Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0027 | 0.0027 |
Trypanosoma brucei | peptidyl-prolyl cis-trans isomerase/rotamase, putative | 0.0035 | 0.0093 | 0.2085 |
Plasmodium vivax | lysine-specific histone demethylase 1, putative | 0.0023 | 0.0027 | 0.0045 |
Leishmania major | hypothetical protein, conserved | 0.0024 | 0.0036 | 0.0799 |
Plasmodium falciparum | protoporphyrinogen oxidase | 0.0023 | 0.0027 | 0.048 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0065 | 0.0243 | 0.544 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0087 | 0.0354 | 0.7919 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0599 | 0.2961 | 0.3463 |
Loa Loa (eye worm) | hypothetical protein | 0.0287 | 0.1372 | 0.1372 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0599 | 0.2961 | 0.3463 |
Echinococcus multilocularis | nicotinic acetylcholine receptor subunit type | 0.0287 | 0.1372 | 0.3146 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0087 | 0.0354 | 0.7919 |
Brugia malayi | acetylcholine receptor alpha subunit precursor, putative | 0.0599 | 0.2961 | 0.3463 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.005 | 0.0166 | 0.0166 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0599 | 0.2961 | 0.3463 |
Schistosoma mansoni | nAChR subunit | 0.0287 | 0.1372 | 0.4634 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0027 | 0.0027 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0076 | 0.0076 |
Schistosoma mansoni | nAChR subunit (ShAR1-beta2-like) | 0.0599 | 0.2961 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0105 | 0.0446 | 0.36 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.005 | 0.0166 | 0.056 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0287 | 0.1372 | 0.1605 |
Schistosoma mansoni | amine oxidase | 0.0023 | 0.0027 | 0.0092 |
Entamoeba histolytica | serine/threonine protein kinase, putative | 0.0105 | 0.0446 | 0.2899 |
Schistosoma mansoni | hypothetical protein | 0.0129 | 0.0568 | 0.1919 |
Schistosoma mansoni | ap endonuclease | 0.002 | 0.0016 | 0.0053 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0063 | 0.0232 | 0.0784 |
Schistosoma mansoni | nAChR subunit (ShAR1-alpha-like) | 0.0599 | 0.2961 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0053 | 0.0182 | 0.1393 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0085 | 0.0347 | 0.0406 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0087 | 0.0354 | 0.7919 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0105 | 0.0446 | 0.1508 |
Onchocerca volvulus | 0.0287 | 0.1372 | 0.4584 | |
Toxoplasma gondii | ImpB/MucB/SamB family protein | 0.0018 | 0.0004 | 0.0066 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0087 | 0.0354 | 0.7919 |
Onchocerca volvulus | Serine\/threonine kinase homolog | 0.0105 | 0.0446 | 0.1429 |
Loa Loa (eye worm) | hypothetical protein | 0.0287 | 0.1372 | 0.1372 |
Trypanosoma brucei | DNA damage repair protein, putative | 0.0018 | 0.0004 | 0.0083 |
Loa Loa (eye worm) | hypothetical protein | 0.0599 | 0.2961 | 0.2961 |
Echinococcus granulosus | nicotinic acetylcholine receptor a11 subunit | 0.0599 | 0.2961 | 1 |
Schistosoma mansoni | amine oxidase | 0.0023 | 0.0027 | 0.0092 |
Echinococcus granulosus | glycine receptor subunit alpha 1 | 0.0599 | 0.2961 | 1 |
Schistosoma mansoni | nAChR subunit | 0.0287 | 0.1372 | 0.4634 |
Loa Loa (eye worm) | hypothetical protein | 0.0287 | 0.1372 | 0.1372 |
Brugia malayi | SWIRM domain containing protein | 0.0023 | 0.0027 | 0.0032 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0018 | 0.0004 | 0.0083 |
Leishmania major | peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative | 0.0035 | 0.0093 | 0.2085 |
Onchocerca volvulus | 0.0599 | 0.2961 | 1 | |
Onchocerca volvulus | Putative endochitinase | 0.0091 | 0.0375 | 0.1186 |
Schistosoma mansoni | DNA polymerase eta | 0.0085 | 0.0347 | 0.1173 |
Loa Loa (eye worm) | hypothetical protein | 0.0599 | 0.2961 | 0.2961 |
Onchocerca volvulus | Putative endochitinase | 0.0081 | 0.0326 | 0.1017 |
Loa Loa (eye worm) | hypothetical protein | 0.0599 | 0.2961 | 0.2961 |
Trypanosoma cruzi | telomerase reverse transcriptase, putative | 0.0083 | 0.0333 | 0.7467 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0023 | 0.0027 | 0.0191 |
Onchocerca volvulus | 0.0599 | 0.2961 | 1 | |
Loa Loa (eye worm) | nicotinic acetylcholine receptor alpha subunit | 0.0599 | 0.2961 | 0.2961 |
Brugia malayi | Hypothetical glycine receptor like protein T20B12.9 in chromosome III | 0.0312 | 0.1502 | 0.1756 |
Mycobacterium ulcerans | flavin-containing monoamine oxidase AofH | 0.032 | 0.1542 | 1 |
Plasmodium vivax | telomerase reverse transcriptase, putative | 0.0083 | 0.0333 | 0.0545 |
Toxoplasma gondii | hypothetical protein | 0.0129 | 0.0568 | 1 |
Trypanosoma cruzi | UDP-galactopyranose mutase | 0.0023 | 0.0027 | 0.0611 |
Echinococcus granulosus | Hepatocellular carcinoma associated antigen 59 | 0.0129 | 0.0568 | 0.1919 |
