Detailed information for compound 108438

Basic information

Technical information
  • TDR Targets ID: 108438
  • Name: 2-[(4-fluorobenzoyl)-methylamino]acetic acid
  • MW: 211.19 | Formula: C10H10FNO3
  • H donors: 1 H acceptors: 3 LogP: 1.08 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: CN(C(=O)c1ccc(cc1)F)CC(=O)O
  • InChi: 1S/C10H10FNO3/c1-12(6-9(13)14)10(15)7-2-4-8(11)5-3-7/h2-5H,6H2,1H3,(H,13,14)
  • InChiKey: YSKWGOCVDOEFKF-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 2-[(4-fluorobenzoyl)-methyl-amino]acetic acid
  • 2-[[(4-fluorophenyl)-oxomethyl]-methylamino]acetic acid
  • 2-[(4-fluorophenyl)carbonyl-methyl-amino]ethanoic acid
  • BBV-011100

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Rattus norvegicus Aldose reductase Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Trichomonas vaginalis aldo-keto reductase, putative Get druggable targets OG5_126583 All targets in OG5_126583
Echinococcus multilocularis aldo keto reductase family 1, member B4 Get druggable targets OG5_126583 All targets in OG5_126583
Trichomonas vaginalis aldo/keto reductase, putative Get druggable targets OG5_126583 All targets in OG5_126583
Echinococcus multilocularis aldo keto reductase Get druggable targets OG5_126583 All targets in OG5_126583
Loa Loa (eye worm) oxidoreductase Get druggable targets OG5_126583 All targets in OG5_126583
Loa Loa (eye worm) oxidoreductase Get druggable targets OG5_126583 All targets in OG5_126583
Echinococcus granulosus aldo keto reductase Get druggable targets OG5_126583 All targets in OG5_126583
Toxoplasma gondii aldose reductase, putative Get druggable targets OG5_126583 All targets in OG5_126583
Onchocerca volvulus Get druggable targets OG5_126583 All targets in OG5_126583
Schistosoma japonicum IPR001395,Aldo/keto reductase,domain-containing Get druggable targets OG5_126583 All targets in OG5_126583
Echinococcus granulosus aldo keto reductase family 1 member B4 Get druggable targets OG5_126583 All targets in OG5_126583
Trypanosoma congolense aldo-keto reductase, putative Get druggable targets OG5_126583 All targets in OG5_126583
Schistosoma mansoni aldo-keto reductase Get druggable targets OG5_126583 All targets in OG5_126583
Trichomonas vaginalis aldo-keto reductase, putative Get druggable targets OG5_126583 All targets in OG5_126583
Trichomonas vaginalis dihydrodiol dehydrogenase, putative Get druggable targets OG5_126583 All targets in OG5_126583
Echinococcus multilocularis aldo keto reductase family 1, member B4 Get druggable targets OG5_126583 All targets in OG5_126583
Leishmania major aldo-keto reductase-like protein Get druggable targets OG5_126583 All targets in OG5_126583
Leishmania mexicana prostaglandin f2-alpha synthase Get druggable targets OG5_126583 All targets in OG5_126583
Trichomonas vaginalis aldo/keto reductase, putative Get druggable targets OG5_126583 All targets in OG5_126583
Trichomonas vaginalis aldo-keto reductase, putative Get druggable targets OG5_126583 All targets in OG5_126583
Trypanosoma cruzi aldo/keto reductase, putative Get druggable targets OG5_126583 All targets in OG5_126583
Entamoeba histolytica aldose reductase, putative Get druggable targets OG5_126583 All targets in OG5_126583
Echinococcus multilocularis aldo keto reductase family 1, member B4 Get druggable targets OG5_126583 All targets in OG5_126583
Trypanosoma cruzi aldo-keto reductase Get druggable targets OG5_126583 All targets in OG5_126583
Onchocerca volvulus Get druggable targets OG5_126583 All targets in OG5_126583
Leishmania infantum aldo-keto reductase-like protein Get druggable targets OG5_126583 All targets in OG5_126583
Trichomonas vaginalis aldo-keto reductase, putative Get druggable targets OG5_126583 All targets in OG5_126583
Leishmania major aldehyde reductase, putative,oxidoreductase, putative Get druggable targets OG5_126583 All targets in OG5_126583
Echinococcus multilocularis aldo keto reductase family 1, member B4 Get druggable targets OG5_126583 All targets in OG5_126583
Leishmania braziliensis aldehyde reductase, putative,oxidoreductase, putative Get druggable targets OG5_126583 All targets in OG5_126583
Trichomonas vaginalis aldo-keto reductase, putative Get druggable targets OG5_126583 All targets in OG5_126583
Leishmania braziliensis prostaglandin f synthase, putative Get druggable targets OG5_126583 All targets in OG5_126583
Echinococcus multilocularis aldo keto reductase family 1, member B4 Get druggable targets OG5_126583 All targets in OG5_126583
Mycobacterium ulcerans oxidoreductase Get druggable targets OG5_126583 All targets in OG5_126583
Echinococcus multilocularis aldo keto reductase family 1, member B4 Get druggable targets OG5_126583 All targets in OG5_126583
Candida albicans similar to mammalian aldo/keto reductases Get druggable targets OG5_126583 All targets in OG5_126583
Echinococcus granulosus hypothetical protein Get druggable targets OG5_126583 All targets in OG5_126583
Entamoeba histolytica aldose reductase, putative Get druggable targets OG5_126583 All targets in OG5_126583
Trichomonas vaginalis aldo-keto reductase, putative Get druggable targets OG5_126583 All targets in OG5_126583
Trichomonas vaginalis aldo-keto reductase, putative Get druggable targets OG5_126583 All targets in OG5_126583
Onchocerca volvulus Get druggable targets OG5_126583 All targets in OG5_126583
Trichomonas vaginalis aldo-keto reductase, putative Get druggable targets OG5_126583 All targets in OG5_126583
Trypanosoma brucei gambiense prostaglandin f synthase. putative Get druggable targets OG5_126583 All targets in OG5_126583
Echinococcus granulosus aldo keto reductase Get druggable targets OG5_126583 All targets in OG5_126583
Brugia malayi oxidoreductase, aldo/keto reductase family protein Get druggable targets OG5_126583 All targets in OG5_126583
Echinococcus granulosus aldehyde reductase Get druggable targets OG5_126583 All targets in OG5_126583
Leishmania braziliensis aldo-keto reductase-like protein Get druggable targets OG5_126583 All targets in OG5_126583
Echinococcus multilocularis aldo keto reductase Get druggable targets OG5_126583 All targets in OG5_126583
Schistosoma japonicum ko:K00011 aldehyde reductase [EC1.1.1.21], putative Get druggable targets OG5_126583 All targets in OG5_126583
Trypanosoma brucei gambiense aldo-keto reductase, putative Get druggable targets OG5_126583 All targets in OG5_126583
Leishmania braziliensis prostaglandin f2-alpha synthase/D-arabinose dehydrogenase Get druggable targets OG5_126583 All targets in OG5_126583
Schistosoma mansoni pol-related Get druggable targets OG5_126583 All targets in OG5_126583
Schistosoma mansoni aldo-keto reductase Get druggable targets OG5_126583 All targets in OG5_126583
Trichomonas vaginalis aldo-keto reductase, putative Get druggable targets OG5_126583 All targets in OG5_126583
Trypanosoma brucei prostaglandin f synthase Get druggable targets OG5_126583 All targets in OG5_126583
Mycobacterium leprae Conserved hypothetical protein Get druggable targets OG5_126583 All targets in OG5_126583
Trichomonas vaginalis aldo/keto reductase, putative Get druggable targets OG5_126583 All targets in OG5_126583
Trichomonas vaginalis dihydrodiol dehydrogenase, putative Get druggable targets OG5_126583 All targets in OG5_126583
Echinococcus granulosus aldo keto reductase Get druggable targets OG5_126583 All targets in OG5_126583
Mycobacterium leprae PROBABLE OXIDOREDUCTASE Get druggable targets OG5_126583 All targets in OG5_126583
Echinococcus granulosus aldo keto reductase family 1 member B4 Get druggable targets OG5_126583 All targets in OG5_126583
Loa Loa (eye worm) oxidoreductase Get druggable targets OG5_126583 All targets in OG5_126583
Onchocerca volvulus Get druggable targets OG5_126583 All targets in OG5_126583
Trichomonas vaginalis aldo-keto reductase, putative Get druggable targets OG5_126583 All targets in OG5_126583
Entamoeba histolytica aldose reductase, putative Get druggable targets OG5_126583 All targets in OG5_126583
Onchocerca volvulus Get druggable targets OG5_126583 All targets in OG5_126583
Leishmania major prostaglandin f2-alpha synthase/D-arabinose dehydrogenase Get druggable targets OG5_126583 All targets in OG5_126583
Trichomonas vaginalis aldo-keto reductase, putative Get druggable targets OG5_126583 All targets in OG5_126583
Leishmania infantum aldehyde reductase, putative,oxidoreductase, putative Get druggable targets OG5_126583 All targets in OG5_126583
Echinococcus granulosus aldo keto reductase family 1 member B4 Get druggable targets OG5_126583 All targets in OG5_126583
Leishmania donovani prostaglandin f synthase, putative Get druggable targets OG5_126583 All targets in OG5_126583
Trypanosoma congolense prostaglandin f synthase, putative Get druggable targets OG5_126583 All targets in OG5_126583
Neospora caninum Oxidoreductase, aldo/keto reductase family, related Get druggable targets OG5_126583 All targets in OG5_126583
Leishmania donovani aldo-keto reductase-like protein Get druggable targets OG5_126583 All targets in OG5_126583
Brugia malayi oxidoreductase, aldo/keto reductase family protein Get druggable targets OG5_126583 All targets in OG5_126583
Leishmania mexicana aldehyde reductase, putative,oxidoreductase, putative Get druggable targets OG5_126583 All targets in OG5_126583
Leishmania infantum prostaglandin f2-alpha synthase/D-arabinose dehydrogenase Get druggable targets OG5_126583 All targets in OG5_126583
Loa Loa (eye worm) oxidoreductase Get druggable targets OG5_126583 All targets in OG5_126583
Echinococcus granulosus aldo keto reductase family 1 member B4 Get druggable targets OG5_126583 All targets in OG5_126583
Onchocerca volvulus Get druggable targets OG5_126583 All targets in OG5_126583
Candida albicans Aldose reductase Get druggable targets OG5_126583 All targets in OG5_126583
Mycobacterium tuberculosis Probable oxidoreductase Get druggable targets OG5_126583 All targets in OG5_126583
Echinococcus multilocularis aldo keto reductase family 1, member B4 Get druggable targets OG5_126583 All targets in OG5_126583
Leishmania donovani prostaglandin f2-alpha synthase Get druggable targets OG5_126583 All targets in OG5_126583
