Detailed information for compound 697567

Basic information

Technical information
  • TDR Targets ID: 697567
  • Name: 2-ethoxy-N-[4-([1,2,4]triazolo[3,4-f]pyridazi n-6-yl)phenyl]acetamide
  • MW: 297.312 | Formula: C15H15N5O2
  • H donors: 1 H acceptors: 4 LogP: 0.83 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCOCC(=O)Nc1ccc(cc1)c1ccc2n(n1)cnn2
  • InChi: 1S/C15H15N5O2/c1-2-22-9-15(21)17-12-5-3-11(4-6-12)13-7-8-14-18-16-10-20(14)19-13/h3-8,10H,2,9H2,1H3,(H,17,21)
  • InChiKey: NKAQWENIDORNJC-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 2-ethoxy-N-[4-([1,2,4]triazolo[3,4-f]pyridazin-6-yl)phenyl]ethanamide
  • ZINC04377136

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis DNA polymerase eta, putative 0.0019 0.0179 0.0382
Brugia malayi PHD-finger family protein 0.0029 0.0395 0.0573
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0096 0.1838 0.1872
Plasmodium vivax calcium-dependent protein kinase, putative 0.0034 0.05 0.0495
Brugia malayi Major Facilitator Superfamily protein 0.0016 0.01 0.0142
Entamoeba histolytica hypothetical protein 0.0036 0.0541 0.2074
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0025 0.0299 0.0961
Brugia malayi hypothetical protein 0.0237 0.4873 0.7111
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0039 0.0612 0.2459
Toxoplasma gondii lysine-tRNA ligase 0.0025 0.0299 0.0308
Echinococcus multilocularis solute carrier family 22 0.0016 0.01 0.0102
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0034 0.0499 0.0509
Schistosoma mansoni protein kinase 0.0034 0.0499 0.0567
Leishmania major DNA polymerase eta, putative 0.0019 0.0179 0.081
Loa Loa (eye worm) hypothetical protein 0.0016 0.01 0.0142
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0016 0.0115 0.011
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0039 0.0604 0.7387
Loa Loa (eye worm) hypothetical protein 0.0032 0.0462 0.0671
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0016 0.0115 0.0108
Loa Loa (eye worm) hypothetical protein 0.0019 0.0179 0.0258
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0034 0.0484 0.1855
Giardia lamblia Prolyl-tRNA synthetase 0.0034 0.0484 0.7516
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0179 0.177
Leishmania major trypanothione reductase 0.0047 0.0783 0.6991
Schistosoma mansoni sugar transporter 0.0016 0.01 0.009
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0018 0.0158 0.1482
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.0016 0.01 0.0691
Plasmodium vivax CDK-related protein kinase 6, putative 0.0474 1 1
Schistosoma mansoni jumonji/arid domain-containing protein 0.0037 0.0563 0.0643
Loa Loa (eye worm) PHD-finger family protein 0.0029 0.0395 0.0573
Plasmodium falciparum protein kinase 7 0.0316 0.6577 0.6575
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0017 0.012 0.0972
Loa Loa (eye worm) hypothetical protein 0.0034 0.0484 0.0704
Echinococcus granulosus Niemann Pick C1 protein 0.0148 0.2965 0.3019
Trypanosoma brucei glucose transporter 1E 0.0035 0.0509 0.6265
Echinococcus granulosus lysine specific demethylase 5A 0.0037 0.0563 0.0573
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0034 0.0499 0.0725
Treponema pallidum NADH oxidase 0.0016 0.0115 0.6963
Brugia malayi Niemann-Pick C1 protein precursor 0.0104 0.2003 0.2921
Trypanosoma cruzi hexose transporter, putative 0.0035 0.0509 0.5988
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0039 0.0612 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0179 0.177
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0509 0.1973
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0039 0.0612 0.2468
Schistosoma mansoni hypothetical protein 0.0112 0.2173 0.2565
Brugia malayi major facilitator superfamily protein 0.0016 0.01 0.0142
Schistosoma mansoni hypothetical protein 0.0043 0.0688 0.0792
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0018 0.0158 0.0257
Giardia lamblia Lysyl-tRNA synthetase 0.0025 0.0299 0.3895
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0034 0.0499 0.0509
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0034 0.0484 0.0493
Schistosoma mansoni DNA polymerase eta 0.0019 0.0179 0.0184
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0039 0.0612 0.7665
Brugia malayi hypothetical protein 0.0036 0.0541 0.0786
Brugia malayi Latrophilin receptor protein 2 0.0032 0.0462 0.0671
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.0115 0.022
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0017 0.0119 0.0112
