Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | tyrosine kinase | 0.0174 | 0.1706 | 0.2239 |
Mycobacterium tuberculosis | Probable sensor protein KdpD | 0.0018 | 0.0052 | 0.0068 |
Brugia malayi | hypothetical protein | 0.0165 | 0.1608 | 0.2115 |
Loa Loa (eye worm) | hypothetical protein | 0.0105 | 0.0979 | 0.0975 |
Chlamydia trachomatis | two component regulatory system sensor histidine kinase | 0.0018 | 0.0052 | 0.5 |
Trypanosoma brucei | fructose-1,6-bisphosphatase | 0.0726 | 0.7587 | 1 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0042 | 0.0299 | 0.0382 |
Trichomonas vaginalis | sensory transduction histidine kinase bacterial, putative | 0.0024 | 0.0109 | 0.0346 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0472 | 0.4884 | 0.4881 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0033 | 0.0209 | 0.0263 |
Loa Loa (eye worm) | fructose-1,6-bisphosphatase | 0.0726 | 0.7587 | 0.7586 |
Schistosoma mansoni | smad1 5 8 and | 0.0032 | 0.0199 | 0.025 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0472 | 0.4884 | 0.4881 |
Echinococcus granulosus | epidermal growth factor receptor | 0.0093 | 0.085 | 0.111 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0145 | 0.1401 | 0.1487 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0113 | 0.1062 | 0.1389 |
Loa Loa (eye worm) | hepatopoietin HPO2 | 0.0038 | 0.0264 | 0.026 |
Onchocerca volvulus | 0.0113 | 0.1062 | 0.4069 | |
Mycobacterium ulcerans | glutaminase | 0.0298 | 0.3026 | 1 |
Trypanosoma cruzi | fructose-1,6-bisphosphatase, cytosolic, putative | 0.0726 | 0.7587 | 1 |
Echinococcus granulosus | fructose 16 bisphosphatase 1 | 0.0726 | 0.7587 | 1 |
Mycobacterium tuberculosis | Conserved protein | 0.0113 | 0.1062 | 0.1405 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0113 | 0.1062 | 0.1405 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.0168 | 0.1648 | 0.2162 |
Trypanosoma brucei | ERV/ALR sulfhydryl oxidase domain-containing protein | 0.0038 | 0.0264 | 0.0342 |
Mycobacterium leprae | Probable lipase LipE | 0.0113 | 0.1062 | 1 |
Trichomonas vaginalis | glutaminase, putative | 0.0298 | 0.3026 | 1 |
Trichomonas vaginalis | sensory transduction histidine kinase, putative | 0.0024 | 0.0109 | 0.0346 |
Brugia malayi | Pre-SET motif family protein | 0.0227 | 0.2271 | 0.2989 |
Trypanosoma cruzi | Present in the outer mitochondrial membrane proteome 4 | 0.0038 | 0.0264 | 0.0342 |
Brugia malayi | MH1 domain containing protein | 0.0032 | 0.0199 | 0.0256 |
Echinococcus granulosus | cpg binding protein | 0.0031 | 0.0187 | 0.0234 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0376 | 0.0372 |
Schistosoma mansoni | smad1 5 8 and | 0.0032 | 0.0199 | 0.025 |
Schistosoma mansoni | alpha-glucosidase | 0.0145 | 0.1398 | 0.1833 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0724 | 0.756 | 1 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0042 | 0.0299 | 0.0295 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0042 | 0.0299 | 0.0389 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0037 | 0.0254 | 0.0826 |
Echinococcus granulosus | insulin growth factor 1 receptor beta | 0.0056 | 0.0448 | 0.0578 |
Brugia malayi | Furin-like cysteine rich region family protein | 0.0174 | 0.1706 | 0.2244 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.006 | 0.0498 | 0.0393 |
Leishmania major | hypothetical protein, conserved | 0.0113 | 0.1062 | 0.1395 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0029 | 0.0169 | 0.0165 |
Schistosoma mansoni | Smad4 | 0.0032 | 0.0199 | 0.025 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0042 | 0.0299 | 0.031 |
Schistosoma mansoni | cpg binding protein | 0.0031 | 0.0187 | 0.0234 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.001 | 0.0005 |
