Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | 0.0459 | 0.1302 | 0.116 | |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0262 | 0.0539 | 0.0577 |
Loa Loa (eye worm) | hypothetical protein | 0.0262 | 0.0539 | 0.0539 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0376 | 0.0979 | 0.8104 |
Loa Loa (eye worm) | Sodium:neurotransmitter symporter family protein | 0.0459 | 0.1302 | 0.1302 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0376 | 0.0979 | 1 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0376 | 0.0979 | 0.1814 |
Schistosoma mansoni | sodium/chloride dependent transporter | 0.0459 | 0.1302 | 0.1302 |
Loa Loa (eye worm) | hypothetical protein | 0.0459 | 0.1302 | 0.1302 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0376 | 0.0979 | 0.8104 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0376 | 0.0979 | 0.8104 |
Schistosoma mansoni | sodium-dependent neurotransmitter transporter | 0.0459 | 0.1302 | 0.1302 |
Schistosoma mansoni | sodium-dependent amino acid transporter | 0.0459 | 0.1302 | 0.1302 |
Plasmodium vivax | hypothetical protein, conserved | 0.0459 | 0.1302 | 1 |
Echinococcus multilocularis | purine nucleoside phosphorylase | 0.0308 | 0.0715 | 0.0694 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0376 | 0.0979 | 0.8104 |
Echinococcus granulosus | purine nucleoside phosphorylase | 0.0308 | 0.0715 | 0.0694 |
Plasmodium falciparum | eukaryotic initiation factor 4A | 0.0261 | 0.0533 | 0.2067 |
Loa Loa (eye worm) | hypothetical protein | 0.0262 | 0.0539 | 0.0539 |
Echinococcus granulosus | purine nucleoside phosphorylase | 0.0308 | 0.0715 | 0.0694 |
Echinococcus granulosus | sodium:chloride dependent neurotransmitter | 0.0459 | 0.1302 | 0.1283 |
Onchocerca volvulus | 0.0376 | 0.0979 | 0.0832 | |
Onchocerca volvulus | 0.0459 | 0.1302 | 0.116 | |
Loa Loa (eye worm) | hypothetical protein | 0.0164 | 0.016 | 0.016 |
Brugia malayi | Sodium:neurotransmitter symporter family protein | 0.0459 | 0.1302 | 0.1302 |
Toxoplasma gondii | hypothetical protein | 0.0459 | 0.1302 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0376 | 0.0979 | 0.8104 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0209 | 0.0333 | 0.0333 |
Leishmania major | cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like | 0.0415 | 0.113 | 1 |
Trypanosoma cruzi | Eukaryotic initiation factor 4A-1 | 0.0261 | 0.0533 | 0.0562 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0209 | 0.0333 | 0.0333 |
Onchocerca volvulus | 0.0376 | 0.0979 | 0.0832 | |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0376 | 0.0979 | 0.8104 |
Loa Loa (eye worm) | hypothetical protein | 0.0244 | 0.0468 | 0.0468 |
Onchocerca volvulus | Eukaryotic initiation factor 4A homolog | 0.0261 | 0.0533 | 0.0379 |
Loa Loa (eye worm) | hypothetical protein | 0.0459 | 0.1302 | 0.1302 |
Toxoplasma gondii | hypothetical protein | 0.0459 | 0.1302 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0376 | 0.0979 | 0.8104 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.1128 | 0.3892 | 0.3892 |
Toxoplasma gondii | Sodium:neurotransmitter symporter family protein | 0.0459 | 0.1302 | 1 |
Brugia malayi | Sodium:neurotransmitter symporter family protein 1, putative | 0.0459 | 0.1302 | 0.1302 |
Onchocerca volvulus | 0.0376 | 0.0979 | 0.0832 | |
Loa Loa (eye worm) | Sodium:neurotransmitter symporter family protein | 0.0459 | 0.1302 | 0.1302 |
Entamoeba histolytica | DEAD/DEAH box helicase, putative | 0.0261 | 0.0533 | 0.3101 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0376 | 0.0979 | 0.8104 |
