Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.
717 records found | Showing page 1 of 29 (records 1-25) | Number of records to display | Find orthologs in
Organism | Name | Ortholog group | Product |
---|---|---|---|
T. cruzi | TcCLB.407477.30 | OG5_127443 | diphthine synthase, putative |
T. cruzi | TcCLB.410589.10 | OG5_126856 | AMP deaminase, putative |
T. cruzi | TcCLB.419703.20 | OG5_128387 | ubiquitin carboxyl-terminal hydrolase, putative |
T. cruzi | TcCLB.420989.10 | OG5_141696 | protein phosphatase 2C, putative |
T. cruzi | TcCLB.422189.10 | No group | nucleoside phosphatase, putative |
T. cruzi | TcCLB.427247.10 | OG5_153856 | CMGC/DYRK protein kinase, putative |
T. cruzi | TcCLB.427789.30 | OG5_127076 | NAD+ synthase, putative |
T. cruzi | TcCLB.438059.10 | OG5_129030 | serine/threonine-protein phosphatase PP1 alpha |
T. cruzi | TcCLB.447255.20 | OG5_127825 | Silent information regulator 2 related protein 3 |
T. cruzi | TcCLB.453445.20 | OG5_127739 | ubiquitin-conjugating enzyme E2, putative |
T. cruzi | TcCLB.460127.20 | OG5_127953 | metallo- peptidase, Clan M- Family M48 |
T. cruzi | TcCLB.463451.10 | OG5_135887 | NEK family Serine/threonine-protein kinase, putative |
T. cruzi | TcCLB.467287.30 | OG5_180610 | ATPase beta subunit, putative |
T. cruzi | TcCLB.473111.10 | OG5_129040 | lathosterol oxidase, putative |
T. cruzi | TcCLB.484299.10 | No group | trypanothione reductase, putative |
T. cruzi | TcCLB.503405.10 | OG5_127569 | glutamine synthetase, putative |
T. cruzi | TcCLB.503477.20 | OG5_127238 | transaldolase, putative |
T. cruzi | TcCLB.503479.30 | OG5_126762 | adenylate kinase 1 |
T. cruzi | TcCLB.503513.10 | OG5_143898 | casein kinase II, alpha chain, putative |
T. cruzi | TcCLB.503521.50 | OG5_128034 | UTP-glucose-1-phosphate uridylyltransferase 2, putative |
T. cruzi | TcCLB.503555.30 | OG5_126785 | trypanothione reductase, putative |
T. cruzi | TcCLB.503579.110 | OG5_146749 | pseudouridylate synthase I, putative |
T. cruzi | TcCLB.503581.20 | OG5_148443 | peptidyl-prolyl cis-trans isomerase, putative |
T. cruzi | TcCLB.503583.80 | OG5_139926 | dual specificity protein phosphatase or MAP kinase phosphatase, putative |
T. cruzi | TcCLB.503589.10 | OG5_127109 | GDP-mannose pyrophosphorylase |