TDR Targets

Detailed view for OVOC9796

Basic information

TDR Targets ID: 990280
Onchocerca volvulus,
Source Database / ID: Wormbase Parasite

pI: 7.8271 | Length (AA): 354 | MW (Da): 39386 | Paralog Number: 0

Signal peptide: N | GPI Anchor: | Predicted trans-membrane segments: 0

Druggability Group : DG2

Targets have been classified into druggability groups (DG) according to their druggability score in network driven prioritizations. DGs range from 1 to 5; the higher the group number, the higher the chance of the target to be druggable

Network

Pfam domains

PF00122
PF00689
PF00690
PF00702

Gene Ontology

Mouse over links to read term descriptions.

GO:0016021 integral to membrane
GO:0046872 metal ion binding
GO:0000166 nucleotide binding

Metabolic Pathways

cGMP-PKG signaling pathway (KEGG)
cAMP signaling pathway (KEGG)
Cardiac muscle contraction (KEGG)
Adrenergic signaling in cardiomyocytes (KEGG)
Insulin secretion (KEGG)
Thyroid hormone synthesis (KEGG)
Thyroid hormone signaling pathway (KEGG)
Aldosterone-regulated sodium reabsorption (KEGG)
Endocrine and other factor-regulated calcium reabsorption (KEGG)
Proximal tubule bicarbonate reclamation (KEGG)
Salivary secretion (KEGG)
Gastric acid secretion (KEGG)
Pancreatic secretion (KEGG)
Carbohydrate digestion and absorption (KEGG)
Protein digestion and absorption (KEGG)
Bile secretion (KEGG)
Mineral absorption (KEGG)

Structural information

Modbase 3D models:

There are 3 models calculated for this protein. More info on these models, including the models themselves is available at: Modbase

Target Beg	Target End	Template	Template Beg	Template End	Identity	Evalue	Model Score	MPQS	zDope
55	1094	3wgu (A)	25	1016	30.00	0	1	1.20314	0.34
55	1084	2zxe (A)	32	1013	35.00	0	1	1.2005	0.43
197	307	2hc8 (A)	229	326	33.00	0.0024	0.32	0.327463	-0.02

Help me make sense of these data.

Target Beg: first modeled residue
Target End: last modeled residue
Template: template structure used for modelling (PDB accession and chain)
Template Beg: first template residue in target-template alignment
Template End: last template residue in target-template alignment
Identity: sequence identity
Evalue: E value for target-template hit
Model Score: GA341 score (>0.7 for reliable model)
MPQS: ModPipe Quality Score (>1.1 for reliable model)
zDope: zDope Score (negative for reliable model)

A more detailed description of these scores is available at the Modbase Model Evaluation Help Pages, and in the papers referenced therein.

PDB Structures:

No structure availble in the PDB for this protein

Expression

No expression data available for this gene

Orthologs

Ortholog group members (OG5_127003)

