Detailed information for compound 540017

Basic information

Technical information
  • TDR Targets ID: 540017
  • Name: [4,5-di(butanoyloxy)-2-(butanoyloxymethyl)-1- butyl-3-piperidyl] butanoate
  • MW: 499.637 | Formula: C26H45NO8
  • H donors: 0 H acceptors: 4 LogP: 4.42 Rotable bonds: 20
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCCN1CC(OC(=O)CCC)C(C(C1COC(=O)CCC)OC(=O)CCC)OC(=O)CCC
  • InChi: 1S/C26H45NO8/c1-6-11-16-27-17-20(33-22(29)13-8-3)26(35-24(31)15-10-5)25(34-23(30)14-9-4)19(27)18-32-21(28)12-7-2/h19-20,25-26H,6-18H2,1-5H3
  • InChiKey: MKGDNVHZSCXBKR-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • butanoic acid [1-butyl-4,5-bis(1-oxobutoxy)-2-(1-oxobutoxymethyl)-3-piperidinyl] ester
  • [4,5-di(butanoyloxy)-2-(butanoyloxymethyl)-1-butyl-piperidin-3-yl] butanoate
  • butyric acid [1-butyl-4,5-dibutyryloxy-2-(butyryloxymethyl)-3-piperidyl] ester
  • [4,5-di(butanoyloxy)-2-(butanoyloxymethyl)-1-butylpiperidin-3-yl] butanoate
  • glycovir
  • {1-Butyl-2R,2.alpha.-[(1-oxybutoxy)methyl]-3.beta.,4.alpha.,} 5.beta.-piperidinetriyl butanoate
  • 1,5-(Butylimino)-1-5-dideoxy-D-glucitol tetrabutanoate
  • 1-Butyl-3,5-bis(butyryloxy)-2-((butyryloxy)methyl)-4-piperidinyl butyrate
  • AIDS-145666
  • AIDS145666
  • N-Butyl DNJ Prodrug
  • NSC670880
  • SC-48334 Prodrug
  • SC49483

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus Sugar transporter ERD6 protein 0.0015 0.0069 0.0011
Mycobacterium tuberculosis Probable hydrolase 0.0035 0.0527 0.0963
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0527 0.0926
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.032 0.0515
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0464 0.0802
Loa Loa (eye worm) hypothetical protein 0.0015 0.0069 0.0079
Schistosoma mansoni Smad4 0.0017 0.0111 0.0165
Loa Loa (eye worm) hypothetical protein 0.0088 0.1722 0.3191
Trichomonas vaginalis glutathione reductase, putative 0.0016 0.0098 0.0075
Trichomonas vaginalis PIKK family atypical protein kinase 0.0023 0.0263 0.0402
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0016 0.0098 1
Schistosoma mansoni cellular tumor antigen P53 0.0049 0.0848 0.2569
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0069 0.0016
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0063 0.1169 0.1516
Echinococcus granulosus dual specificity 0.009 0.1779 0.2349
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0069 0.0016
Brugia malayi Cam kinase protein 1 0.0033 0.0479 0.0898
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0016 0.0098 0.0641
Leishmania major hypothetical protein, conserved 0.0035 0.0527 0.2714
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0033 0.048 0.0414
Schistosoma mansoni hypothetical protein 0.0063 0.1169 0.3616
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0069 0.0016
Plasmodium falciparum mitogen-activated protein kinase 2 0.0172 0.3646 0.3602
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0032 0.0454 0.1284
Loa Loa (eye worm) hypothetical protein 0.0149 0.3122 0.5824
Echinococcus granulosus smad 0.0017 0.0111 0.0069
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0371 0.0616
Brugia malayi MH1 domain containing protein 0.0017 0.0111 0.0208
Echinococcus multilocularis protein dispatched 1 0.0048 0.0822 0.104
Plasmodium falciparum thioredoxin reductase 0.0047 0.0794 0.0731
Echinococcus granulosus mothers against decapentaplegic 5 0.0017 0.0111 0.0069
Loa Loa (eye worm) hypothetical protein 0.02 0.4282 0.8007
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0043 0.0718 0.0898
Plasmodium vivax calcium-dependent protein kinase, putative 0.0033 0.048 0.0414
Schistosoma mansoni smad1 5 8 and 0.0017 0.0111 0.0165
Brugia malayi cytoplasmic intermediate filament protein 0.0016 0.01 0.0187
Schistosoma mansoni smad 0.0017 0.0111 0.0165
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0098 0.196 1
Trypanosoma brucei sugar transporter, putative 0.0015 0.0069 0.0048
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0069 0.0016
Loa Loa (eye worm) latrophilin receptor protein 2 0.0063 0.1169 0.2151
Schistosoma mansoni lamin 0.003 0.0421 0.1177
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0093 0.1849 0.583
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.02 0.4282 0.8017
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0479 0.083
Trypanosoma brucei trypanothione reductase 0.0047 0.0794 0.4271
Loa Loa (eye worm) hypothetical protein 0.0032 0.0454 0.0805
Trypanosoma cruzi trypanothione reductase, putative 0.0016 0.0098 0.0219
Schistosoma mansoni hypothetical protein 0.0041 0.0652 0.1928
Onchocerca volvulus 0.0236 0.5097 1
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0172 0.3646 0.5502