Trichomonas vaginalis aldo-keto reductase, putative Get druggable targets OG5_126583 All targets in OG5_126583
Echinococcus granulosus aldo keto reductase family 1 member B4 Get druggable targets OG5_126583 All targets in OG5_126583
Candida albicans see also nonallelic CaP19.2244 Get druggable targets OG5_126583 All targets in OG5_126583
Echinococcus multilocularis aldehyde reductase Get druggable targets OG5_126583 All targets in OG5_126583
Leishmania mexicana prostaglandin f synthase, putative Get druggable targets OG5_126583 All targets in OG5_126583
Echinococcus granulosus aldo keto reductase family 1 member B4 Get druggable targets OG5_126583 All targets in OG5_126583
Candida albicans similar to mammalian aldo/keto reductases Get druggable targets OG5_126583 All targets in OG5_126583
Echinococcus multilocularis aldo keto reductase family 1, member B4 Get druggable targets OG5_126583 All targets in OG5_126583
Candida albicans see also nonallelic CaP19.2244 Get druggable targets OG5_126583 All targets in OG5_126583
Echinococcus multilocularis aldo keto reductase Get druggable targets OG5_126583 All targets in OG5_126583
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126583 All targets in OG5_126583
Trichomonas vaginalis dihydrodiol dehydrogenase, putative Get druggable targets OG5_126583 All targets in OG5_126583
Candida albicans similar to mammalian aldo/keto reductases Get druggable targets OG5_126583 All targets in OG5_126583
Brugia malayi oxidoreductase, aldo/keto reductase family protein Get druggable targets OG5_126583 All targets in OG5_126583
Giardia lamblia Aldose reductase Get druggable targets OG5_126583 All targets in OG5_126583
Leishmania donovani aldehyde reductase, putative Get druggable targets OG5_126583 All targets in OG5_126583
Echinococcus multilocularis aldo keto reductase family 1, member B4 Get druggable targets OG5_126583 All targets in OG5_126583
Candida albicans Aldose reductase Get druggable targets OG5_126583 All targets in OG5_126583
Giardia lamblia Aldose reductase Get druggable targets OG5_126583 All targets in OG5_126583
Echinococcus multilocularis aldo keto reductase family 1, member B4 Get druggable targets OG5_126583 All targets in OG5_126583
Echinococcus granulosus aldo keto reductase family 1 member B4 Get druggable targets OG5_126583 All targets in OG5_126583
Leishmania infantum prostaglandin f synthase, putative Get druggable targets OG5_126583 All targets in OG5_126583
Echinococcus granulosus aldo keto reductase family 1 member B4 Get druggable targets OG5_126583 All targets in OG5_126583
Leishmania mexicana aldo-keto reductase-like protein Get druggable targets OG5_126583 All targets in OG5_126583
Trypanosoma brucei aldo-keto reductase, putative Get druggable targets OG5_126583 All targets in OG5_126583
Echinococcus granulosus aldo keto reductase family 1 member B4 Get druggable targets OG5_126583 All targets in OG5_126583
Echinococcus multilocularis aldo keto reductase Get druggable targets OG5_126583 All targets in OG5_126583
Brugia malayi oxidoreductase, aldo/keto reductase family protein Get druggable targets OG5_126583 All targets in OG5_126583
Leishmania major prostaglandin f synthase, putative Get druggable targets OG5_126583 All targets in OG5_126583
Echinococcus multilocularis aldo keto reductase family 1, member B4 Get druggable targets OG5_126583 All targets in OG5_126583
Loa Loa (eye worm) oxidoreductase Get druggable targets OG5_126583 All targets in OG5_126583
Candida albicans similar to mammalian aldo/keto reductases Get druggable targets OG5_126583 All targets in OG5_126583
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Neospora caninum aldo/keto reductase family oxidoreductase, putative Aldose reductase   316 aa 295 aa 21.4 %
Onchocerca volvulus Aldose reductase   316 aa 321 aa 40.2 %
Trypanosoma cruzi aldo/keto reductase, putative Aldose reductase   316 aa 309 aa 26.9 %
Candida albicans putative aryl alcohol dehydrogenase Aldose reductase   316 aa 320 aa 19.4 %
Candida albicans see also nonallelic CaP19.6816 Aldose reductase   316 aa 281 aa 29.2 %
Candida albicans D-arabinose dehydrogenase, NADP-dependent Aldose reductase   316 aa 277 aa 37.2 %
Candida albicans aryl alcohol dehydrogenase Aldose reductase   316 aa 320 aa 19.4 %
Candida albicans putative aryl alcohol dehydrogenase Aldose reductase   316 aa 329 aa 19.8 %
Leishmania braziliensis aldo/keto reductase, putative,aldo/keto reductase family-like protein Aldose reductase   316 aa 267 aa 27.3 %
Candida albicans similar to putative aryl alcohol dehydrogenase family Aldose reductase   316 aa 320 aa 19.7 %
Toxoplasma gondii aldo/keto reductase family oxidoreductase Aldose reductase   316 aa 296 aa 26.7 %
Candida albicans aryl alcohol dehydrogenase Aldose reductase   316 aa 330 aa 18.8 %
Mycobacterium tuberculosis Conserved protein Aldose reductase   316 aa 335 aa 24.2 %
Onchocerca volvulus Multiple coagulation factor deficiency protein 2 homolog Aldose reductase   316 aa 320 aa 40.3 %
Mycobacterium ulcerans hypothetical protein Aldose reductase   316 aa 334 aa 24.3 %
Candida albicans see also nonallelic CaP19.6816 Aldose reductase   316 aa 281 aa 29.2 %
Candida albicans D-arabinose dehydrogenase, NADP-dependent Aldose reductase   316 aa 277 aa 37.2 %
Candida albicans aryl alcohol dehydrogenase Aldose reductase   316 aa 330 aa 18.8 %
Onchocerca volvulus Aldose reductase   316 aa 314 aa 37.3 %
Candida albicans aryl alcohol dehydrogenase Aldose reductase   316 aa 320 aa 19.4 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Chlamydia trachomatis proline--tRNA ligase 0.0022 0.0147 0.2978
Echinococcus granulosus lysyl tRNA synthetase 0.0046 0.0425 0.0734
Echinococcus multilocularis voltage gated potassium channel subunit 0.0011 0.0024 0.0027
Plasmodium vivax calcium-dependent protein kinase, putative 0.0066 0.0659 0.0637
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0092 0.0961 0.166
Echinococcus multilocularis solute carrier family 22 0.0029 0.0229 0.0261
Trichomonas vaginalis glucose transporter, putative 0.0063 0.0631 0.107
Plasmodium falciparum pyruvate kinase 0.0033 0.0274 0.0251
Trichomonas vaginalis esterase, putative 0.0034 0.0289 0.0478
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0062 0.062 0.0597
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0062 0.062 0.107
Onchocerca volvulus 0.0019 0.0119 0.1425
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0062 0.062 0.0916
Echinococcus granulosus General substrate transporter 0.0176 0.1934 0.3341
Giardia lamblia Kinase, CMGC CDK 0.0133 0.1436 0.4049
Trichomonas vaginalis conserved hypothetical protein 0.0446 0.5064 0.8746
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0017 0.009 0.0333
Brugia malayi Probable 3',5'-cyclic phosphodiesterase T04D3.3, putative 0.0062 0.062 0.23
Echinococcus multilocularis GPCR, family 2 0.0017 0.009 0.0103
Loa Loa (eye worm) hypothetical protein 0.0062 0.062 0.1079
Onchocerca volvulus 0.0029 0.0229 0.2732
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0038 0.0339 0.0586
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0062 0.062 0.0706
Schistosoma mansoni cyclin-dependent kinase 5 activator 0.0504 0.5742 0.992
Onchocerca volvulus 0.0029 0.0229 0.2732
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0508 0.5788 1
Leishmania major aldehyde reductase, putative,oxidoreductase, putative 0.0038 0.0339 0.0564
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0229 0.0373
Echinococcus multilocularis glycyl tRNA synthetase 0.0012 0.0029 0.0033
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0066 0.0659 0.0637
Echinococcus granulosus FAD linked sulfhydryl oxidase ALR 0.0032 0.0271 0.0468
Brugia malayi hypothetical protein 0.0029 0.0229 0.0849
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.0029 0.0229 0.1225
Schistosoma mansoni cpg binding protein 0.0027 0.021 0.0362
Loa Loa (eye worm) hypothetical protein 0.0017 0.009 0.0156
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.0508 0.5788 1
Onchocerca volvulus 0.0017 0.009 0.1072
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0311 0.3504 0.6044
Brugia malayi Pyruvate kinase, muscle isozyme 0.0033 0.0274 0.1019
Echinococcus granulosus dual specificity 0.0182 0.2006 0.3465
Trichomonas vaginalis aldo-keto reductase, putative 0.0038 0.0339 0.0564
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0062 0.062 0.107
Trichomonas vaginalis aldo-keto reductase, putative 0.0038 0.0339 0.0564
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0205 0.2267 0.3917
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0062 0.062 0.0916
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0229 0.0373
Onchocerca volvulus 0.0029 0.0229 0.2732
Onchocerca volvulus 0.0029 0.0229 0.2732
Echinococcus multilocularis lipoxygenase domain containing protein 0.0019 0.0119 0.0136
Onchocerca volvulus 0.0029 0.0229 0.2732
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0017 0.009 0.0102
Toxoplasma gondii facilitative glucose transporter GT1 0.0205 0.2267 0.3405
Mycobacterium tuberculosis Probable lipase LipD 0.0034 0.0289 0.1151
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0508 0.5788 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0311 0.3504 0.6044
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0062 0.062 0.0916
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0062 0.062 0.23
Plasmodium vivax hexose transporter 0.0205 0.2267 0.2249
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0034 0.0289 0.0504
Leishmania major aldo/keto reductase, putative,aldo/keto reductase family-like protein 0.0011 0.0024 0.0018
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0508 0.5788 1
Schistosoma mansoni hypothetical protein 0.0017 0.009 0.0155
Echinococcus multilocularis Threonyl tRNA synthetase, C 0.0012 0.0029 0.0033
Trichomonas vaginalis aldo-keto reductase, putative 0.0011 0.0024 0.0018
Leishmania major protein kinase, putative 0.0066 0.0658 0.1117
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0038 0.0339 0.0386
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0062 0.062 0.105
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0133 0.1436 0.2149
