Detailed information for compound 663803

Basic information

Technical information
  • TDR Targets ID: 663803
  • Name: ZINC01136427
  • MW: 414.905 | Formula: C21H19ClN2O3S
  • H donors: 2 H acceptors: 3 LogP: 4.64 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: Cc1cccc(c1)NC(=O)c1cc(ccc1Cl)S(=O)(=O)Nc1cccc(c1)C
  • InChi: 1S/C21H19ClN2O3S/c1-14-5-3-7-16(11-14)23-21(25)19-13-18(9-10-20(19)22)28(26,27)24-17-8-4-6-15(2)12-17/h3-13,24H,1-2H3,(H,23,25)
  • InChiKey: RCNGTTRRNVYROS-UHFFFAOYSA-N  


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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0017 0.0116 0.2572
Echinococcus multilocularis solute carrier family 22 0.003 0.0254 0.0285
Schistosoma mansoni thyroid hormone receptor 0.001 0.0032 0.0042
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.001 0.0032 0.0042
Echinococcus multilocularis Sugar transporter ERD6 protein 0.003 0.0254 0.0285
Onchocerca volvulus 0.003 0.0254 0.1786
Onchocerca volvulus 0.003 0.0254 0.1786
Brugia malayi ecdysteroid receptor 0.001 0.0032 0.0065
Echinococcus granulosus chromobox protein 2 0.0011 0.0046 0.0061
Toxoplasma gondii YbaK/proline-tRNA ligase associated domain-containing protein 0.0011 0.0038 0.0057
Echinococcus multilocularis musashi 0.0027 0.0218 0.0245
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0047 0.045 0.5996
Loa Loa (eye worm) hypothetical protein 0.0012 0.0053 0.016
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.003 0.0254 0.0336
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0065 0.0647 0.1946
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0016 0.0095 0.0125
Brugia malayi Nuclear hormone receptor family member nhr-25 0.001 0.0032 0.0065
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0182 0.0725
Loa Loa (eye worm) hypothetical protein 0.0012 0.0058 0.0175
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0303 0.3325 1
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0085 0.0368
Trypanosoma brucei glucose transporter 1E 0.0066 0.0656 0.8747
Mycobacterium ulcerans hypothetical protein 0.0011 0.0038 0.0841
Brugia malayi Calcitonin receptor-like protein seb-1 0.0049 0.0471 0.1995
Plasmodium vivax sugar transporter, putative 0.003 0.0254 0.0254
Entamoeba histolytica hypothetical protein 0.0023 0.0178 0.1768
Leishmania major threonyl-tRNA synthetase, putative 0.0012 0.0053 0.0711
Loa Loa (eye worm) hypothetical protein 0.0013 0.0064 0.0192
Mycobacterium leprae Probable lysyl-tRNA synthase LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.004 0.037 0.5587
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.004 0.037 1
Loa Loa (eye worm) helicase 0.0011 0.0046 0.0138
Wolbachia endosymbiont of Brugia malayi threonyl-tRNA synthetase 0.0012 0.0053 0.2103
Trichomonas vaginalis sugar transporter, putative 0.003 0.0254 0.1106
Brugia malayi threonyl-tRNA synthetase, cytoplasmic 0.0012 0.0053 0.0161
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0254 0.1106
Trypanosoma brucei glucose transporter, putative 0.0066 0.0656 0.8747
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.003 0.0254 0.5639
Echinococcus granulosus calcium dependent protein kinase 0.0061 0.0602 0.0797
Trichomonas vaginalis sugar transporter, putative 0.003 0.0254 0.1106
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0074 0.075 1
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0047 0.045 0.196
Trichomonas vaginalis sugar transporter, putative 0.003 0.0254 0.1106
Schistosoma mansoni glucose transport protein 0.0211 0.2295 0.3038
Schistosoma mansoni hypothetical protein 0.0011 0.0046 0.0061
Echinococcus multilocularis Threonyl tRNA synthetase, C 0.0012 0.0053 0.006
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0065 0.0647 0.8623
Brugia malayi Major Facilitator Superfamily protein 0.003 0.0254 0.104
Loa Loa (eye worm) latrophilin receptor protein 2 0.0016 0.0094 0.0283
Plasmodium falciparum calcium-dependent protein kinase 4 0.0065 0.0647 0.0647
Echinococcus granulosus solute carrier family 22 0.003 0.0254 0.0336
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0065 0.0647 0.2767
Echinococcus multilocularis chromobox protein 1 0.0069 0.0691 0.0777
Echinococcus granulosus geminin 0.0167 0.1794 0.2375
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0042 0.0387 0.1164
Echinococcus granulosus solute carrier family 22 0.003 0.0254 0.0336
Trichomonas vaginalis sugar transporter, putative 0.003 0.0254 0.1106
Echinococcus granulosus Sugar transporter ERD6 protein 0.003 0.0254 0.0336
Echinococcus granulosus ecdysone induced protein 78C 0.001 0.0032 0.0042
Schistosoma mansoni intermediate filament proteins 0.0027 0.0218 0.0289
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0211 0.2295 0.3038
Brugia malayi Niemann-Pick C1 protein precursor 0.0097 0.1009 0.4355
Loa Loa (eye worm) isocitrate dehydrogenase 0.0016 0.0095 0.0284
Trypanosoma brucei glucose transporter, putative 0.0066 0.0656 0.8747
Loa Loa (eye worm) hypothetical protein 0.003 0.0254 0.0763
Loa Loa (eye worm) hypothetical protein 0.0049 0.0467 0.1404
Schistosoma mansoni lysyl-tRNA synthetase 0.0047 0.045 0.0596
Echinococcus multilocularis cpg binding protein 0.003 0.0256 0.0287
Trichomonas vaginalis glucose transporter, putative 0.003 0.0254 0.1106
Brugia malayi lysyl-tRNA synthetase 0.0047 0.045 0.1901
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0016 0.0095 0.0106
Giardia lamblia Hexose transporter 0.003 0.0254 0.346
Echinococcus granulosus retinoic acid receptor rxr beta a 0.001 0.0032 0.0042
Trichomonas vaginalis hypothetical protein 0.0011 0.0046 0.02
Echinococcus granulosus Threonyl tRNA synthetase C 0.0012 0.0053 0.0071
