Detailed information for compound 938419

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 391.847 | Formula: C23H18ClNO3
  • H donors: 1 H acceptors: 1 LogP: 4.57 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: Oc1cccc2c1C1c3[n+](C2CC1(c1ccoc1)c1ccoc1)cccc3.[Cl-]
  • InChi: 1S/C23H17NO3.ClH/c25-20-6-3-4-17-19-12-23(15-7-10-26-13-15,16-8-11-27-14-16)22(21(17)20)18-5-1-2-9-24(18)19;/h1-11,13-14,19,22H,12H2;1H
  • InChiKey: FXSFKLQKMZQRKO-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Rattus norvegicus Glutamate NMDA receptor Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0138 0.1532 0.3512
Echinococcus granulosus hypothetical protein 0.0023 0.0036 0.0039
Schistosoma mansoni histamine h1 receptor 0.0023 0.0036 0.0039
Echinococcus multilocularis neuropeptide receptor 0.0023 0.0036 0.0036
Onchocerca volvulus 0.0035 0.0194 0.126
Schistosoma mansoni growth hormone secretagogue receptor 0.0023 0.0036 0.0039
Brugia malayi pregnancy-associated plasma protein-A 0.0035 0.0194 0.0263
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0023 0.0033 0.0044
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0253 1
Schistosoma mansoni hypothetical protein 0.0023 0.0036 0.0039
Echinococcus granulosus neuropeptide receptor 0.0023 0.0036 0.0039
Onchocerca volvulus 0.0023 0.0036 0.0232
Brugia malayi Hypothetical subtilase-type proteinase F21H12.6 in chromosome II 0.0025 0.0059 0.008
Schistosoma mansoni hypothetical protein 0.0023 0.0036 0.0039
Loa Loa (eye worm) hypothetical protein 0.0023 0.0036 0.0048
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0138 0.1532 0.3512
Mycobacterium ulcerans DNA polymerase IV 0.004 0.0253 1
Loa Loa (eye worm) hypothetical protein 0.0023 0.0036 0.0048
Schistosoma mansoni site-1 peptidase (S08 family) 0.0025 0.0059 0.0064
Echinococcus granulosus tm gpcr rhodopsin 0.0023 0.0036 0.0039
Echinococcus granulosus neuropeptide receptor 0.0023 0.0036 0.0039
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0355 0.4363 1
Onchocerca volvulus 0.0023 0.0036 0.0232
Trypanosoma brucei DNA polymerase kappa, putative 0.003 0.0127 0.5008
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0719 0.9093 1
Schistosoma mansoni hypothetical protein 0.0138 0.1535 0.1688
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0023 0.0036 0.0039
Brugia malayi larval opioid receptor 0.0023 0.0036 0.0048
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0023 0.0036 0.0036
Brugia malayi hypothetical protein 0.0023 0.0036 0.0048
Toxoplasma gondii subtilisin SUB9 0.0025 0.0059 0.101
Loa Loa (eye worm) hypothetical protein 0.0023 0.0036 0.0048
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0025 0.0059 0.0134
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0023 0.0036 0.0039
Loa Loa (eye worm) hypothetical protein 0.0023 0.0036 0.0048
Echinococcus multilocularis g protein coupled receptor 0.0023 0.0036 0.0036
Echinococcus granulosus 7TM GPCR rhodopsin 0.0023 0.0036 0.0039
Echinococcus granulosus alpha 1A adrenergic receptor 0.0023 0.0036 0.0039
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0023 0.0033 0.0044
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0032 0.0149 0.0149
Giardia lamblia High cysteine membrane protein Group 2 0.0217 0.2564 1
Brugia malayi AKH receptor 0.0023 0.0036 0.0048
Echinococcus multilocularis Peptidase S8 S53, subtilisin kexin sedolisin 0.0025 0.0059 0.0059
Echinococcus granulosus somatostatin receptor 0.0023 0.0036 0.0039
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0025 0.0059 0.0134
Brugia malayi nuclear receptor NHR-88 0.0023 0.0033 0.0044
Brugia malayi hypothetical protein 0.0035 0.0194 0.0263
Loa Loa (eye worm) hypothetical protein 0.0023 0.0036 0.0048
Loa Loa (eye worm) hypothetical protein 0.0025 0.0059 0.008
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0023 0.0036 0.0039
Onchocerca volvulus 0.0138 0.1535 1
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0025 0.0059 0.0134
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0023 0.0033 0.0036
Echinococcus granulosus Furin 1 0.0138 0.1532 0.1685
Plasmodium falciparum SET domain protein, putative 0.0065 0.0581 1
Loa Loa (eye worm) hypothetical protein 0.0023 0.0033 0.0044
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0023 0.0036 0.0039
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0023 0.0036 0.0036
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0023 0.0036 0.0048
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0023 0.0033 0.0044
Loa Loa (eye worm) hypothetical protein 0.0035 0.0194 0.0263
Toxoplasma gondii subtilisin SUB4 0.0025 0.0059 0.101
Trichomonas vaginalis conserved hypothetical protein 0.0113 0.1207 0.2766
Echinococcus granulosus g protein coupled receptor 0.0023 0.0036 0.0039
