Detailed information for compound 540016

Basic information

Technical information
  • TDR Targets ID: 540016
  • Name: [(2R,3R,4R,5S)-4,5-di(butanoyloxy)-2-(butanoy loxymethyl)-1-butyl-3-piperidyl] butanoate
  • MW: 499.637 | Formula: C26H45NO8
  • H donors: 0 H acceptors: 4 LogP: 4.42 Rotable bonds: 20
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCCN1C[C@H](OC(=O)CCC)[C@H]([C@@H]([C@H]1COC(=O)CCC)OC(=O)CCC)OC(=O)CCC
  • InChi: 1S/C26H45NO8/c1-6-11-16-27-17-20(33-22(29)13-8-3)26(35-24(31)15-10-5)25(34-23(30)14-9-4)19(27)18-32-21(28)12-7-2/h19-20,25-26H,6-18H2,1-5H3/t19-,20+,25-,26-/m1/s1
  • InChiKey: MKGDNVHZSCXBKR-KYVQNOJUSA-N  


Substructure search Similarity search

Network

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Synonyms

  • butanoic acid [(2R,3R,4R,5S)-1-butyl-4,5-bis(1-oxobutoxy)-2-(1-oxobutoxymethyl)-3-piperidinyl] ester
  • [(2R,3R,4R,5S)-4,5-di(butanoyloxy)-2-(butanoyloxymethyl)-1-butyl-piperidin-3-yl] butanoate
  • butyric acid [(2R,3R,4R,5S)-1-butyl-4,5-dibutyryloxy-2-(butyryloxymethyl)-3-piperidyl] ester
  • [(2R,3R,4R,5S)-4,5-di(butanoyloxy)-2-(butanoyloxymethyl)-1-butylpiperidin-3-yl] butanoate
  • glycovir
  • 131262-82-3
  • 1,5-(BUTYLIMINO)-1,5-DIDEOXY-D-GLUCITOL, TETRABUTANOATE
  • Butanoic acid, 1-butyl-2-((1-oxobutoxy)methyl)-3,4,5-piperidinetriyl ester, (2R-(2alpha,3beta,4alpha,5beta))-
  • DRG-0193
  • NSC 670880
  • Perbutylated-N-butyl-1-deoxynojiromycin
  • SC 49483
  • 1-Butyl-2R,2.alpha.-[(1-oxybutoxy)methyl]-3.beta.,4.alpha.,5.beta.-piperidinetriyl butanoate

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus Protein patched homolog 1 0.0042 0.0686 0.0855
Plasmodium falciparum calcium-dependent protein kinase 5 0.0033 0.048 0.0414
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0172 0.3646 0.3602
Schistosoma mansoni sugar transporter 0.0015 0.0069 0.0027
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0069 0.0016
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0033 0.0479 0.0573
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0392 0.0659
Schistosoma mansoni glucose transport protein 0.0106 0.2146 0.6801
Entamoeba histolytica hypothetical protein 0.009 0.1779 0.893
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.038 0.0437
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0069 0.0016
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0527 0.0926
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0032 0.0454 0.0538
Loa Loa (eye worm) hypothetical protein 0.0015 0.0069 0.0079
Brugia malayi MH1 domain containing protein 0.0017 0.0111 0.0208
Schistosoma mansoni hypothetical protein 0.0063 0.1169 0.3616
Echinococcus granulosus lamin 0.003 0.0421 0.0493
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0043 0.0718 0.3825
Trichomonas vaginalis PIKK family atypical protein kinase 0.0023 0.0262 0.04
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.0718 0.1305
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0464 0.0802
Loa Loa (eye worm) sugar transporter 0.0015 0.0069 0.0079
Mycobacterium tuberculosis Probable dehydrogenase 0.0107 0.216 0.4393
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0015 0.0063 0.0004
Trypanosoma brucei glucose transporter, putative 0.0033 0.0479 0.2433
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0119 0.2431 0.4963
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0093 0.1849 0.2444
Mycobacterium tuberculosis Conserved protein 0.0035 0.0527 0.0963
Brugia malayi latrophilin 2 splice variant baaae 0.0137 0.2841 0.532
Brugia malayi Pre-SET motif family protein 0.003 0.0405 0.0759
Schistosoma mansoni hypothetical protein 0.0041 0.0652 0.1928
Loa Loa (eye worm) hypothetical protein 0.0015 0.0069 0.0079
Trypanosoma cruzi trypanothione reductase, putative 0.0047 0.0794 0.4271
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0016 0.0098 0.0219
Schistosoma mansoni hypothetical protein 0.0041 0.0652 0.1928
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0069 0.0016
Trichomonas vaginalis sugar transporter, putative 0.0033 0.0479 0.083
Echinococcus multilocularis Smad4 0.0017 0.0111 0.0069
Brugia malayi hypothetical protein 0.0149 0.3122 0.5845
Loa Loa (eye worm) hypothetical protein 0.0042 0.0686 0.1242
Giardia lamblia Lysyl-tRNA synthetase 0.0024 0.0268 0.3077
Echinococcus granulosus synaptic vesicle 2 protein 0.0015 0.0069 0.0011
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0069 0.0016
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0405 0.0518
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0069 0.0016
Trypanosoma brucei glucose transporter, putative 0.0033 0.0479 0.2433
Onchocerca volvulus 0.0035 0.0527 0.0911
Mycobacterium leprae conserved hypothetical protein 0.0035 0.0527 0.1515