Echinococcus granulosus Niemann Pick C1 protein 0.0097 0.1009 0.1336
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0254 0.1106
Trichomonas vaginalis sugar transporter, putative 0.003 0.0254 0.1106
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0047 0.045 0.5996
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.0095 0.0143
Loa Loa (eye worm) hypothetical protein 0.0097 0.1009 0.3034
Trypanosoma brucei threonyl-tRNA synthetase, putative 0.0012 0.0053 0.0711
Brugia malayi Nuclear hormone receptor family member nhr-3 0.001 0.0032 0.0065
Schistosoma mansoni sugar transporter 0.003 0.0254 0.0336
Plasmodium vivax glycine--tRNA ligase, putative 0.0012 0.0053 0.0053
Loa Loa (eye worm) hypothetical protein 0.0028 0.0239 0.0718
Schistosoma mansoni cpg binding protein 0.0028 0.0237 0.0314
Loa Loa (eye worm) hypothetical protein 0.001 0.0032 0.0095
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.001 0.0032 0.0095
Plasmodium falciparum protein kinase 7 0.0597 0.663 0.663
Echinococcus multilocularis Niemann Pick C1 protein 0.0138 0.1476 0.1661
Brugia malayi SET domain containing protein 0.0012 0.0053 0.0158
Onchocerca volvulus 0.003 0.0254 0.1786
Loa Loa (eye worm) hypothetical protein 0.001 0.0032 0.0095
Loa Loa (eye worm) steroid hormone receptor 0.001 0.0032 0.0095
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0118 0.0514
Leishmania major myo-inositol/proton symporter (MIT) 0.003 0.0254 0.3381
Trichomonas vaginalis sugar transporter, putative 0.003 0.0254 0.1106
Trypanosoma brucei ULK family serine/threonine-protein kinase, putative 0.0009 0.0025 0.034
Leishmania major lysyl-tRNA synthetase, putative 0.0047 0.045 0.5996
Schistosoma mansoni glucose transporter 0.003 0.0254 0.0336
Brugia malayi Sugar transporter family protein 0.003 0.0254 0.104
Plasmodium vivax heterochromatin protein 1, putative 0.0011 0.0046 0.0046
Schistosoma mansoni steroid hormone receptor ad4bp 0.001 0.0032 0.0042
Loa Loa (eye worm) hypothetical protein 0.003 0.0254 0.0763
Onchocerca volvulus 0.0049 0.0467 0.3501
Onchocerca volvulus Huntingtin homolog 0.0121 0.1275 1
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0065 0.0647 0.0856
Loa Loa (eye worm) hypothetical protein 0.003 0.0254 0.0763
Echinococcus multilocularis chromobox protein 1 0.0069 0.0691 0.0777
Toxoplasma gondii sugar transporter ST1 0.003 0.0254 0.0383
Brugia malayi Sugar transporter family protein 0.0211 0.2295 1
Brugia malayi Sugar transporter family protein 0.003 0.0254 0.104
Plasmodium vivax hypothetical protein, conserved 0.0011 0.0046 0.0046
Trichomonas vaginalis conserved hypothetical protein 0.0066 0.0656 0.286
Loa Loa (eye worm) sugar transporter 0.0211 0.2295 0.6901
Onchocerca volvulus 0.003 0.0254 0.1786
Giardia lamblia Prolyl-tRNA synthetase 0.0063 0.0632 1
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0016 0.0094 0.0125
Onchocerca volvulus 0.0028 0.0237 0.1656
Plasmodium falciparum proline--tRNA ligase 0.0074 0.075 0.075
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0211 0.2295 0.2581
Schistosoma mansoni hypothetical protein 0.0016 0.0094 0.0125
Schistosoma mansoni protein kinase 0.0065 0.0647 0.0856
Loa Loa (eye worm) hypothetical protein 0.0011 0.0046 0.0138
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.0095 0.0143
Schistosoma mansoni cpg binding protein 0.003 0.0256 0.0338
Leishmania major glucose transporter, lmgt3 0.0066 0.0656 0.8747
Brugia malayi intermediate filament protein 0.0027 0.0218 0.0884
Echinococcus multilocularis ecdysone induced protein 78C 0.001 0.0032 0.0035
Trypanosoma cruzi hexose transporter, putative 0.0066 0.0656 0.8747
Leishmania major hypothetical protein, conserved 0.0011 0.0038 0.0504
Echinococcus granulosus nuclear receptor 2DBD gamma 0.001 0.0032 0.0042
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0038 0.0352 0.2575
Echinococcus multilocularis solute carrier family 22 0.003 0.0254 0.0285
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0097 0.1009 1
Echinococcus granulosus GPCR family 2 0.0016 0.0094 0.0125
Loa Loa (eye worm) hypothetical protein 0.0121 0.1275 0.3835
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0798 0.8891 1
Echinococcus granulosus dnaJ subfamily B 0.0402 0.4445 0.5884
Onchocerca volvulus Huntingtin homolog 0.0121 0.1275 1
Trichomonas vaginalis sugar transporter, putative 0.003 0.0254 0.1106
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0237 0.0714
Echinococcus multilocularis sterol regulatory element binding protein 0.0042 0.0387 0.0435
Toxoplasma gondii facilitative glucose transporter GT1 0.0211 0.2295 0.3461
Trichomonas vaginalis sugar transporter, putative 0.003 0.0254 0.1106
Loa Loa (eye worm) hypothetical protein 0.003 0.0254 0.0763
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0013 0.0064 0.0085
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0011 0.0046 0.0061
Loa Loa (eye worm) hypothetical protein 0.001 0.0032 0.0095
Plasmodium falciparum calcium-dependent protein kinase 1 0.0065 0.0647 0.0647
Brugia malayi nuclear hormone receptor 0.001 0.0032 0.0065
Echinococcus multilocularis FTZ F1 alpha 0.001 0.0032 0.0035
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0015 0.0085 0.0368
Plasmodium vivax calcium-dependent protein kinase, putative 0.0065 0.0647 0.0647
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0074 0.075 1
Loa Loa (eye worm) hypothetical protein 0.0017 0.0116 0.0348
Loa Loa (eye worm) hypothetical protein 0.0051 0.0492 0.1481
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0118 0.0514
Toxoplasma gondii threonyl-tRNA synthetase family protein 0.0012 0.0053 0.008
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0095 0.126