Schistosoma mansoni | hypothetical protein | 0.0369 | 0.3781 | 0.4978 |
Mycobacterium tuberculosis | Two component sensor histidine kinase PrrB | 0.0018 | 0.0052 | 0.0068 |
Schistosoma mansoni | lamin | 0.0055 | 0.0437 | 0.0564 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0076 | 0.0666 | 0.5364 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0113 | 0.1062 | 0.1125 |
Toxoplasma gondii | Erv1 / Alr family protein | 0.0038 | 0.0264 | 0.0075 |
Brugia malayi | beta-lactamase family protein | 0.0113 | 0.1062 | 0.1395 |
Echinococcus multilocularis | GPCR, family 2 | 0.0049 | 0.0376 | 0.0392 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0014 | 0.001 | 0.0005 |
Schistosoma mansoni | hypothetical protein | 0.0049 | 0.0376 | 0.0484 |
Mycobacterium tuberculosis | Two component sensory transduction histidine kinase MtrB | 0.0018 | 0.0052 | 0.0068 |
Toxoplasma gondii | fructose-bisphospatase II | 0.0726 | 0.7587 | 1 |
Trypanosoma cruzi | fructose-1,6-bisphosphatase, cytosolic, putative | 0.0726 | 0.7587 | 1 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0037 | 0.0254 | 0.0826 |
Mycobacterium tuberculosis | Conserved protein | 0.0113 | 0.1062 | 0.1405 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0037 | 0.0254 | 0.0329 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0113 | 0.1062 | 0.1389 |
Schistosoma mansoni | smad | 0.0032 | 0.0199 | 0.025 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.0526 | 0.0682 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0037 | 0.0254 | 0.0329 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0055 | 0.0437 | 0.057 |
Schistosoma mansoni | fructose-16-bisphosphatase-related | 0.0726 | 0.7587 | 1 |
Echinococcus multilocularis | neutral alpha glucosidase AB | 0.0037 | 0.0254 | 0.0261 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0113 | 0.1062 | 0.1395 |
Brugia malayi | beta-lactamase | 0.0113 | 0.1062 | 0.1395 |
Leishmania major | hypothetical protein, conserved | 0.0038 | 0.0264 | 0.0342 |
Trichomonas vaginalis | sensor histidine kinase, putative | 0.0024 | 0.0109 | 0.0346 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0046 | 0.0041 |
Schistosoma mansoni | hypothetical protein | 0.0369 | 0.3781 | 0.4978 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0227 | 0.2271 | 0.2267 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0035 | 0.0229 | 0.029 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0037 | 0.0254 | 0.0826 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0076 | 0.0666 | 0.0621 |
Echinococcus granulosus | tumor protein p63 | 0.0328 | 0.3352 | 0.4411 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.006 | 0.0498 | 0.0659 |
Loa Loa (eye worm) | glutaminase 2 | 0.0298 | 0.3026 | 0.3023 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0145 | 0.1401 | 0.1397 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0042 | 0.0299 | 0.1063 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.006 | 0.0498 | 0.0523 |
Trypanosoma brucei | glucosidase, putative | 0.0037 | 0.0254 | 0.0329 |
Loa Loa (eye worm) | hypothetical protein | 0.0113 | 0.1062 | 0.1058 |
Onchocerca volvulus | 0.0113 | 0.1062 | 0.4069 | |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0049 | 0.0376 | 0.0484 |
Loa Loa (eye worm) | hypothetical protein | 0.0113 | 0.1062 | 0.1058 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0033 | 0.0209 | 0.0263 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0145 | 0.1401 | 0.1487 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0113 | 0.1062 | 0.1405 |
Schistosoma mansoni | tyrosine kinase | 0.0092 | 0.084 | 0.1096 |
Loa Loa (eye worm) | TK/EGFR protein kinase | 0.0174 | 0.1706 | 0.1702 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0042 | 0.0299 | 0.0875 |
