Detailed information for compound 711139

Basic information

Technical information
  • TDR Targets ID: 711139
  • Name: 1-(2-bromo-4-methylphenyl)-3-(4-ethoxyphenyl) urea
  • MW: 349.222 | Formula: C16H17BrN2O2
  • H donors: 2 H acceptors: 1 LogP: 3.88 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCOc1ccc(cc1)NC(=O)Nc1ccc(cc1Br)C
  • InChi: 1S/C16H17BrN2O2/c1-3-21-13-7-5-12(6-8-13)18-16(20)19-15-9-4-11(2)10-14(15)17/h4-10H,3H2,1-2H3,(H2,18,19,20)
  • InChiKey: NTQMLAVEXKOZDB-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 1-(2-bromo-4-methyl-phenyl)-3-(4-ethoxyphenyl)urea
  • IVK/1639141
  • ZINC00611826

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Giardia lamblia Lysyl-tRNA synthetase 0.0046 0.0431 0.6965
Brugia malayi Sugar transporter family protein 0.0205 0.228 0.8653
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0235 0.0982
Schistosoma mansoni hypothetical protein 0.0015 0.0077 0.034
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0035 0.0306 0.5397
Loa Loa (eye worm) hypothetical protein 0.0235 0.2635 1
Schistosoma mansoni ap endonuclease 0.0018 0.0112 0.0489
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0048 0.0461 0.1748
Plasmodium vivax CDK-related protein kinase 6, putative 0.0869 1 1
Plasmodium falciparum threonine--tRNA ligase 0.0012 0.0034 0.0022
Leishmania major acetyl-CoA synthetase, putative 0.0014 0.006 0.0578
Trypanosoma brucei glucose transporter, putative 0.0063 0.0638 0.8692
Toxoplasma gondii sugar transporter ST3 0.0029 0.0235 0.0354
Echinococcus multilocularis solute carrier family 22 0.0029 0.0235 0.0628
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0235 0.0982
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0235 0.0982
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0014 0.006 0.0663
Loa Loa (eye worm) hypothetical protein 0.0029 0.0235 0.0891
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0014 0.006 0.0774
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0014 0.006 0.0615
Loa Loa (eye worm) hypothetical protein 0.0061 0.0614 0.2331
Loa Loa (eye worm) hypothetical protein 0.0035 0.0306 0.1162
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0235 0.0982
Plasmodium vivax lysine--tRNA ligase, putative 0.0046 0.0431 0.042
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0235 0.0982
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0052 0.0508 0.1927
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0014 0.006 0.0048
Entamoeba histolytica acyl-CoA synthetase, putative 0.0047 0.0444 0.609
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0205 0.228 0.61
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0235 0.0982
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0018 0.0029
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.0284 0.4981
Entamoeba histolytica threonyl-tRNA synthetase, putative 0.0012 0.0034 0.0311
Trichomonas vaginalis conserved hypothetical protein 0.0063 0.0638 0.2761
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.0029 0.0235 0.287
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0029 0.0235 0.1029
Loa Loa (eye worm) hypothetical protein 0.0063 0.0629 0.2387
Leishmania major 4-coumarate:coa ligase-like protein 0.0047 0.0444 0.5955
Onchocerca volvulus 0.0029 0.0235 0.1216
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0046 0.0431 0.5821
Trypanosoma brucei glucose transporter, putative 0.0063 0.0638 0.8692
Mycobacterium ulcerans acetyl-CoA synthetase 0.0014 0.006 0.0615
Trichomonas vaginalis antibiotic synthetase, putative 0.0014 0.006 0.0211
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0014 0.006 0.0226
Leishmania major 4-coumarate:coa ligase-like protein 0.0047 0.0444 0.5955
Loa Loa (eye worm) hypothetical protein 0.0048 0.0461 0.1748
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0235 0.0982
Loa Loa (eye worm) hypothetical protein 0.0046 0.0431 0.1637
Brugia malayi hypothetical protein 0.0029 0.0235 0.0891
Schistosoma mansoni sugar transporter 0.0029 0.0235 0.1029
Loa Loa (eye worm) hypothetical protein 0.0035 0.0306 0.1162
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0018 0.0112 0.0298
Loa Loa (eye worm) hypothetical protein 0.0061 0.0614 0.2331
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0014 0.006 0.0663
Brugia malayi Calcitonin receptor-like protein seb-1 0.0048 0.0461 0.1748
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0076 0.0788 0.119
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0026 0.0206 0.2501
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0061 0.0614 0.2331
Mycobacterium ulcerans acyl-CoA synthetase 0.0047 0.0444 0.556
Loa Loa (eye worm) hypothetical protein 0.0047 0.0444 0.1683
Entamoeba histolytica hypothetical protein 0.0071 0.0721 1