Echinococcus granulosus solute carrier family 22 0.0016 0.01 0.0102
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0061 0.1077 0.1096
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0034 0.0499 0.0509
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0395 0.0456
Entamoeba histolytica hypothetical protein 0.0036 0.0541 0.2074
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.1077 1
Schistosoma mansoni ap endonuclease 0.0018 0.0158 0.0159
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0179 0.177
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.0115 0.022
Echinococcus multilocularis expressed conserved protein 0.0098 0.1867 0.1901
Echinococcus granulosus synaptic vesicle 2 protein 0.0016 0.01 0.0102
Loa Loa (eye worm) hypothetical protein 0.0016 0.01 0.0142
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0039 0.0612 0.7491
Mycobacterium ulcerans sugar transporter 0.0016 0.01 0.0788
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0179 0.177
Trypanosoma brucei unspecified product 0.0019 0.0179 0.177
Schistosoma mansoni hypothetical protein 0.007 0.1275 0.1494
Loa Loa (eye worm) hypothetical protein 0.0016 0.01 0.0142
Echinococcus granulosus neuropeptide s receptor 0.0466 0.9821 1
Schistosoma mansoni cpg binding protein 0.0028 0.0367 0.0409
Schistosoma mansoni mixed-lineage leukemia protein mll 0.006 0.1047 0.1221
Trypanosoma cruzi hexose transporter, putative 0.0035 0.0509 0.5988
Plasmodium falciparum proline--tRNA ligase 0.0039 0.0604 0.06
Onchocerca volvulus 0.0328 0.6851 1
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0723 0.3005
Brugia malayi hypothetical protein 0.0027 0.0349 0.0506
Brugia malayi hypothetical protein 0.0018 0.014 0.0201
Trypanosoma brucei glucose transporter, putative 0.0035 0.0509 0.6265
Loa Loa (eye worm) bifunctional aminoacyl-tRNA synthetase 0.0014 0.0058 0.0081
Giardia lamblia DINP protein human, muc B family 0.0019 0.0179 0.1546
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0179 0.1158
Trypanosoma cruzi hexose transporter, putative 0.0019 0.017 0.1021
Trypanosoma brucei glucose transporter, putative 0.0035 0.0509 0.6265
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0367 0.0533
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0017 0.012 0.0123
Echinococcus multilocularis solute carrier family 22 0.0016 0.01 0.0102
Entamoeba histolytica deoxycytidyl transferase, putative 0.0019 0.0179 0.0114
Loa Loa (eye worm) hypothetical protein 0.0039 0.0612 0.0889
Echinococcus multilocularis ubiquitin specific protease 41 0.0039 0.0612 0.0623
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0019 0.0179 0.0351
Schistosoma mansoni hypothetical protein 0.0032 0.0462 0.0522
Brugia malayi hypothetical protein 0.0123 0.2426 0.3539
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.012 0.0301
Toxoplasma gondii thioredoxin reductase 0.0047 0.0783 0.1054
Trichomonas vaginalis glutathione reductase, putative 0.0016 0.0115 0.0072
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0108 0.2092 0.8781
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.012 0.2353 1
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0179 0.1158
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0179 0.177
Trypanosoma cruzi trypanothione reductase, putative 0.0016 0.0115 0.022
Echinococcus multilocularis cpg binding protein 0.003 0.0402 0.0409
Echinococcus granulosus PHD finger protein rhinoceros 0.0029 0.0395 0.0402
Loa Loa (eye worm) sugar transporter 0.0016 0.01 0.0142
Echinococcus granulosus General substrate transporter 0.0096 0.1834 0.1867
Schistosoma mansoni hypothetical protein 0.0043 0.0688 0.0792
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0034 0.0484 0.0704
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0018 0.0158 0.0849
Echinococcus granulosus expressed conserved protein 0.0098 0.1867 0.1901
Schistosoma mansoni jumonji/arid domain-containing protein 0.0037 0.0563 0.0643
Giardia lamblia NADH oxidase lateral transfer candidate 0.0016 0.0115 0.0293
Echinococcus granulosus neuropeptide receptor A26 0.0466 0.9821 1
Trichomonas vaginalis sugar transporter, putative 0.0035 0.0509 0.1973
Loa Loa (eye worm) sugar transporter 0.0112 0.2173 0.317
Toxoplasma gondii facilitative glucose transporter GT1 0.0112 0.2173 0.3201
Leishmania major glucose transporter, lmgt1 0.0035 0.0509 0.4186
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0112 0.2173 0.2213
Loa Loa (eye worm) glutathione reductase 0.0047 0.0783 0.1139
