TDR Targets

Basic information

Technical information

TDR Targets ID: 511842
Name: 2-(2-methylpropyl)-1-[[4-[2-(2H-tetrazol-5-yl )phenyl]phenyl]methyl]pyrazolo[3,4-b]pyridin- 3-one
MW: 425.486 | Formula: C24H23N7O
H donors: 1 H acceptors: 5 LogP: 4.4 Rotable bonds: 6
Rule of 5 violations (Lipinski): 1
SMILES: CC(Cn1c(=O)c2c(n1Cc1ccc(cc1)c1ccccc1c1n[nH]nn1)nccc2)C
InChi: 1S/C24H23N7O/c1-16(2)14-31-24(32)21-8-5-13-25-23(21)30(31)15-17-9-11-18(12-10-17)19-6-3-4-7-20(19)22-26-28-29-27-22/h3-13,16H,14-15H2,1-2H3,(H,26,27,28,29)
InChiKey: JKWVJTQZCHOGJJ-UHFFFAOYSA-N

Network

Hover on a compound node to display the structore

Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

This is a work in progress. Come back soon to try this features!

Clustering layers

This is a work in progress. Come back soon to try this features!

Synonyms

2-isobutyl-1-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]pyrazolo[3,4-b]pyridin-3-one
2-isobutyl-1-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]-3-pyrazolo[3,4-b]pyridinone
2-(2-methylpropyl)-1-[[4-[2-(2H-1,2,3,4-tetrazol-5-yl)phenyl]phenyl]methyl]pyrazolo[3,4-b]pyridin-3-one
2-isobutyl-1-[4-[2-(2H-tetrazol-5-yl)phenyl]benzyl]pyrazolo[3,4-b]pyridin-3-one

Targets

Known targets for this compound

Species	Target name	Source	Bibliographic reference
Rattus norvegicus	Type-1A angiotensin II receptor	Starlite/ChEMBL	References

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

Species	Potential target	Known druggable target	Length	Alignment span	Identity
Loa Loa (eye worm)	hypothetical protein	Type-1A angiotensin II receptor	359 aa	330 aa	26.7 %
Echinococcus granulosus	allatostatin A receptor	Type-1A angiotensin II receptor	359 aa	348 aa	25.9 %
Echinococcus multilocularis	neuropeptide receptor	Type-1A angiotensin II receptor	359 aa	316 aa	25.3 %
Schistosoma japonicum	ko:K04209 neuropeptide Y receptor, invertebrate, putative	Type-1A angiotensin II receptor	359 aa	311 aa	23.5 %
Onchocerca volvulus		Type-1A angiotensin II receptor	359 aa	395 aa	23.0 %
Echinococcus granulosus	growth hormone secretagogue receptor type 1	Type-1A angiotensin II receptor	359 aa	351 aa	21.9 %
Onchocerca volvulus		Type-1A angiotensin II receptor	359 aa	294 aa	23.8 %
Brugia malayi	putative neuropeptide receptor NPR1	Type-1A angiotensin II receptor	359 aa	295 aa	27.5 %
Schistosoma mansoni	opsin-like receptor	Type-1A angiotensin II receptor	359 aa	299 aa	25.1 %
Onchocerca volvulus		Type-1A angiotensin II receptor	359 aa	386 aa	24.9 %
Echinococcus multilocularis	pyroglutamylated rfamide peptide receptor	Type-1A angiotensin II receptor	359 aa	406 aa	20.0 %
Schistosoma mansoni	adenoreceptor	Type-1A angiotensin II receptor	359 aa	329 aa	24.0 %
Echinococcus granulosus	neuropeptide receptor	Type-1A angiotensin II receptor	359 aa	316 aa	25.0 %
Schistosoma mansoni	peptide (allatostatin)-like receptor	Type-1A angiotensin II receptor	359 aa	314 aa	26.1 %
Echinococcus multilocularis	G-protein coupled receptor, putative	Type-1A angiotensin II receptor	359 aa	308 aa	22.4 %
Brugia malayi	GnHR receptor homolog	Type-1A angiotensin II receptor	359 aa	364 aa	20.9 %
Brugia malayi	ORL1-like opioid receptor	Type-1A angiotensin II receptor	359 aa	314 aa	20.1 %
Schistosoma japonicum	Rhodopsin, putative	Type-1A angiotensin II receptor	359 aa	327 aa	24.2 %
Echinococcus granulosus	tm gpcr rhodopsin	Type-1A angiotensin II receptor	359 aa	303 aa	22.4 %
Echinococcus multilocularis	allatostatin A receptor	Type-1A angiotensin II receptor	359 aa	348 aa	25.9 %
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	Type-1A angiotensin II receptor	359 aa	303 aa	22.4 %
Schistosoma japonicum	ko:K04134 cholinergic receptor, invertebrate, putative	Type-1A angiotensin II receptor	359 aa	336 aa	22.3 %
Onchocerca volvulus		Type-1A angiotensin II receptor	359 aa	303 aa	25.1 %
Echinococcus multilocularis	growth hormone secretagogue receptor type 1	Type-1A angiotensin II receptor	359 aa	351 aa	21.9 %
Loa Loa (eye worm)	neuropeptide F receptor	Type-1A angiotensin II receptor	359 aa	356 aa	24.2 %
Echinococcus granulosus	thyrotropin releasing hormone receptor	Type-1A angiotensin II receptor	359 aa	337 aa	24.0 %
Onchocerca volvulus	E3 ubiquitin-protein ligase rpm-1 homolog	Type-1A angiotensin II receptor	359 aa	352 aa	20.5 %
Onchocerca volvulus		Type-1A angiotensin II receptor	359 aa	312 aa	19.2 %
Echinococcus multilocularis	thyrotropin releasing hormone receptor	Type-1A angiotensin II receptor	359 aa	334 aa	23.7 %
Echinococcus granulosus	pyroglutamylated rfamide peptide receptor	Type-1A angiotensin II receptor	359 aa	407 aa	19.4 %
Onchocerca volvulus		Type-1A angiotensin II receptor	359 aa	314 aa	25.8 %
Schistosoma mansoni	peptide (FMRFamide/somatostatin)-like receptor	Type-1A angiotensin II receptor	359 aa	346 aa	18.2 %
Loa Loa (eye worm)	hypothetical protein	Type-1A angiotensin II receptor	359 aa	335 aa	23.3 %