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.0039 0.0351 0.6242
Loa Loa (eye worm) oxidoreductase 0.0014 0.006 0.0226
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0048 0.0461 0.1748
Loa Loa (eye worm) sugar transporter 0.0029 0.0235 0.0891
Brugia malayi Pax transcription activation domain interacting protein 0.001 0.0012 0.0045
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0015 0.0077 0.0207
Brugia malayi Sugar transporter family protein 0.0029 0.0235 0.0891
Brugia malayi probable proline-trna synthetase - fission yeast, putative 0.0012 0.0034 0.0129
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0235 0.0982
Leishmania major lysyl-tRNA synthetase, putative 0.0046 0.0431 0.5783
Giardia lamblia Hexose transporter 0.0029 0.0235 0.37
Echinococcus multilocularis solute carrier family 22 0.0029 0.0235 0.0628
Plasmodium falciparum lysine--tRNA ligase 0.0046 0.0431 0.042
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.0112 0.0439
Trypanosoma brucei THT1 - hexose transporter, putative 0.0063 0.0638 0.8692
Echinococcus granulosus survival motor neuron protein 1 0.0235 0.2635 0.7049
Echinococcus granulosus peptidase Clp S14 family 0.005 0.0482 0.129
Entamoeba histolytica acyl-coA synthetase, putative 0.0047 0.0444 0.609
Loa Loa (eye worm) hypothetical protein 0.0029 0.0235 0.0891
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0331 0.3745 0.5655
Schistosoma mansoni serine/threonine protein kinase 0.0063 0.0629 0.2758
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0014 0.006 0.0774
Toxoplasma gondii transporter, major facilitator family protein 0.0029 0.0235 0.0354
Schistosoma mansoni sugar transporter 0.0029 0.0235 0.1029
Brugia malayi Cam kinase protein 1 0.0063 0.0629 0.2387
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0014 0.006 0.0615
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0061 0.0614 0.2693
Giardia lamblia Glycyl-tRNA synthetase 0.0012 0.0034 0.0367
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0014 0.006 0.0615
Brugia malayi hypothetical protein 0.0071 0.0721 0.2735
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0014 0.006 0.0774
Schistosoma mansoni glucose transporter 0.0029 0.0235 0.1029
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0018 0.0112 0.1383
Echinococcus granulosus replication factor c subunit 1 0.001 0.0012 0.0032
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0076 0.0788 0.0777
Brugia malayi topoisomerase 0.001 0.0012 0.0045
Chlamydia trachomatis lysine--tRNA ligase 0.0046 0.0431 0.5402
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0331 0.3745 0.3738
Chlamydia trachomatis proline--tRNA ligase 0.0022 0.0152 0.1808
Entamoeba histolytica hypothetical protein 0.0071 0.0721 1
Loa Loa (eye worm) glycyl-tRNA synthetase 0.0012 0.0034 0.0129
Schistosoma mansoni survival motor neuron protein 0.0048 0.0458 0.2008
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0061 0.0614 0.7756
Schistosoma mansoni topbp1 0.001 0.0012 0.0052
Onchocerca volvulus 0.0029 0.0235 0.1216
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0063 0.0629 0.095
Trichomonas vaginalis sugar transport protein, putative 0.0029 0.0235 0.0982
Brugia malayi AMP-binding enzyme family protein 0.0014 0.006 0.0226
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0014 0.006 0.0774
Loa Loa (eye worm) major facilitator superfamily transporter 0.0029 0.0235 0.0891
Mycobacterium tuberculosis Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter) 0.0029 0.0235 0.4057
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0235 0.0982
Loa Loa (eye worm) hypothetical protein 0.001 0.0012 0.0045
Echinococcus multilocularis geminin 0.0169 0.186 0.4976
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0072 0.0732 1
Echinococcus granulosus glycyl tRNA synthetase 0.0012 0.0034 0.0091
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0014 0.006 0.0226
Plasmodium falciparum calcium-dependent protein kinase 4 0.0063 0.0629 0.0618
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0235 0.0982
Loa Loa (eye worm) hypothetical protein 0.0175 0.193 0.7325
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0235 0.0982
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.005 0.0482 0.6059
Schistosoma mansoni hypothetical protein 0.0048 0.0458 0.2008
Toxoplasma gondii hypothetical protein 0.0026 0.0206 0.0311
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0014 0.006 0.0663
Mycobacterium ulcerans acyl-CoA synthetase 0.0014 0.006 0.0615
Onchocerca volvulus 0.0029 0.0235 0.1216
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0014 0.006 0.0674
Toxoplasma gondii exonuclease III APE 0.0018 0.0112 0.0168