Echinococcus multilocularis | lamin dm0 | 0.0055 | 0.0437 | 0.0457 |
Echinococcus multilocularis | atpase aaa+ type core atpase aaa type core | 0.0893 | 0.9364 | 1 |
Schistosoma mansoni | lamin | 0.0055 | 0.0437 | 0.0564 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0126 | 0.0122 |
Echinococcus granulosus | lamin | 0.0055 | 0.0437 | 0.0564 |
Mycobacterium ulcerans | hypothetical protein | 0.0113 | 0.1062 | 0.3398 |
Echinococcus granulosus | mothers against decapentaplegic 5 | 0.0032 | 0.0199 | 0.025 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0055 | 0.0437 | 0.0433 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0113 | 0.1062 | 0.1405 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0029 | 0.0167 | 0.0163 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.0229 | 0.029 |
Echinococcus multilocularis | epidermal growth factor receptor | 0.0174 | 0.1706 | 0.1814 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0113 | 0.1062 | 0.1405 |
Onchocerca volvulus | 0.0097 | 0.0892 | 0.3417 | |
Mycobacterium tuberculosis | Two component sensor kinase MprB | 0.0018 | 0.0052 | 0.0068 |
Trichomonas vaginalis | two component sensor and regulator histidine kinase bacteria, putative | 0.0024 | 0.0109 | 0.0346 |
Toxoplasma gondii | fructose-bisphospatase I | 0.027 | 0.2731 | 0.3419 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0076 | 0.0666 | 0.0873 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0031 | 0.0189 | 0.0237 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.006 | 0.0498 | 0.1502 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0037 | 0.0254 | 0.0826 |
Echinococcus multilocularis | cpg binding protein | 0.0031 | 0.0187 | 0.019 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0049 | 0.0376 | 0.049 |
Brugia malayi | glutaminase DH11.1 | 0.0298 | 0.3026 | 0.3985 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0137 | 0.0132 |
Brugia malayi | RNA binding protein | 0.0063 | 0.0526 | 0.0688 |
Echinococcus multilocularis | smad | 0.0032 | 0.0199 | 0.0202 |
Brugia malayi | CXXC zinc finger family protein | 0.0029 | 0.0169 | 0.0217 |
Trichomonas vaginalis | sensory transduction histidine kinase bacterial, putative | 0.0024 | 0.0109 | 0.0346 |
Schistosoma mansoni | tyrosine kinase | 0.0093 | 0.085 | 0.111 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.006 | 0.0498 | 0.0651 |
Brugia malayi | hypothetical protein | 0.0049 | 0.0379 | 0.0494 |
Echinococcus granulosus | Smad4 | 0.0032 | 0.0199 | 0.025 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0063 | 0.0526 | 0.0522 |
Trichomonas vaginalis | set domain proteins, putative | 0.0258 | 0.2604 | 0.8603 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0033 | 0.0209 | 0.0263 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0042 | 0.0299 | 0.0976 |
Schistosoma mansoni | TGF-beta signal transducer Smad2 | 0.0032 | 0.0199 | 0.025 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0154 | 0.1499 | 0.1971 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0033 | 0.0209 | 0.0263 |
Echinococcus granulosus | insulin receptor | 0.0056 | 0.0448 | 0.0578 |
Echinococcus multilocularis | fructose 1,6 bisphosphatase 1 | 0.0726 | 0.7587 | 0.81 |
Schistosoma mansoni | tyrosine kinase | 0.0092 | 0.084 | 0.1096 |
Mycobacterium tuberculosis | Possible two component system response sensor kinase membrane associated PhoR | 0.0018 | 0.0052 | 0.0068 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0037 | 0.0254 | 0.846 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0064 | 0.0533 | 0.0691 |
Brugia malayi | mothers against decapentaplegic homolog 3 | 0.0014 | 0.001 | 0.0007 |
Echinococcus multilocularis | insulin receptor | 0.0056 | 0.0448 | 0.0468 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0113 | 0.1062 | 0.3501 |
