Detailed information for compound 693437

Basic information

Technical information
  • TDR Targets ID: 693437
  • Name: N-[2-(2,3-dihydroindol-1-yl)-2-furan-2-ylethy l]-4-fluorobenzamide
  • MW: 350.386 | Formula: C21H19FN2O2
  • H donors: 1 H acceptors: 1 LogP: 3.78 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: Fc1ccc(cc1)C(=O)NCC(N1CCc2c1cccc2)c1ccco1
  • InChi: 1S/C21H19FN2O2/c22-17-9-7-16(8-10-17)21(25)23-14-19(20-6-3-13-26-20)24-12-11-15-4-1-2-5-18(15)24/h1-10,13,19H,11-12,14H2,(H,23,25)
  • InChiKey: VYYPIXNIUJFWFJ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • 4-fluoro-N-[2-(2-furyl)-2-indolin-1-yl-ethyl]benzamide
  • 4-fluoro-N-[2-(2-furyl)-2-(1-indolinyl)ethyl]benzamide
  • N-[2-(2,3-dihydroindol-1-yl)-2-furan-2-yl-ethyl]-4-fluoro-benzamide

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.002 0.0287 0.0743
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0643 0.1667
Echinococcus multilocularis regulator of G protein signaling 3 0.002 0.0287 0.0405
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0011 0.0112 0.0112
Echinococcus multilocularis GPCR, family 2 0.0016 0.0209 0.0295
Leishmania major mitochondrial DNA polymerase beta 0.0327 0.6779 1
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.002 0.0297 0.0297
Loa Loa (eye worm) steroid hormone receptor 0.0011 0.0112 0.0112
Schistosoma mansoni serine/threonine protein kinase 0.0189 0.3859 1
Schistosoma mansoni coup transcription factor 0.0011 0.0112 0.029
Echinococcus granulosus regulator of G protein signaling 7 0.002 0.0287 0.0405
Loa Loa (eye worm) hypothetical protein 0.0036 0.0643 0.0643
Brugia malayi Steroid receptor seven-up type 2 0.0011 0.0112 0.0112
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0046 0.0845 0.033
Echinococcus granulosus regulator of G protein signaling 3 0.002 0.0287 0.0405
Echinococcus granulosus ecdysone induced protein 78C 0.0011 0.0112 0.0158
Loa Loa (eye worm) hypothetical protein 0.0011 0.0112 0.0112
Loa Loa (eye worm) hypothetical protein 0.0016 0.0209 0.0209
Echinococcus multilocularis survival motor neuron protein 1 0.0239 0.4923 0.6945
Loa Loa (eye worm) hypothetical protein 0.0011 0.0112 0.0112
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0287 0.0553
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0327 0.6779 1
Echinococcus granulosus histone lysine methyltransferase setb 0.0031 0.0521 0.0735
Brugia malayi A-kinase anchor protein 10, precursor 0.002 0.0287 0.0287
Schistosoma mansoni nuclear hormone receptor 0.0011 0.0112 0.029
Plasmodium vivax hypothetical protein, conserved 0.0036 0.0643 1
Toxoplasma gondii ABC1 family protein 0.0036 0.0643 0.2166
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.002 0.0287 0.0405
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.005 0.0931 0.0931
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0643 0.1281
Echinococcus multilocularis expressed protein 0.002 0.0287 0.0405
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0011 0.0112 0.0112
Echinococcus granulosus mixed lineage leukemia protein mll 0.0008 0.0054 0.0076
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0011 0.0112 0.029
Loa Loa (eye worm) hypothetical protein 0.0011 0.0112 0.0112
Brugia malayi Pre-SET motif family protein 0.021 0.4299 0.4299
Brugia malayi nuclear receptor NHR-88 0.0011 0.0112 0.0112
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0046 0.0845 0.033
Mycobacterium leprae conserved hypothetical protein 0.0036 0.0643 0.5
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0031 0.0521 0.135
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0327 0.6779 1
Schistosoma mansoni regulator of G protein signaling 0.002 0.0287 0.0743
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0155 0.3142 0.4073
Echinococcus granulosus cpg binding protein 0.0031 0.0537 0.0758
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0011 0.0112 0.0158
Schistosoma mansoni hypothetical protein 0.0034 0.0597 0.1546
Onchocerca volvulus 0.0239 0.4908 0.485
Brugia malayi Regulator of G protein signaling domain containing protein 0.002 0.0287 0.0287
Schistosoma mansoni serine/threonine protein kinase 0.0189 0.3859 1
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0011 0.0112 0.0112
Loa Loa (eye worm) hypothetical protein 0.0036 0.0643 0.0643
Loa Loa (eye worm) hypothetical protein 0.005 0.0931 0.0931
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0008 0.0054 0.0076
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0016 0.0209 0.0295
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0287 0.0553