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0016 0.0098 0.0051
Trypanosoma cruzi hexose transporter, putative 0.0033 0.0479 0.2433
Trypanosoma cruzi sugar transporter, putative 0.0015 0.0069 0.0048
Loa Loa (eye worm) hypothetical protein 0.0015 0.0069 0.0079
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0107 0.216 0.4393
Echinococcus multilocularis tumor protein p63 0.0336 0.7378 1
Trypanosoma brucei glucose transporter, putative 0.0033 0.0479 0.2433
Trypanosoma cruzi glucose transporter, putative 0.0015 0.0069 0.0048
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.009 0.1779 1
Trichomonas vaginalis esterase, putative 0.0035 0.0527 0.0926
Schistosoma mansoni hypothetical protein 0.0063 0.1169 0.3616
Schistosoma mansoni hypothetical protein 0.0137 0.2841 0.9067
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0464 0.0802
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.0718 0.1305
Loa Loa (eye worm) hypothetical protein 0.0137 0.2841 0.5296
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0069 0.0016
Schistosoma mansoni serine/threonine protein kinase 0.009 0.1779 0.5604
Plasmodium falciparum glutathione reductase 0.0047 0.0794 0.0731
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0016 0.0098 0.0184
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0032 0.0454 0.085
Loa Loa (eye worm) Smad1 0.0017 0.0111 0.0159
Loa Loa (eye worm) hypothetical protein 0.0088 0.1722 0.3191
Brugia malayi Thioredoxin reductase 0.0047 0.0794 0.1487
Loa Loa (eye worm) hypothetical protein 0.0015 0.0069 0.0079
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0098 0.0219
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0016 0.0098 0.0045
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0043 0.0718 0.1344
Loa Loa (eye worm) major facilitator superfamily transporter 0.0015 0.0069 0.0079
Loa Loa (eye worm) hypothetical protein 0.0035 0.0527 0.0942
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.0098 0.0219
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0106 0.2146 0.2851
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0032 0.0454 0.085
Toxoplasma gondii target of rapamycin (TOR), putative 0.0032 0.0464 0.0609
Loa Loa (eye worm) hypothetical protein 0.0015 0.0069 0.0079
Loa Loa (eye worm) hypothetical protein 0.0098 0.196 0.3638
Loa Loa (eye worm) hypothetical protein 0.0035 0.0527 0.0942
Echinococcus multilocularis thioredoxin glutathione reductase 0.0047 0.0794 0.1003
Loa Loa (eye worm) hypothetical protein 0.0024 0.0268 0.0455
Echinococcus multilocularis solute carrier family 22 0.0015 0.0069 0.0011
Trichomonas vaginalis PIKK family atypical protein kinase 0.0023 0.0263 0.0402
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0024 0.0268 0.4358
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0224 0.4828 1
Trypanosoma cruzi hexose transporter, putative 0.0018 0.0139 0.0455
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0033 0.0479 0.0898
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0527 0.0926
Trichomonas vaginalis sugar transport protein, putative 0.0015 0.0069 0.0016
Brugia malayi MH2 domain containing protein 0.0017 0.0111 0.0208
Loa Loa (eye worm) hypothetical protein 0.0052 0.0902 0.1647
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0069 0.0016
Plasmodium falciparum calcium-dependent protein kinase 2 0.0033 0.048 0.0414
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0069 0.0016
Mycobacterium tuberculosis Probable oxidoreductase 0.0119 0.2431 0.4963
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0515 0.0903
Toxoplasma gondii ABC1 family protein 0.0035 0.0527 0.0705
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0069 0.0016
Loa Loa (eye worm) MH2 domain-containing protein 0.0017 0.0111 0.0159
Trichomonas vaginalis conserved hypothetical protein 0.0106 0.2146 0.4141
Echinococcus multilocularis calcium dependent protein kinase 0.0031 0.0423 0.0496
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.003 0.0405 0.1125
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0035 0.0516 0.2652
Trypanosoma cruzi hexose transporter, putative 0.0033 0.0479 0.2433
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0098 0.0219
Schistosoma mansoni niemann-pick C1 (NPC1) 0.01 0.1995 0.6307
Schistosoma mansoni smad1 5 8 and 0.0017 0.0111 0.0165
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0063 0.1169 0.1516
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.009 0.1779 1
Echinococcus multilocularis lamin dm0 0.003 0.0421 0.0493
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0069 0.0016
Leishmania major lysyl-tRNA synthetase, putative 0.0024 0.0268 0.121
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0314 0.0503