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.0349 0.3646
Trypanosoma brucei glucose transporter 2A 0.0035 0.0509 0.6265
Loa Loa (eye worm) hypothetical protein 0.0016 0.01 0.0142
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0039 0.0612 0.0701
Echinococcus multilocularis sterol regulatory element binding protein 0.0045 0.0723 0.0736
Echinococcus granulosus Protein patched homolog 1 0.0045 0.0723 0.0736
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0034 0.05 0.0495
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0016 0.0115 0.0164
Brugia malayi Cam kinase protein 1 0.0034 0.0499 0.0725
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0115 0.0896
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.012 0.0972
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.0115 0.0154
Onchocerca volvulus Alhambra homolog 0.0029 0.0395 0.0437
Leishmania major glucose transporter, lmgt3 0.0035 0.0509 0.4186
Loa Loa (eye worm) hypothetical protein 0.0027 0.0349 0.0505
Loa Loa (eye worm) hypothetical protein 0.0016 0.01 0.0142
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0032 0.0462 0.047
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0034 0.0499 0.6137
Echinococcus multilocularis dna polymerase kappa 0.0019 0.0179 0.0182
Echinococcus granulosus calcium dependent protein kinase 0.0032 0.0454 0.0462
Echinococcus multilocularis PHD finger protein rhinoceros 0.0029 0.0395 0.0402
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0108 0.2092 0.8845
Leishmania major glucose transporter, lmgt2 0.0035 0.0509 0.4186
Leishmania major glucose transporter/membrane transporter D2, putative 0.0035 0.0509 0.4186
Plasmodium vivax thioredoxin reductase, putative 0.0047 0.0783 0.0778
Schistosoma mansoni cpg binding protein 0.003 0.0402 0.0451
Loa Loa (eye worm) hypothetical protein 0.0016 0.01 0.0142
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0018 0.0158 1
Brugia malayi Major Facilitator Superfamily protein 0.0016 0.01 0.0142
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0016 0.0115 0.2587
Loa Loa (eye worm) hypothetical protein 0.0034 0.0499 0.0725
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.1077 1
Loa Loa (eye worm) hypothetical protein 0.0027 0.0349 0.0506
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0049 0.0828 0.0843
Schistosoma mansoni sugar transporter 0.0016 0.01 0.009
Trypanosoma brucei THT1 - hexose transporter, putative 0.0035 0.0509 0.6265
Brugia malayi Isocitrate dehydrogenase 0.0017 0.012 0.0172
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0039 0.0612 0.0623
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0039 0.0604 0.5164
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0034 0.0499 0.0509
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0016 0.01 0.0102
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.0158 0.0153
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.012 0.0211
Mycobacterium ulcerans integral membrane transport protein 0.0016 0.01 0.0788
Echinococcus granulosus solute carrier family 22 0.0016 0.01 0.0102
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.012 0.0123
Plasmodium vivax lysine--tRNA ligase, putative 0.0025 0.0299 0.0294
Plasmodium vivax hexose transporter 0.0112 0.2173 0.2169
Schistosoma mansoni patched 1 0.0045 0.0723 0.0834
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0049 0.0828 0.0843
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0018 0.0158 0.0849
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0115 0.022
Brugia malayi lysyl-tRNA synthetase 0.0025 0.0299 0.0433
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0016 0.0115 0.0154
Plasmodium falciparum glutathione reductase 0.0047 0.0783 0.0778
Brugia malayi CHE-14 protein 0.0045 0.0723 0.1052
Loa Loa (eye worm) hypothetical protein 0.0055 0.0939 0.1368
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.012 0.0123
Brugia malayi F/Y-rich N-terminus family protein 0.0018 0.0153 0.022
Schistosoma mansoni hypothetical protein 0.0043 0.0688 0.0792
Schistosoma mansoni survival motor neuron protein 0.0048 0.0803 0.093
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0115 0.022
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.0158 0.0153
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0108 0.2092 0.8845
Echinococcus multilocularis protein dispatched 1 0.0051 0.0859 0.0874
Treponema pallidum exodeoxyribonuclease (exoA) 0.0018 0.0158 1
Schistosoma mansoni serine/threonine protein kinase 0.0034 0.0499 0.0567