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0038 0.0165
Plasmodium falciparum calcium-dependent protein kinase 3 0.0065 0.0647 0.0647
Schistosoma mansoni glycyl-tRNA synthetase 0.0012 0.0053 0.0071
Loa Loa (eye worm) hypothetical protein 0.0042 0.0387 0.1164
Loa Loa (eye worm) hypothetical protein 0.003 0.0254 0.0763
Schistosoma mansoni chromobox protein 0.0069 0.0691 0.0914
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0254 0.1106
Trichomonas vaginalis threonyl-tRNA synthetase, putative 0.0012 0.0053 0.0233
Schistosoma mansoni chromobox protein 0.0069 0.0691 0.0914
Brugia malayi probable proline-trna synthetase - fission yeast, putative 0.0012 0.0053 0.0161
Loa Loa (eye worm) hypothetical protein 0.0051 0.0499 0.15
Trypanosoma brucei sugar transporter, putative 0.003 0.0254 0.3381
Trichomonas vaginalis chromobox protein, putative 0.0069 0.0691 0.3009
Treponema pallidum prolyl-tRNA synthetase 0.0022 0.0171 1
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0038 0.0165
Brugia malayi Latrophilin receptor protein 2 0.0016 0.0094 0.034
Trypanosoma brucei glucose transporter, putative 0.0066 0.0656 0.8747
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0041 0.0385 0.2839
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0211 0.2295 0.2581
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0011 0.0046 0.0069
Trichomonas vaginalis sugar transporter, putative 0.003 0.0254 0.1106
Onchocerca volvulus 0.003 0.0258 0.1825
Trichomonas vaginalis sugar transporter, putative 0.0066 0.0656 0.286
Brugia malayi Isocitrate dehydrogenase 0.0016 0.0095 0.0341
Schistosoma mansoni protein kinase 0.0065 0.0647 0.0856
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0211 0.2295 0.2581
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0011 0.0046 0.0061
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.001 0.0032 0.0042
Trypanosoma brucei glycyl-tRNA synthetase, putative 0.0012 0.0053 0.0711
Echinococcus multilocularis thyroid hormone receptor alpha 0.001 0.0032 0.0035
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.001 0.0032 0.0035
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0182 0.2426
Loa Loa (eye worm) hypothetical protein 0.0011 0.0046 0.0138
Trichomonas vaginalis glucose transporter, putative 0.0066 0.0656 0.286
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0065 0.0647 0.0976
Loa Loa (eye worm) histone methyltransferase 0.0009 0.0018 0.0054
Trichomonas vaginalis glucose transporter, putative 0.0066 0.0656 0.286
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0065 0.0647 0.0976
Schistosoma mansoni sugar transporter 0.003 0.0254 0.0336
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0023 0.0182 0.4046
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0385 0.1676
Brugia malayi Valyl-tRNA synthetase 0.0011 0.0046 0.0128
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0182 0.0725
Chlamydia trachomatis threonine--tRNA ligase 0.0012 0.0053 0.1186
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0017 0.0116 0.2572
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0018 0.0118 0.0514
Entamoeba histolytica protein kinase, putative 0.0065 0.0647 0.6413
Onchocerca volvulus 0.003 0.0254 0.1786
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0011 0.0046 0.0455
Brugia malayi RNA, U transporter 1 0.0081 0.0827 0.3556
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0098 0.1026 0.1358
Loa Loa (eye worm) hypothetical protein 0.003 0.0254 0.0763
Brugia malayi Nuclear hormone receptor family member nhr-49 0.001 0.0032 0.0065
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0016 0.0095 0.1708
Plasmodium vivax importin-beta 2, putative 0.0028 0.0239 0.0239
Echinococcus multilocularis lamin 0.0027 0.0218 0.0245
Brugia malayi Nuclear hormone receptor family member nhr-14 0.001 0.0032 0.0065
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0385 0.1676
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0065 0.0647 0.0647
Brugia malayi Major Facilitator Superfamily protein 0.003 0.0254 0.104
Schistosoma mansoni coup transcription factor 0.001 0.0032 0.0042
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0009 0.0018 0.0024
Brugia malayi chromobox protein homolog 3 0.0038 0.0352 0.1471
Trichomonas vaginalis sugar transporter, putative 0.003 0.0254 0.1106
Plasmodium falciparum mitogen-activated protein kinase 2 0.0341 0.3758 0.3758
Schistosoma mansoni lamin 0.0027 0.0218 0.0289
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0046 0.02
Brugia malayi Cam kinase protein 1 0.0065 0.0647 0.2767
Brugia malayi cytoplasmic intermediate filament protein 0.0014 0.008 0.0276
Mycobacterium ulcerans hypothetical protein 0.0023 0.0182 0.4046
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0105 0.2023
Brugia malayi steroid hormone receptor 0.001 0.0032 0.0065
Entamoeba histolytica hypothetical protein 0.0011 0.0046 0.0455
Trichomonas vaginalis conserved hypothetical protein 0.0211 0.2295 1
Loa Loa (eye worm) hypothetical protein 0.0038 0.0352 0.1058
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0254 0.1106
Loa Loa (eye worm) hypothetical protein 0.001 0.0032 0.0095
Loa Loa (eye worm) major facilitator superfamily transporter 0.003 0.0254 0.0763
Loa Loa (eye worm) glycyl-tRNA synthetase 0.0012 0.0053 0.016
Onchocerca volvulus 0.0023 0.0182 0.121
Echinococcus granulosus expressed conserved protein 0.0091 0.0943 0.1248
Schistosoma mansoni hypothetical protein 0.0016 0.0094 0.0125
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.001 0.0032 0.0042
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0226 0.0983
Trichomonas vaginalis sugar transporter, putative 0.003 0.0254 0.1106
