Detailed information for compound 557797

Basic information

Technical information
  • TDR Targets ID: 557797
  • Name: allylbenzene
  • MW: 118.176 | Formula: C9H10
  • H donors: 0 H acceptors: 0 LogP: 2.99 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: C=CCc1ccccc1
  • InChi: 1S/C9H10/c1-2-6-9-7-4-3-5-8-9/h2-5,7-8H,1,6H2
  • InChiKey: HJWLCRVIBGQPNF-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • prop-2-enylbenzene
  • 300-57-2
  • 128961-80-8
  • 57807-91-7
  • 4-05-00-01362 (Beilstein Handbook Reference)
  • 1-Phenyl-2-propene
  • 1-Propene, 3-phenyl-
  • 2-Propenylbenzene
  • 3-Phenyl-1-propene
  • Benzene, 2-propenyl-
  • Benzene, allyl-
  • Benzene, propenyl-
  • NSC18609
  • WLN: 1U2R
  • InChI=1/C9H10/c1-2-6-9-7-4-3-5-8-9/h2-5,7-8H,1,6H
  • EINECS 206-095-7
  • BRN 1098501
  • ZINC01561526
  • NSC 18609
  • 05840_FLUKA
  • A29402_ALDRICH
  • 1-Benzylethene
  • 3-Phenylpropene

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.058 0.0842
Echinococcus granulosus protein C ets 2 0.0011 0.0026 0.0022
Schistosoma mansoni methyl-cpg binding protein mbd 0.0035 0.0297 0.0297
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0059 0.0522
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0016 0.0074 0.007
Wolbachia endosymbiont of Brugia malayi bacterioferritin/cytochrome b1 0.0009 0.0004 0.5
Schistosoma mansoni methyl-cpg binding protein mbd 0.0035 0.0297 0.0297
Trypanosoma cruzi ISWI complex protein 0.0032 0.0256 0.2145
Echinococcus granulosus GA binding protein alpha chain 0.0078 0.078 0.0776
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0101 0.1048 0.1044
Schistosoma mansoni kinase 0.0052 0.0483 0.0483
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.004 0.0348 0.0348
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.058 0.0842
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.004 0.0348 0.2041
Echinococcus multilocularis fetal alzheimer antigen, falz 0.005 0.0466 0.0462
Echinococcus multilocularis ETS transcription factor Elf 2 0.0011 0.0026 0.0022
Echinococcus granulosus ewsr:fli fusion protein type 0.0011 0.0026 0.0022
Schistosoma mansoni tsg101-related 0.0062 0.0603 0.0603
Toxoplasma gondii histone lysine methyltransferase SET1 0.0123 0.1297 1
Brugia malayi Fli-1 protein 0.0236 0.2575 0.3586
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.004 0.0348 0.0344
Echinococcus granulosus mixed lineage leukemia protein mll 0.0016 0.0074 0.007
Trichomonas vaginalis CAMK family protein kinase 0.0101 0.1048 1
Giardia lamblia Kinase, PLK 0.0101 0.1048 1
Loa Loa (eye worm) histone methyltransferase 0.0019 0.0118 0.0129
Schistosoma mansoni tsg101-related 0.0051 0.0474 0.0474
Loa Loa (eye worm) hypothetical protein 0.0037 0.0313 0.0403
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.006 0.058 0.0576
Schistosoma mansoni hypothetical protein 0.0182 0.1961 0.1961
Brugia malayi F/Y-rich N-terminus family protein 0.0023 0.016 0.0188
Treponema pallidum bacterioferrin (TpF1) 0.0009 0.0004 0.5
Trypanosoma brucei PAB1-binding protein , putative 0.0028 0.0214 0.1726
Entamoeba histolytica hypothetical protein 0.0039 0.0336 0.3031
Trypanosoma cruzi PAB1-binding protein , putative 0.0028 0.0214 0.1726
Loa Loa (eye worm) hypothetical protein 0.0075 0.0745 0.1011
Entamoeba histolytica hypothetical protein 0.0012 0.004 0.013
Plasmodium falciparum ataxin-2 like protein, putative 0.0028 0.0214 1
Loa Loa (eye worm) hypothetical protein 0.0324 0.3578 0.4996
Schistosoma mansoni hypothetical protein 0.0011 0.0026 0.0026
Trichomonas vaginalis CAMK family protein kinase 0.005 0.0468 0.4437
Schistosoma mansoni ferritin 0.0009 0.0004 0.0004
Trichomonas vaginalis CAMK family protein kinase 0.0101 0.1048 1