Species	Accession	Gene Product
Brugia malayi	Bm1_42845	Sodium/potassium-transporting ATPase alpha chain, putative
Brugia malayi	Bm1_51740	Na,K-ATPase alpha subunit
Candida albicans	CaO19.10084	similar to Pichia farinosa Acu1p, putative P-type ATPase involved in high affinity uptake of potassium or sodium (CAF22247)
Candida albicans	CaO19.2552	similar to Pichia farinosa Acu1p, putative P-type ATPase involved in high affinity uptake of potassium or sodium (CAF22247)
Caenorhabditis elegans	CELE_Y105E8A.12	Protein CATP-1, isoform A
Caenorhabditis elegans	CELE_C09H5.2	Protein CATP-3, isoform B
Caenorhabditis elegans	CELE_B0365.3	Protein EAT-6
Caenorhabditis elegans	CELE_C01G12.8	Protein CATP-4
Caenorhabditis elegans	CELE_C02E7.1	Protein CATP-2
Dictyostelium discoideum	DDB_G0267924	Na+/K+ ATPase
Dictyostelium discoideum	DDB_G0277269	ATPase, P-type cation exchange, alpha subunit
Drosophila melanogaster	Dmel_CG45760	CG45760 gene product from transcript CG45760-RB
Drosophila melanogaster	Dmel_CG5670	Na pump alpha subunit
Echinococcus granulosus	EgrG_000342600	Na:K ATPase alpha subunit
Echinococcus multilocularis	EmuJ_000342600	Na+:K+ ATPase alpha subunit
Giardia lamblia	GL50803_96670	Potassium-transporting ATPase alpha chain 1
Homo sapiens	ENSG00000132681	ATPase, Na+/K+ transporting, alpha 4 polypeptide
Homo sapiens	ENSG00000075673	ATPase, H+/K+ transporting, nongastric, alpha polypeptide
Homo sapiens	ENSG00000018625	ATPase, Na+/K+ transporting, alpha 2 polypeptide
Homo sapiens	ENSG00000105675	ATPase, H+/K+ exchanging, alpha polypeptide
Homo sapiens	ENSG00000105409	ATPase, Na+/K+ transporting, alpha 3 polypeptide
Homo sapiens	ENSG00000163399	ATPase, Na+/K+ transporting, alpha 1 polypeptide
Loa Loa (eye worm)	LOAG_12371	hypothetical protein
Loa Loa (eye worm)	LOAG_06053	sodium/potassium-transporting ATPase subunit alpha
Loa Loa (eye worm)	LOAG_08751	hypothetical protein
Loa Loa (eye worm)	LOAG_07482	hypothetical protein
Loa Loa (eye worm)	LOAG_07650	Na,K-ATPase alpha subunit
Loa Loa (eye worm)	LOAG_08750	hypothetical protein
Mycobacterium leprae	ML2671	PROBABLE CATION-TRANSPORTER ATPASE I CTPI
Mus musculus	ENSMUSG00000040907	ATPase, Na+/K+ transporting, alpha 3 polypeptide
Mus musculus	ENSMUSG00000033161	ATPase, Na+/K+ transporting, alpha 1 polypeptide
Mus musculus	ENSMUSG00000007097	ATPase, Na+/K+ transporting, alpha 2 polypeptide
Mus musculus	ENSMUSG00000005553	ATPase, H+/K+ exchanging, gastric, alpha polypeptide
Mus musculus	ENSMUSG00000007107	ATPase, Na+/K+ transporting, alpha 4 polypeptide
Mus musculus	ENSMUSG00000022229	ATPase, H+/K+ transporting, nongastric, alpha polypeptide
Mycobacterium ulcerans	MUL_1254	metal cation transporter p-type ATPase a
Onchocerca volvulus	OVOC9796
Schistosoma japonicum	Sjp_0112320	Sodium/potassium-transporting ATPase subunit alpha, putative
Schistosoma japonicum	Sjp_0108170	Sodium/potassium-transporting ATPase subunit alpha, putative
Schistosoma japonicum	Sjp_0109810	Sodium/potassium-transporting ATPase subunit alpha-1 precursor, putative
Schistosoma japonicum	Sjp_0016550	ko:K01538 Na+/K+-exchanging ATPase [EC3.6.3.9], putative
Schistosoma japonicum	Sjp_0307290	Sodium/potassium-transporting ATPase subunit alpha, putative
Schistosoma japonicum	Sjp_0016460	Sodium/potassium-transporting ATPase subunit alpha, putative
Schistosoma mansoni	Smp_015020	Na+/K+ transporting ATPase subunit alpha
Schistosoma mansoni	Smp_130300	na+/k+ atpase alpha subunit
Schmidtea mediterranea	mk4.000996.10
Schmidtea mediterranea	mk4.000996.07	JYalpha
Schmidtea mediterranea	mk4.000996.09
Schmidtea mediterranea	mk4.021250.00	Sodium/potassium-transporting ATPase subunit alpha
Schmidtea mediterranea	mk4.007750.02
Schmidtea mediterranea	mk4.001001.04
Schmidtea mediterranea	mk4.000665.02
Schmidtea mediterranea	mk4.010072.00
Schmidtea mediterranea	mk4.019335.00	Sodium/potassium-transporting ATPase subunit alpha
Schmidtea mediterranea	mk4.003370.00	Non-gastric H,K+-ATPase alpha subunit
Schmidtea mediterranea	mk4.003370.02
Schmidtea mediterranea	mk4.001001.01	Sodium/potassium-transporting ATPase subunit alpha
Schmidtea mediterranea	mk4.019335.02
Schmidtea mediterranea	mk4.019335.01
Schmidtea mediterranea	mk4.003370.01	JYalpha
Schmidtea mediterranea	mk4.013441.00
Schmidtea mediterranea	mk4.000529.01
Schmidtea mediterranea	mk4.000996.11

Essentiality

OVOC9796 has one or more orthologs with essentiality data

Gene/Ortholog	Organism	Phenotype	Source Study
CELE_B0365.3	Caenorhabditis elegans	embryonic lethal	wormbase
CELE_B0365.3	Caenorhabditis elegans	larval arrest	wormbase
CELE_B0365.3	Caenorhabditis elegans	slow growth	wormbase
CELE_B0365.3	Caenorhabditis elegans	sterile	wormbase

Show/Hide essentiality data references

goodall

The Essential Genome of Escherichia coli K-12 (Transposon directed high-throughput mutagenesis)

Goodall, Emily CA, et al. "The essential genome of Escherichia coli K-12." mBio 9.1 (2018): e02096-17.

sidik

A Genome-wide CRISPR Screen in Toxoplasma Identifies Essential Apicomplexan Genes.

Sidik, Saima M., et al. "A genome-wide CRISPR screen in toxoplasma identifies essential apicomplexan genes." Cell 166.6 (2016): 1423-1435.

keio

Systematic single-gene knock-out mutants of E. coli K12

The Keio Collection

neb

C. elegans RNAi phenotypes

Data obtained from Wormbase WS150, curated by K. Chaudary and T. Carlow, New England Biolabs

alsford

High-throughput phenotyping using parallel sequencing of RNA interference targets in the African trypanosome

Genome Res 2011, 21:915-924

nmpdr

Genome-scale essentiality datasets from published studies (M. tuberculosis)

National Microbial Pathogen Data Resource

gerdes

Experimental determination and system-level analysis of essential genes in E. coli MG1655

Gerdes et al., J Bacteriol. 2003 185:5673-84

blattner

Systematic mutagenesis of the E. coli (MG1655) genome

J Bacteriol 2004, 186:4921-4930

plasmo

Functional Profiling of a Plasmodium Genome Reveals an Abundance of Essential Genes.

