Detailed information for compound 1005254

Basic information

Technical information
  • TDR Targets ID: 1005254
  • Name: (4aR,5R,6aR,6aS,6bR,8aR,10S,12aR,14bR)-5,10-d iacetyloxy-2,2,6a,6b,9,9,12a-heptamethyl-1,3, 4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydr opicene-4a-carboxylic acid
  • MW: 556.773 | Formula: C34H52O6
  • H donors: 1 H acceptors: 4 LogP: 7.48 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 2
  • SMILES: CC(=O)O[C@H]1CC[C@]2([C@H](C1(C)C)CC[C@@]1([C@@H]2CC=C2[C@@]1(C)C[C@H]([C@@]1([C@@H]2CC(C)(C)CC1)C(=O)O)OC(=O)C)C)C
  • InChi: 1S/C34H52O6/c1-20(35)39-26-13-14-31(7)24(30(26,5)6)12-15-32(8)25(31)11-10-22-23-18-29(3,4)16-17-34(23,28(37)38)27(40-21(2)36)19-33(22,32)9/h10,23-27H,11-19H2,1-9H3,(H,37,38)/t23-,24+,25-,26+,27-,31+,32-,33-,34-/m1/s1
  • InChiKey: ZVUFWBWAZNPNAT-LMUYBSRQSA-N  


Substructure search Similarity search

Network

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Synonyms

  • (4aR,5R,6aR,6aS,6bR,8aR,10S,12aR,14bR)-5,10-diacetoxy-2,2,6a,6b,9,9,12a-heptamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylic acid

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Protein kinase domain containing protein 0.0416 1 1
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0416 1 1
Entamoeba histolytica tyrosine kinase, putative 0.0416 1 0.5
Echinococcus granulosus tyrosine protein kinase Fyn 0.0416 1 1
Entamoeba histolytica protein kinase, putative 0.0416 1 0.5
Schistosoma mansoni tyrosine kinase 0.0416 1 1
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0416 1 0.5
Entamoeba histolytica protein kinase, putative 0.0416 1 0.5
Brugia malayi Protein kinase domain containing protein 0.0416 1 1
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0056 0.0901 0.0805
Loa Loa (eye worm) TK/EGFR protein kinase 0.0416 1 1
Loa Loa (eye worm) hypothetical protein 0.0046 0.0664 0.0664
Schistosoma mansoni tyrosine kinase 0.0416 1 1
Brugia malayi Protein kinase domain containing protein 0.0416 1 1
Loa Loa (eye worm) mbt repeat family protein 0.0046 0.0664 0.0664
Loa Loa (eye worm) RGC/RGC protein kinase 0.0416 1 1
Onchocerca volvulus 0.0048 0.07 0.0038
Schistosoma mansoni tyrosine kinase 0.0416 1 1
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0044 0.0616 0.0572
Brugia malayi Protein kinase domain containing protein 0.0416 1 1
Brugia malayi protein-tyrosine kinase 0.0416 1 1
Schistosoma mansoni sex comb on midleg homolog 0.0046 0.0664 0.0664
Entamoeba histolytica tyrosine kinase, putative 0.0416 1 0.5
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0416 1 0.5
Loa Loa (eye worm) TK/KIN6 protein kinase 0.0416 1 1
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0416 1 1
Schistosoma mansoni protein kinase 0.0416 1 1
Schistosoma mansoni hypothetical protein 0.0184 0.4134 0.4134
Loa Loa (eye worm) protein kinase domain-containing protein 0.0416 1 1
Echinococcus granulosus SAM and MBT domain containing protein 0.0046 0.0664 0.062
Schistosoma mansoni tyrosine kinase 0.0416 1 1
Entamoeba histolytica protein kinase domain containing protein 0.0416 1 0.5
Schistosoma mansoni glutaminase 0.0296 0.698 0.698
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0044 0.0616 0.0572
Echinococcus multilocularis receptor type guanylyl cyclase 0.0416 1 1
Schistosoma mansoni bromodomain containing protein 0.0061 0.1046 0.1046
Onchocerca volvulus 0.0416 1 1
Echinococcus multilocularis polycomb protein SCMH1 0.0046 0.0664 0.062
Onchocerca volvulus 0.0416 1 1
Loa Loa (eye worm) hypothetical protein 0.0037 0.0435 0.0435
Echinococcus multilocularis survival motor neuron protein 1 0.0234 0.5405 0.5384
Trichomonas vaginalis TKL family protein kinase 0.0416 1 1
Toxoplasma gondii protein kinase 0.0416 1 1
Echinococcus multilocularis histone acetyltransferase MYST2 0.0053 0.0826 0.0783
Schistosoma mansoni serine/threonine RGC 0.0416 1 1
Trichomonas vaginalis TKL family protein kinase 0.0416 1 1
Entamoeba histolytica protein kinase domain containing protein 0.0416 1 0.5
Trichomonas vaginalis TKL family protein kinase 0.0416 1 1
Brugia malayi integrin-linked kinase 0.0416 1 1
Entamoeba histolytica protein kinase domain containing protein 0.0416 1 0.5
Trichomonas vaginalis TKL family protein kinase 0.0416 1 1
Echinococcus granulosus c src tyrosine kinase 0.0416 1 1
Echinococcus granulosus tyrosine kinase 0.0416 1 1
Loa Loa (eye worm) TK/FER protein kinase 0.0416 1 1
Onchocerca volvulus 0.0416 1 1
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0416 1 1
Loa Loa (eye worm) TK/RYK protein kinase 0.0416 1 1
Loa Loa (eye worm) hypothetical protein 0.0234 0.5405 0.5405
Echinococcus granulosus tyrosine protein kinase Blk 0.0416 1 1
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0416 1 1
