Detailed information for compound 656257

Basic information

Technical information
  • TDR Targets ID: 656257
  • Name: 4-bromo-3-[(4-methoxyphenyl)sulfamoyl]-N-phen ylbenzamide
  • MW: 461.329 | Formula: C20H17BrN2O4S
  • H donors: 2 H acceptors: 3 LogP: 3.94 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1ccc(cc1)NS(=O)(=O)c1cc(ccc1Br)C(=O)Nc1ccccc1
  • InChi: 1S/C20H17BrN2O4S/c1-27-17-10-8-16(9-11-17)23-28(25,26)19-13-14(7-12-18(19)21)20(24)22-15-5-3-2-4-6-15/h2-13,23H,1H3,(H,22,24)
  • InChiKey: PORPROATIZNOPT-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 4-bromo-3-[(4-methoxyphenyl)sulfamoyl]-N-phenyl-benzamide
  • EU-0034694
  • 4-Bromo-3-(4-methoxy-phenylsulfamoyl)-N-phenyl-benzamide
  • BAS 00604161
  • ZINC00866152

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0048 0.0582 1
Loa Loa (eye worm) thioredoxin reductase 0.0139 0.2077 0.5571
Trypanosoma cruzi hypothetical protein, conserved 0.0033 0.0325 0.1562
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0048 0.0582 0.2803
Loa Loa (eye worm) nuclear hormone receptor 0.0014 0.0016 0.0044
Echinococcus multilocularis muscleblind protein 1 0.0134 0.2 0.2
Loa Loa (eye worm) DR-78 0.0014 0.0016 0.0044
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0048 0.0582 0.2803
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0018 0.0094 0.161
Loa Loa (eye worm) steroid hormone receptor 0.0029 0.027 0.0725
Schistosoma mansoni patched 1 0.0048 0.0584 0.0584
Echinococcus multilocularis microtubule associated protein 2 0.0621 1 1
Brugia malayi nuclear receptor NHR-67 0.0014 0.0016 0.0044
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0029 0.027 0.0725
Entamoeba histolytica hypothetical protein 0.0079 0.1089 0.6638
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0029 0.027 0.027
Echinococcus multilocularis GPCR, family 2 0.0017 0.0063 0.0063
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0048 0.0582 0.0582
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0353 0.559 1
Brugia malayi Muscleblind-like protein 0.0134 0.2 0.5364
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0033 0.0325 0.5557
Brugia malayi nuclear hormone receptor 0.0029 0.027 0.0725
Brugia malayi hypothetical protein 0.0014 0.0016 0.0044
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0029 0.027 0.0725
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0019 0.0096 0.0172
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0029 0.027 0.027
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0029 0.027 0.027
Loa Loa (eye worm) hypothetical protein 0.0015 0.0044 0.0117
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0017 0.0063 0.0063
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0048 0.0582 0.0582
Schistosoma mansoni steroid hormone receptor ad4bp 0.0029 0.027 0.027
Brugia malayi conserved hypotetical protein 0.0014 0.0016 0.0044
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0041 0.0461 0.0825
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0029 0.027 0.0725
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.008 0.0142
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0018 0.0094 0.0451
Brugia malayi Isocitrate dehydrogenase 0.0014 0.0023 0.0063
Toxoplasma gondii histone lysine methyltransferase SET1 0.0057 0.0732 0.3523
Trypanosoma cruzi hypothetical protein, conserved 0.0041 0.0461 0.2221
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.02 0.3437
Mycobacterium tuberculosis Probable hydrolase 0.0041 0.0461 0.0825
Mycobacterium leprae conserved hypothetical protein 0.0041 0.0461 0.0825
Loa Loa (eye worm) hypothetical protein 0.0015 0.0044 0.0117
Loa Loa (eye worm) hypothetical protein 0.0014 0.0016 0.0044
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0014 0.0016 0.0016
Schistosoma mansoni nuclear hormone receptor 0.0029 0.027 0.027
Mycobacterium tuberculosis Conserved protein 0.0041 0.0461 0.0825
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0029 0.027 0.0725
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0048 0.0582 0.2803
Loa Loa (eye worm) hypothetical protein 0.0014 0.0016 0.0044
Echinococcus granulosus FTZ F1 alpha 0.0029 0.027 0.027
Schistosoma mansoni zinc finger protein 0.0014 0.0016 0.0016
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0029 0.027 0.0725
Brugia malayi MH2 domain containing protein 0.0126 0.1857 0.498