Schistosoma mansoni ets-related 0.0011 0.0026 0.0026
Echinococcus granulosus fetal alzheimer antigen falz 0.005 0.0466 0.0462
Schistosoma mansoni cpg binding protein 0.007 0.0693 0.0693
Trichomonas vaginalis helicase, putative 0.0014 0.0059 0.0522
Echinococcus multilocularis tumor susceptibility gene 101 protein 0.0075 0.0745 0.0741
Loa Loa (eye worm) hypothetical protein 0.0638 0.7135 1
Loa Loa (eye worm) MH2 domain-containing protein 0.0128 0.1352 0.1865
Brugia malayi hypothetical protein 0.0075 0.0745 0.1011
Echinococcus multilocularis ETS domain containing protein Elk 1 0.0011 0.0026 0.0022
Echinococcus multilocularis kelch ECH associated protein 1 0.0101 0.1048 0.1044
Echinococcus multilocularis dnaJ subfamily B 0.0891 1 1
Schistosoma mansoni gabp alpha 0.0078 0.078 0.078
Echinococcus granulosus ubiquitin specific protease 41 0.004 0.0348 0.0344
Loa Loa (eye worm) hypothetical protein 0.0146 0.1553 0.2148
Loa Loa (eye worm) hypothetical protein 0.0092 0.0937 0.1281
Echinococcus granulosus tar DNA binding protein 0.014 0.1485 0.1481
Loa Loa (eye worm) hypothetical protein 0.0084 0.0851 0.1161
Schistosoma mansoni tsg101-related 0.0062 0.0603 0.0603
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0059 0.0522
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0016 0.0074 0.007
Trichomonas vaginalis CAMK family protein kinase 0.005 0.0468 0.4437
Echinococcus multilocularis ETS transcription factor Elf 1 0.0011 0.0026 0.0022
Brugia malayi serine/threonine-protein kinase plk-2 0.0101 0.1048 0.1438
Brugia malayi Ets-domain containing protein 0.0078 0.078 0.106
Loa Loa (eye worm) hypothetical protein 0.0079 0.0796 0.1083
Entamoeba histolytica serine/threonine protein kinase, putative 0.0101 0.1048 1
Schistosoma mansoni tar DNA-binding protein 0.014 0.1485 0.1485
Brugia malayi hypothetical protein 0.0324 0.3578 0.4996
Schistosoma mansoni zinc finger protein 0.0044 0.0397 0.0397
Schistosoma mansoni ferritin 0.0009 0.0004 0.0004
Echinococcus multilocularis kelch ECH associated protein 1 0.0101 0.1048 0.1044
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0037 0.0313 0.0308
Schistosoma mansoni zinc finger protein 0.0032 0.0256 0.0256
Schistosoma mansoni hypothetical protein 0.0032 0.0256 0.0256
Brugia malayi RNA binding protein 0.014 0.1485 0.2052
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0059 0.0522
Loa Loa (eye worm) hypothetical protein 0.0066 0.0652 0.088
Mycobacterium leprae PROBABLE CONSERVED LIPOPROTEIN LPQF 0.0068 0.0674 0.098
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0014 0.0059 0.0522
Schistosoma mansoni hypothetical protein 0.0043 0.0381 0.0381
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0037 0.0313 0.0313
Schistosoma mansoni tar DNA-binding protein 0.014 0.1485 0.1485
Mycobacterium tuberculosis UDP-galactopyranose mutase Glf (UDP-GALP mutase) (NAD+-flavin adenine dinucleotide-requiring enzyme) 0.0611 0.6833 1
Echinococcus granulosus kelch ECH associated protein 1 like 0.0101 0.1048 0.1044
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.004 0.0348 0.306
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0127 0.1336 0.1332
Entamoeba histolytica hypothetical protein 0.0012 0.004 0.013
Echinococcus granulosus kelch ECH associated protein 1 like 0.0101 0.1048 0.1044
Loa Loa (eye worm) CXXC zinc finger family protein 0.0063 0.0608 0.0818
Trichomonas vaginalis CAMK family protein kinase 0.0101 0.1048 1
Trypanosoma cruzi ISWI complex protein 0.0032 0.0256 0.2145
Loa Loa (eye worm) PHD-finger family protein 0.0043 0.0381 0.0499
Echinococcus granulosus cpg binding protein 0.007 0.0693 0.0689
Brugia malayi hypothetical protein 0.0039 0.0336 0.0436
Schistosoma mansoni aldehyde dehydrogenase 0.006 0.058 0.058
