Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.003 | 0.0254 | 0.5844 |
Brugia malayi | beta-tubulin, identical | 0.0014 | 0.0042 | 0.0056 |
Trypanosoma cruzi | pyruvate kinase 2, putative | 0.003 | 0.0262 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0136 | 0.0287 |
Echinococcus multilocularis | zinc finger protein | 0.0017 | 0.0078 | 0.0078 |
Schistosoma mansoni | tar DNA-binding protein | 0.0055 | 0.0602 | 0.0693 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0332 | 0.0701 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0088 | 0.1065 | 0.2164 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0042 | 0.0425 | 1 |
Echinococcus multilocularis | aryl hydrocarbon receptor | 0.0026 | 0.0197 | 0.0197 |
Schistosoma mansoni | hypothetical protein | 0.0028 | 0.0231 | 0.0255 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0354 | 0.0749 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0031 | 0.0278 | 0.3159 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0015 | 0.0048 | 0.0048 |
Leishmania major | pyruvate kinase | 0.003 | 0.0262 | 0.6032 |
Onchocerca volvulus | 0.0017 | 0.0075 | 0.016 | |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0425 | 0.0898 |
Plasmodium vivax | tubulin beta chain, putative | 0.0014 | 0.0042 | 0.1034 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0031 | 0.0274 | 0.0323 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0031 | 0.0278 | 0.6421 |
Leishmania major | beta tubulin | 0.0014 | 0.0042 | 0.0664 |
Schistosoma mansoni | lamin | 0.0023 | 0.0167 | 0.018 |
Leishmania major | beta tubulin | 0.0014 | 0.0042 | 0.0664 |
Echinococcus multilocularis | tubulin, beta 4A class IVa | 0.0014 | 0.0042 | 0.0042 |
Trypanosoma cruzi | ISWI complex protein | 0.0013 | 0.0027 | 0.0507 |
Schistosoma mansoni | hypothetical protein | 0.0028 | 0.0231 | 0.0255 |
Schistosoma mansoni | zinc finger protein | 0.0017 | 0.0078 | 0.0075 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0028 | 0.0231 | 0.0487 |
Loa Loa (eye worm) | BEN-1 protein | 0.0014 | 0.0042 | 0.0089 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0042 | 0.0425 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0679 | 0.1435 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0031 | 0.0274 | 0.0274 |
Leishmania major | beta tubulin | 0.0014 | 0.0042 | 0.0664 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0231 | 0.0487 |
Loa Loa (eye worm) | intermediate filament protein | 0.0023 | 0.0167 | 0.0353 |
Mycobacterium ulcerans | hypothetical protein | 0.0042 | 0.0425 | 0.492 |
Echinococcus multilocularis | pyruvate kinase | 0.003 | 0.0262 | 0.0262 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0015 | 0.0031 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0028 | 0.0231 | 0.0231 |
Onchocerca volvulus | 0.0023 | 0.0167 | 0.0403 | |
Echinococcus granulosus | Tubulin beta 2C chain | 0.0014 | 0.0042 | 0.0049 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0028 | 0.0231 | 0.0445 |
Brugia malayi | hypoxia-induced factor 1 | 0.0304 | 0.4042 | 0.8298 |
Echinococcus granulosus | pyruvate kinase | 0.0016 | 0.0059 | 0.0069 |
Toxoplasma gondii | pyruvate kinase PyKII | 0.0016 | 0.0059 | 0.1779 |
Echinococcus multilocularis | musashi | 0.0023 | 0.0167 | 0.0167 |
Loa Loa (eye worm) | RNA binding protein | 0.0055 | 0.0602 | 0.1273 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.002 | 0.0114 | 0.0134 |
