Detailed information for compound 665260

Basic information

Technical information
  • TDR Targets ID: 665260
  • Name: N-(2-adamantyl)-2-(4-propan-2-ylphenoxy)aceta mide
  • MW: 327.46 | Formula: C21H29NO2
  • H donors: 1 H acceptors: 1 LogP: 4.75 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC(c1ccc(cc1)OCC(=O)NC1C2CC3CC1CC(C2)C3)C
  • InChi: 1S/C21H29NO2/c1-13(2)16-3-5-19(6-4-16)24-12-20(23)22-21-17-8-14-7-15(10-17)11-18(21)9-14/h3-6,13-15,17-18,21H,7-12H2,1-2H3,(H,22,23)
  • InChiKey: HDIOWSVRPZESSP-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-(2-adamantyl)-2-(4-isopropylphenoxy)acetamide
  • N-(2-adamantyl)-2-(4-propan-2-ylphenoxy)ethanamide
  • Oprea1_058841
  • STK015011
  • ZINC00303478

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Toxoplasma gondii aldehyde dehydrogenase 0.006 0.0348 0.1267
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0042 0.0148 0.0192
Echinococcus granulosus voltage dependent calcium channel 0.0709 0.7707 0.7703
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.037 0.3871 1
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0792 0.8648 0.8645
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.006 0.0348 0.0329
Loa Loa (eye worm) norepinephrine transporter 0.0499 0.5329 0.5329
Brugia malayi PAS domain containing protein 0.0048 0.0213 0.0277
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.2923 1
Schistosoma mansoni jumonji domain containing protein 0.0059 0.0346 0.0327
Schistosoma mansoni alpha-glucosidase 0.0301 0.3086 0.3072
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.037 0.3871 1
Echinococcus multilocularis sodium channel protein 0.0211 0.2067 0.2052
Loa Loa (eye worm) hypothetical protein 0.0159 0.1476 0.1476
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0135 0.1205 0.1205
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0085 0.0632 0.0821
Brugia malayi hypoxia-induced factor 1 0.0148 0.1347 0.1748
Trypanosoma cruzi hypothetical protein, conserved 0.0078 0.0552 0.1427
Brugia malayi hypothetical protein 0.0148 0.1345 0.1745
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0085 0.0632 0.0614
Echinococcus multilocularis lysine specific demethylase 5A 0.0059 0.0346 0.0327
Schistosoma mansoni jumonji/arid domain-containing protein 0.0059 0.0346 0.0327
Schistosoma mansoni hypothetical protein 0.0034 0.0062 0.0042
Loa Loa (eye worm) hypothetical protein 0.0709 0.7707 0.7707
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0085 0.0632 0.0614
Echinococcus granulosus lysosomal alpha glucosidase 0.035 0.3638 0.3626
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0287 0.2923 1
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0034 0.0062 0.0042
Brugia malayi jmjC domain containing protein 0.0059 0.0346 0.0449
Loa Loa (eye worm) hypothetical protein 0.0181 0.1723 0.1723
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.006 0.0348 0.0329
Echinococcus multilocularis survival motor neuron protein 1 0.0265 0.268 0.2665
Onchocerca volvulus 0.0499 0.5329 1
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.014 0.126 1
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0135 0.1205 0.1187
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0109 0.0903 0.0903
Trichomonas vaginalis alpha-glucosidase, putative 0.0078 0.0552 0.1889
Loa Loa (eye worm) jmjC domain-containing protein 0.0059 0.0346 0.0346
Loa Loa (eye worm) hypothetical protein 0.0499 0.5329 0.5329
Brugia malayi hypothetical protein 0.0085 0.0632 0.0821
Brugia malayi Calcitonin receptor-like protein seb-1 0.0109 0.0903 0.1172
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0085 0.0632 0.0614
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0085 0.0632 0.0821
Brugia malayi jmjC domain containing protein 0.0059 0.0346 0.0449
Schistosoma mansoni sodium/chloride dependent transporter 0.0085 0.0632 0.0614
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0094 0.0736 0.2519
Echinococcus granulosus single minded 2 0.0035 0.0073 0.0053
Toxoplasma gondii hypothetical protein 0.0085 0.0632 0.3075
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0348 0.2315
Echinococcus granulosus survival motor neuron protein 1 0.0265 0.268 0.2665
Leishmania major importin beta-1 subunit, putative 0.0069 0.0457 0.827
Schistosoma mansoni hypothetical protein 0.0911 1 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.2923 1
Plasmodium vivax amine transporter, putative 0.0085 0.0632 0.9853
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.035 0.3638 0.3638
