Detailed information for compound 559373

Basic information

Technical information
  • TDR Targets ID: 559373
  • Name: diethyl 2-[methoxy(methylsulfanyl)phosphoryl] sulfanylbutanedioate
  • MW: 330.358 | Formula: C10H19O6PS2
  • H donors: 0 H acceptors: 3 LogP: 0.82 Rotable bonds: 11
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCOC(=O)CC(C(=O)OCC)SP(=O)(SC)OC
  • InChi: 1S/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(13,14-3)18-4/h8H,5-7H2,1-4H3
  • InChiKey: LPQDGVLVYVULMX-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 2-[[methoxy-(methylthio)phosphoryl]thio]butanedioic acid diethyl ester
  • 2-[[methoxy-(methylthio)phosphoryl]thio]succinic acid diethyl ester
  • isomalathion
  • diethyl 2-(methoxy-methylsulfanylphosphoryl)sulfanylbutanedioate
  • diethyl 2-(methoxy-methylsulfanyl-phosphoryl)sulfanylbutanedioate
  • 3344-12-5
  • ((Methoxy(methylthio)phosphinyl)thio)butanedioic acid diethyl ester
  • (Methoxy(methylthio)phosphinothioyl)butanedioic acid diethyl ester
  • 8063HC
  • Butanedioic acid, ((methoxy(methylthio)phosphinothioyl)thio)diethyl ester (9CI)
  • CCRIS 5620
  • Mercaptosuccinic acid diethyl ester, S-ester with O,S-dimethylphosphorodithioate
  • S-Methylmalathion
  • Succinic acid, mercapto-, diethyl ester, S-ester with O,S-dimethyl phosphorodithioate
  • Butanedioic acid, ((methoxy(methylthio)phosphinothioyl)thio)diethyl ester

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi AMP-binding enzyme family protein 0.0023 0.015 0.0262
Leishmania major fructose-1,6-bisphosphate aldolase 0.0185 0.192 1
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0013 0.0037 0.0163
Trypanosoma cruzi fructose-bisphosphate aldolase, glycosomal, putative 0.0185 0.192 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0103 0.0507
Echinococcus multilocularis thyroid hormone receptor alpha 0.0013 0.0043 0.0007
Schistosoma mansoni hypothetical protein 0.0033 0.026 0.0592
Schistosoma mansoni retinoic acid receptor RXR 0.0013 0.0043 0.0016
Toxoplasma gondii histone lysine-specific demethylase 0.0065 0.0609 0.3152
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0087 0.0852 0.216
Brugia malayi hypothetical protein 0.0065 0.0609 0.1065
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0087 0.0852 0.096
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0022 0.0134 0.017
Schistosoma mansoni tar DNA-binding protein 0.0124 0.1258 0.3237
Brugia malayi nuclear hormone receptor 0.0013 0.0043 0.0075
Trichomonas vaginalis abcb9, putative 0.0022 0.0134 0.017
Trichomonas vaginalis ABC transporter, putative 0.0022 0.0134 0.017
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0031 0.0236 0.0527
Mycobacterium tuberculosis Probable oxidoreductase 0.0031 0.0236 0.0215
Brugia malayi photoreceptor-specific nuclear receptor 0.0013 0.0043 0.0075
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0013 0.0043 0.0075
Echinococcus multilocularis thioredoxin glutathione reductase 0.0037 0.0305 0.0316
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0013 0.0043 0.0075
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0013 0.0043 0.0016
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0013 0.0043 0.0075
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0013 0.0037 0.5
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0013 0.0043 0.0075
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0022 0.0134 0.017
Trypanosoma cruzi aldo-keto reductase 0.0031 0.0236 0.1202
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0031 0.0236 0.0234
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0022 0.0134 0.017
Schistosoma mansoni multidrug resistance protein 0.0022 0.0134 0.0256
Entamoeba histolytica P-glycoprotein-1 0.0022 0.0134 0.0055
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0022 0.0134 0.017
Echinococcus granulosus fructose 16 bisphosphate aldolase 0.0185 0.192 0.4992
Trichomonas vaginalis aldo/keto reductase, putative 0.0031 0.0236 0.035
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0531 0.5717 1
Loa Loa (eye worm) hypothetical protein 0.0017 0.0086 0.0076
Schistosoma mansoni nuclear hormone receptor 0.0013 0.0043 0.0016
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0013 0.0043 0.0016
Onchocerca volvulus 0.0031 0.0236 0.034
Mycobacterium ulcerans monoamine oxidase 0.0065 0.0609 0.0574
Schistosoma mansoni lipoxygenase 0.0357 0.3808 1
Entamoeba histolytica P-glycoprotein 5, putative 0.0022 0.0134 0.0055
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0022 0.0134 0.017
Brugia malayi AMP-binding enzyme family protein 0.0023 0.015 0.0262
Trypanosoma brucei prostaglandin f synthase 0.0031 0.0236 0.1202
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0084 0.0816 0.0842
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0013 0.0037 0.5
Plasmodium vivax lysine-specific histone demethylase 1, putative 0.0065 0.0609 0.3038
Mycobacterium tuberculosis Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) 0.0857 0.9289 1