Entamoeba histolytica hypothetical protein 0.0011 0.0046 0.0455
Echinococcus multilocularis expressed conserved protein 0.0091 0.0943 0.1061
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0182 0.2426
Trypanosoma brucei THT1 - hexose transporter, putative 0.0066 0.0656 0.8747
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.001 0.0032 0.0095
Trypanosoma brucei glucose transporter, putative 0.0066 0.0656 0.8747
Loa Loa (eye worm) hypothetical protein 0.003 0.0254 0.0763
Loa Loa (eye worm) hypothetical protein 0.003 0.0254 0.0763
Plasmodium vivax lysine--tRNA ligase, putative 0.0047 0.045 0.045
Trypanosoma cruzi Aminoacyl-tRNA editing domain containing protein, putative 0.0011 0.0038 0.0504
Brugia malayi Major Facilitator Superfamily protein 0.003 0.0254 0.104
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.004 0.037 1
Loa Loa (eye worm) hypothetical protein 0.001 0.0032 0.0095
Schistosoma mansoni cellular tumor antigen P53 0.0049 0.0467 0.0618
Loa Loa (eye worm) hypothetical protein 0.003 0.0258 0.0777
Echinococcus multilocularis importin subunit beta 1 0.0028 0.0239 0.0269
Leishmania major importin beta-1 subunit, putative 0.0023 0.0178 0.2378
Treponema pallidum threonyl-tRNA synthetase 0.0012 0.0053 0.3113
Toxoplasma gondii protein kinase, putative 0.0597 0.663 1
Leishmania major hypothetical protein, conserved 0.003 0.0254 0.3381
Schistosoma mansoni hypothetical protein 0.0016 0.0094 0.0125
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0239 0.3182
Trichomonas vaginalis sugar transporter, putative 0.003 0.0254 0.1106
Schistosoma mansoni hypothetical protein 0.0303 0.3325 0.4402
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0063 0.0632 0.2755
Trypanosoma cruzi glucose transporter, putative 0.003 0.0254 0.3381
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0014 0.008 0.0239
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0016 0.0095 0.126
Brugia malayi Nuclear hormone receptor family member nhr-19 0.001 0.0032 0.0065
Schistosoma mansoni RAR-like nuclear receptor 0.001 0.0032 0.0042
Schistosoma mansoni nuclear hormone receptor 0.001 0.0032 0.0042
Trichomonas vaginalis sugar transporter, putative 0.003 0.0254 0.1106
Leishmania major hypothetical protein, conserved 0.0011 0.0038 0.0504
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.001 0.0032 0.0042
Onchocerca volvulus 0.003 0.0254 0.1786
Schistosoma mansoni hypothetical protein 0.0167 0.1794 0.2375
Trypanosoma cruzi hexose transporter 0.0066 0.0656 0.8747
Brugia malayi latrophilin 2 splice variant baaae 0.0034 0.0297 0.1229
Entamoeba histolytica threonyl-tRNA synthetase, putative 0.0012 0.0053 0.0529
Schistosoma mansoni thyroid hormone receptor 0.001 0.0032 0.0042
Loa Loa (eye worm) hypothetical protein 0.0023 0.0182 0.0547
Trypanosoma brucei glucose transporter, putative 0.0066 0.0656 0.8747
Trichomonas vaginalis sugar transporter, putative 0.003 0.0254 0.1106
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0046 0.02
Entamoeba histolytica protein kinase, putative 0.0065 0.0647 0.6413
Loa Loa (eye worm) hypothetical protein 0.0027 0.0218 0.0656
Echinococcus granulosus synaptic vesicle 2 protein 0.003 0.0254 0.0336
Schistosoma mansoni hypothetical protein 0.0211 0.2295 0.3038
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0013 0.0064 0.0072
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0065 0.0647 0.0728
Loa Loa (eye worm) hypothetical protein 0.003 0.0254 0.0763
Mycobacterium tuberculosis Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase)(ThrRS) (threonine-tRNA ligase) 0.0012 0.0053 0.0468
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.001 0.0032 0.0065
Schistosoma mansoni glucose transport protein 0.0211 0.2295 0.3038
Brugia malayi Heterochromatin protein 1 0.0069 0.0691 0.2958
Mycobacterium tuberculosis Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter) 0.003 0.0254 0.6499
Brugia malayi Protein cec-1. 0.0011 0.0046 0.0128
Schistosoma mansoni glucose transport protein 0.0211 0.2295 0.3038
Loa Loa (eye worm) major facilitator superfamily transporter 0.003 0.0254 0.0763
Brugia malayi glycyl-tRNA synthetase 0.0012 0.0053 0.0161
Schistosoma mansoni mixed-lineage leukemia protein mll 0.006 0.0594 0.0786
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0046 0.02
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0047 0.045 1
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.001 0.0032 0.0035
Toxoplasma gondii histone lysine methyltransferase SET1 0.0054 0.0522 0.0787
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0095 0.0106
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0065 0.0647 0.0856
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0118 0.0514
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.001 0.0032 0.0065
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0011 0.0046 0.0046
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0211 0.2295 0.3038
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0063 0.0632 0.0837
Trichomonas vaginalis sugar transporter, putative 0.003 0.0254 0.1106
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0226 0.0983
Onchocerca volvulus 0.0012 0.0053 0.0171
Echinococcus granulosus FTZ F1 alpha 0.001 0.0032 0.0042
Schistosoma mansoni Tr4/Tr2 (homologue) 0.001 0.0032 0.0042
Brugia malayi M-phase phosphoprotein, mpp8 0.0011 0.0046 0.0128
Echinococcus multilocularis solute carrier family 22 0.003 0.0254 0.0285
Brugia malayi hypothetical protein 0.003 0.0254 0.104
Chlamydia trachomatis lysine--tRNA ligase 0.0047 0.045 1
Mycobacterium tuberculosis Probable conserved integral membrane transport protein 0.003 0.0254 0.6499
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0012 0.0053 0.007
