Detailed information for compound 630631

Basic information

Technical information
  • TDR Targets ID: 630631
  • Name: 1-[4-(2-ethoxyphenyl)piperazin-1-yl]-3-(4-met hylphenyl)prop-2-en-1-one
  • MW: 350.454 | Formula: C22H26N2O2
  • H donors: 0 H acceptors: 1 LogP: 4.1 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCOc1ccccc1N1CCN(CC1)C(=O)C=Cc1ccc(cc1)C
  • InChi: 1S/C22H26N2O2/c1-3-26-21-7-5-4-6-20(21)23-14-16-24(17-15-23)22(25)13-12-19-10-8-18(2)9-11-19/h4-13H,3,14-17H2,1-2H3/b13-12+
  • InChiKey: KXHXGFBVZQTPOS-OUKQBFOZSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • (E)-1-[4-(2-ethoxyphenyl)piperazin-1-yl]-3-(4-methylphenyl)prop-2-en-1-one
  • 1-[4-(2-ethoxyphenyl)-1-piperazinyl]-3-(4-methylphenyl)prop-2-en-1-one
  • (E)-1-[4-(2-ethoxyphenyl)-1-piperazinyl]-3-(4-methylphenyl)prop-2-en-1-one
  • ZINC01200644

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Onchocerca volvulus 0.01 0.0927 1
Leishmania major protein kinase, putative 0.0059 0.0494 0.4978
Schistosoma mansoni sex comb on midleg homolog 0.0048 0.038 0.038
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0051 0.0418 0.5056
Brugia malayi Probable ClpP-like protease 0.0078 0.0703 0.0703
Schistosoma mansoni serine/threonine protein kinase 0.0059 0.0494 0.0494
Echinococcus granulosus polycomb protein SCMH1 0.0048 0.038 0.038
Loa Loa (eye worm) MBCTL1 0.0054 0.045 0.045
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0024 0.0126 0.0991
Plasmodium falciparum ataxin-2 like protein, putative 0.003 0.0189 0.1975
Echinococcus multilocularis protein dispatched 1 0.0048 0.0386 0.0386
Schistosoma mansoni pten 0.0095 0.0882 0.0882
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0078 0.0703 1
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0126 0.0991
Echinococcus multilocularis cyclin g associated kinase 0.0959 1 1
Brugia malayi Fibronectin type III domain containing protein 0.0047 0.0367 0.0367
Trichomonas vaginalis CMGC family protein kinase 0.0059 0.0494 0.4978
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0024 0.0126 0.0991
Echinococcus granulosus dual specificity protein kinase clk2 0.0059 0.0494 0.0494
Trypanosoma cruzi PAB1-binding protein , putative 0.003 0.0189 0.1031
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0054 0.045 0.045
Schistosoma mansoni sex comb on midleg homolog 0.0048 0.038 0.038
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0048 0.038 0.4102
Loa Loa (eye worm) hypothetical protein 0.0047 0.0367 0.0367
Entamoeba histolytica acyl-coA synthetase, putative 0.0024 0.0126 0.0207
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0126 0.0991
Loa Loa (eye worm) hypothetical protein 0.0018 0.0063 0.0063
Schistosoma mansoni patched 1 0.0042 0.0322 0.0322
Echinococcus granulosus hypothetical protein 0.0054 0.0443 0.0443
Leishmania major protein kinase, putative 0.0059 0.0494 0.4978
Loa Loa (eye worm) hypothetical protein 0.0095 0.0882 0.0882
Entamoeba histolytica hypothetical protein 0.0036 0.0256 0.1814
Plasmodium vivax serine/threonine kinase-1, putative 0.0059 0.0494 0.5265
Toxoplasma gondii LsmAD domain-containing protein 0.003 0.0189 0.1343
Trichomonas vaginalis pten, drome, putative 0.0095 0.0882 1
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0046 0.0359 0.0359
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0013 0.0016 0.0016
Schistosoma mansoni niemann-pick C1 (NPC1) 0.01 0.0933 0.0933
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0042 0.0322 0.0322
Schistosoma mansoni hypothetical protein 0.0036 0.0256 0.0256
Brugia malayi Niemann-Pick C1 protein precursor 0.0099 0.0917 0.0917
Loa Loa (eye worm) hypothetical protein 0.0042 0.0322 0.0322
Echinococcus multilocularis Niemann Pick C1 protein 0.0141 0.1364 0.1364
Loa Loa (eye worm) hypothetical protein 0.0048 0.038 0.038
Echinococcus granulosus peptidase Clp S14 family 0.0051 0.0418 0.0418
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0078 0.0703 0.0703
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0027 0.0161 0.0593
Schistosoma mansoni peptidase Clp (S14 family) 0.0078 0.0703 0.0703
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0027 0.0161 0.0858