Schistosoma mansoni | jun-related protein | 0.0296 | 0.3927 | 0.4618 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription factor | 0.0364 | 0.4868 | 0.5736 |
Echinococcus granulosus | MAM | 0.0017 | 0.0075 | 0.0089 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0042 | 0.0425 | 0.492 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0052 | 0.0558 | 0.0558 |
Leishmania major | beta tubulin | 0.0014 | 0.0042 | 0.0664 |
Leishmania major | hypothetical protein, conserved | 0.0013 | 0.0027 | 0.0306 |
Leishmania major | beta tubulin | 0.0014 | 0.0042 | 0.0664 |
Echinococcus granulosus | single minded 2 | 0.0073 | 0.0848 | 0.0999 |
Trichomonas vaginalis | pyruvate kinase, putative | 0.003 | 0.0262 | 1 |
Echinococcus granulosus | GPCR family 2 | 0.0028 | 0.0231 | 0.0272 |
Leishmania major | beta tubulin | 0.0014 | 0.0042 | 0.0664 |
Trichomonas vaginalis | tubulin, putative | 0.0014 | 0.0042 | 0.1101 |
Trypanosoma brucei | beta tubulin | 0.0014 | 0.0042 | 0.1101 |
Schistosoma mansoni | tar DNA-binding protein | 0.0055 | 0.0602 | 0.0693 |
Schistosoma mansoni | tubulin subunit beta | 0.0014 | 0.0042 | 0.0032 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.003 | 0.0254 | 0.5844 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0042 | 0.0425 | 0.492 |
Trichomonas vaginalis | adenylate and guanylate cyclases, putative | 0.0026 | 0.0197 | 0.7361 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0031 | 0.0278 | 1 |
Onchocerca volvulus | 0.0026 | 0.0197 | 0.0482 | |
Onchocerca volvulus | 0.0286 | 0.3789 | 1 | |
Plasmodium vivax | pyruvate kinase 2, putative | 0.0016 | 0.0059 | 0.1671 |
Trypanosoma cruzi | STE group serine/threonine-protein kinase, putative | 0.0026 | 0.0197 | 0.7361 |
Schistosoma mansoni | tar DNA-binding protein | 0.0055 | 0.0602 | 0.0693 |
Trichomonas vaginalis | tubulin epsilon chain, putative | 0.0014 | 0.0042 | 0.1101 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0425 | 0.0898 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0042 | 0.0425 | 1 |
Brugia malayi | Tubulin beta-1 chain | 0.0014 | 0.0042 | 0.0056 |
Schistosoma mansoni | hypothetical protein | 0.006 | 0.0679 | 0.0784 |
Echinococcus multilocularis | GPCR, family 2 | 0.0028 | 0.0231 | 0.0231 |
Brugia malayi | Protein kinase domain containing protein | 0.014 | 0.1782 | 0.3641 |
Loa Loa (eye worm) | TAR-binding protein | 0.0055 | 0.0602 | 0.1273 |
Onchocerca volvulus | 0.0017 | 0.0075 | 0.016 | |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0045 | 0.0464 | 0.053 |
Schistosoma mansoni | tubulin subunit beta | 0.0014 | 0.0042 | 0.0032 |
Leishmania major | beta tubulin | 0.0014 | 0.0042 | 0.0664 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0028 | 0.0231 | 0.0445 |
Trichomonas vaginalis | tubulin gamma chain, putative | 0.0014 | 0.0042 | 0.1101 |
Echinococcus granulosus | jun protein | 0.0364 | 0.4868 | 0.5736 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0015 | 0.0048 | 0.004 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0425 | 0.0898 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0042 | 0.0425 | 1 |
Onchocerca volvulus | 0.0045 | 0.0464 | 0.1189 | |
Trypanosoma cruzi | pyruvate kinase 2, putative | 0.003 | 0.0262 | 1 |
Echinococcus multilocularis | tubulin subunit beta | 0.0014 | 0.0042 | 0.0042 |
Giardia lamblia | Pyruvate kinase | 0.0016 | 0.0059 | 0.0762 |
Mycobacterium ulcerans | putative regulatory protein | 0.0073 | 0.0848 | 1 |