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Trypanosoma cruzi	carnitine/choline acetyltransferase, putative	0.0049	0.1024	0.1684
Loa Loa (eye worm)	cytochrome P450 family protein	0.0021	0.0135	0.0143
Echinococcus multilocularis	carnitine O palmitoyltransferase 2	0.0049	0.1024	0.1024
Loa Loa (eye worm)	animal heme peroxidase	0.0029	0.0388	0.0509
Trypanosoma brucei	N-myristoyltransferase	0.0189	0.5417	1
Loa Loa (eye worm)	hypothetical protein	0.0029	0.0388	0.0509
Trypanosoma brucei	tyrosyl-DNA Phosphodiesterase (Tdp1), putative	0.0071	0.1709	0.2981
Brugia malayi	Choline/Carnitine o-acyltransferase family protein	0.0161	0.4547	0.6503
Onchocerca volvulus	Dual oxidase homolog	0.0029	0.0388	0.0509
Loa Loa (eye worm)	hypothetical protein	0.0047	0.0968	0.1344
Trichomonas vaginalis	N-myristoyl transferase, putative	0.0124	0.3381	0.5938
Echinococcus granulosus	FTZ F1 alpha	0.0018	0.0035	0.0035
Loa Loa (eye worm)	animal heme peroxidase	0.0029	0.0388	0.0509
Brugia malayi	Animal haem peroxidase family protein	0.0029	0.0388	0.0509
Leishmania major	carnitine/choline acetyltransferase, putative	0.0049	0.1024	0.1684
Loa Loa (eye worm)	hypothetical protein	0.0029	0.0388	0.0509
Loa Loa (eye worm)	hypothetical protein	0.0029	0.0388	0.0509
Trypanosoma brucei	carnitine O-palmitoyltransferase II, putative	0.0049	0.1024	0.1684
Schistosoma mansoni	CREB-binding protein 2	0.0101	0.2648	0.4855
Loa Loa (eye worm)	hypothetical protein	0.0049	0.1033	0.1437
Brugia malayi	hypothetical protein	0.0029	0.0388	0.0509
Echinococcus multilocularis	FTZ F1 nuclear receptor protein	0.0018	0.0035	0.0035
Echinococcus granulosus	hepatocyte nuclear factor 4 alpha	0.0018	0.0035	0.0035
Echinococcus granulosus	transcription factor Dp 1	0.0041	0.0771	0.0771
Onchocerca volvulus	Peroxidase homolog	0.0029	0.0388	0.0509
Onchocerca volvulus		0.0049	0.1024	0.1425
Entamoeba histolytica	glycylpeptide N-tetradecanoyltransferase, putative	0.0189	0.5417	1
Trichomonas vaginalis	r2r3-MYB transcription factor, putative	0.003	0.041	0.0009
Trichomonas vaginalis	MYB, putative	0.003	0.041	0.0009
Leishmania major	N-myristoyl transferase, putative	0.0189	0.5417	1
Loa Loa (eye worm)	CYP4Cod1	0.0021	0.0135	0.0143
Loa Loa (eye worm)	CBP-B	0.007	0.168	0.2371
Onchocerca volvulus		0.0029	0.0388	0.0509
Loa Loa (eye worm)	hypothetical protein	0.0029	0.0388	0.0509
Onchocerca volvulus		0.0049	0.1024	0.1425
Trypanosoma cruzi	choline/carnitine O-acyltransferase, putative	0.0161	0.4547	0.8353
Echinococcus multilocularis	nuclear receptor 2DBD gamma	0.0018	0.0035	0.0035
Schistosoma mansoni	tyrosyl-DNA phosphodiesterase	0.0071	0.1709	0.311
Echinococcus granulosus	CREB binding protein	0.0062	0.1434	0.1434
Loa Loa (eye worm)	carnitine O-palmitoyltransferase I isoform	0.0049	0.1024	0.1425
Brugia malayi	Calcitonin receptor-like protein seb-1	0.0049	0.1033	0.1437
Onchocerca volvulus		0.0029	0.0388	0.0509
Schistosoma mansoni	peroxidasin	0.0029	0.0388	0.0656
Trypanosoma cruzi	N-myristoyl transferase, putative	0.0189	0.5417	1