Schistosoma mansoni hypothetical protein 0.0047 0.0555 0.0555
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0018 0.0094 0.0251
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0014 0.0023 0.0023
Mycobacterium ulcerans lipase LipD 0.0041 0.0461 0.7922
Echinococcus multilocularis expressed conserved protein 0.0106 0.1528 0.1528
Onchocerca volvulus 0.0041 0.0461 0.2278
Echinococcus multilocularis sterol regulatory element binding protein 0.0048 0.0584 0.0584
Onchocerca volvulus Bile acid receptor homolog 0.0029 0.027 0.1335
Brugia malayi tailless protein 0.0014 0.0016 0.0044
Echinococcus granulosus neuropeptide receptor A26 0.042 0.6702 0.6702
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0025 0.02 0.0358
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0029 0.027 0.027
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0029 0.027 0.0725
Schistosoma mansoni transcription factor LCR-F1 0.0079 0.1089 0.1089
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0018 0.0094 0.161
Echinococcus granulosus ecdysone induced protein 78C 0.0029 0.027 0.027
Echinococcus multilocularis neuropeptide receptor A26 0.042 0.6702 0.6702
Brugia malayi AMP-binding enzyme family protein 0.0025 0.02 0.0537
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0041 0.0461 0.0461
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0025 0.02 0.3437
Schistosoma mansoni ap endonuclease 0.0018 0.0094 0.0094
Loa Loa (eye worm) hypothetical protein 0.0014 0.0016 0.0044
Loa Loa (eye worm) hypothetical protein 0.0014 0.0016 0.0044
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0014 0.0023 0.0112
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0029 0.027 0.0725
Onchocerca volvulus 0.0014 0.0016 0.0081
Brugia malayi hypothetical protein 0.0049 0.0599 0.1607
Entamoeba histolytica acyl-CoA synthetase, putative 0.0025 0.02 0.122
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0014 0.0016 0.0016
Plasmodium falciparum ataxin-2 like protein, putative 0.0049 0.0599 0.2884
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0048 0.0582 0.0582
Trichomonas vaginalis alpha-glucosidase, putative 0.0033 0.0325 0.5557
Plasmodium falciparum glutathione reductase 0.0048 0.0582 0.2803
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0353 0.559 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0029 0.027 0.0725
Echinococcus multilocularis isocitrate dehydrogenase 0.0014 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0014 0.0016 0.0044
Brugia malayi map kinase activated protein kinase protein 2 0.024 0.3728 1
Loa Loa (eye worm) hypothetical protein 0.0017 0.0063 0.0168
Brugia malayi ecdysone receptor 0.0014 0.0016 0.0044
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.008 0.0142
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0025 0.02 0.3437
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0041 0.0461 0.1237
Mycobacterium tuberculosis Probable esterase LipL 0.0041 0.0461 0.0825
Mycobacterium tuberculosis Probable reductase 0.0317 0.5008 0.8958
Trypanosoma cruzi hypothetical protein, conserved 0.0041 0.0461 0.2221
Echinococcus granulosus mitogen activated protein kinase 11 0.0086 0.1209 0.1209
Brugia malayi hypothetical protein 0.0015 0.0044 0.0117
Brugia malayi hypothetical protein 0.0032 0.0312 0.0837
Schistosoma mansoni hypothetical protein 0.0017 0.0063 0.0063
Schistosoma mansoni cpg binding protein 0.0032 0.0315 0.0315
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0029 0.027 0.027
Loa Loa (eye worm) hypothetical protein 0.0019 0.0096 0.0258
Brugia malayi glutathione reductase 0.0139 0.2077 0.5571
Echinococcus multilocularis lysosomal alpha glucosidase 0.0147 0.22 0.22
Brugia malayi nuclear receptor NHR-88 0.0014 0.0016 0.0044
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0048 0.0582 1
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0029 0.027 0.027
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0029 0.027 0.0725
Loa Loa (eye worm) glutathione reductase 0.0139 0.2077 0.5571
Treponema pallidum NADH oxidase 0.0048 0.0582 1
Echinococcus granulosus mitogen activated protein kinase 14 0.0086 0.1209 0.1209
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0029 0.027 0.0725
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0014 0.0023 0.0023
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0014 0.0023 0.0023
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0048 0.0582 0.0582
