 0.1077 0.2148
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.023 0.27 0.3176
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0572 0.0639
Echinococcus granulosus histone lysine methyltransferase setb 0.0059 0.0539 0.06
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.023 0.27 0.3176
Toxoplasma gondii ABC1 family protein 0.0107 0.1146 0.1111
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0116 0.0679
Trypanosoma brucei oxidoreductase-like protein 0.0051 0.0439 0.3607
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0051 0.0439 0.0426
Schistosoma mansoni microtubule-associated protein tau 0.0683 0.8426 1
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0572 0.0639
Onchocerca volvulus 0.0051 0.0439 0.0709
Mycobacterium tuberculosis Probable oxidoreductase 0.0051 0.0439 0.0426
Schistosoma mansoni dihydropteridine reductase 0.0051 0.0439 0.0482
Mycobacterium ulcerans short chain dehydrogenase 0.0051 0.0439 0.0426
Plasmodium vivax hypothetical protein, conserved 0.0107 0.1146 0.1187
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.0234 0.0236
Schistosoma mansoni DNA polymerase eta 0.002 0.0041 0.0006
Trypanosoma cruzi beta-ketoacyl-ACP reductase 0.0051 0.0439 0.3607
Mycobacterium ulcerans oxidoreductase 0.0051 0.0439 0.0426
Schistosoma mansoni hypothetical protein 0.0047 0.0385 0.0417
Mycobacterium tuberculosis Probable hydrolase 0.0107 0.1146 0.1182
Schistosoma mansoni hypothetical protein 0.0035 0.0234 0.0236
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0572 0.0639
Mycobacterium ulcerans 3-alpha-hydroxysteroid dehydrogenase 0.0051 0.0439 0.0426
Entamoeba histolytica hypothetical protein 0.0035 0.0234 0.4839
Mycobacterium ulcerans short chain dehydrogenase 0.0051 0.0439 0.0426
Mycobacterium ulcerans beta-lactamase 0.0107 0.1146 0.1182
Trichomonas vaginalis D-aminoacylase, putative 0.0107 0.1146 0.1182
Echinococcus granulosus tar DNA binding protein 0.0062 0.0572 0.0639
Leishmania major 3-oxoacyl-ACP reductase, putative 0.0051 0.0439 0.3607
Mycobacterium ulcerans short chain dehydrogenase 0.0051 0.0439 0.0426
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.023 0.27 0.3553
Loa Loa (eye worm) hypothetical protein 0.0107 0.1146 0.1481
Onchocerca volvulus 0.0059 0.0539 0.0883
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0051 0.0439 0.0426
Brugia malayi RNA binding protein 0.0062 0.0572 0.114
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0042 0.0323 0.0289
Brugia malayi TAR-binding protein 0.0062 0.0572 0.114
Echinococcus multilocularis dna polymerase kappa 0.002 0.0041 0.0005
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0107 0.1146 0.2285
Leishmania major oxidoreductase-like protein 0.0051 0.0439 0.3607
Onchocerca volvulus 0.0047 0.039 0.0622
Toxoplasma gondii 2,4-dienoyl CoA reductase 2, peroxisomal family protein 0.0051 0.0439 0.0349
Schistosoma mansoni survival motor neuron protein 0.0047 0.039 0.0423
Mycobacterium tuberculosis Probable esterase LipL 0.0107 0.1146 0.1182
Schistosoma mansoni hypothetical protein 0.0047 0.0385 0.0417
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0051 0.0439 0.0539
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0107 0.1146 0.1182
Plasmodium falciparum 3-oxoacyl-[acyl-carrier-protein] reductase 0.0051 0.0439 0.0432
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0051 0.0439 0.0426
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0051 0.0439 0.0876
Echinococcus multilocularis dna polymerase eta 0.002 0.0041 0.0005
Loa Loa (eye worm) transcription factor SMAD2 0.0119 0.1299 0.1685
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0047 0.0378 0.036
Plasmodium vivax 3-oxoacyl-[acyl-carrier-protein] reductase, putative 0.0051 0.0439 0.0432
Onchocerca volvulus 0.047 0.5736 1
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0107 0.1146 0.1324
Brugia malayi RNA, U transporter 1 0.0163 0.1853 0.3695
Mycobacterium tuberculosis Probable lipase LipD 0.0107 0.1146 0.1182
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0413 0.5015 0.6638
Mycobacterium ulcerans short chain dehydrogenase 0.0051 0.0439 0.0426
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0149 0.1673 0.2183
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0047 0.0385 0.0417
