Detailed information for compound 650857

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 377.397 | Formula: C20H19N5O3
  • H donors: 2 H acceptors: 4 LogP: 3.28 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCc1ccc(cc1)c1n[nH]c(c1)C(=O)NN=C(c1ccc(cc1)[N+](=O)[O-])C
  • InChi: 1S/C20H19N5O3/c1-3-14-4-6-16(7-5-14)18-12-19(23-22-18)20(26)24-21-13(2)15-8-10-17(11-9-15)25(27)28/h4-12H,3H2,1-2H3,(H,22,23)(H,24,26)/b21-13-
  • InChiKey: PGHKNQAVBVTYAI-BKUYFWCQSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.011 0.2025 0.4114
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0032 0.042 0.0347
Echinococcus granulosus solute carrier family 22 0.0015 0.0075 0.0047
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0036 0.0496 0.0973
Brugia malayi hypothetical protein 0.0051 0.0811 0.1559
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.0015 0.0075 0.0736
Echinococcus multilocularis muscleblind protein 0.0145 0.2731 0.2711
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.016 0.2472
Loa Loa (eye worm) hypothetical protein 0.0019 0.016 0.029
Toxoplasma gondii ABC1 family protein 0.0036 0.0496 0.0726
Echinococcus multilocularis glycine receptor subunit beta 0.011 0.2025 0.2003
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0032 0.0433 0.085
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.011 0.2025 0.4068
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0033 0.0444 0.0873
Trypanosoma brucei THT1 - hexose transporter, putative 0.0033 0.0441 0.8246
Loa Loa (eye worm) hypothetical protein 0.0051 0.0811 0.1625
Schistosoma mansoni lysyl-tRNA synthetase 0.0024 0.0253 0.018
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.016 0.2472
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0251 0.4897 0.4883
Trypanosoma brucei hypothetical protein, conserved 0.0036 0.0496 0.9368
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0106 0.1933 0.1911
Trypanosoma cruzi hexose transporter 0.0033 0.0441 0.8107
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0134 0.2517 0.246
Echinococcus granulosus glycine receptor subunit alpha 1 0.011 0.2025 0.2003
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0015 0.0075 0.0047
Entamoeba histolytica hypothetical protein 0.0059 0.0985 1
Loa Loa (eye worm) beta-lactamase 0.0036 0.0496 0.098
Loa Loa (eye worm) hypothetical protein 0.0015 0.0075 0.0117
Echinococcus multilocularis dna polymerase kappa 0.0019 0.016 0.0132
Loa Loa (eye worm) hypothetical protein 0.0036 0.0496 0.098
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0015 0.0084 0.0921
Leishmania major DNA polymerase kappa, putative 0.0019 0.016 0.0401
Echinococcus granulosus expressed protein 0.0033 0.0444 0.0417
Schistosoma mansoni hypothetical protein 0.0501 1 1
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0134 0.2517 0.5121
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0015 0.0084 0.02
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0015 0.0084 0.0056
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.0303 0.0584
Trichomonas vaginalis ap endonuclease, putative 0.0037 0.052 0.2398
Onchocerca volvulus 0.0026 0.0303 0.0473
Loa Loa (eye worm) hypothetical protein 0.0051 0.0811 0.1625
Loa Loa (eye worm) sugar transporter 0.0106 0.1933 0.3925
Schistosoma mansoni terminal deoxycytidyl transferase 0.0019 0.016 0.0085
Leishmania major hypothetical protein, conserved 0.0036 0.0496 0.1991
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.018 0.3456 0.3407
Loa Loa (eye worm) hypothetical protein 0.0015 0.0075 0.0117
Loa Loa (eye worm) hypothetical protein 0.0059 0.0985 0.1983
Echinococcus granulosus solute carrier family 22 0.0015 0.0075 0.0047
Loa Loa (eye worm) hypothetical protein 0.011 0.2025 0.4114
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0171 0.3265 0.3595
Trichomonas vaginalis esterase, putative 0.0036 0.0496 0.2267
Schistosoma mansoni glucose transport protein 0.0106 0.1933 0.1872
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.018 0.3456 0.3407
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0032 0.0433 0.0406
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0051 0.0811 0.1559
Plasmodium falciparum lysine--tRNA ligase 0.0024 0.0253 0.0201
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0106 0.1933 0.1911
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0015 0.0084 0.0009
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0031 0.0401 0.0375
Echinococcus multilocularis glycine receptor subunit beta 0.011 0.2025 0.2003
Plasmodium falciparum calcium-dependent protein kinase 5 0.0032 0.0433 0.0404
Loa Loa (eye worm) major facilitator superfamily transporter 0.0015 0.0075 0.0117
Loa Loa (eye worm) hypothetical protein 0.0051 0.0811 0.1625
Schistosoma mansoni hypothetical protein 0.0031 0.0401 0.0329
Onchocerca volvulus 0.011 0.2025 0.4044
Echinococcus multilocularis calcium dependent protein kinase 0.003 0.0392 0.0365