Brugia malayi nuclear receptor NHR-88 0.001 0.0032 0.0065
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0046 0.02
Loa Loa (eye worm) hypothetical protein 0.001 0.0032 0.0095
Loa Loa (eye worm) hypothetical protein 0.0016 0.0094 0.0283
Echinococcus granulosus General substrate transporter 0.0182 0.1961 0.2596
Entamoeba histolytica glycyl-tRNA synthetase, putative 0.0012 0.0053 0.0529
Trypanosoma brucei Aminoacyl-tRNA editing domain containing protein, putative 0.0011 0.0038 0.0504
Echinococcus multilocularis protein patched 0.0042 0.0387 0.0435
Trichomonas vaginalis sugar transporter, putative 0.003 0.0254 0.1106
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0017 0.0116 0.2346
Echinococcus granulosus microtubule associated protein 2 0.0679 0.7554 1
Schistosoma mansoni protein kinase 0.0065 0.0647 0.0856
Trypanosoma brucei glucose transporter, putative 0.0066 0.0656 0.8747
Entamoeba histolytica hypothetical protein 0.0011 0.0046 0.0455
Loa Loa (eye worm) hypothetical protein 0.0017 0.0116 0.0348
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.003 0.0254 1
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0023 0.0182 0.4046
Loa Loa (eye worm) hypothetical protein 0.0065 0.0647 0.1946
Trichomonas vaginalis CAMK family protein kinase 0.0065 0.0647 0.2819
Loa Loa (eye worm) hypothetical protein 0.0017 0.0116 0.0348
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0178 0.2378
Leishmania major glucose transporter, lmgt1 0.0066 0.0656 0.8747
Echinococcus granulosus nuclear receptor 2DBD gamma 0.001 0.0032 0.0042
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0023 0.0182 0.4046
Onchocerca volvulus 0.0011 0.0046 0.0115
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0065 0.0647 0.0647
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0063 0.0632 1
Trypanosoma cruzi threonyl-tRNA synthetase, putative 0.0012 0.0053 0.0711
Trichomonas vaginalis sugar transporter, putative 0.0066 0.0656 0.286
Onchocerca volvulus 0.003 0.0254 0.1786
Mycobacterium leprae Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase) (ThrRS) (Threonine-tRNA ligase) 0.0012 0.0053 0.0262
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0011 0.0046 0.02
Echinococcus multilocularis Chromobox protein 3 0.0011 0.0046 0.0052
Trichomonas vaginalis Heterochromatin protein, putative 0.0011 0.0046 0.02
Trypanosoma brucei glucose transporter, putative 0.0066 0.0656 0.8747
Loa Loa (eye worm) hypothetical protein 0.003 0.0254 0.0763
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0063 0.0632 0.2702
Echinococcus granulosus cpg binding protein 0.003 0.0256 0.0338
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0063 0.0632 0.0837
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0016 0.0095 0.0095
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0118 0.0514
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0387 0.1687
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0011 0.0046 0.0061
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0182 0.4046
Echinococcus multilocularis glycyl tRNA synthetase 0.0012 0.0053 0.006
Loa Loa (eye worm) hypothetical protein 0.0011 0.0046 0.0138
Plasmodium vivax acyl-CoA synthetase, putative 0.0017 0.0116 0.0116
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0046 0.02
Toxoplasma gondii glycyl-tRNA synthetase 0.0012 0.0053 0.008
Mycobacterium ulcerans prolyl-tRNA synthetase 0.0022 0.0171 0.3811
Echinococcus multilocularis solute carrier family 22 0.003 0.0254 0.0285
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0023 0.0182 0.4342
Echinococcus granulosus Niemann Pick C1 protein 0.0138 0.1476 0.1954
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0011 0.0046 0.0455
Plasmodium vivax threonine--tRNA ligase, putative 0.0012 0.0053 0.0053
Onchocerca volvulus 0.003 0.0254 0.1786
Trichomonas vaginalis sugar transporter, putative 0.003 0.0254 0.1106
Echinococcus granulosus lamin 0.0027 0.0218 0.0289
Brugia malayi Nuclear hormone receptor family member nhr-19 0.001 0.0032 0.0065
Loa Loa (eye worm) hypothetical protein 0.003 0.0254 0.0763
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.003 0.0254 0.0254
Schistosoma mansoni hypothetical protein 0.004 0.037 0.049
Plasmodium vivax proline--tRNA ligase, putative 0.0074 0.075 0.075
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0065 0.0647 0.0856
Schistosoma mansoni hypothetical protein 0.004 0.037 0.049
Onchocerca volvulus 0.0011 0.0046 0.0115
Brugia malayi Associated with TFs and helicases family protein 0.0011 0.0046 0.0128
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0016 0.0094 0.034
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0023 0.0182 0.4046
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0013 0.0064 0.0072
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.003 0.0254 0.3381
Plasmodium falciparum heterochromatin protein 1 0.0011 0.0046 0.0046
Schistosoma mansoni hypothetical protein 0.0167 0.1794 0.2375
Onchocerca volvulus 0.003 0.0254 0.1786
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0065 0.0647 0.0976
Echinococcus multilocularis Niemann Pick C1 protein 0.0097 0.1009 0.1135
Echinococcus granulosus Protein patched homolog 1 0.0042 0.0387 0.0513
Trypanosoma cruzi hexose transporter, putative 0.0036 0.0322 0.4296
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0063 0.0632 0.2702
Plasmodium falciparum calcium-dependent protein kinase 5 0.0065 0.0647 0.0647
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0016 0.0094 0.0125
Brugia malayi CHD4 protein 0.0013 0.0064 0.0207
Trichomonas vaginalis sugar transporter, putative 0.003 0.0254 0.1106
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0065 0.0647 0.0728