Schistosoma mansoni ap endonuclease 0.0018 0.0158 0.0159
Loa Loa (eye worm) hypothetical protein 0.0237 0.4873 0.7111
Echinococcus granulosus jumonji domain containing protein 0.0041 0.0643 0.0655
Brugia malayi exodeoxyribonuclease III family protein 0.0018 0.0158 0.0227
Loa Loa (eye worm) hypothetical protein 0.0029 0.0395 0.0573
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0017 0.012 0.0091
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0039 0.0612 0.5237
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0034 0.0499 0.0509
Echinococcus granulosus thioredoxin glutathione reductase 0.0047 0.0783 0.0797
Echinococcus multilocularis Niemann Pick C1 protein 0.0104 0.2003 0.2039
Echinococcus granulosus survival motor neuron protein 1 0.0237 0.4873 0.4961
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0025 0.0299 0.2667
Trypanosoma brucei glucose transporter, putative 0.0035 0.0509 0.6265
Echinococcus multilocularis solute carrier family 22 0.0016 0.01 0.0102
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.0021 0.0218 0.0524
Echinococcus multilocularis synaptic vesicle 2 protein 0.0016 0.01 0.0102
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0179 0.177
Plasmodium falciparum mitogen-activated protein kinase 2 0.0181 0.3659 0.3656
Loa Loa (eye worm) hypothetical protein 0.0328 0.6851 1
Echinococcus granulosus Niemann Pick C1 protein 0.0104 0.2003 0.2039
Toxoplasma gondii LsmAD domain-containing protein 0.0027 0.0349 0.0384
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0112 0.2173 0.2213
Schistosoma mansoni lysyl-tRNA synthetase 0.0025 0.0299 0.0328
Schistosoma mansoni sugar transporter 0.0016 0.01 0.009
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0016 0.0115 0.0896
Echinococcus granulosus Sugar transporter ERD6 protein 0.0016 0.01 0.0102
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0036 0.0541 0.055
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0032 0.0462 0.047
Leishmania major DNA polymerase kappa, putative 0.0019 0.0179 0.081
Onchocerca volvulus Huntingtin homolog 0.0123 0.2426 0.3446
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.0115 0.0154
Echinococcus granulosus cpg binding protein 0.003 0.0402 0.0409
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0034 0.05 0.0495
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0018 0.0158 0.0594
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0034 0.0499 0.0725
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0179 0.177
Toxoplasma gondii protein kinase, putative 0.0316 0.6577 1
Trypanosoma cruzi DNA polymerase eta, putative 0.0019 0.0179 0.1158
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0017 0.012 0.0116
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.0158 0.028
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0017 0.012 0.0116
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0061 0.1077 1
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0179 0.177
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0034 0.0499 0.0509
Brugia malayi Bromodomain containing protein 0.0029 0.0395 0.0573
Loa Loa (eye worm) hypothetical protein 0.0016 0.01 0.0142
Entamoeba histolytica hypothetical protein 0.0036 0.0541 0.2074
Brugia malayi jmjC domain containing protein 0.0096 0.1838 0.268
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0049 0.0828 0.1206
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0049 0.0828 0.096
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0049 0.0828 0.1206
Trichomonas vaginalis CAMK family protein kinase 0.0034 0.0499 0.1927
Toxoplasma gondii isocitrate dehydrogenase 0.0017 0.012 0.0032
Brugia malayi jmjC domain containing protein 0.0037 0.0563 0.0818
Giardia lamblia PHD finger protein 15 0.0029 0.0395 0.5767
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0048 0.0803 0.1169
Brugia malayi Thioredoxin reductase 0.0047 0.0783 0.1139
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0019 0.0179 0.0182
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0179 0.0258
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.0158 0.028
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0181 0.3659 0.3656
Schistosoma mansoni hypothetical protein 0.0179 0.362 0.4293
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0395 0.0456
Schistosoma mansoni jumonji domain containing protein 0.0076 0.1411 0.1656
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0061 0.1077 0.1096
