Detailed information for compound 1080853

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 435.542 | Formula: C23H25N5O2S
  • H donors: 3 H acceptors: 2 LogP: 4.23 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: S=C(NC(=O)c1ccccc1)Nc1cc2[nH]c(=O)cnc2cc1N(C1CCCCC1)C
  • InChi: 1S/C23H25N5O2S/c1-28(16-10-6-3-7-11-16)20-13-17-18(25-21(29)14-24-17)12-19(20)26-23(31)27-22(30)15-8-4-2-5-9-15/h2,4-5,8-9,12-14,16H,3,6-7,10-11H2,1H3,(H,25,29)(H2,26,27,30,31)
  • InChiKey: FTWIBUGWDLHHEM-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus GPCR family 2 0.0047 0.1008 0.0999
Mycobacterium ulcerans DNA polymerase IV 0.0038 0.0715 0.067
Echinococcus multilocularis beta LACTamase domain containing family member 0.0037 0.0676 0.0667
Loa Loa (eye worm) hypothetical protein 0.0038 0.0715 0.1009
Echinococcus granulosus muscleblind protein 0.0164 0.4752 0.4747
Schistosoma mansoni tar DNA-binding protein 0.0062 0.1493 0.2277
Echinococcus multilocularis GA binding protein alpha chain 0.0073 0.1824 0.1816
Schistosoma mansoni hypothetical protein 0.0047 0.1008 0.1538
Brugia malayi RNA binding protein 0.0062 0.1493 0.2124
Schistosoma mansoni terminal deoxycytidyl transferase 0.0038 0.0715 0.109
Toxoplasma gondii aldehyde dehydrogenase 0.0061 0.1449 1
Schistosoma mansoni tar DNA-binding protein 0.0062 0.1493 0.2277
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0023 0.0237 0.0361
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0715 1
Mycobacterium ulcerans lipase LipD 0.0037 0.0676 0.0181
Entamoeba histolytica hypothetical protein 0.0105 0.2861 1
Onchocerca volvulus 0.0242 0.7243 1
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0105 0.2861 0.2854
Brugia malayi beta-lactamase family protein 0.0037 0.0676 0.0954
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0038 0.0715 0.0705
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0149 0.4266 0.6098
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0213 0.6303 0.9017
Echinococcus granulosus inositol monophosphatase 1 0.0036 0.0662 0.0652
Brugia malayi beta-lactamase family protein 0.0037 0.0676 0.0954
Echinococcus multilocularis muscleblind protein 0.0164 0.4752 0.4747
Loa Loa (eye worm) PHD-finger family protein 0.0021 0.0174 0.0235
Echinococcus multilocularis inositol monophosphatase 1 0.0036 0.0662 0.0652
Loa Loa (eye worm) hypothetical protein 0.0037 0.0676 0.0954
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0324 0.4534
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.005 0.1109 0.1691
Brugia malayi Fli-1 protein 0.0221 0.6557 0.938
Loa Loa (eye worm) hypothetical protein 0.0037 0.0676 0.0954
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.1449 1
Giardia lamblia DINP protein human, muc B family 0.0038 0.0715 0.5
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.005 0.1109 0.1099
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0037 0.0676 0.0954
Loa Loa (eye worm) hypothetical protein 0.0048 0.1033 0.1465
Trypanosoma cruzi DNA polymerase kappa, putative 0.0038 0.0715 1
Schistosoma mansoni hypothetical protein 0.0047 0.1008 0.1538
Entamoeba histolytica hypothetical protein 0.0105 0.2861 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0048 0.1033 0.1576
Brugia malayi Calcitonin receptor-like protein seb-1 0.0149 0.4266 0.6098
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0715 1
Schistosoma mansoni cellular tumor antigen P53 0.0048 0.1037 0.1582
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0061 0.1449 0.144
Mycobacterium tuberculosis Conserved protein 0.0037 0.0676 0.021
Loa Loa (eye worm) hypothetical protein 0.0037 0.0676 0.0954
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0062 0.1493 0.2124
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0715 1
Trypanosoma cruzi DNA polymerase kappa, putative 0.0038 0.0715 1
Brugia malayi Ets-domain containing protein 0.0073 0.1824 0.2599
Onchocerca volvulus 0.0037 0.0676 0.0296
Loa Loa (eye worm) hypothetical protein 0.0149 0.4266 0.6098
Brugia malayi ImpB/MucB/SamB family protein 0.0038 0.0715 0.1009
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0476 0.0726
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0037 0.0676 0.0181
Echinococcus multilocularis tumor protein p63 0.0328 1 1