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0093 0.1849 0.3428
Brugia malayi Intermediate filament tail domain containing protein 0.003 0.0421 0.0789
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0106 0.2146 0.2851
Schistosoma mansoni sugar transporter 0.0015 0.0069 0.0027
Loa Loa (eye worm) intermediate filament protein 0.003 0.0421 0.0743
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.032 0.0515
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0069 0.0016
Onchocerca volvulus 0.003 0.0405 0.0669
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0016 0.0098 0.003
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0035 0.0527 1
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0024 0.0268 0.121
Brugia malayi Pre-SET motif family protein 0.0207 0.4446 0.8323
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0016 0.0098 0.003
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0033 0.048 0.0632
Mycobacterium tuberculosis Probable reductase 0.0107 0.216 0.4393
Trichomonas vaginalis PIKK family atypical protein kinase 0.0023 0.0263 0.0402
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0069 0.0016
Trypanosoma brucei glucose transporter 2A 0.0033 0.0479 0.2433
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0033 0.0479 0.0852
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0069 0.0016
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0527 0.1521
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0016 0.0098 0.003
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0033 0.048 0.0414
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0527 0.2714
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0015 0.0069 0.0011
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0016 0.0098 0.0219
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0033 0.0479 0.0573
Brugia malayi CHE-14 protein 0.0042 0.0686 0.1285
Schistosoma mansoni patched 1 0.0042 0.0686 0.2041
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0032 0.0454 0.1284
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0063 0.1169 0.1516
Loa Loa (eye worm) hypothetical protein 0.0014 0.005 0.0045
Loa Loa (eye worm) hypothetical protein 0.0015 0.0069 0.0079
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0033 0.0479 0.0573
Entamoeba histolytica protein kinase, putative 0.009 0.1779 0.893
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0106 0.2146 0.2851
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.0098 0.0219
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0405 0.1125
Plasmodium falciparum thioredoxin reductase 0.0016 0.0098 0.003
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0069 0.0016
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0069 0.0016
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0098 0.0219
Echinococcus granulosus Smad4 0.0017 0.0111 0.0069
Trichomonas vaginalis myo-inositol transporter, putative 0.0015 0.0069 0.0016
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.0098 0.0219
Brugia malayi glutathione reductase 0.0047 0.0794 0.1487
Giardia lamblia GTOR 0.0043 0.0718 1
Echinococcus multilocularis mothers against decapentaplegic 5 0.0017 0.0111 0.0069
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0098 0.0219
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0405 0.1125
Loa Loa (eye worm) hypothetical protein 0.0063 0.1169 0.2151
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0043 0.0718 0.0898
Loa Loa (eye worm) hypothetical protein 0.0015 0.0069 0.0079
Loa Loa (eye worm) phosphatidylinositol 3 0.0043 0.0718 0.1301
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0047 0.0794 0.1525
Echinococcus granulosus TGF beta signal transducer SmadC 0.0017 0.0111 0.0069
Schistosoma mansoni hypothetical protein 0.0063 0.1169 0.3616
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0016 0.0098 0.0641
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0069 0.0016
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.0718 0.1305
Echinococcus multilocularis sterol regulatory element binding protein 0.0042 0.0686 0.0855
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0527 0.0926
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0527 0.2714
Loa Loa (eye worm) sugar transporter 0.0106 0.2146 0.3989
Loa Loa (eye worm) hypothetical protein 0.003 0.0405 0.0713
Toxoplasma gondii thioredoxin reductase 0.0047 0.0794 0.1116
Brugia malayi Sugar transporter family protein 0.0106 0.2146 0.4018
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0098 0.0219
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0069 0.0016
Loa Loa (eye worm) hypothetical protein 0.0032 0.0454 0.0805