Echinococcus granulosus polycomb protein SCMH1 0.0046 0.0664 0.062
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.0616 0.0616
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0416 1 1
Brugia malayi ephrin receptor 1 precursor 0.0416 1 1
Giardia lamblia Protein 21.1 0.0416 1 0.5
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0416 1 0.5
Echinococcus granulosus retinal guanylyl cyclase 2 0.0416 1 1
Echinococcus granulosus tyrosine protein kinase HCK 0.0416 1 1
Schistosoma mansoni protein kinase 0.0416 1 1
Echinococcus multilocularis protein kinase 0.0416 1 1
Trichomonas vaginalis TKL family protein kinase 0.0416 1 1
Trichomonas vaginalis TKL family protein kinase 0.0416 1 1
Schistosoma mansoni hypothetical protein 0.0416 1 1
Schistosoma mansoni protein kinase 0.0416 1 1
Entamoeba histolytica ankyrin repeat protein 0.0416 1 0.5
Schistosoma mansoni tyrosine kinase 0.0416 1 1
Entamoeba histolytica hypothetical protein 0.0416 1 0.5
Loa Loa (eye worm) TK/ALK protein kinase 0.0416 1 1
Entamoeba histolytica protein kinase, putative 0.0416 1 0.5
Onchocerca volvulus Tyrosine kinase receptor Cad96Ca homolog 0.0416 1 1
Entamoeba histolytica serine/threonine kinase, putative 0.0416 1 0.5
Entamoeba histolytica protein kinase, putative 0.0416 1 0.5
Entamoeba histolytica tyrosine kinase, putative 0.0416 1 0.5
Loa Loa (eye worm) hypothetical protein 0.0416 1 1
Entamoeba histolytica hypothetical protein 0.0416 1 0.5
Entamoeba histolytica hypothetical protein 0.0416 1 0.5
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0416 1 1
Onchocerca volvulus 0.0416 1 1
Echinococcus granulosus tyrosine protein kinase pr2 0.0416 1 1
Plasmodium falciparum tyrosine kinase-like protein 0.0416 1 1
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0416 1 1
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0416 1 0.5
Echinococcus multilocularis protein tyrosine kinase 0.0416 1 1
Onchocerca volvulus 0.0416 1 1
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0416 1 0.5
Schistosoma mansoni tyrosine kinase 0.0416 1 1
Echinococcus multilocularis epidermal growth factor receptor 0.0416 1 1
Echinococcus multilocularis tyrosine protein kinase Srms 0.0416 1 1
Loa Loa (eye worm) glutaminase 0.0296 0.698 0.698
Echinococcus multilocularis activated cdc42 kinase 1 0.0416 1 1
Schistosoma mansoni tyrosine kinase 0.0416 1 1
Brugia malayi Protein kinase domain containing protein 0.0416 1 1
Brugia malayi mbt repeat family protein 0.0046 0.0664 0.0565
Schistosoma mansoni hypothetical protein 0.0184 0.4134 0.4134
Brugia malayi Protein kinase domain containing protein 0.0416 1 1
Brugia malayi Receptor family ligand binding region containing protein 0.0416 1 1
Trichomonas vaginalis AGC family protein kinase 0.0416 1 1
Schistosoma mansoni myelin transcription factor 1 myt1 0.0053 0.0826 0.0826
Brugia malayi Raf kinase 0.0416 1 1
Echinococcus granulosus fibroblast growth factor receptor 4 0.0416 1 1
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0416 1 1
Entamoeba histolytica tyrosine kinase, putative 0.0416 1 0.5
Schistosoma mansoni serine/threonine protein kinase 0.0416 1 1
Trichomonas vaginalis TKL family protein kinase 0.0416 1 1
Schistosoma mansoni serine/threonine protein kinase 0.0416 1 1
Loa Loa (eye worm) RGC/RGC protein kinase 0.0416 1 1
Loa Loa (eye worm) hypothetical protein 0.0416 1 1
Entamoeba histolytica hypothetical protein 0.0416 1 0.5
Loa Loa (eye worm) TK/FER protein kinase 0.0416 1 1
Entamoeba histolytica tyrosine kinase, putative 0.0416 1 0.5
Trichomonas vaginalis conserved hypothetical protein 0.0416 1 1
Echinococcus granulosus epidermal growth factor receptor 0.0416 1 1
Trichomonas vaginalis TKL family protein kinase 0.0416 1 1
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0048 0.07 0.0601
Trichomonas vaginalis conserved hypothetical protein 0.0416 1 1
Schistosoma mansoni protein kinase 0.0416 1 1
Echinococcus multilocularis kinase suppressor of Ras 1 0.0416 1 1
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0416 1 1
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0056 0.0901 0.0489
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0416 1 1
Echinococcus granulosus tyrosine protein kinase Src64B 0.0416 1 1
Echinococcus granulosus retinal guanylyl cyclase 2 0.0416 1 1
Schistosoma mansoni tyrosine kinase 0.0416 1 1
Echinococcus granulosus FAD linked sulfhydryl oxidase ALR 0.0037 0.0433 0.0388
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.0616 0.0616
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0416 1 1
Echinococcus granulosus tyrosine protein kinase Srms 0.0416 1 1
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0416 1 1
Trichomonas vaginalis TKL family protein kinase 0.0416 1 1