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0023 0.0033 0.0033
Echinococcus multilocularis rhodopsin orphan GPCR 0.0023 0.0036 0.0036
Trichomonas vaginalis leucine-rich repeat protein, BspA family 0.0113 0.1207 0.2766
Brugia malayi hypothetical protein 0.0023 0.0036 0.0048
Toxoplasma gondii subtilisin SUB2 0.0025 0.0059 0.101
Echinococcus granulosus fmrfamide receptor 0.0023 0.0036 0.0039
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0023 0.0036 0.0048
Brugia malayi hypothetical protein 0.0035 0.0194 0.0263
Brugia malayi hypothetical protein 0.0023 0.0036 0.0048
Schistosoma mansoni adenoreceptor 0.0023 0.0036 0.0039
Echinococcus multilocularis C type lectin domian containing protein 0.0035 0.0194 0.0193
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0253 1
Schistosoma mansoni neuropeptide receptor 0.0023 0.0036 0.0039
Echinococcus multilocularis neuropeptide s receptor 0.0023 0.0036 0.0036
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0023 0.0036 0.0039
Onchocerca volvulus 0.0035 0.0194 0.126
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0253 1
Chlamydia trachomatis arginine ABC transporter substrate-binding protein ArtJ 0.0023 0.0033 0.5
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0138 0.1532 0.3512
Brugia malayi Sushi domain 0.0035 0.0194 0.0263
Onchocerca volvulus 0.0023 0.0036 0.0232
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0138 0.1532 0.3512
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0253 1
Toxoplasma gondii subtilisin SUB12 0.0025 0.0059 0.101
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0253 1
Brugia malayi neuropeptide F receptor 0.0023 0.0036 0.0048
Echinococcus multilocularis g-protein coupled receptor 0.0023 0.0036 0.0036
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0023 0.0036 0.0036
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0023 0.0036 0.0048
Onchocerca volvulus 0.0023 0.0036 0.0232
Schistosoma mansoni subfamily S8B unassigned peptidase (S08 family) 0.0585 0.7351 0.8084
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0023 0.0036 0.0039
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0025 0.0059 0.0134
Schistosoma mansoni subfamily S8B unassigned peptidase (S08 family) 0.0025 0.0059 0.0064
Schistosoma mansoni steroid hormone receptor ad4bp 0.0023 0.0033 0.0036
Loa Loa (eye worm) G-protein coupled receptor 0.0023 0.0036 0.0048
Loa Loa (eye worm) hypothetical protein 0.0023 0.0036 0.0048
Schistosoma mansoni coup transcription factor 0.0023 0.0033 0.0036
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0023 0.0036 0.0036
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0253 1
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0253 1
Brugia malayi hypothetical protein 0.0023 0.0036 0.0048
Schistosoma mansoni neuropeptide f receptor 76f 0.0023 0.0036 0.0039
Giardia lamblia Furin precursor putative serine protease 0.0113 0.1207 0.4707
Echinococcus multilocularis rhodopsin orphan GPCR 0.0023 0.0036 0.0036
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0025 0.0059 0.0134
Loa Loa (eye worm) hypothetical protein 0.0023 0.0036 0.0048
Echinococcus multilocularis dro:myosuppressin receptor 0.0023 0.0036 0.0036
Trichomonas vaginalis conserved hypothetical protein 0.0113 0.1207 0.2766
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0023 0.0036 0.0039
Echinococcus granulosus biogenic amine 5HT receptor 0.0023 0.0036 0.0039
Echinococcus multilocularis membrane bound transcription factor site 1 0.0025 0.0059 0.0059
Mycobacterium tuberculosis Probable membrane-anchored mycosin MycP3 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-3) 0.0025 0.0059 1
Trichomonas vaginalis WD repeat domain, putative 0.0138 0.1535 0.3519
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0023 0.0033 0.0044
Loa Loa (eye worm) hypothetical protein 0.0023 0.0033 0.0044
Echinococcus granulosus orexin receptor type 2 0.0023 0.0036 0.0039
Loa Loa (eye worm) hypothetical protein 0.0035 0.0194 0.0263
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0023 0.0033 0.0036
Schistosoma mansoni amine GPCR 0.0023 0.0036 0.0039
Echinococcus granulosus rhodopsin orphan GPCR 0.0023 0.0036 0.0039
Mycobacterium tuberculosis Probable membrane-anchored mycosin MycP4 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-4) 0.0025 0.0059 1
Loa Loa (eye worm) hypothetical protein 0.0023 0.0036 0.0048
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0023 0.0036 0.0039
Echinococcus granulosus neuroendocrine convertase 2 0.0367 0.452 0.4971
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0253 1
Brugia malayi Melatonin receptor type 1A 0.0023 0.0036 0.0048
Trypanosoma brucei DNA polymerase IV, putative 0.004 0.0253 1
Loa Loa (eye worm) hypothetical protein 0.0035 0.0194 0.0263