Loa Loa (eye worm) | hypothetical protein | 0.0287 | 0.1372 | 0.1372 |
Brugia malayi | hypothetical protein | 0.0287 | 0.1372 | 0.1605 |
Echinococcus granulosus | acetylcholine receptor subunit beta 1 | 0.0599 | 0.2961 | 1 |
Echinococcus granulosus | dna polymerase kappa | 0.0087 | 0.0354 | 0.1194 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0047 | 0.0151 | 0.3381 |
Echinococcus granulosus | glycine receptor subunit alpha 1 | 0.0599 | 0.2961 | 1 |
Plasmodium vivax | DNA repair protein REV1, putative | 0.0018 | 0.0004 | 0.0006 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0058 | 0.0206 | 0.0241 |
Schistosoma mansoni | hypothetical protein | 0.0595 | 0.2941 | 0.9932 |
Echinococcus granulosus | nicotinic acetylcholine receptor subunit alpha 8 | 0.0599 | 0.2961 | 1 |
Brugia malayi | hypothetical protein | 0.0078 | 0.0309 | 0.0361 |
Loa Loa (eye worm) | AUR protein kinase | 0.0063 | 0.0232 | 0.0232 |
Brugia malayi | nicotinic acetylcholine receptor alpha subunit, putative | 0.0599 | 0.2961 | 0.3463 |
Mycobacterium ulcerans | oxidoreductase | 0.0023 | 0.0027 | 0.0153 |
Mycobacterium tuberculosis | Possible chitinase | 0.0069 | 0.0265 | 0.1855 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.0298 | 0.0298 |
Loa Loa (eye worm) | neuronal acetylcholine receptor protein | 0.0287 | 0.1372 | 0.1372 |
Onchocerca volvulus | 0.0255 | 0.1212 | 0.4038 | |
Mycobacterium ulcerans | DNA polymerase IV | 0.0087 | 0.0354 | 0.2275 |
Echinococcus multilocularis | terminal deoxycytidyl transferase rev1 | 0.0058 | 0.0206 | 0.0473 |
Trichomonas vaginalis | AGC family protein kinase | 0.0063 | 0.0232 | 0.1809 |
Plasmodium falciparum | serine/threonine protein kinase, putative | 0.0063 | 0.0232 | 0.4086 |
Toxoplasma gondii | ImpB/MucB/SamB family protein | 0.0046 | 0.0145 | 0.2547 |
Loa Loa (eye worm) | hypothetical protein | 0.0069 | 0.0265 | 0.0265 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0078 | 0.0309 | 0.1044 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0105 | 0.0446 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0599 | 0.2961 | 0.2961 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.005 | 0.0166 | 0.056 |
Echinococcus granulosus | terminal deoxycytidyl transferase rev1 | 0.0058 | 0.0206 | 0.0697 |
Plasmodium vivax | tryptophan-rich antigen (Pv-fam-a) | 0.1218 | 0.6116 | 1 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0105 | 0.0446 | 1 |
Echinococcus granulosus | lysine specific histone demethylase 1A | 0.0023 | 0.0027 | 0.0092 |
Schistosoma mansoni | flap endonuclease-1 | 0.0026 | 0.0043 | 0.0145 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.002 | 0.0016 | 0.0053 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0032 | 0.0076 | 0.0258 |
Brugia malayi | hypothetical protein | 0.0023 | 0.0027 | 0.0032 |
Onchocerca volvulus | 0.0312 | 0.1502 | 0.5025 | |
Brugia malayi | excitatory GABA receptor EXP-1A | 0.0599 | 0.2961 | 0.3463 |
Entamoeba histolytica | protein kinase domain containing protein | 0.0063 | 0.0232 | 0.1457 |
Giardia lamblia | Aurora kinase | 0.0063 | 0.0232 | 0.516 |
Schistosoma mansoni | acetylcholine receptor-related | 0.0287 | 0.1372 | 0.4634 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0027 | 0.0027 |
Echinococcus multilocularis | nicotinic acetylcholine receptor subunit alpha 8 | 0.0599 | 0.2961 | 0.679 |
Loa Loa (eye worm) | hypothetical protein | 0.0312 | 0.1502 | 0.1502 |
Echinococcus granulosus | aurora kinase A | 0.0063 | 0.0232 | 0.0784 |
Schistosoma mansoni | kinase | 0.0054 | 0.0189 | 0.0639 |
Toxoplasma gondii | RNA-directed DNA polymerase | 0.0083 | 0.0333 | 0.5866 |
Schistosoma mansoni | neurotransmitter gated ion channel | 0.0287 | 0.1372 | 0.4634 |
Trypanosoma brucei | flap endonuclease-1 (FEN-1), putative | 0.0028 | 0.0057 | 0.127 |
Trypanosoma cruzi | Vps23 core domain containing protein, putative | 0.0024 | 0.0036 | 0.0799 |
Brugia malayi | Cation transporter family protein | 0.0599 | 0.2961 | 0.3463 |
Leishmania major | DNA polymerase kappa, putative | 0.0018 | 0.0004 | 0.0083 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0031 | 0.007 | 0.0237 |
Echinococcus multilocularis | flap endonuclease 1 | 0.0028 | 0.0057 | 0.013 |
Loa Loa (eye worm) | hypothetical protein | 0.0287 | 0.1372 | 0.1372 |
Schistosoma mansoni | nAChR subunit | 0.0599 | 0.2961 | 1 |
Echinococcus multilocularis | nicotinic acetylcholine receptor alpha subunit | 0.0599 | 0.2961 | 0.679 |
Loa Loa (eye worm) | indoleamine 2,3-dioxygenase | 0.0595 | 0.2941 | 0.2941 |
Schistosoma mansoni | Lysine-specific histone demethylase 1 | 0.0023 | 0.0027 | 0.0092 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0036 | 0.0097 | 0.0683 |
Loa Loa (eye worm) | hypothetical protein | 0.0287 | 0.1372 | 0.1372 |
Trichomonas vaginalis | hypothetical protein | 0.0037 | 0.01 | 0.0705 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.0065 | 0.0243 | 0.1702 |