Plasmodium falciparum calcium-dependent protein kinase 2 0.0034 0.05 0.0495
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0108 0.2092 0.8845
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.012 0.0123
Echinococcus multilocularis dna polymerase eta 0.0019 0.0179 0.0182
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0612 0.2468
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.0349 0.0344
Trypanosoma brucei PAB1-binding protein , putative 0.0027 0.0349 0.4086
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0025 0.0299 0.3407
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0039 0.0604 0.0779
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0509 0.1973
Loa Loa (eye worm) isocitrate dehydrogenase 0.0017 0.012 0.0172
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0179 0.177
Echinococcus granulosus dna polymerase kappa 0.0019 0.0179 0.0182
Echinococcus granulosus dna polymerase eta 0.0019 0.0179 0.0182
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0016 0.01 0.0095
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0034 0.05 0.0495
Schistosoma mansoni hypothetical protein 0.04 0.84 1
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0012 0.0025 0.0025
Trypanosoma brucei glucose transporter, putative 0.0035 0.0509 0.6265
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0032 0.0462 0.047
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0019 0.0179 0.081
Brugia malayi hypothetical protein 0.0328 0.6851 1
Trypanosoma brucei sugar transporter, putative 0.0016 0.01 0.0691
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0049 0.0828 0.0843
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0115 0.0896
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0018 0.0158 0.0227
Leishmania major protein kinase, putative 0.0034 0.0499 0.4089
Brugia malayi MH2 domain containing protein 0.0126 0.2479 0.3617
Trypanosoma brucei glucose transporter, putative 0.0035 0.0509 0.6265
Loa Loa (eye worm) hypothetical protein 0.0016 0.01 0.0142
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0034 0.05 0.0617
Mycobacterium tuberculosis Probable dehydrogenase 0.0108 0.2092 0.8845
Toxoplasma gondii exonuclease III APE 0.0018 0.0158 0.009
Loa Loa (eye worm) hypothetical protein 0.0016 0.01 0.0142
Schistosoma mansoni hypothetical protein 0.0048 0.0803 0.093
Schistosoma mansoni aldehyde dehydrogenase 0.0061 0.1077 0.1256
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0018 0.0158 0.1335
Brugia malayi CXXC zinc finger family protein 0.0028 0.0367 0.0533
Toxoplasma gondii isocitrate dehydrogenase 0.0017 0.012 0.0032
Trypanosoma brucei THT1 - hexose transporter, putative 0.0035 0.0509 0.6265
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0016 0.0115 0.0023
Brugia malayi Sugar transporter family protein 0.0016 0.01 0.0142
Trypanosoma brucei trypanothione reductase 0.0047 0.0783 1
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0012 0.0021 0.0027
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0108 0.2092 0.8845
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0029 0.0395 0.0442
Plasmodium falciparum phd finger protein, putative 0.0029 0.0395 0.039
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0112 0.2173 0.2213
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0179 0.1158
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0179 0.1534
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0115 0.022
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0179 0.177
Loa Loa (eye worm) thioredoxin reductase 0.0047 0.0783 0.1139
Trichomonas vaginalis glucose transporter, putative 0.0035 0.0509 0.1973
Echinococcus granulosus peregrin 0.0029 0.0395 0.0402
Loa Loa (eye worm) MH2 domain-containing protein 0.0126 0.2479 0.3617
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0061 0.1077 0.4337
Trichomonas vaginalis sugar transporter, putative 0.0035 0.0509 0.1973
Brugia malayi latrophilin 2 splice variant baaae 0.007 0.1275 0.1859
Schistosoma mansoni glucose transporter 0.0016 0.01 0.009
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0034 0.0484 0.0549
Loa Loa (eye worm) transcription factor SMAD2 0.0126 0.2479 0.3617
Echinococcus multilocularis protein patched 0.0045 0.0723 0.0736
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0115 0.022
Echinococcus multilocularis isocitrate dehydrogenase 0.0017 0.012 0.0123
Onchocerca volvulus 0.0048 0.0803 0.1042
Toxoplasma gondii aldehyde dehydrogenase 0.0061 0.1077 0.1508
Schistosoma mansoni lysyl-tRNA synthetase 0.0025 0.0299 0.0328