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0023 0.0033 0.0044
Echinococcus multilocularis Furin 1 0.0138 0.1532 0.1532
Schistosoma mansoni serine/threonine protein kinase 0.0092 0.0931 0.1024
Loa Loa (eye worm) hypothetical protein 0.0023 0.0036 0.0048
Brugia malayi Tachykinin-like peptides receptor 99D 0.0023 0.0036 0.0048
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0138 0.1532 0.3512
Echinococcus multilocularis neuropeptides capa receptor 0.0023 0.0036 0.0036
Brugia malayi steroid hormone receptor 0.0023 0.0033 0.0044
Schistosoma mansoni hypothetical protein 0.0034 0.0181 0.0199
Onchocerca volvulus 0.0023 0.0036 0.0232
Echinococcus multilocularis thyroid hormone receptor alpha 0.0145 0.1627 0.1627
Loa Loa (eye worm) hypothetical protein 0.0023 0.0036 0.0048
Schistosoma mansoni histone-lysine n-methyltransferase seto7 0.0065 0.0581 0.0639
Echinococcus multilocularis dna polymerase kappa 0.004 0.0253 0.0253
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0023 0.0036 0.0048
Echinococcus multilocularis rhodopsin orphan GPCR 0.0023 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0023 0.0036 0.0048
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0023 0.0033 0.0033
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0023 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0035 0.0194 0.0263
Mycobacterium ulcerans membrane-anchored serine protease (mycosin), MycP4 0.0025 0.0059 0.1185
Trichomonas vaginalis hypothetical protein 0.0113 0.1207 0.2766
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0025 0.0059 0.0134
Loa Loa (eye worm) hypothetical protein 0.0023 0.0036 0.0048
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0023 0.0033 0.0044
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0023 0.0036 0.0036
Echinococcus multilocularis sex peptide receptor 0.0023 0.0036 0.0036
Trichomonas vaginalis proprotein convertase subtilisin/kexin type, putative 0.0113 0.1207 0.2766
Echinococcus granulosus furin 0.0585 0.7351 0.8084
Echinococcus multilocularis rhodopsin orphan GPCR 0.0023 0.0036 0.0036
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0023 0.0036 0.0048
Echinococcus multilocularis serotonin receptor 0.0023 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0023 0.0033 0.0044
Toxoplasma gondii histone lysine methyltransferase SET8 0.0065 0.0581 1
Brugia malayi Dopamine receptor 0.0023 0.0036 0.0048
Brugia malayi hypothetical protein 0.0023 0.0036 0.0048
Schistosoma mansoni amine GPCR 0.0023 0.0036 0.0039
Echinococcus multilocularis histone lysine n methyltransferase setd8 0.0065 0.0581 0.0581
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0023 0.0033 0.0036
Brugia malayi Membrane-bound transcription factor site-1 protease precursor 0.0025 0.0059 0.008
Onchocerca volvulus 0.0023 0.0036 0.0232
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0025 0.0059 0.0134
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0023 0.0033 0.0036
Echinococcus granulosus allatostatin A receptor 0.0023 0.0036 0.0039
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0023 0.0033 0.0044
Schistosoma mansoni amine GPCR 0.0023 0.0036 0.0039
Onchocerca volvulus 0.0023 0.0036 0.0232
Toxoplasma gondii subtilisin SUB6 0.0025 0.0059 0.101
Loa Loa (eye worm) hypothetical protein 0.0065 0.0581 0.079
Onchocerca volvulus 0.0035 0.0194 0.126
Loa Loa (eye worm) hypothetical protein 0.0023 0.0036 0.0048
Brugia malayi ORL1-like opioid receptor 0.0023 0.0036 0.0048
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0025 0.0059 0.0134
Echinococcus multilocularis beta adrenergic receptor kinase 0.0092 0.0931 0.0931
Echinococcus granulosus C type lectin domian containing protein 0.0035 0.0194 0.0213
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0023 0.0036 0.0039
Echinococcus granulosus ecdysone induced protein 78C 0.0023 0.0033 0.0036
Loa Loa (eye worm) hypothetical protein 0.0023 0.0033 0.0044
Echinococcus multilocularis g protein coupled receptor 0.0023 0.0036 0.0036
Onchocerca volvulus 0.0035 0.0194 0.126
Echinococcus multilocularis g protein coupled receptor 0.0023 0.0036 0.0036
Echinococcus multilocularis fmrfamide receptor 0.0023 0.0036 0.0036
Loa Loa (eye worm) proprotein convertase 2 0.0138 0.1532 0.2084
Loa Loa (eye worm) hypothetical protein 0.0023 0.0036 0.0048
Toxoplasma gondii subtilisin SUB10 0.0025 0.0059 0.101
Loa Loa (eye worm) hypothetical protein 0.0023 0.0036 0.0048
Toxoplasma gondii subtilisin SUB8 0.0025 0.0059 0.101
Trichomonas vaginalis conserved hypothetical protein 0.0113 0.1207 0.2766
Brugia malayi endoprotease bli-4 precursor 0.0585 0.7351 1
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0719 0.9093 0.9093
Trichomonas vaginalis neuroendocrine convertase 2 precursor, putative 0.0113 0.1207 0.2766
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0023 0.0033 0.0044