Echinococcus granulosus | expressed protein | 0.0036 | 0.0097 | 0.0329 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.0058 | 0.0206 | 0.0697 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0287 | 0.1372 | 0.1605 |
Loa Loa (eye worm) | chitinase I | 0.0081 | 0.0326 | 0.0326 |
Echinococcus granulosus | lysine specific histone demethylase 1A | 0.0023 | 0.0027 | 0.0092 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0047 | 0.0152 | 0.3398 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0287 | 0.1372 | 0.1605 |
Brugia malayi | hypothetical protein | 0.0287 | 0.1372 | 0.1605 |
Schistosoma mansoni | survival motor neuron protein | 0.0052 | 0.0177 | 0.0598 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0032 | 0.0076 | 0.0258 |
Schistosoma mansoni | nAChR subunit | 0.0599 | 0.2961 | 1 |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.0065 | 0.0243 | 0.544 |
Echinococcus multilocularis | glycine receptor subunit alpha 1 | 0.0599 | 0.2961 | 0.679 |
Onchocerca volvulus | 0.0129 | 0.0568 | 0.1844 | |
Echinococcus multilocularis | nAChR subunit | 0.0312 | 0.1502 | 0.3443 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0032 | 0.0076 | 0.0175 |
Entamoeba histolytica | serine/threonine- protein kinase 6, putative | 0.0063 | 0.0232 | 0.1457 |
Loa Loa (eye worm) | hypothetical protein | 0.0287 | 0.1372 | 0.1372 |
Trichomonas vaginalis | flap endonuclease-1, putative | 0.0028 | 0.0057 | 0.0343 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0027 | 0.0027 |
Echinococcus granulosus | proto oncogene serine:threonine protein kinase | 0.0174 | 0.0797 | 0.2692 |
Leishmania major | protein kinase, putative | 0.0063 | 0.0232 | 0.52 |
Schistosoma mansoni | Protoporphyrinogen oxidase chloroplast/mitochondrial precursor | 0.0023 | 0.0027 | 0.0092 |
Echinococcus multilocularis | nicotinic acetylcholine receptor a11 subunit | 0.0599 | 0.2961 | 0.679 |
Echinococcus multilocularis | atpase aaa+ type core atpase aaa type core | 0.0873 | 0.4361 | 1 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0087 | 0.0354 | 0.7919 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0312 | 0.1502 | 0.1756 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0087 | 0.0354 | 0.2275 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0032 | 0.0076 | 0.0175 |
Entamoeba histolytica | serine/threonine- protein kinase 6 , putative | 0.0063 | 0.0232 | 0.1457 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0255 | 0.121 | 0.4086 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.005 | 0.0166 | 0.056 |
Loa Loa (eye worm) | hypothetical protein | 0.0599 | 0.2961 | 0.2961 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0027 | 0.0027 |
Echinococcus granulosus | flap endonuclease 1 | 0.0028 | 0.0057 | 0.0191 |
Echinococcus multilocularis | lysine specific histone demethylase 1A | 0.0023 | 0.0027 | 0.0063 |
Trypanosoma brucei | CMGC/DYRK protein kinase, putative | 0.0098 | 0.0412 | 0.9235 |
Toxoplasma gondii | peptidylprolyl isomerase | 0.0035 | 0.0093 | 0.1638 |
Loa Loa (eye worm) | hypothetical protein | 0.0287 | 0.1372 | 0.1372 |
Brugia malayi | glutamate-gated chloride channel alpha3A subunit, putative | 0.0287 | 0.1372 | 0.1605 |
Schistosoma mansoni | neurotransmitter gated ion channel | 0.0287 | 0.1372 | 0.4634 |
Brugia malayi | hypothetical protein | 0.0076 | 0.0298 | 0.0348 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0599 | 0.2961 | 0.3463 |
Plasmodium falciparum | DNA repair protein REV1, putative | 0.0018 | 0.0004 | 0.0066 |
Trypanosoma cruzi | aurora B kinase, putative | 0.0063 | 0.0232 | 0.52 |
Plasmodium vivax | flap endonuclease 1, putative | 0.0028 | 0.0057 | 0.0093 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0105 | 0.0446 | 0.36 |
Loa Loa (eye worm) | hypothetical protein | 0.0096 | 0.04 | 0.04 |
Leishmania major | serine/threonine-protein kinase, putative,protein kinase, putative | 0.0098 | 0.0412 | 0.9235 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.005 | 0.0166 | 0.038 |
Echinococcus multilocularis | dual specificity | 0.0098 | 0.0412 | 0.0945 |
Entamoeba histolytica | hypothetical protein | 0.0078 | 0.0309 | 0.1974 |
Schistosoma mansoni | DNA polymerase IV / kappa | 0.0018 | 0.0004 | 0.0013 |
Brugia malayi | Telomerase reverse transcriptase | 0.022 | 0.1032 | 0.1207 |
Brugia malayi | Acetylcholine receptor protein, alpha-like chain 1 precursor | 0.0287 | 0.1372 | 0.1605 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0078 | 0.0309 | 0.0709 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0224 | 0.1054 | 0.1054 |
Schistosoma mansoni | hypothetical protein | 0.0367 | 0.178 | 0.6012 |
Loa Loa (eye worm) | AUR protein kinase | 0.0063 | 0.0232 | 0.0232 |
Loa Loa (eye worm) | hypothetical protein | 0.0287 | 0.1372 | 0.1372 |
Onchocerca volvulus | Putative endochitinase | 0.0091 | 0.0375 | 0.1186 |
Leishmania major | flap endonuclease-1 (FEN-1), putative | 0.0028 | 0.0057 | 0.127 |