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0416 1 1
Brugia malayi Protein kinase domain containing protein 0.0416 1 1
Brugia malayi Immunoglobulin I-set domain containing protein 0.0416 1 1
Loa Loa (eye worm) TK/FER protein kinase 0.0416 1 1
Echinococcus granulosus tyrosine protein kinase Fyn 0.0416 1 1
Loa Loa (eye worm) hypothetical protein 0.0416 1 1
Brugia malayi Protein kinase domain containing protein 0.0416 1 1
Echinococcus multilocularis c src tyrosine kinase 0.0416 1 1
Brugia malayi Tyrosine-protein kinase abl-1 0.0416 1 1
Schistosoma mansoni tyrosine kinase 0.0416 1 1
Loa Loa (eye worm) TK protein kinase 0.0416 1 1
Trichomonas vaginalis TKL family protein kinase 0.0416 1 1
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.0416 1 1
Entamoeba histolytica hypothetical protein 0.0416 1 0.5
Giardia lamblia Kinase 0.0416 1 0.5
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0056 0.0901 0.0901
Trichomonas vaginalis TKL family protein kinase 0.0416 1 1
Loa Loa (eye worm) TK/FER protein kinase 0.0416 1 1
Onchocerca volvulus 0.0416 1 1
Entamoeba histolytica serine/threonine kinase, putative 0.0416 1 0.5
Trichomonas vaginalis TKL family protein kinase 0.0416 1 1
Trichomonas vaginalis TKL family protein kinase 0.0416 1 1
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0416 1 0.5
Entamoeba histolytica protein kinase domain containing protein 0.0416 1 0.5
Entamoeba histolytica hypothetical protein 0.0416 1 0.5
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0053 0.0826 0.0783
Brugia malayi Tyrosine-protein kinase F09A5.2 in chromosome X, putative 0.0416 1 1
Trichomonas vaginalis TKL family protein kinase 0.0416 1 1
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0416 1 1
Plasmodium falciparum protein kinase, putative 0.0416 1 1
Echinococcus granulosus survival motor neuron protein 1 0.0234 0.5405 0.5384
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0416 1 1
Loa Loa (eye worm) hypothetical protein 0.0416 1 1
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0182 0.4106 0.4078
Trichomonas vaginalis serine-threonine protein kinase, putative 0.0416 1 1
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0416 1 1
Schistosoma mansoni protein kinase 0.0416 1 1
Schistosoma mansoni ephrin receptor 0.0416 1 1
Brugia malayi Protein kinase domain containing protein 0.0416 1 1
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0416 1 1
Entamoeba histolytica protein kinase domain containing protein 0.0416 1 0.5
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0416 1 0.5
Loa Loa (eye worm) TK/INSR protein kinase 0.0416 1 1
Brugia malayi Protein kinase domain containing protein 0.0416 1 1
Trichomonas vaginalis TKL family protein kinase 0.0416 1 1
Trichomonas vaginalis TKL family protein kinase 0.0416 1 1
Entamoeba histolytica tyrosine kinase, putative 0.0416 1 0.5
Loa Loa (eye worm) hypothetical protein 0.004 0.0493 0.0493
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0416 1 1
Echinococcus granulosus tyrosine protein kinase 0.0416 1 1
Entamoeba histolytica protein kinase domain containing protein 0.0416 1 0.5
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0416 1 1
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0416 1 0.5
Loa Loa (eye worm) TK/FER protein kinase 0.0416 1 1
Loa Loa (eye worm) TK/FER protein kinase 0.0416 1 1
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0052 0.0807 0.0807
Loa Loa (eye worm) SRC-1 0.0416 1 1
Entamoeba histolytica hypothetical protein 0.0416 1 0.5
Brugia malayi Furin-like cysteine rich region family protein 0.0416 1 1
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0416 1 1
Loa Loa (eye worm) hypothetical protein 0.0416 1 1
Schistosoma mansoni protein kinase 0.0416 1 1
Loa Loa (eye worm) hypothetical protein 0.0416 1 1
Entamoeba histolytica tyrosine kinase, putative 0.0416 1 0.5
Trichomonas vaginalis TKL family protein kinase 0.0416 1 1
Loa Loa (eye worm) hypothetical protein 0.0416 1 1
Echinococcus multilocularis FAD linked sulfhydryl oxidase ALR 0.0037 0.0433 0.0388
Schistosoma mansoni protein tyrosine kinase 0.0416 1 1
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0044 0.0616 0.0616
Trichomonas vaginalis protein tyrosine kinase, putative 0.0416 1 1
Schistosoma mansoni tyrosine kinase 0.0416 1 1
Schistosoma mansoni tyrosine kinase 0.0416 1 1
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0182 0.4106 0.4078
Loa Loa (eye worm) TK protein kinase 0.0416 1 1
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0416 1 1
Echinococcus multilocularis macrophage colony stimulating factor 1 receptor 0.0416 1 1
Trichomonas vaginalis TKL family protein kinase 0.0416 1 1