Onchocerca volvulus | 0.0033 | 0.0209 | 0.0785 | |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0076 | 0.0666 | 0.0873 |
Echinococcus multilocularis | tar DNA binding protein | 0.0063 | 0.0526 | 0.0552 |
Schistosoma mansoni | alpha glucosidase | 0.0037 | 0.0254 | 0.0323 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0042 | 0.0299 | 0.5 |
Brugia malayi | Pre-SET motif family protein | 0.0033 | 0.0209 | 0.0269 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0168 | 0.1648 | 0.2167 |
Onchocerca volvulus | 0.0113 | 0.1062 | 0.4069 | |
Echinococcus granulosus | dnaJ subfamily B | 0.0419 | 0.4313 | 0.5679 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0229 | 0.7624 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0057 | 0.0462 | 0.0343 |
Echinococcus granulosus | Ataxin 2 N terminaldomain containing protein | 0.0034 | 0.022 | 0.0277 |
Echinococcus multilocularis | dnaJ subfamily B | 0.0419 | 0.4313 | 0.46 |
Loa Loa (eye worm) | nuclear factor I | 0.0018 | 0.0046 | 0.0041 |
Echinococcus granulosus | neutral alpha glucosidase AB | 0.0037 | 0.0254 | 0.0323 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0229 | 0.7624 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0113 | 0.1062 | 0.1389 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.006 | 0.0498 | 0.0645 |
Mycobacterium tuberculosis | Conserved protein | 0.0113 | 0.1062 | 0.1405 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0113 | 0.1062 | 0.3501 |
Trichomonas vaginalis | esterase, putative | 0.0113 | 0.1062 | 0.3501 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0033 | 0.0209 | 0.0213 |
Echinococcus multilocularis | TGF beta signal transducer SmadC | 0.0032 | 0.0199 | 0.0202 |
Loa Loa (eye worm) | hypothetical protein | 0.0113 | 0.1062 | 0.1058 |
Loa Loa (eye worm) | beta-lactamase | 0.0113 | 0.1062 | 0.1058 |
Brugia malayi | MH1 domain containing protein | 0.0032 | 0.0199 | 0.0256 |
Echinococcus multilocularis | Ataxin 2, N terminal,domain containing protein | 0.0034 | 0.022 | 0.0225 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.006 | 0.0498 | 0.0645 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0.1608 | 0.1605 |
Schistosoma mansoni | cpg binding protein | 0.0029 | 0.0169 | 0.0211 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0154 | 0.1499 | 0.1495 |
Toxoplasma gondii | glycosyl hydrolase, family 31 protein | 0.0037 | 0.0254 | 0.0061 |
Onchocerca volvulus | 0.0258 | 0.2604 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0209 | 0.0204 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0033 | 0.0209 | 0.0263 |
Echinococcus granulosus | melanoma receptor tyrosine protein kinase | 0.0093 | 0.085 | 0.111 |
Schistosoma mansoni | hypothetical protein | 0.0105 | 0.0979 | 0.128 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0037 | 0.0254 | 0.025 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.0526 | 0.0682 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.0042 | 0.0299 | 0.5 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0145 | 0.1401 | 0.1836 |
Trypanosoma cruzi | sedoheptulose-1,7-bisphosphatase, putative | 0.027 | 0.2731 | 0.3596 |
Loa Loa (eye worm) | TAR-binding protein | 0.0063 | 0.0526 | 0.0522 |
Echinococcus multilocularis | musashi | 0.0055 | 0.0437 | 0.0457 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0113 | 0.1062 | 0.1395 |
Loa Loa (eye worm) | hypothetical protein | 0.0154 | 0.1499 | 0.1495 |
Loa Loa (eye worm) | intermediate filament protein | 0.0055 | 0.0437 | 0.0433 |
Schistosoma mansoni | hypothetical protein | 0.0419 | 0.4313 | 0.5679 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0113 | 0.1062 | 0.1405 |
Loa Loa (eye worm) | glutaminase | 0.0298 | 0.3026 | 0.3023 |