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0062 0.062 0.0916
Loa Loa (eye worm) hypothetical protein 0.0017 0.009 0.0156
Mycobacterium leprae Possible oxidoreductase 0.0011 0.0024 0.006
Trypanosoma cruzi hypothetical protein, conserved 0.0034 0.0289 0.0478
Trichomonas vaginalis aldo-keto reductase, putative 0.0038 0.0339 0.0564
Trichomonas vaginalis aldo-keto reductase, putative 0.0011 0.0024 0.0018
Loa Loa (eye worm) hypothetical protein 0.0029 0.0229 0.0398
Echinococcus granulosus GPCR family 2 0.0017 0.009 0.0155
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0152 0.1658 0.9349
Leishmania major hypothetical protein, conserved 0.0029 0.0229 0.0373
Echinococcus multilocularis pyruvate kinase 0.0033 0.0274 0.0313
Loa Loa (eye worm) hypothetical protein 0.0029 0.0229 0.0398
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0038 0.0339 0.0386
Entamoeba histolytica protein kinase, putative 0.0182 0.2006 0.5725
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0229 0.0373
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0311 0.3504 0.6044
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0062 0.062 0.0916
Echinococcus granulosus pyruvate kinase 0.0017 0.009 0.0155
Brugia malayi casein kinase I 0.0081 0.0837 0.3108
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0017 0.009 0.0333
Trichomonas vaginalis aldo-keto reductase, putative 0.0011 0.0024 0.0018
Echinococcus granulosus lipoxygenase domain containing protein 0.0019 0.0119 0.0206
Toxoplasma gondii hypothetical protein 0.0446 0.5064 0.7629
Entamoeba histolytica aldose reductase, putative 0.0038 0.0339 0.0967
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0346 0.3911 0.6749
Trichomonas vaginalis conserved hypothetical protein 0.0446 0.5064 0.8746
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0229 0.0373
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0508 0.5788 1
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0765 0.8774 1
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0062 0.062 0.105
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0229 0.0373
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0066 0.0658 0.075
Loa Loa (eye worm) hypothetical protein 0.0017 0.009 0.0156
Plasmodium falciparum calcium-dependent protein kinase 2 0.0066 0.0659 0.0637
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0508 0.5788 1
Echinococcus granulosus casein kinase i 0.0081 0.0837 0.1447
Toxoplasma gondii sugar transporter ST3 0.0029 0.0229 0.0326
Trypanosoma brucei aldo-keto reductase, putative 0.0038 0.0339 0.0564
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0017 0.009 0.0155
Trypanosoma cruzi casein kinase, putative 0.0081 0.0837 0.1427
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0038 0.0339 0.0586
Loa Loa (eye worm) hypothetical protein 0.0224 0.2497 0.4349
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0229 0.0373
Echinococcus granulosus glycine receptor subunit alpha 1 0.0017 0.009 0.0155
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0066 0.0658 0.1137
Schistosoma mansoni nAChR subunit 0.0017 0.009 0.0155
Echinococcus multilocularis cyclin dependent kinase 1 0.0133 0.1436 0.1637
Brugia malayi hypothetical protein 0.0241 0.2694 1
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0034 0.0289 0.1074
Entamoeba histolytica hypothetical protein 0.0046 0.0425 0.1212
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0038 0.0339 0.0386
Toxoplasma gondii lysine-tRNA ligase 0.0046 0.0425 0.0622
Trypanosoma brucei cdc2-related kinase 3 0.0133 0.1436 0.2463
Brugia malayi CXXC zinc finger family protein 0.0027 0.021 0.0778
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0038 0.0339 0.0386
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0046 0.0425 0.2339
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0038 0.0339 0.1258
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0034 0.0289 0.1151
Schistosoma mansoni glucose transporter 0.0029 0.0229 0.0395
Schistosoma mansoni pyruvate kinase 0.0017 0.009 0.0155
Treponema pallidum fructose-bisphosphate aldolase 0.0311 0.3504 1
Schistosoma mansoni protein kinase 0.0066 0.0658 0.1137
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0081 0.0837 0.1458
Leishmania major prostaglandin f2-alpha synthase/D-arabinose dehydrogenase 0.0038 0.0339 0.0564
Plasmodium vivax hypothetical protein, conserved 0.0162 0.1773 0.1753
Onchocerca volvulus 0.0019 0.0119 0.1425
Echinococcus granulosus aldo keto reductase 0.0038 0.0339 0.0586
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0092 0.0961 0.166
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0017 0.009 0.0155
Giardia lamblia Aldose reductase 0.0038 0.0339 0.0893
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0182 0.2006 0.3451
Echinococcus granulosus RUN 0.0019 0.0119 0.0206
Trypanosoma cruzi hexose transporter, putative 0.0063 0.0631 0.107
Echinococcus granulosus lipoxygenase domain containing protein 0.0019 0.0119 0.0206
Onchocerca volvulus 0.0029 0.0229 0.2732
Trypanosoma cruzi aldo-keto reductase 0.0038 0.0339 0.0564
Toxoplasma gondii histone lysine methyltransferase SET1 0.0051 0.0491 0.0722
Brugia malayi lysyl-tRNA synthetase 0.0046 0.0425 0.1576
Trypanosoma brucei ERV/ALR sulfhydryl oxidase domain-containing protein 0.0032 0.0271 0.0446
Echinococcus granulosus high affinity cAMP specific 3'5' cyclic 0.0062 0.062 0.107
Onchocerca volvulus 0.0017 0.009 0.1072
Echinococcus multilocularis RUN 0.0019 0.0119 0.0136
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.0274 0.3277
Giardia lamblia hypothetical protein 0.0062 0.062 0.1701
Plasmodium falciparum proline--tRNA ligase 0.0072 0.0725 0.0703
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0229 0.0373
Brugia malayi Pyruvate kinase, alpha/beta domain containing protein 0.001 0.001 0.0037
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0066 0.0658 0.2444
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0229 0.0373
Entamoeba histolytica glycyl-tRNA synthetase, putative 0.0012 0.0029 0.0082
Loa Loa (eye worm) major facilitator superfamily transporter 0.0029 0.0229 0.0398
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0017 0.009 0.0155
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0229 0.0373
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0062 0.062 0.0597
Trichomonas vaginalis pyruvate kinase, putative 0.0033 0.0274 0.0452
Trichomonas vaginalis threonyl-tRNA synthetase, putative 0.0012 0.0029 0.0027
Mycobacterium ulcerans hypothetical protein 0.0034 0.0289 0.157
Toxoplasma gondii casein kinase I 0.0081 0.0837 0.1245
Echinococcus multilocularis casein kinase I alpha 0.0081 0.0837 0.0954
Echinococcus granulosus beta LACTamase domain containing family member 0.0034 0.0289 0.05
Toxoplasma gondii pyruvate kinase PyK1 0.0033 0.0274 0.0395
Trypanosoma brucei prostaglandin f synthase 0.0038 0.0339 0.0564
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0017 0.009 0.0156
Trichomonas vaginalis sugar transporter, putative 0.0063 0.0631 0.107
Trichomonas vaginalis conserved hypothetical protein 0.0205 0.2267 0.3903
Schistosoma mansoni serine/threonine protein kinase 0.0133 0.1436 0.2481
Leishmania major cAMP phosphodiesterase A, putative;with=GeneDB:LinJ18_V3.1100 0.0062 0.062 0.105
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0311 0.3504 1
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0066 0.0659 0.0975
Entamoeba histolytica cell division protein kinase 2, putative 0.0133 0.1436 0.4098
Plasmodium falciparum calcium-dependent protein kinase 1 0.0066 0.0659 0.0637
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0508 0.5788 1
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0017 0.009 0.0102
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0224 0.2497 0.4301
Trichomonas vaginalis aldo/keto reductase, putative 0.0038 0.0339 0.0564
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0017 0.009 0.0102
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0133 0.1436 0.2481
Echinococcus multilocularis beta LACTamase domain containing family member 0.0034 0.0289 0.033
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0229 0.0373
Giardia lamblia Prolyl-tRNA synthetase 0.0061 0.0607 0.1664
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0017 0.009 0.0155
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0062 0.062 0.105
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0229 0.0373
Schistosoma mansoni pol-related 0.0038 0.0339 0.0586
Echinococcus granulosus casein kinase I alpha 0.0081 0.0837 0.1447
Trichomonas vaginalis aldo-keto reductase, putative 0.0038 0.0339 0.0564
Echinococcus multilocularis General substrate transporter 0.0176 0.1934 0.2204
Echinococcus granulosus aldehyde reductase 0.0027 0.021 0.0363
Giardia lamblia Fructose-bisphosphate aldolase 0.0311 0.3504 1
Entamoeba histolytica casein kinase 1, putative 0.0081 0.0837 0.239
Loa Loa (eye worm) hypothetical protein 0.0504 0.5742 1
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0066 0.0658 0.1137
Leishmania major hypothetical protein, conserved 0.0062 0.062 0.105
Schistosoma mansoni protein kinase 0.0066 0.0658 0.1137
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0017 0.009 0.0102
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0508 0.5788 1
Toxoplasma gondii aldo/keto reductase family oxidoreductase 0.0011 0.0024 0.0016
Mycobacterium ulcerans pyruvate kinase 0.0033 0.0274 0.1485
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0017 0.009 0.0333
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0038 0.0339 0.1258
Mycobacterium ulcerans putative regulatory protein 0.0162 0.1773 1
Trichomonas vaginalis aldo-keto reductase, putative 0.0038 0.0339 0.0564
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0062 0.062 0.105
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0062 0.062 0.0916
Mycobacterium leprae conserved hypothetical protein 0.0162 0.1773 1
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0229 0.0373
Giardia lamblia Hexose transporter 0.0029 0.0229 0.0576
Loa Loa (eye worm) ACC-1 protein 0.0017 0.009 0.0156
Loa Loa (eye worm) hypothetical protein 0.0029 0.0229 0.0398
Trypanosoma cruzi hexose transporter, putative 0.0063 0.0631 0.107