Trichomonas vaginalis sugar transporter, putative 0.003 0.0254 0.1106
Loa Loa (eye worm) hypothetical protein 0.0011 0.0046 0.0138
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.001 0.0032 0.0095
Loa Loa (eye worm) hypothetical protein 0.0012 0.0058 0.0175
Loa Loa (eye worm) hypothetical protein 0.001 0.0032 0.0095
Schistosoma mansoni hypothetical protein 0.0034 0.0297 0.0393
Schistosoma mansoni sugar transporter 0.003 0.0254 0.0336
Trichomonas vaginalis sugar transporter, putative 0.003 0.0254 0.1106
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0105 0.2023
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0178 0.0777
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0011 0.0046 0.0128
Leishmania major glucose transporter/membrane transporter D2, putative 0.0066 0.0656 0.8747
Trichomonas vaginalis sugar transporter, putative 0.003 0.0254 0.1106
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0047 0.045 0.6932
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0023 0.0182 0.4342
Trichomonas vaginalis sugar transporter, putative 0.003 0.0254 0.1106
Schistosoma mansoni retinoid-x-receptor (RXR) 0.001 0.0032 0.0042
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0065 0.0647 0.1946
Schistosoma mansoni serine/threonine protein kinase 0.0065 0.0647 0.0856
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0046 0.02
Schistosoma mansoni retinoic acid receptor RXR 0.001 0.0032 0.0042
Loa Loa (eye worm) bifunctional aminoacyl-tRNA synthetase 0.0026 0.0212 0.0638
Brugia malayi major facilitator superfamily protein 0.003 0.0254 0.104
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.0218 0.0884
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0211 0.2295 0.3038
Trichomonas vaginalis sugar transporter, putative 0.003 0.0254 0.1106
Echinococcus multilocularis snurportin 1 0.0303 0.3325 0.374
Loa Loa (eye worm) hypothetical protein 0.001 0.0032 0.0095
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0182 0.2426
Onchocerca volvulus 0.0027 0.0218 0.15
Trichomonas vaginalis conserved hypothetical protein 0.0066 0.0656 0.286
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0023 0.0182 0.2426
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0178 0.0777
Echinococcus multilocularis Chromo domain 0.0011 0.0046 0.0052
Onchocerca volvulus 0.003 0.0254 0.1786
Trichomonas vaginalis sugar transporter, putative 0.003 0.0254 0.1106
Brugia malayi major facilitator superfamily protein 0.003 0.0254 0.104
Plasmodium falciparum lysine--tRNA ligase 0.0047 0.045 0.045
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0013 0.0064 0.0085
Echinococcus granulosus glycyl tRNA synthetase 0.0012 0.0053 0.0071
Trypanosoma brucei THT1 - hexose transporter, putative 0.0066 0.0656 0.8747
Trypanosoma brucei glucose transporter 2A 0.0066 0.0656 0.8747
Trypanosoma cruzi hypothetical protein, conserved 0.0011 0.0038 0.0504
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0065 0.0647 0.0647
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.001 0.0032 0.0035
Brugia malayi Nuclear hormone receptor family member nhr-41 0.001 0.0032 0.0065
Schistosoma mansoni hypothetical protein 0.004 0.037 0.049
Loa Loa (eye worm) hypothetical protein 0.0017 0.0116 0.0348
Loa Loa (eye worm) hypothetical protein 0.003 0.0254 0.0763
Echinococcus multilocularis GPCR, family 2 0.0016 0.0094 0.0106
Toxoplasma gondii sugar transporter ST3 0.003 0.0254 0.0383
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0095 0.0106
Brugia malayi hypothetical protein 0.003 0.0254 0.104
Mycobacterium ulcerans sugar transporter 0.003 0.0254 0.5639
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0074 0.075 1
Echinococcus multilocularis geminin 0.0167 0.1794 0.2018
Echinococcus multilocularis dnaJ subfamily B 0.0402 0.4445 0.4999
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0211 0.2295 0.2581
Brugia malayi Nuclear hormone receptor family member nhr-31 0.001 0.0032 0.0065
Trichomonas vaginalis sugar transporter, putative 0.003 0.0254 0.1106
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0016 0.0094 0.0106
Echinococcus multilocularis protein dispatched 1 0.0047 0.0453 0.051
Mycobacterium ulcerans threonyl-tRNA synthetase 0.0012 0.0053 0.1186
Trypanosoma cruzi hexose transporter, putative 0.003 0.0254 0.3381
Trichomonas vaginalis sugar transporter, putative 0.003 0.0254 0.1106
Echinococcus multilocularis isocitrate dehydrogenase 0.0016 0.0095 0.0106
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0046 0.02
Echinococcus granulosus intermediate filament protein 0.0027 0.0218 0.0289
Plasmodium vivax hexose transporter 0.0211 0.2295 0.2295
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0254 0.1106
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0023 0.0182 0.2426
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0341 0.3758 0.5667
Trichomonas vaginalis chromobox protein, putative 0.0011 0.0046 0.02
Plasmodium falciparum importin beta, putative 0.0028 0.0239 0.0239
Leishmania major glucose transporter, lmgt2 0.0066 0.0656 0.8747
Trypanosoma cruzi Aminoacyl-tRNA editing domain containing protein, putative 0.0011 0.0038 0.0504
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0011 0.0046 0.0052
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0074 0.075 0.1132
Loa Loa (eye worm) hypothetical protein 0.0026 0.0213 0.0639
Entamoeba histolytica acyl-coA synthetase, putative 0.0023 0.0182 0.1804
Trichomonas vaginalis sugar transporter, putative 0.003 0.0254 0.1106
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0182 0.4046
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0063 0.0632 0.0711