Echinococcus multilocularis cpg binding protein 0.007 0.0693 0.0689
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.004 0.0348 0.0453
Trichomonas vaginalis CAMK family protein kinase 0.0101 0.1048 1
Onchocerca volvulus 0.0324 0.3578 1
Loa Loa (eye worm) TAR-binding protein 0.014 0.1485 0.2052
Loa Loa (eye worm) hypothetical protein 0.0638 0.7135 1
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0059 0.0522
Echinococcus multilocularis ETS transcription factor Elf 5 0.0011 0.0026 0.0022
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0014 0.0059 0.0522
Trichomonas vaginalis CAMK family protein kinase 0.0101 0.1048 1
Echinococcus granulosus ETS domain containing protein Elk 1 0.0011 0.0026 0.0022
Schistosoma mansoni tar DNA-binding protein 0.014 0.1485 0.1485
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0059 0.0522
Schistosoma mansoni polyomavirus enhancer activator 3 pea3 0.0011 0.0026 0.0026
Schistosoma mansoni cpg binding protein 0.007 0.0693 0.0693
Echinococcus multilocularis GA binding protein alpha chain 0.0078 0.078 0.0776
Entamoeba histolytica hypothetical protein 0.0012 0.004 0.013
Echinococcus multilocularis muscleblind protein 0.0638 0.7135 0.7133
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0014 0.0059 0.0522
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.005 0.0466 0.0466
Leishmania major hypothetical protein, conserved 0.0028 0.0214 0.0511
Schistosoma mansoni tar DNA-binding protein 0.014 0.1485 0.1485
Mycobacterium tuberculosis Probable conserved lipoprotein LpqF 0.0068 0.0674 0.098
Schistosoma mansoni myst-related protein 0.0011 0.0027 0.0027
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0035 0.0297 0.0293
Echinococcus granulosus methyl CpG binding domain protein 2 0.0035 0.0297 0.0293
Schistosoma mansoni bromodomain containing protein 0.0134 0.1419 0.1419
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.004 0.0348 0.0348
Loa Loa (eye worm) RNA binding protein 0.014 0.1485 0.2052
Echinococcus granulosus muscleblind protein 0.0638 0.7135 0.7133
Loa Loa (eye worm) transcription factor SMAD2 0.0128 0.1352 0.1865
Echinococcus granulosus histone lysine methyltransferase setb 0.0037 0.0313 0.0308
Trypanosoma brucei Vps23 core domain containing protein, putative 0.0024 0.0169 0.1281
Entamoeba histolytica hypothetical protein 0.0012 0.004 0.013
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0074 0.0739 0.0735
Trypanosoma brucei polo-like protein kinase 0.0101 0.1048 1
Echinococcus multilocularis ets variant gene 4 0.0011 0.0026 0.0022
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0059 0.0522
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.006 0.058 0.0842
Brugia malayi Bromodomain containing protein 0.0158 0.1694 0.2346
Schistosoma mansoni aldehyde dehydrogenase 0.006 0.058 0.058
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0014 0.0059 0.0522
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0059 0.0522
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.004 0.0348 0.306
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0059 0.0522
Plasmodium falciparum ataxin-2 like protein, putative 0.0028 0.0214 1
Mycobacterium tuberculosis Class a beta-lactamase BlaC 0.0142 0.1514 0.221
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.006 0.058 0.4671
Schistosoma mansoni apoferritin-2 0.0009 0.0004 0.0004
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.004 0.0348 0.315
Echinococcus granulosus kelch ECH associated protein 1 0.0101 0.1048 0.1044
Echinococcus granulosus geminin 0.0182 0.1961 0.1958
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.004 0.034
Brugia malayi CXXC zinc finger family protein 0.0063 0.0608 0.0818