Schistosoma mansoni tyrosine kinase 0.0416 1 1
Entamoeba histolytica tyrosine kinase, putative 0.0416 1 0.5
Loa Loa (eye worm) TK/Met protein kinase 0.0416 1 1
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0046 0.0664 0.0664
Echinococcus multilocularis protein kinase 0.0416 1 1
Trichomonas vaginalis TKL family protein kinase 0.0416 1 1
Loa Loa (eye worm) hypothetical protein 0.0041 0.054 0.054
Echinococcus granulosus tyrosine protein kinase Src42A 0.0416 1 1
Entamoeba histolytica protein kinase, putative 0.0416 1 0.5
Loa Loa (eye worm) hypothetical protein 0.0416 1 1
Entamoeba histolytica protein kinase domain containing protein 0.0416 1 0.5
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0416 1 1
Schistosoma mansoni tyrosine kinase 0.0416 1 1
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0416 1 1
Entamoeba histolytica tyrosine kinase, putative 0.0416 1 0.5
Trypanosoma cruzi protein kinase, putative 0.0416 1 1
Plasmodium falciparum protein kinase, putative 0.0416 1 1
Giardia lamblia Kinase, NEK 0.0416 1 0.5
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0416 1 1
Loa Loa (eye worm) TK protein kinase 0.0416 1 1
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0416 1 1
Loa Loa (eye worm) TK protein kinase 0.0416 1 1
Entamoeba histolytica tyrosine kinase, putative 0.0416 1 0.5
Trichomonas vaginalis TKL family protein kinase 0.0416 1 1
Loa Loa (eye worm) MH2 domain-containing protein 0.0252 0.5854 0.5854
Loa Loa (eye worm) TK protein kinase 0.0416 1 1
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0416 1 1
Loa Loa (eye worm) hypothetical protein 0.0053 0.0826 0.0826
Loa Loa (eye worm) TK/FER protein kinase 0.0416 1 1
Schistosoma mansoni tyrosine kinase 0.0416 1 1
Entamoeba histolytica serine/threonine kinase, putative 0.0416 1 0.5
Trichomonas vaginalis TKL family protein kinase 0.0416 1 1
Loa Loa (eye worm) TK protein kinase 0.0416 1 1
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0416 1 1
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0416 1 1
Echinococcus granulosus geminin 0.0184 0.4134 0.4107
Entamoeba histolytica protein kinase domain containing protein 0.0416 1 0.5
Trichomonas vaginalis TKL family protein kinase 0.0416 1 1
Entamoeba histolytica tyrosine- protein kinase 2, putative 0.0416 1 0.5
Loa Loa (eye worm) RGC/RGC protein kinase 0.0416 1 1
Brugia malayi Protein kinase domain containing protein 0.0416 1 1
Loa Loa (eye worm) TK/FER protein kinase 0.0416 1 1
Schistosoma mansoni tyrosine kinase 0.0416 1 1
Onchocerca volvulus 0.0416 1 1
Onchocerca volvulus 0.0416 1 1
Schistosoma mansoni src-type protein tyrosine kinase-related 0.0416 1 1
Loa Loa (eye worm) TK/FER protein kinase 0.0416 1 1
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0416 1 1
Loa Loa (eye worm) glutaminase 2 0.0296 0.698 0.698
Brugia malayi C-terminal src kinase protein 1 0.0416 1 1
Trichomonas vaginalis TKL family protein kinase 0.0416 1 1
Echinococcus multilocularis SAM and MBT domain containing protein 0.0046 0.0664 0.062
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0416 1 1
Schistosoma mansoni tyrosine kinase 0.0416 1 1
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0416 1 1
Brugia malayi Bromodomain containing protein 0.0037 0.0433 0.0332
Entamoeba histolytica tyrosin kinase, putative 0.0416 1 0.5
Loa Loa (eye worm) TK protein kinase 0.0416 1 1
Trichomonas vaginalis TKL family protein kinase 0.0416 1 1
Schistosoma mansoni tyrosine kinase 0.0416 1 1
Trichomonas vaginalis TKL family protein kinase 0.0416 1 1
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0416 1 1
Trichomonas vaginalis TKL family protein kinase 0.0416 1 1
Trypanosoma brucei protein kinase, putative 0.0416 1 1
Trichomonas vaginalis TKL family protein kinase 0.0416 1 1
Brugia malayi Augmenter of liver regeneration 0.0037 0.0433 0.0332
Schistosoma mansoni tyrosine kinase 0.0416 1 1
Brugia malayi Protein kinase domain containing protein 0.0416 1 1
Entamoeba histolytica protein kinase, putative 0.0416 1 0.5
Brugia malayi Protein kinase domain containing protein 0.0416 1 1
Trichomonas vaginalis TKL family protein kinase 0.0416 1 1
Schistosoma mansoni tyrosine kinase 0.0416 1 1
Brugia malayi Bromodomain containing protein 0.0073 0.1334 0.1242
Brugia malayi Protein kinase domain containing protein 0.0416 1 1
Trichomonas vaginalis TKL family protein kinase 0.0416 1 1
Echinococcus multilocularis tyrosine kinase 0.0416 1 1
Echinococcus granulosus raf serine:threonine protein kinase 0.0416 1 1
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0056 0.0901 0.5
Schistosoma mansoni tyrosine kinase 0.0416 1 1
Loa Loa (eye worm) TK protein kinase 0.0416 1 1
Brugia malayi Protein kinase domain containing protein 0.0416 1 1