Brugia malayi Doublecortin family protein 0.0019 0.0035 0.0071
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0107 0.1146 0.1324
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0042 0.0323 0.0645
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0051 0.0439 0.0426
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0042 0.0323 0.0308
Plasmodium vivax enoyl-acyl carrier protein reductase 0.0759 0.939 1
Trichomonas vaginalis penicillin-binding protein, putative 0.0107 0.1146 0.1182
Trichomonas vaginalis penicillin-binding protein, putative 0.0107 0.1146 0.1182
Trichomonas vaginalis D-aminoacylase, putative 0.0107 0.1146 0.1182
Toxoplasma gondii HEAT repeat-containing protein 0.0057 0.0515 0.043
Brugia malayi hypothetical protein 0.0035 0.0234 0.0466
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0047 0.039 0.0778
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.023 0.27 0.2674
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0116 0.0086
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0572 0.0639
Onchocerca volvulus 0.0051 0.0439 0.0709
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.023 0.27 0.3176
Schistosoma mansoni hypothetical protein 0.0047 0.0385 0.0417
Schistosoma mansoni hypothetical protein 0.0102 0.1077 0.1241
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0051 0.0439 0.0426
Schistosoma mansoni ran 0.0042 0.0323 0.0343
Mycobacterium ulcerans enoyl-(acyl carrier protein) reductase 0.0759 0.939 1
Brugia malayi MH2 domain containing protein 0.0119 0.1299 0.2591
Echinococcus multilocularis geminin 0.0166 0.1893 0.1864
Trypanosoma cruzi hypothetical protein, conserved 0.0107 0.1146 1
Wolbachia endosymbiont of Brugia malayi enoyl-ACP reductase 0.0759 0.939 1
Brugia malayi hypothetical protein 0.0233 0.2734 0.5453
Schistosoma mansoni hypothetical protein 0.0166 0.1893 0.2214
Loa Loa (eye worm) MH2 domain-containing protein 0.0119 0.1299 0.1685
Mycobacterium ulcerans short chain dehydrogenase 0.0051 0.0439 0.0426
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.023 0.27 0.3176
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0047 0.0385 0.0351
Brugia malayi ImpB/MucB/SamB family protein 0.002 0.0041 0.0081
Trichomonas vaginalis hypothetical protein 0.0759 0.939 1
Entamoeba histolytica hypothetical protein 0.0035 0.0234 0.4839
Chlamydia trachomatis enoyl-acyl-carrier protein reductase 0.0759 0.939 1
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.002 0.0041 0.0007
Mycobacterium leprae NADH-DEPENDENT ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE INHA (NADH-DEPENDENT ENOYL-ACP REDUCTASE) 0.0759 0.939 1
Loa Loa (eye worm) beta-lactamase 0.0107 0.1146 0.1481
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0051 0.0439 0.0426
Echinococcus granulosus snurportin 1 0.0612 0.7536 0.894
Brugia malayi Importin beta-1 subunit 0.0057 0.0515 0.1027
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0042 0.0323 0.2557
Echinococcus multilocularis tar DNA binding protein 0.0062 0.0572 0.0538
Toxoplasma gondii enoyl-acyl carrier reductase ENR 0.0759 0.939 1
Entamoeba histolytica hypothetical protein 0.0035 0.0234 0.4839
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.0234 0.0199
Brugia malayi hypothetical protein 0.0026 0.0116 0.0231
Mycobacterium ulcerans short chain dehydrogenase 0.0051 0.0439 0.0426
Leishmania major dehydrogenase/oxidoreductase-like protein 0.0051 0.0439 0.3607
Schistosoma mansoni ran 0.0042 0.0323 0.0343
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0059 0.0539 0.06
Mycobacterium ulcerans short chain dehydrogenase 0.0051 0.0439 0.0426
Loa Loa (eye worm) hypothetical protein 0.0057 0.0515 0.0639
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0047 0.0378 0.036
Brugia malayi ImpB/MucB/SamB family protein 0.002 0.0041 0.0081
Echinococcus granulosus dna polymerase kappa 0.002 0.0041 0.0006
Loa Loa (eye worm) hypothetical protein 0.0026 0.0116 0.0107
Mycobacterium tuberculosis Probable lipase LipE 0.0107 0.1146 0.1182
Mycobacterium ulcerans esterase/lipase LipP 0.0107 0.1146 0.1182
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0051 0.0439 0.0426
Mycobacterium ulcerans 3-oxoacyl-ACP reductase 0.0051 0.0439 0.0426
Leishmania major GTP-binding protein, putative 0.0042 0.0323 0.2557