Loa Loa (eye worm) hypothetical protein 0.0038 0.0339 0.059
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0092 0.0961 0.1095
Echinococcus granulosus aldo keto reductase 0.0038 0.0339 0.0586
Schistosoma mansoni transcription factor LCR-F1 0.0034 0.0289 0.0499
Echinococcus granulosus Sugar transporter ERD6 protein 0.0029 0.0229 0.0395
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0017 0.009 0.0102
Loa Loa (eye worm) latrophilin receptor protein 2 0.0017 0.009 0.0157
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0346 0.3911 0.6749
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0229 0.0373
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0066 0.0658 0.075
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0017 0.009 0.0155
Loa Loa (eye worm) hypothetical protein 0.0012 0.0029 0.005
Brugia malayi Sugar transporter family protein 0.0029 0.0229 0.0849
Trichomonas vaginalis CAMK family protein kinase 0.0066 0.0658 0.1117
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0092 0.0961 0.166
Plasmodium falciparum mitogen-activated protein kinase 2 0.0334 0.3765 0.375
Onchocerca volvulus 0.0038 0.0339 0.4048
Mycobacterium leprae Conserved hypothetical protein 0.0027 0.021 0.1121
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0038 0.0339 0.1258
Leishmania major glucose transporter, lmgt1 0.0063 0.0631 0.107
Mycobacterium ulcerans sugar transporter 0.0029 0.0229 0.1225
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0017 0.009 0.0155
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0508 0.5788 1
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0062 0.062 0.107
Onchocerca volvulus 0.0029 0.0229 0.2732
Loa Loa (eye worm) threonyl-tRNA synthetase 0.0012 0.0029 0.005
Brugia malayi excitatory GABA receptor EXP-1A 0.0017 0.009 0.0333
Echinococcus granulosus Polycystic kidney disease protein 0.0019 0.0119 0.0206
Schistosoma mansoni hypothetical protein 0.0386 0.4374 0.7556
Onchocerca volvulus 0.0017 0.009 0.1072
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0038 0.0339 0.0386
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0224 0.2497 0.9268
Plasmodium vivax proline--tRNA ligase, putative 0.0072 0.0725 0.0703
Loa Loa (eye worm) hypothetical protein 0.0066 0.0658 0.1147
Trypanosoma cruzi cdc2-related kinase 1 0.0133 0.1436 0.2463
Giardia lamblia Kinase, CMGC CDK 0.0133 0.1436 0.4049
Trypanosoma brucei cAMP phosphodiesterase A, putative 0.0062 0.062 0.105
Plasmodium vivax hypothetical protein, conserved 0.0034 0.0289 0.0266
Echinococcus multilocularis pyruvate kinase 0.0033 0.0274 0.0313
Loa Loa (eye worm) hypothetical protein 0.0062 0.062 0.1079
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0508 0.5788 1
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0217 0.2414 1
Loa Loa (eye worm) hypothetical protein 0.0017 0.009 0.0156
Schistosoma mansoni nAChR subunit 0.0017 0.009 0.0155
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0508 0.5788 1
Trypanosoma brucei glucose transporter, putative 0.0063 0.0631 0.107
Trichomonas vaginalis CMGC family protein kinase 0.0133 0.1436 0.2463
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0062 0.062 0.0597
Trichomonas vaginalis aldo-keto reductase, putative 0.0038 0.0339 0.0564
Onchocerca volvulus 0.0029 0.0229 0.2732
Echinococcus multilocularis aldo keto reductase 0.0038 0.0339 0.0386
Echinococcus granulosus Threonyl tRNA synthetase C 0.0012 0.0029 0.0049
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0032 0.0271 0.0446
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0074 0.0755 0.1285
Leishmania major hypothetical protein, conserved 0.0032 0.0271 0.0446
Trichomonas vaginalis conserved hypothetical protein 0.0162 0.1773 0.3047
Schistosoma mansoni nAChR subunit 0.0017 0.009 0.0155
Loa Loa (eye worm) hypothetical protein 0.0023 0.016 0.0278
Trypanosoma brucei cAMP-specific phosphodiesterase, putative 0.0062 0.062 0.105
Toxoplasma gondii oxidoreductase, aldo/keto reductase family protein 0.0011 0.0024 0.0016
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0062 0.062 0.0916
Schistosoma mansoni nAChR subunit 0.0017 0.009 0.0155
Loa Loa (eye worm) oxidoreductase 0.0038 0.0339 0.059
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0508 0.5788 1
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0229 0.0373
Mycobacterium tuberculosis Two component sensor histidine kinase DosT 0.0162 0.1773 0.7329
Loa Loa (eye worm) hypothetical protein 0.0017 0.009 0.0156
Trypanosoma brucei THT1 - hexose transporter, putative 0.0063 0.0631 0.107
Trypanosoma cruzi aldo/keto reductase, putative 0.0038 0.0339 0.0564
Schistosoma mansoni polycystin 1-related 0.0019 0.0119 0.0206
Echinococcus multilocularis casein kinase I alpha 0.0081 0.0837 0.0954
Echinococcus multilocularis aldehyde reductase 0.0027 0.021 0.024
Loa Loa (eye worm) hypothetical protein 0.0036 0.0316 0.055
Loa Loa (eye worm) hypothetical protein 0.0019 0.0119 0.0208
Loa Loa (eye worm) hypothetical protein 0.0061 0.0607 0.1057
Leishmania major pyruvate kinase 0.0033 0.0274 0.0452
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0229 0.0373
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0205 0.2267 0.3917
Leishmania major glucose transporter, lmgt2 0.0063 0.0631 0.107
Schistosoma mansoni hypothetical protein 0.0034 0.0289 0.0499
Treponema pallidum prolyl-tRNA synthetase 0.0022 0.0147 0.0339
Entamoeba histolytica cell division protein kinase 2, putative 0.0133 0.1436 0.4098
Onchocerca volvulus 0.0029 0.0229 0.2732
Trichomonas vaginalis aldo-keto reductase, putative 0.0038 0.0339 0.0564
Echinococcus multilocularis lysyl tRNA synthetase 0.0046 0.0425 0.0484
Echinococcus granulosus glycine receptor subunit alpha 1 0.0017 0.009 0.0155
Mycobacterium tuberculosis Two component sensor histidine kinase DevS 0.0162 0.1773 0.7329
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0034 0.0289 0.1151
Echinococcus granulosus solute carrier family 22 0.0029 0.0229 0.0395
Loa Loa (eye worm) hypothetical protein 0.0029 0.0229 0.0398
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0508 0.5788 1
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0229 0.0373
Loa Loa (eye worm) hypothetical protein 0.0017 0.009 0.0156
Plasmodium vivax protein kinase Crk2 0.0133 0.1436 0.1416
Echinococcus granulosus glycyl tRNA synthetase 0.0012 0.0029 0.0049
Schistosoma mansoni hypothetical protein 0.0019 0.0119 0.0206
Onchocerca volvulus 0.0074 0.0755 0.9019
Plasmodium falciparum phosphodiesterase gamma, putative 0.0062 0.062 0.0597
Leishmania major threonyl-tRNA synthetase, putative 0.0012 0.0029 0.0027
Loa Loa (eye worm) CXXC zinc finger family protein 0.0027 0.021 0.0365
Schistosoma mansoni cpg binding protein 0.0029 0.0228 0.0393
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.0029 0.0229 0.1225
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0311 0.3504 0.6044
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.0508 0.5788 0.6597
Trypanosoma brucei glucose transporter, putative 0.0063 0.0631 0.107
Loa Loa (eye worm) hypothetical protein 0.0017 0.009 0.0156
Loa Loa (eye worm) hypothetical protein 0.0017 0.009 0.0156
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0017 0.009 0.0102
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0508 0.5788 1
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0034 0.0289 0.033
Echinococcus granulosus hypothetical protein 0.0038 0.0339 0.0586
Trypanosoma cruzi cdc2-related kinase 1 0.0133 0.1436 0.2463
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0062 0.062 0.23
Loa Loa (eye worm) hypothetical protein 0.0034 0.0289 0.0504
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0092 0.0961 0.1673
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.0508 0.5788 1
Entamoeba histolytica hypothetical protein 0.0034 0.0289 0.0825
Brugia malayi latrophilin 2 splice variant baaae 0.0036 0.0316 0.1173
Trichomonas vaginalis aldo/keto reductase, putative 0.0038 0.0339 0.0564
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0029 0.0229 0.0395
Echinococcus multilocularis casein kinase I alpha 0.0081 0.0837 0.0954
Brugia malayi Cation transporter family protein 0.0017 0.009 0.0333
Mycobacterium leprae Probable lysyl-tRNA synthase LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0039 0.0345 0.1885
Plasmodium falciparum calcium-dependent protein kinase 4 0.0066 0.0659 0.0637
Loa Loa (eye worm) hypothetical protein 0.0029 0.0229 0.0398
Plasmodium falciparum protein kinase 7 0.0581 0.6634 0.6626
Mycobacterium tuberculosis Probable conserved integral membrane transport protein 0.0029 0.0229 0.0898
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0017 0.009 0.0333
Plasmodium vivax multidomain scavenger receptor, putative 0.0019 0.0119 0.0096
Loa Loa (eye worm) hypothetical protein 0.0029 0.0229 0.0398
Toxoplasma gondii Erv1 / Alr family protein 0.0032 0.0271 0.0389
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0229 0.0373
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0038 0.0339 0.0586
Brugia malayi hypothetical protein 0.0034 0.0289 0.1073
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0017 0.009 0.0333
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0062 0.062 0.105
Loa Loa (eye worm) hypothetical protein 0.0017 0.009 0.0156
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0229 0.0373
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0229 0.0373
Onchocerca volvulus 0.0029 0.0229 0.2732
Trypanosoma cruzi hypothetical protein, conserved 0.0062 0.062 0.105
Echinococcus multilocularis cyclin dependent kinase 5 0.0133 0.1436 0.1637
Trichomonas vaginalis conserved hypothetical protein 0.0063 0.0631 0.107
Echinococcus granulosus solute carrier family 22 0.0029 0.0229 0.0395
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0017 0.009 0.0156
Onchocerca volvulus 0.0029 0.0229 0.2732
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0038 0.0339 0.0386
Entamoeba histolytica hypothetical protein 0.0034 0.0289 0.0825
Echinococcus multilocularis FAD linked sulfhydryl oxidase ALR 0.0032 0.0271 0.0309
Loa Loa (eye worm) pyruvate kinase 0.0033 0.0274 0.0478
Loa Loa (eye worm) hypothetical protein 0.0029 0.0229 0.0398