Onchocerca volvulus 0.003 0.0501 0.0394
Brugia malayi steroid hormone receptor 0.0011 0.0112 0.0112
Echinococcus multilocularis beta LACTamase domain containing family member 0.0036 0.0643 0.0907
Brugia malayi Latrophilin receptor protein 2 0.0016 0.0209 0.0209
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.0484 0.0683
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0011 0.0112 0.0112
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0643 0.1281
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0011 0.0112 0.029
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0011 0.0112 0.0158
Echinococcus multilocularis regulator of G protein signaling 0.002 0.0287 0.0405
Trichomonas vaginalis esterase, putative 0.0036 0.0643 0.1281
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0233 0.4785 1
Schistosoma mansoni z-protein (S1r protein) 0.002 0.0287 0.0743
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0011 0.0112 0.0158
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.002 0.0287 0.0553
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.001 0.0092 0.013
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0297 0.0769
Echinococcus granulosus beta LACTamase domain containing family member 0.0036 0.0643 0.0907
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.002 0.0287 0.0743
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0031 0.0521 0.0735
Loa Loa (eye worm) hypothetical protein 0.0011 0.0112 0.0112
Onchocerca volvulus 0.005 0.093 0.0828
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0643 0.1281
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0521 0.135
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0011 0.0112 0.0158
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.014 0.2832 0.3996
Schistosoma mansoni hypothetical protein 0.014 0.2832 0.7338
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0327 0.6779 1
Loa Loa (eye worm) hypothetical protein 0.048 1 1
Brugia malayi beta-lactamase 0.0036 0.0643 0.0643
Brugia malayi beta-lactamase family protein 0.0036 0.0643 0.0643
Loa Loa (eye worm) hypothetical protein 0.0011 0.0112 0.0112
Onchocerca volvulus 0.048 1 1
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0011 0.0112 0.0112
Loa Loa (eye worm) latrophilin receptor protein 2 0.0016 0.0209 0.0209
Schistosoma mansoni hypothetical protein 0.0016 0.0209 0.0541
Loa Loa (eye worm) PXA domain-containing protein 0.002 0.0287 0.0287
Echinococcus granulosus Regulator of G protein signaling 20 0.002 0.0287 0.0405
Echinococcus granulosus regulator of G protein signaling 7 0.002 0.0287 0.0405
Echinococcus granulosus axis inhibition protein axin 0.002 0.0287 0.0405
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0011 0.0112 0.0112
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0008 0.0054 0.0076
Loa Loa (eye worm) hypothetical protein 0.002 0.0287 0.0287
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0011 0.0112 0.0158
Schistosoma mansoni regulator of G protein signaling 0.002 0.0287 0.0743
Brugia malayi regulator of G-protein signaling rgs-7 0.002 0.0287 0.0287
Echinococcus multilocularis beta adrenergic receptor kinase 0.0189 0.3859 0.5445
Loa Loa (eye worm) hypothetical protein 0.002 0.0287 0.0287
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0155 0.3142 0.4073
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0011 0.0112 0.0112
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0046 0.0845 0.033
Brugia malayi beta-lactamase family protein 0.0036 0.0643 0.0643
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0011 0.0112 0.029
Schistosoma mansoni retinoic acid receptor RXR 0.0011 0.0112 0.029
Onchocerca volvulus 0.0036 0.0643 0.0537
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0031 0.0521 0.0735
Loa Loa (eye worm) hypothetical protein 0.0011 0.0112 0.0112
Schistosoma mansoni steroid hormone receptor ad4bp 0.0011 0.0112 0.029
Echinococcus multilocularis regulator of G protein signaling 3 0.002 0.0287 0.0405
Loa Loa (eye worm) hypothetical protein 0.002 0.0287 0.0287
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0016 0.0209 0.0295
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0155 0.3142 0.4073
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0011 0.0112 0.0158
Loa Loa (eye worm) hypothetical protein 0.0011 0.0112 0.0112
Loa Loa (eye worm) hypothetical protein 0.0036 0.0643 0.0643
Echinococcus multilocularis Protein lozenge 0.006 0.1145 0.1615
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0011 0.0112 0.0158
Schistosoma mansoni hypothetical protein 0.0049 0.0904 0.2343