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0016 0.01 0.0138
Loa Loa (eye worm) hypothetical protein 0.0035 0.0527 0.0942
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0037 0.0574 0.299
Loa Loa (eye worm) hypothetical protein 0.0015 0.0069 0.0079
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0033 0.0479 0.0573
Loa Loa (eye worm) MH2 domain-containing protein 0.0247 0.5341 1
Brugia malayi major facilitator superfamily protein 0.0015 0.0069 0.0129
Echinococcus granulosus lysyl tRNA synthetase 0.0024 0.0268 0.0284
Brugia malayi Major Facilitator Superfamily protein 0.0015 0.0069 0.0129
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0069 0.0016
Brugia malayi lysyl-tRNA synthetase 0.0024 0.0268 0.0502
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0024 0.0268 0.121
Loa Loa (eye worm) transcription factor SMAD2 0.0247 0.5341 1
Schistosoma mansoni glucose transport protein 0.0106 0.2146 0.6801
Schistosoma mansoni protein kinase 0.0033 0.0479 0.1366
Trichomonas vaginalis glucose transporter, putative 0.0033 0.0479 0.083
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0016 0.0098 0.003
Trypanosoma brucei glucose transporter, putative 0.0033 0.0479 0.2433
Mycobacterium tuberculosis Probable lipase LipD 0.0035 0.0527 0.0963
Plasmodium falciparum hexose transporter 0.0106 0.2146 0.2092
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0037 0.0574 0.299
Plasmodium vivax glutathione reductase, putative 0.0047 0.0794 0.0731
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.003 0.0421 0.0743
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0405 0.0471
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0032 0.0454 0.119
Onchocerca volvulus 0.003 0.0421 0.0702
Loa Loa (eye worm) hypothetical protein 0.0026 0.0318 0.0549
Entamoeba histolytica protein kinase domain containing protein 0.009 0.1779 0.893
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0093 0.1849 0.583
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0405 0.1125
Onchocerca volvulus 0.0149 0.3122 0.6072
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0479 0.083
Echinococcus multilocularis solute carrier family 22 0.0015 0.0069 0.0011
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0686 0.1243
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0024 0.0268 0.0362
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0119 0.2431 0.4963
Leishmania major myo-inositol/proton symporter (MIT) 0.0015 0.0069 0.0048
Loa Loa (eye worm) hypothetical protein 0.003 0.0409 0.0719
Brugia malayi Niemann-Pick C1 protein precursor 0.0098 0.196 0.367
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0119 0.2431 1
Leishmania major trypanothione reductase 0.0047 0.0794 0.4271
Echinococcus granulosus solute carrier family 22 0.0015 0.0069 0.0011
Brugia malayi Latrophilin receptor protein 2 0.0063 0.1169 0.2189
Loa Loa (eye worm) MH1 domain-containing protein 0.0017 0.0111 0.0159
Echinococcus multilocularis GPCR, family 2 0.0063 0.1169 0.1516
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0106 0.2146 0.2851
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0106 0.2146 0.2851
Echinococcus granulosus solute carrier family 22 0.0015 0.0069 0.0011
Echinococcus granulosus tumor protein p63 0.0336 0.7378 1
Brugia malayi MH2 domain containing protein 0.0247 0.5341 1
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0106 0.2146 0.2851
Echinococcus granulosus intermediate filament protein 0.003 0.0421 0.0493
Loa Loa (eye worm) hypothetical protein 0.0035 0.0527 0.0942
Trypanosoma cruzi target of rapamycin kinase 3 0.0035 0.0516 0.2652
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0033 0.048 0.0414
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0107 0.216 0.4393
Leishmania major protein kinase, putative 0.0033 0.0479 0.2438
Toxoplasma gondii lysine-tRNA ligase 0.0024 0.0268 0.0307
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0043 0.0718 0.3825
Echinococcus granulosus lamin dm0 0.003 0.0421 0.0493
Echinococcus granulosus solute carrier family 22 0.0015 0.0069 0.0011
Loa Loa (eye worm) hypothetical protein 0.0014 0.005 0.0045
Onchocerca volvulus 0.0049 0.0848 0.155
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0069 0.0016
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0093 0.1849 0.583
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0573 0.1018
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.0098 0.0219
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0069 0.0016
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0043 0.0718 0.2656
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0093 0.1849 0.2444
Mycobacterium leprae Probable lipase LipE 0.0035 0.0527 0.1515