Echinococcus multilocularis tumor protein p63 0.0332 0.3658 0.4114
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0178 0.0777
Echinococcus multilocularis calcium dependent protein kinase 0.0061 0.0602 0.0677
Trichomonas vaginalis chromobox protein, putative 0.0011 0.0046 0.02
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.0182 0.1804
Trichomonas vaginalis sugar transporter, putative 0.003 0.0254 0.1106
Plasmodium falciparum calcium-dependent protein kinase 2 0.0065 0.0647 0.0647
Loa Loa (eye worm) hypothetical protein 0.0011 0.0046 0.0138
Onchocerca volvulus 0.003 0.0254 0.1786
Echinococcus granulosus tumor protein p63 0.0332 0.3658 0.4842
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0074 0.075 1
Loa Loa (eye worm) hypothetical protein 0.003 0.0254 0.0763
Echinococcus granulosus Chromobox protein 3 0.0011 0.0046 0.0061
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0239 0.3182
Trichomonas vaginalis sugar transporter, putative 0.003 0.0254 0.1106
Brugia malayi Nuclear hormone receptor family member nhr-25 0.001 0.0032 0.0065
Giardia lamblia Sugar-proton symporter 0.003 0.0254 0.346
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.001 0.0032 0.0035
Schistosoma mansoni patched 1 0.0042 0.0387 0.0513
Schistosoma mansoni lysyl-tRNA synthetase 0.0047 0.045 0.0596
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.001 0.0032 0.0095
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0118 0.0514
Plasmodium falciparum acyl-CoA synthetase 0.0017 0.0116 0.0116
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0011 0.0046 0.0061
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0018 0.0118 0.0514
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.001 0.0032 0.0042
Trichomonas vaginalis sugar transporter, putative 0.003 0.0254 0.1106
Trypanosoma cruzi hexose transporter, putative 0.0066 0.0656 0.8747
Toxoplasma gondii lysine-tRNA ligase 0.0047 0.045 0.0679
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0046 0.02
Loa Loa (eye worm) sugar transporter 0.003 0.0254 0.0763
Echinococcus granulosus Chromo domain 0.0011 0.0046 0.0061
Trichomonas vaginalis sugar transporter, putative 0.0066 0.0656 0.286
Brugia malayi Steroid receptor seven-up type 2 0.001 0.0032 0.0065
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0105 0.2023
Onchocerca volvulus 0.003 0.0254 0.1786
Giardia lamblia Lysyl-tRNA synthetase 0.0047 0.045 0.6849
Loa Loa (eye worm) heterochromatin protein 1 0.0069 0.0691 0.2077
Loa Loa (eye worm) hypothetical protein 0.0011 0.0046 0.0138
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0041 0.0385 0.1676
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.0218 0.0656
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.001 0.0032 0.0095
Loa Loa (eye worm) hypothetical protein 0.0063 0.0632 0.1902
Brugia malayi CHE-14 protein 0.0042 0.0387 0.1626
Brugia malayi Nuclear hormone receptor family member nhr-1 0.001 0.0032 0.0065
Loa Loa (eye worm) hypothetical protein 0.0121 0.1275 0.3835
Echinococcus granulosus lysyl tRNA synthetase 0.0047 0.045 0.0596
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0063 0.0632 0.6267
Brugia malayi isocitrate dehydrogenase 0.0016 0.0095 0.0341
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0182 0.0725
Onchocerca volvulus Putative transporter 0.003 0.0254 0.1786
Loa Loa (eye worm) hypothetical protein 0.003 0.0254 0.0763
Trichomonas vaginalis sugar transporter, putative 0.003 0.0254 0.1106
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.001 0.0032 0.0095
Brugia malayi Importin beta-1 subunit 0.0028 0.0239 0.0974
Echinococcus granulosus solute carrier family 22 0.003 0.0254 0.0336
Onchocerca volvulus 0.003 0.0254 0.1786
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0105 0.2023
Loa Loa (eye worm) hypothetical protein 0.003 0.0254 0.0763
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0016 0.0095 0.0095
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0065 0.0647 0.0856
Schistosoma mansoni chromobox protein 0.0011 0.0046 0.0061
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0047 0.045 1
Plasmodium vivax CDK-related protein kinase 6, putative 0.0897 1 1
Loa Loa (eye worm) CHromoDomain protein family member 0.0013 0.0064 0.0193
Loa Loa (eye worm) hypothetical protein 0.0023 0.0182 0.0547
Chlamydia trachomatis proline--tRNA ligase 0.0022 0.0171 0.3811
Onchocerca volvulus 0.003 0.0254 0.1786
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0341 0.3758 0.3758
Trichomonas vaginalis sugar transporter, putative 0.003 0.0254 0.1106
Schistosoma mansoni hypothetical protein 0.004 0.037 0.049
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0011 0.0046 0.0069
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0211 0.2295 0.3038
Onchocerca volvulus 0.003 0.0254 0.1786
Toxoplasma gondii HEAT repeat-containing protein 0.0028 0.0239 0.036
Trypanosoma brucei glucose transporter, putative 0.0066 0.0656 0.8747
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.001 0.0032 0.0042
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0038 0.0165
Wolbachia endosymbiont of Brugia malayi prolyl-tRNA synthetase 0.0012 0.0053 0.2103
Echinococcus granulosus solute carrier family 22 0.003 0.0254 0.0336
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.001 0.0032 0.0035
Echinococcus granulosus snurportin 1 0.0303 0.3325 0.4402
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.003 0.0254 0.5639
Echinococcus multilocularis lysyl tRNA synthetase 0.0047 0.045 0.0506
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0016 0.0094 0.0106
Schistosoma mansoni cpg binding protein 0.003 0.0256 0.0338
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0049 0.0471 0.1995