Echinococcus multilocularis solute carrier family 22 0.0015 0.0075 0.0047
Echinococcus granulosus glycine receptor subunit alpha 1 0.011 0.2025 0.2003
Loa Loa (eye worm) hypothetical protein 0.011 0.2025 0.4114
Schistosoma mansoni protein kinase 0.0032 0.0433 0.0361
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0036 0.0496 0.2265
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0032 0.0433 0.0406
Trypanosoma brucei glucose transporter, putative 0.0033 0.0441 0.8246
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0024 0.0253 0.1157
Trypanosoma brucei glucose transporter, putative 0.0033 0.0441 0.8246
Loa Loa (eye worm) hypothetical protein 0.0051 0.0811 0.1625
Echinococcus granulosus glycine receptor subunit beta 0.011 0.2025 0.2003
Loa Loa (eye worm) transcription factor SMAD2 0.0115 0.2127 0.4322
Loa Loa (eye worm) hypothetical protein 0.0015 0.0075 0.0117
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0503 0.9463
Mycobacterium ulcerans lipase LipD 0.0036 0.0496 0.2265
Mycobacterium ulcerans aldehyde dehydrogenase 0.0118 0.2191 1
Onchocerca volvulus 0.018 0.3456 0.7012
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.011 0.2025 0.4068
Loa Loa (eye worm) hypothetical protein 0.0036 0.0496 0.098
Mycobacterium ulcerans sugar transporter 0.0015 0.0075 0.0342
Onchocerca volvulus 0.018 0.3456 0.7012
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.011 0.2025 0.4114
Schistosoma mansoni acetylcholine receptor subunit beta 0.0051 0.0811 0.0741
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.011 0.2025 0.2003
Loa Loa (eye worm) hypothetical protein 0.0026 0.0293 0.0564
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0037 0.052 0.0494
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.0015 0.0075 0.0342
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0032 0.0433 0.8072
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.011 0.2025 0.2003
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.011 0.2025 0.4114
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.016 0.2472
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0015 0.0084 0.0056
Mycobacterium tuberculosis Probable hydrolase 0.0036 0.0496 0.0973
Loa Loa (eye worm) hypothetical protein 0.011 0.2025 0.4114
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.011 0.2025 0.4114
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0032 0.042 0.757
Schistosoma mansoni protein kinase 0.0032 0.0433 0.0361
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0037 0.052 1
Loa Loa (eye worm) hypothetical protein 0.0015 0.0075 0.0117
Loa Loa (eye worm) MH2 domain-containing protein 0.0115 0.2127 0.4322
Schistosoma mansoni neurotransmitter gated ion channel 0.0059 0.0985 0.0917
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0036 0.0496 0.098
Mycobacterium leprae Probable lipase LipE 0.0036 0.0496 1
Leishmania major glucose transporter, lmgt3 0.0033 0.0441 0.1732
Loa Loa (eye worm) hypothetical protein 0.0024 0.0253 0.0483
Echinococcus multilocularis tumor protein p63 0.0328 0.6466 0.6456
Loa Loa (eye worm) hypothetical protein 0.0051 0.0811 0.1625
Echinococcus multilocularis isocitrate dehydrogenase 0.0015 0.0084 0.0056
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0098 0.1763 0.3526
Loa Loa (eye worm) hypothetical protein 0.0051 0.0811 0.1625
Leishmania major protein kinase, putative 0.0032 0.0433 0.1692
Trichomonas vaginalis glucose transporter, putative 0.0033 0.0441 0.1973
Leishmania major glucose transporter, lmgt2 0.0033 0.0441 0.1732
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.016 0.2472
Loa Loa (eye worm) hypothetical protein 0.011 0.2025 0.4114
Brugia malayi major facilitator superfamily protein 0.0015 0.0075 0.0039
Toxoplasma gondii isocitrate dehydrogenase 0.0015 0.0084 0.0016
Entamoeba histolytica hypothetical protein 0.0024 0.0253 0.1136
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0032 0.0433 0.0404
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0496 0.2267
Schistosoma mansoni nAChR subunit 0.0051 0.0811 0.0741
Loa Loa (eye worm) hypothetical protein 0.0032 0.042 0.0823
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0251 0.4897 1
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0118 0.2191 0.2169
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0032 0.042 0.0347
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.002 0.0181 0.0244
Schistosoma mansoni neurotransmitter gated ion channel 0.0051 0.0811 0.0741
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0051 0.0811 0.1559
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0171 0.3265 0.5495
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.016 0.1875
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0037 0.052 0.2375
Echinococcus granulosus muscleblind protein 0.0145 0.2731 0.2711
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0106 0.1933 0.1911
Echinococcus multilocularis expressed protein 0.0033 0.0444 0.0417