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0048 0.0582 1
Echinococcus granulosus tumor protein p63 0.0352 0.5579 0.5579
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0014 0.0023 0.0042
Mycobacterium ulcerans hypothetical protein 0.0025 0.02 0.3437
Brugia malayi hypothetical protein 0.011 0.1602 0.4297
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.02 0.3437
Giardia lamblia NADH oxidase lateral transfer candidate 0.0048 0.0582 1
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0014 0.0016 0.0081
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0079 0.1089 0.1089
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0015 0.0044 0.0117
Leishmania major hypothetical protein, conserved 0.0041 0.0461 0.2221
Brugia malayi Glycosyl hydrolases family 31 protein 0.0033 0.0325 0.087
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0029 0.027 0.0725
Brugia malayi Nuclear hormone receptor E75 0.0014 0.0016 0.0044
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0317 0.5008 0.8958
Treponema pallidum exodeoxyribonuclease (exoA) 0.0018 0.0094 0.161
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0048 0.0582 0.2803
Mycobacterium tuberculosis Probable lipase LipD 0.0041 0.0461 0.0825
Loa Loa (eye worm) hypothetical protein 0.0049 0.0599 0.1607
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0029 0.027 0.027
Trichomonas vaginalis alpha-glucosidase, putative 0.0033 0.0325 0.5557
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0014 0.0023 0.0023
Trichomonas vaginalis maltase-glucoamylase, putative 0.0033 0.0325 0.5557
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0014 0.0023 0.0023
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0114 0.1669 0.1669
Brugia malayi ecdysteroid receptor 0.0029 0.027 0.0725
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0018 0.0094 0.161
Schistosoma mansoni cpg binding protein 0.003 0.0287 0.0287
Brugia malayi AMP-binding enzyme family protein 0.0025 0.02 0.0537
Loa Loa (eye worm) hypothetical protein 0.0134 0.2 0.5364
Plasmodium vivax thioredoxin reductase, putative 0.0139 0.2077 1
Schistosoma mansoni hypothetical protein 0.0017 0.0063 0.0063
Mycobacterium tuberculosis Probable lipase LipE 0.0041 0.0461 0.0825
Loa Loa (eye worm) hypothetical protein 0.011 0.1602 0.4297
Trichomonas vaginalis sucrase-isomaltase, putative 0.0033 0.0325 0.5557
Onchocerca volvulus Huntingtin homolog 0.011 0.1602 0.7911
Brugia malayi latrophilin 2 splice variant baaae 0.0036 0.038 0.1018
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0022 0.0153 0.0153
Echinococcus granulosus dnaJ subfamily B 0.0431 0.6873 0.6873
Brugia malayi nuclear receptor RXR 0.0014 0.0016 0.0044
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0086 0.1209 0.5822
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0029 0.027 0.027
Trypanosoma brucei trypanothione reductase 0.0139 0.2077 1
Schistosoma mansoni hypothetical protein 0.0047 0.0555 0.0555
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0014 0.0023 0.0023
Brugia malayi CHE-14 protein 0.0048 0.0584 0.1566
Onchocerca volvulus Protein ultraspiracle homolog 0.0029 0.027 0.1335
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0029 0.027 0.027
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.0094 0.1606
Entamoeba histolytica hypothetical protein 0.0079 0.1089 0.6638
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.0094 0.0451
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0014 0.0023 0.0112
Echinococcus multilocularis nuclear receptor nhr 48 0.0014 0.0016 0.0016
Trichomonas vaginalis mercuric reductase, putative 0.0048 0.0582 0.9973
Schistosoma mansoni hypothetical protein 0.0036 0.038 0.038
Trichomonas vaginalis penicillin-binding protein, putative 0.0041 0.0461 0.7901
Echinococcus multilocularis cpg binding protein 0.0032 0.0315 0.0315
Brugia malayi Nuclear hormone receptor-like 1 0.0015 0.0044 0.0117
Loa Loa (eye worm) hypothetical protein 0.0052 0.0637 0.1708
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0033 0.0325 0.5557
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0048 0.0582 0.2803
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0015 0.0044 0.0044
Plasmodium falciparum thioredoxin reductase 0.0139 0.2077 1
Loa Loa (eye worm) hypothetical protein 0.0059 0.0763 0.2045
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0086 0.1209 0.5822