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0022 0.0134 0.017
Trypanosoma brucei fructose-bisphosphate aldolase, glycosomal, putative 0.0185 0.192 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0103 0.0507
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0013 0.0043 0.0016
Schistosoma mansoni tar DNA-binding protein 0.0124 0.1258 0.3237
Trichomonas vaginalis aldo-keto reductase, putative 0.0031 0.0236 0.035
Onchocerca volvulus 0.0031 0.0236 0.034
Mycobacterium ulcerans phosphotyrosine protein phosphatase PtpA 0.0531 0.5717 0.5701
Echinococcus multilocularis aldo keto reductase 0.0031 0.0236 0.0234
Leishmania major ATP-binding cassette protein subfamily G, member 6, putative 0.0059 0.0546 0.2822
Trichomonas vaginalis aldo-keto reductase, putative 0.0031 0.0236 0.035
Loa Loa (eye worm) ATP-binding cassette sub-family B member 2 0.0022 0.0134 0.016
Brugia malayi steroid hormone receptor 0.0013 0.0043 0.0075
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0031 0.0236 0.0234
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0103 0.0507
Schistosoma mansoni terminal deoxycytidyl transferase 0.0019 0.0103 0.0175
Mycobacterium tuberculosis Probable oxidoreductase 0.0093 0.0918 0.0952
Echinococcus multilocularis ATP binding cassette sub family G 0.0059 0.0546 0.06
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0017 0.0086 0.0857
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0531 0.5717 1
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative 0.0531 0.5717 1
Onchocerca volvulus Netrin receptor homolog 0.0087 0.0852 0.1425
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0087 0.0852 0.216
Mycobacterium tuberculosis Conserved hypothetical protein 0.0065 0.0609 0.0618
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0022 0.0134 0.017
Brugia malayi amine oxidase, flavin-containing family protein 0.0065 0.0609 0.1065
Loa Loa (eye worm) fructose-bisphosphate aldolase 1 0.0185 0.192 0.3308
Echinococcus multilocularis multidrug resistance protein 1 0.0022 0.0134 0.0114
Loa Loa (eye worm) hypothetical protein 0.0065 0.0609 0.0998
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0031 0.0236 0.0234
Schistosoma mansoni coup transcription factor 0.0013 0.0043 0.0016
Trypanosoma brucei ABC transporter, putative 0.0059 0.0546 0.2822
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0031 0.0236 0.0527
Leishmania major trypanothione reductase 0.0037 0.03 0.1537
Echinococcus multilocularis fructose 1,6 bisphosphate aldolase 0.0185 0.192 0.2218
Schistosoma mansoni aldo-keto reductase 0.0031 0.0236 0.0527
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0013 0.0043 0.0075
Echinococcus granulosus ATP binding cassette sub family G 0.0059 0.0546 0.1349
Chlamydia trachomatis protoporphyrinogen oxidase 0.0065 0.0609 1
Trichomonas vaginalis aldo-keto reductase, putative 0.0031 0.0236 0.035
Echinococcus multilocularis RUN 0.006 0.0551 0.0606
Schistosoma mansoni hypothetical protein 0.0015 0.0065 0.0075
Schistosoma mansoni multidrug resistance protein 0.0022 0.0134 0.0256
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.015 0.0113
Schistosoma mansoni rab6-interacting 0.006 0.0551 0.1364
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0031 0.0236 0.0412
Trypanosoma cruzi trypanothione reductase, putative 0.0037 0.03 0.1537
Echinococcus multilocularis tar DNA binding protein 0.0124 0.1258 0.1438
Plasmodium vivax fructose 1,6-bisphosphate aldolase, putative 0.0185 0.192 1
Brugia malayi RNA binding protein 0.0124 0.1258 0.22
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0031 0.0236 0.0412
Schistosoma mansoni aldo-keto reductase 0.0031 0.0236 0.0527
Schistosoma mansoni cellular tumor antigen P53 0.0048 0.0424 0.1025
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0013 0.0043 0.0007
Echinococcus multilocularis protoporphyrinogen oxidase 0.0065 0.0609 0.0674
Loa Loa (eye worm) hypothetical protein 0.0017 0.0086 0.0076
Brugia malayi latrophilin 2 splice variant baaae 0.0033 0.026 0.0455
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0023 0.015 0.0122
Schistosoma mansoni lipoxygenase 0.025 0.2631 0.688
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0013 0.0043 0.0016
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0031 0.0236 0.0527
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative 0.0531 0.5717 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0013 0.0037 0.0163
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0031 0.0236 0.0234
Echinococcus granulosus fructose 16 bisphosphate aldolase 0.0185 0.192 0.4992
Leishmania major ATP-binding cassette protein subfamily B, member 2, putative 0.0022 0.0134 0.0668
Schistosoma mansoni RAR-like nuclear receptor 0.0013 0.0043 0.0016
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0922 1 1
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0022 0.0134 0.017
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0059 0.0546 0.0511
Loa Loa (eye worm) hypothetical protein 0.0019 0.0103 0.0106