Brugia malayi Intermediate filament tail domain containing protein 0.0026 0.0303 0.051
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0037 0.052 1
Brugia malayi Cation transporter family protein 0.018 0.3456 0.7023
Mycobacterium ulcerans beta-lactamase 0.0036 0.0496 0.2265
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.011 0.2025 0.4068
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.011 0.2025 0.2003
Brugia malayi Sugar transporter family protein 0.0015 0.0075 0.0039
Trypanosoma brucei glucose transporter, putative 0.0033 0.0441 0.8246
Entamoeba histolytica protein kinase, putative 0.0032 0.0433 0.331
Echinococcus granulosus nAChR subunit 0.011 0.2025 0.2003
Loa Loa (eye worm) hypothetical protein 0.011 0.2025 0.4114
Brugia malayi hypothetical protein 0.0015 0.0075 0.0039
Loa Loa (eye worm) hypothetical protein 0.0013 0.0028 0.002
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.011 0.2025 0.4114
Echinococcus granulosus intermediate filament protein 0.0026 0.0303 0.0276
Plasmodium falciparum mitogen-activated protein kinase 2 0.0171 0.3265 0.3595
Loa Loa (eye worm) hypothetical protein 0.011 0.2025 0.4114
Echinococcus granulosus inositol monophosphatase 1 0.0036 0.0503 0.0476
Echinococcus granulosus lamin 0.0026 0.0303 0.0276
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0037 0.052 0.9865
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0134 0.2517 0.2496
Echinococcus granulosus tumor protein p63 0.0328 0.6466 0.6456
Trichomonas vaginalis sugar transporter, putative 0.0033 0.0441 0.1973
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.016 0.2472
Trypanosoma cruzi hexose transporter, putative 0.0033 0.0441 0.8107
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0019 0.016 0.0085
Brugia malayi beta-lactamase family protein 0.0036 0.0496 0.0909
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0503 0.2022
Toxoplasma gondii isocitrate dehydrogenase 0.0015 0.0084 0.0016
Mycobacterium ulcerans hypothetical protein 0.0036 0.0496 0.2265
Loa Loa (eye worm) hypothetical protein 0.0036 0.0496 0.098
Schistosoma mansoni nAChR subunit 0.011 0.2025 0.1965
Schistosoma mansoni aldehyde dehydrogenase 0.0118 0.2191 0.2132
Loa Loa (eye worm) hypothetical protein 0.0098 0.1763 0.3576
Onchocerca volvulus 0.0059 0.0985 0.1888
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0496 0.2267
Schistosoma mansoni hypothetical protein 0.0031 0.0401 0.0329
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0037 0.052 0.1029
Brugia malayi Sugar transporter family protein 0.0015 0.0075 0.0039
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0021 0.0194 0.0641
Brugia malayi Latrophilin receptor protein 2 0.0031 0.0401 0.0713
Schistosoma mansoni DNA polymerase eta 0.0019 0.016 0.0085
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.011 0.2025 0.4068
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.0051 0.0811 0.1625
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0037 0.052 0.0494
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0019 0.016 0.0401
Echinococcus multilocularis glycine receptor subunit alpha 1 0.011 0.2025 0.2003
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0031 0.0401 0.0375
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0098 0.1763 0.3576
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.011 0.2025 0.2003
Loa Loa (eye worm) intermediate filament protein 0.0026 0.0303 0.0584
Brugia malayi Isocitrate dehydrogenase 0.0015 0.0084 0.0058
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0032 0.042 0.1855
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.016 0.0729
Brugia malayi Cation transporter family protein 0.011 0.2025 0.4068
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0019 0.016 0.0132
Loa Loa (eye worm) hypothetical protein 0.0051 0.0811 0.1625
Toxoplasma gondii exonuclease III APE 0.0037 0.052 0.0768
Brugia malayi Calcitonin receptor-like protein seb-1 0.0098 0.1763 0.3526
Trypanosoma brucei glucose transporter, putative 0.0033 0.0441 0.8246
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0503 0.9502
Loa Loa (eye worm) hypothetical protein 0.0051 0.0811 0.1625
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0037 0.0527 1
Brugia malayi Muscleblind-like protein 0.0145 0.2731 0.5525
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0051 0.0811 0.0785
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0441 0.1973
Loa Loa (eye worm) hypothetical protein 0.013 0.2416 0.4915
Schistosoma mansoni hypothetical protein 0.0501 1 1
Toxoplasma gondii protein kinase, putative 0.0299 0.588 1
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0134 0.2517 0.5082
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0024 0.0253 0.395
Schistosoma mansoni aldehyde dehydrogenase 0.0118 0.2191 0.2132
Echinococcus multilocularis glycine receptor subunit alpha 1 0.011 0.2025 0.2003
Mycobacterium tuberculosis Conserved hypothetical protein 0.0019 0.016 0.0196