Schistosoma mansoni	hypothetical protein	0.0034	0.0542	0.094
Schistosoma mansoni	CREB-binding protein 1 (SmCBP1)	0.0101	0.2648	0.4855
Onchocerca volvulus	Peroxidase homolog	0.0029	0.0388	0.0509
Brugia malayi	Animal haem peroxidase family protein	0.0029	0.0388	0.0509
Echinococcus granulosus	nuclear receptor 2DBD gamma	0.0018	0.0035	0.0035
Onchocerca volvulus	Peroxidasin homolog	0.0029	0.0388	0.0509
Brugia malayi	Animal haem peroxidase family protein	0.0029	0.0388	0.0509
Brugia malayi	N-myristoyltransferase 2	0.0189	0.5417	0.7757
Brugia malayi	TAZ zinc finger family protein	0.0101	0.2648	0.3766
Brugia malayi	Cytochrome P450 family protein	0.0021	0.0135	0.0143
Onchocerca volvulus		0.0029	0.0388	0.0509
Echinococcus granulosus	peroxidasin	0.0029	0.0388	0.0388
Echinococcus granulosus	Nuclear hormone receptor family member nhr 41	0.0018	0.0035	0.0035
Loa Loa (eye worm)	hypothetical protein	0.0161	0.4547	0.6503
Schistosoma mansoni	cellular tumor antigen P53	0.0049	0.102	0.183
Loa Loa (eye worm)	cytochrome P450 family protein	0.0021	0.0135	0.0143
Echinococcus granulosus	COUP TF:Svp nuclear hormone receptor	0.0018	0.0035	0.0035
Onchocerca volvulus		0.0049	0.1024	0.1425
Echinococcus multilocularis	CREB binding protein	0.0069	0.1653	0.1653
Brugia malayi	Cytochrome P450 family protein	0.0021	0.0135	0.0143
Onchocerca volvulus	Chorion peroxidase homolog	0.0029	0.0388	0.0509
Loa Loa (eye worm)	pigment dispersing factor receptor c	0.0049	0.1033	0.1437
Trypanosoma cruzi	hypothetical protein, conserved	0.0049	0.1024	0.1684
Mycobacterium ulcerans	cytochrome P450 185A4 Cyp185A4	0.0021	0.0135	0.5
Loa Loa (eye worm)	hypothetical protein	0.0029	0.0388	0.0509
Leishmania major	choline/Carnitine o-acyltransferase-like protein	0.0161	0.4547	0.8353
Brugia malayi	Peroxidasin	0.0029	0.0388	0.0509
Loa Loa (eye worm)	cytochrome P450 family protein	0.0032	0.0483	0.0646
Echinococcus granulosus	choline O acetyltransferase	0.0185	0.531	0.531
Loa Loa (eye worm)	hypothetical protein	0.0034	0.0542	0.073
Trichomonas vaginalis	N-myristoyl transferase, putative	0.0189	0.5417	1
Echinococcus multilocularis	transcription factor Dp 1	0.0041	0.0771	0.0771
Plasmodium vivax	glycylpeptide N-tetradecanoyltransferase, putative	0.0189	0.5417	0.5
Brugia malayi	Choline/Carnitine o-acyltransferase family protein	0.0049	0.1024	0.1425
Onchocerca volvulus		0.0049	0.1024	0.1425
Trypanosoma cruzi	carnitine O-palmitoyltransferase II, putative	0.0049	0.1024	0.1684
Trypanosoma brucei	carnitine O-acetyltransferase, putative	0.0049	0.1024	0.1684
Loa Loa (eye worm)	pax transcription factor protein 2	0.0238	0.6973	1
Onchocerca volvulus		0.0238	0.6973	1
Echinococcus multilocularis	glycylpeptide N tetradecanoyltransferase	0.0189	0.5417	0.5417
Loa Loa (eye worm)	hypothetical protein	0.0029	0.0388	0.0509
Echinococcus multilocularis	hepatocyte nuclear factor 4 alpha	0.0018	0.0035	0.0035
Trypanosoma cruzi	N-myristoyl transferase, putative	0.0189	0.5417	1
Trichomonas vaginalis	r2r3-MYB transcription factor, putative	0.003	0.041	0.0009