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.001 0.0012 0.0018
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0063 0.0629 0.1682
Brugia malayi AMP-binding enzyme family protein 0.0047 0.0444 0.1683
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0072 0.0732 1
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0047 0.0444 0.556
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0235 0.0982
Onchocerca volvulus Putative transporter 0.0029 0.0235 0.1216
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0029 0.0235 0.0223
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0235 0.0982
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0039 0.0351 0.6242
Trypanosoma brucei threonyl-tRNA synthetase, putative 0.0012 0.0034 0.0306
Plasmodium vivax acetyl-CoA synthetase, putative 0.0014 0.006 0.0048
Loa Loa (eye worm) latrophilin receptor protein 2 0.0015 0.0077 0.0294
Loa Loa (eye worm) hypothetical protein 0.0029 0.0235 0.0891
Echinococcus multilocularis lysyl tRNA synthetase 0.0046 0.0431 0.1154
Loa Loa (eye worm) hypothetical protein 0.0029 0.0235 0.0891
Toxoplasma gondii glycyl-tRNA synthetase 0.0012 0.0034 0.0051
Onchocerca volvulus 0.0029 0.0235 0.1216
Loa Loa (eye worm) hypothetical protein 0.0029 0.0235 0.0891
Plasmodium falciparum calcium-dependent protein kinase 1 0.0063 0.0629 0.0618
Leishmania major acetyl-CoA synthetase, putative 0.0014 0.006 0.0578
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0014 0.006 0.0615
Echinococcus granulosus calcium dependent protein kinase 0.0059 0.0584 0.1562
Trypanosoma brucei glucose transporter, putative 0.0063 0.0638 0.8692
Echinococcus granulosus lysyl tRNA synthetase 0.0046 0.0431 0.1154
Loa Loa (eye worm) hypothetical protein 0.0047 0.0444 0.1683
Onchocerca volvulus 0.0029 0.0235 0.1216
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0063 0.0629 0.0618
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0076 0.0788 0.0777
Brugia malayi Probable ClpP-like protease 0.0076 0.0788 0.2992
Loa Loa (eye worm) hypothetical protein 0.0012 0.0034 0.0129
Trypanosoma brucei glucose transporter, putative 0.0063 0.0638 0.8692
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0061 0.0614 0.2331
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0018 0.0112 0.1284
Trypanosoma brucei glucose transporter 1E 0.0063 0.0638 0.8692
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0015 0.0077 0.0207
Leishmania major glucose transporter, lmgt2 0.0063 0.0638 0.868
Trypanosoma cruzi hexose transporter, putative 0.0063 0.0638 0.8692
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0014 0.006 0.0615
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0018 0.0112 0.1406
Mycobacterium ulcerans acyl-CoA synthetase 0.0014 0.006 0.0615
Trypanosoma cruzi hexose transporter, putative 0.0029 0.0235 0.3093
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0063 0.0629 0.1682
Trypanosoma cruzi hexose transporter, putative 0.0063 0.0638 0.8692
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0076 0.0788 1
Brugia malayi Latrophilin receptor protein 2 0.0015 0.0077 0.0294
Brugia malayi Major Facilitator Superfamily protein 0.0029 0.0235 0.0891
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0015 0.0077 0.0207
Trypanosoma brucei glycyl-tRNA synthetase, putative 0.0012 0.0034 0.0306
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0018 0.0029
Mycobacterium ulcerans acyl-CoA synthetase 0.0014 0.006 0.0615
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0018 0.0112 0.1747
Trichomonas vaginalis threonyl-tRNA synthetase, putative 0.0012 0.0034 0.0097
Echinococcus granulosus GPCR family 2 0.0015 0.0077 0.0207
Brugia malayi AMP-binding enzyme family protein 0.0047 0.0444 0.1683
Onchocerca volvulus 0.0014 0.006 0.0309
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0061 0.0614 0.1643
Plasmodium vivax acyl-CoA synthetase, putative 0.0035 0.0306 0.0295
Echinococcus multilocularis calcium dependent protein kinase 0.0059 0.0584 0.1562
Trypanosoma brucei glucose transporter, putative 0.0063 0.0638 0.8692
Onchocerca volvulus 0.0029 0.0235 0.1216
Loa Loa (eye worm) hypothetical protein 0.001 0.0012 0.0045
Echinococcus multilocularis replication factor c subunit 1 0.001 0.0012 0.0032
Plasmodium falciparum acyl-CoA synthetase 0.0035 0.0306 0.0295
Schistosoma mansoni glycyl-tRNA synthetase 0.0012 0.0034 0.0149
Trichomonas vaginalis sugar transporter, putative 0.0063 0.0638 0.2761
Brugia malayi major facilitator superfamily protein 0.0029 0.0235 0.0891
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0205 0.228 0.61
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0018 0.0112 0.1655
Echinococcus multilocularis solute carrier family 22 0.0029 0.0235 0.0628