Echinococcus multilocularis | purine nucleoside phosphorylase | 0.0308 | 0.0715 | 0.0694 |
Plasmodium falciparum | amino acid transporter, putative | 0.0459 | 0.1302 | 1 |
Schistosoma mansoni | norepinephrine/norepinephrine transporter | 0.0459 | 0.1302 | 0.1302 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0376 | 0.0979 | 0.8104 |
Echinococcus multilocularis | eukaryotic initiation factor 4A | 0.0261 | 0.0533 | 0.0513 |
Mycobacterium ulcerans | purine nucleoside phosphorylase | 0.0308 | 0.0715 | 0.5 |
Onchocerca volvulus | 0.0376 | 0.0979 | 0.0832 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0376 | 0.0979 | 0.8104 |
Schistosoma mansoni | DEAD box ATP-dependent RNA helicase | 0.0261 | 0.0533 | 0.0533 |
Echinococcus granulosus | eukaryotic initiation factor 4A III | 0.0261 | 0.0533 | 0.0513 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0376 | 0.0979 | 0.0979 |
Trypanosoma brucei | Eukaryotic initiation factor 4A-1 | 0.0261 | 0.0533 | 0.2513 |
Plasmodium vivax | amine transporter, putative | 0.0459 | 0.1302 | 1 |
Schistosoma mansoni | purine nucleoside phosphorylase | 0.0308 | 0.0715 | 0.0715 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.1128 | 0.3892 | 0.3892 |
Loa Loa (eye worm) | hypothetical protein | 0.0164 | 0.016 | 0.016 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0376 | 0.0979 | 0.1814 |
Onchocerca volvulus | 0.0376 | 0.0979 | 0.0832 | |
Onchocerca volvulus | Purine nucleoside phosphorylase homolog | 0.0308 | 0.0715 | 0.0563 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0376 | 0.0979 | 0.6665 |
Mycobacterium leprae | Probable purine nucleoside phosphorylase DeoD (INOSINE PHOSPHORYLASE) (PNP) | 0.0308 | 0.0715 | 0.5 |
Brugia malayi | Cathepsin L-like precursor | 0.0376 | 0.0979 | 0.0979 |
Brugia malayi | Cathepsin L-like precursor | 0.0376 | 0.0979 | 0.0979 |
Schistosoma mansoni | sodium/chloride dependent transporter | 0.2705 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0376 | 0.0979 | 0.0979 |
Loa Loa (eye worm) | solute carrier family 6 member 4 | 0.2705 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0465 | 0.1324 | 0.1324 |
Onchocerca volvulus | Cathepsin F homolog | 0.0376 | 0.0979 | 0.0832 |
Plasmodium vivax | vivapain-2 | 0.0376 | 0.0979 | 0.6665 |
Schistosoma mansoni | sodium-dependent neurotransmitter transporter | 0.0459 | 0.1302 | 0.1302 |
Schistosoma mansoni | sodium/chloride dependent transporter | 0.0459 | 0.1302 | 0.1302 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0376 | 0.0979 | 0.0959 |
Loa Loa (eye worm) | ctsf protein | 0.0376 | 0.0979 | 0.0979 |
Brugia malayi | purine nucleoside phosphorylase I, inosine and guanosine-specific family protein | 0.0308 | 0.0715 | 0.0715 |
Echinococcus multilocularis | cathepsin b | 0.1128 | 0.3892 | 0.3879 |
Entamoeba histolytica | cysteine protease, putative | 0.0376 | 0.0979 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0209 | 0.0333 | 0.0333 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0376 | 0.0979 | 0.8104 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0376 | 0.0979 | 0.8104 |
Echinococcus granulosus | cysteine protease | 0.0209 | 0.0333 | 0.0312 |
Loa Loa (eye worm) | hypothetical protein | 0.1128 | 0.3892 | 0.3892 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0376 | 0.0979 | 0.8104 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0376 | 0.0979 | 0.8104 |