Trichomonas vaginalis CAMK family protein kinase 0.0416 1 1
Echinococcus granulosus activated cdc42 kinase 1 0.0416 1 1
Trypanosoma brucei Flagellum attachment zone protein 20 0.0416 1 1
Trichomonas vaginalis STE family protein kinase 0.0416 1 1
Schistosoma mansoni protein kinase 0.0416 1 1
Loa Loa (eye worm) TK/FER protein kinase 0.0416 1 1
Loa Loa (eye worm) hypothetical protein 0.0416 1 1
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0416 1 1
Brugia malayi Protein kinase domain containing protein 0.0416 1 1
Entamoeba histolytica protein kinase, putative 0.0416 1 0.5
Echinococcus multilocularis tyrosine protein kinase Fes:Fps 0.0416 1 1
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0416 1 1
Brugia malayi Protein kinase domain containing protein 0.0416 1 1
Trichomonas vaginalis conserved hypothetical protein 0.0416 1 1
Loa Loa (eye worm) TK/DDR protein kinase 0.0416 1 1
Brugia malayi hypothetical protein 0.0416 1 1
Echinococcus multilocularis FL cytokine receptor 0.0416 1 1
Entamoeba histolytica tyrosine kinase, putative 0.0416 1 0.5
Giardia lamblia Kinase, NEK 0.0416 1 0.5
Trichomonas vaginalis TKL family protein kinase 0.0416 1 1
Trichomonas vaginalis TKL family protein kinase 0.0416 1 1
Schistosoma mansoni tyrosine kinase 0.0416 1 1
Brugia malayi Immunoglobulin I-set domain containing protein 0.0416 1 1
Echinococcus granulosus activated cdc42 kinase 1 0.0416 1 1
Entamoeba histolytica tyrosine kinase, putative 0.0416 1 0.5
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0416 1 0.5
Trichomonas vaginalis TKL family protein kinase 0.0416 1 1
Trichomonas vaginalis TKL family protein kinase 0.0416 1 1
Echinococcus granulosus retinal guanylyl cyclase 2 0.0416 1 1
Schistosoma mansoni tyrosine kinase 0.0416 1 1
Trypanosoma brucei Pseudokinase, putative 0.0416 1 1
Loa Loa (eye worm) TK/FER protein kinase 0.0416 1 1
Entamoeba histolytica hypothetical protein 0.0416 1 0.5
Entamoeba histolytica protein kinase, putative 0.0416 1 0.5
Brugia malayi Protein kinase domain containing protein 0.0416 1 1
Trichomonas vaginalis TKL family protein kinase 0.0416 1 1
Onchocerca volvulus 0.0416 1 1
Loa Loa (eye worm) TK/FER protein kinase 0.0416 1 1
Trichomonas vaginalis TKL family protein kinase 0.0416 1 1
Onchocerca volvulus 0.0416 1 1
Trichomonas vaginalis TKL family protein kinase 0.0416 1 1
Loa Loa (eye worm) TK/FER protein kinase 0.0416 1 1
Trichomonas vaginalis TKL family protein kinase 0.0416 1 1
Echinococcus granulosus tyrosine protein kinase ABL1 0.0416 1 1
Plasmodium vivax tyrosine kinase-like protein, putative 0.0416 1 1
Trichomonas vaginalis TKL family protein kinase 0.0416 1 1
Loa Loa (eye worm) serine/threonine protein kinase 0.0416 1 1
Entamoeba histolytica leucine-rich repeat domain-containing protein 0.0416 1 0.5
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0416 1 1
Echinococcus granulosus histone acetyltransferase MYST2 0.0053 0.0826 0.0783
Trichomonas vaginalis TKL family protein kinase 0.0416 1 1
Schistosoma mansoni hypothetical protein 0.0282 0.6609 0.6609
Toxoplasma gondii protein kinase domain-containing protein 0.0416 1 1
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0416 1 1
Echinococcus multilocularis activin receptor type 0.0416 1 1
Trichomonas vaginalis TKL family protein kinase 0.0416 1 1
Trichomonas vaginalis TKL family protein kinase 0.0416 1 1
Trichomonas vaginalis TKL family protein kinase 0.0416 1 1
Onchocerca volvulus 0.0416 1 1
Echinococcus multilocularis tyrosine protein kinase csk 0.0416 1 1
Echinococcus granulosus tyrosine protein kinase csk 0.0416 1 1
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0416 1 1
Entamoeba histolytica protein kinase domain containing protein 0.0416 1 0.5
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0416 1 0.5
Toxoplasma gondii STE kinase 0.0416 1 1
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0056 0.0901 0.0859
Trichomonas vaginalis br serine/threonine-protein kinase, putative 0.0416 1 1
Loa Loa (eye worm) TK/FER protein kinase 0.0416 1 1
Loa Loa (eye worm) TK/ABL protein kinase 0.0416 1 1
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0416 1 0.5
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0416 1 0.5
Entamoeba histolytica hypothetical protein, conserved 0.0416 1 0.5
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0416 1 1
Schistosoma mansoni ephrin receptor 0.0416 1 1
Plasmodium vivax tyrosine kinase-like protein, putative 0.0416 1 1
Trichomonas vaginalis TKL family protein kinase 0.0416 1 1
Entamoeba histolytica protein kinase, putative 0.0416 1 0.5
Onchocerca volvulus 0.0416 1 1
Schistosoma mansoni tyrosine kinase 0.0416 1 1
Trichomonas vaginalis TK family protein kinase 0.0416 1 1