Schistosoma mansoni nAChR subunit 0.011 0.2025 0.1965
Loa Loa (eye worm) hypothetical protein 0.0015 0.0075 0.0117
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0019 0.016 0.029
Echinococcus multilocularis inositol monophosphatase 1 0.0036 0.0503 0.0476
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0106 0.1933 0.1911
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.016 0.2472
Loa Loa (eye worm) hypothetical protein 0.0051 0.0811 0.1625
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.016 0.2472
Schistosoma mansoni hypothetical protein 0.0067 0.1133 0.1066
Echinococcus granulosus solute carrier family 22 0.0015 0.0075 0.0047
Loa Loa (eye worm) hypothetical protein 0.011 0.2025 0.4114
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0251 0.4897 0.4883
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.016 0.1875
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0032 0.0433 0.0404
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0496 0.9318
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.011 0.2025 0.4068
Treponema pallidum exodeoxyribonuclease (exoA) 0.0037 0.052 1
Plasmodium falciparum hexose transporter 0.0106 0.1933 0.2094
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0036 0.0503 0.2295
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0037 0.052 0.9855
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0059 0.0985 0.0917
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0051 0.0811 0.0785
Loa Loa (eye worm) hypothetical protein 0.0015 0.0075 0.0117
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.016 0.1875
Loa Loa (eye worm) acetylcholine receptor protein 0.0051 0.0811 0.1625
Schistosoma mansoni nAChR subunit 0.011 0.2025 0.1965
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0496 0.2267
Loa Loa (eye worm) hypothetical protein 0.0015 0.0075 0.0117
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0032 0.0426 0.0811
Brugia malayi beta-lactamase family protein 0.0036 0.0496 0.0909
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0496 0.0424
Echinococcus granulosus GPCR family 2 0.0031 0.0401 0.0375
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0037 0.0527 1
Loa Loa (eye worm) hypothetical protein 0.0051 0.0811 0.1625
Trypanosoma brucei DNA polymerase eta, putative 0.0019 0.016 0.2472
Plasmodium falciparum calcium-dependent protein kinase 1 0.0032 0.0433 0.0404
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0019 0.016 0.0132
Loa Loa (eye worm) hypothetical protein 0.0059 0.0985 0.1983
Echinococcus multilocularis lamin 0.0026 0.0303 0.0276
Loa Loa (eye worm) hypothetical protein 0.011 0.2025 0.4114
Loa Loa (eye worm) hypothetical protein 0.0036 0.0496 0.098
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0024 0.0253 0.0961
Mycobacterium tuberculosis Conserved protein 0.0036 0.0496 0.0973
Brugia malayi latrophilin 2 splice variant baaae 0.0067 0.1133 0.2224
Onchocerca volvulus 0.0059 0.0985 0.1888
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0444 0.1985
Loa Loa (eye worm) hypothetical protein 0.011 0.2025 0.4114
Schistosoma mansoni cellular tumor antigen P53 0.0048 0.0751 0.0681
Loa Loa (eye worm) hypothetical protein 0.018 0.3456 0.7047
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0032 0.0426 0.7777
Toxoplasma gondii aldehyde dehydrogenase 0.0118 0.2191 0.3645
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0059 0.0985 0.192
Plasmodium falciparum proline--tRNA ligase 0.0037 0.0527 0.051
Schistosoma mansoni lamin 0.0026 0.0303 0.023
Mycobacterium ulcerans aldehyde dehydrogenase 0.0118 0.2191 1
Trichomonas vaginalis inositol monophosphatase, putative 0.0036 0.0503 0.2303
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.016 0.2472
Giardia lamblia DINP protein human, muc B family 0.0019 0.016 0.1902
Brugia malayi hypothetical protein 0.0015 0.0075 0.0039
Mycobacterium tuberculosis Conserved protein 0.0036 0.0496 0.0973
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0059 0.0985 0.192
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.002 0.0181 0.0244
Schistosoma mansoni ap endonuclease 0.0037 0.052 0.0449
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0118 0.2191 0.4887
Toxoplasma gondii lysine-tRNA ligase 0.0024 0.0253 0.0308
Echinococcus multilocularis beta LACTamase domain containing family member 0.0036 0.0496 0.047
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.016 0.0729
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.011 0.2025 0.4068
Trichomonas vaginalis sugar transporter, putative 0.0033 0.0441 0.1973
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.011 0.2025 0.4068
Loa Loa (eye worm) hypothetical protein 0.0145 0.2731 0.556
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0037 0.052 0.103
Leishmania major glucose transporter/membrane transporter D2, putative 0.0033 0.0441 0.1732
Schistosoma mansoni nAChR subunit 0.0051 0.0811 0.0741