Plasmodium falciparum glutathione reductase 0.0016 0.0115 0.011
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0019 0.0179 0.0258
Loa Loa (eye worm) jmjC domain-containing protein 0.0037 0.0563 0.0818
Schistosoma mansoni hypothetical protein 0.0032 0.0462 0.0522
Loa Loa (eye worm) major facilitator superfamily transporter 0.0016 0.01 0.0142
Brugia malayi Sugar transporter family protein 0.0112 0.2173 0.317
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0012 0.0025 0.0025
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0016 0.01 0.009
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0016 0.0115 0.0067
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0034 0.0484 0.0549
Trypanosoma cruzi hexose transporter, putative 0.0035 0.0509 0.5988
Echinococcus multilocularis neuropeptide s receptor 0.0466 0.9821 1
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0103 0.1977 0.2882
Loa Loa (eye worm) hypothetical protein 0.0123 0.2426 0.3539
Echinococcus granulosus GPCR family 2 0.0032 0.0462 0.047
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0016 0.0115 0.0896
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0025 0.0299 0.2918
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0039 0.0612 0.0623
Echinococcus multilocularis Niemann Pick C1 protein 0.0148 0.2965 0.3019
Schistosoma mansoni transcription factor LCR-F1 0.0036 0.0541 0.0616
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0016 0.0115 0.011
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0039 0.0612 0.0701
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0017 0.012 0.0123
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0047 0.0783 0.3032
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0039 0.0612 0.7491
Echinococcus granulosus geminin 0.0179 0.362 0.3686
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0179 0.177
Schistosoma mansoni protein kinase 0.0034 0.0499 0.0567
Trypanosoma cruzi hexose transporter 0.0035 0.0509 0.5988
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0012 0.0021 0.0027
Loa Loa (eye worm) jmjC domain-containing protein 0.0061 0.107 0.1559
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0018 0.0158 0.0161
Echinococcus multilocularis peregrin 0.0029 0.0395 0.0402
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0019 0.0179 0.0184
Echinococcus granulosus sterol regulatory element binding protein 0.0045 0.0723 0.0736
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0025 0.0299 0.2667
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.012 0.2353 1
Loa Loa (eye worm) hypothetical protein 0.0016 0.01 0.0142
Brugia malayi hypothetical protein 0.0016 0.01 0.0142
Schistosoma mansoni hypothetical protein 0.0029 0.0395 0.0442
Loa Loa (eye worm) hypothetical protein 0.0045 0.0723 0.1052
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0181 0.3659 0.5495
Schistosoma mansoni cpg binding protein 0.003 0.0402 0.0451
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0039 0.0612 0.0623
Trypanosoma brucei DNA polymerase eta, putative 0.0019 0.0179 0.177
Loa Loa (eye worm) hypothetical protein 0.0034 0.0484 0.0704
Echinococcus multilocularis solute carrier family 22 0.0016 0.01 0.0102
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0016 0.0115 0.0929
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0019 0.0179 0.0382
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.1077 1
Trichomonas vaginalis conserved hypothetical protein 0.0112 0.2173 1
Echinococcus multilocularis geminin 0.0179 0.362 0.3686
Mycobacterium tuberculosis Conserved hypothetical protein 0.0019 0.0179 0.0351
Schistosoma mansoni glucose transport protein 0.0112 0.2173 0.2565
Echinococcus granulosus solute carrier family 22 0.0016 0.01 0.0102
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0032 0.0462 0.0671
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0039 0.0612 0.2468
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0039 0.0612 0.0889
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0179 0.177
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0034 0.0499 0.0509
Loa Loa (eye worm) hypothetical protein 0.007 0.1275 0.1859
Trichomonas vaginalis mercuric reductase, putative 0.0016 0.0115 0.0072
Schistosoma mansoni hypothetical protein 0.0036 0.0541 0.0616
Loa Loa (eye worm) hypothetical protein 0.0016 0.01 0.0142
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0032 0.0462 0.047
Entamoeba histolytica protein kinase, putative 0.0034 0.0499 0.1851