Brugia malayi CXXC zinc finger family protein 0.0028 0.0237 0.0969
Trichomonas vaginalis sugar transporter, putative 0.003 0.0254 0.1106
Trypanosoma cruzi sugar transporter, putative 0.003 0.0254 0.3381
Brugia malayi Nuclear hormone receptor family member nhr-40 0.001 0.0032 0.0065
Loa Loa (eye worm) hypothetical protein 0.0063 0.0632 0.1902
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0016 0.0095 0.126
Schistosoma mansoni hypothetical protein 0.0016 0.0094 0.0125
Brugia malayi Nuclear hormone receptor-like 1 0.001 0.0032 0.0065
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.001 0.0032 0.0095
Echinococcus granulosus importin subunit beta 1 0.0028 0.0239 0.0316
Trichomonas vaginalis chromobox protein, putative 0.0011 0.0046 0.02
Brugia malayi hypothetical protein 0.003 0.0254 0.104
Brugia malayi photoreceptor-specific nuclear receptor 0.001 0.0032 0.0065
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0013 0.0064 0.0084
Onchocerca volvulus 0.003 0.0254 0.1786
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0095 0.126
Trichomonas vaginalis sugar transport protein, putative 0.003 0.0254 0.1106
Echinococcus granulosus chromobox protein 1 0.0069 0.0691 0.0914
Trichomonas vaginalis sugar transporter, putative 0.003 0.0254 0.1106
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0011 0.0046 0.02
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.001 0.0032 0.0035
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0065 0.0647 0.0728
Trypanosoma cruzi threonyl-tRNA synthetase, putative 0.0012 0.0053 0.0711
Entamoeba histolytica hypothetical protein 0.0047 0.045 0.4459
Trichomonas vaginalis chromobox protein, putative 0.0069 0.0691 0.3009
Echinococcus multilocularis lamin dm0 0.0027 0.0218 0.0245
Schistosoma mansoni microtubule-associated protein tau 0.0679 0.7554 1
Brugia malayi hypothetical protein 0.0121 0.1275 0.5524
Loa Loa (eye worm) hypothetical protein 0.0034 0.0297 0.0892
Brugia malayi hypothetical protein 0.0011 0.0046 0.0128
Schistosoma mansoni lamin 0.0027 0.0218 0.0289
Loa Loa (eye worm) hypothetical protein 0.0047 0.045 0.1353
Loa Loa (eye worm) hypothetical protein 0.0017 0.0116 0.0348
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0049 0.0471 0.1417
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0011 0.0046 0.0455
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.001 0.0032 0.0042
Schistosoma mansoni importin beta-1 0.0028 0.0239 0.0316
Plasmodium falciparum hexose transporter 0.0211 0.2295 0.2295
Trichomonas vaginalis myo-inositol transporter, putative 0.003 0.0254 0.1106
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0065 0.0647 0.0728
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0118 0.0514
Plasmodium falciparum threonine--tRNA ligase 0.0012 0.0053 0.0053
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0074 0.075 1
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0011 0.0046 0.0069
Echinococcus multilocularis General substrate transporter 0.0182 0.1961 0.2205
Trypanosoma cruzi hexose transporter, putative 0.0066 0.0656 0.8747
Echinococcus multilocularis microtubule associated protein 2 0.0679 0.7554 0.8497
Schistosoma mansoni sugar transporter 0.003 0.0254 0.0336
Echinococcus granulosus sterol regulatory element binding protein 0.0042 0.0387 0.0513
Plasmodium vivax hypothetical protein, conserved 0.0011 0.0046 0.0046
Loa Loa (eye worm) hypothetical protein 0.0049 0.0471 0.1417
Schistosoma mansoni hypothetical protein 0.0402 0.4445 0.5884
Leishmania major protein kinase, putative 0.0065 0.0647 0.8623
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0352 0.1533
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0182 0.4046
Echinococcus multilocularis synaptic vesicle 2 protein 0.003 0.0254 0.0285
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0011 0.0046 0.02
Loa Loa (eye worm) intermediate filament protein 0.0027 0.0218 0.0656
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0352 0.1533
Echinococcus granulosus lamin dm0 0.0027 0.0218 0.0289
Loa Loa (eye worm) threonyl-tRNA synthetase 0.0012 0.0053 0.016
Onchocerca volvulus 0.0027 0.0218 0.15
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.0182 0.1804
Trichomonas vaginalis sugar transporter, putative 0.003 0.0254 0.1106
Echinococcus multilocularis chromobox protein 2 0.0011 0.0046 0.0052
Loa Loa (eye worm) hypothetical protein 0.0011 0.0046 0.0138
Trypanosoma cruzi hypothetical protein, conserved 0.0011 0.0038 0.0504
Schistosoma mansoni chromobox protein 0.0011 0.0046 0.0061
Loa Loa (eye worm) hypothetical protein 0.0023 0.0182 0.0547
Echinococcus granulosus chromobox protein 1 0.0069 0.0691 0.0914
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0016 0.0095 0.0125
Toxoplasma gondii transporter, major facilitator family protein 0.003 0.0254 0.0383
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0095 0.0106
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0009 0.0018 0.002
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0011 0.0046 0.0046
Mycobacterium ulcerans glycyl-tRNA synthetase 0.0012 0.0053 0.1186
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0014 0.0079 0.0345
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0063 0.0632 0.0837
Trypanosoma brucei THT1 - hexose transporter, putative 0.0066 0.0656 0.8747
Mycobacterium ulcerans integral membrane transport protein 0.003 0.0254 0.5639
Toxoplasma gondii sugar transporter ST2 0.003 0.0254 0.0383
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.001 0.0032 0.0042
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0095 0.126

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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