Echinococcus granulosus multidrug resistance protein 1 0.0015 0.0065 0.0073
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0093 0.0918 1
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0022 0.0134 0.017
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0031 0.0236 0.0527
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0022 0.0134 0.017
Echinococcus multilocularis Polycystic kidney disease protein 0.006 0.0551 0.0606
Loa Loa (eye worm) hypothetical protein 0.0023 0.015 0.0188
Loa Loa (eye worm) oxidoreductase 0.0031 0.0236 0.034
Mycobacterium ulcerans oxidoreductase 0.0065 0.0609 0.0574
Onchocerca volvulus 0.0031 0.0236 0.034
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0013 0.0037 0.0163
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.034 0.3616 0.4217
Echinococcus granulosus Polycystic kidney disease protein 0.006 0.0551 0.1364
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0179 0.1854 0.3191
Brugia malayi RNA recognition motif domain containing protein 0.0124 0.1258 0.22
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0017 0.0086 0.0053
Brugia malayi Steroid receptor seven-up type 2 0.0013 0.0043 0.0075
Onchocerca volvulus 0.006 0.0551 0.0896
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0013 0.0043 0.0075
Entamoeba histolytica P-glycoprotein-5 0.0022 0.0134 0.0055
Plasmodium falciparum ABC transporter G family member 2 0.0059 0.0546 0.2703
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0013 0.0043 0.0075
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0103 0.0066
Echinococcus granulosus multidrug resistance protein 1 0.0022 0.0134 0.0256
Brugia malayi Nuclear hormone receptor-like 1 0.0013 0.0043 0.0075
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0023 0.015 0.0122
Schistosoma mansoni rab6-interacting 0.006 0.0551 0.1364
Echinococcus multilocularis GPCR, family 2 0.0015 0.0065 0.0033
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0013 0.0043 0.0007
Mycobacterium ulcerans oxidoreductase 0.0031 0.0236 0.0199
Brugia malayi Immunoglobulin I-set domain containing protein 0.0087 0.0852 0.149
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0103 0.0507
Loa Loa (eye worm) phosphotyrosine protein phosphatase 0.0531 0.5717 1
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0103 0.0507
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0022 0.0134 0.017
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0031 0.0236 0.0527
Entamoeba histolytica P-glycoprotein-2 0.0022 0.0134 0.0055
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative 0.0531 0.5717 1
Plasmodium falciparum protoporphyrinogen oxidase 0.0065 0.0609 0.3038
Trypanosoma brucei unspecified product 0.0013 0.0039 0.0174
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0013 0.0043 0.0016
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0013 0.0043 0.0016
Onchocerca volvulus 0.0031 0.0236 0.034
Trichomonas vaginalis aldo-keto reductase, putative 0.0031 0.0236 0.035
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0031 0.0236 0.0412
Echinococcus granulosus ATP binding cassette sub family G 0.0059 0.0546 0.1349
Toxoplasma gondii ATP-binding cassette G family transporter ABCG84 0.0059 0.0546 0.2822
Brugia malayi ecdysteroid receptor 0.0013 0.0043 0.0075
Echinococcus granulosus RUN 0.006 0.0551 0.1364
Plasmodium vivax hypothetical protein, conserved 0.0065 0.0609 0.3038
Leishmania major prostaglandin f synthase, putative 0.0031 0.0236 0.1202
Brugia malayi Death domain containing protein 0.0087 0.0852 0.149
Echinococcus multilocularis ATP binding cassette sub family G 0.0059 0.0546 0.06
Schistosoma mansoni amine oxidase 0.0065 0.0609 0.1517
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0023 0.015 0.0113
Schistosoma mansoni amine oxidase 0.0065 0.0609 0.1517
Loa Loa (eye worm) hypothetical protein 0.0023 0.015 0.0188
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0013 0.0043 0.0075
Brugia malayi Uncoordinated protein 44 0.0087 0.0852 0.149
Loa Loa (eye worm) protein-tyrosine phosphatase 0.034 0.3616 0.6297
Entamoeba histolytica acyl-coA synthetase, putative 0.0023 0.015 0.0084
Echinococcus granulosus tar DNA binding protein 0.0124 0.1258 0.3237
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0093 0.0918 0.0952
Echinococcus multilocularis aldehyde reductase 0.0022 0.0138 0.0119
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0022 0.0134 0.017
Onchocerca volvulus 0.0531 0.5717 1
Trypanosoma cruzi aldo/keto reductase, putative 0.0031 0.0236 0.1202
Trypanosoma cruzi ATP-binding cassette protein, putative 0.0059 0.0546 0.2822
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0103 0.0507
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0087 0.0852 0.1425
Echinococcus granulosus lipoxygenase domain containing protein 0.006 0.0551 0.1364
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0023 0.015 0.0113
Loa Loa (eye worm) hypothetical protein 0.0065 0.0609 0.0998
Echinococcus granulosus aldo keto reductase 0.0031 0.0236 0.0527