Echinococcus multilocularis | beta tubulin | 0.0014 | 0.0042 | 0.0042 |
Mycobacterium leprae | Probable pyruvate kinase PykA | 0.003 | 0.0262 | 0.6032 |
Echinococcus granulosus | Tubulin beta 2C chain | 0.0014 | 0.0042 | 0.0049 |
Echinococcus multilocularis | transfer RNA-Lys | 0.0073 | 0.0848 | 0.0848 |
Mycobacterium leprae | Possible regulatory protein | 0.0026 | 0.0197 | 0.444 |
Schistosoma mansoni | zinc finger protein | 0.0013 | 0.0027 | 0.0015 |
Echinococcus granulosus | pyruvate kinase | 0.0016 | 0.0059 | 0.0069 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0031 | 0.0278 | 1 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0023 | 0.0167 | 0.0353 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0015 | 0.0048 | 0.0057 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription factor | 0.0364 | 0.4868 | 0.4868 |
Loa Loa (eye worm) | hypothetical protein | 0.0061 | 0.069 | 0.1459 |
Schistosoma mansoni | tar DNA-binding protein | 0.0055 | 0.0602 | 0.0693 |
Brugia malayi | Bromodomain containing protein | 0.0033 | 0.0302 | 0.0593 |
Schistosoma mansoni | single-minded | 0.0098 | 0.1201 | 0.14 |
Brugia malayi | Bromodomain containing protein | 0.0065 | 0.0741 | 0.1497 |
Echinococcus granulosus | microtubule associated protein 2 | 0.0626 | 0.8487 | 1 |
Echinococcus multilocularis | tar DNA binding protein | 0.0055 | 0.0602 | 0.0602 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0026 | 0.0197 | 0.7361 |
Onchocerca volvulus | 0.0073 | 0.0848 | 0.2208 | |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0075 | 0.0071 |
Loa Loa (eye worm) | oxidoreductase | 0.0012 | 0.0015 | 0.0031 |
Echinococcus granulosus | beta tubulin | 0.0014 | 0.0042 | 0.0049 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0626 | 0.8487 | 0.8487 |
Brugia malayi | bZIP transcription factor family protein | 0.0364 | 0.4868 | 1 |
Leishmania major | beta tubulin | 0.0014 | 0.0042 | 0.0664 |
Echinococcus multilocularis | Tubulin beta 2C chain | 0.0014 | 0.0042 | 0.0042 |
Echinococcus multilocularis | jun protein | 0.0364 | 0.4868 | 0.4868 |
Brugia malayi | AMP-binding enzyme family protein | 0.0042 | 0.0425 | 0.0845 |
Trypanosoma cruzi | PAS-domain containing phosphoglycerate kinase, putative | 0.0026 | 0.0197 | 0.7361 |
Schistosoma mansoni | hypothetical protein | 0.0296 | 0.3927 | 0.4618 |
Mycobacterium ulcerans | pyruvate kinase | 0.003 | 0.0262 | 0.2968 |
Schistosoma mansoni | tubulin subunit beta | 0.0014 | 0.0042 | 0.0032 |
Toxoplasma gondii | beta-tubulin, putative | 0.0014 | 0.0042 | 0.1101 |
Onchocerca volvulus | Pyruvate kinase homolog | 0.003 | 0.0262 | 0.0655 |
Echinococcus multilocularis | beta tubulin | 0.0014 | 0.0042 | 0.0042 |
Loa Loa (eye worm) | hypothetical protein | 0.0354 | 0.4731 | 1 |
Leishmania major | beta tubulin | 0.0014 | 0.0042 | 0.0664 |
Leishmania major | beta tubulin | 0.0014 | 0.0042 | 0.0664 |
Loa Loa (eye worm) | bromodomain containing protein | 0.0015 | 0.0056 | 0.0118 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.002 | 0.0114 | 0.0114 |
Onchocerca volvulus | 0.0023 | 0.0167 | 0.0403 | |
Trypanosoma brucei | beta tubulin | 0.0014 | 0.0042 | 0.1101 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0015 | 0.0031 |
Loa Loa (eye worm) | pyruvate kinase | 0.003 | 0.0262 | 0.0554 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.003 | 0.0254 | 0.5844 |
Trypanosoma cruzi | PAS-domain containing phosphoglycerate kinase, putative | 0.0026 | 0.0197 | 0.7361 |