Plasmodium vivax | hypothetical protein, conserved | 0.0129 | 0.0568 | 0.0929 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0087 | 0.0354 | 0.7919 |
Brugia malayi | Serine/threonine-protein kinase Pim-3 | 0.0174 | 0.0797 | 0.0932 |
Toxoplasma gondii | histone lysine-specific demethylase LSD1/BHC110/KDMA1A | 0.0023 | 0.0027 | 0.048 |
Entamoeba histolytica | protein kinase, putative | 0.0063 | 0.0232 | 0.1457 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0087 | 0.0354 | 0.7919 |
Plasmodium falciparum | lysine-specific histone demethylase 1, putative | 0.0023 | 0.0027 | 0.048 |
Plasmodium falciparum | flap endonuclease 1 | 0.0028 | 0.0057 | 0.0998 |
Echinococcus multilocularis | glycine receptor subunit alpha 1 | 0.0599 | 0.2961 | 0.679 |
Loa Loa (eye worm) | hypothetical protein | 0.0287 | 0.1372 | 0.1372 |
Trichomonas vaginalis | rotamase, putative | 0.0035 | 0.0093 | 0.0647 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.002 | 0.0016 | 0.5 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0087 | 0.0354 | 0.7919 |
Toxoplasma gondii | aurora kinase | 0.0063 | 0.0232 | 0.4086 |
Loa Loa (eye worm) | hypothetical protein | 0.0312 | 0.1502 | 0.1502 |
Onchocerca volvulus | 0.0312 | 0.1502 | 0.5025 | |
Toxoplasma gondii | flap structure-specific endonuclease 1, putative | 0.0028 | 0.0057 | 0.0998 |
Mycobacterium ulcerans | chitinase/cellulase | 0.0069 | 0.0265 | 0.1697 |
Echinococcus multilocularis | neuronal acetylcholine receptor subunit alpha 4 | 0.0599 | 0.2961 | 0.679 |
Loa Loa (eye worm) | GABA receptor subunit | 0.0312 | 0.1502 | 0.1502 |
Echinococcus granulosus | Cys loop ligand gated ion channel subunit | 0.0599 | 0.2961 | 1 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0599 | 0.2961 | 0.3463 |
Onchocerca volvulus | 0.0599 | 0.2961 | 1 | |
Schistosoma mansoni | hypothetical protein | 0.0595 | 0.2941 | 0.9932 |
Entamoeba histolytica | hypothetical protein | 0.0078 | 0.0309 | 0.1974 |
Entamoeba histolytica | hypothetical protein | 0.0312 | 0.1502 | 1 |
Leishmania major | protein kinase, putative,polo-like protein kinase, putative | 0.0105 | 0.0446 | 1 |
Entamoeba histolytica | deoxycytidyl transferase, putative | 0.0058 | 0.0206 | 0.1283 |
Echinococcus multilocularis | glycine receptor subunit beta | 0.0599 | 0.2961 | 0.679 |
Onchocerca volvulus | 0.0599 | 0.2961 | 1 | |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.002 | 0.0016 | 0.0352 |
Loa Loa (eye worm) | hypothetical protein | 0.0085 | 0.0347 | 0.0347 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0599 | 0.2961 | 0.3463 |
Brugia malayi | acetylcholine receptor, alpha-type subunit unc-38 precursor | 0.0599 | 0.2961 | 0.3463 |
Trichomonas vaginalis | AGC family protein kinase | 0.0063 | 0.0232 | 0.1809 |
Loa Loa (eye worm) | acetylcholine receptor alpha subunit | 0.0599 | 0.2961 | 0.2961 |
Loa Loa (eye worm) | hypothetical protein | 0.0312 | 0.1502 | 0.1502 |
Echinococcus multilocularis | dna polymerase eta | 0.0085 | 0.0347 | 0.0796 |
Entamoeba histolytica | peptidyl-prolyl cis-trans isomerase, putative | 0.0035 | 0.0093 | 0.0521 |
Onchocerca volvulus | Putative endochitinase | 0.0091 | 0.0375 | 0.1186 |
Onchocerca volvulus | 0.0287 | 0.1372 | 0.4584 | |
Schistosoma mansoni | nAChR subunit | 0.0599 | 0.2961 | 1 |
Trypanosoma brucei | Vps23 core domain containing protein, putative | 0.0024 | 0.0036 | 0.0799 |
Loa Loa (eye worm) | hypothetical protein | 0.0287 | 0.1372 | 0.1372 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.0312 | 0.1502 | 0.5071 |
Plasmodium vivax | hypothetical protein, conserved | 0.0023 | 0.0027 | 0.0045 |
Trypanosoma brucei | aurora B kinase | 0.0063 | 0.0232 | 0.52 |
Echinococcus multilocularis | dna polymerase kappa | 0.0087 | 0.0354 | 0.0811 |
Entamoeba histolytica | hypothetical protein | 0.0078 | 0.0309 | 0.1974 |
Loa Loa (eye worm) | hypothetical protein | 0.0599 | 0.2961 | 0.2961 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0312 | 0.1502 | 0.1756 |
Brugia malayi | Protein kinase domain containing protein | 0.0174 | 0.0797 | 0.0932 |
Schistosoma mansoni | hypothetical protein | 0.0052 | 0.0177 | 0.0598 |
Trypanosoma cruzi | peptidyl-prolyl cis-trans isomerase | 0.0035 | 0.0093 | 0.2085 |
Echinococcus granulosus | serine:threonine protein kinase 12 B | 0.0063 | 0.0232 | 0.0784 |
Trichomonas vaginalis | rotamase, putative | 0.0036 | 0.0097 | 0.0683 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0078 | 0.0309 | 0.1044 |
Loa Loa (eye worm) | hypothetical protein | 0.0599 | 0.2961 | 0.2961 |
Schistosoma mansoni | ap endonuclease | 0.002 | 0.0016 | 0.0053 |
Loa Loa (eye worm) | ACC-1 protein | 0.0599 | 0.2961 | 0.2961 |
Echinococcus multilocularis | glycine receptor subunit alpha 1 | 0.0599 | 0.2961 | 0.679 |
Trypanosoma brucei | unspecified product | 0.0079 | 0.0317 | 0.7101 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0079 | 0.0317 | 0.7101 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0098 | 0.0412 | 0.1392 |