Trichomonas vaginalis conserved hypothetical protein 0.0113 0.1207 0.2766
Schistosoma mansoni serine/threonine protein kinase 0.0092 0.0931 0.1024
Onchocerca volvulus 0.0023 0.0036 0.0232
Trypanosoma brucei DNA polymerase kappa, putative 0.003 0.0127 0.5008
Loa Loa (eye worm) TYRA-2 protein 0.0023 0.0036 0.0048
Echinococcus multilocularis neuropeptide Y receptor 0.0023 0.0036 0.0036
Loa Loa (eye worm) subtilase 0.0025 0.0059 0.008
Schistosoma mansoni opsin-like receptor 0.0023 0.0036 0.0039
Mycobacterium leprae PROBABLE MEMBRANE-ANCHORED MYCOSIN MYCP3 (SERINE PROTEASE) (SUBTILISIN-LIKE PROTEASE) (SUBTILASE-LIKE) (MYCOSIN-3) 0.0025 0.0059 0.5
Treponema pallidum amino acid ABC transporter, periplasmic binding protein (hisJ) 0.0023 0.0033 1
Toxoplasma gondii subtilisin SUB7 0.0025 0.0059 0.101
Loa Loa (eye worm) hypothetical protein 0.0035 0.0194 0.0263
Loa Loa (eye worm) hypothetical protein 0.0023 0.0036 0.0048
Echinococcus granulosus rhodopsin orphan GPCR 0.0023 0.0036 0.0039
Plasmodium vivax subtilisin-like protease 2, putative 0.0025 0.0059 0.101
Echinococcus granulosus dro:myosuppressin receptor 0.0023 0.0036 0.0039
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0025 0.0059 0.0134
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0355 0.4363 1
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0023 0.0033 0.0036
Loa Loa (eye worm) pigment dispersing factor receptor c 0.005 0.0389 0.0529
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0023 0.0036 0.0039
Loa Loa (eye worm) hypothetical protein 0.0023 0.0036 0.0048
Loa Loa (eye worm) hypothetical protein 0.0023 0.0036 0.0048
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0023 0.0033 0.0036
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0023 0.0036 0.0039
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0059 0.0134
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0023 0.0033 0.0044
Plasmodium vivax apical sushi protein, putative 0.0035 0.0194 0.3331
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0023 0.0033 0.0044
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0023 0.0036 0.0039
Schistosoma mansoni nuclear hormone receptor 0.0023 0.0033 0.0036
Echinococcus multilocularis ecdysone induced protein 78C 0.0023 0.0033 0.0033
Loa Loa (eye worm) hypothetical protein 0.0023 0.0033 0.0044
Brugia malayi ecdysteroid receptor 0.0023 0.0033 0.0044
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0023 0.0033 0.0033
Schistosoma mansoni tripeptidyl-peptidase II (S08 family) 0.0025 0.0059 0.0064
Schistosoma mansoni hypothetical protein 0.0113 0.1207 0.1327
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0025 0.0059 0.0134
Brugia malayi follicle stimulating hormone receptor 0.0023 0.0036 0.0048
Onchocerca volvulus 0.0023 0.0036 0.0232
Echinococcus multilocularis allatostatin A receptor 0.0023 0.0036 0.0036
Echinococcus granulosus neuropeptide Y receptor 0.0023 0.0036 0.0039
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0023 0.0036 0.0039
Echinococcus granulosus g protein coupled receptor 0.0023 0.0036 0.0039
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0025 0.0059 0.0134
Echinococcus granulosus rhodopsin orphan GPCR 0.0023 0.0036 0.0039
Loa Loa (eye worm) hypothetical protein 0.0023 0.0036 0.0048
Trichomonas vaginalis conserved hypothetical protein 0.0113 0.1207 0.2766
Echinococcus multilocularis rhodopsin orphan GPCR 0.0023 0.0036 0.0036
Brugia malayi hypothetical protein 0.0023 0.0036 0.0048
Loa Loa (eye worm) hypothetical protein 0.0023 0.0036 0.0048
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0059 0.0134
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0025 0.0059 0.0134
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0023 0.0033 0.0044
Trichomonas vaginalis DNA polymerase eta, putative 0.004 0.0253 0.058
Echinococcus multilocularis neuropeptide receptor 0.0023 0.0036 0.0036
Schistosoma mansoni thyroid hormone receptor 0.0145 0.1627 0.1789
Brugia malayi Dopamine receptor protein 1 0.0023 0.0036 0.0048
Trichomonas vaginalis conserved hypothetical protein 0.0113 0.1207 0.2766
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0023 0.0036 0.0036
Loa Loa (eye worm) G-protein coupled receptor 0.0023 0.0036 0.0048
Toxoplasma gondii subtilisin SUB1 0.0025 0.0059 0.101
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0122 0.1327 0.1459
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0023 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0035 0.0194 0.0263
Brugia malayi Protein set-1 0.0065 0.0581 0.079
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0023 0.0033 0.0044
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0023 0.0033 0.0033
Schistosoma mansoni retinoic acid receptor RXR 0.0023 0.0033 0.0036