Echinococcus granulosus ETS transcription factor Elf 5 0.0011 0.0026 0.0022
Entamoeba histolytica hypothetical protein 0.0039 0.0336 0.3031
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0101 0.1048 0.1044
Entamoeba histolytica tumor susceptibility gene 101 protein, putative 0.0051 0.0474 0.438
Loa Loa (eye worm) hypothetical protein 0.004 0.0348 0.0453
Schistosoma mansoni apoferritin-2 0.0009 0.0004 0.0004
Schistosoma mansoni hypothetical protein 0.0011 0.0026 0.0026
Schistosoma mansoni hypothetical protein 0.0039 0.0336 0.0336
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0014 0.0059 0.0522
Brugia malayi RNA recognition motif domain containing protein 0.014 0.1485 0.2052
Toxoplasma gondii aldehyde dehydrogenase 0.006 0.058 0.3376
Schistosoma mansoni ferritin light chain 0.0009 0.0004 0.0004
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.058 0.0842
Mycobacterium ulcerans class a beta-lactamase, BlaC 0.0142 0.1514 0.221
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.004 0.0348 0.3296
Echinococcus multilocularis Kelch repeat type 1 0.0102 0.1051 0.1047
Brugia malayi Muscleblind-like protein 0.0638 0.7135 1
Schistosoma mansoni ets 0.0011 0.0026 0.0026
Schistosoma mansoni elf1 0.0011 0.0026 0.0026
Echinococcus multilocularis muscleblind protein 1 0.0638 0.7135 0.7133
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0012 0.004 0.0035
Schistosoma mansoni hypothetical protein 0.0102 0.1051 0.1051
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.004 0.034
Trichomonas vaginalis hypothetical protein 0.0036 0.0311 0.2933
Schistosoma mansoni hypothetical protein 0.0891 1 1
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.004 0.0348 0.306
Brugia malayi Bromodomain containing protein 0.0079 0.0794 0.1081
Echinococcus granulosus zinc finger protein 0.0044 0.0397 0.0392
Mycobacterium leprae Probable UDP-galactopyranose mutase Glf (UDP-galp mutase) (NAD+-flavin adenine dinucleotide-requiring enzyme) 0.0611 0.6833 1
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0016 0.0074 0.007
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0019 0.0118 0.0113
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.004 0.0348 0.0344
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.004 0.0348 0.0344
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.006 0.058 0.0576
Entamoeba histolytica hypothetical protein 0.0039 0.0336 0.3031
Echinococcus multilocularis geminin 0.0182 0.1961 0.1958
Echinococcus multilocularis tar DNA binding protein 0.014 0.1485 0.1481
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0348 0.3296
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0074 0.0739 0.0735
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0014 0.0059 0.0522
Loa Loa (eye worm) bromodomain containing protein 0.0036 0.0312 0.0402
Loa Loa (eye worm) hypothetical protein 0.0012 0.0039 0.0018
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0014 0.0059 0.0522
Trypanosoma cruzi Vps23 core domain containing protein, putative 0.0024 0.0169 0.1281
Echinococcus multilocularis zinc finger protein 0.0044 0.0397 0.0392
Onchocerca volvulus Serine\/threonine kinase homolog 0.0101 0.1048 0.1484
Brugia malayi hypothetical protein 0.0018 0.0102 0.0107
Echinococcus multilocularis ewsr:fli fusion protein type 0.0011 0.0026 0.0022
Echinococcus granulosus ETS transcription factor Elf 2 0.0011 0.0026 0.0022
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0133 0.1403 0.1403
Entamoeba histolytica hypothetical protein 0.0039 0.0336 0.3031
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0012 0.004 0.0035
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0019 0.0118 0.0113
Brugia malayi Ets-domain containing protein 0.0078 0.078 0.106