Trichomonas vaginalis ABC transporter, putative 0.0022 0.0134 0.017
Onchocerca volvulus 0.0048 0.0424 0.0671
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.015 0.0084
Plasmodium vivax protoporphyrinogen oxidase, putative 0.0065 0.0609 0.3038
Brugia malayi fructose-bisphosphate aldolase 2 0.0185 0.192 0.3358
Brugia malayi Protein kinase domain containing protein 0.0087 0.0852 0.149
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0019 0.0103 0.0116
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0015 0.0065 0.0033
Trypanosoma cruzi fructose-bisphosphate aldolase, glycosomal, putative 0.0185 0.192 1
Loa Loa (eye worm) hypothetical protein 0.0031 0.0236 0.034
Trichomonas vaginalis taga, putative 0.0022 0.0134 0.017
Echinococcus granulosus fructose bisphosphate aldolase class I 0.0185 0.192 0.4992
Schistosoma mansoni ankyrin 23/unc44 0.0087 0.0852 0.216
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0019 0.0103 0.0078
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0076 0.0042
Loa Loa (eye worm) thioredoxin reductase 0.0037 0.03 0.0453
Plasmodium falciparum LCCL domain-containing protein 0.006 0.0551 0.2732
Entamoeba histolytica P-glyco protein 6, putative 0.0022 0.0134 0.0055
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0048 0.0428 0.0748
Schistosoma mansoni thyroid hormone receptor 0.0013 0.0043 0.0016
Loa Loa (eye worm) multidrug resistance protein 3 0.0022 0.0134 0.016
Trichomonas vaginalis aldo-keto reductase, putative 0.0031 0.0236 0.035
Brugia malayi Doublecortin family protein 0.006 0.0551 0.0964
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0013 0.0043 0.0016
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0013 0.0043 0.0016
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0013 0.0037 0.0163
Brugia malayi Thioredoxin reductase 0.0037 0.03 0.0525
Giardia lamblia Low molecular weight protein-tyrosine-phosphatase 0.0531 0.5717 1
Loa Loa (eye worm) hypothetical protein 0.0021 0.0124 0.0142
Echinococcus granulosus ecdysone induced protein 78C 0.0013 0.0043 0.0016
Loa Loa (eye worm) hypothetical protein 0.006 0.0551 0.0896
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0013 0.0043 0.0075
Echinococcus multilocularis tumor protein p63 0.0328 0.3492 0.4071
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0124 0.1258 0.2141
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0031 0.0236 0.0234
Trichomonas vaginalis aldo-keto reductase, putative 0.0031 0.0236 0.035
Loa Loa (eye worm) oxidoreductase 0.0031 0.0236 0.034
Echinococcus granulosus lysine specific histone demethylase 1A 0.0065 0.0609 0.1517
Brugia malayi Protein-tyrosine phosphatase containing protein 0.034 0.3616 0.6325
Plasmodium falciparum acyl-CoA synthetase 0.0017 0.0086 0.026
Loa Loa (eye worm) RNA binding protein 0.0124 0.1258 0.2141
Echinococcus multilocularis ATP binding cassette sub family G 0.0059 0.0546 0.06
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.034 0.3616 0.9491
Schistosoma mansoni tumor necrosis factor receptor related 0.0133 0.1354 0.3492
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0022 0.0134 0.0114
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0013 0.0037 0.0163
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0022 0.0134 0.0256
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0084 0.0816 0.8687
Trypanosoma brucei aldo-keto reductase, putative 0.0031 0.0236 0.1202
Loa Loa (eye worm) hypothetical protein 0.0023 0.015 0.0188
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0013 0.0037 0.0163
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0103 0.0507
Echinococcus multilocularis multidrug resistance protein 1 0.0022 0.0134 0.0114
Onchocerca volvulus 0.0022 0.0134 0.016
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0531 0.5717 1
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0013 0.0043 0.0007
Trichomonas vaginalis aldo-keto reductase, putative 0.0031 0.0236 0.035
Brugia malayi Low molecular weight phosphotyrosine protein phosphatase containing protein 0.0531 0.5717 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0103 0.0507
Echinococcus multilocularis 0.0065 0.0609 0.0674
Loa Loa (eye worm) hypothetical protein 0.0065 0.0609 0.0998
Chlamydia trachomatis ABC transporter ATP binding protein/permease 0.0022 0.0134 0.1689
Brugia malayi ABC transporter family protein 0.0022 0.0134 0.0234
Echinococcus granulosus TNFR CD27 30 40 95 cysteine rich region 0.0133 0.1354 0.3492
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0103 0.0507
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0013 0.0043 0.0016
Toxoplasma gondii fructose-1,6-bisphosphate aldolase 0.0185 0.192 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0103 0.0507
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0103 0.018
Leishmania major p-glycoprotein 0.0022 0.0134 0.0668
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0103 0.0507
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0531 0.5717 1