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0134 0.2517 0.246
Schistosoma mansoni ap endonuclease 0.0037 0.052 0.0449
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.011 0.2025 0.1965
Loa Loa (eye worm) hypothetical protein 0.011 0.2025 0.4114
Trypanosoma cruzi hexose transporter, putative 0.0033 0.0441 0.8107
Loa Loa (eye worm) hypothetical protein 0.0015 0.0075 0.0117
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0496 0.2267
Echinococcus multilocularis muscleblind protein 1 0.0145 0.2731 0.2711
Echinococcus multilocularis GPCR, family 2 0.0031 0.0401 0.0375
Schistosoma mansoni protein kinase 0.0032 0.0433 0.0361
Loa Loa (eye worm) GABA receptor subunit 0.0059 0.0985 0.1983
Echinococcus multilocularis General substrate transporter 0.0091 0.1629 0.1606
Brugia malayi MH2 domain containing protein 0.0115 0.2127 0.4277
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0134 0.2517 0.2496
Mycobacterium ulcerans integral membrane transport protein 0.0015 0.0075 0.0342
Loa Loa (eye worm) latrophilin receptor protein 2 0.0031 0.0401 0.0785
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.011 0.2025 0.2003
Leishmania major DNA polymerase eta, putative 0.0019 0.016 0.0401
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0496 0.2267
Echinococcus multilocularis musashi 0.0026 0.0303 0.0276
Mycobacterium tuberculosis Conserved protein 0.0036 0.0496 0.0973
Trichomonas vaginalis DNA polymerase eta, putative 0.0019 0.016 0.0456
Loa Loa (eye worm) LGC-31 protein 0.011 0.2025 0.4114
Echinococcus granulosus synaptic vesicle 2 protein 0.0015 0.0075 0.0047
Leishmania major glucose transporter, lmgt1 0.0033 0.0441 0.1732
Trypanosoma brucei THT1 - hexose transporter, putative 0.0033 0.0441 0.8246
Plasmodium falciparum protein kinase 6 0.0449 0.8948 1
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0015 0.0084 0.0043
Brugia malayi hypothetical protein 0.0051 0.0811 0.1559
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0118 0.2191 0.2169
Brugia malayi Sugar transporter family protein 0.0106 0.1933 0.3877
Trypanosoma brucei sugar transporter, putative 0.0015 0.0075 0.0736
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0037 0.052 0.9855
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.011 0.2025 0.2003
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0032 0.0428 0.3249
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.016 0.2472
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0059 0.0985 0.0917
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0032 0.0433 0.0779
Trypanosoma brucei THT1 - hexose transporter, putative 0.0033 0.0441 0.8246
Schistosoma mansoni lysyl-tRNA synthetase 0.0024 0.0253 0.018
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.011 0.2025 0.4068
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0015 0.0084 0.02
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0015 0.0084 0.001
Trypanosoma brucei glucose transporter, putative 0.0033 0.0441 0.8246
Loa Loa (eye worm) hypothetical protein 0.011 0.2025 0.4114
Trypanosoma brucei glucose transporter 1E 0.0033 0.0441 0.8246
Plasmodium vivax lysine--tRNA ligase, putative 0.0024 0.0253 0.0201
Loa Loa (eye worm) hypothetical protein 0.0026 0.0303 0.0584
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0019 0.016 0.0456
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0106 0.1933 0.1911
Brugia malayi isocitrate dehydrogenase 0.0015 0.0084 0.0058
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.016 0.2472
Loa Loa (eye worm) hypothetical protein 0.0067 0.1133 0.2284
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0014 0.0056 0.0078
Onchocerca volvulus Putative nachr subunit 0.0251 0.4897 1
Schistosoma mansoni inositol monophosphatase 0.0036 0.0503 0.0431
Plasmodium vivax CDK-related protein kinase 6, putative 0.0449 0.8948 1
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.011 0.2025 0.4114
Onchocerca volvulus 0.0051 0.0811 0.1526
Trypanosoma cruzi hexose transporter, putative 0.0018 0.0137 0.1383
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0032 0.0433 0.0406
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0032 0.0433 0.085
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0032 0.0433 0.0406
Brugia malayi hypothetical protein 0.0051 0.0811 0.1559
Loa Loa (eye worm) hypothetical protein 0.0015 0.0075 0.0117
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0015 0.0084 0.001
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0496 0.0424
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0032 0.0428 0.7808
Onchocerca volvulus 0.011 0.2025 0.4044
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0503 0.9463
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0032 0.0433 0.0406
Onchocerca volvulus 0.0051 0.0811 0.1526
Loa Loa (eye worm) hypothetical protein 0.0059 0.0985 0.1983
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0051 0.0811 0.1625