Onchocerca volvulus 0.0035 0.0194 0.126
Brugia malayi hypothetical protein 0.0035 0.0194 0.0263
Loa Loa (eye worm) hypothetical protein 0.0023 0.0036 0.0048
Schistosoma mansoni subfamily S8B non-peptidase homologue (S08 family) 0.0138 0.1532 0.1685
Trichomonas vaginalis conserved hypothetical protein 0.0113 0.1207 0.2766
Echinococcus granulosus protein will die slowly 0.0138 0.1535 0.1688
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0023 0.0033 0.0044
Onchocerca volvulus 0.0035 0.0194 0.126
Echinococcus granulosus G protein coupled receptor 139 0.0023 0.0036 0.0039
Loa Loa (eye worm) hypothetical protein 0.0023 0.0036 0.0048
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0023 0.0036 0.0036
Echinococcus multilocularis protein will die slowly 0.0138 0.1535 0.1535
Brugia malayi G-protein coupled receptor 0.0023 0.0036 0.0048
Echinococcus granulosus peptidase s8 s53 subtilisin kexin sedolisin 0.0025 0.0059 0.0064
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0023 0.0036 0.0039
Mycobacterium ulcerans membrane-anchored mycosin MycP3 0.0025 0.0059 0.1185
Loa Loa (eye worm) endoprotease bli-4 0.0585 0.7351 1
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0023 0.0033 0.0036
Leishmania major subtilisin-like serine peptidase 0.0025 0.0059 1
Trichomonas vaginalis conserved hypothetical protein 0.0113 0.1207 0.2766
Brugia malayi hypothetical protein 0.0035 0.0194 0.0263
Echinococcus multilocularis neuropeptide FF receptor 2 0.0023 0.0036 0.0036
Echinococcus granulosus tm gpcr rhodopsin 0.0023 0.0036 0.0039
Echinococcus granulosus histone lysine n methyltransferase setd8 0.0065 0.0581 0.0639
Brugia malayi hypothetical protein 0.0023 0.0036 0.0048
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0025 0.0059 0.0134
Echinococcus granulosus rhodopsin orphan GPCR 0.0023 0.0036 0.0039
Onchocerca volvulus 0.0023 0.0036 0.0232
Brugia malayi Dopamine receptor protein 2 0.0023 0.0036 0.0048
Echinococcus granulosus biogenic amine 5HT receptor 0.0023 0.0036 0.0039
Onchocerca volvulus 0.0023 0.0036 0.0232
Brugia malayi Calcitonin receptor-like protein seb-1 0.005 0.0389 0.0529
Echinococcus granulosus g-protein coupled receptor 0.0023 0.0036 0.0039
Loa Loa (eye worm) hypothetical protein 0.0023 0.0036 0.0048
Loa Loa (eye worm) hypothetical protein 0.0023 0.0036 0.0048
Loa Loa (eye worm) hypothetical protein 0.0023 0.0036 0.0048
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0253 1
Loa Loa (eye worm) hypothetical protein 0.0023 0.0033 0.0044
Echinococcus granulosus rhodopsin orphan GPCR 0.0023 0.0036 0.0039
Brugia malayi Nuclear hormone receptor-like 1 0.0023 0.0033 0.0044
Echinococcus granulosus peptide allatostatin:somatostatin 0.0023 0.0036 0.0039
Loa Loa (eye worm) hypothetical protein 0.0034 0.0181 0.0246
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0023 0.0033 0.0036
Brugia malayi Serotonin receptor 0.0023 0.0036 0.0048
Loa Loa (eye worm) hypothetical protein 0.0023 0.0036 0.0048
Echinococcus granulosus neuropeptide FF receptor 2 0.0023 0.0036 0.0039
Plasmodium vivax SET domain protein, putative 0.0065 0.0581 1
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0023 0.0036 0.0039
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0023 0.0033 0.0036
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0023 0.0036 0.0039
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0023 0.0036 0.0039
Schistosoma mansoni neuropeptide receptor 0.0023 0.0036 0.0039
Plasmodium falciparum subtilisin-like protease 1 0.0025 0.0059 0.101
Echinococcus granulosus rhodopsin orphan GPCR 0.0023 0.0036 0.0039
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0023 0.0036 0.0036
Schistosoma mansoni myosin xvIII 0.0023 0.0036 0.0039
Onchocerca volvulus 0.0035 0.0194 0.126
Echinococcus multilocularis G-protein coupled receptor, putative 0.0023 0.0036 0.0036
Schistosoma mansoni biogenic amine receptor 0.0023 0.0036 0.0039
Mycobacterium tuberculosis Probable alanine and proline rich membrane-anchored mycosin MycP2 (serine protease) (subtilisin-like protease) (subtilase-like) 0.0025 0.0059 1
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0059 0.0134
Brugia malayi celfurPC protein 0.0472 0.5877 0.7995
Loa Loa (eye worm) hypothetical protein 0.0023 0.0036 0.0048
Loa Loa (eye worm) hypothetical protein 0.0585 0.7351 1
Echinococcus granulosus dna polymerase kappa 0.004 0.0253 0.0278
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0025 0.0059 0.0134
Schistosoma mansoni neuropeptide F-like receptor 0.0023 0.0036 0.0039
Plasmodium falciparum apical sushi protein 0.0035 0.0194 0.3331
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0023 0.0033 0.0044
Echinococcus multilocularis rhodopsin orphan GPCR 0.0023 0.0036 0.0036
Onchocerca volvulus 0.0023 0.0036 0.0232