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0464 0.0802
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0515 0.0903
Loa Loa (eye worm) hypothetical protein 0.0015 0.0069 0.0079
Trypanosoma brucei glucose transporter, putative 0.0033 0.0479 0.2433
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0043 0.0718 0.2143
Trypanosoma cruzi hexose transporter 0.0033 0.0479 0.2433
Schistosoma mansoni sugar transporter 0.0015 0.0069 0.0027
Trypanosoma brucei glucose transporter 1E 0.0033 0.0479 0.2433
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0464 0.0802
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.002 0.0187 0.0249
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0033 0.0479 0.2438
Trichomonas vaginalis CAMK family protein kinase 0.0033 0.0479 0.0832
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0069 0.0016
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0033 0.0479 0.0573
Echinococcus granulosus solute carrier family 22 0.0015 0.0069 0.0011
Leishmania major hypothetical protein, conserved 0.0015 0.0069 0.0048
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0017 0.0111 0.0069
Mycobacterium ulcerans esterase/lipase LipP 0.0035 0.0527 1
Loa Loa (eye worm) thioredoxin reductase 0.0047 0.0794 0.1445
Echinococcus granulosus Niemann Pick C1 protein 0.0098 0.196 0.2596
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0035 0.0527 0.0942
Plasmodium falciparum calcium-dependent protein kinase 4 0.0033 0.048 0.0414
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0107 0.216 0.4393
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0024 0.0268 0.4358
Plasmodium falciparum proline--tRNA ligase 0.0037 0.0574 0.0509
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0016 0.0098 0.0123
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0018 0.014 0.046
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0035 0.0527 0.0963
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0107 0.216 0.4393
Echinococcus multilocularis Niemann Pick C1 protein 0.0098 0.196 0.2596
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0069 0.0016
Trichomonas vaginalis mercuric reductase, putative 0.0016 0.0098 0.0075
Plasmodium vivax thioredoxin reductase, putative 0.0047 0.0794 0.0731
Brugia malayi Protein kinase domain containing protein 0.009 0.1779 0.3331
Giardia lamblia NADH oxidase lateral transfer candidate 0.0016 0.0098 0.0452
Trypanosoma brucei glucose transporter, putative 0.0033 0.0479 0.2433
Trypanosoma brucei THT1 - hexose transporter, putative 0.0033 0.0479 0.2433
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0015 0.0069 0.0027
Plasmodium falciparum lysine--tRNA ligase 0.0024 0.0268 0.0201
Chlamydia trachomatis lysine--tRNA ligase 0.0024 0.0268 1
Plasmodium vivax hypothetical protein, conserved 0.0035 0.0527 0.0461
Loa Loa (eye worm) hypothetical protein 0.0015 0.0069 0.0079
Schistosoma mansoni hypothetical protein 0.0106 0.2146 0.6801
Plasmodium falciparum protein kinase 7 0.0301 0.657 0.6546
Brugia malayi MH2 domain containing protein 0.0017 0.0111 0.0208
Echinococcus multilocularis expressed conserved protein 0.0092 0.1825 0.2411
Brugia malayi hypothetical protein 0.0015 0.0069 0.0129
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0515 0.0903
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0043 0.0718 0.3825
Leishmania major glucose transporter, lmgt2 0.0033 0.0479 0.2433
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.032 0.0515
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0069 0.0016
Echinococcus multilocularis General substrate transporter 0.0091 0.1806 0.2386
Schistosoma mansoni smad1 5 8 and 0.0017 0.0111 0.0165
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0069 0.0016
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0069 0.0016
Schistosoma mansoni lysyl-tRNA synthetase 0.0024 0.0268 0.0678
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.009 0.1779 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0314 0.0503
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0069 0.0016
Echinococcus multilocularis protein patched 0.0042 0.0686 0.0855
Loa Loa (eye worm) phosphatidylinositol 3 0.0015 0.006 0.0064
Echinococcus multilocularis solute carrier family 22 0.0015 0.0069 0.0011
Trichomonas vaginalis set domain proteins, putative 0.0236 0.5097 1
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0037 0.0574 0.299
Loa Loa (eye worm) beta-lactamase 0.0035 0.0527 0.0942
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0464 0.0802
Toxoplasma gondii protein kinase, putative 0.0301 0.657 1
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0063 0.1169 0.2189
Loa Loa (eye worm) hypothetical protein 0.0015 0.0069 0.0079