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0112 0.2173 0.2213
Plasmodium falciparum hexose transporter 0.0112 0.2173 0.2169
Echinococcus multilocularis lysine specific demethylase 5A 0.0036 0.0528 0.0538
Plasmodium vivax sugar transporter, putative 0.0016 0.01 0.0095
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0034 0.0499 0.0725
Schistosoma mansoni hypothetical protein 0.0032 0.0462 0.0522
Brugia malayi hypothetical protein 0.0016 0.01 0.0142
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.012 0.2353 1
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0016 0.0115 0.0154
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.0349 0.0344
Plasmodium falciparum thioredoxin reductase 0.0047 0.0783 0.0778
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0016 0.0115 0.0929
Trypanosoma cruzi trypanothione reductase, putative 0.0047 0.0783 1
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0022 0.0233 0.0641
Brugia malayi glutathione reductase 0.0047 0.0783 0.1139
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0103 0.1977 0.2882
Plasmodium falciparum calcium-dependent protein kinase 4 0.0034 0.05 0.0495
Plasmodium falciparum lysine--tRNA ligase 0.0025 0.0299 0.0294
Trypanosoma brucei glucose transporter, putative 0.0035 0.0509 0.6265
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0112 0.2173 0.2213
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0034 0.05 0.0617
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0039 0.0612 0.0623
Echinococcus multilocularis General substrate transporter 0.0096 0.1834 0.1867
Loa Loa (eye worm) major facilitator superfamily transporter 0.0016 0.01 0.0142
Echinococcus multilocularis survival motor neuron protein 1 0.0237 0.4873 0.4961
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0018 0.0158 0.0161
Plasmodium vivax ataxin-2 like protein, putative 0.0027 0.0349 0.0344
Plasmodium falciparum thioredoxin reductase 0.0016 0.0115 0.011
Trichomonas vaginalis sugar transporter, putative 0.0035 0.0509 0.1973
Brugia malayi major facilitator superfamily protein 0.0016 0.01 0.0142
Plasmodium falciparum calcium-dependent protein kinase 1 0.0034 0.05 0.0495
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0016 0.0115 0.0117
Trichomonas vaginalis glucose transporter, putative 0.0035 0.0509 0.1973
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0049 0.0828 0.0843
Schistosoma mansoni hypothetical protein 0.0032 0.0462 0.0522
Loa Loa (eye worm) hypothetical protein 0.0104 0.2003 0.2921
Entamoeba histolytica protein kinase, putative 0.0034 0.0499 0.1851
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0039 0.0604 0.7387
Echinococcus granulosus lysyl tRNA synthetase 0.0025 0.0299 0.0305
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0034 0.0484 0.177
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0039 0.0604 0.7567
Echinococcus multilocularis lysyl tRNA synthetase 0.0025 0.0299 0.0305
Echinococcus granulosus solute carrier family 22 0.0016 0.01 0.0102
Leishmania major hypothetical protein, conserved 0.0027 0.0349 0.2549
Schistosoma mansoni protein kinase 0.0034 0.0499 0.0567
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0034 0.0484 0.0704
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0019 0.0179 0.0182
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0016 0.0115 0.2587
Entamoeba histolytica hypothetical protein 0.0036 0.0541 0.2074
Schistosoma mansoni sugar transporter 0.0016 0.01 0.009
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0049 0.0828 0.096
Plasmodium vivax hypothetical protein, conserved 0.0029 0.0395 0.039
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.0016 0.01 0.0788
Brugia malayi isocitrate dehydrogenase 0.0017 0.012 0.0172
Brugia malayi hypothetical protein 0.0016 0.01 0.0142
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0039 0.0604 0.5164
Loa Loa (eye worm) hypothetical protein 0.0016 0.01 0.0142
Loa Loa (eye worm) hypothetical protein 0.0016 0.01 0.0142
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0016 0.0115 0.011
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0104 0.2003 1
Trypanosoma brucei glucose transporter, putative 0.0035 0.0509 0.6265
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0034 0.0484 0.0493
Loa Loa (eye worm) hypothetical protein 0.0016 0.01 0.0142
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0045 0.0723 0.1052
Brugia malayi Major Facilitator Superfamily protein 0.0016 0.01 0.0142
