Detailed information for compound 804883

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 445.254 | Formula: C19H16IN3O2
  • H donors: 2 H acceptors: 3 LogP: 4.12 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCOc1cc(cc(c1O)I)C=C(c1[nH]c2c(n1)cc(cc2)C)C#N
  • InChi: 1S/C19H16IN3O2/c1-3-25-17-9-12(8-14(20)18(17)24)7-13(10-21)19-22-15-5-4-11(2)6-16(15)23-19/h4-9,24H,3H2,1-2H3,(H,22,23)/b13-7+
  • InChiKey: BXDHYFNWZOMSPI-NTUHNPAUSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis lamin 0.0026 0.0227 0.1138
Onchocerca volvulus 0.0015 0.0096 0.0674
Brugia malayi nuclear hormone receptor 0.0007 0.0001 0.0004
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0015 0.0096 0.0095
Trypanosoma cruzi calcium motive p-type ATPase, putative 0.0013 0.0069 0.0392
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0016 0.0109 0.048
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0062 0.065 0.3272
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0015 0.0096 0.0677
Onchocerca volvulus Huntingtin homolog 0.0126 0.1412 1
Schistosoma mansoni calcium-transporting atpase sarcoplasmic/endoplasmic reticulum type (calcium pump) 0.0013 0.0069 0.0069
Schistosoma mansoni thyroid hormone receptor 0.0015 0.0096 0.0095
Brugia malayi Nuclear hormone receptor-like 1 0.0008 0.0011 0.0076
Treponema pallidum glucose-6-phosphate 1-dehydrogenase 0.0121 0.1349 0.5
Schistosoma mansoni steroid hormone receptor ad4bp 0.0015 0.0096 0.0095
Loa Loa (eye worm) hypothetical protein 0.0015 0.0096 0.0674
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.0227 0.1601
Echinococcus multilocularis nervana 2 0.0062 0.065 0.3272
Brugia malayi nuclear receptor RXR 0.0008 0.0011 0.0076
Schistosoma mansoni glucose-6-phosphate 1-dehydrogenase 0.0121 0.1349 0.1349
Schistosoma mansoni calcium-transporting atpase 2 (atpase 2) 0.0012 0.0059 0.0059
Echinococcus multilocularis calcium transporting ATPase type 2C member 0.0012 0.0059 0.0295
Schistosoma mansoni hypothetical protein 0.0174 0.1986 0.1985
Brugia malayi Sodium/potassium-transporting ATPase alpha chain, putative 0.0008 0.0007 0.0049
Schistosoma mansoni thyroid hormone receptor 0.0015 0.0096 0.0095
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0062 0.065 0.3272
Loa Loa (eye worm) hypothetical protein 0.001 0.0036 0.0251
Brugia malayi Membrane calcium atpase protein 3 0.0017 0.0119 0.0841
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0015 0.0095 1
Toxoplasma gondii calcium-translocating P-type ATPase, PMCA-type protein 0.0016 0.0105 0.0359
Brugia malayi Nuclear hormone receptor-like 1 0.0015 0.0096 0.0677
Echinococcus granulosus nervana 2 0.0062 0.065 0.3272
Brugia malayi steroid hormone receptor 0.0015 0.0096 0.0677
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0015 0.0096 0.0677
Onchocerca volvulus 0.0062 0.065 0.4601
Loa Loa (eye worm) hypothetical protein 0.0012 0.006 0.0421
Toxoplasma gondii plasma membrane-type Ca(2+)-ATPase A1 PMCAA1 0.0017 0.0119 0.0462
Leishmania major glucose-6-phosphate 1-dehydrogenase, putative 0.0121 0.1349 1
Echinococcus granulosus lamin dm0 0.0026 0.0227 0.1138
Schistosoma mansoni calcium-transporting atpase sarcoplasmic/endoplasmic reticulum type (calcium pump) 0.0013 0.0069 0.0069
Trichomonas vaginalis cation-transporting ATPase fungi, putative 0.0015 0.0095 0.0379
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0015 0.0096 0.0479
Loa Loa (eye worm) hypothetical protein 0.0008 0.0011 0.0072
Giardia lamblia Plasma membrane calcium-transporting ATPase 2 0.0015 0.0095 0.0379
Schistosoma mansoni plasma membrane calcium-transporting atpase 0.0017 0.0119 0.0118
Echinococcus granulosus Ca2 transporting ATPase plasma membrane 0.0017 0.0119 0.0595
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0016 0.0109 0.048