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0032 0.0454 0.0538
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0098 0.0219
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.002 0.0187 0.0249
Brugia malayi Major Facilitator Superfamily protein 0.0015 0.0069 0.0129
Trichomonas vaginalis PIKK family atypical protein kinase 0.0023 0.0263 0.0402
Mycobacterium ulcerans lipase LipD 0.0035 0.0527 1
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0021 0.0196 0.0792
Echinococcus granulosus calcium dependent protein kinase 0.0031 0.0423 0.0496
Brugia malayi Smad1 0.0017 0.0111 0.0208
Mycobacterium ulcerans hypothetical protein 0.0035 0.0527 1
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0043 0.0718 0.3825
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0093 0.1849 0.3461
Trypanosoma brucei hypothetical protein, conserved 0.0035 0.0527 0.2714
Trichomonas vaginalis glucose transporter, putative 0.0015 0.0069 0.0016
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0033 0.0479 0.0852
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.003 0.0405 0.0471
Loa Loa (eye worm) hypothetical protein 0.0033 0.0479 0.0852
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0043 0.0718 0.2656
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0016 0.0098 1
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0015 0.006 0.0113
Mycobacterium tuberculosis Probable esterase LipL 0.0035 0.0527 0.0963
Schistosoma mansoni glucose transport protein 0.0106 0.2146 0.6801
Echinococcus granulosus sterol regulatory element binding protein 0.0042 0.0686 0.0855
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0035 0.0527 0.0986
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0017 0.0111 0.0165
Loa Loa (eye worm) hypothetical protein 0.0035 0.0527 0.0942
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0016 0.0098 0.0219
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0016 0.0098 0.0051
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0016 0.0098 0.0219
Mycobacterium tuberculosis Conserved protein 0.0035 0.0527 0.0963
Brugia malayi beta-lactamase 0.0035 0.0527 0.0986
Trypanosoma brucei glucose transporter, putative 0.0033 0.0479 0.2433
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0515 0.0903
Trichomonas vaginalis PIKK family atypical protein kinase 0.0023 0.0262 0.04
Entamoeba histolytica protein kinase, putative 0.009 0.1779 0.893
Giardia lamblia Prolyl-tRNA synthetase 0.0032 0.0454 0.5937
Mycobacterium tuberculosis Probable lipase LipE 0.0035 0.0527 0.0963
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0515 0.0903
Echinococcus granulosus GPCR family 2 0.0063 0.1169 0.1516
Echinococcus multilocularis beta LACTamase domain containing family member 0.0035 0.0527 0.0638
Brugia malayi intermediate filament protein 0.003 0.0421 0.0789
Loa Loa (eye worm) pigment dispersing factor receptor c 0.02 0.4282 0.8007
Trichomonas vaginalis glucose transporter, putative 0.0033 0.0479 0.083
Brugia malayi hypothetical protein 0.0015 0.0069 0.0129
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0069 0.0016
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.009 0.1779 0.3298
Schistosoma mansoni lysyl-tRNA synthetase 0.0024 0.0268 0.0678
Plasmodium falciparum calcium-dependent protein kinase 1 0.0033 0.048 0.0414
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0069 0.0016
Echinococcus multilocularis synaptic vesicle 2 protein 0.0015 0.0069 0.0011
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0042 0.0686 0.1242
Trichomonas vaginalis sugar transporter, putative 0.0033 0.0479 0.083
Plasmodium vivax lysine--tRNA ligase, putative 0.0024 0.0268 0.0201
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0035 0.0516 0.2652
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0037 0.0574 0.299
Loa Loa (eye worm) hypothetical protein 0.003 0.0421 0.0743
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0016 0.0098 0.0641
Echinococcus multilocularis solute carrier family 22 0.0015 0.0069 0.0011
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0043 0.0718 0.3825
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0024 0.0268 0.0413
Trypanosoma brucei THT1 - hexose transporter, putative 0.0033 0.0479 0.2433
Trypanosoma cruzi hexose transporter, putative 0.0015 0.0069 0.0048
Echinococcus multilocularis lysyl tRNA synthetase 0.0024 0.0268 0.0284
Schistosoma mansoni protein kinase 0.0033 0.0479 0.1366
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0033 0.048 0.0632
Echinococcus multilocularis Niemann Pick C1 protein 0.014 0.2918 0.3905
Mycobacterium ulcerans beta-lactamase 0.0035 0.0527 1
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0032 0.0454 0.0782