Schistosoma mansoni tar DNA-binding protein 0.0124 0.1258 0.3237
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0.0039 0.0174
Schistosoma mansoni hypothetical protein 0.006 0.0551 0.1364
Treponema pallidum NADH oxidase 0.0013 0.0037 0.5
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0022 0.0134 0.0256
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0103 0.0066
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0076 0.0042
Brugia malayi Latrophilin receptor protein 2 0.0015 0.0065 0.0114
Schistosoma mansoni hypothetical protein 0.0015 0.0065 0.0075
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0037 0.03 0.0284
Echinococcus granulosus netrin receptor unc 5 0.0087 0.0852 0.216
Trichomonas vaginalis ABC transporter, putative 0.0022 0.0134 0.017
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0015 0.0065 0.0075
Schistosoma mansoni netrin receptor unc5 0.0087 0.0852 0.216
Echinococcus multilocularis dna polymerase kappa 0.0019 0.0103 0.0078
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.015 0.0753
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0022 0.0134 0.0114
Onchocerca volvulus 0.0031 0.0236 0.034
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0013 0.0043 0.0007
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0013 0.0043 0.0075
Schistosoma mansoni hypothetical protein 0.0015 0.0065 0.0075
Echinococcus multilocularis ecdysone induced protein 78C 0.0013 0.0043 0.0007
Echinococcus granulosus GPCR family 2 0.0015 0.0065 0.0075
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0013 0.0043 0.0075
Echinococcus multilocularis Ankyrin 0.0087 0.0852 0.096
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0103 0.0507
Echinococcus granulosus tumor necrosis factor receptor superfamily 0.0133 0.1354 0.3492
Schistosoma mansoni fructose 16-bisphosphate aldolase 0.0185 0.192 0.4992
Plasmodium vivax glutathione reductase, putative 0.0037 0.03 0.1397
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0788 0.8524 1
Echinococcus multilocularis aldo keto reductase 0.0031 0.0236 0.0234
Mycobacterium ulcerans hypothetical protein 0.0023 0.015 0.0113
Trichomonas vaginalis aldo-keto reductase, putative 0.0031 0.0236 0.035
Brugia malayi fructose-bisphosphate aldolase 1 0.0185 0.192 0.3358
Schistosoma mansoni fructose 16-bisphosphate aldolase 0.0185 0.192 0.4992
Leishmania major aldehyde reductase, putative,oxidoreductase, putative 0.0031 0.0236 0.1202
Echinococcus multilocularis aldo keto reductase 0.0031 0.0236 0.0234
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0084 0.0816 0.0842
Plasmodium falciparum lysine-specific histone demethylase 1, putative 0.0065 0.0609 0.3038
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0013 0.0037 0.0163
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.015 0.0113
Brugia malayi ABC transporter family protein 0.005 0.0448 0.0783
Echinococcus multilocularis TNFR CD27 30 40 95 cysteine rich region 0.0133 0.1354 0.1551
Loa Loa (eye worm) hypothetical protein 0.0179 0.1854 0.3191
Entamoeba histolytica P-glycoprotein-2, putative 0.0022 0.0134 0.0055
Schistosoma mansoni Protoporphyrinogen oxidase chloroplast/mitochondrial precursor 0.0065 0.0609 0.1517
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0013 0.0037 0.0163
Echinococcus multilocularis tumor necrosis factor receptor superfamily 0.0133 0.1354 0.1551
Schistosoma mansoni polycystin 1-related 0.006 0.0551 0.1364
Toxoplasma gondii NADPH-glutathione reductase 0.0013 0.0037 0.0163
Echinococcus granulosus dna polymerase kappa 0.0019 0.0103 0.0175
Onchocerca volvulus 0.0065 0.0609 0.0998
Plasmodium falciparum thioredoxin reductase 0.0037 0.03 0.1397
Loa Loa (eye worm) ABC transporter 0.005 0.0448 0.0714
Loa Loa (eye worm) TAR-binding protein 0.0124 0.1258 0.2141
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0031 0.0236 0.0527
Trypanosoma brucei unspecified product 0.0013 0.0039 0.0174
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0059 0.0546 0.0511
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0031 0.0236 0.035
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0013 0.0043 0.0075
Mycobacterium tuberculosis Conserved hypothetical protein 0.0019 0.0103 0.0071
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0013 0.0037 0.0163
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0013 0.0037 0.0163
Trichomonas vaginalis aldo-keto reductase, putative 0.0031 0.0236 0.035
Echinococcus granulosus death domain containing protein 0.0087 0.0852 0.216
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0013 0.0037 0.0163
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.015 0.0084
Mycobacterium tuberculosis Phosphotyrosine protein phosphatase PtpA (protein-tyrosine-phosphatase) (PTPase) (LMW phosphatase) 0.0531 0.5717 0.6139
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0022 0.0134 0.0114
Plasmodium falciparum multidrug resistance protein 1 0.0022 0.0134 0.0513
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0022 0.0134 0.017