Brugia malayi | Cathepsin L-like precursor | 0.0262 | 0.0539 | 0.0539 |
Echinococcus multilocularis | purine nucleoside phosphorylase | 0.0308 | 0.0715 | 0.0694 |
Echinococcus multilocularis | eukaryotic initiation factor 4A III | 0.0261 | 0.0533 | 0.0513 |
Loa Loa (eye worm) | hypothetical protein | 0.0261 | 0.0533 | 0.0533 |
Toxoplasma gondii | cathepsin B | 0.0415 | 0.113 | 0.7762 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0376 | 0.0979 | 0.1814 |
Trichomonas vaginalis | purine nucleoside phosphorylase I, putative | 0.0308 | 0.0715 | 0.4788 |
Schistosoma mansoni | norepinephrine/norepinephrine transporter | 0.2705 | 1 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.0415 | 0.113 | 1 |
Loa Loa (eye worm) | DEAH box polypeptide 35 | 0.0465 | 0.1324 | 0.1324 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0262 | 0.0539 | 0.0539 |
Onchocerca volvulus | 0.2705 | 1 | 1 | |
Giardia lamblia | Cathepsin B precursor | 0.0415 | 0.113 | 1 |
Brugia malayi | Sodium:neurotransmitter symporter family protein | 0.0459 | 0.1302 | 0.1302 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0376 | 0.0979 | 0.0959 |
Schistosoma mansoni | family C2 unassigned peptidase (C02 family) | 0.0129 | 0.0022 | 0.0022 |
Trichomonas vaginalis | DEAD box ATP-dependent RNA helicase, putative | 0.0261 | 0.0533 | 0.2513 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0376 | 0.0979 | 0.8104 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0376 | 0.0979 | 0.1814 |
Loa Loa (eye worm) | hypothetical protein | 0.0459 | 0.1302 | 0.1302 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0376 | 0.0979 | 0.8104 |
Echinococcus granulosus | uncharacterized sodium dependent transporter | 0.0459 | 0.1302 | 0.1283 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0262 | 0.0539 | 0.3182 |
Leishmania major | cathepsin L-like protease | 0.0376 | 0.0979 | 0.7468 |
Onchocerca volvulus | Cathepsin L homolog | 0.0376 | 0.0979 | 0.0832 |
Schistosoma mansoni | sodium/chloride dependent neurotransmitter transporter | 0.0459 | 0.1302 | 0.1302 |
Echinococcus multilocularis | sodium and chloride dependent glycine | 0.0459 | 0.1302 | 0.1283 |
Echinococcus granulosus | purine nucleoside phosphorylase | 0.0308 | 0.0715 | 0.0694 |
Echinococcus granulosus | purine nucleoside phosphorylase | 0.0308 | 0.0715 | 0.0694 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0376 | 0.0979 | 0.8104 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0376 | 0.0979 | 0.0979 |
Plasmodium vivax | vivapain-2 | 0.0376 | 0.0979 | 0.6665 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0376 | 0.0979 | 0.8104 |
Echinococcus granulosus | purine nucleoside phosphorylase | 0.0308 | 0.0715 | 0.0694 |
Leishmania major | cathepsin L-like protease | 0.0376 | 0.0979 | 0.7468 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0376 | 0.0979 | 0.8104 |
Echinococcus granulosus | cathepsin b | 0.1128 | 0.3892 | 0.3879 |
Schistosoma mansoni | DEAD box ATP-dependent RNA helicase | 0.0261 | 0.0533 | 0.0533 |
Loa Loa (eye worm) | hypothetical protein | 0.0459 | 0.1302 | 0.1302 |
Plasmodium vivax | RNA helicase-1, putative | 0.0261 | 0.0533 | 0.2067 |
Echinococcus multilocularis | cysteine protease | 0.0376 | 0.0979 | 0.0959 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0376 | 0.0979 | 0.6665 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0376 | 0.0979 | 0.8104 |
Echinococcus granulosus | cathepsin L | 0.0209 | 0.0333 | 0.0312 |