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0207 0.4446 0.8315
Entamoeba histolytica protein kinase, putative 0.0033 0.0479 0.1247
Toxoplasma gondii NADPH-glutathione reductase 0.0016 0.0098 0.0045
Echinococcus multilocularis smad 0.0017 0.0111 0.0069
Plasmodium vivax CDK-related protein kinase 6, putative 0.0451 1 1
Schistosoma mansoni sugar transporter 0.0015 0.0069 0.0027
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0527 0.1521
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0024 0.0268 0.0362
Echinococcus multilocularis solute carrier family 22 0.0015 0.0069 0.0011
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0686 0.1243
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0479 0.083
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0119 0.2431 0.4963
Entamoeba histolytica protein kinase domain containing protein 0.009 0.1779 0.893
Loa Loa (eye worm) hypothetical protein 0.0026 0.0318 0.0549
Onchocerca volvulus 0.0149 0.3122 0.6072
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0093 0.1849 0.583
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0405 0.1125
Brugia malayi Latrophilin receptor protein 2 0.0063 0.1169 0.2189
Echinococcus multilocularis GPCR, family 2 0.0063 0.1169 0.1516
Loa Loa (eye worm) MH1 domain-containing protein 0.0017 0.0111 0.0159
Loa Loa (eye worm) hypothetical protein 0.003 0.0409 0.0719
Leishmania major myo-inositol/proton symporter (MIT) 0.0015 0.0069 0.0048
Echinococcus granulosus solute carrier family 22 0.0015 0.0069 0.0011
Leishmania major trypanothione reductase 0.0047 0.0794 0.4271
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0119 0.2431 1
Brugia malayi Niemann-Pick C1 protein precursor 0.0098 0.196 0.367
Schistosoma mansoni protein kinase 0.0033 0.0479 0.1366
Brugia malayi Major Facilitator Superfamily protein 0.0015 0.0069 0.0129
Schistosoma mansoni glucose transport protein 0.0106 0.2146 0.6801
Loa Loa (eye worm) transcription factor SMAD2 0.0247 0.5341 1
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0024 0.0268 0.121
Brugia malayi lysyl-tRNA synthetase 0.0024 0.0268 0.0502
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0069 0.0016
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.003 0.0421 0.0743
Plasmodium vivax glutathione reductase, putative 0.0047 0.0794 0.0731
Plasmodium falciparum hexose transporter 0.0106 0.2146 0.2092
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0037 0.0574 0.299
Onchocerca volvulus 0.003 0.0421 0.0702
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0032 0.0454 0.119
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0405 0.0471
Mycobacterium tuberculosis Probable lipase LipD 0.0035 0.0527 0.0963
Trypanosoma brucei glucose transporter, putative 0.0033 0.0479 0.2433
Trichomonas vaginalis glucose transporter, putative 0.0033 0.0479 0.083
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0016 0.0098 0.003
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0093 0.1849 0.2444
Trichomonas vaginalis sugar transporter, putative 0.0033 0.0479 0.083
Mycobacterium leprae Probable lipase LipE 0.0035 0.0527 0.1515
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0069 0.0016
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0043 0.0718 0.2656
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0069 0.0016
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0016 0.0098 0.0062
Brugia malayi Sugar transporter family protein 0.0015 0.0069 0.0129
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0573 0.1018
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.0098 0.0219
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.0015 0.0069 0.0048
Plasmodium falciparum glutathione reductase 0.0016 0.0098 0.003
Echinococcus granulosus expressed conserved protein 0.0092 0.1825 0.2411
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0033 0.0479 0.0573
Plasmodium vivax proline--tRNA ligase, putative 0.0037 0.0574 0.0509
Loa Loa (eye worm) hypothetical protein 0.0015 0.0063 0.0069
Echinococcus granulosus General substrate transporter 0.0091 0.1806 0.2386
Brugia malayi major facilitator superfamily protein 0.0015 0.0069 0.0129
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0527 0.0926
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0107 0.216 0.4393
Trypanosoma cruzi target of rapamycin kinase 3 0.0035 0.0516 0.2652
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0033 0.048 0.0414
Toxoplasma gondii lysine-tRNA ligase 0.0024 0.0268 0.0307
Leishmania major protein kinase, putative 0.0033 0.0479 0.2438
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0106 0.2146 0.2851
Brugia malayi MH2 domain containing protein 0.0247 0.5341 1