Schistosoma mansoni | intermediate filament proteins | 0.0055 | 0.0437 | 0.0564 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.006 | 0.0498 | 0.1502 |
Plasmodium vivax | FAD-linked sulfhydryl oxidase ERV1, putative | 0.0038 | 0.0264 | 0.0651 |
Schistosoma mansoni | ap endonuclease | 0.0042 | 0.0299 | 0.0382 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.006 | 0.0498 | 0.1502 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0113 | 0.1062 | 0.1395 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.0526 | 0.0682 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0076 | 0.0666 | 1 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0168 | 0.1648 | 0.1751 |
Schistosoma mansoni | tyrosine kinase | 0.0056 | 0.0448 | 0.0578 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0049 | 0.0376 | 0.049 |
Trypanosoma cruzi | Present in the outer mitochondrial membrane proteome 4 | 0.0038 | 0.0264 | 0.0342 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0037 | 0.0254 | 0.0826 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0049 | 0.0376 | 0.0392 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0113 | 0.1062 | 0.3501 |
Schistosoma mansoni | tyrosine kinase | 0.0092 | 0.084 | 0.1096 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0229 | 0.7624 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0014 | 0.001 | 0.0005 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0229 | 0.7624 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0113 | 0.1062 | 0.3501 |
Toxoplasma gondii | exonuclease III APE | 0.0042 | 0.0299 | 0.0123 |
Leishmania major | 0.0726 | 0.7587 | 1 | |
Brugia malayi | fructose-1,6-bisphosphatase | 0.0726 | 0.7587 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.0437 | 0.0433 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.006 | 0.0498 | 0.0645 |
Onchocerca volvulus | Mothers against decapentaplegic homolog | 0.0014 | 0.001 | 0.0019 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0029 | 0.0167 | 0.0215 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0145 | 0.1401 | 0.1836 |
Schistosoma mansoni | ap endonuclease | 0.0042 | 0.0299 | 0.0382 |
Trichomonas vaginalis | maltase-glucoamylase, putative | 0.0037 | 0.0254 | 0.0826 |
Trypanosoma cruzi | ERV/ALR sulfhydryl oxidase domain-containing protein | 0.0038 | 0.0264 | 0.0342 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0113 | 0.1062 | 0.1405 |
Schistosoma mansoni | smad1 5 8 and | 0.0032 | 0.0199 | 0.025 |
Brugia malayi | hypothetical protein | 0.0035 | 0.0229 | 0.0296 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0113 | 0.1062 | 0.1395 |
Schistosoma mansoni | alpha-glucosidase | 0.0145 | 0.1398 | 0.1833 |
Brugia malayi | TAR-binding protein | 0.0063 | 0.0526 | 0.0688 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0035 | 0.0229 | 0.029 |
Loa Loa (eye worm) | RNA binding protein | 0.0063 | 0.0526 | 0.0522 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0035 | 0.0229 | 0.0235 |
Echinococcus multilocularis | geminin | 0.0369 | 0.3781 | 0.4032 |
Mycobacterium tuberculosis | Two component sensor histidine kinase TrcS | 0.0018 | 0.0052 | 0.0068 |
Schistosoma mansoni | hypothetical protein | 0.0049 | 0.0376 | 0.0484 |
Schistosoma mansoni | tyrosine kinase | 0.0093 | 0.085 | 0.111 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0033 | 0.0209 | 0.0213 |
Echinococcus multilocularis | epidermal growth factor receptor | 0.0093 | 0.085 | 0.0899 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0037 | 0.0254 | 0.0826 |
Echinococcus granulosus | GPCR family 2 | 0.0049 | 0.0376 | 0.0484 |
Brugia malayi | Smad1 | 0.0032 | 0.0199 | 0.0256 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0042 | 0.0299 | 0.0389 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0049 | 0.0376 | 0.0392 |