Bushell, Ellen, et al. "Functional profiling of a Plasmodium genome reveals an abundance of essential genes." Cell 170.2 (2017): 260-272.

yeastgenome

Systematic deletion of yeast genes

Saccharomyces Genome Database

wormbase

C. elegans RNAi experiments

WormBase web site, http://www.wormbase.org, release WS170

shigen

Profiling of E. coli Chromosome (PEC)

National Institute of Genetics, Japan

Phenotypes and Validation (curated)

We have no manually annotated phenotypes for this target. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please contact us.

Annotated validation

No validation data for this target

Associated compounds / Druggability

Known modulators for this target

No chemical compounds associated to this gene

Predicted associations

By orthology with druggable targets

Species	Known druggable target	Linked compounds	Reference
Sus scrofa	Potassium-transporting ATPase alpha chain 1	Compounds	References
Homo sapiens	ATPase, Na+/K+ transporting, alpha 3 polypeptide	Compounds	References
Homo sapiens	ATPase, H+/K+ transporting, nongastric, alpha polypeptide	Compounds	References
Homo sapiens	ATPase, Na+/K+ transporting, alpha 2 polypeptide	Compounds	References
Homo sapiens	ATPase, Na+/K+ transporting, alpha 1 polypeptide	Compounds	References
Homo sapiens	ATPase, H+/K+ exchanging, alpha polypeptide	Compounds	References
Rattus norvegicus	Sodium/potassium-transporting ATPase alpha-1 chain	Compounds	References
Canis lupus familiaris	Sodium/potassium-transporting ATPase alpha-1 chain	Compounds	References
Sus scrofa	Sodium/potassium-transporting ATPase alpha-1 chain	Compounds	References