Echinococcus granulosus tumor protein p63 0.0336 0.7378 1
Echinococcus granulosus solute carrier family 22 0.0015 0.0069 0.0011
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0106 0.2146 0.2851
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0106 0.2146 0.2851
Echinococcus granulosus intermediate filament protein 0.003 0.0421 0.0493
Loa Loa (eye worm) hypothetical protein 0.0035 0.0527 0.0942
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0093 0.1849 0.583
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0069 0.0016
Onchocerca volvulus 0.0049 0.0848 0.155
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0043 0.0718 0.3825
Loa Loa (eye worm) hypothetical protein 0.0014 0.005 0.0045
Echinococcus granulosus solute carrier family 22 0.0015 0.0069 0.0011
Echinococcus granulosus lamin dm0 0.003 0.0421 0.0493
Loa Loa (eye worm) hypothetical protein 0.0035 0.0527 0.0942
Schistosoma mansoni glucose transporter 0.0015 0.0069 0.0027
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0069 0.0016
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0098 0.0219
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0032 0.0454 0.1098
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0037 0.0574 0.299
Echinococcus multilocularis dual specificity 0.009 0.1779 0.2349
Brugia malayi Calcitonin receptor-like protein seb-1 0.02 0.4282 0.8017
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0069 0.0016
Leishmania major glucose transporter, lmgt1 0.0033 0.0479 0.2433
Echinococcus granulosus beta LACTamase domain containing family member 0.0035 0.0527 0.0638
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0093 0.1849 0.2444
Schistosoma mansoni serine/threonine protein kinase 0.0033 0.0479 0.1366
Schistosoma mansoni hypothetical protein 0.0041 0.0652 0.1928
Echinococcus multilocularis musashi 0.003 0.0421 0.0493
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0063 0.1169 0.1516
Leishmania major glucose transporter/membrane transporter D2, putative 0.0033 0.0479 0.2433
Mycobacterium tuberculosis Conserved protein 0.0035 0.0527 0.0963
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0069 0.0016
Loa Loa (eye worm) hypothetical protein 0.0015 0.0069 0.0079
Brugia malayi beta-lactamase family protein 0.0035 0.0527 0.0986
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0021 0.0202 0.0281
Brugia malayi Major Facilitator Superfamily protein 0.0015 0.0069 0.0129
Schistosoma mansoni protein kinase 0.0033 0.0479 0.1366
Trypanosoma cruzi hexose transporter, putative 0.0033 0.0479 0.2433
Plasmodium vivax SET domain protein, putative 0.003 0.0405 0.0339
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0098 0.0219
Echinococcus multilocularis lamin 0.003 0.0421 0.0493
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0069 0.0016
Treponema pallidum NADH oxidase 0.0016 0.0098 0.5
Loa Loa (eye worm) hypothetical protein 0.0049 0.0848 0.1546
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0015 0.0063 0.0004
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0464 0.0802
Brugia malayi hypothetical protein 0.0015 0.0069 0.0129
Onchocerca volvulus 0.0035 0.0527 0.0911
Trypanosoma brucei THT1 - hexose transporter, putative 0.0033 0.0479 0.2433
Onchocerca volvulus 0.0035 0.0527 0.0911
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0037 0.0574 0.0778
Onchocerca volvulus 0.003 0.0421 0.0702
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0033 0.0479 0.0573
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.009 0.1779 1
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0069 0.0016
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0106 0.2146 0.2851
Echinococcus granulosus Niemann Pick C1 protein 0.014 0.2918 0.3905
Trichomonas vaginalis PIKK family atypical protein kinase 0.0023 0.0262 0.04
Trypanosoma brucei glucose transporter, putative 0.0033 0.0479 0.2433
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0069 0.0016
Entamoeba histolytica protein kinase, putative 0.0033 0.0479 0.1247
Toxoplasma gondii facilitative glucose transporter GT1 0.0106 0.2146 0.3196
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0035 0.0527 0.0963
Loa Loa (eye worm) hypothetical protein 0.0015 0.0069 0.0079
Plasmodium vivax hexose transporter 0.0106 0.2146 0.2092
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0033 0.048 0.0632
Brugia malayi Sugar transporter family protein 0.0015 0.0069 0.0129
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0035 0.0527 0.0963
Leishmania major glucose transporter, lmgt3 0.0033 0.0479 0.2433
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0069 0.0016
Echinococcus granulosus thioredoxin glutathione reductase 0.0047 0.0794 0.1003
