Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma cruzi | phosphatidylinositol kinase related protein, putative | 0.005 | 0.0358 | 0.4849 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0127 | 0.2852 | 0.4997 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0349 | 1 | 1 |
Schistosoma mansoni | myelin transcription factor 1 myt1 | 0.0061 | 0.0737 | 0.079 |
Echinococcus granulosus | geminin | 0.0184 | 0.4683 | 0.8322 |
Entamoeba histolytica | hypothetical protein | 0.0058 | 0.0619 | 0.0512 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0056 | 0.0575 | 0.1593 |
Toxoplasma gondii | FATC domain-containing protein | 0.0058 | 0.0619 | 1 |
Leishmania major | phosphatidylinositol kinase related protein, putative | 0.0042 | 0.0115 | 1 |
Echinococcus multilocularis | serine protein kinase ATM | 0.0058 | 0.0619 | 0.0941 |
Loa Loa (eye worm) | hypothetical protein | 0.0061 | 0.0737 | 0.2042 |
Schistosoma mansoni | hypothetical protein | 0.0328 | 0.9324 | 1 |
Treponema pallidum | fructose-bisphosphate aldolase | 0.0349 | 1 | 0.5 |
Schistosoma mansoni | ataxia telangiectasia mutated (atm)-related | 0.0042 | 0.0113 | 0.0121 |
Loa Loa (eye worm) | hypothetical protein | 0.0087 | 0.1552 | 0.4301 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0077 | 0.1222 | 0.2037 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0349 | 1 | 1 |
Loa Loa (eye worm) | MBCTL1 | 0.0061 | 0.0737 | 0.2042 |
Echinococcus granulosus | polycomb protein SCMH1 | 0.0054 | 0.0496 | 0.0719 |
Echinococcus granulosus | SAM and MBT domain containing protein | 0.0054 | 0.0496 | 0.0719 |
Brugia malayi | PHD-finger family protein | 0.0053 | 0.0467 | 0.1196 |
Trypanosoma brucei | phosphatidylinositol kinase related protein, putative | 0.0058 | 0.0619 | 1 |
Schistosoma mansoni | sex comb on midleg homolog | 0.0054 | 0.0496 | 0.0532 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.0042 | 0.0113 | 0.0313 |
Loa Loa (eye worm) | hypothetical protein | 0.0091 | 0.1683 | 0.4664 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0349 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0184 | 0.4683 | 0.5023 |
Echinococcus multilocularis | FKBP12 rapamycin complex associated protein | 0.0042 | 0.0113 | 0.0022 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0349 | 1 | 1 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.0042 | 0.0113 | 0.0313 |
Echinococcus multilocularis | polycomb protein SCMH1 | 0.0054 | 0.0496 | 0.0719 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0077 | 0.1222 | 0.2037 |
Echinococcus granulosus | phosphatidylinositol 3 and 4 kinase | 0.0042 | 0.0113 | 0.0022 |
Brugia malayi | Bromodomain containing protein | 0.0082 | 0.1385 | 0.3549 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0358 | 0.0993 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0349 | 1 | 1 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0048 | 0.0304 | 0.0369 |
Echinococcus multilocularis | suppression of tumorigenicity 18 protein | 0.0061 | 0.0737 | 0.1155 |
Onchocerca volvulus | 0.0054 | 0.0496 | 0.5 | |
Schistosoma mansoni | hypothetical protein | 0.0184 | 0.4683 | 0.5023 |
Schistosoma mansoni | zinc finger protein | 0.0042 | 0.0101 | 0.0108 |
Mycobacterium tuberculosis | Probable fructose-bisphosphate aldolase Fba | 0.017 | 0.425 | 0.5 |
Schistosoma mansoni | bromodomain containing protein | 0.0135 | 0.3098 | 0.3322 |
Onchocerca volvulus | Polycomb protein Sfmbt homolog | 0.0054 | 0.0496 | 0.5 |
Echinococcus granulosus | histone acetyltransferase MYST2 | 0.0061 | 0.0737 | 0.1155 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0042 | 0.0113 | 0.0289 |
Mycobacterium leprae | Probable fructose bisphosphate aldolase Fba | 0.017 | 0.425 | 0.5 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0044 | 0.0173 | 0.048 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0575 | 0.1593 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0349 | 1 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0058 | 0.0619 | 0.0512 |
Schistosoma mansoni | ataxia telangiectasia mutated (atm) | 0.0058 | 0.0619 | 0.0664 |
Echinococcus multilocularis | geminin | 0.0184 | 0.4683 | 0.8322 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0058 | 0.0619 | 0.1586 |
Schistosoma mansoni | hypothetical protein | 0.0044 | 0.0173 | 0.0186 |
Mycobacterium ulcerans | fructose-bisphosphate aldolase | 0.017 | 0.425 | 0.5 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0349 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0151 | 0.3608 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0349 | 1 | 1 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0127 | 0.2852 | 0.4997 |
Echinococcus granulosus | serine protein kinase ATM | 0.0058 | 0.0619 | 0.0941 |
Schistosoma mansoni | sex comb on midleg homolog | 0.0054 | 0.0496 | 0.0532 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0056 | 0.0575 | 0.1473 |
Brugia malayi | mbt repeat family protein | 0.0054 | 0.0496 | 0.1272 |
Echinococcus multilocularis | histone acetyltransferase MYST2 | 0.0061 | 0.0737 | 0.1155 |
Echinococcus granulosus | suppression of tumorigenicity 18 protein | 0.0061 | 0.0737 | 0.1155 |
Loa Loa (eye worm) | hypothetical protein | 0.0082 | 0.1389 | 0.3851 |
Echinococcus multilocularis | endonuclease exonuclease phosphatase | 0.0213 | 0.5608 | 1 |
Trypanosoma cruzi | phosphatidylinositol kinase related protein, putative | 0.0058 | 0.0619 | 1 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0048 | 0.0304 | 0.0326 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0048 | 0.0304 | 0.0369 |
Echinococcus granulosus | endonuclease exonuclease phosphatase | 0.0213 | 0.5608 | 1 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0056 | 0.0575 | 0.1473 |
Echinococcus granulosus | FKBP12 rapamycin complex associated protein | 0.0042 | 0.0113 | 0.0022 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.0496 | 0.1376 |
Schistosoma mansoni | scm-relatedprotein containing 4 mbt domains (sfmbt) | 0.0054 | 0.0496 | 0.0532 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0042 | 0.0113 | 0.0289 |
Schistosoma mansoni | phosphatidylinositol 3-and 4-kinase | 0.0042 | 0.0113 | 0.0121 |
Brugia malayi | mbt repeat family protein | 0.0054 | 0.0496 | 0.1272 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0349 | 1 | 1 |
Echinococcus multilocularis | SAM and MBT domain containing protein | 0.0054 | 0.0496 | 0.0719 |
Giardia lamblia | Fructose-bisphosphate aldolase | 0.0349 | 1 | 1 |
Brugia malayi | Bromodomain containing protein | 0.016 | 0.3901 | 1 |
Loa Loa (eye worm) | mbt repeat family protein | 0.0054 | 0.0496 | 0.1376 |
Trypanosoma cruzi | phosphatidylinositol kinase related protein, putative | 0.0042 | 0.0115 | 0.0052 |
Brugia malayi | C2-HC type zinc finger protein C.e-MyT1 | 0.0061 | 0.0737 | 0.1889 |
Echinococcus multilocularis | phosphatidylinositol 3 and 4 kinase | 0.0042 | 0.0113 | 0.0022 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.