By sequence similarity to non orthologous druggable targets

No additional associated druggable targets

Ranking Plot

Putative Drugs List

Raw	Global	Species
0.0053	0.4509	0.4294
0.0128	0.4305	0
0.0038	0.4305	0.3925
0.0762	0.5656	0
0.0049	0.3517	0
0.0129	0.4751	0.4315
0.039	0.43	1
0.0166	0.5576	0
0.0106	0.4305	0
0.0092	0.2729	0
0.0038	0.427	0.5
0.0384	1	0.5
0.0264	0.4305	0
0.0124	0.5754	0
0.0145	0.3194	0.3194
0.0331	0.4889	0.4826
0.0131	0.4419	0.4147
0.4048	0.4402	0.4401
0.0136	0.3919	1
0.0992	0.6064	0
0.0036	0.3093	0
0.003	0.4305	0
0.0091	0.4539	0
0.0345	0.2809	0
0.0709	0.5651	0
0.0208	0.2533	0.4224
0.028	0.3981	0.652
0.0379	0.5454	0.6365
0.0487	0.3446	0
0.0115	0.2844	0
0.0356	0.2598	0.5771
0.0092	0.4509	0.4321
0.0512	0.5476	0.6655
0.0302	0.5852	0
0.0727	0.3407	0
0.0470888	0.360099	0
0.0215	0.5613	0.5613
0.0131	0.4305	0
0.013	0.4305	0
0.0239	0.9798	0.5
0.0408	0.4305	0
0.0355	0.3324	0.3296
0.0045	0.5576	0
0.0063	0.4305	0
0.0038	0.4305	0
0.0095	0.4305	0
0.0168	0.4243	0.4083
0.0442	0.442	0
0.0318	0.3402	1
0.0215	0.5613	0.5613
0.0099	0.4407	0.4188
0.0217	0.2531	0.9224
0.0234	0.6275	0.6256
0.0222	0.2579	0.722
0.0168	0.4481	0
0.052	0.3725	0.4891
0.0096	0.979	0.5
0.0095	0.4305	0
0.0166	0.2851	0
0.006	0.3981	0
0.0161	0.4305	0
0.0259	0.4775	0.4727
0.0624	0.4305	0
0.0204	0.3411	0.3848
0.0071	0.4305	0
0.005	0.4539	0
0.0443	0.5576	0
0.0857	0.6057	0
0.0384	1	0.5
0.0563	0.5637	0
0.0103	0.2689	0
0.0411	0.4305	0
0.009	0.2665	0.3046
0.0374	0.4305	0
0.0727	0.3407	0
0.0906	0.4282	0.6461
0.02	0.4305	0.1782
0.0622	0.3537	0
0.0138	0.2834	0
0.0322	0.2826	0.6106
0.0146	0.3564	0
0.0404	0.3339	0
0.0042	0.7715	0
0.0086	0.4451	1
0.0133	0.3364	0
0.0029	0.5576	0
0.0038	0.4305	0
0.0074	0.5754	0
0.0042	0.4851	0
0.0134	0.4305	0
0.0186	0.7472	0.743
0.0157	0.4139	0.6082
0.091	0.5689	0
0.1	0.4305	0
0.0038	0.4305	0
0.0618	0.4881	0.4826
0.0064	0.4305	0
0.03	0.4305	0
0.0097	0.5676	0
0.0035	0.436	0
0.0038	0.4305	0
0.0162	0.4305	0
0.0621	0.6034	0
0.0868	0.5663	0
0.0235	0.4243	0
0.0028	0.411	0.3736
0.0366	0.4305	0
0.0684	0.6256	0.6183
0.0593	0.4365	0.4901
0.0254	0.4305	0
0.0437	0.4324	0
0.0353	0.4514	0
0.0323	0.4305	0
0.0017	0.5576	0
0.016	0.4305	0
0.0102	0.4305	0
0.005	1	1
0.0042	0.5273	0
0.0035	0.4243	0.346
0.0304	0.436	0
0.0038	0.4305	0
0.0133	0.4305	0
0.0037	0.6569	0.5
0.0384	0.5324	0
0.0028	0.5312	0.5312
0.046	0.436	0.4089
0.0038	0.4305	0
0.0709	0.4265	0.1135
0.047	0.5576	0
0.0427	0.4794	0
0.031	0.4687	0
0.0083	0.4515	1
0.0164	0.4305	0
0.0099	0.4269	0
0.0146	0.3564	0
0.0102	0.4305	0
0.0189	0.4471	0
0.0225	0.4517	0
0.0723	0.3495	0
0.0345	0.3716	0.4806
0.0467	0.4305	0
0.0354	0.4516	0
0.1083	0.5673	0
0.0103	0.4305	0
0.0996	0.628	0.6274
0.0046	0.4501	0
0.0145	0.3194	0.3194
0.0143	0.4305	0
0.0183	0.6032	0
0.0034	1	0.5
0.0776	0.6056	0
0.0063	0.4305	0.3314
0.0038	0.4305	0
0.0152	0.3607	0
0.0067	1	1
0.0131	0.4305	0
0.0074	0.4119	0.5
0.0131	0.4305	0
0.0226	0.3484	0
0.0363	0.4305	0
0.0038	0.4305	0
0.0038	0.4305	0
0.0109	0.2588	0.3099
0.0055	0.4509	0
0.0031	0.4305	0
0.0608	0.436	0
0.0277	0.4341	0.3587
0.0043	0.4875	1
0.0442	0.442	0
0.0264	0.4872	0.4826
0.0105	0.4305	0
0.0124	0.5754	0
0.0829	0.3336	0
0.0909	0.5688	0
0.0209	0.4416	0
0.0134	0.2834	0
0.0137	0.4269	0
0.00501034	0.412178	0
0.0064	0.4305	0
0.0161	0.305	0.6441
0.0084	0.3968	0
0.0466	0.436	0
0.0537	0.4407	0
0.0031	0.4243	0.4163
0.0207	0.436	0
0.0132	0.4269	0
0.0244	0.4862	0.6532
0.0291	0.4305	0
0.0099	0.4407	0
0.0219	0.4269	0
0.0183	0.4863	0
0.0086	0.4451	1