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0046 0.0359 0.0359
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0024 0.0126 0.0991
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0126 0.0216
Loa Loa (eye worm) hypothetical protein 0.0054 0.0443 0.0443
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0022 0.011 0.073
Echinococcus granulosus cyclin g associated kinase 0.0959 1 1
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0046 0.0359 0.0359
Loa Loa (eye worm) hypothetical protein 0.0488 0.503 0.503
Loa Loa (eye worm) hypothetical protein 0.0024 0.0126 0.0126
Leishmania major tyrosine phosphatase isoform, putative 0.0095 0.0882 1
Schistosoma mansoni hypothetical protein 0.0041 0.0306 0.0306
Echinococcus multilocularis expressed conserved protein 0.0093 0.0854 0.0854
Schistosoma mansoni hypothetical protein 0.0295 0.299 0.299
Loa Loa (eye worm) hypothetical protein 0.0047 0.0367 0.0367
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0812 0.8454 0.8454
Brugia malayi Immunoglobulin I-set domain containing protein 0.0047 0.0367 0.0367
Loa Loa (eye worm) hypothetical protein 0.0018 0.0063 0.0063
Brugia malayi hypothetical protein 0.0019 0.0078 0.0078
Echinococcus granulosus Immunoglobulin 0.0047 0.0367 0.0367
Schistosoma mansoni serine/threonine protein kinase 0.0959 1 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0359 0.0359
Echinococcus granulosus roundabout 2 0.0058 0.0491 0.0491
Echinococcus granulosus defective proboscis extension response 0.0047 0.0367 0.0367
Schistosoma mansoni myelin transcription factor 1 myt1 0.0054 0.045 0.045
Echinococcus multilocularis survival motor neuron protein 1 0.0488 0.503 0.503
Echinococcus granulosus survival motor neuron protein 1 0.0488 0.503 0.503
Schistosoma mansoni transcription factor LCR-F1 0.0036 0.0256 0.0256
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0126 0.0207
Loa Loa (eye worm) hypothetical protein 0.0058 0.0491 0.0491
Brugia malayi hypothetical protein 0.0036 0.0256 0.0256
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0126 0.0216
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0054 0.045 0.045
Loa Loa (eye worm) hypothetical protein 0.003 0.0189 0.0189
Echinococcus multilocularis peptidase Clp (S14 family) 0.0051 0.0418 0.0418
Entamoeba histolytica phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase, putative 0.0095 0.0882 0.9569
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0126 0.0126
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0058 0.0489 0.0489
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0046 0.0359 0.0359
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0027 0.0161 0.1526
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0024 0.0126 0.2017
Toxoplasma gondii hypothetical protein 0.0027 0.0161 0.0858
Schistosoma mansoni tyrosine kinase 0.0017 0.0058 0.0058
Onchocerca volvulus 0.0024 0.0126 0.1363
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0322 0.2755
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0078 0.0703 1
Brugia malayi Protein kinase domain containing protein 0.0059 0.0494 0.0494
Schistosoma mansoni hypothetical protein 0.0041 0.0306 0.0306
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0022 0.011 0.011
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0193 0.1911 0.1911
Echinococcus granulosus Niemann Pick C1 protein 0.0099 0.0917 0.0917
Brugia malayi exodeoxyribonuclease III family protein 0.0022 0.011 0.011
Echinococcus granulosus Protein patched homolog 1 0.0042 0.0322 0.0322
Schistosoma mansoni atypical protein kinase C 0.0014 0.0022 0.0022
Giardia lamblia Kinase, CMGC CLK 0.0059 0.0494 1
Mycobacterium ulcerans hypothetical protein 0.0024 0.0126 0.0991
Loa Loa (eye worm) hypothetical protein 0.0047 0.0367 0.0367
Loa Loa (eye worm) hypothetical protein 0.0099 0.0917 0.0917
Brugia malayi hypothetical protein 0.003 0.0189 0.0189
Trypanosoma brucei PAB1-binding protein , putative 0.003 0.0189 0.2071
Echinococcus granulosus SAM and MBT domain containing protein 0.0048 0.038 0.038
Echinococcus multilocularis Niemann Pick C1 protein 0.0099 0.0917 0.0917
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0046 0.0359 0.0359