Brugia malayi | Protein kinase domain containing protein | 0.0056 | 0.0448 | 0.0584 |
Trichomonas vaginalis | receptor histidine kinase, putative | 0.0024 | 0.0109 | 0.0346 |
Trichomonas vaginalis | receptor histidine kinase, putative | 0.0024 | 0.0109 | 0.0346 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0042 | 0.0299 | 0.0389 |
Onchocerca volvulus | 0.0055 | 0.0437 | 0.1664 | |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0048 | 0.0368 | 0.0473 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.022 | 0.0277 |
Onchocerca volvulus | 0.0055 | 0.0437 | 0.1664 | |
Onchocerca volvulus | 0.0029 | 0.0169 | 0.0634 | |
Wolbachia endosymbiont of Brugia malayi | signal transduction histidine kinase and receiver | 0.0024 | 0.0109 | 0.2317 |
Brugia malayi | beta-lactamase family protein | 0.0113 | 0.1062 | 0.1395 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0145 | 0.1401 | 0.1841 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0113 | 0.1062 | 0.3398 |
Toxoplasma gondii | Erv1 / Alr family protein | 0.0038 | 0.0264 | 0.0075 |
Echinococcus granulosus | intermediate filament protein | 0.0055 | 0.0437 | 0.0564 |
Echinococcus granulosus | cytoplasmic intermediate filament protein | 0.0026 | 0.0137 | 0.0168 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0076 | 0.0666 | 0.0873 |
Schistosoma mansoni | glutaminase | 0.0298 | 0.3026 | 0.3981 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0037 | 0.0254 | 0.0826 |
Echinococcus multilocularis | mothers against decapentaplegic 5 | 0.0032 | 0.0199 | 0.0202 |
Brugia malayi | MH1 domain containing protein | 0.0018 | 0.0046 | 0.0055 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0042 | 0.0299 | 0.0396 |
Echinococcus granulosus | epidermal growth factor receptor | 0.0174 | 0.1706 | 0.2239 |
Loa Loa (eye worm) | hypothetical protein | 0.0113 | 0.1062 | 0.1058 |
Echinococcus granulosus | TGF beta signal transducer SmadC | 0.0032 | 0.0199 | 0.025 |
Schistosoma mansoni | hypothetical protein | 0.0049 | 0.0376 | 0.0484 |
Echinococcus multilocularis | tumor protein p63 | 0.0328 | 0.3352 | 0.3573 |
Mycobacterium ulcerans | lipase LipD | 0.0113 | 0.1062 | 0.3398 |
Echinococcus granulosus | FAD linked sulfhydryl oxidase ALR | 0.0038 | 0.0264 | 0.0336 |
Onchocerca volvulus | 0.0165 | 0.1608 | 0.6171 | |
Mycobacterium tuberculosis | Possible two component sensor kinase TcrY | 0.0018 | 0.0052 | 0.0068 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0145 | 0.1401 | 0.1836 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0145 | 0.1401 | 0.1836 |
Schistosoma mansoni | hypothetical protein | 0.0049 | 0.0376 | 0.0484 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0076 | 0.0666 | 1 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0113 | 0.1062 | 0.1405 |
Leishmania major | hypothetical protein, conserved | 0.0076 | 0.0666 | 0.0873 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0105 | 0.0979 | 0.1286 |
Brugia malayi | Augmenter of liver regeneration | 0.0038 | 0.0264 | 0.0342 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.0368 | 0.0364 |
Echinococcus multilocularis | Smad4 | 0.0032 | 0.0199 | 0.0202 |
Brugia malayi | MH2 domain containing protein | 0.0472 | 0.4884 | 0.6435 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0049 | 0.0376 | 0.0372 |
Echinococcus multilocularis | FAD linked sulfhydryl oxidase ALR | 0.0038 | 0.0264 | 0.0272 |
Echinococcus granulosus | tar DNA binding protein | 0.0063 | 0.0526 | 0.0682 |
Trypanosoma cruzi | sedoheptulose-1,7-bisphosphatase, putative | 0.027 | 0.2731 | 0.3596 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0042 | 0.0299 | 0.0976 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0168 | 0.1648 | 0.1751 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0037 | 0.0254 | 0.0329 |