Echinococcus multilocularis tumor protein p63 0.0352 0.5579 0.5579
Loa Loa (eye worm) hypothetical protein 0.0041 0.0461 0.1237
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0029 0.027 0.0725
Schistosoma mansoni alpha glucosidase 0.0033 0.0325 0.0325
Echinococcus multilocularis geminin 0.0177 0.2693 0.2693
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0029 0.027 0.027
Plasmodium falciparum thioredoxin reductase 0.0048 0.0582 0.2803
Brugia malayi beta-lactamase 0.0041 0.0461 0.1237
Echinococcus granulosus thioredoxin glutathione reductase 0.014 0.2087 0.2087
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0048 0.0582 0.2803
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0041 0.0461 0.1237
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0079 0.1089 0.1089
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0052 0.0653 0.1751
Echinococcus multilocularis beta LACTamase domain containing family member 0.0041 0.0461 0.0461
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0139 0.2077 0.3716
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0018 0.0094 0.0451
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0048 0.0582 0.2803
Entamoeba histolytica hypothetical protein 0.0079 0.1089 0.6638
Loa Loa (eye worm) hypothetical protein 0.0019 0.0096 0.0258
Echinococcus multilocularis mitogen activated protein kinase 14 0.0086 0.1209 0.1209
Brugia malayi Glycosyl hydrolases family 31 protein 0.0147 0.22 0.5901
Loa Loa (eye worm) hypothetical protein 0.0052 0.0653 0.1751
Plasmodium vivax acyl-CoA synthetase, putative 0.0019 0.0096 0.0464
Brugia malayi photoreceptor-specific nuclear receptor 0.0029 0.027 0.0725
Schistosoma mansoni thyroid hormone receptor 0.0029 0.027 0.027
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0048 0.0582 0.2803
Loa Loa (eye worm) hypothetical protein 0.0136 0.2025 0.5432
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0017 0.0063 0.0063
Echinococcus multilocularis neuropeptide s receptor 0.042 0.6702 0.6702
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0048 0.0582 0.2803
Schistosoma mansoni nuclear hormone receptor 0.0014 0.0016 0.0016
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0048 0.0582 0.2803
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0582 0.0582
Toxoplasma gondii ABC1 family protein 0.0041 0.0461 0.2221
Entamoeba histolytica acyl-CoA synthetase, putative 0.0025 0.02 0.122
Mycobacterium tuberculosis Conserved protein 0.0041 0.0461 0.0825
Schistosoma mansoni nuclear hormone receptor 0.0014 0.0016 0.0016
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0317 0.5008 0.8958
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.0094 0.0451
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0048 0.0582 0.2803
Loa Loa (eye worm) hypothetical protein 0.0014 0.0016 0.0044
Schistosoma mansoni hypothetical protein 0.0017 0.0063 0.0063
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0029 0.027 0.027
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0048 0.0582 1
Schistosoma mansoni cellular tumor antigen P53 0.0052 0.0637 0.0637
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0029 0.027 0.027
Echinococcus granulosus Niemann Pick C1 protein 0.0113 0.1641 0.1641
Brugia malayi exodeoxyribonuclease III family protein 0.0018 0.0094 0.0251
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0014 0.0023 0.0112
Echinococcus multilocularis thioredoxin glutathione reductase 0.014 0.2087 0.2087
Schistosoma mansoni hypothetical protein 0.0079 0.1089 0.1089
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.024 0.3728 0.3728
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.02 0.0964
Loa Loa (eye worm) beta-lactamase 0.0041 0.0461 0.1237
Plasmodium falciparum acyl-CoA synthetase 0.0019 0.0096 0.0464
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0317 0.5008 0.8958
Echinococcus multilocularis mitogen activated protein kinase 11 0.0086 0.1209 0.1209
Echinococcus granulosus Protein patched homolog 1 0.0048 0.0584 0.0584
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0025 0.02 0.3437
Echinococcus granulosus GPCR family 2 0.0017 0.0063 0.0063
Echinococcus granulosus lysosomal alpha glucosidase 0.0147 0.22 0.22
Loa Loa (eye worm) MH2 domain-containing protein 0.0126 0.1857 0.498
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0019 0.0096 0.1655