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0014 0.006 0.0663
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0175 0.193 1
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0235 0.0982
Trypanosoma cruzi hexose transporter, putative 0.0035 0.0304 0.4048
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0235 0.0982
Leishmania major threonyl-tRNA synthetase, putative 0.0012 0.0034 0.0218
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0235 0.0982
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0014 0.006 0.0663
Onchocerca volvulus 0.0047 0.0444 0.2298
Echinococcus multilocularis solute carrier family 22 0.0029 0.0235 0.0628
Brugia malayi hypothetical protein 0.015 0.1647 0.6253
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0072 0.0732 1
Loa Loa (eye worm) sugar transporter 0.0205 0.228 0.8653
Echinococcus multilocularis survival motor neuron protein 1 0.0235 0.2635 0.7049
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0014 0.006 0.0774
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0235 0.0982
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.0029 0.0235 0.3093
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0014 0.006 0.0615
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0014 0.006 0.016
Echinococcus granulosus solute carrier family 22 0.0029 0.0235 0.0628
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0046 0.0431 0.5402
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.001 0.0012 0.0045
Trypanosoma cruzi sugar transporter, putative 0.0029 0.0235 0.3093
Entamoeba histolytica hypothetical protein 0.0071 0.0721 1
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0205 0.228 0.61
Loa Loa (eye worm) hypothetical protein 0.0035 0.0306 0.1162
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0063 0.0629 0.1682
Loa Loa (eye worm) hypothetical protein 0.0029 0.0235 0.0891
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0056 0.0552 0.2094
Echinococcus multilocularis GPCR, family 2 0.0015 0.0077 0.0207
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0018 0.0112 0.1383
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0205 0.228 0.61
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0061 0.0614 0.2655
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0018 0.0112 0.0423
Loa Loa (eye worm) hypothetical protein 0.0029 0.0235 0.0891
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.0112 0.01
Treponema pallidum prolyl-tRNA synthetase 0.0022 0.0152 0.1808
Echinococcus multilocularis nibrin 0.001 0.0012 0.0032
Plasmodium vivax proline--tRNA ligase, putative 0.0072 0.0732 0.0721
Schistosoma mansoni protein kinase 0.0063 0.0629 0.2758
Trypanosoma cruzi Aminoacyl-tRNA editing domain containing protein, putative 0.001 0.0018 0.009
Schistosoma mansoni glucose transport protein 0.0205 0.228 1
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0235 0.0982
Schistosoma mansoni hypothetical protein 0.0205 0.228 1
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0018 0.0112 0.1383
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0026 0.0206 0.0194
Mycobacterium tuberculosis Probable conserved integral membrane transport protein 0.0029 0.0235 0.4057
Toxoplasma gondii ATPase, AAA family protein 0.001 0.0012 0.0018
Plasmodium vivax calcium-dependent protein kinase, putative 0.0063 0.0629 0.0618
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0063 0.0629 0.1682
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0235 0.0982
Schistosoma mansoni hypothetical protein 0.0015 0.0077 0.034
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0048 0.0458 0.1738
Loa Loa (eye worm) hypothetical protein 0.0029 0.0235 0.0891
Brugia malayi hypothetical protein 0.001 0.0012 0.0045
Schistosoma mansoni protein kinase 0.0063 0.0629 0.2758
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0063 0.0629 0.0618
Echinococcus granulosus nibrin 0.001 0.0012 0.0032
Trichomonas vaginalis glucose transporter, putative 0.0063 0.0638 0.2761
Trichomonas vaginalis conserved hypothetical protein 0.0063 0.0638 0.2761
Toxoplasma gondii YbaK/proline-tRNA ligase associated domain-containing protein 0.001 0.0018 0.0028
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0012 0.0037 0.0358
Entamoeba histolytica acyl-CoA synthetase, putative 0.0047 0.0444 0.609
Onchocerca volvulus 0.0029 0.0235 0.1216
Toxoplasma gondii lysine-tRNA ligase 0.0046 0.0431 0.0651
Toxoplasma gondii sugar transporter ST1 0.0029 0.0235 0.0354
Schistosoma mansoni ap endonuclease 0.0018 0.0112 0.0489
Brugia malayi hypothetical protein 0.001 0.0012 0.0045
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0063 0.0629 0.1682
Schistosoma mansoni hypothetical protein 0.0015 0.0077 0.034
Echinococcus granulosus solute carrier family 22 0.0029 0.0235 0.0628