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0116 0.0086
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.023 0.27 0.2674
Loa Loa (eye worm) RNA binding protein 0.0062 0.0572 0.0715
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0059 0.0539 0.06
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0051 0.0439 0.0426
Mycobacterium tuberculosis Conserved protein 0.0107 0.1146 0.1182
Mycobacterium leprae conserved hypothetical protein 0.0107 0.1146 0.079
Schistosoma mansoni hypothetical protein 0.0047 0.039 0.0423
Onchocerca volvulus 0.0107 0.1146 0.1948
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.023 0.27 0.5385
Mycobacterium ulcerans short chain dehydrogenase 0.0051 0.0439 0.0426
Mycobacterium ulcerans 3-oxoacyl-ACP reductase 0.0051 0.0439 0.0426
Mycobacterium tuberculosis Conserved protein 0.0107 0.1146 0.1182
Loa Loa (eye worm) hypothetical protein 0.0102 0.1077 0.1389
Trichomonas vaginalis ran, putative 0.0042 0.0323 0.0302
Plasmodium vivax importin-beta 2, putative 0.0057 0.0515 0.0513
Echinococcus multilocularis GPCR, family 2 0.0047 0.0385 0.0351
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0107 0.1146 0.1182
Entamoeba histolytica hypothetical protein 0.0035 0.0234 0.4839
Loa Loa (eye worm) hypothetical protein 0.0107 0.1146 0.1481
Loa Loa (eye worm) hypothetical protein 0.0107 0.1146 0.1481
Trypanosoma brucei PAB1-binding protein , putative 0.0026 0.0116 0.0679
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0042 0.0323 0.0308
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0051 0.0439 0.0426
Mycobacterium ulcerans 20-beta-hydroxysteroid dehydrogenase FabG3 0.0051 0.0439 0.0426
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0047 0.0385 0.0351
Toxoplasma gondii short chain dehydrogenase family protein, putative 0.0051 0.0439 0.0349
Trypanosoma cruzi hypothetical protein, conserved 0.0107 0.1146 1
Schistosoma mansoni hypothetical protein 0.0166 0.1893 0.2214
Brugia malayi beta-lactamase 0.0107 0.1146 0.2285
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.0234 0.0236
Mycobacterium tuberculosis Possible oxidoreductase 0.0051 0.0439 0.0426
Loa Loa (eye worm) retinol dehydrogenase 12 0.0051 0.0439 0.0539
Leishmania major hypothetical protein, conserved 0.0107 0.1146 1
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0057 0.0511 0.0567
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0051 0.0439 0.0876
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0051 0.0439 0.3607
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0054 0.0478 0.0528
Schistosoma mansoni hypothetical protein 0.0612 0.7536 0.894
Echinococcus granulosus GPCR family 2 0.0047 0.0385 0.0417
Brugia malayi beta-lactamase family protein 0.0107 0.1146 0.2285
Echinococcus granulosus 3 oxoacyl acyl carrier protein reductase 0.0051 0.0439 0.0482
Trypanosoma cruzi importin beta-1 subunit, putative 0.0047 0.0378 0.3048
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0612 0.7536 1
Entamoeba histolytica 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0051 0.0439 1
Loa Loa (eye worm) hypothetical protein 0.0047 0.0385 0.0466
Plasmodium falciparum enoyl-acyl carrier reductase 0.0759 0.939 1
Mycobacterium ulcerans hypothetical protein 0.0107 0.1146 0.1182
Trichomonas vaginalis D-aminoacylase, putative 0.0107 0.1146 0.1182
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0042 0.0323 0.2557
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0042 0.0323 0.0224
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.023 0.27 0.3176
Mycobacterium ulcerans short chain dehydrogenase 0.0051 0.0439 0.0426
Echinococcus granulosus dna polymerase eta 0.002 0.0041 0.0006
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0062 0.0572 0.0715
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.002 0.0041 0.0006
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0149 0.1673 0.3336
Brugia malayi RNA recognition motif domain containing protein 0.0062 0.0572 0.114
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0107 0.1146 0.1182
Brugia malayi beta-lactamase family protein 0.0107 0.1146 0.2285
Toxoplasma gondii 3-ketoacyl-(acyl-carrier-protein) reductase 0.0051 0.0439 0.0349

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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