Trichomonas vaginalis sugar transporter, putative 0.0033 0.0479 0.083
Brugia malayi Sugar transporter family protein 0.0015 0.0069 0.0129
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0016 0.0098 0.0062
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0069 0.0016
Plasmodium vivax proline--tRNA ligase, putative 0.0037 0.0574 0.0509
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0033 0.0479 0.0573
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0527 0.0926
Brugia malayi major facilitator superfamily protein 0.0015 0.0069 0.0129
Echinococcus granulosus General substrate transporter 0.0091 0.1806 0.2386
Loa Loa (eye worm) hypothetical protein 0.0015 0.0063 0.0069
Plasmodium falciparum glutathione reductase 0.0016 0.0098 0.003
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.0015 0.0069 0.0048
Echinococcus granulosus expressed conserved protein 0.0092 0.1825 0.2411
Trypanosoma cruzi hexose transporter, putative 0.0033 0.0479 0.2433
Schistosoma mansoni protein kinase 0.0033 0.0479 0.1366
Echinococcus multilocularis lamin 0.003 0.0421 0.0493
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0098 0.0219
Plasmodium vivax SET domain protein, putative 0.003 0.0405 0.0339
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0021 0.0202 0.0281
Brugia malayi Major Facilitator Superfamily protein 0.0015 0.0069 0.0129
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0464 0.0802
Loa Loa (eye worm) hypothetical protein 0.0049 0.0848 0.1546
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0015 0.0063 0.0004
Onchocerca volvulus 0.0035 0.0527 0.0911
Brugia malayi hypothetical protein 0.0015 0.0069 0.0129
Treponema pallidum NADH oxidase 0.0016 0.0098 0.5
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0069 0.0016
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0098 0.0219
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0032 0.0454 0.1098
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0069 0.0016
Brugia malayi Calcitonin receptor-like protein seb-1 0.02 0.4282 0.8017
Echinococcus multilocularis dual specificity 0.009 0.1779 0.2349
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0037 0.0574 0.299
Schistosoma mansoni glucose transporter 0.0015 0.0069 0.0027
Loa Loa (eye worm) hypothetical protein 0.0035 0.0527 0.0942
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0069 0.0016
Leishmania major glucose transporter/membrane transporter D2, putative 0.0033 0.0479 0.2433
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0063 0.1169 0.1516
Brugia malayi beta-lactamase family protein 0.0035 0.0527 0.0986
Loa Loa (eye worm) hypothetical protein 0.0015 0.0069 0.0079
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0069 0.0016
Mycobacterium tuberculosis Conserved protein 0.0035 0.0527 0.0963
Echinococcus granulosus beta LACTamase domain containing family member 0.0035 0.0527 0.0638
Leishmania major glucose transporter, lmgt1 0.0033 0.0479 0.2433
Echinococcus multilocularis musashi 0.003 0.0421 0.0493
Schistosoma mansoni hypothetical protein 0.0041 0.0652 0.1928
Schistosoma mansoni serine/threonine protein kinase 0.0033 0.0479 0.1366
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0093 0.1849 0.2444
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0107 0.216 0.8791
Schistosoma mansoni lamin 0.003 0.0421 0.1177
Echinococcus granulosus thioredoxin glutathione reductase 0.0047 0.0794 0.1003
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0043 0.0718 0.3825
Loa Loa (eye worm) major facilitator superfamily transporter 0.0015 0.0069 0.0079
Schistosoma mansoni intermediate filament proteins 0.003 0.0421 0.1177
Loa Loa (eye worm) hypothetical protein 0.0015 0.0069 0.0079
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0093 0.1849 0.2444
Loa Loa (eye worm) glutathione reductase 0.0047 0.0794 0.1445
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0033 0.0479 0.0573
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0106 0.2146 0.2851
Brugia malayi beta-lactamase family protein 0.0035 0.0527 0.0986
Echinococcus granulosus histone lysine methyltransferase setb 0.003 0.0405 0.0471
Plasmodium falciparum calcium-dependent protein kinase 3 0.0033 0.048 0.0414
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0106 0.2146 0.2851
Trichomonas vaginalis PIKK family atypical protein kinase 0.0023 0.0262 0.04
Echinococcus granulosus Niemann Pick C1 protein 0.014 0.2918 0.3905
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.009 0.1779 1
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0033 0.0479 0.0573
Onchocerca volvulus 0.003 0.0421 0.0702
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0037 0.0574 0.0778
Onchocerca volvulus 0.0035 0.0527 0.0911