Trypanosoma brucei | unspecified product | 0.004 | 0.0115 | 0.2579 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.0599 | 0.2961 | 1 |
Schistosoma mansoni | rotamase | 0.0036 | 0.0097 | 0.0329 |
Brugia malayi | hypothetical protein | 0.0287 | 0.1372 | 0.1605 |
Brugia malayi | Hepatocellular carcinoma-associated antigen 59 family protein | 0.0129 | 0.0568 | 0.0664 |
Toxoplasma gondii | histone lysine-specific demethylase | 0.0023 | 0.0027 | 0.048 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0018 | 0.0004 | 0.0083 |
Loa Loa (eye worm) | hypothetical protein | 0.0255 | 0.121 | 0.121 |
Plasmodium vivax | hypothetical protein, conserved | 0.0023 | 0.0027 | 0.0045 |
Brugia malayi | indoleamine 2,3-dioxygenase | 0.0595 | 0.2941 | 0.344 |
Echinococcus multilocularis | nicotinic acetylcholine receptor beta 1 subunit | 0.0599 | 0.2961 | 0.679 |
Loa Loa (eye worm) | ACC-1 protein | 0.0599 | 0.2961 | 0.2961 |
Loa Loa (eye worm) | glutamate-gated chloride channel alpha3A subunit | 0.0599 | 0.2961 | 0.2961 |
Schistosoma mansoni | nAChR subunit | 0.0599 | 0.2961 | 1 |
Echinococcus granulosus | glycine receptor subunit beta | 0.0599 | 0.2961 | 1 |
Trypanosoma cruzi | DNA damage repair protein, putative | 0.0018 | 0.0004 | 0.0083 |
Schistosoma mansoni | hypothetical protein | 0.0367 | 0.178 | 0.6012 |
Mycobacterium ulcerans | dehydrogenase | 0.0023 | 0.0027 | 0.0153 |
Loa Loa (eye worm) | ligand-Gated ion Channel family member | 0.0599 | 0.2961 | 0.2961 |
Loa Loa (eye worm) | hypothetical protein | 0.0287 | 0.1372 | 0.1372 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.005 | 0.0166 | 0.0194 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.005 | 0.0166 | 0.056 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0047 | 0.0152 | 0.3398 |
Plasmodium vivax | SET domain protein, putative | 0.0032 | 0.0076 | 0.0125 |
Entamoeba histolytica | protein kinase, putative | 0.0063 | 0.0232 | 0.1457 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0255 | 0.121 | 0.2774 |
Loa Loa (eye worm) | hypothetical protein | 0.0312 | 0.1502 | 0.1502 |
Brugia malayi | N-terminal motif family protein | 0.0196 | 0.0912 | 0.1066 |
Loa Loa (eye worm) | nicotinic acetylcholine receptor non-alpha subunit | 0.0599 | 0.2961 | 0.2961 |
Loa Loa (eye worm) | microfilarial chitinase | 0.0079 | 0.0315 | 0.0315 |
Echinococcus multilocularis | serine:threonine protein kinase PLK1 | 0.0105 | 0.0446 | 0.1024 |
Entamoeba histolytica | protein kinase, putative | 0.0098 | 0.0412 | 0.2669 |
Brugia malayi | Pre-SET motif family protein | 0.0224 | 0.1054 | 0.1233 |
Leishmania major | DNA damage repair protein, putative | 0.0018 | 0.0004 | 0.0083 |
Onchocerca volvulus | Putative endochitinase | 0.0081 | 0.0326 | 0.1017 |
Plasmodium vivax | serine/threonine protein kinase 6, putative | 0.0063 | 0.0232 | 0.038 |
Schistosoma mansoni | neurotransmitter gated ion channel | 0.0312 | 0.1502 | 0.5071 |
Brugia malayi | hypothetical protein | 0.0255 | 0.121 | 0.1415 |
Onchocerca volvulus | 0.0032 | 0.0076 | 0.0167 | |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.002 | 0.0016 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.0098 | 0.0412 | 0.2669 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.002 | 0.0016 | 0.0016 |
Chlamydia trachomatis | protoporphyrinogen oxidase | 0.0023 | 0.0027 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0287 | 0.1372 | 0.1372 |
Loa Loa (eye worm) | hypothetical protein | 0.0096 | 0.04 | 0.04 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0053 | 0.0182 | 0.1393 |
Brugia malayi | hypothetical protein | 0.0287 | 0.1372 | 0.1605 |
Mycobacterium ulcerans | protoporphyrinogen oxidase | 0.0023 | 0.0027 | 0.0153 |
Loa Loa (eye worm) | PLK/PLK1 protein kinase | 0.0105 | 0.0446 | 0.0446 |
Entamoeba histolytica | protein kinase domain containing protein | 0.0098 | 0.0412 | 0.2669 |
Brugia malayi | Endochitinase | 0.0091 | 0.0375 | 0.0439 |
Schistosoma mansoni | protein kinase | 0.0063 | 0.0232 | 0.0784 |
Echinococcus multilocularis | tumor susceptibility gene 101 protein | 0.0076 | 0.0298 | 0.0682 |
Echinococcus granulosus | nAChR subunit | 0.0599 | 0.2961 | 1 |
Echinococcus granulosus | gamma aminobutyric acid receptor subunit | 0.0287 | 0.1372 | 0.4634 |
Loa Loa (eye worm) | acetylcholine receptor protein | 0.0287 | 0.1372 | 0.1372 |
Plasmodium falciparum | conserved Plasmodium protein, unknown function | 0.0023 | 0.0027 | 0.048 |
Echinococcus multilocularis | nAChR subunit | 0.0599 | 0.2961 | 0.679 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0599 | 0.2961 | 0.3463 |
Onchocerca volvulus | 0.0052 | 0.0177 | 0.0511 | |
Mycobacterium tuberculosis | Possible oxidoreductase | 0.0023 | 0.0027 | 0.0191 |
Loa Loa (eye worm) | hypothetical protein | 0.0196 | 0.0912 | 0.0912 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0087 | 0.0354 | 0.7919 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0105 | 0.0446 | 0.36 |