Loa Loa (eye worm) runx1 0.006 0.1145 0.1145
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0011 0.0112 0.0112
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0521 0.135
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0521 0.135
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0036 0.0643 0.0643
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0011 0.0112 0.0112
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0643 0.1281
Schistosoma mansoni cellular tumor antigen P53 0.005 0.093 0.2411
Loa Loa (eye worm) beta-lactamase 0.0036 0.0643 0.0643
Onchocerca volvulus 0.0031 0.0521 0.0413
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.002 0.0297 0.0297
Brugia malayi hypothetical protein 0.002 0.0287 0.0287
Schistosoma mansoni cpg binding protein 0.0031 0.0537 0.1392
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0011 0.0112 0.029
Loa Loa (eye worm) hypothetical protein 0.0011 0.0112 0.0112
Toxoplasma gondii histone lysine methyltransferase SET1 0.0057 0.1086 1
Entamoeba histolytica hypothetical protein 0.002 0.0287 0.5
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0011 0.0112 0.0112
Echinococcus multilocularis axis inhibition protein axin 0.002 0.0287 0.0405
Loa Loa (eye worm) hypothetical protein 0.002 0.0287 0.0287
Schistosoma mansoni hypothetical protein 0.0016 0.0209 0.0541
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0011 0.0112 0.029
Trichomonas vaginalis set domain proteins, putative 0.0239 0.4908 1
Schistosoma mansoni thyroid hormone receptor 0.0151 0.307 0.7954
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0049 0.0904 0.0904
Loa Loa (eye worm) CXXC zinc finger family protein 0.003 0.0501 0.0501
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0643 0.1667
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.014 0.2832 0.3996
Loa Loa (eye worm) histone methyltransferase 0.001 0.0092 0.0092
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.002 0.0287 0.0743
Schistosoma mansoni cpg binding protein 0.0031 0.0537 0.1392
Echinococcus granulosus tumor protein p63 0.0342 0.7088 1
Loa Loa (eye worm) pigment dispersing factor receptor c 0.005 0.0931 0.0931
Brugia malayi F/Y-rich N-terminus family protein 0.001 0.0089 0.0089
Echinococcus multilocularis ecdysone induced protein 78C 0.0011 0.0112 0.0158
Brugia malayi CXXC zinc finger family protein 0.003 0.0501 0.0501
Loa Loa (eye worm) hypothetical protein 0.0036 0.0643 0.0643
Loa Loa (eye worm) RGS-3 protein 0.002 0.0287 0.0287
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0011 0.0112 0.0112
Toxoplasma gondii hypothetical protein 0.0053 0.0988 0.8275
Echinococcus multilocularis axis inhibition protein axin 0.002 0.0287 0.0405
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0011 0.0112 0.0112
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.001 0.0092 0.013
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0011 0.0112 0.0158
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0016 0.0209 0.0295
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0011 0.0112 0.0112
Brugia malayi Nuclear hormone receptor-like 1 0.0011 0.0112 0.0112
Schistosoma mansoni hypothetical protein 0.0016 0.0209 0.0541
Schistosoma mansoni regulator of G protein signaling 0.002 0.0287 0.0743
Brugia malayi hypothetical protein 0.002 0.0287 0.0287
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0287 0.0553
Brugia malayi hypothetical protein 0.0239 0.4923 0.4923
Echinococcus multilocularis regulator of G protein signaling 7 0.002 0.0287 0.0405
Echinococcus multilocularis Regulator of G protein signaling 20 0.002 0.0287 0.0405
Schistosoma mansoni RAR-like nuclear receptor 0.0011 0.0112 0.029
Entamoeba histolytica hypothetical protein 0.002 0.0287 0.5
Mycobacterium leprae Probable lipase LipE 0.0036 0.0643 0.5
Schistosoma mansoni hypothetical protein 0.0016 0.0209 0.0541
Echinococcus granulosus beta-adrenergic receptor kinase 0.0189 0.3859 0.5445
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0011 0.0112 0.0158
Schistosoma mansoni regulator of G protein signaling 0.002 0.0287 0.0743
Mycobacterium ulcerans hypothetical protein 0.0172 0.3511 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0011 0.0112 0.0112
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.002 0.0287 0.0287
Loa Loa (eye worm) hypothetical protein 0.0034 0.0597 0.0597
Echinococcus granulosus survival motor neuron protein 1 0.0239 0.4923 0.6945
Schistosoma mansoni survival motor neuron protein 0.0049 0.0904 0.2343
Echinococcus granulosus axis inhibition protein axin 0.002 0.0287 0.0405