Entamoeba histolytica protein kinase, putative 0.0416 1 0.5
Trichomonas vaginalis conserved hypothetical protein 0.0416 1 1
Trypanosoma cruzi protein kinase, putative 0.0416 1 1
Loa Loa (eye worm) hypothetical protein 0.0069 0.1229 0.1229
Entamoeba histolytica tyrosine kinase, putative 0.0416 1 0.5
Entamoeba histolytica protein kinase, putative 0.0416 1 0.5
Echinococcus granulosus tyrosine protein kinase Lyn 0.0416 1 1
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0416 1 1
Entamoeba histolytica hypothetical protein 0.0416 1 0.5
Onchocerca volvulus 0.0416 1 1
Loa Loa (eye worm) TK/ROR protein kinase 0.0416 1 1
Trichomonas vaginalis TKL family protein kinase 0.0416 1 1
Entamoeba histolytica protein kinase domain containing protein 0.0416 1 0.5
Echinococcus multilocularis insulin receptor 0.0416 1 1
Brugia malayi Protein kinase domain containing protein 0.0416 1 1
Echinococcus multilocularis geminin 0.0184 0.4134 0.4107
Echinococcus multilocularis ephrin type A receptor 4 A 0.0416 1 1
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0044 0.0616 0.0517
Leishmania major protein kinase, putative 0.0416 1 1
Schistosoma mansoni tyrosine kinase 0.0416 1 1
Brugia malayi Guanylyl cyclase protein 23 0.0416 1 1
Brugia malayi Protein kinase domain containing protein 0.0416 1 1
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0416 1 1
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.0416 1 1
Loa Loa (eye worm) TK/FER protein kinase 0.0416 1 1
Brugia malayi hypothetical protein 0.0416 1 1
Echinococcus multilocularis tyrosine protein kinase pr2 0.0416 1 1
Trichomonas vaginalis TKL family protein kinase 0.0416 1 1
Plasmodium falciparum tyrosine kinase-like protein 0.0416 1 1
Brugia malayi proto-oncogene tyrosine-protein kinase FER 0.0416 1 1
Trichomonas vaginalis TKL family protein kinase 0.0416 1 1
Brugia malayi mbt repeat family protein 0.0046 0.0664 0.0565
Brugia malayi SRC-1 0.0416 1 1
Entamoeba histolytica protein kinase, putative 0.0416 1 0.5
Brugia malayi Protein kinase domain containing protein 0.0416 1 1
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0416 1 1
Schistosoma mansoni protein kinase 0.0416 1 1
Echinococcus granulosus ephrin type A receptor 4 A 0.0416 1 1
Leishmania major protein kinase, putative 0.0416 1 1
Echinococcus granulosus tyrosine protein kinase csk 0.0416 1 1
Plasmodium vivax protein kinase, putative 0.0416 1 1
Schistosoma mansoni tyrosine kinase 0.0416 1 1
Loa Loa (eye worm) RGC/RGC protein kinase 0.0416 1 1
Echinococcus granulosus protein tyrosine kinase 0.0416 1 1
Onchocerca volvulus 0.0416 1 1
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0416 1 1
Brugia malayi hypothetical protein 0.0234 0.5405 0.5357
Schistosoma mansoni serine/threonine protein kinase 0.0416 1 1
Echinococcus multilocularis tyrosine protein kinase 0.0416 1 1
Entamoeba histolytica tyrosin kinase, putative 0.0416 1 0.5
Loa Loa (eye worm) hypothetical protein 0.0416 1 1
Entamoeba histolytica protein kinase domain containing protein 0.0416 1 0.5
Leishmania major hypothetical protein, conserved 0.0416 1 1
Schistosoma mansoni protein kinase 0.0416 1 1
Echinococcus multilocularis tyrosine protein kinase shark 0.0416 1 1
Brugia malayi Tyrosine-protein kinase PR2 0.0416 1 1
Loa Loa (eye worm) TK/FER protein kinase 0.0416 1 1
Brugia malayi SH2 domain containing protein 0.0416 1 1
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0416 1 0.5
Trichomonas vaginalis TKL family protein kinase 0.0416 1 1
Schistosoma mansoni tyrosine kinase 0.0416 1 1
Trichomonas vaginalis TKL family protein kinase 0.0416 1 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.0616 0.0616
Loa Loa (eye worm) transcription factor SMAD2 0.0252 0.5854 0.5854
Trichomonas vaginalis TKL family protein kinase 0.0416 1 1
Entamoeba histolytica hypothetical protein 0.0416 1 0.5
Echinococcus multilocularis epidermal growth factor receptor 0.0416 1 1
Entamoeba histolytica protein kinase domain containing protein 0.0416 1 0.5
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.0416 1 1
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0416 1 1
Entamoeba histolytica protein kinase with ankyrin repeats, putative 0.0416 1 0.5
Loa Loa (eye worm) hypothetical protein 0.0416 1 1
Entamoeba histolytica protein kinase, putative 0.0416 1 0.5
Brugia malayi Protein kinase domain containing protein 0.0416 1 1
Loa Loa (eye worm) TK protein kinase 0.0416 1 1
Brugia malayi Protein kinase domain containing protein 0.0416 1 1
Loa Loa (eye worm) TK/ACK protein kinase 0.0416 1 1
Loa Loa (eye worm) MBCTL1 0.0053 0.0826 0.0826
Schistosoma mansoni tyrosine kinase 0.0416 1 1
Trichomonas vaginalis TKL family protein kinase 0.0416 1 1