Brugia malayi hypothetical protein 0.0007 0.0001 0.0004
Loa Loa (eye worm) hypothetical protein 0.0015 0.0096 0.0674
Entamoeba histolytica calcium-transporting P-type ATPase, putative 0.0012 0.0059 0.4923
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0015 0.0095 0.0379
Onchocerca volvulus 0.0026 0.0227 0.1601
Brugia malayi Steroid receptor seven-up type 2 0.0015 0.0096 0.0677
Brugia malayi ecdysteroid receptor 0.0015 0.0096 0.0677
Schistosoma mansoni na+/k+ atpase alpha subunit 0.0012 0.0059 0.0059
Brugia malayi hypothetical protein 0.0008 0.0011 0.0076
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0014 0.0082 0.0578
Brugia malayi nuclear receptor NHR-88 0.0015 0.0096 0.0677
Echinococcus multilocularis glucose 6 phosphate 1 dehydrogenase 0.0121 0.1349 0.6793
Schistosoma mansoni ATP synthase F0 subunit 6 0.0223 0.2568 0.2568
Trypanosoma cruzi glucose-6-phosphate 1-dehydrogenase, putative 0.0121 0.1349 1
Mycobacterium ulcerans glucose-6-phosphate 1-dehydrogenase 0.0079 0.0852 0.3196
Echinococcus granulosus nervana 2 0.0062 0.065 0.3272
Loa Loa (eye worm) hypothetical protein 0.0062 0.065 0.4601
Toxoplasma gondii glucose-6-phosphate 1-dehydrogenase 0.0079 0.0852 0.6145
Wolbachia endosymbiont of Brugia malayi ATP synthase F0F1 subunit A 0.0223 0.2568 0.5
Echinococcus granulosus plasma membrane calcium transporting ATPase 0.0017 0.0119 0.0595
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0008 0.0011 0.0072
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0015 0.0096 0.0674
Brugia malayi ecdysone receptor 0.0007 0.0001 0.0004
Brugia malayi orphan nuclear receptor NR2E1 0.0007 0.0001 0.0004
Schistosoma mansoni hypothetical protein 0.0174 0.1986 0.1985
Onchocerca volvulus Bile acid receptor homolog 0.0015 0.0096 0.0674
Plasmodium vivax glucose-6-phosphate 1-dehydrogenase, putative 0.0121 0.1349 1
Echinococcus granulosus FTZ F1 alpha 0.0015 0.0096 0.0479
Brugia malayi Nuclear hormone receptor E75 0.0007 0.0001 0.0004
Echinococcus multilocularis geminin 0.0174 0.1986 1
Mycobacterium leprae PROBABLE ATP SYNTHASE A CHAIN ATPB (PROTEIN 6) 0.0223 0.2568 0.5
Echinococcus granulosus lamin 0.0026 0.0227 0.1138
Mycobacterium tuberculosis Probable ATP synthase a chain AtpB (protein 6) 0.0223 0.2568 1
Loa Loa (eye worm) hypothetical protein 0.0012 0.0059 0.0415
Leishmania major vacuolar-type Ca2 -ATPase, putative 0.0015 0.0095 0.0379
Loa Loa (eye worm) hypothetical protein 0.0015 0.0096 0.0674
Echinococcus multilocularis thyroid hormone receptor alpha 0.0015 0.0096 0.0479
Echinococcus granulosus sarco:endoplasmic reticulum calcium ATPase 0.0011 0.0046 0.0228
Brugia malayi nuclear receptor NHR-67 0.0007 0.0001 0.0004
Loa Loa (eye worm) hypothetical protein 0.0013 0.0066 0.0461
Brugia malayi nuclear receptor RXR 0.0007 0.0001 0.0004
Schistosoma mansoni Na+/K+ transporting ATPase subunit alpha 0.0012 0.0059 0.0059
Loa Loa (eye worm) hypothetical protein 0.0008 0.0011 0.0072
Giardia lamblia Glucose-6-phosphate 1-dehydrogenase 0.0121 0.1349 1
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0015 0.0096 0.0479
Loa Loa (eye worm) hypothetical protein 0.0008 0.0011 0.0072
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0015 0.0096 0.0677
Echinococcus multilocularis Tetracycline resistance leader peptide, TetL 0.0016 0.0109 0.0543
Brugia malayi conserved hypotetical protein 0.0007 0.0001 0.0004
Echinococcus multilocularis plasma membrane calcium transporting ATPase 0.0017 0.0119 0.0595
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0062 0.065 0.3272
Schistosoma mansoni sodium/potassium-dependent atpase beta subunit 0.0062 0.065 0.065
Onchocerca volvulus 0.0026 0.0227 0.1601
Echinococcus multilocularis sarco:endoplasmic reticulum calcium ATPase 0.0011 0.0046 0.0228