0.0017	0.3358	0.5019
0.0239	0.3334	1
0.0137	0.4269	0
0.0031	0.4305	0
0.013	0.4269	0
0.0238	0.2871	0
0.0862	0.5839	0
0.0035	0.4305	0
0.005	0.4509	0
0.0403	0.4711	0
0.00501034	0.412178	0
0.0128	0.4305	0
0.0145	0.3194	0.3194
0.0739	0.5652	0
0.0038	0.4382	0.4006
0.0789	0.369	0
0.0604	0.4305	0
0.0132	0.4305	0
0.0038	0.4243	0.1415
0.0702	0.5649	0
0.0017	0.5273	0.2278
0.0102	0.5736	0
0.0038	0.3934	0.3934
0.035	0.3571	0.5
0.0038	0.4305	0
0.0116	0.4324	0
0.0651	0.6398	0.626
0.023	0.3406	0
0.0585	0.3593	0
0.0078	0.2729	0
0.017	0.4305	0.026
0.0636	0.5646	0
0.0214	0.4407	0
0.0132	0.4243	0
0.0134	0.4305	0
0.0607	0.6396	0.6384
0.0101	0.5736	0
0.0137	0.4269	0
0.0231	0.5576	0
0.0471	0.5576	0
0.0038	0.4305	0
0.0137	0.4269	0
0.0442	0.442	0
0.0094	0.436	0
0.0771	0.5655	0
0.0097	0.436	0.3782
0.0195	0.4305	0
0.034	0.3203	0
0.0509	0.4743	0.4689
0.0086	0.4451	1
0.0162	0.6249	0.6162
0.0435	0.4305	0
0.0293	0.3322	0.3122
0.0158	1	0.5
0.0098	0.4305	0
0.0822	0.566	0
0.0342	0.4324	0
0.0217	0.5662	0
0.0228	0.436	0
0.0034	0.4305	0
0.0741	0.5678	0
0.0134	0.5576	0
0.0042	0.4851	0
0.0102	0.436	0
0.0618	0.4305	0
0.0204	0.4243	0
0.0217	0.2632	0.9228
0.0389	0.436	0
0.038	0.4656	0.4656
0.0356	0.4305	0
0.0251	0.2561	0.2515
0.0433	0.5634	0
0.0524	0.4507	0.382
0.0032	0.4305	0
0.0171	0.4732	0.0256
0.0832	0.5295	0.6362
0.0877	0.5661	0
0.0217	0.2531	0.9224
0.0347	0.5576	0
0.0148	0.4187	0.9254
0.0058	0.4305	0
0.0302	0.4634	0
0.0055	0.4509	0
0.0117	0.3838	0
0.0337	0.4305	0
0.0805	0.3259	0.6473
0.0137	0.4269	0
0.0168	0.436	0
0.0212	1	1
0.0145	1	0.5
0.0347	0.5576	0
0.0496	0.4913	0.4907
0.0512	0.5476	0.6655
0.0067	0.4163	0
0.0240712	0.552438	0
0.0133	0.4305	0
0.0071	0.2987	0.2987
0.0038	0.4305	0
0.0756	0.2599	0.3326
0.0081	0.2773	0
0.0038	0.4305	0
0.0038	0.4305	0
0.0266	0.4589	0
0.0217	1	0.5
0.0031	0.4305	0
0.0243	0.436	0
0.0533	0.4305	0
0.047	0.4305	0
0.0187	0.6368	0
0.0115	0.2854	0.5701
0.0304	0.3525	0
0.007	0.5273	0
0.0353	0.4514	0
0.0017	0.4817	0.3204
0.012	0.9883	0.5
0.0262	0.4305	0
0.0034	0.4305	0
0.0322	0.4305	0
0.0233	0.2831	0.6509
0.0055	0.4509	0
0.0359	0.4573	0
0.0137	0.3708	0
0.0063	0.3596	0.2871
0.0259241	0.553904	0.549622
0.0598	0.4018	0.3974
0.0326	0.443	0.443
0.0472	0.4865	0.4826
0.013	0.3638	0
0.0017	0.5736	0.4135
0.0038	0.4305	0
0.0032	0.4305	0
0.0218	0.6131	0.639
0.0038	0.4305	0
0.0269	0.3183	0.4675
0.0104	0.2543	0.2875
0.0068	1	0.5
0.0223	0.5502	0
0.0355	0.3324	0.3296
0.0094	0.4305	0
0.0273	0.3321	0
0.0269	0.4305	0
0.0434	0.5602	0
0.0032	0.4305	0
0.0684	0.6256	0.6183
0.0038	0.4305	0
0.0743	0.5651	0
0.1102	0.4018	0
0.0226	0.339	0
0.022	0.3105	0.6539
0.0137	0.5006	0
0.0065	0.4407	0
0.0181	0.9367	1
0.0017	0.5576	0
0.0643	0.5641	0
0.0409	0.4248	0.6446
0.035	0.4305	0
0.0071	1	1
0.0068	0.9052	0.5
0.0535	0.5628	0
0.0441	0.5075	0
0.0441	0.5075	0
0.0081	0.4429	0
0.0135	0.4305	0
0.0038	0.4305	0
0.0925	0.5665	0
0.021	0.4324	0.3461
0.0043	0.5576	0.1835
0.0259	0.4269	0
0.0304	0.3934	0
0.0034	0.427	0.5
0.0437	0.2833	0.2718
0.0261	0.4305	0
0.0197	0.4305	0
0.088	0.6293	0.6278
0.0088	0.5736	0
0.0141	1	0.5
0.046	0.4844	0.483
0.0034	0.4291	0.5
0.0512	0.5476	0.6655
0.0536	0.4875	0.4826
0.0153	0.4305	0
0.0866	0.6199	0.6199
0.0135	0.3927	0.3927
0.0166	0.444	0
0.008	0.2729	0
0.0095	0.4305	0
0.0289	0.5754	0
0.0709	0.4265	0.1135
0.4363	0.2877	0.4402
0.0014	0.4606	0
0.0038	0.4305	0
0.0071	0.4305	0
0.1052	0.6067	0
0.0343	0.334	1
0.0612	0.3559	0.326
0.0069	0.4305	0
0.0374	0.4305	0
0.0115	0.4269	0
0.0038	0.4305	0.2121