Loa Loa (eye worm) | excitatory GABA receptor EXP-1A | 0.0599 | 0.2961 | 0.2961 |
Onchocerca volvulus | Putative nachr subunit | 0.0599 | 0.2961 | 1 |
Plasmodium vivax | protoporphyrinogen oxidase, putative | 0.0023 | 0.0027 | 0.0045 |
Loa Loa (eye worm) | hypothetical protein | 0.0287 | 0.1372 | 0.1372 |
Brugia malayi | endochitinase | 0.0091 | 0.0375 | 0.0439 |
Schistosoma mansoni | nAChR subunit | 0.0599 | 0.2961 | 1 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0085 | 0.0347 | 0.7781 |
Brugia malayi | Protein kinase domain containing protein | 0.0098 | 0.0412 | 0.0482 |
Echinococcus multilocularis | proto oncogene serine:threonine protein kinase | 0.0174 | 0.0797 | 0.1828 |
Schistosoma mansoni | tsg101-related | 0.0063 | 0.0233 | 0.0787 |
Trypanosoma brucei | DNA damage repair protein, putative | 0.0018 | 0.0004 | 0.0083 |
Loa Loa (eye worm) | CAMK/PIM protein kinase | 0.0174 | 0.0797 | 0.0797 |
Trypanosoma brucei | telomerase reverse transcriptase | 0.0083 | 0.0333 | 0.7467 |
Echinococcus granulosus | geminin | 0.0367 | 0.178 | 0.6012 |
Mycobacterium leprae | PROBABLE PROTOPORPHYRINOGEN OXIDASE HEMY (PROTOPORPHYRINOGEN-IX OXIDASE) (PROTOPORPHYRINOGENASE) (PPO) | 0.0023 | 0.0027 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0312 | 0.1502 | 0.1502 |
Echinococcus granulosus | serine:threonine protein kinase PLK1 | 0.0105 | 0.0446 | 0.1508 |
Toxoplasma gondii | exonuclease III APE | 0.002 | 0.0016 | 0.0277 |
Entamoeba histolytica | protein kinase , putative | 0.0063 | 0.0232 | 0.1457 |
Schistosoma mansoni | hypothetical protein | 0.0078 | 0.0309 | 0.1044 |
Loa Loa (eye worm) | glutamate-gated chloride channel alpha3A subunit | 0.0287 | 0.1372 | 0.1372 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.0599 | 0.2961 | 1 |
Giardia lamblia | DINP protein human, muc B family | 0.0065 | 0.0243 | 0.5402 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0018 | 0.0004 | 0.0083 |
Brugia malayi | Cation transporter family protein | 0.0599 | 0.2961 | 0.3463 |
Loa Loa (eye worm) | hypothetical protein | 0.0599 | 0.2961 | 0.2961 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0105 | 0.0446 | 0.36 |
Echinococcus multilocularis | aurora kinase A | 0.0063 | 0.0232 | 0.0532 |
Loa Loa (eye worm) | hypothetical protein | 0.0599 | 0.2961 | 0.2961 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0087 | 0.0354 | 0.7919 |
Echinococcus multilocularis | 0.0023 | 0.0027 | 0.0063 | |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0087 | 0.0354 | 0.7919 |
Loa Loa (eye worm) | hypothetical protein | 0.0599 | 0.2961 | 0.2961 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0052 | 0.0177 | 0.0207 |
Trypanosoma cruzi | peptidyl-prolyl cis-trans isomerase | 0.0035 | 0.0093 | 0.2085 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0105 | 0.0446 | 0.36 |
Echinococcus multilocularis | expressed protein | 0.0036 | 0.0097 | 0.0223 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0599 | 0.2961 | 0.3463 |
Brugia malayi | Neuronal acetylcholine receptor protein, alpha-2 chain precursor | 0.0287 | 0.1372 | 0.1605 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0105 | 0.0446 | 0.36 |
Loa Loa (eye worm) | hypothetical protein | 0.1696 | 0.8551 | 0.8551 |
Schistosoma mansoni | nAChR subunit (ShAR1-beta-like) | 0.0599 | 0.2961 | 1 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.002 | 0.0016 | 0.0277 |
Onchocerca volvulus | Rap guanine nucleotide exchange factor 1 homolog | 0.0196 | 0.0912 | 0.3015 |
Brugia malayi | Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 | 0.0036 | 0.0097 | 0.0114 |
Loa Loa (eye worm) | CAMK/PIM protein kinase | 0.0174 | 0.0797 | 0.0797 |
Loa Loa (eye worm) | hypothetical protein | 0.0312 | 0.1502 | 0.1502 |
Onchocerca volvulus | Telomerase reverse transcriptase homolog | 0.0302 | 0.1453 | 0.486 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0032 | 0.0076 | 0.0258 |
Entamoeba histolytica | protein kinase, putative | 0.0098 | 0.0412 | 0.2669 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0047 | 0.0151 | 0.3381 |
Echinococcus multilocularis | gamma aminobutyric acid receptor subunit | 0.0287 | 0.1372 | 0.3146 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0047 | 0.0152 | 0.3398 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.002 | 0.0016 | 0.0018 |
Onchocerca volvulus | 0.0287 | 0.1372 | 0.4584 | |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0087 | 0.0354 | 0.7919 |
Loa Loa (eye worm) | CMGC/DYRK/DYRK1 protein kinase | 0.0098 | 0.0412 | 0.0412 |
Loa Loa (eye worm) | hypothetical protein | 0.0129 | 0.0568 | 0.0568 |
Leishmania major | DNA polymerase kappa, putative | 0.0065 | 0.0243 | 0.544 |
Echinococcus granulosus | nAChR subunit | 0.0312 | 0.1502 | 0.5071 |
Plasmodium falciparum | telomerase reverse transcriptase | 0.0083 | 0.0333 | 0.5866 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0087 | 0.0354 | 0.7919 |