Toxoplasma gondii Erv1 / Alr family protein 0.0032 0.0271 0.0389
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0038 0.0339 0.0586
Loa Loa (eye worm) hypothetical protein 0.0053 0.0511 0.0889
Trypanosoma cruzi sugar transporter, putative 0.0029 0.0229 0.0373
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0017 0.009 0.0102
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0034 0.0289 0.1151
Brugia malayi Sugar transporter family protein 0.0205 0.2267 0.8415
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0182 0.2006 0.3451
Echinococcus granulosus casein kinase I delta 0.0081 0.0837 0.1447
Schistosoma mansoni glucose transport protein 0.0205 0.2267 0.3917
Schistosoma mansoni sugar transporter 0.0029 0.0229 0.0395
Trichomonas vaginalis sugar transporter, putative 0.0063 0.0631 0.107
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0017 0.009 0.0103
Trypanosoma brucei pyruvate kinase 1, putative 0.0033 0.0274 0.0452
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0508 0.5788 1
Loa Loa (eye worm) hypothetical protein 0.0017 0.009 0.0156
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0066 0.0658 0.1117
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.0224 0.2497 0.9268
Onchocerca volvulus 0.0038 0.0339 0.4048
Toxoplasma gondii sugar transporter ST2 0.0029 0.0229 0.0326
Echinococcus multilocularis geminin 0.016 0.1751 0.1995
Trypanosoma cruzi threonyl-tRNA synthetase, putative 0.0012 0.0029 0.0027
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0508 0.5788 1
Onchocerca volvulus 0.0017 0.009 0.1072
Trichomonas vaginalis D-aminoacylase, putative 0.0034 0.0289 0.0478
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0229 0.0373
Trypanosoma brucei glucose transporter, putative 0.0063 0.0631 0.107
Echinococcus granulosus tumor protein p63 0.0331 0.3737 0.6455
Mycobacterium leprae Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase) (ThrRS) (Threonine-tRNA ligase) 0.0012 0.0029 0.0088
Echinococcus granulosus dnaJ subfamily B 0.0386 0.4374 0.7556
Schistosoma mansoni rab6-interacting 0.0019 0.0119 0.0206
Loa Loa (eye worm) hypothetical protein 0.0029 0.0229 0.0398
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0062 0.062 0.107
Mycobacterium ulcerans prolyl-tRNA synthetase 0.0022 0.0147 0.0758
Trypanosoma cruzi hypothetical protein, conserved 0.0062 0.062 0.105
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0062 0.062 0.0597
Onchocerca volvulus 0.0038 0.0339 0.4048
Echinococcus multilocularis glycine receptor subunit beta 0.0017 0.009 0.0102
Trypanosoma brucei threonyl-tRNA synthetase, putative 0.0012 0.0029 0.0027
Loa Loa (eye worm) glutamate-cysteine ligase modifier subunit 0.0011 0.0024 0.0041
Onchocerca volvulus Putative transporter 0.0029 0.0229 0.2732
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0062 0.062 0.23
Leishmania major casein kinase, putative 0.0081 0.0837 0.1427
Entamoeba histolytica protein kinase, putative 0.0182 0.2006 0.5725
Brugia malayi Major Facilitator Superfamily protein 0.0029 0.0229 0.0849
Brugia malayi Protein kinase domain containing protein 0.0182 0.2006 0.7445
Trypanosoma cruzi glucose transporter, putative 0.0029 0.0229 0.0373
Loa Loa (eye worm) sugar transporter 0.0205 0.2267 0.3949
Giardia lamblia CAMP-specific 3,5-cyclic phosphodiesterase 4B 0.0062 0.062 0.1701
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0061 0.0607 0.3374
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0034 0.0289 0.157
Plasmodium vivax casein kinase 1, putative 0.0081 0.0837 0.0816
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0046 0.0425 0.0713
Loa Loa (eye worm) major facilitator superfamily transporter 0.0029 0.0229 0.0398
Schistosoma mansoni aldo-keto reductase 0.0038 0.0339 0.0586
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.004 0.0359 0.06
Loa Loa (eye worm) hypothetical protein 0.0046 0.0425 0.074
Toxoplasma gondii hypothetical protein 0.0162 0.1773 0.2658
Giardia lamblia Pyruvate kinase 0.0017 0.009 0.0176
Trypanosoma cruzi casein kinase, putative 0.0081 0.0837 0.1427
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0508 0.5788 1
Echinococcus granulosus casein kinase I delta 0.0081 0.0837 0.1447
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0066 0.0659 0.0975
Trypanosoma cruzi hexose transporter, putative 0.0029 0.0229 0.0373
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0017 0.009 0.0155
Leishmania major prostaglandin f synthase, putative 0.0038 0.0339 0.0564
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0334 0.3765 0.375
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0061 0.0607 0.1048
Loa Loa (eye worm) hypothetical protein 0.0029 0.0229 0.0398
Plasmodium falciparum threonine--tRNA ligase 0.0012 0.0029 0.0005
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0038 0.0339 0.0386
Loa Loa (eye worm) hypothetical protein 0.0029 0.0229 0.0398
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0017 0.009 0.0155
Trypanosoma cruzi hexose transporter 0.0063 0.0631 0.107
Echinococcus granulosus casein kinase I alpha 0.0081 0.0837 0.1447
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0229 0.0373
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0029 0.0229 0.0261
Trichomonas vaginalis conserved hypothetical protein 0.0508 0.5788 1
Echinococcus multilocularis solute carrier family 22 0.0029 0.0229 0.0261
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0062 0.062 0.0916
Echinococcus granulosus aldo keto reductase family 1, member B4 0.0011 0.0024 0.0041
Onchocerca volvulus 0.0034 0.0289 0.3456
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0017 0.009 0.0155
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0038 0.0339 0.0564
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0229 0.0373
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0229 0.0373
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0182 0.2006 0.3451
Loa Loa (eye worm) glycyl-tRNA synthetase 0.0012 0.0029 0.005
Echinococcus multilocularis aldo keto reductase 0.0038 0.0339 0.0386
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0061 0.0607 0.1732
Loa Loa (eye worm) hypothetical protein 0.0029 0.0229 0.0398
Loa Loa (eye worm) hypothetical protein 0.0017 0.009 0.0156
Mycobacterium tuberculosis Conserved protein 0.0034 0.0289 0.1151
Schistosoma mansoni nAChR subunit 0.0017 0.009 0.0155
Schistosoma mansoni serine/threonine protein kinase 0.0081 0.0837 0.1447
Trichomonas vaginalis CMGC family protein kinase 0.0133 0.1436 0.2463
Trypanosoma cruzi pyruvate kinase 2, putative 0.0033 0.0274 0.0452
Entamoeba histolytica alcohol dehydrogenase, putative 0.0011 0.0024 0.0068
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0017 0.009 0.0156
Trypanosoma cruzi hypothetical protein, conserved 0.0062 0.062 0.105
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0062 0.062 0.107
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0054 0.0523 0.0596
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0017 0.009 0.0333
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0229 0.0373
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0072 0.0725 0.1232
Schistosoma mansoni sugar transporter 0.0029 0.0229 0.0395
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0508 0.5788 1
Schistosoma mansoni hypothetical protein 0.0036 0.0316 0.0546
Schistosoma mansoni hypothetical protein 0.0017 0.009 0.0155
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0062 0.062 0.0916
Onchocerca volvulus 0.0038 0.0339 0.4048
Plasmodium falciparum calcium-dependent protein kinase 5 0.0066 0.0659 0.0637
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0062 0.062 0.0916
Schistosoma mansoni lipoxygenase 0.0054 0.0523 0.0903
Mycobacterium tuberculosis Probable hydrolase 0.0034 0.0289 0.1151
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0334 0.3765 0.5667
Echinococcus granulosus pyruvate kinase 0.0033 0.0274 0.0474
Schistosoma mansoni loxhd1 0.0019 0.0119 0.0206
Brugia malayi hypothetical protein 0.0019 0.0119 0.0443
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.0224 0.2497 0.4314
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0205 0.2267 0.3917
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0062 0.062 0.107
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0062 0.062 0.0597
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0017 0.009 0.0156
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0133 0.1436 0.2463
Echinococcus multilocularis lipoxygenase domain containing protein 0.0019 0.0119 0.0136
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0017 0.009 0.0333
Leishmania major hypothetical protein, conserved 0.0034 0.0289 0.0478
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0229 0.0373
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0062 0.062 0.0706
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0229 0.0373
Loa Loa (eye worm) hypothetical protein 0.0162 0.1773 0.3087
Mycobacterium leprae Probable lipase LipE 0.0034 0.0289 0.157
Schistosoma mansoni serine/threonine protein kinase 0.0182 0.2006 0.3465
Loa Loa (eye worm) hypothetical protein 0.0062 0.062 0.1079
Schistosoma mansoni calcium/calmodulin-dependent 35-cyclic nucleotide phosphodiesterase 0.0062 0.062 0.107
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0032 0.0271 0.0446
Trichomonas vaginalis conserved hypothetical protein 0.0062 0.062 0.105
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0508 0.5788 1
Leishmania major glucose transporter/membrane transporter D2, putative 0.0063 0.0631 0.107
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0508 0.5788 1
Brugia malayi hypothetical protein 0.0029 0.0229 0.0849
Toxoplasma gondii glycyl-tRNA synthetase 0.0012 0.0029 0.0023
Schistosoma mansoni glucose transport protein 0.0205 0.2267 0.3917
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0017 0.009 0.0333
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0034 0.0289 0.0499
Loa Loa (eye worm) hypothetical protein 0.0017 0.009 0.0156
Brugia malayi NADH-dependent xylose reductase 0.0011 0.0024 0.0088
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0066 0.0658 0.1147
Brugia malayi Cation transporter family protein 0.0017 0.009 0.0333