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0416 1 1
Brugia malayi SH2 domain containing protein 0.0416 1 1
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0416 1 1
Trichomonas vaginalis TKL family protein kinase 0.0416 1 1
Entamoeba histolytica protein kinase, putative 0.0416 1 0.5
Loa Loa (eye worm) TK/CSK protein kinase 0.0416 1 1
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.0416 1 1
Trichomonas vaginalis protein kinase atn1, putative 0.0416 1 1
Trichomonas vaginalis TKL family protein kinase 0.0416 1 1
Brugia malayi bone morphogenetic protein type 1 receptor 0.0416 1 1
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0416 1 1
Echinococcus multilocularis tyrosine protein kinase csk 0.0416 1 1
Schistosoma mansoni tyrosine protein kinase 0.0416 1 1
Echinococcus granulosus epidermal growth factor receptor 0.0416 1 1
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0416 1 1
Trichomonas vaginalis TKL family protein kinase 0.0416 1 1
Schistosoma mansoni hypothetical protein 0.0048 0.07 0.07
Echinococcus granulosus kinase suppressor of Ras 1 0.0416 1 1
Entamoeba histolytica serine/threonine kinase, putative 0.0416 1 0.5
Trichomonas vaginalis TKL family protein kinase 0.0416 1 1
Brugia malayi Protein kinase domain containing protein 0.0416 1 1
Echinococcus multilocularis heat shock protein 70 0.0416 1 1
Entamoeba histolytica tyrosine kinase, putative 0.0416 1 0.5
Schistosoma mansoni tyrosine kinase 0.0416 1 1
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0044 0.0616 0.0572
Entamoeba histolytica tyrosin kinase, putative 0.0416 1 0.5
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0053 0.0826 0.0783
Brugia malayi Protein kinase domain containing protein 0.0416 1 1
Loa Loa (eye worm) TK protein kinase 0.0416 1 1
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0416 1 1
Entamoeba histolytica protein kinase domain containing protein 0.0416 1 0.5
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0416 1 1
Entamoeba histolytica ankyrin repeat protein 0.0416 1 0.5
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0416 1 1
Loa Loa (eye worm) TK/EPH protein kinase 0.0416 1 1
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0416 1 1
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0416 1 1
Schistosoma mansoni sex comb on midleg homolog 0.0046 0.0664 0.0664
Entamoeba histolytica protein kinase, putative 0.0416 1 0.5
Entamoeba histolytica tyrosine kinase, putative 0.0416 1 0.5
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0044 0.0616 0.0572
Brugia malayi Protein kinase domain containing protein 0.0416 1 1
Echinococcus multilocularis tyrosine protein kinase csk 0.0416 1 1
Entamoeba histolytica cysteine surface protein, putative 0.0416 1 0.5
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0416 1 1
Echinococcus multilocularis tyrosine kinase 0.0416 1 1
Brugia malayi glutaminase DH11.1 0.0296 0.698 0.6948
Echinococcus granulosus tyrosine protein kinase Fyn 0.0416 1 1
Entamoeba histolytica serine/threonine kinase, putative 0.0416 1 0.5
Trichomonas vaginalis serine/threonine-protein kinase wnk, putative 0.0416 1 1
Entamoeba histolytica protein kinase domain containing protein 0.0416 1 0.5
Brugia malayi Protein kinase domain containing protein 0.0416 1 1
Onchocerca volvulus 0.0416 1 1
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0416 1 1
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0035 0.0375 0.033
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0416 1 0.5
Brugia malayi Protein kinase domain containing protein 0.0416 1 1
Echinococcus granulosus tyrosine protein kinase shark 0.0416 1 1
Entamoeba histolytica serine/threonine kinase, putative 0.0416 1 0.5
Brugia malayi hypothetical protein 0.0416 1 1
Echinococcus granulosus tyrosine kinase 0.0416 1 1
Entamoeba histolytica receptor protein kinase, putative 0.0416 1 0.5
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0022 0.0047 0.0047
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0416 1 1
Loa Loa (eye worm) TK/FER protein kinase 0.0416 1 1
Trichomonas vaginalis TKL family protein kinase 0.0416 1 1
Loa Loa (eye worm) hypothetical protein 0.0416 1 1
Schistosoma mansoni serine/threonine protein kinase 0.0416 1 1
Trichomonas vaginalis TKL family protein kinase 0.0416 1 1
Entamoeba histolytica protein kinase domain containing protein 0.0416 1 0.5
Echinococcus multilocularis protein KINase family member (kin 25) 0.0416 1 1
Entamoeba histolytica tyrosine kinase, putative 0.0416 1 0.5
Trichomonas vaginalis conserved hypothetical protein 0.0416 1 1
Echinococcus granulosus protein kinase 0.0416 1 1
Entamoeba histolytica protein kinase domain containing protein 0.0416 1 0.5
Trichomonas vaginalis TKL family protein kinase 0.0416 1 1