Trypanosoma brucei ISWI complex protein 0.0032 0.0256 0.2145
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0127 0.1336 0.1332
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0059 0.0522
Loa Loa (eye worm) hypothetical protein 0.0028 0.0214 0.0264
Schistosoma mansoni cpg binding protein 0.0063 0.0608 0.0608
Brugia malayi TAR-binding protein 0.014 0.1485 0.2052
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.004 0.0348 0.0344
Trypanosoma brucei beta lactamase 0.0068 0.0674 0.6286
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0039 0.0336 0.0332
Trichomonas vaginalis CAMK family protein kinase 0.0101 0.1048 1
Schistosoma mansoni ets-related 0.0236 0.2575 0.2575
Mycobacterium ulcerans UDP-galactopyranose mutase Glf 0.0611 0.6833 1
Echinococcus granulosus tumor susceptibility gene 101 protein 0.0075 0.0745 0.0741
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0101 0.1048 0.1438
Schistosoma mansoni ferritin 0.0009 0.0004 0.0004
Schistosoma mansoni hypothetical protein 0.0012 0.004 0.004
Echinococcus multilocularis ETS transcription factor Elf 2 0.0011 0.0026 0.0022
Trypanosoma cruzi polo-like protein kinase, putative 0.0101 0.1048 1
Mycobacterium ulcerans lipoprotein LpqF 0.0068 0.0674 0.098
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0039 0.0336 0.0332
Schistosoma mansoni transcription factor LCR-F1 0.0039 0.0336 0.0336
Trichomonas vaginalis CAMK family protein kinase 0.0101 0.1048 1
Plasmodium vivax ataxin-2 like protein, putative 0.0028 0.0214 0.5
Schistosoma mansoni hypothetical protein 0.0182 0.1961 0.1961
Echinococcus multilocularis ubiquitin specific protease 41 0.004 0.0348 0.0344
Schistosoma mansoni ferritin 0.0009 0.0004 0.0004
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0016 0.0074 0.0074
Schistosoma mansoni bromodomain containing protein 0.0012 0.0039 0.0039
Schistosoma mansoni serine/threonine protein kinase 0.0101 0.1048 0.1048
Echinococcus granulosus ETS transcription factor Elf 2 0.0011 0.0026 0.0022
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.004 0.0348 0.3296
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0101 0.1048 1
Brugia malayi MH2 domain containing protein 0.0128 0.1352 0.1865
Schistosoma mansoni tar DNA-binding protein 0.014 0.1485 0.1485
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.014 0.1485 0.2052
Schistosoma mansoni myst-related protein 0.0011 0.0027 0.0027
Trypanosoma cruzi polo-like protein kinase, putative 0.0101 0.1048 1
Schistosoma mansoni ferritin light chain 0.0009 0.0004 0.0004
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0014 0.0059 0.0522
Brugia malayi PHD-finger family protein 0.0055 0.0522 0.0697
Brugia malayi hypothetical protein 0.0028 0.0214 0.0264
Loa Loa (eye worm) fli-1 protein 0.0236 0.2575 0.3586
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0037 0.0313 0.0313
Echinococcus granulosus ETS transcription factor Elf 1 0.0011 0.0026 0.0022
Leishmania major hypothetical protein, conserved 0.0032 0.0256 0.0992
Echinococcus multilocularis protein C ets 2 0.0011 0.0026 0.0022
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0078 0.078 0.106
Trypanosoma cruzi PAB1-binding protein , putative 0.0028 0.0214 0.1726

Activities

Activity type Activity value Assay description Source Reference
MIC (functional) = 400 ug ml-1 Antifungal activity against Saccharomyces cerevisiae ATCC 7754 after 2 days by broth dilution method ChEMBL. 8463795
MIC (functional) = 400 ug ml-1 Antifungal activity against Candida albicans ATCC 18804 after 2 days by broth dilution method ChEMBL. 8463795

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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