Trichomonas vaginalis 6-phosphogluconolactonase, putative 0.0121 0.1349 1
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0015 0.0096 0.0677
Schistosoma mansoni transmemberane protein 0.0062 0.065 0.065
Schistosoma mansoni intermediate filament proteins 0.0026 0.0227 0.0226
Trypanosoma brucei vacuolar-type Ca2+-ATPase 2 0.0015 0.0095 0.0586
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0062 0.065 0.3272
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0015 0.0096 0.0677
Onchocerca volvulus 0.0011 0.0046 0.0321
Trichomonas vaginalis glucosamine-6-phosphate isomerase, putative 0.0121 0.1349 1
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0015 0.0096 0.0479
Schistosoma mansoni lamin 0.0026 0.0227 0.0226
Trypanosoma cruzi Glucose-6-phosphate dehydrogenase, putative 0.0039 0.0377 0.2701
Echinococcus multilocularis nervana 2 0.0062 0.065 0.3272
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0008 0.0011 0.001
Mycobacterium ulcerans F0F1 ATP synthase subunit A 0.0223 0.2568 1
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0008 0.0011 0.0051
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0015 0.0096 0.0677
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0015 0.0095 1
Schistosoma mansoni hypothetical protein 0.0103 0.1144 0.1143
Entamoeba histolytica plasma membrane calcium ion-transporting ATPase, putative 0.001 0.0037 0.1869
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0007 0.0001 0.0004
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0015 0.0096 0.0479
Trypanosoma cruzi calcium motive p-type ATPase, putative 0.0013 0.0069 0.0392
Loa Loa (eye worm) calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type 0.0009 0.0017 0.0118
Chlamydia trachomatis glucose-6-phosphate 1-dehydrogenase 0.0121 0.1349 0.5
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0015 0.0096 0.0095
Schistosoma mansoni nuclear hormone receptor 0.0015 0.0096 0.0095
Schistosoma mansoni ATPase 0.0011 0.0046 0.0045
Echinococcus granulosus intermediate filament protein 0.0026 0.0227 0.1138
Brugia malayi nuclear hormone receptor family member odr-7 0.0007 0.0001 0.0004
Echinococcus multilocularis FTZ F1 alpha 0.0015 0.0096 0.0479
Trypanosoma cruzi plasma membrane Ca2+ ATPase 0.0015 0.0095 0.0586
Trypanosoma cruzi plasma membrane Ca2+ ATPase 0.0015 0.0095 0.0586
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0015 0.0096 0.0674
Echinococcus multilocularis nervana 2 0.0062 0.065 0.3272
Loa Loa (eye worm) hypothetical protein 0.0015 0.0096 0.0674
Mycobacterium ulcerans metal cation-transporting p-type ATPase F, CtpF 0.0012 0.0059 0.0053
Echinococcus granulosus glucose 6 phosphate 1 dehydrogenase 0.0121 0.1349 0.6793
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0015 0.0096 0.0479
Onchocerca volvulus 0.0062 0.065 0.4601
Brugia malayi nuclear hormone receptor family member nhr-6 0.0007 0.0001 0.0004
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0015 0.0096 0.0479
Brugia malayi intermediate filament protein 0.0026 0.0227 0.1604
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0015 0.0096 0.0677
Brugia malayi calcium ATPase 0.0011 0.0048 0.0338
Leishmania major P-type ATPase, putative 0.0017 0.0119 0.0559
Trypanosoma cruzi Calcium ATPase SERCA-like 0.0011 0.0046 0.0215
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0013 0.0066 0.0328
Echinococcus granulosus nervana 2 0.0062 0.065 0.3272
Giardia lamblia Potassium-transporting ATPase alpha chain 1 0.0012 0.0059 0.0102
Loa Loa (eye worm) hypothetical protein 0.0008 0.0011 0.0072
Loa Loa (eye worm) hypothetical protein 0.0015 0.0096 0.0674
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0015 0.0096 0.0479
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0015 0.0096 0.0095