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0056 0.1058 0.0676
Onchocerca volvulus 0.0036 0.0643 0.0537
Brugia malayi photoreceptor-specific nuclear receptor 0.0011 0.0112 0.0112
Loa Loa (eye worm) hypothetical protein 0.0036 0.0643 0.0643
Schistosoma mansoni regulator of G protein signaling 0.002 0.0287 0.0743
Loa Loa (eye worm) hypothetical protein 0.002 0.0287 0.0287
Brugia malayi Regulator of G protein signaling domain containing protein 0.002 0.0287 0.0287
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0011 0.0112 0.0158
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0011 0.0112 0.0112
Brugia malayi nuclear hormone receptor 0.0011 0.0112 0.0112
Mycobacterium tuberculosis Conserved hypothetical protein 0.0172 0.3511 0.6924
Loa Loa (eye worm) hypothetical protein 0.0239 0.4923 0.4923
Echinococcus multilocularis FTZ F1 alpha 0.0011 0.0112 0.0158
Loa Loa (eye worm) hypothetical protein 0.002 0.0287 0.0287
Entamoeba histolytica hypothetical protein 0.002 0.0287 0.5
Echinococcus granulosus GPCR family 2 0.0016 0.0209 0.0295
Schistosoma mansoni lozenge 0.006 0.1145 0.2966
Echinococcus multilocularis cpg binding protein 0.0031 0.0537 0.0758
Echinococcus multilocularis G protein coupled receptor kinase 1 0.0169 0.3447 0.4863
Loa Loa (eye worm) hypothetical protein 0.005 0.093 0.093
Schistosoma mansoni cpg binding protein 0.003 0.0501 0.1299
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0189 0.3859 0.3859
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0008 0.0054 0.0076
Echinococcus multilocularis regulator of G protein signaling 7 0.002 0.0287 0.0405
Loa Loa (eye worm) hypothetical protein 0.048 1 1
Echinococcus multilocularis tumor protein p63 0.0342 0.7088 1
Schistosoma mansoni axis inhibition protein axin 0.002 0.0287 0.0743
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0036 0.0643 0.0643
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0287 0.0553
Brugia malayi Calcitonin receptor-like protein seb-1 0.005 0.0931 0.0931
Brugia malayi Pre-SET motif family protein 0.0031 0.0521 0.0521
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0016 0.0209 0.0295
Loa Loa (eye worm) hypothetical protein 0.0036 0.0643 0.0643
Brugia malayi ecdysteroid receptor 0.0011 0.0112 0.0112
Echinococcus granulosus expressed protein 0.002 0.0287 0.0405
Brugia malayi regulator of G-protein signaling egl-10 0.002 0.0287 0.0287
Echinococcus granulosus regulator of G protein signaling 3 0.002 0.0287 0.0405
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0064 0.1228 0.3181
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0287 0.0553
Onchocerca volvulus 0.0036 0.0643 0.0537
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0008 0.0054 0.0139
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0011 0.0112 0.0112
Echinococcus multilocularis thyroid hormone receptor alpha 0.0151 0.307 0.4331
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0011 0.0112 0.0112
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0011 0.0112 0.0112
Echinococcus granulosus G protein coupled receptor kinase 1 0.0169 0.3447 0.4863
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.002 0.0287 0.0405
Schistosoma mansoni axis inhibition protein axin 0.002 0.0287 0.0743
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0011 0.0112 0.0112
Loa Loa (eye worm) hypothetical protein 0.0031 0.0521 0.0521
Brugia malayi PXA domain containing protein 0.002 0.0287 0.0287
Brugia malayi PXA domain containing protein 0.002 0.0287 0.0287
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0011 0.0112 0.0158
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0011 0.0112 0.0158
Echinococcus granulosus FTZ F1 alpha 0.0011 0.0112 0.0158
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0011 0.0112 0.0158
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.021 0.4299 0.4299
Onchocerca volvulus 0.0049 0.0904 0.0801
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0011 0.0112 0.029
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0287 0.0553
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0046 0.0845 0.033
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0016 0.0209 0.0209
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0011 0.0112 0.0112
Brugia malayi latrophilin 2 splice variant baaae 0.0034 0.0597 0.0597
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0643 0.1281
Schistosoma mansoni thyroid hormone receptor 0.0151 0.307 0.7954

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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