Trypanosoma brucei THT1 - hexose transporter, putative 0.0033 0.0479 0.2433
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0069 0.0016
Plasmodium vivax hexose transporter 0.0106 0.2146 0.2092
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0033 0.048 0.0632
Leishmania major glucose transporter, lmgt3 0.0033 0.0479 0.2433
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0069 0.0016
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0035 0.0527 0.0963
Brugia malayi Sugar transporter family protein 0.0015 0.0069 0.0129
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0069 0.0016
Trypanosoma brucei glucose transporter, putative 0.0033 0.0479 0.2433
Toxoplasma gondii facilitative glucose transporter GT1 0.0106 0.2146 0.3196
Loa Loa (eye worm) hypothetical protein 0.0015 0.0069 0.0079
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0035 0.0527 0.0963
Entamoeba histolytica protein kinase, putative 0.0033 0.0479 0.1247
Plasmodium falciparum lysine--tRNA ligase 0.0024 0.0268 0.0201
Chlamydia trachomatis lysine--tRNA ligase 0.0024 0.0268 1
Brugia malayi Protein kinase domain containing protein 0.009 0.1779 0.3331
Trypanosoma brucei THT1 - hexose transporter, putative 0.0033 0.0479 0.2433
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0015 0.0069 0.0027
Giardia lamblia NADH oxidase lateral transfer candidate 0.0016 0.0098 0.0452
Trypanosoma brucei glucose transporter, putative 0.0033 0.0479 0.2433
Brugia malayi hypothetical protein 0.0015 0.0069 0.0129
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0515 0.0903
Brugia malayi MH2 domain containing protein 0.0017 0.0111 0.0208
Echinococcus multilocularis expressed conserved protein 0.0092 0.1825 0.2411
Leishmania major glucose transporter, lmgt2 0.0033 0.0479 0.2433
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0043 0.0718 0.3825
Schistosoma mansoni hypothetical protein 0.0106 0.2146 0.6801
Plasmodium vivax hypothetical protein, conserved 0.0035 0.0527 0.0461
Loa Loa (eye worm) hypothetical protein 0.0015 0.0069 0.0079
Plasmodium falciparum protein kinase 7 0.0301 0.657 0.6546
Plasmodium falciparum proline--tRNA ligase 0.0037 0.0574 0.0509
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0035 0.0527 0.0963
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0018 0.014 0.046
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0016 0.0098 0.0123
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0107 0.216 0.4393
Plasmodium falciparum calcium-dependent protein kinase 4 0.0033 0.048 0.0414
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0024 0.0268 0.4358
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0069 0.0016
Plasmodium vivax thioredoxin reductase, putative 0.0047 0.0794 0.0731
Trichomonas vaginalis mercuric reductase, putative 0.0016 0.0098 0.0075
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0107 0.216 0.4393
Echinococcus multilocularis Niemann Pick C1 protein 0.0098 0.196 0.2596
Loa Loa (eye worm) beta-lactamase 0.0035 0.0527 0.0942
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0063 0.1169 0.2189
Toxoplasma gondii protein kinase, putative 0.0301 0.657 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0464 0.0802
Trichomonas vaginalis set domain proteins, putative 0.0236 0.5097 1
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0037 0.0574 0.299
Mycobacterium ulcerans hypothetical protein 0.0035 0.0527 1
Brugia malayi Smad1 0.0017 0.0111 0.0208
Echinococcus granulosus calcium dependent protein kinase 0.0031 0.0423 0.0496
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0043 0.0718 0.3825
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0098 0.0219
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0032 0.0454 0.0538
Loa Loa (eye worm) hypothetical protein 0.0015 0.0069 0.0079
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0021 0.0196 0.0792
Mycobacterium ulcerans lipase LipD 0.0035 0.0527 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0023 0.0263 0.0402
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.002 0.0187 0.0249
Brugia malayi Major Facilitator Superfamily protein 0.0015 0.0069 0.0129
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0069 0.0016
Echinococcus multilocularis General substrate transporter 0.0091 0.1806 0.2386
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0069 0.0016
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.032 0.0515
Schistosoma mansoni smad1 5 8 and 0.0017 0.0111 0.0165
Loa Loa (eye worm) phosphatidylinositol 3 0.0015 0.006 0.0064
Echinococcus multilocularis protein patched 0.0042 0.0686 0.0855
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0069 0.0016
Echinococcus multilocularis solute carrier family 22 0.0015 0.0069 0.0011