Giardia lamblia Fructose-bisphosphate aldolase 0.0287 0.2923 1
Trichomonas vaginalis maltase-glucoamylase, putative 0.0078 0.0552 0.1889
Schistosoma mansoni hypothetical protein 0.0034 0.0062 0.0042
Toxoplasma gondii HEAT repeat-containing protein 0.0085 0.064 0.3121
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0085 0.0632 0.3075
Loa Loa (eye worm) hypothetical protein 0.0085 0.064 0.064
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.014 0.126 1
Echinococcus multilocularis lysosomal alpha glucosidase 0.035 0.3638 0.3626
Loa Loa (eye worm) hypothetical protein 0.0031 0.002 0.002
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.2923 1
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0042 0.0148 0.0148
Brugia malayi Latrophilin receptor protein 2 0.0034 0.0062 0.008
Echinococcus multilocularis snurportin 1 0.0911 1 1
Brugia malayi latrophilin 2 splice variant baaae 0.0074 0.0514 0.0667
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0059 0.0346 0.0327
Loa Loa (eye worm) hypothetical protein 0.0054 0.028 0.028
Toxoplasma gondii transporter, cation channel family protein 0.0181 0.1723 1
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0499 0.5329 0.5319
Loa Loa (eye worm) hypothetical protein 0.0085 0.0632 0.0632
Schistosoma mansoni sodium/chloride dependent transporter 0.0085 0.0632 0.0614
Plasmodium vivax hypothetical protein, conserved 0.0085 0.0632 0.9853
Schistosoma mansoni aldehyde dehydrogenase 0.006 0.0348 0.0329
Schistosoma mansoni alpha glucosidase 0.0078 0.0552 0.0534
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0287 0.2923 1
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0085 0.0632 0.0614
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0078 0.0552 0.1889
Schistosoma mansoni hypothetical protein 0.0054 0.0286 0.0266
Onchocerca volvulus 0.0202 0.1966 0.369
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0069 0.0457 0.1562
Loa Loa (eye worm) hypothetical protein 0.0148 0.1345 0.1345
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0211 0.2067 0.2052
Onchocerca volvulus 0.0035 0.0073 0.0136
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0094 0.0736 0.2519
Loa Loa (eye worm) hypothetical protein 0.0034 0.0062 0.0062
Trichomonas vaginalis ran, putative 0.0042 0.0148 0.0507
Loa Loa (eye worm) follicle stimulating hormone receptor 0.028 0.2851 0.2851
Brugia malayi bHLH-PAS transcription factor 0.0035 0.0073 0.0094
Trichomonas vaginalis sucrase-isomaltase, putative 0.0078 0.0552 0.1889
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0085 0.0632 0.5
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0709 0.7707 0.7703
Leishmania major GTP-binding protein, putative 0.0042 0.0148 0.2683
Schistosoma mansoni cellular tumor antigen P53 0.0054 0.028 0.026
Schistosoma mansoni aryl hydrocarbon receptor 0.0048 0.0213 0.0194
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0709 0.7707 0.7703
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0085 0.0632 0.0614
Loa Loa (eye worm) hypothetical protein 0.0094 0.0736 0.0736
Loa Loa (eye worm) hypothetical protein 0.0085 0.0632 0.0632
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0085 0.0632 0.0614
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0085 0.0632 0.0632
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0709 0.7707 0.7703
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0085 0.0632 0.0821
Echinococcus multilocularis voltage dependent calcium channel 0.0709 0.7707 0.7703
Brugia malayi Intermediate filament tail domain containing protein 0.0031 0.002 0.0026
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0034 0.0062 0.0042
Loa Loa (eye worm) hypothetical protein 0.0265 0.268 0.268
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0069 0.0457 0.1562
Entamoeba histolytica Ran family GTPase 0.0042 0.0148 0.0507
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0059 0.0346 0.0327
Loa Loa (eye worm) hypothetical protein 0.0085 0.0632 0.0632
Trichomonas vaginalis alpha-glucosidase, putative 0.0078 0.0552 0.1889
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.2923 1
Schistosoma mansoni ran 0.0042 0.0148 0.0129
Echinococcus multilocularis transfer RNA-Lys 0.0035 0.0073 0.0053
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0042 0.0148 0.0383
Toxoplasma gondii hypothetical protein 0.0085 0.0632 0.3075
Brugia malayi hypothetical protein 0.0265 0.268 0.3477
Schistosoma mansoni ran 0.0042 0.0148 0.0129