Echinococcus multilocularis | pyruvate kinase | 0.0016 | 0.0059 | 0.0059 |
Loa Loa (eye worm) | BEN-1 protein | 0.0014 | 0.0042 | 0.0089 |
Trypanosoma cruzi | ISWI complex protein | 0.0013 | 0.0027 | 0.0507 |
Schistosoma mansoni | tubulin subunit beta | 0.0014 | 0.0042 | 0.0032 |
Leishmania major | beta tubulin | 0.0014 | 0.0042 | 0.0664 |
Echinococcus granulosus | tubulin beta 4A class IVa | 0.0014 | 0.0042 | 0.0049 |
Trichomonas vaginalis | tubulin alpha chain, putative | 0.0014 | 0.0042 | 0.1101 |
Leishmania major | beta tubulin | 0.0014 | 0.0042 | 0.0664 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0042 | 0.0425 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0278 | 0.0588 |
Trichomonas vaginalis | guanylate cyclase, putative | 0.0026 | 0.0197 | 0.7361 |
Echinococcus multilocularis | Tubulin beta 2C chain | 0.0014 | 0.0042 | 0.0042 |
Leishmania major | protein kinase, putative | 0.0026 | 0.0197 | 0.444 |
Schistosoma mansoni | hypothetical protein | 0.0013 | 0.0027 | 0.0015 |
Trypanosoma brucei | beta tubulin | 0.0014 | 0.0042 | 0.1101 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0088 | 0.1065 | 0.2164 |
Trypanosoma brucei | beta tubulin | 0.0014 | 0.0042 | 0.1101 |
Brugia malayi | hypothetical protein | 0.033 | 0.4395 | 0.9024 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0262 | 0.0554 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0026 | 0.0197 | 0.7361 |
Echinococcus multilocularis | Tubulin beta 2C chain | 0.0014 | 0.0042 | 0.0042 |
Giardia lamblia | Pyruvate kinase | 0.003 | 0.0262 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0161 | 0.034 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0028 | 0.0231 | 0.0231 |
Trichomonas vaginalis | adenylate and guanylate cyclases, putative | 0.0026 | 0.0197 | 0.7361 |
Loa Loa (eye worm) | tubulin beta-1 chain | 0.0014 | 0.0042 | 0.0089 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.006 | 0.0679 | 0.1368 |
Trypanosoma brucei | pyruvate kinase 1, putative | 0.003 | 0.0262 | 1 |
Plasmodium vivax | pyruvate kinase, putative | 0.003 | 0.0262 | 0.9393 |
Onchocerca volvulus | Pyruvate kinase homolog | 0.003 | 0.0262 | 0.0655 |
Loa Loa (eye worm) | tubulin beta-2A chain | 0.0014 | 0.0042 | 0.0089 |
Leishmania major | PAS-domain containing phosphoglycerate kinase, putative | 0.0026 | 0.0197 | 0.444 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0055 | 0.0602 | 0.121 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0023 | 0.0167 | 0.0313 |
Echinococcus multilocularis | pyruvate kinase | 0.0024 | 0.0174 | 0.0174 |
Loa Loa (eye worm) | tubulin beta chain | 0.0014 | 0.0042 | 0.0089 |
Echinococcus multilocularis | tumor protein p63 | 0.0307 | 0.4076 | 0.4076 |
Toxoplasma gondii | pyruvate kinase PyK1 | 0.003 | 0.0262 | 1 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0088 | 0.1065 | 0.2251 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0031 | 0.0278 | 1 |
Plasmodium falciparum | tubulin beta chain | 0.0014 | 0.0042 | 0.1034 |
Loa Loa (eye worm) | hypoxia-induced factor 1 | 0.0304 | 0.4042 | 0.8545 |
Trypanosoma brucei | ISWI complex protein | 0.0013 | 0.0027 | 0.0507 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0278 | 0.0588 |
Brugia malayi | bHLH-PAS transcription factor | 0.0073 | 0.0848 | 0.1717 |
Trypanosoma brucei | pyruvate kinase 1 | 0.003 | 0.0262 | 1 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0042 | 0.0425 | 0.492 |