Schistosoma mansoni lamin 0.003 0.0421 0.1177
Loa Loa (eye worm) hypothetical protein 0.0015 0.0069 0.0079
Schistosoma mansoni intermediate filament proteins 0.003 0.0421 0.1177
Loa Loa (eye worm) major facilitator superfamily transporter 0.0015 0.0069 0.0079
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0043 0.0718 0.3825
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0107 0.216 0.8791
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0033 0.0479 0.0573
Plasmodium falciparum calcium-dependent protein kinase 3 0.0033 0.048 0.0414
Echinococcus granulosus histone lysine methyltransferase setb 0.003 0.0405 0.0471
Brugia malayi beta-lactamase family protein 0.0035 0.0527 0.0986
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0106 0.2146 0.2851
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0093 0.1849 0.2444
Loa Loa (eye worm) glutathione reductase 0.0047 0.0794 0.1445
Loa Loa (eye worm) hypothetical protein 0.0015 0.0069 0.0079
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0032 0.0454 0.0538
Schistosoma mansoni hypothetical protein 0.0063 0.1169 0.3616
Brugia malayi MH1 domain containing protein 0.0017 0.0111 0.0208
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0069 0.0016
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0527 0.0926
Loa Loa (eye worm) sugar transporter 0.0015 0.0069 0.0079
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0464 0.0802
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.0718 0.1305
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0015 0.0063 0.0004
Mycobacterium tuberculosis Probable dehydrogenase 0.0107 0.216 0.4393
Echinococcus granulosus lamin 0.003 0.0421 0.0493
Trichomonas vaginalis PIKK family atypical protein kinase 0.0023 0.0262 0.04
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0043 0.0718 0.3825
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0033 0.0479 0.0573
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0069 0.0016
Schistosoma mansoni sugar transporter 0.0015 0.0069 0.0027
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0392 0.0659
Echinococcus granulosus Protein patched homolog 1 0.0042 0.0686 0.0855
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0172 0.3646 0.3602
Plasmodium falciparum calcium-dependent protein kinase 5 0.0033 0.048 0.0414
Schistosoma mansoni glucose transport protein 0.0106 0.2146 0.6801
Entamoeba histolytica hypothetical protein 0.009 0.1779 0.893
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.038 0.0437
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0069 0.0016
Onchocerca volvulus 0.0035 0.0527 0.0911
Trypanosoma brucei glucose transporter, putative 0.0033 0.0479 0.2433
Giardia lamblia Lysyl-tRNA synthetase 0.0024 0.0268 0.3077
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0405 0.0518
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0069 0.0016
Echinococcus granulosus synaptic vesicle 2 protein 0.0015 0.0069 0.0011
Echinococcus multilocularis tumor protein p63 0.0336 0.7378 1
Trypanosoma cruzi hexose transporter, putative 0.0033 0.0479 0.2433
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0016 0.0098 0.0051
Mycobacterium leprae conserved hypothetical protein 0.0035 0.0527 0.1515
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0107 0.216 0.4393
Loa Loa (eye worm) hypothetical protein 0.0015 0.0069 0.0079
Trypanosoma cruzi sugar transporter, putative 0.0015 0.0069 0.0048
Mycobacterium tuberculosis Conserved protein 0.0035 0.0527 0.0963
Loa Loa (eye worm) hypothetical protein 0.0015 0.0069 0.0079
Schistosoma mansoni hypothetical protein 0.0041 0.0652 0.1928
Brugia malayi Pre-SET motif family protein 0.003 0.0405 0.0759
Brugia malayi latrophilin 2 splice variant baaae 0.0137 0.2841 0.532
Trypanosoma brucei glucose transporter, putative 0.0033 0.0479 0.2433
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0119 0.2431 0.4963
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0093 0.1849 0.2444
Echinococcus multilocularis Smad4 0.0017 0.0111 0.0069
Trichomonas vaginalis sugar transporter, putative 0.0033 0.0479 0.083
Loa Loa (eye worm) hypothetical protein 0.0042 0.0686 0.1242
Brugia malayi hypothetical protein 0.0149 0.3122 0.5845
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0016 0.0098 0.0219
Trypanosoma cruzi trypanothione reductase, putative 0.0047 0.0794 0.4271
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0069 0.0016
Schistosoma mansoni hypothetical protein 0.0041 0.0652 0.1928
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0016 0.0098 0.0045
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0043 0.0718 0.1344
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0098 0.0219