Leishmania major | cathepsin L-like protease | 0.0376 | 0.0979 | 0.7468 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0376 | 0.0979 | 0.8104 |
Loa Loa (eye worm) | cysteine protease | 0.0376 | 0.0979 | 0.0979 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.1128 | 0.3892 | 0.3892 |
Onchocerca volvulus | 0.0376 | 0.0979 | 0.0832 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0415 | 0.113 | 1 |
Trichomonas vaginalis | DEAD box ATP-dependent RNA helicase, putative | 0.0261 | 0.0533 | 0.2513 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0376 | 0.0979 | 0.8104 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0262 | 0.0539 | 0.0539 |
Brugia malayi | Sodium:neurotransmitter symporter family protein | 0.0459 | 0.1302 | 0.1302 |
Leishmania major | cathepsin L-like protease | 0.0376 | 0.0979 | 0.7468 |
Echinococcus granulosus | cathepsin l1 | 0.0376 | 0.0979 | 0.0959 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0376 | 0.0979 | 0.0959 |
Echinococcus granulosus | uncharacterized sodium dependent transporter | 0.0459 | 0.1302 | 0.1283 |
Loa Loa (eye worm) | hypothetical protein | 0.0376 | 0.0979 | 0.0979 |
Brugia malayi | Cathepsin L-like precursor | 0.0376 | 0.0979 | 0.0979 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0376 | 0.0979 | 0.0979 |
Giardia lamblia | Purine nucleoside phosphorylase lateral transfer candidate | 0.0308 | 0.0715 | 0.3038 |
Treponema pallidum | sodium- and chloride- dependent transporter | 0.2705 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0376 | 0.0979 | 0.8104 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0262 | 0.0539 | 0.2579 |
Giardia lamblia | Cathepsin B precursor | 0.0415 | 0.113 | 1 |
Echinococcus granulosus | cathepsin b | 0.1128 | 0.3892 | 0.3879 |
Mycobacterium tuberculosis | Probable purine nucleoside phosphorylase DeoD (inosine phosphorylase) (PNP) | 0.0308 | 0.0715 | 1 |
Echinococcus multilocularis | purine nucleoside phosphorylase | 0.0308 | 0.0715 | 0.0694 |
Loa Loa (eye worm) | hypothetical protein | 0.0459 | 0.1302 | 0.1302 |
Schistosoma mansoni | sodium/chloride dependent neurotransmitter transporter | 0.0459 | 0.1302 | 0.1302 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0376 | 0.0979 | 0.8104 |
Loa Loa (eye worm) | hypothetical protein | 0.2705 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0376 | 0.0979 | 0.0979 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0415 | 0.113 | 0.113 |
Loa Loa (eye worm) | cathepsin B | 0.0415 | 0.113 | 0.113 |
Echinococcus granulosus | sodium and chloride dependent glycine | 0.0459 | 0.1302 | 0.1283 |
Onchocerca volvulus | Cathepsin L homolog | 0.0376 | 0.0979 | 0.0832 |
Echinococcus multilocularis | sodium and chloride dependent glycine | 0.0459 | 0.1302 | 0.1283 |
Echinococcus granulosus | inosine guanosine and xanthosine phosphorylase | 0.0244 | 0.0468 | 0.0447 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0376 | 0.0979 | 0.6665 |
Onchocerca volvulus | 0.0262 | 0.0539 | 0.0384 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0262 | 0.0539 | 0.2579 |
Loa Loa (eye worm) | hypothetical protein | 0.0459 | 0.1302 | 0.1302 |
Onchocerca volvulus | 0.0376 | 0.0979 | 0.0832 | |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0376 | 0.0979 | 0.8104 |
Loa Loa (eye worm) | hypothetical protein | 0.2705 | 1 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0376 | 0.0979 | 0.0959 |
Echinococcus multilocularis | cathepsin L | 0.0209 | 0.0333 | 0.0312 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0376 | 0.0979 | 0.8104 |