Brugia malayi exodeoxyribonuclease III family protein 0.0018 0.0112 0.0423
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0014 0.006 0.0615
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0018 0.0112 0.0298
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0076 0.0788 1
Mycobacterium tuberculosis Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase)(ThrRS) (threonine-tRNA ligase) 0.0012 0.0034 0.0292
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.0284 0.4981
Toxoplasma gondii facilitative glucose transporter GT1 0.0205 0.228 0.3442
Schistosoma mansoni lysyl-tRNA synthetase 0.0046 0.0431 0.1892
Entamoeba histolytica hypothetical protein 0.0046 0.0431 0.5917
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0018 0.0112 0.1284
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0014 0.006 0.0226
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0063 0.0629 0.2387
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0014 0.006 0.0774
Mycobacterium leprae conserved hypothetical protein 0.001 0.0018 0.0084
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0026 0.0206 0.0194
Brugia malayi hypothetical protein 0.0235 0.2635 1
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0235 0.0982
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0046 0.0431 0.5402
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0014 0.006 0.009
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0235 0.0982
Schistosoma mansoni topbp1 0.001 0.0012 0.0052
Plasmodium falciparum mitogen-activated protein kinase 2 0.0331 0.3745 0.3738
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0035 0.0306 0.379
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.0112 0.0439
Plasmodium vivax sugar transporter, putative 0.0029 0.0235 0.0223
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0235 0.0982
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0056 0.0552 0.1476
Mycobacterium ulcerans acyl-CoA synthetase 0.0047 0.0444 0.556
Mycobacterium ulcerans integral membrane transport protein 0.0029 0.0235 0.287
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0018 0.0029
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.005 0.0482 0.8699
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0235 0.0982
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0235 0.0982
Trypanosoma brucei glucose transporter, putative 0.0063 0.0638 0.8692
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0063 0.0629 0.095
Onchocerca volvulus 0.0017 0.0104 0.0536
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0076 0.0788 1
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0026 0.0206 0.2501
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0235 0.0982
Trypanosoma brucei glucose transporter 2A 0.0063 0.0638 0.8692
Trichomonas vaginalis sugar transporter, putative 0.0063 0.0638 0.2761
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0015 0.0077 0.0294
Echinococcus granulosus Threonyl tRNA synthetase C 0.0012 0.0034 0.0091
Trichomonas vaginalis conserved hypothetical protein 0.0205 0.228 1
Leishmania major protein kinase, putative 0.0063 0.0629 0.855
Onchocerca volvulus 0.0014 0.006 0.0309
Trichomonas vaginalis CAMK family protein kinase 0.0063 0.0629 0.272
Loa Loa (eye worm) hypothetical protein 0.0033 0.0283 0.1075
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0205 0.228 0.61
Loa Loa (eye worm) hypothetical protein 0.0029 0.0235 0.0891
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0063 0.0629 0.1682
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0047 0.0444 0.556
Schistosoma mansoni protein kinase 0.0063 0.0629 0.2758
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0047 0.0444 0.556
Toxoplasma gondii sugar transporter ST2 0.0029 0.0235 0.0354
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0014 0.006 0.009
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0235 0.0982
Brugia malayi major facilitator superfamily protein 0.0029 0.0235 0.0891
Loa Loa (eye worm) major facilitator superfamily transporter 0.0029 0.0235 0.0891
Loa Loa (eye worm) hypothetical protein 0.0076 0.0788 0.2992
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0072 0.0732 1
Loa Loa (eye worm) hypothetical protein 0.0029 0.0235 0.0891
Mycobacterium ulcerans hypothetical protein 0.001 0.0018 0.0084
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0063 0.0629 0.8563
Mycobacterium ulcerans acyl-CoA synthetase 0.0014 0.006 0.0615
Trichomonas vaginalis antibiotic synthetase, putative 0.0014 0.006 0.0211
Chlamydia trachomatis threonine--tRNA ligase 0.0012 0.0034 0.0284
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0015 0.0077 0.0207
Trypanosoma cruzi Aminoacyl-tRNA editing domain containing protein, putative 0.001 0.0018 0.009