Echinococcus granulosus nmda type glutamate receptor 0.0032 0.0149 0.0164
Plasmodium falciparum subtilisin-like protease 3 0.0025 0.0059 0.101
Brugia malayi G protein-coupled receptor 0.0023 0.0036 0.0048
Toxoplasma gondii subtilisin SUB11 0.0025 0.0059 0.101
Trichomonas vaginalis conserved hypothetical protein 0.0113 0.1207 0.2766
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0059 0.0134
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0025 0.0059 0.0134
Echinococcus granulosus tm gpcr rhodopsin 0.0023 0.0036 0.0039
Trypanosoma brucei subtilisin peptidase 0.0025 0.0059 0.2322
Echinococcus granulosus G protein coupled receptor kinase 1 0.0082 0.0807 0.0888
Echinococcus multilocularis G protein coupled receptor 139 0.0023 0.0036 0.0036
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0025 0.0059 0.0134
Entamoeba histolytica elongation factor-2 kinase, putative 0.002 0 0.5
Mycobacterium ulcerans DNA polymerase IV 0.004 0.0253 1
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0253 1
Mycobacterium leprae Possible secreted protease 0.0025 0.0059 0.5
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0023 0.0033 0.0044
Brugia malayi nuclear hormone receptor 0.0023 0.0033 0.0044
Brugia malayi RE15519p 0.0023 0.0036 0.0048
Brugia malayi Subtilase family protein 0.0025 0.0059 0.008
Loa Loa (eye worm) hypothetical protein 0.0023 0.0036 0.0048
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0025 0.0059 0.0134
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0025 0.0059 0.0134
Echinococcus multilocularis rhodopsin orphan GPCR 0.0023 0.0036 0.0036
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0023 0.0036 0.0039
Trypanosoma brucei DNA polymerase IV, putative 0.0034 0.017 0.67
Brugia malayi GnHR receptor homolog 0.0023 0.0036 0.0048
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0025 0.0059 0.0134
Loa Loa (eye worm) hypothetical protein 0.0023 0.0036 0.0048
Brugia malayi hypothetical protein 0.0023 0.0036 0.0048
Echinococcus multilocularis fmrfamide receptor 0.0023 0.0036 0.0036
Mycobacterium leprae PROBABLE PROLINE RICH MEMBRANE-ANCHORED MYCOSIN MYCP5 (SERINE PROTEASE) (SUBTILISIN-LIKE PROTEASE) (SUBTILASE-LIKE) (MYCOSIN-5) 0.0025 0.0059 0.5
Loa Loa (eye worm) hypothetical protein 0.0023 0.0036 0.0048
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0023 0.0036 0.0036
Chlamydia trachomatis glutamine binding protein 0.0023 0.0033 0.5
Schistosoma mansoni biogenic amine (5HT) receptor 0.0023 0.0036 0.0039
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0059 0.0134
Loa Loa (eye worm) hypothetical protein 0.0023 0.0036 0.0048
Echinococcus multilocularis proprotein convertase subtilisin:kexin type 5 0.0355 0.4363 0.4363
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0023 0.0036 0.0048
Onchocerca volvulus Protein ultraspiracle homolog 0.0023 0.0033 0.0213
Loa Loa (eye worm) hypothetical protein 0.005 0.0389 0.0529
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0138 0.1532 0.3512
Toxoplasma gondii subtilisin SUB5 0.0025 0.0059 0.101
Schistosoma mansoni biogenic amine (5HT) receptor 0.0023 0.0036 0.0039
Loa Loa (eye worm) hypothetical protein 0.0023 0.0036 0.0048
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0719 0.9093 1
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0025 0.0059 0.0134
Loa Loa (eye worm) hypothetical protein 0.0023 0.0036 0.0048
Brugia malayi proprotein convertase 2 0.0367 0.452 0.6149
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0023 0.0036 0.0232
Brugia malayi neuropeptide F receptor 0.0023 0.0036 0.0048
Brugia malayi sulfakinin receptor protein 0.0023 0.0036 0.0048
Brugia malayi hypothetical protein 0.0035 0.0194 0.0263
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0023 0.0033 0.0044
Loa Loa (eye worm) hypothetical protein 0.0023 0.0036 0.0048
Loa Loa (eye worm) hypothetical protein 0.0023 0.0036 0.0048
Loa Loa (eye worm) hypothetical protein 0.0023 0.0036 0.0048
Echinococcus multilocularis rhodopsin orphan GPCR 0.0023 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0023 0.0036 0.0048
Echinococcus multilocularis c4b binding protein beta chain 0.0035 0.0194 0.0193
Schistosoma mansoni amine GPCR 0.0023 0.0036 0.0039
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.004 0.0253 0.058
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.005 0.0389 0.0529
Schistosoma mansoni neuropeptide receptor 0.0023 0.0036 0.0039
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0023 0.0036 0.0036
Onchocerca volvulus 0.0025 0.0059 0.0382
Onchocerca volvulus 0.0023 0.0036 0.0232
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0023 0.0033 0.0044
Echinococcus granulosus membrane bound transcription factor site 1 0.0025 0.0059 0.0064
Schistosoma mansoni neuropeptide F-like receptor 0.0023 0.0036 0.0039