Brugia malayi | Probable ATP-dependent helicase DHX35 | 0.0465 | 0.1324 | 0.1324 |
Schistosoma mansoni | sodium-dependent neurotransmitter transporter | 0.0459 | 0.1302 | 0.1302 |
Leishmania major | cathepsin L-like protease | 0.0376 | 0.0979 | 0.7468 |
Brugia malayi | Trypsin family protein | 0.0164 | 0.016 | 0.016 |
Chlamydia trachomatis | Ssodium-dependent amino acid transporter | 0.0459 | 0.1302 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0376 | 0.0979 | 0.8104 |
Echinococcus multilocularis | cathepsin b | 0.1128 | 0.3892 | 0.3879 |
Leishmania major | cathepsin L-like protease | 0.0376 | 0.0979 | 0.7468 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.1128 | 0.3892 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0376 | 0.0979 | 0.8104 |
Onchocerca volvulus | 0.0459 | 0.1302 | 0.116 | |
Leishmania major | cathepsin L-like protease | 0.0376 | 0.0979 | 0.7468 |
Echinococcus granulosus | cathepsin l1 | 0.0262 | 0.0539 | 0.0518 |
Brugia malayi | Cathepsin L-like precursor | 0.0262 | 0.0539 | 0.0539 |
Echinococcus multilocularis | serotonin transporter | 0.2705 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0376 | 0.0979 | 0.8104 |
Leishmania major | cathepsin L-like protease | 0.0376 | 0.0979 | 0.7468 |
Echinococcus granulosus | serotonin transporter | 0.2705 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0376 | 0.0979 | 0.1814 |
Leishmania major | cysteine peptidase A (CPA) | 0.0376 | 0.0979 | 0.7468 |
Echinococcus multilocularis | uncharacterized sodium dependent transporter | 0.0459 | 0.1302 | 0.1283 |
Echinococcus multilocularis | purine nucleoside phosphorylase | 0.0244 | 0.0468 | 0.0447 |
Echinococcus granulosus | eukaryotic initiation factor 4A | 0.0261 | 0.0533 | 0.0513 |
Loa Loa (eye worm) | hypothetical protein | 0.2705 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0376 | 0.0979 | 0.8104 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0376 | 0.0979 | 0.0959 |
Echinococcus granulosus | cathepsin L cysteine protease | 0.0209 | 0.0333 | 0.0312 |
Echinococcus granulosus | purine nucleoside phosphorylase | 0.0308 | 0.0715 | 0.0694 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0376 | 0.0979 | 0.8104 |
Trypanosoma cruzi | Eukaryotic initiation factor 4A-1 | 0.0261 | 0.0533 | 0.0562 |
Loa Loa (eye worm) | fibroinase | 0.0376 | 0.0979 | 0.0979 |
Echinococcus multilocularis | sodium:chloride dependent neurotransmitter | 0.0459 | 0.1302 | 0.1283 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0164 | 0.016 | 0.016 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0209 | 0.0333 | 0.0333 |
Toxoplasma gondii | cathepsin CPL | 0.0376 | 0.0979 | 0.5797 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.1128 | 0.3892 | 0.3892 |
Toxoplasma gondii | Sodium:neurotransmitter symporter family protein | 0.0459 | 0.1302 | 1 |
Echinococcus multilocularis | cysteine protease | 0.0376 | 0.0979 | 0.0959 |
Echinococcus multilocularis | sodium dependent neurotransmitter transporter | 0.0459 | 0.1302 | 0.1283 |
Brugia malayi | Cathepsin L-like precursor | 0.0376 | 0.0979 | 0.0979 |
Trichomonas vaginalis | DEAD box ATP-dependent RNA helicase, putative | 0.0261 | 0.0533 | 0.2513 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0376 | 0.0979 | 0.0979 |
Loa Loa (eye worm) | norepinephrine transporter | 0.2705 | 1 | 1 |
Toxoplasma gondii | Sodium:neurotransmitter symporter family protein | 0.0459 | 0.1302 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0376 | 0.0979 | 0.8104 |