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0047 0.0444 0.556
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0018 0.0112 0.1305
Onchocerca volvulus 0.0029 0.0235 0.1216
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0063 0.0629 0.095
Trypanosoma brucei glucose transporter, putative 0.0063 0.0638 0.8692
Loa Loa (eye worm) bifunctional aminoacyl-tRNA synthetase 0.0025 0.0193 0.0733
Schistosoma mansoni lysyl-tRNA synthetase 0.0046 0.0431 0.1892
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0061 0.0614 0.8496
Schistosoma mansoni glucose transport protein 0.0205 0.228 1
Trypanosoma brucei THT1 - hexose transporter, putative 0.0063 0.0638 0.8692
Brugia malayi AMP-binding enzyme family protein 0.0014 0.006 0.0226
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0014 0.006 0.0774
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0056 0.0552 0.2419
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0047 0.0444 0.7973
Trypanosoma brucei Aminoacyl-tRNA editing domain containing protein, putative 0.001 0.0018 0.009
Brugia malayi glycyl-tRNA synthetase 0.0012 0.0034 0.0129
Loa Loa (eye worm) hypothetical protein 0.0029 0.0235 0.0891
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0056 0.0552 0.7468
Plasmodium falciparum hexose transporter 0.0205 0.228 0.2271
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0235 0.0982
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0071 0.0721 0.1928
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0205 0.228 0.61
Plasmodium falciparum protein kinase 7 0.0578 0.6623 0.6619
Brugia malayi AMP-binding enzyme family protein 0.0014 0.006 0.0226
Trichomonas vaginalis myo-inositol transporter, putative 0.0029 0.0235 0.0982
Loa Loa (eye worm) hypothetical protein 0.0047 0.0444 0.1683
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0014 0.006 0.0615
Schistosoma mansoni DNA ligase IV 0.001 0.0012 0.0052
Echinococcus granulosus geminin 0.0169 0.186 0.4976
Trypanosoma cruzi hypothetical protein, conserved 0.001 0.0018 0.009
Echinococcus multilocularis Threonyl tRNA synthetase, C 0.0012 0.0034 0.0091
Onchocerca volvulus 0.0048 0.0462 0.2393
Trichomonas vaginalis glucose transporter, putative 0.0029 0.0235 0.0982
Leishmania major myo-inositol/proton symporter (MIT) 0.0029 0.0235 0.303
Loa Loa (eye worm) hypothetical protein 0.001 0.0012 0.0045
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0235 0.0982
Mycobacterium ulcerans glycyl-tRNA synthetase 0.0012 0.0034 0.0284
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0063 0.0629 0.2387
Loa Loa (eye worm) hypothetical protein 0.015 0.1647 0.6253
Brugia malayi Major Facilitator Superfamily protein 0.0029 0.0235 0.0891
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.004 0.0366 0.156
Brugia malayi AMP-binding enzyme family protein 0.0014 0.006 0.0226
Loa Loa (eye worm) hypothetical protein 0.0014 0.006 0.0226
Echinococcus granulosus solute carrier family 22 0.0029 0.0235 0.0628
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0061 0.0614 0.1643
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0235 0.0982
Plasmodium vivax hexose transporter 0.0205 0.228 0.2271
Trypanosoma brucei sugar transporter, putative 0.0029 0.0235 0.3093
Giardia lamblia Threonyl-tRNA synthetase 0.0012 0.0034 0.0367
Plasmodium falciparum calcium-dependent protein kinase 3 0.0063 0.0629 0.0618
Schistosoma mansoni hypothetical protein 0.0169 0.186 0.8157
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0014 0.006 0.016
Schistosoma mansoni sugar transporter 0.0029 0.0235 0.1029
Brugia malayi hypothetical protein 0.0029 0.0235 0.0891
Plasmodium falciparum calcium-dependent protein kinase 5 0.0063 0.0629 0.0618
Loa Loa (eye worm) hypothetical protein 0.001 0.0012 0.0045
Onchocerca volvulus 0.0029 0.0235 0.1216
Trypanosoma brucei glucose transporter, putative 0.0063 0.0638 0.8692
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.0112 0.01
Schistosoma mansoni chromosome transmission fidelity factor 0.001 0.0012 0.0052
Brugia malayi lysyl-tRNA synthetase 0.0046 0.0431 0.1637
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.0284 0.4981
Echinococcus granulosus Sugar transporter ERD6 protein 0.0029 0.0235 0.0628
Loa Loa (eye worm) hypothetical protein 0.0029 0.0235 0.0891
Onchocerca volvulus 0.015 0.1647 0.8537
Mycobacterium ulcerans hypothetical protein 0.0047 0.0444 0.556
Schistosoma mansoni hypothetical protein 0.0071 0.0721 0.3161
Leishmania major glucose transporter, lmgt1 0.0063 0.0638 0.868
Leishmania major glucose transporter/membrane transporter D2, putative 0.0063 0.0638 0.868
Brugia malayi hypothetical protein 0.0029 0.0235 0.0891
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0235 0.0982