Echinococcus granulosus lysyl tRNA synthetase 0.0024 0.0253 0.0226
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.011 0.2025 0.4068
Onchocerca volvulus 0.0026 0.0303 0.0473
Schistosoma mansoni hypothetical protein 0.0106 0.1933 0.1872
Toxoplasma gondii peptidylprolyl isomerase 0.0032 0.0428 0.0608
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0036 0.0496 0.0909
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0037 0.0527 0.2137
Trichomonas vaginalis conserved hypothetical protein 0.0106 0.1933 1
Brugia malayi hypothetical protein 0.0051 0.0811 0.1559
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0032 0.0433 0.0617
Schistosoma mansoni neurotransmitter gated ion channel 0.0051 0.0811 0.0741
Echinococcus granulosus nAChR subunit 0.0059 0.0985 0.096
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0118 0.2191 1
Schistosoma mansoni hypothetical protein 0.0031 0.0401 0.0329
Schistosoma mansoni hypothetical protein 0.0031 0.0401 0.0329
Echinococcus multilocularis synaptic vesicle 2 protein 0.0015 0.0075 0.0047
Loa Loa (eye worm) hypothetical protein 0.0026 0.0298 0.0574
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.0051 0.0811 0.0785
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0032 0.0433 0.0406
Echinococcus multilocularis nAChR subunit 0.0059 0.0985 0.096
Loa Loa (eye worm) hypothetical protein 0.0059 0.0985 0.1983
Onchocerca volvulus 0.0036 0.0496 0.0874
Mycobacterium ulcerans esterase/lipase LipP 0.0036 0.0496 0.2265
Loa Loa (eye worm) hypothetical protein 0.0015 0.0075 0.0117
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0059 0.0985 0.192
Brugia malayi Major Facilitator Superfamily protein 0.0015 0.0075 0.0039
Loa Loa (eye worm) hypothetical protein 0.011 0.2025 0.4114
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.011 0.2025 0.2003
Onchocerca volvulus 0.0051 0.0811 0.1526
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.016 0.0214
Plasmodium vivax proline--tRNA ligase, putative 0.0037 0.0527 0.051
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0015 0.0084 0.0921
Loa Loa (eye worm) hypothetical protein 0.0059 0.0985 0.1983
Echinococcus granulosus beta LACTamase domain containing family member 0.0036 0.0496 0.047
Loa Loa (eye worm) hypothetical protein 0.0251 0.4897 1
Trypanosoma brucei glucose transporter, putative 0.0033 0.0441 0.8246
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0036 0.0496 0.0973
Loa Loa (eye worm) ACC-1 protein 0.011 0.2025 0.4114
Giardia lamblia Lysyl-tRNA synthetase 0.0024 0.0253 0.4008
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0106 0.1933 0.1911
Schistosoma mansoni lamin 0.0026 0.0303 0.023
Echinococcus granulosus General substrate transporter 0.0091 0.1629 0.1606
Brugia malayi Inositol-1 0.0036 0.0503 0.0923
Echinococcus multilocularis lamin dm0 0.0026 0.0303 0.0276
Loa Loa (eye worm) hypothetical protein 0.0048 0.0751 0.1502
Trichomonas vaginalis glucose transporter, putative 0.0033 0.0441 0.1973
Loa Loa (eye worm) hypothetical protein 0.0051 0.0811 0.1625
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0024 0.0253 0.4395
Brugia malayi excitatory GABA receptor EXP-1A 0.011 0.2025 0.4068
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0024 0.0253 0.2306
Mycobacterium tuberculosis Probable lipase LipE 0.0036 0.0496 0.0973
Trichomonas vaginalis ap endonuclease, putative 0.0037 0.052 0.2398
Trypanosoma cruzi hexose transporter, putative 0.0033 0.0441 0.8107
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0037 0.052 0.0502
Trypanosoma brucei glucose transporter 2A 0.0033 0.0441 0.8246
Onchocerca volvulus 0.018 0.3456 0.7012
Brugia malayi major facilitator superfamily protein 0.0015 0.0075 0.0039
Loa Loa (eye worm) hypothetical protein 0.0051 0.0811 0.1625
Brugia malayi Cam kinase protein 1 0.0032 0.0433 0.0779
Echinococcus multilocularis geminin 0.0501 1 1
Trypanosoma brucei unspecified product 0.0019 0.016 0.2472
Loa Loa (eye worm) hypothetical protein 0.0059 0.0985 0.1983
Schistosoma mansoni inositol monophosphatase 0.0036 0.0503 0.0431
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0251 0.4897 0.4883
Trichomonas vaginalis rotamase, putative 0.0032 0.0428 0.19
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0037 0.052 0.0502
Loa Loa (eye worm) hypothetical protein 0.0051 0.0811 0.1625
Trypanosoma brucei glucose transporter, putative 0.0033 0.0441 0.8246
Loa Loa (eye worm) hypothetical protein 0.0036 0.0496 0.098
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0019 0.016 0.0196
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0059 0.0985 0.192
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0032 0.042 0.0393
Trichomonas vaginalis CAMK family protein kinase 0.0032 0.0433 0.1927
Loa Loa (eye worm) hypothetical protein 0.0015 0.0075 0.0117
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0032 0.042 0.0751
Loa Loa (eye worm) ACC-1 protein 0.011 0.2025 0.4114
Plasmodium falciparum calcium-dependent protein kinase 2 0.0032 0.0433 0.0404