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0015 0.0096 0.0479
Echinococcus multilocularis lamin dm0 0.0026 0.0227 0.1138
Brugia malayi Calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type 0.0013 0.0069 0.0491
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0015 0.0096 0.0095
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0015 0.0095 0.0379
Schistosoma mansoni sodium/potassium-dependent atpase beta subunit 0.0062 0.065 0.065
Loa Loa (eye worm) steroid hormone receptor 0.0015 0.0096 0.0674
Brugia malayi nuclear hormone receptor 0.0015 0.0096 0.0677
Trypanosoma brucei vacuolar-type Ca2+-ATPase 1 0.0015 0.0095 0.0586
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0015 0.0096 0.0674
Trypanosoma brucei calcium-translocating P-type ATPase 0.0013 0.0069 0.0392
Onchocerca volvulus Huntingtin homolog 0.0126 0.1412 1
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0015 0.0096 0.0674
Brugia malayi Nuclear hormone receptor-like 1 0.0008 0.0011 0.0076
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0015 0.0096 0.0677
Leishmania major calcium-transporting ATPase, putative 0.0013 0.0069 0.018
Trichomonas vaginalis cation-transporting ATPase, putative 0.0015 0.0095 0.0379
Loa Loa (eye worm) hypothetical protein 0.0126 0.1412 1
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0015 0.0096 0.0095
Echinococcus granulosus ecdysone induced protein 78C 0.0015 0.0096 0.0479
Echinococcus granulosus sodium:potassium transporting ATPase subunit 0.0062 0.065 0.3272
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0015 0.0096 0.0674
Schistosoma mansoni retinoic acid receptor RXR 0.0015 0.0096 0.0095
Loa Loa (eye worm) hypothetical protein 0.0013 0.0067 0.0467
Brugia malayi hypothetical protein 0.0126 0.1412 1
Trypanosoma cruzi glucose-6-phosphate 1-dehydrogenase, putative 0.004 0.0391 0.2804
Brugia malayi nuclear receptor NHR-88 0.0007 0.0001 0.0004
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0015 0.0096 0.0674
Plasmodium falciparum glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase 0.0121 0.1349 1
Loa Loa (eye worm) hypothetical protein 0.0126 0.1412 1
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0015 0.0096 0.0674
Trypanosoma brucei glucose-6-phosphate 1-dehydrogenase 0.0121 0.1349 1
Onchocerca volvulus Protein ultraspiracle homolog 0.0015 0.0096 0.0674
Brugia malayi hypothetical protein 0.0007 0.0001 0.0004
Loa Loa (eye worm) Na,K-ATPase alpha subunit 0.0012 0.0059 0.0415
Leishmania major vacuolar-type Ca2 -ATPase, putative 0.0015 0.0095 0.0379
Brugia malayi cytoplasmic intermediate filament protein 0.0014 0.0082 0.0582
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0062 0.065 0.3272
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0015 0.0096 0.0677
Echinococcus multilocularis calcium transporting atpase 0.0013 0.0069 0.0346
Echinococcus multilocularis sodium:potassium transporting ATPase subunit 0.0062 0.065 0.3272
Schistosoma mansoni RAR-like nuclear receptor 0.0015 0.0096 0.0095
Echinococcus multilocularis Ca2+ transporting ATPase plasma membrane 0.0017 0.0119 0.0595
Echinococcus granulosus plasma membrane calcium transporting ATPase 2 0.0016 0.0109 0.0543
Brugia malayi tailless protein 0.0007 0.0001 0.0004
Trypanosoma brucei calcium motive p-type ATPase, putative 0.0013 0.0069 0.0392
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0015 0.0095 1
Schistosoma mansoni lamin 0.0026 0.0227 0.0226
Loa Loa (eye worm) hypothetical protein 0.0015 0.0096 0.0674
Loa Loa (eye worm) hypothetical protein 0.0011 0.0046 0.0321
Echinococcus granulosus calcium transporting ATPase type 2C member 0.0012 0.0059 0.0295
Trypanosoma brucei vacuolar-type Ca2+-ATPase, putative 0.0015 0.0095 0.0586