Brugia malayi intermediate filament protein 0.0031 0.002 0.0026
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.006 0.0348 0.6295
Trypanosoma brucei importin beta-1 subunit, putative 0.0085 0.064 0.1653
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0031 0.002 0.002
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0135 0.1205 0.1187
Loa Loa (eye worm) serotonin transporter b 0.0499 0.5329 0.5329
Loa Loa (eye worm) latrophilin receptor protein 2 0.0034 0.0062 0.0062
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0085 0.0632 0.0614
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0054 0.0286 0.0371
Trypanosoma cruzi hypothetical protein, conserved 0.0078 0.0552 0.1427
Trichomonas vaginalis importin beta-1, putative 0.0069 0.0457 0.1562
Schistosoma mansoni sodium/chloride dependent transporter 0.0499 0.5329 0.5319
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0042 0.0148 0.0383
Loa Loa (eye worm) hypothetical protein 0.0074 0.0514 0.0514
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0135 0.1205 0.1187
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0034 0.0062 0.0042
Onchocerca volvulus 0.0085 0.0632 0.1187
Loa Loa (eye worm) hypothetical protein 0.0085 0.0632 0.0632
Schistosoma mansoni voltage-gated cation channel 0.0709 0.7707 0.7703
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0085 0.0632 0.0614
Echinococcus granulosus tumor protein p63 0.0366 0.3822 0.381
Loa Loa (eye worm) solute carrier family 6 member 4 0.0499 0.5329 0.5329
Onchocerca volvulus 0.0054 0.0286 0.0536
Brugia malayi Glycosyl hydrolases family 31 protein 0.035 0.3638 0.4721
Plasmodium falciparum importin beta, putative 0.0085 0.064 1
Loa Loa (eye worm) voltage-dependent calcium channel 0.0181 0.1723 0.1723
Echinococcus granulosus sodium and chloride dependent glycine 0.0085 0.0632 0.0614
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0085 0.0632 0.0614
Onchocerca volvulus 0.0054 0.028 0.0525
Echinococcus multilocularis tumor protein p63 0.0366 0.3822 0.381
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0709 0.7707 1
Leishmania major alpha glucosidase II subunit, putative 0.0078 0.0552 1
Echinococcus multilocularis lysosomal alpha glucosidase 0.035 0.3638 0.3626
Echinococcus multilocularis importin subunit beta 1 0.0085 0.064 0.0621
Onchocerca volvulus 0.0031 0.002 0.0037
Echinococcus multilocularis neutral alpha glucosidase AB 0.0078 0.0552 0.0534
Echinococcus granulosus serotonin transporter 0.0499 0.5329 0.5319
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0078 0.0552 0.1889
Onchocerca volvulus 0.0085 0.0632 0.1187
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0709 0.7707 0.7703
Onchocerca volvulus 0.0085 0.0632 0.1187
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0078 0.0552 0.2566
Loa Loa (eye worm) hypothetical protein 0.0499 0.5329 0.5329
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0135 0.1205 0.1187
Schistosoma mansoni jumonji/arid domain-containing protein 0.0059 0.0346 0.0327
Entamoeba histolytica hypothetical protein 0.0069 0.0457 0.1562
Echinococcus granulosus lysine specific demethylase 5A 0.0059 0.0346 0.0327
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0085 0.0632 0.0614
Loa Loa (eye worm) hypothetical protein 0.0085 0.0632 0.0632
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0078 0.0552 0.1889
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0034 0.0062 0.008
Echinococcus multilocularis voltage dependent calcium channel 0.0709 0.7707 0.7703
Brugia malayi RNA, U transporter 1 0.0243 0.2423 0.3144
Brugia malayi Importin beta-1 subunit 0.0085 0.064 0.083
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0709 0.7707 0.7703
Loa Loa (eye worm) hypothetical protein 0.0159 0.1476 0.1476
Schistosoma mansoni hypothetical protein 0.0034 0.0062 0.0042
Loa Loa (eye worm) hypothetical protein 0.0109 0.0903 0.0903
Schistosoma mansoni hypothetical protein 0.0074 0.0514 0.0495
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0085 0.0632 0.0614
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0034 0.0062 0.0042
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0085 0.0632 0.0614
Echinococcus granulosus neutral alpha glucosidase AB 0.0078 0.0552 0.0534
Plasmodium falciparum transporter, putative 0.0085 0.0632 0.9853
Schistosoma mansoni sodium-dependent amino acid transporter 0.0085 0.0632 0.0614
Schistosoma mansoni single-minded 0.0048 0.0213 0.0194
Echinococcus granulosus GPCR family 2 0.0034 0.0062 0.0042