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0676 0.0022
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0038 0.0715 0.0269
Mycobacterium ulcerans DNA polymerase IV 0.0038 0.0715 0.067
Brugia malayi MH2 domain containing protein 0.0234 0.6989 1
Echinococcus granulosus tar DNA binding protein 0.0062 0.1493 0.1484
Loa Loa (eye worm) latrophilin receptor protein 2 0.0047 0.1008 0.143
Schistosoma mansoni smad1 5 8 and 0.0016 0.001 0.0016
Schistosoma mansoni hypothetical protein 0.0102 0.2758 0.4207
Brugia malayi Pre-SET motif family protein 0.0031 0.0476 0.0667
Mycobacterium tuberculosis Conserved protein 0.0037 0.0676 0.021
Schistosoma mansoni hypothetical protein 0.0047 0.1008 0.1538
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0061 0.145 0.1442
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0057 0.0087
Trypanosoma brucei unspecified product 0.0026 0.0338 0.4726
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0038 0.0715 0.4933
Schistosoma mansoni hypothetical protein 0.0021 0.0174 0.0266
Loa Loa (eye worm) hypothetical protein 0.0062 0.1487 0.2116
Loa Loa (eye worm) hypothetical protein 0.0037 0.0676 0.0954
Loa Loa (eye worm) hypothetical protein 0.0164 0.4752 0.6795
Mycobacterium ulcerans beta-lactamase 0.0037 0.0676 0.0181
Loa Loa (eye worm) beta-lactamase 0.0037 0.0676 0.0954
Schistosoma mansoni Smad4 0.0016 0.001 0.0016
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0038 0.0715 0.008
Mycobacterium ulcerans esterase/lipase LipP 0.0037 0.0676 0.0181
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0036 0.0662 0.5
Loa Loa (eye worm) TAR-binding protein 0.0062 0.1493 0.2124
Trypanosoma brucei DNA polymerase eta, putative 0.0038 0.0715 1
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0047 0.1008 0.0999
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0036 0.0662 0.3005
Echinococcus multilocularis dna polymerase eta 0.0038 0.0715 0.0705
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0061 0.1449 0.1404
Schistosoma mansoni smad1 5 8 and 0.0016 0.001 0.0016
Loa Loa (eye worm) MH2 domain-containing protein 0.0234 0.6989 1
Loa Loa (eye worm) hypothetical protein 0.0102 0.2758 0.3937
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0715 1
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0324 0.4534
Schistosoma mansoni inositol monophosphatase 0.0036 0.0662 0.101
Mycobacterium tuberculosis Probable esterase LipL 0.0037 0.0676 0.021
Echinococcus granulosus GA binding protein alpha chain 0.0073 0.1824 0.1816
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0235 0.7015 1
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0105 0.2861 0.2854
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.1449 1
Schistosoma mansoni smad1 5 8 and 0.0016 0.001 0.0016
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0324 0.5
Leishmania major hypothetical protein, conserved 0.0037 0.0676 0.4668
Schistosoma mansoni tar DNA-binding protein 0.0062 0.1493 0.2277
Echinococcus granulosus beta LACTamase domain containing family member 0.0037 0.0676 0.0667
Trichomonas vaginalis esterase, putative 0.0037 0.0676 0.0022
Loa Loa (eye worm) hypothetical protein 0.0044 0.0893 0.1265
Loa Loa (eye worm) RNA binding protein 0.0062 0.1493 0.2124
Brugia malayi Muscleblind-like protein 0.0164 0.4752 0.6795
Echinococcus multilocularis dna polymerase kappa 0.0038 0.0715 0.0705
Echinococcus multilocularis tar DNA binding protein 0.0062 0.1493 0.1484
Loa Loa (eye worm) fli-1 protein 0.0221 0.6557 0.938
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0037 0.0674 0.0664
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0037 0.0676 0.021
Echinococcus multilocularis muscleblind protein 1 0.0164 0.4752 0.4747
Trichomonas vaginalis penicillin-binding protein, putative 0.0037 0.0676 0.0022
Toxoplasma gondii ABC1 family protein 0.0037 0.0676 0.3131
Loa Loa (eye worm) hypothetical protein 0.0037 0.0676 0.0954
Entamoeba histolytica hypothetical protein 0.0105 0.2861 1
Mycobacterium ulcerans hypothetical protein 0.0037 0.0676 0.0181
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0038 0.0715 0.0705
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0048 0.1033 0.1576
Mycobacterium tuberculosis Conserved hypothetical protein 0.0038 0.0715 0.0269