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0092 0.0961 0.166
Echinococcus granulosus glycine receptor subunit beta 0.0017 0.009 0.0155
Schistosoma mansoni cellular tumor antigen P53 0.0048 0.0457 0.079
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0017 0.009 0.0155
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.0274 0.3277
Loa Loa (eye worm) hypothetical protein 0.0017 0.009 0.0156
Trypanosoma brucei glucose transporter, putative 0.0063 0.0631 0.107
Trypanosoma cruzi hexose transporter, putative 0.0035 0.0297 0.0492
Onchocerca volvulus 0.0017 0.009 0.1072
Schistosoma mansoni hypothetical protein 0.0205 0.2267 0.3917
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.0224 0.2497 0.4314
Echinococcus granulosus glycine receptor subunit alpha 1 0.0017 0.009 0.0155
Mycobacterium ulcerans esterase/lipase LipP 0.0034 0.0289 0.157
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0017 0.009 0.0156
Entamoeba histolytica hypothetical protein 0.0182 0.2006 0.5725
Loa Loa (eye worm) hypothetical protein 0.0029 0.0229 0.0398
Plasmodium vivax FAD-linked sulfhydryl oxidase ERV1, putative 0.0032 0.0271 0.0248
Plasmodium falciparum FAD-linked sulfhydryl oxidase ERV1, putative 0.0032 0.0271 0.0248
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0054 0.0523 0.0903
Plasmodium vivax cyclic nucleotide phosphodiesterase, putative 0.0062 0.062 0.0597
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0205 0.2267 0.2584
Onchocerca volvulus 0.0048 0.0457 0.5463
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0034 0.0289 0.05
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0062 0.062 0.0916
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0062 0.062 0.105
Trichomonas vaginalis CK1 family protein kinase 0.0081 0.0837 0.1427
Trypanosoma brucei glucose transporter, putative 0.0063 0.0631 0.107
Schistosoma mansoni hypothetical protein 0.0017 0.009 0.0155
Loa Loa (eye worm) pyruvate kinase-PB 0.0023 0.016 0.0278
Mycobacterium ulcerans threonyl-tRNA synthetase 0.0012 0.0029 0.0088
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0092 0.0961 0.1095
Loa Loa (eye worm) LGC-31 protein 0.0017 0.009 0.0156
Loa Loa (eye worm) oxidoreductase 0.0038 0.0339 0.059
Onchocerca volvulus 0.0038 0.0339 0.4048
Trichomonas vaginalis CK1 family protein kinase 0.0081 0.0837 0.1427
Plasmodium falciparum calcium-dependent protein kinase 3 0.0066 0.0659 0.0637
Onchocerca volvulus 0.0029 0.0229 0.2732
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0038 0.0339 0.0586
Trypanosoma brucei glucose transporter 1E 0.0063 0.0631 0.107
Plasmodium vivax sugar transporter, putative 0.0029 0.0229 0.0205
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0072 0.0725 0.1232
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0508 0.5788 1
Trypanosoma cruzi hypothetical protein, conserved 0.0062 0.062 0.105
Giardia lamblia Aldose reductase 0.0038 0.0339 0.0893
Entamoeba histolytica hypothetical protein 0.0034 0.0289 0.0825
Brugia malayi Cam kinase protein 1 0.0066 0.0658 0.2444
Echinococcus granulosus calcium dependent protein kinase 0.0059 0.0577 0.0996
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0508 0.5788 1
Echinococcus granulosus solute carrier family 22 0.0029 0.0229 0.0395
Trypanosoma cruzi hypothetical protein, conserved 0.0062 0.062 0.105
Entamoeba histolytica hypothetical protein 0.0034 0.0289 0.0825
Mycobacterium ulcerans glycyl-tRNA synthetase 0.0012 0.0029 0.0088
Schistosoma mansoni sugar transporter 0.0029 0.0229 0.0395
Plasmodium falciparum LCCL domain-containing protein 0.0019 0.0119 0.0096
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0017 0.009 0.0155
Loa Loa (eye worm) hypothetical protein 0.0017 0.009 0.0156
Echinococcus multilocularis casein kinase I delta 0.0081 0.0837 0.0954
Trypanosoma brucei hypothetical protein, conserved 0.0062 0.062 0.105
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0017 0.009 0.0333
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0046 0.0425 0.2339
Trichomonas vaginalis aldo-keto reductase, putative 0.0038 0.0339 0.0564
Trypanosoma cruzi hypothetical protein, conserved 0.0062 0.062 0.105
Mycobacterium ulcerans oxidoreductase 0.0038 0.0339 0.1852
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0062 0.062 0.105
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0508 0.5788 1
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0508 0.5788 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0311 0.3504 0.6044
Echinococcus granulosus high affinity cgmp specific 3' 5' cyclic 0.0062 0.062 0.107
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.0508 0.5788 1
Brugia malayi Calcitonin receptor-like protein seb-1 0.0053 0.0511 0.1896
Onchocerca volvulus 0.0034 0.0289 0.3456
Brugia malayi Protein kinase domain containing protein 0.0133 0.1436 0.5329
Schistosoma mansoni nAChR subunit 0.0017 0.009 0.0155
Loa Loa (eye worm) hypothetical protein 0.0029 0.0229 0.0398
Trypanosoma brucei glucose transporter, putative 0.0063 0.0631 0.107
Loa Loa (eye worm) hypothetical protein 0.0175 0.1924 0.335
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0066 0.0658 0.1137
Brugia malayi Pyruvate kinase, M2 isozyme 0.0033 0.0274 0.1019
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0508 0.5788 1
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0311 0.3504 1
Echinococcus multilocularis solute carrier family 22 0.0029 0.0229 0.0261
Loa Loa (eye worm) hypothetical protein 0.0017 0.009 0.0156
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0062 0.062 0.0916
Trypanosoma cruzi hypothetical protein, conserved 0.0034 0.0289 0.0478
Trichomonas vaginalis penicillin-binding protein, putative 0.0034 0.0289 0.0478
Echinococcus granulosus voltage gated potassium channel subunit 0.0011 0.0024 0.0041
Mycobacterium tuberculosis Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase)(ThrRS) (threonine-tRNA ligase) 0.0012 0.0029 0.0065
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0205 0.2267 0.2584
Trichomonas vaginalis D-aminoacylase, putative 0.0034 0.0289 0.0478
Echinococcus granulosus nAChR subunit 0.0017 0.009 0.0155
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0311 0.3504 0.6044
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0062 0.062 0.0916
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0017 0.009 0.0102
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0058 0.0562 0.0971
Entamoeba histolytica protein kinase, putative 0.0066 0.0658 0.1879
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0061 0.0607 0.1048
Echinococcus granulosus cyclin dependent kinase 1 0.0133 0.1436 0.2481
Mycobacterium ulcerans hypothetical protein 0.0011 0.0024 0.006
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0508 0.5788 1
Loa Loa (eye worm) hypothetical protein 0.0017 0.009 0.0156
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0061 0.0607 0.2252
Brugia malayi probable proline-trna synthetase - fission yeast, putative 0.0012 0.0029 0.0106
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0053 0.0511 0.1896
Entamoeba histolytica threonyl-tRNA synthetase, putative 0.0012 0.0029 0.0082
Brugia malayi Latrophilin receptor protein 2 0.0017 0.009 0.0334
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0205 0.2267 0.2584
Giardia lamblia Pyruvate kinase 0.0033 0.0274 0.0707
Mycobacterium tuberculosis Probable esterase LipL 0.0034 0.0289 0.1151
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0062 0.062 0.0597
Entamoeba histolytica protein kinase domain containing protein 0.0182 0.2006 0.5725
Brugia malayi cell division control protein 2 homolog 0.0133 0.1436 0.5329
Schistosoma mansoni aldo-keto reductase 0.0038 0.0339 0.0586
Echinococcus granulosus cpg binding protein 0.0029 0.0228 0.0393
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0017 0.009 0.0155
Schistosoma mansoni hypothetical protein 0.016 0.1751 0.3024
Echinococcus multilocularis dual specificity 0.0182 0.2006 0.2286
Toxoplasma gondii sugar transporter ST1 0.0029 0.0229 0.0326
Brugia malayi hypothetical protein 0.0019 0.0119 0.0443
Leishmania major hypothetical protein, conserved 0.0062 0.062 0.105
Schistosoma mansoni lysyl-tRNA synthetase 0.0046 0.0425 0.0734
Loa Loa (eye worm) hypothetical protein 0.0034 0.0289 0.0504
Entamoeba histolytica alcohol dehydrogenase, putative 0.0011 0.0024 0.0068
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0061 0.0607 0.2252
Chlamydia trachomatis lysine--tRNA ligase 0.0046 0.0425 1
Plasmodium falciparum GAF domain-related protein, putative 0.0162 0.1773 0.1753
Echinococcus granulosus geminin 0.016 0.1751 0.3024
Plasmodium vivax pyruvate kinase 2, putative 0.0017 0.009 0.0066
Schistosoma mansoni pyruvate kinase 0.0033 0.0274 0.0474
Mycobacterium leprae PROBABLE OXIDOREDUCTASE 0.0038 0.0339 0.1852
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0061 0.0607 0.0692
Loa Loa (eye worm) hypothetical protein 0.0033 0.0274 0.0478
Loa Loa (eye worm) hypothetical protein 0.0029 0.0229 0.0398
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0034 0.0289 0.05
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0046 0.0425 0.2339
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0038 0.0339 0.0586
Giardia lamblia Lysyl-tRNA synthetase 0.0046 0.0425 0.114
Trypanosoma cruzi threonyl-tRNA synthetase, putative 0.0012 0.0029 0.0027
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0017 0.009 0.0102
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0062 0.062 0.105
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0017 0.009 0.0155
Loa Loa (eye worm) hypothetical protein 0.005 0.0473 0.0824
Echinococcus granulosus cyclin dependent kinase 5 activator 1 0.0504 0.5742 0.992
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0017 0.009 0.0156
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0205 0.2267 0.2584
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0229 0.0373
Toxoplasma gondii aldose reductase, putative 0.0038 0.0339 0.0492
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0066 0.0659 0.0637
Loa Loa (eye worm) beta-lactamase 0.0034 0.0289 0.0504
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0229 0.0373
Loa Loa (eye worm) hypothetical protein 0.0034 0.0289 0.0504