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0069 0.0016
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0314 0.0503
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.009 0.1779 1
Schistosoma mansoni lysyl-tRNA synthetase 0.0024 0.0268 0.0678
Trypanosoma brucei glucose transporter, putative 0.0033 0.0479 0.2433
Brugia malayi beta-lactamase 0.0035 0.0527 0.0986
Mycobacterium tuberculosis Conserved protein 0.0035 0.0527 0.0963
Trichomonas vaginalis PIKK family atypical protein kinase 0.0023 0.0262 0.04
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0515 0.0903
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0016 0.0098 0.0051
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0016 0.0098 0.0219
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0016 0.0098 0.0219
Echinococcus granulosus GPCR family 2 0.0063 0.1169 0.1516
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0515 0.0903
Entamoeba histolytica protein kinase, putative 0.009 0.1779 0.893
Mycobacterium tuberculosis Probable lipase LipE 0.0035 0.0527 0.0963
Giardia lamblia Prolyl-tRNA synthetase 0.0032 0.0454 0.5937
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0093 0.1849 0.3461
Trichomonas vaginalis glucose transporter, putative 0.0015 0.0069 0.0016
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0033 0.0479 0.0852
Trypanosoma brucei hypothetical protein, conserved 0.0035 0.0527 0.2714
Schistosoma mansoni glucose transport protein 0.0106 0.2146 0.6801
Mycobacterium tuberculosis Probable esterase LipL 0.0035 0.0527 0.0963
Loa Loa (eye worm) hypothetical protein 0.0035 0.0527 0.0942
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0017 0.0111 0.0165
Echinococcus granulosus sterol regulatory element binding protein 0.0042 0.0686 0.0855
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0035 0.0527 0.0986
Loa Loa (eye worm) hypothetical protein 0.0033 0.0479 0.0852
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.003 0.0405 0.0471
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0016 0.0098 1
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0043 0.0718 0.2656
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0015 0.006 0.0113
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0024 0.0268 0.0413
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0033 0.048 0.0632
Schistosoma mansoni protein kinase 0.0033 0.0479 0.1366
Echinococcus multilocularis lysyl tRNA synthetase 0.0024 0.0268 0.0284
Trypanosoma cruzi hexose transporter, putative 0.0015 0.0069 0.0048
Trypanosoma brucei THT1 - hexose transporter, putative 0.0033 0.0479 0.2433
Echinococcus multilocularis solute carrier family 22 0.0015 0.0069 0.0011
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0043 0.0718 0.3825
Toxoplasma gondii NADPH-glutathione reductase 0.0016 0.0098 0.0045
Entamoeba histolytica protein kinase, putative 0.0033 0.0479 0.1247
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0207 0.4446 0.8315
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0032 0.0454 0.0782
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0527 0.1521
Schistosoma mansoni sugar transporter 0.0015 0.0069 0.0027
Plasmodium vivax CDK-related protein kinase 6, putative 0.0451 1 1
Echinococcus multilocularis smad 0.0017 0.0111 0.0069
Mycobacterium ulcerans beta-lactamase 0.0035 0.0527 1
Echinococcus multilocularis Niemann Pick C1 protein 0.014 0.2918 0.3905
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.009 0.1779 0.3298
Plasmodium falciparum calcium-dependent protein kinase 1 0.0033 0.048 0.0414
Schistosoma mansoni lysyl-tRNA synthetase 0.0024 0.0268 0.0678
Loa Loa (eye worm) pigment dispersing factor receptor c 0.02 0.4282 0.8007
Brugia malayi intermediate filament protein 0.003 0.0421 0.0789
Echinococcus multilocularis beta LACTamase domain containing family member 0.0035 0.0527 0.0638
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0069 0.0016
Brugia malayi hypothetical protein 0.0015 0.0069 0.0129
Trichomonas vaginalis glucose transporter, putative 0.0033 0.0479 0.083
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0035 0.0516 0.2652
Plasmodium vivax lysine--tRNA ligase, putative 0.0024 0.0268 0.0201
Trichomonas vaginalis sugar transporter, putative 0.0033 0.0479 0.083
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0016 0.0098 0.0641
Loa Loa (eye worm) hypothetical protein 0.003 0.0421 0.0743
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0037 0.0574 0.299
Echinococcus multilocularis synaptic vesicle 2 protein 0.0015 0.0069 0.0011
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0042 0.0686 0.1242
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0069 0.0016
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0033 0.048 0.0414