0.0653	0.4383	0
0.02	0.4305	0.1759
0.0211	0.5014	0.4095
0.0102	0.4305	0
0.0187	0.6177	0
0.0262	0.4324	0
0.0038	0.2679	0
0.4003	0.4413	0.4412
0.0038	0.4305	0
0.0135	0.4269	0
0.0136	0.3675	0
0.0073	0.3194	0.4031
0.0146	0.5736	0
0.0925	0.5665	0
0.0227	0.4305	0
0.0208	0.4305	0.2521
0.0198	0.7391	0.735
0.0137	0.4269	0
0.007	1	0.5
0.0042	0.4851	0
0.0314	0.2865	0.4658
0.1009	0.5673	0
0.0038	0.4305	0
0.0464	0.5615	0
0.0356	0.2598	0.5771
0.0906	0.4282	0.6461
0.0096	0.4243	0
0.0122	0.4269	0
0.0111	0.7595	1
0.0031	0.4243	0.3013
0.0109407	0.294505	0.464146
0.0149	0.5101	0.5064
0.0233	0.4305	0
0.0035	0.4305	0
0.0832	0.5295	0.6362
0.0408	0.4305	0
0.0103	0.4509	0
0.0822	0.566	0
0.0634	0.5639	0
0.0469	0.4878	0.4826
0.0159	0.4112	0
0.0214	0.4416	0
0.0356	0.4305	0
0.0046	0.4509	0
0.0116	0.4324	0
0.0518	0.2515	0.2443
0.0038	0.4039	1
0.0249	0.9786	1
0.0109	0.5754	0
0.0496	0.4826	0.4826
0.013	0.4269	0
0.0038	0.4305	0
0.0118	0.2815	0
0.0131	0.4419	0.4147
0.038	0.4243	0.3385
0.0046	0.4509	0
0.0815	0.5656	0
0.0415	0.5634	0
0.0036	0.4305	0
0.0133	0.436	0
0.0245	0.5321	0.47
0.0889	0.5663	0
0.0017	0.5273	0
0.0552	0.4305	0
0.0128	0.3822	0.4857
0.0061	0.2632	0.239
0.0061	0.5576	0
0.0259	0.4775	0.4727
0.0043	0.4875	1
0.0142	0.5665	0.5591
0.0038	0.4305	0
0.0017	0.3384	0
0.0032	0.4305	0
0.0936	0.5696	0
0.014	0.4305	0
0.0152	0.5898	0
0.0032	0.4305	0
0.0128	0.3822	0.4857
0.0106	0.4324	0.3869
0.0201	0.5034	0
0.0033	0.4305	0
0.00745154	0.412178	0
0.0287	0.2856	0.485
0.039	0.4573	0
0.0759	0.3512	0.6451
0.0499	0.4728	0.4699
0.0805	0.4106	0
0.0143	0.591	0.5861
0.0132	0.3653	0
0.003	0.4305	0
0.0031	0.4305	0
0.0045	0.5576	0
0.0137	0.3708	0
0.0861	0.3762	0
0.0096	0.979	0.5
0.0133	0.2834	0
0.0034	0.4305	0
0.0265	0.3806	0.6733
0.0137	0.4383	0.4237
0.0033	0.4305	0
0.0906	0.4282	0.6461
0.0228	0.333	0
0.0396	0.4305	0
0.0335759	0.422421	0.417507
0.0259	0.4775	0.4727
0.0246	0.2961	0.6494
0.024	0.2895	0
0.0085	0.3513	0.5271
0.0287	0.4305	0
0.016	0.5736	0
0.0047	0.4509	0.4329
0.0237	0.4305	0
0.0146	0.4712	0.5929
0.0389	0.436	0
0.0237	0.5736	0
0.0754	0.5651	0
0.0709	0.4265	0.1135
0.0154	0.5023	0.4737
0.0171	0.4732	0.0256
0.007	0.4305	0.31
0.0131	0.3675	0
0.005	0.4509	0
0.0066	0.5273	0
0.0265	0.3806	0.6733
0.047	0.3887	0
0.0071	0.4305	0
0.0134	0.3653	0
0.0256	0.4305	0
0.0381	0.4305	0
0.0261	0.4324	0
0.0268223	0.548194	0.544124
0.0096	0.4305	0
0.0142	0.8807	0
0.0243	0.4537	0.4189
0.0145	0.3194	0.3194
0.0034	0.3589	0.5
0.0065	0.4305	0
0.0237	0.5736	0
0.0038	0.4305	0
0.0215	0.5576	0
0.0293	0.3322	0.3122
0.051	0.5576	0
0.0304	0.436	0
0.0909	0.5688	0
0.0187	0.6368	0
0.0046	0.3659	0.2239
0.0576	0.4114	0
0.0219	0.4331	0.4162
0.0378	0.4305	0
0.0033	0.4305	0
0.0175	0.3976	0.4757
0.1017	0.6503	0.6503
0.005	0.4509	0
0.0177	1	0.5
0.0433	0.4305	0
0.0394	0.37	0
0.0355	0.2852	0
0.0171	0.3077	0.3077
0.0829	0.3336	0
0.0268	0.5586	0
0.0236	0.3205	0
0.0166	0.5576	0
0.0181	0.4695	0.746
0.0141	0.3563	0
0.0137	0.4269	0.3644
0.0034	0.6605	1
0.00257299	0.412178	0
0.0038	0.4305	0
0.0149	0.5101	0.5064
0.0045	0.4509	0
0.002	0.427	0.5
0.0137736	0.387067	0.601201
0.00268228	0.412178	0
0.0211	0.4942	0
0.0107	1	0.5
0.0214	0.3223	0
0.0192	0.5034	0.6326
0.024	0.2895	0
0.0063	0.5921	0.456
0.0031	0.4305	0
0.019	0.436	0
0.0805	0.3263	0.6473
0.0725	0.3886	0.3886
0.0503	0.4305	0
0.01	0.4305	0
0.0084	0.355	0
0.0249	0.4415	0
0.0435	0.4305	0
0.0092	0.4539	0
0.0751	0.5656	0
0.0812	0.5662	0
0.0078	0.9798	0.5
0.0305	0.3629	0.4708
0.0401	0.4403	0.4403
0.0293	0.3322	0.3122