Brugia malayi beta-lactamase family protein 0.0034 0.0289 0.1074
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0229 0.0373
Giardia lamblia Hypothetical protein 0.0062 0.062 0.1701
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0182 0.2006 0.3493
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0229 0.0373
Loa Loa (eye worm) hypothetical protein 0.0017 0.009 0.0156
Echinococcus multilocularis pyruvate kinase 0.0026 0.0195 0.0222
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0133 0.1436 0.2501
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0072 0.0725 0.1075
Trichomonas vaginalis CMGC family protein kinase 0.0133 0.1436 0.2463
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0017 0.009 0.0102
Entamoeba histolytica casein kinase, putative 0.0081 0.0837 0.239
Leishmania major lysyl-tRNA synthetase, putative 0.0046 0.0425 0.0713
Onchocerca volvulus 0.0038 0.0339 0.4048
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0017 0.009 0.0333
Onchocerca volvulus 0.0027 0.021 0.2504
Trypanosoma brucei casein kinase I, isoform 2 0.0081 0.0837 0.1427
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0311 0.3504 0.6044
Giardia lamblia Kinase, CK1 Casein kinase 0.0081 0.0837 0.2327
Loa Loa (eye worm) hypothetical protein 0.0175 0.1924 0.335
Toxoplasma gondii ABC1 family protein 0.0034 0.0289 0.0417
Mycobacterium tuberculosis Conserved protein 0.0034 0.0289 0.1151
Trichomonas vaginalis aldo-keto reductase, putative 0.0038 0.0339 0.0564
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0061 0.0607 0.1048
Trypanosoma cruzi hexose transporter, putative 0.0063 0.0631 0.107
Loa Loa (eye worm) oxidoreductase 0.0038 0.0339 0.059
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.0029 0.0229 1
Toxoplasma gondii pyruvate kinase PyKII 0.0017 0.009 0.0116
Brugia malayi beta-lactamase family protein 0.0034 0.0289 0.1074
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0038 0.0339 0.0586
Trypanosoma brucei aldo/keto reductase, putative 0.0011 0.0024 0.0018
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0072 0.0725 0.1232
Trypanosoma brucei THT1 - hexose transporter, putative 0.0063 0.0631 0.107
Echinococcus granulosus pyruvate kinase 0.0017 0.009 0.0155
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0062 0.062 0.0916
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0062 0.062 0.107
Loa Loa (eye worm) hypothetical protein 0.0029 0.0229 0.0398
Trichomonas vaginalis conserved hypothetical protein 0.0063 0.0631 0.107
Echinococcus multilocularis aldo keto reductase 0.0038 0.0339 0.0386
Toxoplasma gondii GAF domain-containing protein 0.0162 0.1773 0.2658
Schistosoma mansoni protein kinase 0.0066 0.0658 0.1137
Entamoeba histolytica protein kinase, putative 0.0066 0.0658 0.1879
Trypanosoma cruzi pyruvate kinase 2, putative 0.0033 0.0274 0.0452
Brugia malayi Major Facilitator Superfamily protein 0.0029 0.0229 0.0849
Mycobacterium leprae Probable pyruvate kinase PykA 0.0033 0.0274 0.1485
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0229 0.0373
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0038 0.0339 0.0386
Trichomonas vaginalis sugar transporter, putative 0.0063 0.0631 0.107
Trichomonas vaginalis calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0062 0.062 0.105
Trypanosoma cruzi casein kinase, putative 0.0081 0.0837 0.1427
Loa Loa (eye worm) hypothetical protein 0.0048 0.0457 0.0797
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0038 0.0339 0.0386
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0017 0.009 0.0333
Mycobacterium tuberculosis Probable lipase LipE 0.0034 0.0289 0.1151
Schistosoma mansoni nAChR subunit 0.0017 0.009 0.0155
Echinococcus multilocularis cyclin dependent kinase 5 activator 1 0.0504 0.5742 0.6545
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0229 0.0373
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0346 0.3911 0.6749
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0182 0.2006 0.3451
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0062 0.062 0.107
Schistosoma mansoni protein kinase 0.0081 0.0837 0.1447
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0081 0.0837 0.1458
Schistosoma mansoni hypothetical protein 0.016 0.1751 0.3024
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0133 0.1436 0.2501
Echinococcus granulosus solute carrier family 22 0.0029 0.0229 0.0395
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0038 0.0339 0.0564
Trichomonas vaginalis D-aminoacylase, putative 0.0034 0.0289 0.0478
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0066 0.0658 0.1147
Echinococcus granulosus glycine receptor subunit beta 0.0017 0.009 0.0155
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0152 0.1658 0.9349
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.0274 0.3277
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0038 0.0339 0.1258
Plasmodium falciparum protein kinase 5 0.0133 0.1436 0.1416
Loa Loa (eye worm) hypothetical protein 0.0241 0.2694 0.4692
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0062 0.062 0.105
Trypanosoma brucei sugar transporter, putative 0.0029 0.0229 0.0373
Toxoplasma gondii protein kinase, putative 0.0581 0.6634 1
Mycobacterium ulcerans beta-lactamase 0.0034 0.0289 0.157
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0017 0.009 0.0333
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0081 0.0837 0.1427
Echinococcus multilocularis glycine receptor subunit beta 0.0017 0.009 0.0102
Echinococcus multilocularis dnaJ subfamily B 0.0386 0.4374 0.4985
Leishmania major pyruvate kinase 0.0033 0.0274 0.0452
Mycobacterium tuberculosis Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter) 0.0029 0.0229 0.0898
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0229 0.0373
Trypanosoma brucei hypothetical protein, conserved 0.0034 0.0289 0.0478
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0062 0.062 0.105
Loa Loa (eye worm) PDE1B protein 0.0062 0.062 0.1079
Echinococcus multilocularis synaptic vesicle 2 protein 0.0029 0.0229 0.0261
Trypanosoma brucei THT1 - hexose transporter, putative 0.0063 0.0631 0.107
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0038 0.0339 0.0386
Trypanosoma brucei glucose transporter, putative 0.0063 0.0631 0.107
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0038 0.0339 0.0564
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0229 0.0373
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0224 0.2497 0.4301
Mycobacterium ulcerans integral membrane transport protein 0.0029 0.0229 0.1225
Loa Loa (eye worm) hypothetical protein 0.0017 0.009 0.0156
Mycobacterium ulcerans putative regulatory protein 0.0162 0.1773 1
Plasmodium vivax lysine--tRNA ligase, putative 0.0046 0.0425 0.0402
Leishmania major aldo-keto reductase-like protein 0.0038 0.0339 0.0564
Loa Loa (eye worm) sugar transporter 0.0029 0.0229 0.0398
Echinococcus multilocularis tumor protein p63 0.0331 0.3737 0.4259
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0508 0.5788 1
Onchocerca volvulus 0.0011 0.0024 0.0283
Toxoplasma gondii aldo-keto reductase 0.0011 0.0024 0.0016
Loa Loa (eye worm) hypothetical protein 0.0034 0.0289 0.0504
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0017 0.009 0.0103
Trichomonas vaginalis myo-inositol transporter, putative 0.0029 0.0229 0.0373
Schistosoma mansoni lysyl-tRNA synthetase 0.0046 0.0425 0.0734
Trypanosoma cruzi cdc2-related kinase 3 0.0133 0.1436 0.2463
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0062 0.062 0.0916
Plasmodium falciparum pyruvate kinase 2 0.0017 0.009 0.0066
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0133 0.1436 0.2463
Mycobacterium leprae conserved hypothetical protein 0.0034 0.0289 0.157
Plasmodium vivax glycine--tRNA ligase, putative 0.0012 0.0029 0.0005
Trypanosoma cruzi ERV/ALR sulfhydryl oxidase domain-containing protein 0.0032 0.0271 0.0446
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0062 0.062 0.0916
Brugia malayi Cation transporter family protein 0.0017 0.009 0.0333
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0508 0.5788 1
Trichomonas vaginalis glucose transporter, putative 0.0063 0.0631 0.107
Echinococcus multilocularis pyruvate kinase 0.0017 0.009 0.0102
Toxoplasma gondii hypothetical protein 0.0162 0.1773 0.2658
Loa Loa (eye worm) hypothetical protein 0.0061 0.0607 0.1057
Echinococcus multilocularis casein kinase I delta 0.0081 0.0837 0.0954
Schistosoma mansoni camp-specific cyclic nucleotide phosphodiesterase 0.0062 0.062 0.107
Echinococcus granulosus casein kinase I alpha 0.0081 0.0837 0.1447
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0062 0.062 0.105
Loa Loa (eye worm) hypothetical protein 0.0034 0.0289 0.0504
Echinococcus multilocularis high affinity cAMP specific 3',5' cyclic 0.0062 0.062 0.0706
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0038 0.0339 0.0586
Plasmodium vivax phosphodiesterase gamma, putative 0.0062 0.062 0.0597
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0053 0.0511 0.0889
Trichomonas vaginalis penicillin-binding protein, putative 0.0034 0.0289 0.0478
Trichomonas vaginalis conserved hypothetical protein 0.0062 0.062 0.105
Plasmodium falciparum hexose transporter 0.0205 0.2267 0.2249
Echinococcus multilocularis pyruvate kinase 0.0017 0.009 0.0102
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0508 0.5788 1
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0062 0.062 0.107
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0229 0.0373
Trichomonas vaginalis CK1 family protein kinase 0.0081 0.0837 0.1427
Echinococcus multilocularis cyclin dependent kinase 1 0.0133 0.1436 0.1637
Plasmodium vivax pyruvate kinase, putative 0.0033 0.0274 0.0251
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0229 0.0373
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0017 0.009 0.0333
Onchocerca volvulus 0.0017 0.009 0.1072
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0508 0.5788 1
Brugia malayi hypothetical protein 0.0029 0.0229 0.0849
Entamoeba histolytica aldose reductase, putative 0.0038 0.0339 0.0967
Onchocerca volvulus 0.0034 0.0289 0.3456
Echinococcus granulosus aldo keto reductase 0.0038 0.0339 0.0586
Mycobacterium tuberculosis Conserved protein 0.0011 0.0024 0.0044