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0069 0.0016
Schistosoma mansoni hypothetical protein 0.0063 0.1169 0.3616
Brugia malayi Cam kinase protein 1 0.0033 0.0479 0.0898
Leishmania major hypothetical protein, conserved 0.0035 0.0527 0.2714
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0016 0.0098 0.0641
Brugia malayi MH1 domain containing protein 0.0017 0.0111 0.0208
Echinococcus granulosus smad 0.0017 0.0111 0.0069
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0371 0.0616
Plasmodium falciparum thioredoxin reductase 0.0047 0.0794 0.0731
Echinococcus multilocularis protein dispatched 1 0.0048 0.0822 0.104
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0032 0.0454 0.1284
Loa Loa (eye worm) hypothetical protein 0.0149 0.3122 0.5824
Plasmodium falciparum mitogen-activated protein kinase 2 0.0172 0.3646 0.3602
Loa Loa (eye worm) hypothetical protein 0.0088 0.1722 0.3191
Trichomonas vaginalis glutathione reductase, putative 0.0016 0.0098 0.0075
Loa Loa (eye worm) hypothetical protein 0.0015 0.0069 0.0079
Schistosoma mansoni Smad4 0.0017 0.0111 0.0165
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0016 0.0098 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0023 0.0263 0.0402
Mycobacterium tuberculosis Probable hydrolase 0.0035 0.0527 0.0963
Echinococcus granulosus Sugar transporter ERD6 protein 0.0015 0.0069 0.0011
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0464 0.0802
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0527 0.0926
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.032 0.0515
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0069 0.0016
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0063 0.1169 0.1516
Echinococcus granulosus dual specificity 0.009 0.1779 0.2349
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0069 0.0016
Schistosoma mansoni cellular tumor antigen P53 0.0049 0.0848 0.2569
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0016 0.0098 0.003
Onchocerca volvulus 0.003 0.0405 0.0669
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0069 0.0016
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0035 0.0527 1
Loa Loa (eye worm) intermediate filament protein 0.003 0.0421 0.0743
Schistosoma mansoni sugar transporter 0.0015 0.0069 0.0027
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0093 0.1849 0.3428
Brugia malayi Intermediate filament tail domain containing protein 0.003 0.0421 0.0789
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0106 0.2146 0.2851
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0172 0.3646 0.5502
Onchocerca volvulus 0.0236 0.5097 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.032 0.0515
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0033 0.0479 0.0852
Trypanosoma brucei glucose transporter 2A 0.0033 0.0479 0.2433
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0069 0.0016
Trichomonas vaginalis PIKK family atypical protein kinase 0.0023 0.0263 0.0402
Mycobacterium tuberculosis Probable reductase 0.0107 0.216 0.4393
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0033 0.048 0.0414
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0527 0.1521
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0016 0.0098 0.003
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0069 0.0016
Brugia malayi Pre-SET motif family protein 0.0207 0.4446 0.8323
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0024 0.0268 0.121
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0033 0.048 0.0632
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0016 0.0098 0.003
Brugia malayi cytoplasmic intermediate filament protein 0.0016 0.01 0.0187
Plasmodium vivax calcium-dependent protein kinase, putative 0.0033 0.048 0.0414
Schistosoma mansoni smad1 5 8 and 0.0017 0.0111 0.0165
Loa Loa (eye worm) latrophilin receptor protein 2 0.0063 0.1169 0.2151
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0069 0.0016
Schistosoma mansoni smad 0.0017 0.0111 0.0165
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0098 0.196 1
Trypanosoma brucei sugar transporter, putative 0.0015 0.0069 0.0048
Echinococcus granulosus mothers against decapentaplegic 5 0.0017 0.0111 0.0069
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0043 0.0718 0.0898
Loa Loa (eye worm) hypothetical protein 0.02 0.4282 0.8007
Trypanosoma brucei trypanothione reductase 0.0047 0.0794 0.4271
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0479 0.083
Schistosoma mansoni hypothetical protein 0.0041 0.0652 0.1928
Trypanosoma cruzi trypanothione reductase, putative 0.0016 0.0098 0.0219
Loa Loa (eye worm) hypothetical protein 0.0032 0.0454 0.0805
Schistosoma mansoni lamin 0.003 0.0421 0.1177