0.0052	0.4509	0
0.0032	0.4305	0
0.0258	0.436	0
0.0052	0.4509	0
0.0042	1	0.5
0.0128	0.3822	0.4857
0.0033	0.9607	0.5
0.0038	0.4305	0
0.0046	0.9565	0.5
0.0391	0.4371	1
0.0709	0.4265	0.1135
0.0133	0.4305	0
0.0425	0.4835	0.4826
0.0374	0.4305	0
0.0109	0.4305	0
0.00516351	0.411374	0
0.0702	0.2991	0
0.0208	0.4305	0
0.0234	0.4269	0
0.0816	0.6052	0
0.008	0.2679	0
0.0182	0.4361	0.2825
0.0542	0.6548	0.6548
0.0137	0.3708	0
0.0759	0.3512	0.6451
0.0275	0.3264	0.4682
0.0202	0.5736	0
0.0115	0.4305	0
0.0694	0.5856	0
0.0291	0.4305	0
0.0206	0.5736	0
0.0191	0.4418	0.4219
0.0096	0.979	0.5
0.0137	0.4269	0
0.0204	0.3411	0.3848
0.0084	0.436	0
0.4525	0.3086	0.4297
0.0038	0.4305	0
0.0103	0.4509	0
0.1041	0.2628	0.652
0.0094	0.436	0
0.0137736	0.387067	0.601201
0.0223	0.4305	0
0.1192	0.7574	0.7473
0.0512	0.5476	0.6655
0.0137	0.4269	0
0.0036	0.436	0
0.0062	0.436	0
0.0213	0.5284	0.6365
0.0112	0.4269	0
0.0038	0.4305	0
0.0685	0.5645	0
0.0135	0.3598	0
0.0065	0.4305	0
0.0607	0.6396	0.6384
0.0038	0.4305	0
0.0017	0.3736	0
0.0398	0.6095	0
0.0038	0.4305	0
0.0725	0.3886	0.3886
0.0235	0.4269	0
0.0258	0.4305	0
0.0848	0.356	0
0.0263	0.4013	0
0.0038	0.427	0.5
0.0068	0.4305	0
0.0133	0.2834	0
0.0038	0.427	0.5
0.0162	0.6249	0.6162
0.0729	0.3405	0
0.0134	0.4207	0.417
0.048	0.306	0
0.0488	0.436	0
0.0146	0.5898	0
0.0493	0.5576	0
0.0585	0.3593	0
0.0085	0.2773	0
0.0062	0.5576	0
0.0017	0.5576	0
0.0125	0.4383	0
0.0906	0.4282	0.6461
0.0314658	0.412178	0
0.0017	0.5576	0
0.0038	0.4305	0
0.0374	0.5616	0.0381
0.0396	0.4517	0
0.0135	0.3927	0.3927
0.0059	0.4305	0
0.0217	0.4269	0
0.0032	0.4305	0
0.052	0.4949	0.4949
0.0205	0.2558	1
0.0066	0.2851	0
0.0222	0.4416	0
0.0115	0.4269	0
0.0805	0.3259	0.6473
0.0364	0.283	0
0.0036	0.4305	0
0.0038	0.4305	0
0.0365	0.4123	1
0.0135	0.4305	0
0.0095	0.4305	0
0.0217	1	0.5
0.0161	0.5898	0
0.0051	0.4509	0
0.0114	0.4269	0
0.0038	0.4305	0
0.0486	0.6383	0.6365
0.0538	0.5576	0
0.0055	0.4509	0
0.006	0.5461	0
0.0273	0.3321	0
0.0405	0.4305	0
0.0046	0.3659	0.2239
0.0066	0.436	0.268
0.0038	0.4243	0.3635
0.0368	0.4305	0
0.0161	0.305	0.6441
0.0323	0.3385	0.6408
0.0993	0.6064	0
0.0038	0.4243	0.404
0.0137	0.2834	0
0.0218	0.2618	0.9191
0.011	0.5878	0
0.0068	0.4243	0
0.0137	0.4269	0
0.0064	0.4305	0
0.0281	0.6365	0.6365
0.0128	0.3822	0.4857
0.0186	0.7473	0
0.0045	0.4539	0
0.0217	0.4269	0
0.0069	0.4305	0.4028
0.0259241	0.553904	0.549622
0.0434	0.4305	0
0.0017	0.5576	0
0.00751118	0.412178	0
0.0105	0.5576	0
0.0038	0.3873	0.3201
0.0221	0.2653	0.9366
0.0435	0.4305	0
0.0038	0.4305	0
0.0906	0.4282	0.6461
0.0731	0.5652	0
0.0031	0.427	0.5
0.0162	0.4305	0
0.0369	0.2516	0.2299
0.0038	0.4305	0
0.0226777	0.38996	0
0.0047	0.4451	0
0.0049	0.4509	0
0.0622	0.3861	0
0.0103	0.4305	0
0.0598	0.4018	0.3974
0.0346	0.558	0
0.014	0.3636	0
0.0169	0.4593	0.4416
0.0674	0.4305	0
0.0046	0.9565	0.5
0.0016	0.427	0.5
0.0635	0.4305	0
0.0038	0.4305	0
0.0209	0.3879	0.5
0.0231	0.3927	0.392
0.0034	0.4305	0
0.036	0.64	0
0.0233	0.4305	0
0.0206	0.5736	0
0.0171	0.5315	0
0.0267	0.3135	0.4671
0.0179	0.5852	0
0.0091	0.9818	0.5
0.0049	0.3517	0
0.0064	0.4305	0
0.0136	0.4269	0
0.0143	0.3659	0
0.0355	0.343	0
0.0131	0.4419	0.4147
0.0406	0.4305	0
0.0304	0.3525	0
0.0576	0.4114	0
0.0541	0.5273	0
0.0224	0.4419	0.0794
0.0775	0.5656	0
0.0239	0.9798	0.5
0.0137	0.4324	0.4078
0.0127	0.373	0
0.0204	0.436	0
0.0064	0.4305	0
0.0114	0.4269	0
0.0405	0.4419	0.4285
0.0226	0.4416	0
0.0032	0.4305	0
0.0442	0.442	0
0.0137736	0.387067	0.601201
0.0979	0.3989	0.5763
0.0204	0.4419	0