Loa Loa (eye worm) hypothetical protein 0.0015 0.0069 0.0079
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.0098 0.0219
Loa Loa (eye worm) hypothetical protein 0.0035 0.0527 0.0942
Loa Loa (eye worm) major facilitator superfamily transporter 0.0015 0.0069 0.0079
Loa Loa (eye worm) Smad1 0.0017 0.0111 0.0159
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0032 0.0454 0.085
Brugia malayi Thioredoxin reductase 0.0047 0.0794 0.1487
Loa Loa (eye worm) hypothetical protein 0.0088 0.1722 0.3191
Loa Loa (eye worm) hypothetical protein 0.0024 0.0268 0.0455
Loa Loa (eye worm) hypothetical protein 0.0035 0.0527 0.0942
Echinococcus multilocularis thioredoxin glutathione reductase 0.0047 0.0794 0.1003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0023 0.0263 0.0402
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0024 0.0268 0.4358
Echinococcus multilocularis solute carrier family 22 0.0015 0.0069 0.0011
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0032 0.0454 0.085
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0106 0.2146 0.2851
Loa Loa (eye worm) hypothetical protein 0.0098 0.196 0.3638
Loa Loa (eye worm) hypothetical protein 0.0015 0.0069 0.0079
Toxoplasma gondii target of rapamycin (TOR), putative 0.0032 0.0464 0.0609
Loa Loa (eye worm) hypothetical protein 0.0137 0.2841 0.5296
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.0718 0.1305
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.009 0.1779 1
Trypanosoma cruzi glucose transporter, putative 0.0015 0.0069 0.0048
Trypanosoma brucei glucose transporter, putative 0.0033 0.0479 0.2433
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0464 0.0802
Schistosoma mansoni hypothetical protein 0.0137 0.2841 0.9067
Trichomonas vaginalis esterase, putative 0.0035 0.0527 0.0926
Schistosoma mansoni hypothetical protein 0.0063 0.1169 0.3616
Plasmodium falciparum glutathione reductase 0.0047 0.0794 0.0731
Schistosoma mansoni serine/threonine protein kinase 0.009 0.1779 0.5604
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0016 0.0098 0.0184
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0069 0.0016
Echinococcus multilocularis lamin dm0 0.003 0.0421 0.0493
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0069 0.0016
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0035 0.0516 0.2652
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.003 0.0405 0.1125
Echinococcus multilocularis calcium dependent protein kinase 0.0031 0.0423 0.0496
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.009 0.1779 1
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0063 0.1169 0.1516
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0098 0.0219
Schistosoma mansoni smad1 5 8 and 0.0017 0.0111 0.0165
Trypanosoma cruzi hexose transporter, putative 0.0033 0.0479 0.2433
Schistosoma mansoni niemann-pick C1 (NPC1) 0.01 0.1995 0.6307
Echinococcus granulosus lysyl tRNA synthetase 0.0024 0.0268 0.0284
Brugia malayi major facilitator superfamily protein 0.0015 0.0069 0.0129
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0033 0.0479 0.0573
Loa Loa (eye worm) MH2 domain-containing protein 0.0247 0.5341 1
Loa Loa (eye worm) hypothetical protein 0.0015 0.0069 0.0079
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0016 0.01 0.0138
Leishmania major lysyl-tRNA synthetase, putative 0.0024 0.0268 0.121
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0314 0.0503
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0037 0.0574 0.299
Loa Loa (eye worm) hypothetical protein 0.0035 0.0527 0.0942
Trichomonas vaginalis sugar transport protein, putative 0.0015 0.0069 0.0016
Brugia malayi MH2 domain containing protein 0.0017 0.0111 0.0208
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0069 0.0016
Loa Loa (eye worm) hypothetical protein 0.0052 0.0902 0.1647
Trypanosoma cruzi hexose transporter, putative 0.0018 0.0139 0.0455
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0224 0.4828 1
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0033 0.0479 0.0898
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0527 0.0926
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0069 0.0016
Trichomonas vaginalis conserved hypothetical protein 0.0106 0.2146 0.4141
Loa Loa (eye worm) MH2 domain-containing protein 0.0017 0.0111 0.0159
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0069 0.0016
Plasmodium falciparum calcium-dependent protein kinase 2 0.0033 0.048 0.0414
Toxoplasma gondii ABC1 family protein 0.0035 0.0527 0.0705
Mycobacterium tuberculosis Probable oxidoreductase 0.0119 0.2431 0.4963
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0515 0.0903

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.