Leishmania major | beta tubulin | 0.0014 | 0.0042 | 0.0664 |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.0012 | 0.0015 | 0.0031 |
Brugia malayi | PHD-finger family protein | 0.0022 | 0.0142 | 0.0263 |
Trypanosoma cruzi | STE/STE11 serine/threonine-protein kinase, putative | 0.0026 | 0.0197 | 0.7361 |
Echinococcus granulosus | tumor protein p63 | 0.0307 | 0.4076 | 0.4803 |
Toxoplasma gondii | beta-1 tubulin, putative | 0.0014 | 0.0042 | 0.1101 |
Chlamydia trachomatis | pyruvate kinase | 0.003 | 0.0262 | 0.8034 |
Brugia malayi | intermediate filament protein | 0.0023 | 0.0167 | 0.0313 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0075 | 0.0159 |
Echinococcus multilocularis | lamin dm0 | 0.0023 | 0.0167 | 0.0167 |
Echinococcus multilocularis | lamin | 0.0023 | 0.0167 | 0.0167 |
Echinococcus granulosus | beta tubulin | 0.0014 | 0.0042 | 0.0049 |
Toxoplasma gondii | beta tubulin | 0.0014 | 0.0042 | 0.1101 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0464 | 0.098 |
Leishmania major | beta tubulin | 0.0014 | 0.0042 | 0.0664 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0197 | 0.0416 |
Echinococcus multilocularis | acetyl coenzyme A synthetase, cytoplasmic | 0.0012 | 0.0015 | 0.0015 |
Echinococcus multilocularis | tubulin beta 1 chain | 0.0014 | 0.0042 | 0.0042 |
Trypanosoma cruzi | STE/STE11 serine/threonine-protein kinase, putative | 0.0026 | 0.0197 | 0.7361 |
Echinococcus multilocularis | pyruvate kinase | 0.0016 | 0.0059 | 0.0059 |
Echinococcus granulosus | pyruvate kinase | 0.003 | 0.0262 | 0.0309 |
Echinococcus multilocularis | Tubulin beta 2C chain | 0.0014 | 0.0042 | 0.0042 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0042 | 0.0425 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0028 | 0.0231 | 0.0255 |
Trypanosoma cruzi | STE group serine/threonine-protein kinase, putative | 0.0026 | 0.0197 | 0.7361 |
Leishmania major | beta tubulin | 0.0014 | 0.0042 | 0.0664 |
Onchocerca volvulus | 0.0042 | 0.0425 | 0.1086 | |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0052 | 0.0558 | 0.0658 |
Trichomonas vaginalis | pyruvate kinase, putative | 0.003 | 0.0262 | 1 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0018 | 0.0091 | 0.0193 |
Echinococcus granulosus | Aryl hydrocarbon receptor nuclear | 0.0026 | 0.0197 | 0.0232 |
Loa Loa (eye worm) | hypothetical protein | 0.0088 | 0.1065 | 0.2251 |
Trypanosoma cruzi | beta tubulin, putative | 0.0014 | 0.0042 | 0.1101 |
Brugia malayi | TAR-binding protein | 0.0055 | 0.0602 | 0.121 |
Onchocerca volvulus | Pyruvate kinase homolog | 0.003 | 0.0262 | 0.0655 |
Schistosoma mansoni | hypothetical protein | 0.0028 | 0.0231 | 0.0255 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0278 | 0.0588 |
Echinococcus multilocularis | methyl CpG binding domain protein 2 | 0.0015 | 0.0048 | 0.0048 |
Echinococcus granulosus | Tubulin beta 2C chain | 0.0014 | 0.0042 | 0.0049 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.003 | 0.0254 | 0.5844 |
Loa Loa (eye worm) | pyruvate kinase-PB | 0.0021 | 0.0136 | 0.0287 |
Echinococcus granulosus | tar DNA binding protein | 0.0055 | 0.0602 | 0.0709 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0075 | 0.0071 |
Echinococcus multilocularis | pyruvate kinase | 0.0016 | 0.0059 | 0.0059 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0075 | 0.0159 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0042 | 0.0425 | 1 |