Schistosoma mansoni alpha-1 adrenergic receptor 0.0023 0.0036 0.0039
Brugia malayi Serotonin receptor 0.0023 0.0036 0.0048
Echinococcus granulosus rhodopsin orphan GPCR 0.0023 0.0036 0.0039
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0253 1
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0023 0.0036 0.0048
Schistosoma mansoni furin-1 (S08 family) 0.0254 0.3047 0.335
Schistosoma mansoni thyroid hormone receptor 0.0145 0.1627 0.1789
Onchocerca volvulus 0.0023 0.0036 0.0232
Echinococcus granulosus 7tm_1 domain containing protein 0.0023 0.0036 0.0039
Echinococcus granulosus c4b binding protein beta chain 0.0035 0.0194 0.0213
Brugia malayi GCC2 and GCC3 family protein 0.0035 0.0194 0.0263
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0023 0.0036 0.0048
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0023 0.0036 0.0039
Brugia malayi Steroid receptor seven-up type 2 0.0023 0.0033 0.0044
Mycobacterium tuberculosis Probable glutamine-binding lipoprotein GlnH (GLNBP) 0.0023 0.0033 0.5557
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0025 0.0059 0.0134
Onchocerca volvulus Bile acid receptor homolog 0.0023 0.0033 0.0213
Toxoplasma gondii rhoptry neck protein RON9 0.0035 0.0194 0.3331
Echinococcus granulosus tachykinin peptides receptor 99D 0.0023 0.0036 0.0039
Loa Loa (eye worm) steroid hormone receptor 0.0023 0.0033 0.0044
Echinococcus multilocularis G protein coupled receptor kinase 1 0.0082 0.0807 0.0807
Brugia malayi neuroendocrine convertase 1 precursor 0.0367 0.452 0.6149
Echinococcus granulosus FTZ F1 alpha 0.0023 0.0033 0.0036
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0023 0.0036 0.0036
Echinococcus multilocularis serotonin receptor 0.0023 0.0036 0.0036
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0023 0.0033 0.0036
Mycobacterium ulcerans proline rich membrane-anchored mycosin MycP5 0.0025 0.0059 0.1185
Onchocerca volvulus 0.0023 0.0036 0.0232
Onchocerca volvulus 0.0035 0.0194 0.126
Echinococcus granulosus proprotein convertase subtilisin:kexin type 5 0.0355 0.4363 0.4798
Trypanosoma brucei unspecified product 0.0034 0.017 0.67
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0023 0.0033 0.0036
Brugia malayi putative neuropeptide receptor NPR1 0.0023 0.0036 0.0048
Echinococcus granulosus beta-adrenergic receptor kinase 0.0092 0.0931 0.1024
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0023 0.0036 0.0039
Echinococcus granulosus neuropeptides capa receptor 0.0023 0.0036 0.0039
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0253 1
Echinococcus multilocularis orexin receptor type 2 0.0023 0.0036 0.0036
Schistosoma mansoni RAR-like nuclear receptor 0.0023 0.0033 0.0036
Schistosoma mansoni hypothetical protein 0.0023 0.0036 0.0039
Schistosoma mansoni biogenic amine receptor 0.0023 0.0036 0.0039
Loa Loa (eye worm) neuropeptide F receptor 0.0023 0.0036 0.0048
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0023 0.0033 0.0033
Entamoeba histolytica hypothetical protein, conserved 0.002 0 0.5
Echinococcus multilocularis neuroendocrine convertase 2 0.0367 0.452 0.452
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0023 0.0036 0.0048
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0025 0.0059 0.0134
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0023 0.0033 0.0044
Loa Loa (eye worm) hypothetical protein 0.0023 0.0033 0.0044
Schistosoma mansoni opsin-like receptor 0.0023 0.0036 0.0039
Loa Loa (eye worm) WD40 repeat protein 0.0138 0.1535 0.2089
Echinococcus granulosus serotonin receptor 0.0023 0.0036 0.0039
Onchocerca volvulus 0.0023 0.0036 0.0232
Echinococcus multilocularis neuropeptide receptor A26 0.0023 0.0036 0.0036
Echinococcus multilocularis somatostatin receptor 0.0023 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0229 0.2721 0.3702
Echinococcus multilocularis 0.0472 0.5877 0.5877
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0092 0.0931 0.1267
Brugia malayi Will die slowly protein 0.0138 0.1535 0.2089
Loa Loa (eye worm) hypothetical protein 0.0023 0.0036 0.0048
Echinococcus multilocularis neuropeptides capa receptor 0.0023 0.0036 0.0036
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0023 0.0033 0.0036
Schistosoma mansoni site-1 peptidase (S08 family) 0.0025 0.0059 0.0064
Brugia malayi hypothetical protein 0.0023 0.0036 0.0048
Loa Loa (eye worm) hypothetical protein 0.0023 0.0036 0.0048
Brugia malayi G-protein coupled receptor 0.0023 0.0036 0.0048
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0023 0.0036 0.0039
Echinococcus multilocularis neuropeptide Y receptor 0.0023 0.0036 0.0036
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0122 0.1327 0.1327
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0023 0.0033 0.0036
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0023 0.0036 0.0039