Schistosoma mansoni serine/threonine protein kinase 0.0133 0.1436 0.2481
Trichomonas vaginalis aldo-keto reductase, putative 0.0038 0.0339 0.0564
Trichomonas vaginalis alcohol dehydrogenase, putative 0.0011 0.0024 0.0018
Brugia malayi glycyl-tRNA synthetase 0.0012 0.0029 0.0106
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0224 0.2497 0.4301
Echinococcus multilocularis high affinity cgmp specific 3' 5' cyclic 0.0062 0.062 0.0706
Leishmania major myo-inositol/proton symporter (MIT) 0.0029 0.0229 0.0373
Entamoeba histolytica pyruvate kinase, putative 0.0023 0.016 0.0456
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0062 0.062 0.0706
Onchocerca volvulus 0.0029 0.0229 0.2732
Loa Loa (eye worm) oxidoreductase 0.0038 0.0339 0.059
Mycobacterium tuberculosis Conserved protein 0.0034 0.0289 0.1151
Mycobacterium ulcerans lipase LipD 0.0034 0.0289 0.157
Trypanosoma cruzi aldo/keto reductase, putative 0.0011 0.0024 0.0018
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0229 0.0373
Brugia malayi threonyl-tRNA synthetase, cytoplasmic 0.0012 0.0029 0.0106
Brugia malayi major facilitator superfamily protein 0.0029 0.0229 0.0849
Plasmodium falciparum phosphodiesterase delta, putative 0.0062 0.062 0.0597
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.0029 0.0229 0.0373
Schistosoma mansoni rab6-interacting 0.0019 0.0119 0.0206
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0033 0.0274 0.1088
Echinococcus multilocularis cpg binding protein 0.0029 0.0228 0.0259
Trypanosoma cruzi cyclic nucleotide phosphodiesterase 0.0062 0.062 0.105
Loa Loa (eye worm) oxidoreductase 0.0038 0.0339 0.059
Loa Loa (eye worm) hypothetical protein 0.0241 0.2694 0.4692
Loa Loa (eye worm) hypothetical protein 0.0019 0.0119 0.0208
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0029 0.0229 0.0205
Echinococcus granulosus synaptic vesicle 2 protein 0.0029 0.0229 0.0395
Brugia malayi Doublecortin family protein 0.0019 0.0119 0.0443
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0205 0.2267 0.3917
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0081 0.0837 0.1458
Schistosoma mansoni glycyl-tRNA synthetase 0.0012 0.0029 0.0049
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0229 0.0373
Giardia lamblia Sugar-proton symporter 0.0029 0.0229 0.0576
Schistosoma mansoni lipoxygenase 0.0019 0.0119 0.0206
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0062 0.062 0.105
Loa Loa (eye worm) hypothetical protein 0.0034 0.0289 0.0504
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0092 0.0961 0.166
Schistosoma mansoni pyruvate kinase 0.0033 0.0274 0.0474
Schistosoma mansoni glucose transport protein 0.0205 0.2267 0.3917
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0062 0.062 0.107
Onchocerca volvulus 0.0029 0.0229 0.2732
Echinococcus multilocularis solute carrier family 22 0.0029 0.0229 0.0261
Plasmodium falciparum casein kinase 1 0.0081 0.0837 0.0816
Trypanosoma brucei glucose transporter 2A 0.0063 0.0631 0.107
Onchocerca volvulus 0.0029 0.0229 0.2732
Trypanosoma cruzi cdc2-related kinase 3 0.0133 0.1436 0.2463
Schistosoma mansoni potassium channel beta 0.0011 0.0024 0.0041
Loa Loa (eye worm) hepatopoietin HPO2 0.0032 0.0271 0.0472
Trypanosoma cruzi casein kinase, putative 0.0081 0.0837 0.1427
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0046 0.0425 0.0713
Chlamydia trachomatis pyruvate kinase 0.0033 0.0274 0.6206
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0039 0.0345 0.1382
Echinococcus granulosus pyruvate kinase 0.0017 0.009 0.0155
Plasmodium falciparum lysine--tRNA ligase 0.0046 0.0425 0.0402
Loa Loa (eye worm) doublecortin family protein 0.0019 0.0119 0.0208
Echinococcus multilocularis casein kinase i 0.0081 0.0837 0.0954
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0017 0.009 0.0155
Trypanosoma cruzi casein kinase, putative 0.0081 0.0837 0.1427
Echinococcus multilocularis cyclin dependent kinase 0.0133 0.1436 0.1637
Trypanosoma brucei pyruvate kinase 1 0.0033 0.0274 0.0452
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0062 0.062 0.0916
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0017 0.009 0.0333
Echinococcus multilocularis pyruvate kinase 0.0017 0.009 0.0102
Loa Loa (eye worm) hypothetical protein 0.0017 0.009 0.0157
Trichomonas vaginalis conserved hypothetical protein 0.0446 0.5064 0.8746
Echinococcus granulosus cyclin dependent kinase 0.0133 0.1436 0.2481
Onchocerca volvulus 0.0029 0.0229 0.2732
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0017 0.009 0.0155
Trichomonas vaginalis sugar transport protein, putative 0.0029 0.0229 0.0373
Entamoeba histolytica aldose reductase, putative 0.0038 0.0339 0.0967
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0152 0.1658 0.6852
Echinococcus multilocularis calcium dependent protein kinase 0.0059 0.0577 0.0657
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0066 0.0658 0.075
Toxoplasma gondii transporter, major facilitator family protein 0.0029 0.0229 0.0326
Leishmania major cAMP-specific phosphodiesterase, putative 0.0062 0.062 0.105
Brugia malayi Major Facilitator Superfamily protein 0.0029 0.0229 0.0849
Schistosoma mansoni hypothetical protein 0.0017 0.009 0.0155
Echinococcus granulosus cyclin dependent kinase 5 0.0133 0.1436 0.2481
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0072 0.0725 0.1232
Trichomonas vaginalis aldo-keto reductase, putative 0.0038 0.0339 0.0564
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0311 0.3504 0.6044
Trypanosoma brucei glycyl-tRNA synthetase, putative 0.0012 0.0029 0.0027
Loa Loa (eye worm) pyruvate kinase 0.0033 0.0274 0.0478
Echinococcus multilocularis aldo keto reductase 0.0038 0.0339 0.0386
Plasmodium vivax CDK-related protein kinase 6, putative 0.0871 1 1
Loa Loa (eye worm) hypothetical protein 0.0126 0.1354 0.2357
Loa Loa (eye worm) bifunctional aminoacyl-tRNA synthetase 0.0025 0.0187 0.0326
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0061 0.0607 0.1028
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0508 0.5788 1
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0066 0.0658 0.075
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0046 0.0425 0.0713
Leishmania major glucose transporter, lmgt3 0.0063 0.0631 0.107
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0508 0.5788 1
Trichomonas vaginalis pyruvate kinase, putative 0.0033 0.0274 0.0452
Onchocerca volvulus 0.0081 0.0837 1
Schistosoma mansoni serine/threonine protein kinase 0.0066 0.0658 0.1137
Mycobacterium tuberculosis Probable oxidoreductase 0.0038 0.0339 0.1357
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0066 0.0659 0.0975
Brugia malayi Augmenter of liver regeneration 0.0032 0.0271 0.1005
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0066 0.0659 0.0637
Trypanosoma cruzi cAMP-specific phosphodiesterase, putative 0.0062 0.062 0.105
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0017 0.009 0.0155
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0024 0.0018
Loa Loa (eye worm) calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase 0.0062 0.062 0.1079
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0017 0.009 0.0333
Loa Loa (eye worm) ACC-1 protein 0.0017 0.009 0.0156
Trichomonas vaginalis aldo-keto reductase, putative 0.0038 0.0339 0.0564
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0017 0.009 0.0334
Mycobacterium ulcerans two component sensor histidine kinase DevS 0.0162 0.1773 1
Echinococcus multilocularis Polycystic kidney disease protein 0.0019 0.0119 0.0136
Loa Loa (eye worm) pyruvate kinase 0.0033 0.0274 0.0478
Echinococcus multilocularis nAChR subunit 0.0017 0.009 0.0102
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.0039 0.0345 0.1382
Onchocerca volvulus Putative nachr subunit 0.0017 0.009 0.1072
Trypanosoma brucei cdc2-related kinase 1 0.0133 0.1436 0.2463
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0062 0.062 0.107
Loa Loa (eye worm) hypothetical protein 0.0017 0.009 0.0156
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0062 0.062 0.0916
Brugia malayi casein kinase 1, delta 0.0081 0.0837 0.3108
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0072 0.0725 0.1232
Brugia malayi major facilitator superfamily protein 0.0029 0.0229 0.0849
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0133 0.1436 0.2501
Trichomonas vaginalis aldo/keto reductase, putative 0.0038 0.0339 0.0564
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0038 0.0339 0.0386
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0017 0.009 0.0333
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0229 0.0373
Toxoplasma gondii threonyl-tRNA synthetase family protein 0.0012 0.0029 0.0023
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0062 0.062 0.0706
Trypanosoma brucei glucose transporter, putative 0.0063 0.0631 0.107
Trichomonas vaginalis glucose transporter, putative 0.0029 0.0229 0.0373
Plasmodium vivax threonine--tRNA ligase, putative 0.0012 0.0029 0.0005
Brugia malayi glutamate-cysteine ligase modifier subunit 0.0011 0.0024 0.0088
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.0224 0.2497 0.2846
Schistosoma mansoni sugar transporter 0.0029 0.0229 0.0395
Brugia malayi Sugar transporter family protein 0.0029 0.0229 0.0849
Schistosoma mansoni cpg binding protein 0.0029 0.0228 0.0393
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0066 0.0658 0.1137
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0038 0.0339 0.0586
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0229 0.0373
Brugia malayi beta-lactamase 0.0034 0.0289 0.1074
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0062 0.062 0.105
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0508 0.5788 1
Echinococcus granulosus pyruvate kinase 0.0033 0.0274 0.0474
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0092 0.0961 0.3566

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 8.8 uM Inhibitory activity against aldose reductase in rat lens ChEMBL. 1906108
IC50 (binding) = 8.8 uM Inhibitory activity against aldose reductase in rat lens ChEMBL. 1906108

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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