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0029 0.027 0.0725
Schistosoma mansoni thyroid hormone receptor 0.0029 0.027 0.027
Brugia malayi hypothetical protein 0.0014 0.0016 0.0044
Loa Loa (eye worm) hypothetical protein 0.0029 0.027 0.0725
Mycobacterium leprae Probable lipase LipE 0.0041 0.0461 0.0825
Entamoeba histolytica hypothetical protein 0.0079 0.1089 0.6638
Brugia malayi Niemann-Pick C1 protein precursor 0.0113 0.1641 0.44
Brugia malayi hypothetical protein 0.0079 0.1089 0.2921
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0014 0.0023 0.0112
Trichomonas vaginalis alpha-glucosidase, putative 0.0033 0.0325 0.5557
Leishmania major hypothetical protein, conserved 0.0049 0.0599 0.2884
Onchocerca volvulus 0.0029 0.027 0.1335
Loa Loa (eye worm) hypothetical protein 0.0041 0.0461 0.1237
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0018 0.0094 0.0451
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0029 0.027 0.027
Brugia malayi nuclear receptor RXR 0.0015 0.0044 0.0117
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0029 0.027 0.1335
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0014 0.0023 0.0112
Loa Loa (eye worm) hypothetical protein 0.0113 0.1641 0.44
Brugia malayi Nuclear hormone receptor-like 1 0.0029 0.027 0.0725
Echinococcus granulosus thyroid hormone receptor alpha 0.0014 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0029 0.027 0.0725
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0048 0.0582 0.2803
Brugia malayi Nuclear hormone receptor-like 1 0.0015 0.0044 0.0117
Schistosoma mansoni hypothetical protein 0.0022 0.0153 0.0153
Brugia malayi AMP-binding enzyme family protein 0.0025 0.02 0.0537
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0018 0.0094 0.0168
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0014 0.0023 0.0112
Trypanosoma cruzi PAB1-binding protein , putative 0.0049 0.0599 0.2884
Mycobacterium tuberculosis Conserved protein 0.0041 0.0461 0.0825
Entamoeba histolytica acyl-coA synthetase, putative 0.0025 0.02 0.122
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0018 0.0094 0.0094
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0029 0.027 0.027
Onchocerca volvulus 0.0085 0.1184 0.5845
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0025 0.02 0.0358
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0017 0.0063 0.0063
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0018 0.0094 0.0572
Echinococcus multilocularis Niemann Pick C1 protein 0.0113 0.1641 0.1641
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0029 0.027 0.0725
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0014 0.0016 0.0016
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0048 0.0582 0.2803
Echinococcus multilocularis neutral alpha glucosidase AB 0.0033 0.0325 0.0325
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0048 0.0582 0.1562
Trichomonas vaginalis alpha-glucosidase, putative 0.0033 0.0325 0.5557
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0041 0.0461 0.0825
Echinococcus multilocularis thyroid hormone receptor alpha 0.0029 0.027 0.027
Loa Loa (eye worm) hypothetical protein 0.0029 0.027 0.0725
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0014 0.0016 0.0016
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0014 0.0016 0.0016
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0014 0.0016 0.0044
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0014 0.0016 0.0016
Schistosoma mansoni retinoic acid receptor RXR 0.0029 0.027 0.027
Loa Loa (eye worm) hypothetical protein 0.011 0.1602 0.4297
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0015 0.0044 0.0044
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0033 0.0325 0.087
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0018 0.0094 0.0094
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0014 0.0016 0.0016
Plasmodium falciparum ataxin-2 like protein, putative 0.0049 0.0599 0.2884
Brugia malayi beta-lactamase family protein 0.0041 0.0461 0.1237
Toxoplasma gondii LsmAD domain-containing protein 0.0049 0.0599 0.2884
Echinococcus granulosus geminin 0.0177 0.2693 0.2693
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0086 0.1209 0.5822
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0582 0.0582
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0064 0.0844 0.0844