Echinococcus multilocularis | geminin | 0.0367 | 0.178 | 0.4082 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.002 | 0.0016 | 0.0036 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.0599 | 0.2961 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0087 | 0.0354 | 0.7919 |
Mycobacterium tuberculosis | Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) | 0.0297 | 0.1427 | 1 |
Brugia malayi | acetylcholine receptor protein, alpha-like chain, putative | 0.0599 | 0.2961 | 0.3463 |
Entamoeba histolytica | Flap nuclease, putative | 0.0028 | 0.0057 | 0.0276 |
Loa Loa (eye worm) | hypothetical protein | 0.0599 | 0.2961 | 0.2961 |
Brugia malayi | serine/threonine-protein kinase 6 | 0.0063 | 0.0232 | 0.0271 |
Trypanosoma cruzi | flap endonuclease-1 (FEN-1), putative | 0.0028 | 0.0057 | 0.127 |
Entamoeba histolytica | serine/threonine protein kinase 6, putative | 0.0063 | 0.0232 | 0.1457 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0599 | 0.2961 | 0.3463 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0105 | 0.0446 | 0.36 |
Onchocerca volvulus | 0.0599 | 0.2961 | 1 | |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.002 | 0.0016 | 0.0352 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.002 | 0.0016 | 0.0271 |
Loa Loa (eye worm) | hypothetical protein | 0.0312 | 0.1502 | 0.1502 |
Schistosoma mansoni | acetylcholine receptor subunit beta | 0.0287 | 0.1372 | 0.4634 |
Loa Loa (eye worm) | hypothetical protein | 0.0599 | 0.2961 | 0.2961 |
Trypanosoma cruzi | DNA damage repair protein, putative | 0.0018 | 0.0004 | 0.0083 |
Echinococcus granulosus | nicotinic acetylcholine receptor beta 1 subunit | 0.0599 | 0.2961 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0312 | 0.1502 | 0.1502 |
Echinococcus granulosus | nicotinic acetylcholine receptor subunit type | 0.0599 | 0.2961 | 1 |
Leishmania major | UDP-galactopyranose mutase | 0.0023 | 0.0027 | 0.0611 |
Loa Loa (eye worm) | Pin1-type peptidyl-prolyl cis-trans isomerase | 0.0036 | 0.0097 | 0.0097 |
Echinococcus multilocularis | serine:threonine protein kinase 12 B | 0.0063 | 0.0232 | 0.0532 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0027 | 0.0027 |
Mycobacterium ulcerans | monoamine oxidase | 0.0023 | 0.0027 | 0.0153 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0032 | 0.0076 | 0.0258 |
Loa Loa (eye worm) | hypothetical protein | 0.0129 | 0.0568 | 0.0568 |
Echinococcus granulosus | neuronal acetylcholine receptor subunit alpha 4 | 0.0599 | 0.2961 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.005 | 0.0166 | 0.056 |
Echinococcus multilocularis | protoporphyrinogen oxidase | 0.0023 | 0.0027 | 0.0063 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0046 | 0.0145 | 0.3242 |
Leishmania major | DNA polymerase eta, putative | 0.0046 | 0.0145 | 0.3242 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0032 | 0.0076 | 0.0258 |
Brugia malayi | serine/threonine-protein kinase plk-2 | 0.0105 | 0.0446 | 0.0522 |
Entamoeba histolytica | chitinase, putative | 0.0081 | 0.0326 | 0.2085 |
Echinococcus granulosus | glycine receptor subunit alpha 1 | 0.0599 | 0.2961 | 1 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.0058 | 0.0206 | 0.0206 |
Giardia lamblia | Kinase, PLK | 0.0105 | 0.0446 | 1 |
Echinococcus multilocularis | Hepatocellular carcinoma associated antigen 59 | 0.0129 | 0.0568 | 0.1303 |
Schistosoma mansoni | tsg101-related | 0.0063 | 0.0233 | 0.0787 |
Trypanosoma cruzi | UDP-galactopyranose mutase | 0.0023 | 0.0027 | 0.0611 |
Trypanosoma brucei | chrX additional, unordered contigs | 0.0018 | 0.0004 | 0.0083 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.002 | 0.0016 | 0.0078 |
Echinococcus multilocularis | acetylcholine receptor subunit beta 1 | 0.0599 | 0.2961 | 0.679 |
Loa Loa (eye worm) | flap endonuclease-1 | 0.0028 | 0.0057 | 0.0057 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0085 | 0.0347 | 0.7781 |
Leishmania major | telomerase reverse transcriptase, putative | 0.0083 | 0.0333 | 0.7467 |
Echinococcus multilocularis | glycine receptor subunit beta | 0.0599 | 0.2961 | 0.679 |
Brugia malayi | polk-prov protein | 0.0047 | 0.0151 | 0.0177 |
Giardia lamblia | Telomerase catalytic subunit | 0.0083 | 0.0333 | 0.7445 |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.0058 | 0.0206 | 0.0697 |
Trichomonas vaginalis | AGC family protein kinase | 0.0063 | 0.0232 | 0.1809 |
Loa Loa (eye worm) | hypothetical protein | 0.0599 | 0.2961 | 0.2961 |
Onchocerca volvulus | 0.0129 | 0.0568 | 0.1844 | |
Loa Loa (eye worm) | hypothetical protein | 0.1409 | 0.7091 | 0.7091 |
Trypanosoma cruzi | CMGC/DYRK protein kinase, putative | 0.0098 | 0.0412 | 0.9235 |
Trypanosoma brucei | unspecified product | 0.004 | 0.0115 | 0.2579 |
Echinococcus granulosus | tumor susceptibility gene 101 protein | 0.0076 | 0.0298 | 0.1005 |
Leishmania major | DNA polymerase eta, putative | 0.0085 | 0.0347 | 0.7781 |
Loa Loa (eye worm) | hypothetical protein | 0.0599 | 0.2961 | 0.2961 |