Plasmodium vivax SET domain protein, putative 0.0031 0.0476 0.431
Echinococcus multilocularis zinc finger protein 0.002 0.014 0.0129
Schistosoma mansoni smad 0.0016 0.001 0.0016
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0047 0.1008 0.143
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0662 0.9263
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.1449 1
Schistosoma mansoni inositol monophosphatase 0.0036 0.0662 0.101
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0061 0.1449 1
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0662 0.9263
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0662 0.9263
Leishmania major DNA polymerase kappa, putative 0.0038 0.0715 0.4933
Brugia malayi beta-lactamase 0.0037 0.0676 0.0954
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0676 0.0022
Schistosoma mansoni aldehyde dehydrogenase 0.0061 0.1449 0.221
Schistosoma mansoni bromodomain containing protein 0.0065 0.1567 0.2391
Plasmodium vivax hypothetical protein, conserved 0.0037 0.0676 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.005 0.1109 0.1691
Mycobacterium tuberculosis Probable lipase LipE 0.0037 0.0676 0.021
Brugia malayi RNA recognition motif domain containing protein 0.0062 0.1493 0.2124
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0037 0.0674 0.0664
Echinococcus granulosus methyl CpG binding domain protein 2 0.0017 0.0057 0.0047
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0715 1
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0038 0.0715 0.109
Trypanosoma brucei DNA polymerase kappa, putative 0.0026 0.0338 0.4726
Schistosoma mansoni ets-related 0.0221 0.6557 1
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0676 0.9462
Trypanosoma brucei DNA polymerase kappa, putative 0.0026 0.0338 0.4726
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0047 0.1008 0.0999
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0061 0.145 0.1442
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0038 0.0715 0.1009
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0031 0.0476 0.0466
Brugia malayi Ets-domain containing protein 0.0073 0.1824 0.2599
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0047 0.1008 0.0999
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0031 0.0476 0.135
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0149 0.4266 0.6098
Trypanosoma cruzi DNA polymerase kappa, putative 0.0038 0.0715 1
Loa Loa (eye worm) hypothetical protein 0.0039 0.0754 0.1065
Trypanosoma brucei DNA polymerase IV, putative 0.0038 0.0715 1
Brugia malayi Bromodomain containing protein 0.0039 0.0751 0.1062
Brugia malayi latrophilin 2 splice variant baaae 0.0102 0.2758 0.3937
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0061 0.1449 0.144
Trypanosoma brucei DNA polymerase IV, putative 0.0038 0.0715 1
Mycobacterium tuberculosis Probable hydrolase 0.0037 0.0676 0.021
Brugia malayi Inositol-1 0.0036 0.0662 0.0934
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.005 0.1109 0.1573
Echinococcus granulosus zinc finger protein 0.002 0.014 0.0129
Brugia malayi TAR-binding protein 0.0062 0.1493 0.2124
Loa Loa (eye worm) hypothetical protein 0.0042 0.0831 0.1176
Trichomonas vaginalis DNA polymerase eta, putative 0.0038 0.0715 0.008
Loa Loa (eye worm) hypothetical protein 0.0037 0.0676 0.0954
Loa Loa (eye worm) inositol-1 0.0036 0.0662 0.0934
Loa Loa (eye worm) hypothetical protein 0.0048 0.1037 0.1471
Loa Loa (eye worm) hypothetical protein 0.0164 0.4752 0.6795
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.005 0.1109 0.1099
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0048 0.1033 0.1024
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.005 0.1109 0.1099
Brugia malayi Latrophilin receptor protein 2 0.0047 0.1008 0.143
Schistosoma mansoni tar DNA-binding protein 0.0062 0.1493 0.2277
Brugia malayi hypothetical protein 0.0026 0.0324 0.0449
Schistosoma mansoni aldehyde dehydrogenase 0.0061 0.1449 0.221
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0715 1
Entamoeba histolytica deoxycytidyl transferase, putative 0.0038 0.0715 0.024
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0037 0.0676 0.0954
Trypanosoma brucei DNA polymerase IV, putative 0.0038 0.0715 1
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0073 0.1824 0.2599