Echinococcus granulosus | purine nucleoside phosphorylase | 0.0308 | 0.0715 | 0.0694 |
Brugia malayi | cathepsin L-like precursor | 0.0262 | 0.0539 | 0.0539 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0376 | 0.0979 | 1 |
Echinococcus granulosus | sodium and chloride dependent glycine | 0.0459 | 0.1302 | 0.1283 |
Echinococcus granulosus | purine nucleoside phosphorylase | 0.0308 | 0.0715 | 0.0694 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0164 | 0.016 | 0.016 |
Loa Loa (eye worm) | serotonin transporter b | 0.2705 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0376 | 0.0979 | 0.8104 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.0415 | 0.113 | 1 |
Echinococcus multilocularis | purine nucleoside phosphorylase | 0.0308 | 0.0715 | 0.0694 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0376 | 0.0979 | 0.8104 |
Loa Loa (eye worm) | hypothetical protein | 0.0459 | 0.1302 | 0.1302 |
Echinococcus multilocularis | purine nucleoside phosphorylase | 0.0244 | 0.0468 | 0.0447 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0376 | 0.0979 | 0.0959 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0376 | 0.0979 | 0.8104 |
Plasmodium falciparum | transporter, putative | 0.0459 | 0.1302 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0262 | 0.0539 | 0.0539 |
Brugia malayi | cathepsin B-like cysteine proteinase | 0.1128 | 0.3892 | 0.3892 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0376 | 0.0979 | 0.0979 |
Schistosoma mansoni | sodium/chloride dependent neurotransmitter transporter | 0.0459 | 0.1302 | 0.1302 |
Echinococcus multilocularis | purine nucleoside phosphorylase | 0.0308 | 0.0715 | 0.0694 |
Brugia malayi | eukaryotic initiation factor 4A | 0.0261 | 0.0533 | 0.0533 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0415 | 0.113 | 0.2238 |
Schistosoma mansoni | family C2 unassigned peptidase (C02 family) | 0.0129 | 0.0022 | 0.0022 |
Brugia malayi | hypothetical protein | 0.0459 | 0.1302 | 0.1302 |
Schistosoma mansoni | norepinephrine/norepinephrine transporter | 0.0459 | 0.1302 | 0.1302 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0209 | 0.0333 | 0.0333 |
Echinococcus granulosus | sodium dependent neurotransmitter transporter | 0.0459 | 0.1302 | 0.1283 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0376 | 0.0979 | 0.8104 |
Schistosoma mansoni | purine nucleoside phosphorylase | 0.0308 | 0.0715 | 0.0715 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
K6 (binding) | = 0.013 s-1 | Rate constant of compound was determined for interaction with human purine nucleoside phosphorylase(PNP) | ChEMBL. | 12502369 |
K6 (binding) | = 0.021 s-1 | Rate constant of compound was determined for interaction with bovine purine nucleoside phosphorylase(PNP) | ChEMBL. | 12502369 |
Ki (binding) | = 42 pM | Inhibitory activity of compound against bovine purine nucleoside phosphorylase(PNP) | ChEMBL. | 12502369 |
Ki (binding) | = 104 pM | Inhibitory activity of compound against human purine nucleoside phosphorylase(PNP) | ChEMBL. | 12502369 |
Ki (binding) | = 1.6 uM | Inhibitory activity of compound against inosine-uridine nucleoside hydrolase (IU-NH) from crithidia fasciculata | ChEMBL. | 12502369 |
Ki (binding) | = 13.9 uM | Inhibitory activity of compound against perine-specific inosine-adenosine-guanosine nucleoside hydrolase (IAG-NH) from trypanosoma brucei | ChEMBL. | 12502369 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.