Schistosoma mansoni nAChR subunit 0.011 0.2025 0.1965
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0015 0.0084 0.0056
Echinococcus granulosus glycine receptor subunit beta 0.011 0.2025 0.2003
Schistosoma mansoni nAChR subunit 0.011 0.2025 0.1965
Echinococcus multilocularis solute carrier family 22 0.0015 0.0075 0.0047
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0032 0.042 0.0751
Loa Loa (eye worm) hypothetical protein 0.0059 0.0985 0.1983
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0036 0.0496 0.0973
Schistosoma mansoni nAChR subunit 0.011 0.2025 0.1965
Loa Loa (eye worm) isocitrate dehydrogenase 0.0015 0.0084 0.0135
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0037 0.052 0.2106
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0251 0.4897 0.4883
Loa Loa (eye worm) hypothetical protein 0.018 0.3456 0.7047
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0036 0.0503 0.4155
Loa Loa (eye worm) hypothetical protein 0.011 0.2025 0.4114
Brugia malayi hypothetical protein 0.0015 0.0075 0.0039
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.011 0.2025 0.4068
Trichomonas vaginalis rotamase, putative 0.0033 0.0444 0.1985
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0032 0.0433 0.0617
Entamoeba histolytica protein kinase, putative 0.0032 0.0433 0.331
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0251 0.4897 1
Schistosoma mansoni glucose transport protein 0.0106 0.1933 0.1872
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0032 0.042 0.0393
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.011 0.2025 0.1965
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0032 0.042 0.3148
Loa Loa (eye worm) hypothetical protein 0.0015 0.0075 0.0117
Loa Loa (eye worm) hypothetical protein 0.0015 0.0075 0.0117
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.011 0.2025 0.1965
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0032 0.0433 0.0406
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0037 0.0527 0.2137
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0032 0.0433 0.0617
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.011 0.2025 0.4068
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0251 0.4897 0.4883
Loa Loa (eye worm) sugar transporter 0.0015 0.0075 0.0117
Trichomonas vaginalis sugar transporter, putative 0.0033 0.0441 0.1973
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0503 0.2303
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0032 0.0428 0.7808
Schistosoma mansoni glucose transport protein 0.0106 0.1933 0.1872
Echinococcus multilocularis solute carrier family 22 0.0015 0.0075 0.0047
Onchocerca volvulus 0.0048 0.0751 0.1402
Loa Loa (eye worm) bifunctional aminoacyl-tRNA synthetase 0.0013 0.0037 0.0039
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.011 0.2025 0.4068
Trypanosoma brucei glucose transporter, putative 0.0033 0.0441 0.8246
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0227 0.4405 1
Plasmodium falciparum protein kinase 7 0.0299 0.588 0.6542
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.011 0.2025 0.4068
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0134 0.2517 0.246
Mycobacterium leprae conserved hypothetical protein 0.0036 0.0496 1
Echinococcus multilocularis lysyl tRNA synthetase 0.0024 0.0253 0.0226
Mycobacterium tuberculosis Probable lipase LipD 0.0036 0.0496 0.0973
Schistosoma mansoni acetylcholine receptor-related 0.0051 0.0811 0.0741
Leishmania major lysyl-tRNA synthetase, putative 0.0024 0.0253 0.0844
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0033 0.0444 0.0801
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0031 0.0401 0.0375
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0032 0.0433 0.0406
Brugia malayi exodeoxyribonuclease III family protein 0.0037 0.052 0.0959
Echinococcus multilocularis solute carrier family 22 0.0015 0.0075 0.0047
Schistosoma mansoni rotamase 0.0033 0.0444 0.0372
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0251 0.4897 0.4883
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.016 0.2472
Loa Loa (eye worm) hypothetical protein 0.0059 0.0985 0.1983
Brugia malayi intermediate filament protein 0.0026 0.0303 0.051
Mycobacterium tuberculosis Probable esterase LipL 0.0036 0.0496 0.0973
Loa Loa (eye worm) hypothetical protein 0.0145 0.2731 0.556
Loa Loa (eye worm) hypothetical protein 0.0032 0.0433 0.085
Brugia malayi lysyl-tRNA synthetase 0.0024 0.0253 0.0408
Loa Loa (eye worm) major facilitator superfamily transporter 0.0015 0.0075 0.0117
Loa Loa (eye worm) hypothetical protein 0.0036 0.0496 0.098
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.0051 0.0811 0.0785
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.011 0.2025 0.1965
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0496 0.9318
Echinococcus granulosus lamin dm0 0.0026 0.0303 0.0276
Loa Loa (eye worm) hypothetical protein 0.0031 0.0401 0.0785