Schistosoma mansoni | tyrosine kinase | 0.0056 | 0.0448 | 0.0578 |
Echinococcus granulosus | geminin | 0.0369 | 0.3781 | 0.4978 |
Schistosoma mansoni | cpg binding protein | 0.0031 | 0.0187 | 0.0234 |
Echinococcus granulosus | smad | 0.0032 | 0.0199 | 0.025 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.0526 | 0.0682 |
Brugia malayi | MH1 domain containing protein | 0.0018 | 0.0046 | 0.0055 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.0042 | 0.0299 | 0.0833 |
Brugia malayi | intermediate filament protein | 0.0055 | 0.0437 | 0.057 |
Echinococcus multilocularis | insulin growth factor 1 receptor beta | 0.0056 | 0.0448 | 0.0468 |
Onchocerca volvulus | 0.0048 | 0.0368 | 0.1399 | |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.0426 | 0.0422 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0032 | 0.0199 | 0.0195 |
Brugia malayi | MH2 domain containing protein | 0.0014 | 0.001 | 0.0007 |
Loa Loa (eye worm) | TK/INSR protein kinase | 0.0056 | 0.0448 | 0.0443 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0113 | 0.1062 | 0.3501 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.0042 | 0.0299 | 1 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0042 | 0.0299 | 0.0389 |
Echinococcus multilocularis | cytoplasmic intermediate filament protein | 0.0026 | 0.0137 | 0.0136 |
Brugia malayi | MH2 domain containing protein | 0.0032 | 0.0199 | 0.0256 |
Loa Loa (eye worm) | hypothetical protein | 0.0113 | 0.1062 | 0.1058 |
Mycobacterium ulcerans | beta-lactamase | 0.0113 | 0.1062 | 0.3398 |
Trypanosoma brucei | sedoheptulose-1,7-bisphosphatase | 0.027 | 0.2731 | 0.3596 |
Brugia malayi | MH2 domain containing protein | 0.0032 | 0.0199 | 0.0256 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0154 | 0.1499 | 0.1971 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0032 | 0.0199 | 0.0195 |
Loa Loa (eye worm) | Smad1 | 0.0032 | 0.0199 | 0.0195 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0113 | 0.1062 | 0.1058 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0049 | 0.0376 | 0.0484 |
Trichomonas vaginalis | sucrase-isomaltase, putative | 0.0037 | 0.0254 | 0.0826 |
Echinococcus granulosus | lamin dm0 | 0.0055 | 0.0437 | 0.0564 |
Toxoplasma gondii | ABC1 family protein | 0.0113 | 0.1062 | 0.1157 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0145 | 0.1401 | 0.1836 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0063 | 0.0526 | 0.0688 |
Toxoplasma gondii | sedoheptulose-1,7-bisphosphatase | 0.027 | 0.2731 | 0.3419 |
Leishmania major | alpha glucosidase II subunit, putative | 0.0037 | 0.0254 | 0.0329 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0168 | 0.1648 | 0.1644 |
Brugia malayi | hypothetical protein | 0.0076 | 0.0666 | 0.0873 |
Loa Loa (eye worm) | hypothetical protein | 0.0953 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.0666 | 0.0662 |
Plasmodium vivax | hypothetical protein, conserved | 0.0113 | 0.1062 | 1 |
Echinococcus multilocularis | 0.0054 | 0.0429 | 0.0448 | |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.0526 | 0.0682 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0042 | 0.0299 | 0.0389 |
Loa Loa (eye worm) | hypothetical protein | 0.0113 | 0.1062 | 0.1058 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.0042 | 0.0299 | 1 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0113 | 0.1062 | 0.3398 |
Mycobacterium leprae | conserved hypothetical protein | 0.0113 | 0.1062 | 1 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0037 | 0.0254 | 0.846 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0126 | 0.0122 |
Echinococcus multilocularis | lamin | 0.0055 | 0.0437 | 0.0457 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.