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0023 0.0237 0.0226
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0715 1
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0676 0.9462
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.005 0.1109 0.1691
Loa Loa (eye worm) hypothetical protein 0.0072 0.1811 0.2579
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0715 1
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0031 0.0476 0.0726
Trypanosoma brucei hypothetical protein, conserved 0.0037 0.0676 0.9462
Mycobacterium tuberculosis Probable lipase LipD 0.0037 0.0676 0.021
Schistosoma mansoni transcription factor LCR-F1 0.0105 0.2861 0.4364
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0715 1
Onchocerca volvulus 0.0037 0.0676 0.0296
Trypanosoma cruzi DNA polymerase eta, putative 0.0038 0.0715 1
Schistosoma mansoni hypothetical protein 0.0047 0.1008 0.1538
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0047 0.1008 0.0999
Echinococcus granulosus fetal alzheimer antigen falz 0.0023 0.0237 0.0226
Echinococcus granulosus dna polymerase kappa 0.0038 0.0715 0.0705
Trypanosoma brucei PAB1-binding protein , putative 0.0026 0.0324 0.4534
Brugia malayi Bromodomain containing protein 0.0077 0.195 0.278
Leishmania major DNA polymerase eta, putative 0.0038 0.0715 0.4933
Echinococcus multilocularis GPCR, family 2 0.0047 0.1008 0.0999
Schistosoma mansoni gabp alpha 0.0073 0.1824 0.2783
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.044 0.043
Brugia malayi hypothetical protein 0.0105 0.2861 0.4085
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.005 0.1109 0.1573
Brugia malayi Pre-SET motif family protein 0.0213 0.6303 0.9017
Trichomonas vaginalis set domain proteins, putative 0.0242 0.7243 1
Loa Loa (eye worm) bromodomain containing protein 0.0018 0.0077 0.0096
Echinococcus granulosus dna polymerase eta 0.0038 0.0715 0.0705
Trypanosoma brucei unspecified product 0.0038 0.0715 1
Trypanosoma brucei unspecified product 0.0026 0.0338 0.4726
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0037 0.0676 0.021
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0016 0.001 0.0016
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0037 0.0676 0.021
Schistosoma mansoni zinc finger protein 0.002 0.014 0.0213
Schistosoma mansoni tar DNA-binding protein 0.0062 0.1493 0.2277
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0324 0.5
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.0676 0.1032
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0715 1
Entamoeba histolytica hypothetical protein 0.0105 0.2861 1
Echinococcus granulosus histone lysine methyltransferase setb 0.0048 0.1033 0.1024
Brugia malayi ImpB/MucB/SamB family protein 0.0038 0.0715 0.1009
Schistosoma mansoni DNA polymerase eta 0.0038 0.0715 0.109
Onchocerca volvulus 0.0048 0.1037 0.0829
Trypanosoma cruzi DNA polymerase kappa, putative 0.0038 0.0715 1
Mycobacterium tuberculosis Conserved protein 0.0037 0.0676 0.021
Brugia malayi PHD-finger family protein 0.0025 0.0314 0.0435
Onchocerca volvulus 0.0037 0.0676 0.0296
Trichomonas vaginalis penicillin-binding protein, putative 0.0037 0.0676 0.0022
Trypanosoma brucei DNA polymerase kappa, putative 0.0026 0.0338 0.4726
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.0676 0.1032
Leishmania major hypothetical protein, conserved 0.0026 0.0324 0.2237
Mycobacterium leprae Probable lipase LipE 0.0037 0.0676 1
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0676 0.0022
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0057 0.0087
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0017 0.0057 0.0047
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0662 0.4569
Loa Loa (eye worm) hypothetical protein 0.0026 0.0324 0.0449
Brugia malayi hypothetical protein 0.0017 0.0032 0.0031
Loa Loa (eye worm) hypothetical protein 0.0047 0.1008 0.143
Schistosoma mansoni hypothetical protein 0.0105 0.2861 0.4364
Loa Loa (eye worm) transcription factor SMAD2 0.0234 0.6989 1
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.005 0.1109 0.1099
Mycobacterium leprae conserved hypothetical protein 0.0037 0.0676 1

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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