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0096 0.1838 0.1872
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0016 0.0115 0.0929
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0034 0.0484 0.1248
Plasmodium falciparum calcium-dependent protein kinase 3 0.0034 0.05 0.0495
Plasmodium vivax proline--tRNA ligase, putative 0.0039 0.0604 0.06
Brugia malayi Calcitonin receptor-like protein seb-1 0.0103 0.1977 0.2882
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0115 0.022
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0017 0.012 0.0115
Trypanosoma brucei glucose transporter, putative 0.0035 0.0509 0.6265
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0021 0.0218 0.0524
Schistosoma mansoni glucose transport protein 0.0112 0.2173 0.2565
Echinococcus multilocularis neuropeptide receptor A26 0.0466 0.9821 1
Echinococcus multilocularis dnaJ subfamily B 0.04 0.84 0.8553
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0112 0.2173 0.2213
Toxoplasma gondii NADPH-glutathione reductase 0.0016 0.0115 0.0023
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0112 0.2173 0.2213
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0179 0.1534
Echinococcus multilocularis GPCR, family 2 0.0032 0.0462 0.047
Trypanosoma brucei THT1 - hexose transporter, putative 0.0035 0.0509 0.6265
Mycobacterium tuberculosis Probable oxidoreductase 0.012 0.2353 1
Loa Loa (eye worm) latrophilin receptor protein 2 0.0032 0.0462 0.0671
Loa Loa (eye worm) hypothetical protein 0.0016 0.01 0.0142
Leishmania major lysyl-tRNA synthetase, putative 0.0025 0.0299 0.204
Schistosoma mansoni hypothetical protein 0.0043 0.0688 0.0792
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0105 0.2037 0.2403
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0016 0.0115 0.3485
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0049 0.0828 0.096
Schistosoma mansoni hypothetical protein 0.0179 0.362 0.4293
Loa Loa (eye worm) hypothetical protein 0.0025 0.0299 0.0433
Loa Loa (eye worm) hypothetical protein 0.0103 0.1977 0.2882
Schistosoma mansoni aldehyde dehydrogenase 0.0061 0.1077 0.1256
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0179 0.177
Loa Loa (eye worm) hypothetical protein 0.0123 0.2426 0.3539
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0016 0.0115 0.0117
Echinococcus multilocularis jumonji domain containing protein 0.0041 0.0643 0.0655
Schistosoma mansoni terminal deoxycytidyl transferase 0.0019 0.0179 0.0184
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0034 0.05 0.0617
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0016 0.0115 0.011
Plasmodium vivax glutathione reductase, putative 0.0047 0.0783 0.0778
Onchocerca volvulus Huntingtin homolog 0.0123 0.2426 0.3446
Mycobacterium tuberculosis Probable reductase 0.0108 0.2092 0.8845
Chlamydia trachomatis lysine--tRNA ligase 0.0025 0.0299 1
Brugia malayi Sugar transporter family protein 0.0016 0.01 0.0142
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0018 0.0158 0.1134
Toxoplasma gondii histone lysine methyltransferase SET1 0.0053 0.091 0.1251
Loa Loa (eye worm) hypothetical protein 0.005 0.0848 0.1235
Schistosoma mansoni glucose transport protein 0.0112 0.2173 0.2565
Echinococcus granulosus dnaJ subfamily B 0.04 0.84 0.8553
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0179 0.1158
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0179 0.0258
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.0016 0.01 0.0788
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0115 0.022
Plasmodium falciparum calcium-dependent protein kinase 5 0.0034 0.05 0.0495
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0036 0.0541 0.055
Echinococcus multilocularis calcium dependent protein kinase 0.0032 0.0454 0.0462
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0034 0.0499 0.0509
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0017 0.012 0.0301
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0025 0.0299 0.038
Onchocerca volvulus 0.0028 0.0367 0.0396
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.0349 0.3646
Entamoeba histolytica hypothetical protein 0.0025 0.0299 0.0766
Echinococcus multilocularis thioredoxin glutathione reductase 0.0047 0.0783 0.0797
Echinococcus granulosus ubiquitin specific protease 41 0.0039 0.0612 0.0623
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0112 0.2173 0.2213

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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