Brugia malayi Steroid receptor seven-up type 2 0.0029 0.027 0.0725
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0029 0.027 0.027
Schistosoma mansoni RAR-like nuclear receptor 0.0029 0.027 0.027
Loa Loa (eye worm) hypothetical protein 0.0029 0.027 0.0725
Echinococcus multilocularis muscleblind protein 0.0134 0.2 0.2
Echinococcus multilocularis mitogen activated protein kinase 14 0.0086 0.1209 0.1209
Schistosoma mansoni nuclear receptor nhr-48 0.0014 0.0016 0.0016
Trypanosoma cruzi trypanothione reductase, putative 0.0048 0.0582 0.2803
Loa Loa (eye worm) hypothetical protein 0.0015 0.0044 0.0117
Loa Loa (eye worm) hypothetical protein 0.0029 0.027 0.0725
Plasmodium falciparum glutathione reductase 0.0139 0.2077 1
Brugia malayi nuclear receptor NHR-88 0.0029 0.027 0.0725
Plasmodium vivax glutathione reductase, putative 0.0139 0.2077 1
Mycobacterium ulcerans beta-lactamase 0.0041 0.0461 0.7922
Schistosoma mansoni serine/threonine protein kinase 0.024 0.3728 0.3728
Trypanosoma brucei hypothetical protein, conserved 0.0041 0.0461 0.2221
Schistosoma mansoni hypothetical protein 0.0047 0.0555 0.0555
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0086 0.1209 0.5822
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0041 0.0461 0.7922
Loa Loa (eye worm) nuclear receptor NHR-67 0.0014 0.0016 0.0044
Loa Loa (eye worm) hypothetical protein 0.0029 0.027 0.0725
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0029 0.027 0.027
Schistosoma mansoni alpha-glucosidase 0.0126 0.1865 0.1865
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0113 0.1641 1
Schistosoma mansoni hypothetical protein 0.0047 0.0555 0.0555
Brugia malayi Calcitonin receptor-like protein seb-1 0.0052 0.0653 0.1751
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0048 0.0582 0.156
Brugia malayi beta-lactamase family protein 0.0041 0.0461 0.1237
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0025 0.02 0.0358
Brugia malayi Nuclear hormone receptor E75 0.0014 0.0016 0.0044
Loa Loa (eye worm) hypothetical protein 0.0025 0.02 0.0537
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0025 0.02 0.0358
Mycobacterium tuberculosis Probable oxidoreductase 0.0353 0.559 1
Schistosoma mansoni nuclear receptor 0.0014 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0019 0.0096 0.0258
Brugia malayi isocitrate dehydrogenase 0.0014 0.0023 0.0063
Loa Loa (eye worm) hypothetical protein 0.0014 0.0016 0.0044
Loa Loa (eye worm) hypothetical protein 0.0014 0.0016 0.0044
Echinococcus granulosus beta LACTamase domain containing family member 0.0041 0.0461 0.0461
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.008 0.0142
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0086 0.1209 0.3244
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0041 0.0461 0.0825
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.02 0.3437
Trichomonas vaginalis esterase, putative 0.0041 0.0461 0.7901
Echinococcus granulosus Niemann Pick C1 protein 0.0161 0.2435 0.2435
Echinococcus multilocularis Niemann Pick C1 protein 0.0161 0.2435 0.2435
Schistosoma mansoni cpg binding protein 0.0032 0.0315 0.0315
Trichomonas vaginalis D-aminoacylase, putative 0.0041 0.0461 0.7901
Schistosoma mansoni hypothetical protein 0.0177 0.2693 0.2693
Schistosoma mansoni hypothetical protein 0.0177 0.2693 0.2693
Loa Loa (eye worm) hypothetical protein 0.0048 0.0584 0.1566
Echinococcus granulosus Nuclear hormone receptor HR96 0.0014 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0019 0.0096 0.0258
Onchocerca volvulus 0.0041 0.0461 0.2278
Loa Loa (eye worm) hypothetical protein 0.0029 0.027 0.0725
Brugia malayi orphan nuclear receptor NR2E1 0.0014 0.0016 0.0044
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0048 0.0582 0.0582
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0048 0.0582 0.2803
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0029 0.027 0.027
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0014 0.0016 0.0016
Echinococcus granulosus MAP kinase activated protein kinase 2 0.024 0.3728 0.3728
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0048 0.0582 0.0582
Onchocerca volvulus 0.0014 0.0016 0.0081
Trichomonas vaginalis alpha-glucosidase, putative 0.0033 0.0325 0.5557
Loa Loa (eye worm) hypothetical protein 0.0014 0.0016 0.0044
Echinococcus multilocularis protein dispatched 1 0.0055 0.0696 0.0696
Echinococcus granulosus Nuclear hormone receptor HR96 0.0014 0.0016 0.0016