Onchocerca volvulus 0.0014 0.006 0.0309
Wolbachia endosymbiont of Brugia malayi prolyl-tRNA synthetase 0.0012 0.0034 0.0284
Trypanosoma cruzi hexose transporter 0.0063 0.0638 0.8692
Brugia malayi N-terminal motif family protein 0.0175 0.193 0.7325
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0235 0.0982
Loa Loa (eye worm) threonyl-tRNA synthetase 0.0012 0.0034 0.0129
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0076 0.0788 0.2109
Loa Loa (eye worm) hypothetical protein 0.0035 0.0306 0.1162
Schistosoma mansoni acetyl-CoA synthetase 0.0014 0.006 0.0262
Onchocerca volvulus 0.0048 0.0458 0.2372
Onchocerca volvulus 0.0029 0.0235 0.1216
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0076 0.0788 1
Loa Loa (eye worm) hypothetical protein 0.001 0.0012 0.0045
Entamoeba histolytica glycyl-tRNA synthetase, putative 0.0012 0.0034 0.0311
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0235 0.0982
Schistosoma mansoni cellular tumor antigen P53 0.0048 0.0462 0.2025
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0014 0.006 0.0774
Loa Loa (eye worm) hypothetical protein 0.005 0.048 0.1822
Echinococcus multilocularis peptidase Clp (S14 family) 0.005 0.0482 0.129
Brugia malayi Sugar transporter family protein 0.0029 0.0235 0.0891
Onchocerca volvulus 0.0029 0.0235 0.1216
Entamoeba histolytica protein kinase, putative 0.0063 0.0629 0.8704
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0035 0.0306 0.379
Loa Loa (eye worm) hypothetical protein 0.0014 0.006 0.0226
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0076 0.0788 1
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.0029 0.0235 0.287
Schistosoma mansoni glucose transport protein 0.0205 0.228 1
Loa Loa (eye worm) hypothetical protein 0.0015 0.0077 0.0294
Wolbachia endosymbiont of Brugia malayi threonyl-tRNA synthetase 0.0012 0.0034 0.0284
Onchocerca volvulus 0.0029 0.0235 0.1216
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0014 0.006 0.0774
Trichomonas vaginalis sugar transporter, putative 0.0063 0.0638 0.2761
Leishmania major 4-coumarate:coa ligase-like protein 0.0047 0.0444 0.5955
Brugia malayi threonyl-tRNA synthetase, cytoplasmic 0.0012 0.0034 0.0129
Trypanosoma cruzi glucose transporter, putative 0.0029 0.0235 0.3093
Brugia malayi DKFZp564C0469 protein 0.001 0.0012 0.0045
Onchocerca volvulus 0.0029 0.0235 0.1216
Mycobacterium leprae Probable lysyl-tRNA synthase LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0039 0.0351 0.4371
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0235 0.0982
Mycobacterium ulcerans acyl-CoA synthetase 0.0014 0.006 0.0615
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0235 0.0982
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0235 0.0982
Loa Loa (eye worm) hypothetical protein 0.0048 0.0462 0.1753
Echinococcus multilocularis synaptic vesicle 2 protein 0.0029 0.0235 0.0628
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0072 0.0732 1
Onchocerca volvulus 0.0029 0.0235 0.1216
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0056 0.0552 1
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0063 0.0629 0.0618
Onchocerca volvulus 0.0029 0.0235 0.1216
Mycobacterium leprae Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase) (ThrRS) (Threonine-tRNA ligase) 0.0012 0.0034 0.0284
Onchocerca volvulus 0.001 0.0012 0.0062
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0046 0.0431 0.1849
Mycobacterium ulcerans acyl-CoA synthetase 0.0047 0.0444 0.556
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0014 0.006 0.0615
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0047 0.0444 0.556
Mycobacterium ulcerans threonyl-tRNA synthetase 0.0012 0.0034 0.0284
Treponema pallidum exodeoxyribonuclease (exoA) 0.0018 0.0112 0.1284
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0235 0.0982
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.005 0.0482 0.8699
Entamoeba histolytica protein kinase, putative 0.0063 0.0629 0.8704
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0014 0.006 0.0578
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0205 0.228 0.61
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0072 0.0732 0.1106
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0014 0.006 0.0774
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0063 0.0629 0.1682
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0061 0.0614 0.2693
Trypanosoma cruzi hypothetical protein, conserved 0.001 0.0018 0.009
Echinococcus multilocularis glycyl tRNA synthetase 0.0012 0.0034 0.0091
Echinococcus granulosus synaptic vesicle 2 protein 0.0029 0.0235 0.0628
Loa Loa (eye worm) hypothetical protein 0.0029 0.0235 0.0891
Brugia malayi AMP-binding enzyme family protein 0.0047 0.0444 0.1683