Echinococcus multilocularis tyrosine protein kinase csk 0.0416 1 1
Trichomonas vaginalis TKL family protein kinase 0.0416 1 1
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.0416 1 1
Entamoeba histolytica protein kinase, putative 0.0416 1 0.5
Entamoeba histolytica tyrosin kinase, putative 0.0416 1 0.5
Entamoeba histolytica protein kinase domain containing protein 0.0416 1 0.5
Echinococcus multilocularis tyrosine protein kinase Blk 0.0416 1 1
Schistosoma mansoni tyrosine kinase 0.0416 1 1
Entamoeba histolytica protein kinase domain containing protein 0.0416 1 0.5
Trichomonas vaginalis TKL family protein kinase 0.0416 1 1
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0416 1 1
Echinococcus granulosus tyrosine kinase 0.0416 1 1
Entamoeba histolytica protein kinase domain containing protein 0.0416 1 0.5
Trichomonas vaginalis TKL family protein kinase 0.0416 1 1
Entamoeba histolytica receptor protein kinase, putative 0.0416 1 0.5
Trichomonas vaginalis TKL family protein kinase 0.0416 1 1
Trypanosoma brucei AGC/RSK family serine/threonine kinase, putative 0.0416 1 1
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0416 1 1
Trichomonas vaginalis TKL family protein kinase 0.0416 1 1
Echinococcus multilocularis tyrosine protein kinase HCK 0.0416 1 1
Echinococcus multilocularis integrin linked protein kinase 0.0416 1 1
Echinococcus granulosus tyrosine protein kinase csk 0.0416 1 1
Trichomonas vaginalis TKL family protein kinase 0.0416 1 1
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0058 0.0959 0.0916
Loa Loa (eye worm) TK/FAK protein kinase 0.0416 1 1
Plasmodium falciparum protein kinase, putative 0.0416 1 1
Schistosoma mansoni protein kinase 0.0416 1 1
Echinococcus granulosus insulin receptor 0.0416 1 1
Trichomonas vaginalis TKL family protein kinase 0.0416 1 1
Mycobacterium ulcerans glutaminase 0.0296 0.698 1
Entamoeba histolytica protein kinase, putative 0.0416 1 0.5
Entamoeba histolytica protein kinase domain containing protein 0.0416 1 0.5
Brugia malayi Protein kinase domain containing protein 0.0416 1 1
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0416 1 1
Echinococcus multilocularis raf serine:threonine protein kinase 0.0416 1 1
Trichomonas vaginalis conserved hypothetical protein 0.0416 1 1
Echinococcus granulosus natriuretic peptide receptor 1 0.0416 1 1
Loa Loa (eye worm) hepatopoietin HPO2 0.0037 0.0433 0.0433
Echinococcus multilocularis transfer RNA-Thr 0.0416 1 1
Echinococcus granulosus activin receptor type 0.0416 1 1
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.0416 1 1
Schistosoma mansoni tyrosine kinase 0.0416 1 1
Trichomonas vaginalis conserved hypothetical protein 0.0416 1 1
Loa Loa (eye worm) hypothetical protein 0.0416 1 1
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0035 0.0375 0.033
Trichomonas vaginalis TKL family protein kinase 0.0416 1 1
Schistosoma mansoni tyrosine kinase 0.0416 1 1
Schistosoma mansoni survival motor neuron protein 0.0048 0.07 0.07
Echinococcus granulosus receptor type guanylyl cyclase 0.0416 1 1
Echinococcus granulosus integrin linked protein kinase 0.0416 1 1
Entamoeba histolytica tyrosine kinase, putative 0.0416 1 0.5
Entamoeba histolytica protein kinase domain containing protein 0.0416 1 0.5
Schistosoma mansoni protein kinase 0.0416 1 1
Entamoeba histolytica protein kinase domain containing protein 0.0416 1 0.5
Echinococcus multilocularis tyrosine protein kinase Abl 0.0416 1 1
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0053 0.0826 0.0729
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0056 0.0901 0.0859
Entamoeba histolytica protein kinase, putative 0.0416 1 0.5
Entamoeba histolytica protein kinase, putative 0.0416 1 0.5
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0058 0.0959 0.0916
Brugia malayi MH2 domain containing protein 0.0252 0.5854 0.581
Echinococcus multilocularis natriuretic peptide receptor 1 0.0416 1 1
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0416 1 1
Entamoeba histolytica hypothetical protein 0.0416 1 0.5
Onchocerca volvulus Tyrosine kinase homolog 0.0416 1 1
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.0416 1 1
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.0416 1 1
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0416 1 1
Trichomonas vaginalis TKL family protein kinase 0.0416 1 1

Activities

Activity type Activity value Assay description Source Reference
IC50 (ADMET) = 13 uM Cytotoxicity against human H9 cells after 3 days ChEMBL. 7494144

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Homo sapiens ChEMBL23 7494144

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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