Mycobacterium ulcerans hypothetical protein 0.0041 0.0461 0.7922
Trypanosoma brucei glucosidase, putative 0.0033 0.0325 0.1562
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0029 0.027 0.0725
Loa Loa (eye worm) hypothetical protein 0.0036 0.038 0.1018
Loa Loa (eye worm) hypothetical protein 0.0041 0.0461 0.1237
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0052 0.0653 0.1751
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0041 0.0461 0.0461
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.0094 0.1606
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0018 0.0094 0.0451
Loa Loa (eye worm) transcription factor SMAD2 0.0126 0.1857 0.498
Loa Loa (eye worm) hypothetical protein 0.0014 0.0016 0.0044
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0022 0.0153 0.0153
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0353 0.559 1
Echinococcus multilocularis ecdysone induced protein 78C 0.0029 0.027 0.027
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0019 0.0096 0.1655
Trypanosoma brucei PAB1-binding protein , putative 0.0049 0.0599 0.2884
Schistosoma mansoni microtubule-associated protein tau 0.0621 1 1
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0029 0.027 0.0725
Loa Loa (eye worm) hypothetical protein 0.0041 0.0461 0.1237
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0035 0.0372 0.0997
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0017 0.0063 0.0168
Onchocerca volvulus 0.003 0.0287 0.1417
Brugia malayi hypothetical protein 0.0015 0.0044 0.0117
Brugia malayi hypothetical protein 0.0136 0.2025 0.5432
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0025 0.02 0.3437
Echinococcus multilocularis lysosomal alpha glucosidase 0.0147 0.22 0.22
Loa Loa (eye worm) hypothetical protein 0.0041 0.0461 0.1237
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0048 0.0582 0.2803
Mycobacterium tuberculosis Probable dehydrogenase 0.0317 0.5008 0.8958
Onchocerca volvulus 0.0025 0.02 0.0988
Loa Loa (eye worm) hypothetical protein 0.0015 0.0044 0.0117
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.008 0.0142
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0014 0.0023 0.0112
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0014 0.0016 0.0016
Toxoplasma gondii NADPH-glutathione reductase 0.0048 0.0582 0.2803
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.024 0.3728 1
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0048 0.0582 0.2803
Loa Loa (eye worm) hypothetical protein 0.0014 0.0016 0.0044
Brugia malayi nuclear hormone receptor family member nhr-6 0.0014 0.0016 0.0044
Schistosoma mansoni alpha-glucosidase 0.0126 0.1865 0.1865
Trypanosoma cruzi PAB1-binding protein , putative 0.0049 0.0599 0.2884
Leishmania major trypanothione reductase 0.0139 0.2077 1
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0035 0.0372 0.0997
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0048 0.0582 0.1042
Trypanosoma cruzi hypothetical protein, conserved 0.0033 0.0325 0.1562
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0029 0.027 0.0725
Brugia malayi Thioredoxin reductase 0.0139 0.2077 0.5571
Brugia malayi Latrophilin receptor protein 2 0.0017 0.0063 0.0168
Trichomonas vaginalis glutathione reductase, putative 0.0048 0.0582 0.9973
Brugia malayi P38 map kinase family protein 2 0.0086 0.1209 0.3244
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0048 0.0582 0.156
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0317 0.5008 0.8958
Echinococcus multilocularis mitogen activated protein kinase 11 0.0086 0.1209 0.1209
Trichomonas vaginalis D-aminoacylase, putative 0.0041 0.0461 0.7901
Loa Loa (eye worm) CXXC zinc finger family protein 0.003 0.0287 0.077
Plasmodium vivax hypothetical protein, conserved 0.0041 0.0461 0.2221
Onchocerca volvulus 0.0052 0.0637 0.3145
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0048 0.0582 0.0582
Onchocerca volvulus 0.0041 0.0461 0.2278
Trichomonas vaginalis penicillin-binding protein, putative 0.0041 0.0461 0.7901
Echinococcus multilocularis FTZ F1 alpha 0.0029 0.027 0.027
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0029 0.027 0.0725
Loa Loa (eye worm) hypothetical protein 0.0015 0.0044 0.0117
Echinococcus granulosus cpg binding protein 0.0032 0.0315 0.0315
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0048 0.0582 0.2803