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.02 0.4282 0.8017
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0093 0.1849 0.583
Loa Loa (eye worm) hypothetical protein 0.0063 0.1169 0.2151
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0043 0.0718 0.0898
Giardia lamblia GTOR 0.0043 0.0718 1
Brugia malayi glutathione reductase 0.0047 0.0794 0.1487
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.0098 0.0219
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0405 0.1125
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0098 0.0219
Echinococcus multilocularis mothers against decapentaplegic 5 0.0017 0.0111 0.0069
Echinococcus granulosus TGF beta signal transducer SmadC 0.0017 0.0111 0.0069
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0016 0.0098 0.0641
Schistosoma mansoni hypothetical protein 0.0063 0.1169 0.3616
Loa Loa (eye worm) hypothetical protein 0.0015 0.0069 0.0079
Loa Loa (eye worm) phosphatidylinositol 3 0.0043 0.0718 0.1301
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0047 0.0794 0.1525
Loa Loa (eye worm) hypothetical protein 0.0014 0.005 0.0045
Entamoeba histolytica protein kinase, putative 0.009 0.1779 0.893
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0033 0.0479 0.0573
Loa Loa (eye worm) hypothetical protein 0.0015 0.0069 0.0079
Schistosoma mansoni patched 1 0.0042 0.0686 0.2041
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0033 0.0479 0.0573
Brugia malayi CHE-14 protein 0.0042 0.0686 0.1285
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0016 0.0098 0.0219
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0527 0.2714
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0015 0.0069 0.0011
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0063 0.1169 0.1516
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0032 0.0454 0.1284
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0098 0.0219
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0069 0.0016
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0069 0.0016
Plasmodium falciparum thioredoxin reductase 0.0016 0.0098 0.003
Echinococcus granulosus Smad4 0.0017 0.0111 0.0069
Trichomonas vaginalis myo-inositol transporter, putative 0.0015 0.0069 0.0016
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0106 0.2146 0.2851
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0405 0.1125
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.0098 0.0219
Trichomonas vaginalis CAMK family protein kinase 0.0033 0.0479 0.0832
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0033 0.0479 0.2438
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0069 0.0016
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0464 0.0802
Trypanosoma brucei glucose transporter 1E 0.0033 0.0479 0.2433
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.002 0.0187 0.0249
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0035 0.0527 0.0942
Echinococcus granulosus Niemann Pick C1 protein 0.0098 0.196 0.2596
Leishmania major hypothetical protein, conserved 0.0015 0.0069 0.0048
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0017 0.0111 0.0069
Echinococcus granulosus solute carrier family 22 0.0015 0.0069 0.0011
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0033 0.0479 0.0573
Loa Loa (eye worm) thioredoxin reductase 0.0047 0.0794 0.1445
Mycobacterium ulcerans esterase/lipase LipP 0.0035 0.0527 1
Toxoplasma gondii thioredoxin reductase 0.0047 0.0794 0.1116
Loa Loa (eye worm) hypothetical protein 0.003 0.0405 0.0713
Loa Loa (eye worm) sugar transporter 0.0106 0.2146 0.3989
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0527 0.2714
Brugia malayi Sugar transporter family protein 0.0106 0.2146 0.4018
Echinococcus multilocularis sterol regulatory element binding protein 0.0042 0.0686 0.0855
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.0718 0.1305
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0069 0.0016
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0527 0.0926
Trypanosoma brucei glucose transporter, putative 0.0033 0.0479 0.2433
Schistosoma mansoni sugar transporter 0.0015 0.0069 0.0027
Trypanosoma cruzi hexose transporter 0.0033 0.0479 0.2433
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0043 0.0718 0.2143
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0515 0.0903
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0464 0.0802
Loa Loa (eye worm) hypothetical protein 0.0032 0.0454 0.0805
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0069 0.0016
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0098 0.0219
Loa Loa (eye worm) hypothetical protein 0.0015 0.0069 0.0079

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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