Schistosoma mansoni thyroid hormone receptor 0.0013 0.0043 0.0016
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0.0039 0.0174
Loa Loa (eye worm) hypothetical protein 0.0048 0.0424 0.0671
Echinococcus granulosus dna polymerase eta 0.0019 0.0103 0.0175
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0084 0.0816 0.0842
Entamoeba histolytica ABC transporter, putative 0.0059 0.0546 0.0789
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0022 0.0134 0.017
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0022 0.0134 0.0256
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0013 0.0037 0.0163
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0357 0.3808 0.4443
Loa Loa (eye worm) hypothetical protein 0.0017 0.0086 0.0076
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0103 0.0507
Plasmodium vivax ABC transporter G family member 2, putative 0.0059 0.0546 0.2703
Leishmania major ATP-binding cassette protein subfamily G, member 4, putative 0.0059 0.0546 0.2822
Brugia malayi AMP-binding enzyme family protein 0.0023 0.015 0.0262
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0013 0.0043 0.0016
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0031 0.0236 0.0234
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0015 0.0065 0.0033
Loa Loa (eye worm) latrophilin receptor protein 2 0.0015 0.0065 0.004
Giardia lamblia DINP protein human, muc B family 0.0019 0.0103 0.0116
Brugia malayi nuclear receptor NHR-88 0.0013 0.0043 0.0075
Trypanosoma cruzi ABC transporter, putative 0.0059 0.0546 0.2822
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0013 0.0043 0.0007
Schistosoma mansoni hypothetical protein 0.0087 0.0852 0.216
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0022 0.0134 0.0114
Loa Loa (eye worm) glutathione reductase 0.0037 0.03 0.0453
Giardia lamblia Aldose reductase 0.0031 0.0236 0.035
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0031 0.0236 0.0527
Giardia lamblia ABC transporter 0.0058 0.0536 0.0878
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0019 0.0103 0.0175
Brugia malayi multidrug resistance protein 3 0.0022 0.0134 0.0234
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0015 0.0065 0.0114
Schistosoma mansoni protein tyrosine phosphatase non-receptor type nt1 0.034 0.3616 0.9491
Schistosoma mansoni ATP-binding cassette sub-family g2 (white protein) (abcg2) 0.0059 0.0546 0.1349
Leishmania major UDP-galactopyranose mutase 0.0065 0.0609 0.3152
Echinococcus multilocularis multidrug resistance protein 1 0.0015 0.0065 0.0033
Schistosoma mansoni tar DNA-binding protein 0.0124 0.1258 0.3237
Entamoeba histolytica aldose reductase, putative 0.0031 0.0236 0.0237
Loa Loa (eye worm) hypothetical protein 0.0048 0.0428 0.0679
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.015 0.0753
Loa Loa (eye worm) oxidoreductase 0.0031 0.0236 0.034
Echinococcus granulosus lysine specific histone demethylase 1A 0.0065 0.0609 0.1517
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0.0039 0.0174
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0022 0.0134 0.0668
Echinococcus multilocularis FTZ F1 alpha 0.0013 0.0043 0.0007
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0031 0.0236 0.0234
Echinococcus multilocularis lysine specific histone demethylase 1A 0.0065 0.0609 0.0674
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0013 0.0037 0.0163
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0022 0.0134 0.017
Echinococcus granulosus Ankyrin 0.0087 0.0852 0.216
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0013 0.0037 0.0163
Toxoplasma gondii fructose-bisphosphate aldolase, putative 0.0185 0.192 1
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0031 0.0236 0.0234
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0019 0.0103 0.0507
Echinococcus multilocularis ATP binding cassette sub family B 0.0021 0.0124 0.0102
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0013 0.0037 0.0163
Plasmodium vivax thioredoxin reductase, putative 0.0037 0.03 0.1397
Loa Loa (eye worm) hypothetical protein 0.0033 0.026 0.0383
Echinococcus granulosus lipoxygenase domain containing protein 0.006 0.0551 0.1364
Echinococcus granulosus fructose 16 bisphosphate aldolase 0.0185 0.192 0.4992
Schistosoma mansoni hypothetical protein 0.0049 0.0438 0.1062
Toxoplasma gondii histone lysine-specific demethylase LSD1/BHC110/KDMA1A 0.0065 0.0609 0.3152
Entamoeba histolytica P-glycoprotein-2 0.0022 0.0134 0.0055
Trypanosoma cruzi trypanothione reductase, putative 0.0013 0.0037 0.0163
Mycobacterium tuberculosis Possible oxidoreductase 0.0065 0.0609 0.0618
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0065 0.0609 0.3038
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0013 0.0043 0.0016
Trichomonas vaginalis aldo-keto reductase, putative 0.0031 0.0236 0.035
Echinococcus granulosus aldo keto reductase 0.0031 0.0236 0.0527
Toxoplasma gondii thioredoxin reductase 0.0037 0.03 0.1537
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0013 0.0043 0.0016