Echinococcus multilocularis | Aryl hydrocarbon receptor nuclear | 0.0026 | 0.0197 | 0.0197 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0028 | 0.0231 | 0.0272 |
Echinococcus granulosus | lamin | 0.0023 | 0.0167 | 0.0197 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0042 | 0.0425 | 0.492 |
Trichomonas vaginalis | guanylate cyclase, putative | 0.0026 | 0.0197 | 0.7361 |
Schistosoma mansoni | aryl hydrocarbon receptor | 0.0098 | 0.1201 | 0.14 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0042 | 0.0425 | 1 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0055 | 0.0602 | 0.1273 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0048 | 0.0102 |
Echinococcus granulosus | Tubulin beta 2C chain | 0.0014 | 0.0042 | 0.0049 |
Leishmania major | beta tubulin | 0.0014 | 0.0042 | 0.0664 |
Plasmodium falciparum | pyruvate kinase 2 | 0.0016 | 0.0059 | 0.1671 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0013 | 0.0017 | 0.0036 |
Loa Loa (eye worm) | hypothetical protein | 0.0123 | 0.1542 | 0.3259 |
Leishmania major | beta tubulin | 0.0014 | 0.0042 | 0.0664 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0626 | 0.8487 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0026 | 0.0197 | 0.7361 |
Trichomonas vaginalis | adenylate and guanylate cyclases, putative | 0.0026 | 0.0197 | 0.7361 |
Entamoeba histolytica | tubulin family protein | 0.0014 | 0.0042 | 0.0664 |
Entamoeba histolytica | tubulin family protein | 0.0014 | 0.0042 | 0.0664 |
Schistosoma mansoni | lamin | 0.0023 | 0.0167 | 0.018 |
Loa Loa (eye worm) | pyruvate kinase | 0.003 | 0.0262 | 0.0554 |
Echinococcus granulosus | pyruvate kinase | 0.003 | 0.0262 | 0.0309 |
Brugia malayi | hypothetical protein | 0.0017 | 0.0075 | 0.0125 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0042 | 0.0425 | 0.492 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0013 | 0.0017 | 0.0005 |
Leishmania major | pyruvate kinase | 0.003 | 0.0262 | 0.6032 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.002 | 0.0114 | 0.0117 |
Schistosoma mansoni | pyruvate kinase | 0.0016 | 0.0059 | 0.0052 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0015 | 0.0048 | 0.004 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0042 | 0.0425 | 1 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0042 | 0.0425 | 1 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0015 | 0.0048 | 0.004 |
Loa Loa (eye worm) | aryl Hydrocarbon receptor Associated protein family member | 0.0026 | 0.0197 | 0.0416 |
Brugia malayi | Pyruvate kinase, M2 isozyme | 0.003 | 0.0262 | 0.051 |
Trichomonas vaginalis | tubulin beta chain, putative | 0.0014 | 0.0042 | 0.1101 |
Brugia malayi | Pyruvate kinase, muscle isozyme | 0.003 | 0.0262 | 0.051 |
Plasmodium falciparum | pyruvate kinase | 0.003 | 0.0262 | 0.9393 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0042 | 0.0425 | 0.492 |
Echinococcus multilocularis | pyruvate kinase | 0.003 | 0.0262 | 0.0262 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0015 | 0.0048 | 0.004 |
Echinococcus granulosus | intermediate filament protein | 0.0023 | 0.0167 | 0.0197 |
Loa Loa (eye worm) | beta-tubulin | 0.0014 | 0.0042 | 0.0089 |
Brugia malayi | AMP-binding enzyme family protein | 0.0042 | 0.0425 | 0.0845 |
Echinococcus granulosus | acetyl coenzyme A synthetase cytoplasmic | 0.0012 | 0.0015 | 0.0017 |
Brugia malayi | RNA binding protein | 0.0055 | 0.0602 | 0.121 |
Leishmania major | beta tubulin | 0.0014 | 0.0042 | 0.0664 |