Schistosoma mansoni cell adhesion molecule 0.0053 0.0431 0.0431
Trypanosoma cruzi tyrosine phosphatase, putative 0.0095 0.0882 1
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0018 0.0063 0.028
Schistosoma mansoni nephrin 0.0052 0.0427 0.0427
Loa Loa (eye worm) hypothetical protein 0.0024 0.0126 0.0126
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0046 0.0359 0.0359
Echinococcus multilocularis SAM and MBT domain containing protein 0.0048 0.038 0.038
Echinococcus multilocularis Immunoglobulin 0.0047 0.0367 0.0367
Loa Loa (eye worm) hypothetical protein 0.0058 0.0491 0.0491
Loa Loa (eye worm) hypothetical protein 0.0052 0.0423 0.0423
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0126 0.0126
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0126 0.0216
Trypanosoma cruzi tyrosine phosphatase isoform, putative 0.0095 0.0882 1
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0126 0.0126
Entamoeba histolytica hypothetical protein 0.0036 0.0256 0.1814
Plasmodium falciparum ataxin-2 like protein, putative 0.003 0.0189 0.1975
Brugia malayi Protein kinase domain containing protein 0.0014 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0047 0.0367 0.0367
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0047 0.0367 0.0367
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0078 0.0703 1
Trypanosoma cruzi PAB1-binding protein , putative 0.003 0.0189 0.1031
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0022 0.011 0.073
Schistosoma mansoni vesicular amine transporter 0.0047 0.0367 0.0367
Brugia malayi daf-18 protein 0.0095 0.0882 0.0882
Brugia malayi Immunoglobulin I-set domain containing protein 0.0058 0.0489 0.0489
Brugia malayi hypothetical protein 0.0047 0.0367 0.0367
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0059 0.0494 0.4978
Brugia malayi mbt repeat family protein 0.0048 0.038 0.038
Brugia malayi mbt repeat family protein 0.0048 0.038 0.038
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0078 0.0703 0.0703
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0051 0.0418 1
Echinococcus multilocularis protein patched 0.0042 0.0322 0.0322
Loa Loa (eye worm) hypothetical protein 0.0078 0.0703 0.0703
Plasmodium vivax formin 2, putative 0.0095 0.0882 1
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0051 0.0418 1
Echinococcus granulosus histone acetyltransferase MYST2 0.0054 0.045 0.045
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0126 0.0207
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0078 0.0703 1
Loa Loa (eye worm) hypothetical protein 0.0018 0.0063 0.0063
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0013 0.0016 0.0016
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0022 0.011 0.057
Brugia malayi CHE-14 protein 0.0042 0.0322 0.0322
Echinococcus multilocularis phosphatase and tensin 0.0095 0.0882 0.0882
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0048 0.038 0.038
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0036 0.0256 0.0256
Entamoeba histolytica hypothetical protein 0.0036 0.0256 0.1814
Onchocerca volvulus 0.0048 0.038 0.4102
Echinococcus multilocularis Immunoglobulin 0.0047 0.0367 0.0367
Loa Loa (eye worm) mbt repeat family protein 0.0048 0.038 0.038
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.01 0.0927 0.0927
Echinococcus granulosus Niemann Pick C1 protein 0.0141 0.1364 0.1364
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0022 0.011 0.011
Plasmodium falciparum protein serine/threonine kinase-1 0.0059 0.0494 0.6741
Schistosoma mansoni hypothetical protein 0.0041 0.0306 0.0306
Loa Loa (eye worm) hypothetical protein 0.0024 0.0126 0.0126
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0024 0.0126 0.2017
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0054 0.045 0.045
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0078 0.0703 0.781
Schistosoma mansoni hypothetical protein 0.0041 0.0306 0.0306
Loa Loa (eye worm) hypothetical protein 0.0053 0.0431 0.0431
Echinococcus multilocularis roundabout 2 0.0058 0.0491 0.0491
Schistosoma mansoni survival motor neuron protein 0.01 0.0927 0.0927
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0022 0.011 0.011