Loa Loa (eye worm)	animal heme peroxidase	0.0029	0.0388	0.0509
Loa Loa (eye worm)	hypothetical protein	0.0029	0.0388	0.0509
Echinococcus granulosus	ecdysone induced protein 78C	0.0018	0.0035	0.0035
Plasmodium falciparum	glycylpeptide N-tetradecanoyltransferase	0.0189	0.5417	0.5
Echinococcus granulosus	carnitine O palmitoyltransferase 2	0.0049	0.1024	0.1024
Schistosoma mansoni	N-myristoyltransferase	0.0189	0.5417	1
Onchocerca volvulus		0.015	0.4185	0.5981
Loa Loa (eye worm)	tyrosyl-DNA phosphodiesterase	0.0071	0.1709	0.2413
Trypanosoma cruzi	choline/carnitine O-acetyltransferase, putative	0.0049	0.1024	0.1684
Toxoplasma gondii	Myb family DNA-binding domain-containing protein	0.003	0.0409	0.5
Schistosoma mansoni	choline o-acyltransferase	0.0049	0.1024	0.1837
Trypanosoma cruzi	choline/carnitine O-acyltransferase, putative	0.0161	0.4547	0.8353
Trypanosoma cruzi	hypothetical protein, conserved	0.0049	0.1024	0.1684
Echinococcus granulosus	FTZ F1 nuclear receptor protein	0.0018	0.0035	0.0035
Brugia malayi	Tyrosyl-DNA phosphodiesterase family protein	0.0071	0.1709	0.2413
Brugia malayi	hypothetical protein	0.015	0.4185	0.5981
Trypanosoma cruzi	choline/carnitine O-acyltransferase, putative	0.0049	0.1024	0.1684
Loa Loa (eye worm)	hypothetical protein	0.0185	0.531	0.7603
Brugia malayi	Pax transcription factor protein 2	0.0238	0.6973	1
Echinococcus multilocularis	choline O acetyltransferase	0.0185	0.531	0.531
Echinococcus multilocularis	nuclear receptor 2DBD gamma	0.0018	0.0035	0.0035
Brugia malayi	Choline/Carnitine o-acyltransferase family protein	0.0049	0.1024	0.1425
Loa Loa (eye worm)	hypothetical protein	0.0029	0.0388	0.0509
Onchocerca volvulus		0.0049	0.102	0.142
Leishmania major	tyrosyl-DNA phosphodiesterase 1	0.0071	0.1709	0.2981
Echinococcus granulosus	glycylpeptide N tetradecanoyltransferase	0.0189	0.5417	0.5417
Echinococcus multilocularis	carnitine O palmitoyltransferase 1, liver	0.0161	0.4547	0.4547
Loa Loa (eye worm)	hypothetical protein	0.0029	0.0388	0.0509
Trypanosoma brucei	N-myristoyl transferase, putative	0.0189	0.5417	1
Echinococcus multilocularis	COUP TF:Svp nuclear hormone receptor	0.0018	0.0035	0.0035
Brugia malayi	Choline O-acetyltransferase	0.0185	0.531	0.7603
Echinococcus granulosus	nuclear receptor 2DBD gamma	0.0018	0.0035	0.0035
Echinococcus multilocularis	Nuclear hormone receptor family member nhr 41	0.0018	0.0035	0.0035
Trypanosoma cruzi	tyrosyl-DNA Phosphodiesterase (Tdp1), putative	0.0071	0.1709	0.2981
Brugia malayi	latrophilin 2 splice variant baaae	0.0034	0.0542	0.073
Brugia malayi	Animal haem peroxidase family protein	0.0029	0.0388	0.0509
Brugia malayi	Blistered cuticle protein 3	0.0029	0.0388	0.0509
Giardia lamblia	CDC72	0.0189	0.5417	1
Schistosoma mansoni	peroxidasin	0.0029	0.0388	0.0656
Loa Loa (eye worm)	animal heme peroxidase	0.0029	0.0388	0.0509
Loa Loa (eye worm)	blistered cuticle protein 3	0.0029	0.0388	0.0509
Echinococcus granulosus	retinoic acid receptor rxr beta a	0.0018	0.0035	0.0035
Trypanosoma brucei	carnitine O-palmitoyltransferase, putative	0.0049	0.1024	0.1684