Trypanosoma cruzi | telomerase reverse transcriptase, putative | 0.0083 | 0.0333 | 0.7467 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0151 | 0.0151 |
Brugia malayi | nicotinic acetylcholine receptor beta-1 chain precursor | 0.0599 | 0.2961 | 0.3463 |
Echinococcus granulosus | indoleamine 23 dioxygenase 2 | 0.0595 | 0.2941 | 0.9932 |
Loa Loa (eye worm) | hypothetical protein | 0.0599 | 0.2961 | 0.2961 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.0087 | 0.0354 | 0.2824 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.002 | 0.0016 | 0.0352 |
Loa Loa (eye worm) | LGC-31 protein | 0.0599 | 0.2961 | 0.2961 |
Brugia malayi | amine oxidase, flavin-containing family protein | 0.0023 | 0.0027 | 0.0032 |
Mycobacterium ulcerans | chitinase/cellulase | 0.0069 | 0.0265 | 0.1697 |
Echinococcus granulosus | Cys loop ligand gated ion channel subunit | 0.0287 | 0.1372 | 0.4634 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0087 | 0.0354 | 0.7919 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.005 | 0.0166 | 0.038 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0174 | 0.0797 | 0.2692 |
Echinococcus granulosus | glycine receptor subunit beta | 0.0599 | 0.2961 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0599 | 0.2961 | 0.2961 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.002 | 0.0016 | 0.011 |
Schistosoma mansoni | nicotinic acetylcholine receptor alpha | 0.0312 | 0.1502 | 0.5071 |
Mycobacterium ulcerans | flavin-containing monoamine oxidase AofH | 0.032 | 0.1542 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0599 | 0.2961 | 0.2961 |
Trichomonas vaginalis | AGC family protein kinase | 0.0063 | 0.0232 | 0.1809 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.002 | 0.0016 | 0.0026 |
Entamoeba histolytica | tumor susceptibility gene 101 protein, putative | 0.0051 | 0.0174 | 0.1068 |
Brugia malayi | serine/threonine protein kinase 6 | 0.0063 | 0.0232 | 0.0271 |
Brugia malayi | hypothetical protein | 0.0287 | 0.1372 | 0.1605 |
Leishmania major | chitinase | 0.0081 | 0.0326 | 0.7292 |
Schistosoma mansoni | nAChR subunit | 0.0599 | 0.2961 | 1 |
Toxoplasma gondii | BRCA1 C Terminus (BRCT) domain-containing protein | 0.0025 | 0.004 | 0.0708 |
Echinococcus multilocularis | indoleamine 2,3 dioxygenase 2 | 0.0595 | 0.2941 | 0.6744 |
Echinococcus multilocularis | Cys loop ligand gated ion channel subunit | 0.0287 | 0.1372 | 0.3146 |
Brugia malayi | glutamate-gated chloride channel alpha3A subunit, putative | 0.0312 | 0.1502 | 0.1756 |
Schistosoma mansoni | tsg101-related | 0.0051 | 0.0174 | 0.0589 |
Brugia malayi | Hypothetical glycine receptor like protein T20B12.9 in chromosome III | 0.0599 | 0.2961 | 0.3463 |
Brugia malayi | gamma-aminobutyric-acid receptor beta subunit precursor | 0.1696 | 0.8551 | 1 |
Echinococcus granulosus | nicotinic acetylcholine receptor alpha subunit | 0.0599 | 0.2961 | 1 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.002 | 0.0016 | 0.0352 |
Plasmodium falciparum | conserved protein, unknown function | 0.0129 | 0.0568 | 1 |
Brugia malayi | Flap endonuclease-1 | 0.0028 | 0.0057 | 0.0066 |
Onchocerca volvulus | Serine\/threonine protein kinase homolog | 0.0174 | 0.0797 | 0.2624 |
Onchocerca volvulus | 0.0599 | 0.2961 | 1 | |
Echinococcus granulosus | dna polymerase eta | 0.0085 | 0.0347 | 0.1173 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0018 | 0.0004 | 0.0083 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.0087 | 0.0354 | 0.2824 |
Loa Loa (eye worm) | cuticular endochitinase | 0.0081 | 0.0326 | 0.0326 |
Brugia malayi | endochitinase | 0.0081 | 0.0326 | 0.0381 |
Loa Loa (eye worm) | hypothetical protein | 0.0287 | 0.1372 | 0.1372 |
Trypanosoma brucei | polo-like protein kinase | 0.0105 | 0.0446 | 1 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0058 | 0.0206 | 0.1446 |
Trichomonas vaginalis | set domain proteins, putative | 0.0255 | 0.1212 | 1 |
Brugia malayi | Cation transporter family protein | 0.0599 | 0.2961 | 0.3463 |
Echinococcus granulosus | dual specificity | 0.0098 | 0.0412 | 0.1392 |
Giardia lamblia | Flap structure-specific endonuclease | 0.0028 | 0.0057 | 0.1197 |
Entamoeba histolytica | hypothetical protein | 0.0078 | 0.0309 | 0.1974 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0032 | 0.0076 | 0.1343 |
Schistosoma mansoni | nAChR subunit | 0.0599 | 0.2961 | 1 |
Trypanosoma cruzi | CMGC/DYRK protein kinase, putative | 0.0098 | 0.0412 | 0.9235 |
Brugia malayi | Pre-SET motif family protein | 0.0032 | 0.0076 | 0.0089 |
Loa Loa (eye worm) | AUR protein kinase | 0.0063 | 0.0232 | 0.0232 |
Echinococcus multilocularis | Cys loop ligand gated ion channel subunit | 0.0599 | 0.2961 | 0.679 |
Brugia malayi | serine/threonine kinase 12 | 0.0063 | 0.0232 | 0.0271 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Inhibition (functional) | = 26 % | DNDI: Inhibition of Human African Trypanosomiasis, SBRI 427, in vitro at 2 ug.mL-1 | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.