Brugia malayi photoreceptor-specific nuclear receptor 0.0023 0.0033 0.0044
Loa Loa (eye worm) hypothetical protein 0.0023 0.0036 0.0048
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0023 0.0036 0.0039
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0023 0.0033 0.0044
Loa Loa (eye worm) hypothetical protein 0.0035 0.0194 0.0263
Loa Loa (eye worm) neuropeptide F receptor 0.0023 0.0036 0.0048
Brugia malayi putative neuropeptide receptor 0.0023 0.0036 0.0048
Brugia malayi G protein-coupled receptor F59B2.13 0.0023 0.0036 0.0048
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0025 0.0059 0.0134
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0023 0.0033 0.0033
Loa Loa (eye worm) hypothetical protein 0.003 0.0127 0.0172
Echinococcus multilocularis nmda type glutamate receptor 0.0032 0.0149 0.0149
Schistosoma mansoni opsin-like receptor 0.0023 0.0036 0.0039
Onchocerca volvulus 0.0023 0.0036 0.0232
Trypanosoma brucei DNA polymerase IV, putative 0.004 0.0253 1
Echinococcus granulosus neuropeptide s receptor 0.0023 0.0036 0.0039
Entamoeba histolytica hypothetical protein, conserved 0.002 0 0.5
Loa Loa (eye worm) hypothetical protein 0.0035 0.0194 0.0263
Brugia malayi latrophilin 2 splice variant baaae 0.0034 0.0181 0.0246
Treponema pallidum amino acid ABC transporter, periplasmic binding protein 0.0023 0.0033 1
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0253 1
Schistosoma mansoni biogenic amine receptor 0.0023 0.0036 0.0039
Schistosoma mansoni amine GPCR 0.0023 0.0036 0.0039
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0023 0.0036 0.0039
Loa Loa (eye worm) hypothetical protein 0.0023 0.0033 0.0044
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0023 0.0033 0.0044
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0023 0.0036 0.0048
Brugia malayi hypothetical protein 0.0035 0.0194 0.0263
Onchocerca volvulus 0.0035 0.0194 0.126
Loa Loa (eye worm) hypothetical protein 0.0035 0.0194 0.0263
Schistosoma mansoni c4b-binding protein beta chain 0.0035 0.0194 0.0213
Schistosoma mansoni hypothetical protein 0.0023 0.0036 0.0039
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0023 0.0036 0.0039
Echinococcus granulosus neuropeptides capa receptor 0.0023 0.0036 0.0039
Onchocerca volvulus Neuropeptide F receptor homolog 0.0023 0.0036 0.0232
Trypanosoma brucei serine peptidase, clan SB, family S8-like protein 0.0025 0.0059 0.2322
Loa Loa (eye worm) hypothetical protein 0.0023 0.0036 0.0048
Onchocerca volvulus 0.0035 0.0194 0.126
Echinococcus multilocularis FTZ F1 alpha 0.0023 0.0033 0.0033
Echinococcus granulosus neuropeptide Y receptor 0.0023 0.0036 0.0039
Onchocerca volvulus 0.0023 0.0033 0.0213
Mycobacterium tuberculosis Probable proline rich membrane-anchored mycosin MycP5 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-5) 0.0025 0.0059 1
Echinococcus granulosus g protein coupled receptor 0.0023 0.0036 0.0039
Brugia malayi polk-prov protein 0.003 0.0127 0.0172
Toxoplasma gondii rhoptry neck protein RON1 0.0035 0.0194 0.3331
Schistosoma mansoni hypothetical protein 0.0122 0.1327 0.1459
Entamoeba histolytica hypothetical protein 0.002 0 0.5
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0025 0.0059 0.0134
Trichomonas vaginalis conserved hypothetical protein 0.0113 0.1207 0.2766
Loa Loa (eye worm) pregnancy-associated plasma protein-E 0.0035 0.0194 0.0263
Loa Loa (eye worm) hypothetical protein 0.0023 0.0036 0.0048
Echinococcus granulosus sex peptide receptor 0.0023 0.0036 0.0039
Plasmodium vivax subtilisin-like serine protease, putative 0.0025 0.0059 0.101
Brugia malayi hypothetical protein 0.0035 0.0194 0.0263
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0023 0.0033 0.0213
Echinococcus granulosus neuropeptide receptor A26 0.0023 0.0036 0.0039
Brugia malayi hypothetical protein 0.0023 0.0036 0.0048
Schistosoma mansoni neuropeptide receptor 0.0023 0.0036 0.0039
Trichomonas vaginalis conserved hypothetical protein 0.0113 0.1207 0.2766
Plasmodium vivax subtilisin-like protease 1 0.0025 0.0059 0.101
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0023 0.0036 0.0039
Loa Loa (eye worm) melatonin receptor type 1A 0.0023 0.0036 0.0048
Loa Loa (eye worm) hypothetical protein 0.0023 0.0036 0.0048
Loa Loa (eye worm) hypothetical protein 0.0023 0.0036 0.0048
Loa Loa (eye worm) hypothetical protein 0.0023 0.0036 0.0048
Plasmodium falciparum subtilisin-like protease 2 0.0025 0.0059 0.101

Activities

Activity type Activity value Assay description Source Reference
Ki (binding) = 1.8 nM Affinity against 3[H]TCP binding to N-methyl-D-aspartate glutamate receptor in rat brain membranes ChEMBL. 7658445

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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