Leishmania major prostaglandin f2-alpha synthase/D-arabinose dehydrogenase 0.0031 0.0236 0.1202
Brugia malayi SWIRM domain containing protein 0.0065 0.0609 0.1065
Mycobacterium tuberculosis Probable reductase 0.0084 0.0816 0.0842
Trypanosoma brucei DNA polymerase eta, putative 0.0019 0.0103 0.0507
Mycobacterium tuberculosis Probable dehydrogenase 0.0084 0.0816 0.0842
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0022 0.0134 0.017
Loa Loa (eye worm) hypothetical protein 0.0022 0.0134 0.016
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.015 0.0753
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0022 0.0134 0.017
Echinococcus granulosus multidrug resistance protein 1 0.0022 0.0134 0.0256
Leishmania major DNA polymerase kappa, putative 0.0019 0.0103 0.0507
Echinococcus multilocularis lipoxygenase domain containing protein 0.006 0.0551 0.0606
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0013 0.0043 0.0075
Trichomonas vaginalis aldo-keto reductase, putative 0.0031 0.0236 0.035
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0059 0.0546 0.0511
Trypanosoma cruzi fructose-bisphosphate aldolase, glycosomal, putative 0.0185 0.192 1
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0048 0.0428 0.0679
Loa Loa (eye worm) hypothetical protein 0.0087 0.0852 0.1425
Loa Loa (eye worm) hypothetical protein 0.0022 0.0134 0.016
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0103 0.0507
Loa Loa (eye worm) hypothetical protein 0.0065 0.0609 0.0998
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0103 0.018
Mycobacterium tuberculosis Probable conserved transmembrane ATP-binding protein ABC transporter 0.0049 0.0438 0.0433
Leishmania major aldo-keto reductase-like protein 0.0031 0.0236 0.1202
Echinococcus multilocularis dna polymerase eta 0.0019 0.0103 0.0078
Loa Loa (eye worm) hypothetical protein 0.0065 0.0609 0.0998
Trypanosoma brucei ATP-binding cassette protein, putative 0.0059 0.0546 0.2822
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0022 0.0134 0.017
Echinococcus granulosus aldehyde reductase 0.0022 0.0138 0.0267
Echinococcus multilocularis fructose 1,6 bisphosphate aldolase 0.0185 0.192 0.2218
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0103 0.0507
Brugia malayi hypothetical protein 0.006 0.0551 0.0964
Brugia malayi hypothetical protein 0.006 0.0551 0.0964
Echinococcus granulosus multidrug resistance protein 1 0.0015 0.0065 0.0073
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0023 0.015 0.0113
Trypanosoma brucei trypanothione reductase 0.0037 0.03 0.1537
Trypanosoma brucei unspecified product 0.0019 0.0103 0.0507
Mycobacterium tuberculosis Probable transmembrane multidrug efflux pump 0.0022 0.0134 0.0104
Onchocerca volvulus 0.0031 0.0236 0.034
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0022 0.0134 0.017
Toxoplasma gondii aldose reductase, putative 0.0031 0.0236 0.1202
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0013 0.0043 0.0016
Schistosoma mansoni ABC transporter 0.005 0.0448 0.1089
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0076 0.0042
Brugia malayi Calcitonin receptor-like protein seb-1 0.0048 0.0428 0.0748
Entamoeba histolytica aldose reductase, putative 0.0031 0.0236 0.0237
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0023 0.015 0.0153
Onchocerca volvulus 0.006 0.0551 0.0896
Trichomonas vaginalis DNA polymerase eta, putative 0.0019 0.0103 0.0116
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0015 0.0065 0.0049
Trichomonas vaginalis ABC transporter, putative 0.0022 0.0134 0.017
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0019 0.0103 0.0175
Schistosoma mansoni multidrug resistance protein 0.0022 0.0134 0.0256
Trichomonas vaginalis aldo-keto reductase, putative 0.0031 0.0236 0.035
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0103 0.0507
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0019 0.0103 0.0071
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0031 0.0236 0.0234
Mycobacterium leprae PROBABLE PROTOPORPHYRINOGEN OXIDASE HEMY (PROTOPORPHYRINOGEN-IX OXIDASE) (PROTOPORPHYRINOGENASE) (PPO) 0.0065 0.0609 0.604
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0031 0.0236 0.0527
Plasmodium vivax hypothetical protein, conserved 0.0065 0.0609 0.3038
Echinococcus multilocularis fructose 1,6 bisphosphate aldolase 0.0185 0.192 0.2218
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0084 0.0816 0.0842
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0093 0.0918 0.0952
Toxoplasma gondii fructose-1,6-bisphosphate aldolase 0.0185 0.192 1
Echinococcus multilocularis fructose bisphosphate aldolase class I 0.0185 0.192 0.2218
Loa Loa (eye worm) hypothetical protein 0.0065 0.0609 0.0998
Trichomonas vaginalis abcb9, putative 0.0022 0.0134 0.017
Loa Loa (eye worm) oxidoreductase 0.0031 0.0236 0.034
Loa Loa (eye worm) hypothetical protein 0.0015 0.0065 0.004
Echinococcus granulosus aldo keto reductase 0.0031 0.0236 0.0527
Plasmodium falciparum fructose-bisphosphate aldolase 0.0185 0.192 1