0.0048	1	1
0.014	0.3636	0
0.0137	0.4269	0
0.0137	0.2861	0.4766
0.0725	0.5685	0
0.0133	0.3675	0
0.0114	0.4207	0
0.0778	0.469	0
0.0834	0.5664	0
0.0415	0.4751	0.4644
0.0815	0.3753	0
0.0283	1	0.5
0.0601	0.5635	0
0.0219	0.6131	0
0.0464	0.3234	0
0.0574	0.4874	0.4826
0.0245	0.5321	0.47
0.0624	0.3576	0
0.0038	0.4305	0
0.0431	0.5601	0
0.0038	0.4305	0
0.044	0.436	0
0.0031	0.4305	0
0.0112	0.5736	0
0.0038	0.4305	0
0.0167	0.436	0
0.0068	0.4305	0
0.0101	0.4305	0
0.0128	0.4305	0
0.0139	0.516	0
0.0234	0.4269	0
0.011	0.2607	0.4247
0.038	0.4656	0.4656
0.006	0.4305	0
0.0677	0.5649	0
0.022	0.4461	0
0.0138	0.4305	0
0.0227	0.4305	0
0.0038	0.4305	0
0.0038	0.4243	0.3314
0.0621	0.4909	0.6594
0.0092	0.2729	0
0.041	0.4305	0
0.0133	0.4269	0
0.0193	0.4772	0.476
0.0235	0.4243	0
0.0481	0.5736	0
0.0137736	0.387067	0.601201
0.0655	0.4119	0
0.0499	0.4728	0.4699
0.004	0.2803	0
0.0261	0.2592	0
0.0971	0.5667	0
0.0963	0.6003	0
0.0135	0.3107	0.2408
0.0137	0.4269	0
0.0066	1	0.5
0.0397	0.4305	0
0.0021	0.4023	0
0.017	0.5576	0
0.0186	0.4295	0
0.0768	0.5781	0.5626
0.1041	0.2628	0.652
0.0136	0.4269	0
0.0038	0.4305	0
0.0017	0.3153	0
0.0709	0.4265	0.1135
0.082	0.3694	0
0.0133	0.4305	0
0.0598	0.4018	0.3974
0.0156492	0.412178	0.389542
0.0038	0.4305	0
0.0151	0.3313	0.7768
0.0086	0.4451	1
0.0137	0.2825	0
0.0038	0.4305	0
0.0202	0.4305	0
0.0032	0.4305	0
0.0128	0.3654	0
0.0055	0.4509	0
0.0343	0.334	1
0.0034	0.5736	0.5578
0.0121	0.5736	0
0.0187	1	0.5
0.0063	0.2987	0
0.0234	0.4624	0.4789
0.0113	0.3532	0
0.1313	0.6195	0
0.0643	0.5642	0
0.0516	0.3667	0.489
0.0051	0.5024	0.3453
0.0179	0.4273	0
0.012	0.9729	0.5
0.0038	0.4305	0
0.0558	0.4892	0.4854
0.0031	0.4243	0.0459
0.0102	0.4305	0
0.0217	0.4269	0
0.0121	0.6131	0
0.0518	0.2515	0.2443
0.0186	0.7473	0
0.0038	0.4243	0.2375
0.0038	0.4305	0
0.0125	0.3064	0.3594
0.0185	0.4418	0
0.0506	0.5625	0
0.0113	0.4207	0.4076
0.0038	0.281	0.2184
0.0148	0.4187	0.9254
0.0862	0.5839	0
0.0222	0.4407	0
0.0055	0.4509	0
0.0138	0.2834	0
0.0031	0.4305	0
0.0141	0.6434	0
0.0225	0.5576	0
0.028	0.3641	0.4884
0.0046	0.2532	0.2178
0.0558	0.4067	0.4897
0.0038	0.4305	0
0.0335759	0.422421	0.417507
0.0059	0.2519	0
0.0236	0.5576	0
0.0191	0.436	0
0.0038	0.4305	0
0.039	0.4573	0
0.0031	0.4305	0
0.0048	0.4509	0
0.0137	0.3663	0
0.0609	0.4305	0
0.0064	0.4243	0.0519
0.0445	0.4305	0
0.0773	0.4087	0
0.0017	0.5576	0
0.0132	0.4305	0
0.0115	0.4269	0
0.01	0.4305	0
0.0759	0.3512	0.6451
0.0805	0.3259	0.6473
0.0699	0.565	0
0.0512	0.5476	0.6655
0.0725	0.5685	0
0.0499	0.4317	0.407
0.0137	0.4371	0.436
0.0325	0.6196	0.6196
0.0106	1	0.5
0.0138	0.3143	0.4694
0.0268	0.4407	0
0.0576	0.4114	0
0.0574	0.4859	0.4826
0.0134	0.4305	0
0.0036	0.4305	0
0.0038	0.4291	0.3394
0.0401	0.4403	0.4403
0.0038	0.4305	0
0.0469	0.4305	0
0.0323	0.3385	0.6408
0.00245038	0.412178	0
0.0487	0.3488	0
0.0244	0.5576	0
0.0102	0.2599	0
0.0137	0.4269	0
0.0134	0.4269	0
0.0592	0.3057	0
0.0433	0.5634	0
0.0323	0.3385	0.6408
0.0512	0.5476	0.6655
0.0134	0.4305	0
0.0384	0.5324	0
0.0038	0.4305	0
0.0078	0.3522	0
0.0125	0.4324	0
0.0629	0.4407	0
0.0046	0.4539	0
0.0773	0.5661	0
0.0264	0.5736	0
0.0131	0.9883	0.5
0.0131	0.4419	0.4147
0.0146	0.4305	0

Assayability

Assay information

No assay information for this target.

Reagent availability

No reagent availability information for this target.

Bibliographic References

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Gene identifier	OVOC9796 (Onchocerca volvulus),

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