Loa Loa (eye worm)	hypothetical protein	0.0029	0.0388	0.0509
Loa Loa (eye worm)	hypothetical protein	0.0049	0.102	0.142
Trypanosoma cruzi	hypothetical protein, conserved	0.0049	0.1024	0.1684
Trypanosoma cruzi	carnitine O-acetyltransferase, putative	0.0049	0.1024	0.1684
Trypanosoma cruzi	carnitine/choline acetyltransferase, putative	0.0049	0.1024	0.1684
Loa Loa (eye worm)	N-myristoyltransferase 2	0.0189	0.5417	0.7757
Echinococcus multilocularis	ecdysone induced protein 78C	0.0018	0.0035	0.0035
Trypanosoma cruzi	tyrosyl-DNA Phosphodiesterase (Tdp1), putative	0.0071	0.1709	0.2981
Loa Loa (eye worm)	choline O-acetyltransferase	0.0185	0.531	0.7603
Echinococcus granulosus	tyrosyl DNA phosphodiesterase 1	0.0071	0.1709	0.1709
Leishmania major	carnitine palmitoyltransferase-like protein	0.0049	0.1024	0.1684
Echinococcus multilocularis	tumor protein p63	0.0334	1	1
Echinococcus multilocularis	thyroid hormone receptor alpha	0.0018	0.0035	0.0035
Trypanosoma cruzi	hypothetical protein, conserved	0.0049	0.1024	0.1684
Brugia malayi	Choline O-acetyltransferase	0.0185	0.531	0.7603
Schistosoma mansoni	choline o-acyltransferase	0.0185	0.531	0.9801
Echinococcus multilocularis	tyrosyl DNA phosphodiesterase 1	0.0071	0.1709	0.1709
Loa Loa (eye worm)	hypothetical protein	0.0029	0.0388	0.0509
Trypanosoma brucei	carnitine O-palmitoyltransferase II, putative	0.0049	0.1024	0.1684
Echinococcus granulosus	CREB binding protein	0.0101	0.2648	0.2648
Loa Loa (eye worm)	hypothetical protein	0.0029	0.0388	0.0509
Brugia malayi	Corticotropin releasing factor receptor 2 precursor, putative	0.0049	0.1033	0.1437
Echinococcus multilocularis	peroxidasin	0.0029	0.0388	0.0388
Echinococcus granulosus	carnitine O palmitoyltransferase 1 liver	0.0161	0.4547	0.4547
Entamoeba histolytica	tyrosyl-DNA phosphodiesterase, putative	0.0071	0.1709	0.2602
Trypanosoma brucei	hypothetical protein, conserved	0.0049	0.1024	0.1684
Brugia malayi	Cytochrome P450 family protein	0.0032	0.0483	0.0646
Echinococcus multilocularis	FTZ F1 alpha	0.0018	0.0035	0.0035
Loa Loa (eye worm)	hypothetical protein	0.0029	0.0388	0.0509
Loa Loa (eye worm)	choline/Carnitine O-acyltransferase	0.0049	0.1024	0.1425
Trypanosoma cruzi	hypothetical protein, conserved	0.0049	0.1024	0.1684
Loa Loa (eye worm)	hypothetical protein	0.0029	0.0388	0.0509
Brugia malayi	Animal haem peroxidase family protein	0.0029	0.0388	0.0509
Onchocerca volvulus	Peroxidasin homolog	0.0029	0.0388	0.0509
Loa Loa (eye worm)	hypothetical protein	0.015	0.4185	0.5981

Activities

Activity type	Activity value	Assay description	Source	Reference
IC50 (binding)	= 2300 nM	Displacement of [125I]Sar1,Ile8-Ang2 from AT1 receptor in Wistar rat hepatic membrane	ChEMBL.	18318468
IC50 (binding)	= 2300 nM	Displacement of [125I]Sar1,Ile8-Ang2 from AT1 receptor in Wistar rat hepatic membrane	ChEMBL.	18318468

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

PubChem: 24827769

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.

Detailed information for compound 511842