Schistosoma mansoni hypothetical protein 0.0015 0.0065 0.0075
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0023 0.015 0.0153
Echinococcus granulosus multidrug resistance protein 1 0.0022 0.0134 0.0256
Echinococcus granulosus 5'partial|ATP binding cassette sub family B 0.0021 0.0124 0.023
Trichomonas vaginalis aldo/keto reductase, putative 0.0031 0.0236 0.035
Trichomonas vaginalis aldo/keto reductase, putative 0.0031 0.0236 0.035
Mycobacterium leprae PROBABLE OXIDOREDUCTASE 0.0031 0.0236 0.1256
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0031 0.0236 0.0527
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0015 0.0065 0.0075
Loa Loa (eye worm) hypothetical protein 0.0087 0.0852 0.1425
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0022 0.0134 0.017
Plasmodium vivax acyl-CoA synthetase, putative 0.0017 0.0086 0.026
Trypanosoma cruzi UDP-galactopyranose mutase 0.0065 0.0609 0.3152
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0013 0.0037 0.0065
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.015 0.0113
Loa Loa (eye worm) fructose-bisphosphate aldolase 2 0.0185 0.192 0.3308
Loa Loa (eye worm) hypothetical protein 0.0017 0.0086 0.0076
Brugia malayi N-terminal motif family protein 0.0179 0.1854 0.3243
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0031 0.0236 0.0234
Plasmodium vivax multidomain scavenger receptor, putative 0.006 0.0551 0.2732
Loa Loa (eye worm) hypothetical protein 0.006 0.0551 0.0896
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0019 0.0103 0.0106
Echinococcus multilocularis aldo keto reductase 0.0031 0.0236 0.0234
Plasmodium falciparum glutathione reductase 0.0037 0.03 0.1397
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0022 0.0134 0.0114
Brugia malayi TAR-binding protein 0.0124 0.1258 0.22
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0031 0.0236 0.0412
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0031 0.0236 0.035
Echinococcus granulosus FTZ F1 alpha 0.0013 0.0043 0.0016
Schistosoma mansoni loxhd1 0.006 0.0551 0.1364
Echinococcus multilocularis netrin receptor unc 5 0.0087 0.0852 0.096
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0017 0.0086 0.0049
Schistosoma mansoni tar DNA-binding protein 0.0124 0.1258 0.3237
Leishmania major DNA polymerase eta, putative 0.0019 0.0103 0.0507
Trypanosoma cruzi UDP-galactopyranose mutase 0.0065 0.0609 0.3152
Giardia lamblia Aldose reductase 0.0031 0.0236 0.035
Schistosoma mansoni pol-related 0.0031 0.0236 0.0527
Echinococcus granulosus tumor protein p63 0.0328 0.3492 0.9163
Schistosoma mansoni Lysine-specific histone demethylase 1 0.0065 0.0609 0.1517
Echinococcus granulosus thioredoxin glutathione reductase 0.0037 0.0305 0.0712
Schistosoma mansoni steroid hormone receptor ad4bp 0.0013 0.0043 0.0016
Mycobacterium ulcerans dehydrogenase 0.0065 0.0609 0.0574
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0076 0.0042
Brugia malayi glutathione reductase 0.0037 0.03 0.0525
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0031 0.0236 0.035
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0357 0.3808 1
Trypanosoma cruzi fructose-bisphosphate aldolase, glycosomal, putative 0.0185 0.192 1
Toxoplasma gondii ATP-binding cassette transporter ABC.B1 0.0022 0.0134 0.0668
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0013 0.0043 0.0007
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0023 0.015 0.0113
Entamoeba histolytica aldose reductase, putative 0.0031 0.0236 0.0237
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0022 0.0134 0.0256
Loa Loa (eye worm) doublecortin family protein 0.006 0.0551 0.0896
Echinococcus granulosus ATP binding cassette sub family G 0.0059 0.0546 0.1349
Onchocerca volvulus 0.0023 0.015 0.0188
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0022 0.0134 0.017
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0022 0.0134 0.017
Echinococcus granulosus hypothetical protein 0.0031 0.0236 0.0527
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0031 0.0236 0.0234
Schistosoma mansoni smdr2 0.0022 0.0134 0.0256
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0013 0.0037 0.0163
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0103 0.0507
Schistosoma mansoni DNA polymerase eta 0.0019 0.0103 0.0175
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0013 0.0037 0.0163
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0531 0.5717 1
Trichomonas vaginalis abcb9, putative 0.0022 0.0134 0.017
Mycobacterium ulcerans protoporphyrinogen oxidase 0.0065 0.0609 0.0574
Plasmodium vivax multidrug resistance protein 1, putative 0.0022 0.0134 0.0513
Trypanosoma cruzi DNA polymerase eta, putative 0.0019 0.0103 0.0507
Loa Loa (eye worm) hypothetical protein 0.0017 0.0086 0.0076
Echinococcus multilocularis lipoxygenase domain containing protein 0.006 0.0551 0.0606
Loa Loa (eye worm) oxidoreductase 0.0031 0.0236 0.034

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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