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0135 0.1205 0.1187
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0085 0.0632 0.0614
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0085 0.0632 0.3075
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0042 0.0148 0.0383
Loa Loa (eye worm) intermediate filament protein 0.0031 0.002 0.002
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0085 0.0632 0.3075
Onchocerca volvulus 0.0031 0.002 0.0037
Echinococcus multilocularis sodium and chloride dependent glycine 0.0085 0.0632 0.0614
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0135 0.1205 0.1563
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.2923 1
Echinococcus granulosus sodium and chloride dependent glycine 0.0085 0.0632 0.0614
Echinococcus granulosus voltage dependent calcium channel 0.0181 0.1723 0.1707
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0085 0.0632 0.0614
Toxoplasma gondii hypothetical protein 0.0159 0.1476 0.8429
Brugia malayi hypothetical protein 0.016 0.1488 0.193
Schistosoma mansoni importin beta-1 0.0085 0.064 0.0621
Loa Loa (eye worm) hypothetical protein 0.003 0.0013 0.0013
Brugia malayi Glycosyl hydrolases family 31 protein 0.0078 0.0552 0.0717
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0499 0.5329 0.6914
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0078 0.0552 0.0552
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0078 0.0552 0.1889
Echinococcus multilocularis serotonin transporter 0.0499 0.5329 0.5319
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.2923 1
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0135 0.1205 0.1187
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0085 0.0632 0.0614
Onchocerca volvulus 0.0148 0.1345 0.2524
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.014 0.126 0.5
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0911 1 1
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0709 0.7707 0.7703
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0042 0.0148 0.0129
Schistosoma mansoni aldehyde dehydrogenase 0.006 0.0348 0.0329
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0135 0.1205 0.1187
Trichomonas vaginalis alpha-glucosidase, putative 0.0078 0.0552 0.1889
Trichomonas vaginalis alpha-glucosidase, putative 0.0078 0.0552 0.1889
Trichomonas vaginalis alpha-glucosidase, putative 0.0078 0.0552 0.1889
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0348 0.2315
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.2923 1
Brugia malayi follicle stimulating hormone receptor 0.028 0.2851 0.37
Loa Loa (eye worm) hypothetical protein 0.0085 0.0632 0.0632
Echinococcus multilocularis sodium and chloride dependent glycine 0.0085 0.0632 0.0614
Plasmodium vivax importin-beta 2, putative 0.0085 0.064 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.2923 1
Schistosoma mansoni survival motor neuron protein 0.0054 0.0286 0.0266
Trypanosoma brucei importin beta-1 subunit, putative 0.0085 0.064 0.1653
Echinococcus multilocularis GPCR, family 2 0.0034 0.0062 0.0042
Loa Loa (eye worm) calcium channel 0.0709 0.7707 0.7707
Loa Loa (eye worm) hypothetical protein 0.016 0.1488 0.1488
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0709 0.7707 0.7703
Trypanosoma cruzi importin beta-1 subunit, putative 0.0069 0.0457 0.118
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0109 0.0903 0.1172
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0709 0.7707 0.7703
Schistosoma mansoni hypothetical protein 0.0034 0.0062 0.0042
Loa Loa (eye worm) hypoxia-induced factor 1 0.0148 0.1347 0.1347
Echinococcus granulosus GTP binding nuclear protein Ran 0.0042 0.0148 0.0129
Echinococcus granulosus importin subunit beta 1 0.0085 0.064 0.0621
Treponema pallidum sodium- and chloride- dependent transporter 0.0499 0.5329 1
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0085 0.0632 0.0821
Loa Loa (eye worm) hypothetical protein 0.0085 0.0632 0.0632
Schistosoma mansoni alpha-glucosidase 0.0301 0.3086 0.3072
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0709 0.7707 0.7703
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0348 0.2315
Plasmodium falciparum amino acid transporter, putative 0.0085 0.0632 0.9853
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0085 0.0632 0.0632
Loa Loa (eye worm) hypothetical protein 0.0499 0.5329 0.5329
Trypanosoma brucei glucosidase, putative 0.0078 0.0552 0.1427

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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