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0051 0.0811 0.1559
Loa Loa (eye worm) hypothetical protein 0.0051 0.0811 0.1625
Toxoplasma gondii facilitative glucose transporter GT1 0.0106 0.1933 0.3201
Plasmodium vivax hexose transporter 0.0106 0.1933 0.2094
Echinococcus granulosus dna polymerase eta 0.0019 0.016 0.0132
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0037 0.0527 0.0779
Loa Loa (eye worm) hypothetical protein 0.011 0.2025 0.4114
Brugia malayi Major Facilitator Superfamily protein 0.0015 0.0075 0.0039
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0015 0.0084 0.0021
Brugia malayi Major Facilitator Superfamily protein 0.0015 0.0075 0.0039
Plasmodium falciparum calcium-dependent protein kinase 3 0.0032 0.0433 0.0404
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0441 0.1973
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0134 0.2517 0.2496
Plasmodium vivax calcium-dependent protein kinase, putative 0.0032 0.0433 0.0404
Trypanosoma cruzi DNA polymerase eta, putative 0.0019 0.016 0.1875
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.016 0.2472
Plasmodium falciparum calcium-dependent protein kinase 4 0.0032 0.0433 0.0404
Echinococcus granulosus Sugar transporter ERD6 protein 0.0015 0.0075 0.0047
Echinococcus granulosus calcium dependent protein kinase 0.003 0.0392 0.0365
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0032 0.0433 0.0404
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0031 0.0401 0.0713
Brugia malayi beta-lactamase 0.0036 0.0496 0.0909
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0015 0.0084 0.0056
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0031 0.0401 0.0375
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.011 0.2025 0.2003
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.011 0.2025 0.4068
Echinococcus multilocularis nAChR subunit 0.011 0.2025 0.2003
Schistosoma mansoni nAChR subunit 0.011 0.2025 0.1965
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0106 0.1933 0.1911
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.011 0.2025 0.2003
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.016 0.1875
Loa Loa (eye worm) hypothetical protein 0.011 0.2025 0.4114
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0032 0.0428 0.7969
Echinococcus granulosus solute carrier family 22 0.0015 0.0075 0.0047
Giardia lamblia Prolyl-tRNA synthetase 0.0032 0.042 0.7735
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.0051 0.0811 0.0785
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0024 0.0253 0.1157
Echinococcus multilocularis glycine receptor subunit alpha 1 0.011 0.2025 0.2003
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0106 0.1933 0.1911
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0134 0.2517 0.2496
Loa Loa (eye worm) hypothetical protein 0.0015 0.0075 0.0117
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.0051 0.0811 0.1559
Mycobacterium ulcerans aldehyde dehydrogenase 0.0118 0.2191 1
Echinococcus granulosus glycine receptor subunit alpha 1 0.011 0.2025 0.2003
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0036 0.0503 0.9602
Echinococcus granulosus dna polymerase kappa 0.0019 0.016 0.0132
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0032 0.0428 0.1668
Chlamydia trachomatis lysine--tRNA ligase 0.0024 0.0253 1
Onchocerca volvulus 0.0036 0.0496 0.0874
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0051 0.0811 0.1559
Plasmodium vivax hypothetical protein, conserved 0.0036 0.0496 0.0475
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.011 0.2025 0.4068
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0037 0.052 0.437
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.016 0.0214
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0037 0.0527 1
Loa Loa (eye worm) hypothetical protein 0.0032 0.042 0.0823
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0503 0.2303
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0036 0.0503 0.0737
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.016 0.2472
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0015 0.0084 0.0056
Loa Loa (eye worm) inositol-1 0.0036 0.0503 0.0994
Loa Loa (eye worm) hypothetical protein 0.0051 0.0811 0.1625
Loa Loa (eye worm) hypothetical protein 0.0015 0.0075 0.0117
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.0051 0.0811 0.1559
Onchocerca volvulus 0.011 0.2025 0.4044
Onchocerca volvulus 0.0036 0.0496 0.0874
Echinococcus multilocularis dna polymerase eta 0.0019 0.016 0.0132
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.0015 0.0075 0.0342
Schistosoma mansoni serine/threonine protein kinase 0.0032 0.0433 0.0361
Schistosoma mansoni intermediate filament proteins 0.0026 0.0303 0.023
Brugia malayi Cation transporter family protein 0.011 0.2025 0.4068
Brugia malayi hypothetical protein 0.0051 0.0811 0.1559

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.