Schistosoma mansoni hypothetical protein 0.0169 0.186 0.8157
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.0029 0.0235 0.287
Giardia lamblia Sugar-proton symporter 0.0029 0.0235 0.37
Toxoplasma gondii protein kinase, putative 0.0578 0.6623 1
Echinococcus granulosus tumor protein p63 0.033 0.3737 1
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0076 0.0788 0.119
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0076 0.0788 1
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0076 0.0788 1
Toxoplasma gondii propionate-CoA ligase 0.0014 0.006 0.009
Brugia malayi Major Facilitator Superfamily protein 0.0029 0.0235 0.0891
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0046 0.0431 0.5402
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0014 0.006 0.0615
Schistosoma mansoni hypothetical protein 0.0015 0.0077 0.034
Schistosoma mansoni transcription factor LCR-F1 0.0071 0.0721 0.3161
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0056 0.0552 0.1476
Brugia malayi latrophilin 2 splice variant baaae 0.0033 0.0283 0.1075
Trichomonas vaginalis glucose transporter, putative 0.0063 0.0638 0.2761
Plasmodium vivax glycine--tRNA ligase, putative 0.0012 0.0034 0.0022
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0046 0.0431 0.5821
Treponema pallidum threonyl-tRNA synthetase 0.0012 0.0034 0.0284
Trypanosoma cruzi hexose transporter, putative 0.0063 0.0638 0.8692
Trypanosoma cruzi threonyl-tRNA synthetase, putative 0.0012 0.0034 0.0306
Loa Loa (eye worm) hypothetical protein 0.0035 0.0306 0.1162
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0047 0.0444 0.556
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0071 0.0721 0.1928
Loa Loa (eye worm) hypothetical protein 0.001 0.0012 0.0045
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0014 0.006 0.0774
Plasmodium vivax threonine--tRNA ligase, putative 0.0012 0.0034 0.0022
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0014 0.006 0.0615
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0056 0.0552 0.6952
Mycobacterium ulcerans acyl-CoA synthetase 0.0014 0.006 0.0615
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0029 0.0235 0.0628
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0056 0.0552 0.6952
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0076 0.0788 0.2109
Leishmania major glucose transporter, lmgt3 0.0063 0.0638 0.868
Echinococcus granulosus solute carrier family 22 0.0029 0.0235 0.0628
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0235 0.0982
Onchocerca volvulus 0.0029 0.0235 0.1216
Loa Loa (eye worm) hypothetical protein 0.0029 0.0235 0.0891
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0047 0.0444 0.7973
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.0284 0.4981
Mycobacterium ulcerans acyl-CoA synthetase 0.0014 0.006 0.0615
Loa Loa (eye worm) hypothetical protein 0.0029 0.0235 0.0891
Toxoplasma gondii threonyl-tRNA synthetase family protein 0.0012 0.0034 0.0051
Echinococcus multilocularis tumor protein p63 0.033 0.3737 1
Schistosoma mansoni peptidase Clp (S14 family) 0.0076 0.0788 0.3457
Trypanosoma cruzi threonyl-tRNA synthetase, putative 0.0012 0.0034 0.0306
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0235 0.0982
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0235 0.0982
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0063 0.0629 0.2387
Trypanosoma brucei THT1 - hexose transporter, putative 0.0063 0.0638 0.8692
Mycobacterium ulcerans prolyl-tRNA synthetase 0.0022 0.0152 0.1808
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0014 0.006 0.0663
Mycobacterium ulcerans sugar transporter 0.0029 0.0235 0.287
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0014 0.006 0.0226
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0063 0.0629 0.1682
Plasmodium falciparum proline--tRNA ligase 0.0072 0.0732 0.0721
Echinococcus multilocularis General substrate transporter 0.0176 0.1945 0.5205
Giardia lamblia Prolyl-tRNA synthetase 0.0061 0.0614 1
Mycobacterium ulcerans acyl-CoA synthetase 0.0014 0.006 0.0615
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0235 0.0982
Schistosoma mansoni hypothetical protein 0.0033 0.0283 0.1242
Echinococcus granulosus General substrate transporter 0.0176 0.1945 0.5205
Plasmodium falciparum calcium-dependent protein kinase 2 0.0063 0.0629 0.0618
Schistosoma mansoni sugar transporter 0.0029 0.0235 0.1029
Leishmania major hypothetical protein, conserved 0.0029 0.0235 0.303
Entamoeba histolytica hypothetical protein 0.0071 0.0721 1
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0205 0.228 0.61

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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