Schistosoma mansoni coup transcription factor 0.0029 0.027 0.027
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0317 0.5008 0.8958
Loa Loa (eye worm) hypothetical protein 0.0025 0.02 0.0537
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.02 0.0964
Schistosoma mansoni nuclear receptor 0.0014 0.0016 0.0016
Brugia malayi nuclear hormone receptor family member odr-7 0.0014 0.0016 0.0044
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0015 0.0044 0.0044
Loa Loa (eye worm) hypothetical protein 0.0029 0.027 0.0725
Echinococcus granulosus nuclear receptor nhr 48 0.0014 0.0016 0.0016
Schistosoma mansoni hypothetical protein 0.0017 0.0063 0.0063
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0261 0.4081 0.7301
Toxoplasma gondii thioredoxin reductase 0.0139 0.2077 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0582 0.0582
Plasmodium vivax ataxin-2 like protein, putative 0.0049 0.0599 0.2884
Leishmania major alpha glucosidase II subunit, putative 0.0033 0.0325 0.1562
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0033 0.0325 0.1978
Onchocerca volvulus Huntingtin homolog 0.011 0.1602 0.7911
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0048 0.0582 1
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0584 1
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0048 0.0582 0.2803
Echinococcus multilocularis dnaJ subfamily B 0.0431 0.6873 0.6873
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0048 0.0582 1
Echinococcus granulosus sterol regulatory element binding protein 0.0048 0.0584 0.0584
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0015 0.0044 0.0044
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.02 0.0964
Mycobacterium ulcerans esterase/lipase LipP 0.0041 0.0461 0.7922
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0029 0.027 0.0725
Echinococcus granulosus expressed conserved protein 0.0106 0.1528 0.1528
Loa Loa (eye worm) hypothetical protein 0.0134 0.2 0.5364
Brugia malayi CXXC zinc finger family protein 0.003 0.0287 0.077
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0048 0.0582 0.2803
Trypanosoma cruzi trypanothione reductase, putative 0.0139 0.2077 1
Loa Loa (eye worm) hypothetical protein 0.0014 0.0016 0.0044
Trichomonas vaginalis D-aminoacylase, putative 0.0041 0.0461 0.7901
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0048 0.0582 0.2803
Schistosoma mansoni ap endonuclease 0.0018 0.0094 0.0094
Brugia malayi nuclear hormone receptor 0.0014 0.0016 0.0044
Toxoplasma gondii isocitrate dehydrogenase 0.0014 0.0023 0.0112
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0029 0.027 0.0725
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0147 0.22 0.5901
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0033 0.0325 0.1978
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0048 0.0584 0.1566
Echinococcus multilocularis protein patched 0.0048 0.0584 0.0584
Loa Loa (eye worm) hypothetical protein 0.0041 0.0461 0.1237
Brugia malayi steroid hormone receptor 0.0029 0.027 0.0725
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0029 0.027 0.027
Toxoplasma gondii isocitrate dehydrogenase 0.0014 0.0023 0.0112
Loa Loa (eye worm) isocitrate dehydrogenase 0.0014 0.0023 0.0063
Echinococcus granulosus muscleblind protein 0.0134 0.2 0.2
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0014 0.0016 0.0044
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0033 0.0325 0.1562
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0048 0.0582 0.2803
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0014 0.0016 0.0081
Onchocerca volvulus 0.0136 0.2025 1
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0029 0.027 0.027
Echinococcus granulosus neuropeptide s receptor 0.042 0.6702 0.6702
Loa Loa (eye worm) latrophilin receptor protein 2 0.0017 0.0063 0.0168
Echinococcus granulosus neutral alpha glucosidase AB 0.0033 0.0325 0.0325
Loa Loa (eye worm) hypothetical protein 0.0025 0.02 0.0537
Toxoplasma gondii exonuclease III APE 0.0018 0.0094 0.0451
Schistosoma mansoni hypothetical protein 0.0431 0.6873 0.6873
Loa Loa (eye worm) hypothetical protein 0.0019 0.0096 0.0258
Loa Loa (eye worm) hypothetical protein 0.0014 0.0016 0.0044
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0017 0.0063 0.0063

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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