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0059 0.0494 0.4978
Loa Loa (eye worm) hypothetical protein 0.0018 0.0063 0.0063
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0053 0.0431 0.0431
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0078 0.0703 1
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0036 0.0256 0.0256
Loa Loa (eye worm) hypothetical protein 0.0054 0.045 0.045
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0022 0.011 0.156
Loa Loa (eye worm) NAK/GAK protein kinase 0.0959 1 1
Echinococcus granulosus neuroglian 0.0052 0.0427 0.0427
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0359 0.0359
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0059 0.0494 1
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0017 0.0051 0.0051
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0059 0.0494 1
Schistosoma mansoni serine/threonine protein kinase 0.0059 0.0494 0.0494
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0078 0.0703 1
Schistosoma mansoni hypothetical protein 0.0013 0.0016 0.0016
Echinococcus granulosus twitchin 0.0057 0.0478 0.0478
Entamoeba histolytica hypothetical protein 0.0095 0.0882 0.9569
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0027 0.0161 0.1191
Brugia malayi hypothetical protein 0.0488 0.503 0.503
Echinococcus granulosus phosphatase and tensin 0.0095 0.0882 0.0882
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0078 0.0703 1
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0078 0.0703 1
Schistosoma mansoni tensin 0.0095 0.0882 0.0882
Schistosoma mansoni ap endonuclease 0.0022 0.011 0.011
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0078 0.0703 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0359 0.0359
Leishmania major hypothetical protein, conserved 0.003 0.0189 0.1031
Plasmodium vivax ataxin-2 like protein, putative 0.003 0.0189 0.1543
Echinococcus multilocularis sterol regulatory element binding protein 0.0042 0.0322 0.0322
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0078 0.0703 1
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0024 0.0126 0.0991
Echinococcus granulosus sterol regulatory element binding protein 0.0042 0.0322 0.0322
Echinococcus multilocularis 0.0054 0.0443 0.0443
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0193 0.1911 0.1911
Schistosoma mansoni hypothetical protein 0.01 0.0927 0.0927
Loa Loa (eye worm) hypothetical protein 0.0859 0.8942 0.8942
Onchocerca volvulus 0.0014 0.0022 0.0239
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0047 0.0367 0.0367
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0871 0.9071 0.9071
Entamoeba histolytica hypothetical protein 0.0036 0.0256 0.1814
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0059 0.0494 0.4978
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0059 0.0494 0.6484
Echinococcus multilocularis dual specificity protein kinase clk2 0.0059 0.0494 0.0494
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0014 0.0022 0.0022
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0059 0.0494 0.0494
Loa Loa (eye worm) hypothetical protein 0.0047 0.0367 0.0367
Loa Loa (eye worm) STE/STE11/MEKK2 protein kinase 0.0014 0.0022 0.0022
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0047 0.0367 0.0367
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0099 0.0917 1
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0059 0.0494 0.4978
Loa Loa (eye worm) hypothetical protein 0.0047 0.0367 0.0367
Echinococcus multilocularis neuroglian 0.0052 0.0427 0.0427
Loa Loa (eye worm) hypothetical protein 0.0018 0.0063 0.0063
Entamoeba histolytica Pten 3-phosphoinositide phosphatase, putative 0.0095 0.0882 0.9569
Schistosoma mansoni ap endonuclease 0.0022 0.011 0.011
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0126 0.0991
Echinococcus granulosus expressed conserved protein 0.0093 0.0854 0.0854
Trypanosoma cruzi tyrosine phosphatase isoform, putative 0.0095 0.0882 1
Echinococcus multilocularis polycomb protein SCMH1 0.0048 0.038 0.038
Echinococcus multilocularis histone acetyltransferase MYST2 0.0054 0.045 0.045

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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