Schistosoma mansoni | intermediate filament proteins | 0.0023 | 0.0167 | 0.018 |
Brugia malayi | AMP-binding enzyme family protein | 0.0042 | 0.0425 | 0.0845 |
Mycobacterium tuberculosis | Probable pyruvate kinase PykA | 0.003 | 0.0262 | 0.6032 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0278 | 0.0588 |
Echinococcus multilocularis | Tubulin beta 2C chain | 0.0014 | 0.0042 | 0.0042 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0042 | 0.0425 | 0.492 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0303 | 0.0641 |
Leishmania major | protein kinase, putative | 0.0026 | 0.0197 | 0.444 |
Trichomonas vaginalis | adenylate cyclase, type VII, putative | 0.0026 | 0.0197 | 0.7361 |
Schistosoma mansoni | pyruvate kinase | 0.003 | 0.0262 | 0.0292 |
Echinococcus granulosus | aryl hydrocarbon receptor | 0.0026 | 0.0197 | 0.0232 |
Echinococcus multilocularis | MAM | 0.0017 | 0.0075 | 0.0075 |
Loa Loa (eye worm) | tubulin beta-4 chain | 0.0014 | 0.0042 | 0.0089 |
Trichomonas vaginalis | tubulin epsilon chain, putative | 0.0014 | 0.0042 | 0.1101 |
Schistosoma mansoni | tubulin subunit beta | 0.0014 | 0.0042 | 0.0032 |
Echinococcus granulosus | pyruvate kinase | 0.0016 | 0.0059 | 0.0069 |
Echinococcus granulosus | Tubulin beta 2C chain | 0.0014 | 0.0042 | 0.0049 |
Echinococcus granulosus | tubulin beta 1 chain | 0.0014 | 0.0042 | 0.0049 |
Schistosoma mansoni | pyruvate kinase | 0.003 | 0.0262 | 0.0292 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0278 | 0.0588 |
Schistosoma mansoni | tubulin subunit beta | 0.0014 | 0.0042 | 0.0032 |
Trichomonas vaginalis | adenylate cyclase, putative | 0.0026 | 0.0197 | 0.7361 |
Trichomonas vaginalis | soluble guanylate cyclase gcy, putative | 0.0026 | 0.0197 | 0.7361 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0075 | 0.0159 |
Schistosoma mansoni | bromodomain containing protein | 0.0055 | 0.0601 | 0.0692 |
Echinococcus granulosus | lamin dm0 | 0.0023 | 0.0167 | 0.0197 |
Brugia malayi | PAS domain containing protein | 0.0098 | 0.1201 | 0.2443 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0167 | 0.0353 |
Echinococcus granulosus | zinc finger protein | 0.0017 | 0.0078 | 0.0092 |
Entamoeba histolytica | pyruvate kinase, putative | 0.0021 | 0.0136 | 0.2949 |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.0012 | 0.0015 | 0.0031 |
Loa Loa (eye worm) | pyruvate kinase | 0.003 | 0.0262 | 0.0554 |
Schistosoma mansoni | tar DNA-binding protein | 0.0055 | 0.0602 | 0.0693 |
Loa Loa (eye worm) | TK/ALK protein kinase | 0.014 | 0.1781 | 0.3766 |
Echinococcus granulosus | tubulin subunit beta | 0.0014 | 0.0042 | 0.0049 |
Brugia malayi | hypothetical protein | 0.0286 | 0.3789 | 0.7777 |
Schistosoma mansoni | hypothetical protein | 0.0018 | 0.0091 | 0.009 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0028 | 0.0231 | 0.0272 |
Echinococcus granulosus | methyl CpG binding domain protein 2 | 0.0015 | 0.0048 | 0.0057 |
Loa Loa (eye worm) | hypothetical protein | 0.033 | 0.4395 | 0.929 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (binding) | < 100 uM | Concentration required to reduce binding of fibrinogen to purified Fibrinogen Receptor by 50% using ELISA | ChEMBL. | 9207949 |
IC50 (binding) | < 100 uM | Concentration required to reduce binding of fibrinogen to purified Fibrinogen Receptor by 50% using ELISA | ChEMBL. | 9207949 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.