Loa Loa (eye worm) hypothetical protein 0.0015 0.0096 0.0674
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0015 0.0096 0.0677
Entamoeba histolytica plasma membrane calcium ion-transporting ATPase, putative 0.0011 0.0049 0.3541
Loa Loa (eye worm) hypothetical protein 0.0012 0.006 0.0421
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0013 0.0066 0.0328
Echinococcus multilocularis nervana 2 0.0062 0.065 0.3272
Schistosoma mansoni ATPase 0.0011 0.0046 0.0045
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0015 0.0096 0.0479
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0015 0.0096 0.0095
Leishmania major calcium motive p-type ATPase, putative 0.0013 0.0069 0.018
Toxoplasma gondii glucose-6-phosphate 1-dehydrogenase 0.0121 0.1349 1
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0015 0.0096 0.0479
Brugia malayi photoreceptor-specific nuclear receptor 0.0015 0.0096 0.0677
Echinococcus multilocularis Na+:K+ ATPase alpha subunit 0.0012 0.0059 0.0295
Brugia malayi hypothetical protein 0.0008 0.0011 0.0076
Echinococcus granulosus geminin 0.0174 0.1986 1
Trichomonas vaginalis glucosamine-6-phosphate isomerase, putative 0.0121 0.1349 1
Brugia malayi glucose-6-phosphate dehydrogenase 0.0121 0.1349 0.9552
Echinococcus granulosus nervana 2 0.0062 0.065 0.3272
Loa Loa (eye worm) hypothetical protein 0.0015 0.0096 0.0674
Brugia malayi Nuclear hormone receptor E75 0.0007 0.0001 0.0004
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0015 0.0096 0.0677
Schistosoma mansoni sodium / potassium ATPase beta chain 0.0849 1 1
Loa Loa (eye worm) calcium ATPase 0.001 0.0037 0.0261
Loa Loa (eye worm) glucose-6-phosphate dehydrogenase 0.0121 0.1349 0.9552
Loa Loa (eye worm) hypothetical protein 0.0008 0.0011 0.0072
Loa Loa (eye worm) intermediate filament protein 0.0026 0.0227 0.1601
Mycobacterium ulcerans glucose-6-phosphate 1-dehydrogenase 0.0121 0.1349 0.5167
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0062 0.065 0.3272
Echinococcus multilocularis musashi 0.0026 0.0227 0.1138
Echinococcus granulosus Na:K ATPase alpha subunit 0.0012 0.0059 0.0295
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0015 0.0096 0.0479
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0015 0.0095 0.0379
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0015 0.0096 0.0677
Schistosoma mansoni coup transcription factor 0.0015 0.0096 0.0095
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0015 0.0096 0.0479
Loa Loa (eye worm) hypothetical protein 0.0026 0.0227 0.1601
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0008 0.0011 0.0051
Brugia malayi Intermediate filament tail domain containing protein 0.0026 0.0227 0.1604
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0008 0.0011 0.001
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0015 0.0095 0.0379
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0015 0.0096 0.0677
Brugia malayi Na,K-ATPase alpha subunit 0.0012 0.0059 0.0419
Loa Loa (eye worm) sodium/potassium-transporting ATPase subunit alpha 0.0008 0.0007 0.0045
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0015 0.0096 0.0479
Loa Loa (eye worm) hypothetical protein 0.0062 0.065 0.4601
Loa Loa (eye worm) hypothetical protein 0.0026 0.0221 0.1561
Echinococcus granulosus calcium transporting atpase 0.0013 0.0069 0.0346
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0015 0.0096 0.0674
Brugia malayi Probable calcium-transporting ATPase KIAA0703 0.0008 0.0007 0.0049
Echinococcus multilocularis ecdysone induced protein 78C 0.0015 0.0096 0.0479
Schistosoma mansoni plasma membrane calcium-transporting atpase 0.0017 0.0119 0.0118

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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