Detailed information for compound 1095462

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 562.574 | Formula: C21H38N8O10
  • H donors: 11 H acceptors: 10 LogP: -6.31 Rotable bonds: 22
    Rule of 5 violations (Lipinski): 3
  • SMILES: OC[C@@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N)CO)C(C)C)CC(=O)N)[C@H](O)C)N
  • InChi: 1S/C21H38N8O10/c1-8(2)15(20(38)25-5-14(34)26-12(7-31)17(24)35)28-19(37)11(4-13(23)33)27-21(39)16(9(3)32)29-18(36)10(22)6-30/h8-12,15-16,30-32H,4-7,22H2,1-3H3,(H2,23,33)(H2,24,35)(H,25,38)(H,26,34)(H,27,39)(H,28,37)(H,29,36)/t9-,10+,11+,12+,15+,16+/m1/s1
  • InChiKey: NYWUVQAKHSHZRE-QUXDQXNHSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus lysine specific demethylase 5A 0.0044 0.0402 0.0382
Loa Loa (eye worm) PHD-finger family protein 0.0021 0.0105 0.0213
Brugia malayi Bromodomain containing protein 0.0036 0.0297 0.0712
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0344 0.0644
Echinococcus granulosus methyl CpG binding domain protein 2 0.0017 0.0059 0.0037
Loa Loa (eye worm) hypothetical protein 0.0039 0.0344 0.0836
Trichomonas vaginalis glutaminase, putative 0.0312 0.3863 1
Echinococcus multilocularis peregrin 0.0036 0.0297 0.0276
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0344 0.0644
Mycobacterium ulcerans esterase/lipase LipP 0.0039 0.0344 0.035
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0051 0.05 0.1928
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0039 0.0344 0.0309
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.05 0.1057
Brugia malayi jmjC domain containing protein 0.0044 0.0402 0.0987
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0046 0.0432 0.1064
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0042 0.0382 0.7457
Loa Loa (eye worm) hypothetical protein 0.0039 0.0344 0.0836
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.014 0.164 0.1938
Brugia malayi exodeoxyribonuclease III family protein 0.0021 0.0102 0.0205
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0039 0.0344 0.035
Echinococcus granulosus mitogen activated protein kinase 3 0.0051 0.05 0.0479
Brugia malayi beta-lactamase family protein 0.0039 0.0344 0.0836
Echinococcus multilocularis lysine specific demethylase 5A 0.004 0.0356 0.0335
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0286 0.3529 0.9111
Plasmodium vivax hypothetical protein, conserved 0.0033 0.0266 0.7725
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0286 0.3529 0.9111
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0059 0.0023
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0021 0.0102 0.0081
Schistosoma mansoni hypothetical protein 0.0193 0.233 0.2302
Brugia malayi PHD-finger family protein 0.0027 0.0182 0.0414
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0035 0.0284 0.0884
Echinococcus granulosus ubiquitin specific protease 41 0.0042 0.0382 0.0361
Brugia malayi glutaminase DH11.1 0.0312 0.3863 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0042 0.0382 0.0744
Brugia malayi beta-lactamase 0.0039 0.0344 0.0836
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0021 0.0102 0.3835
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0046 0.0432 0.0411
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0286 0.3529 0.9111
Echinococcus multilocularis dnaJ subfamily B 0.0412 0.5155 0.5145
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0052 0.0506 0.0486
Echinococcus granulosus peregrin 0.0036 0.0297 0.0276
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0021 0.0102 0.2963
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0042 0.0382 0.0816
Onchocerca volvulus 0.0035 0.0284 0.0237
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0035 0.0284 0.0263
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.021 0.0487
Loa Loa (eye worm) glutaminase 2 0.0312 0.3863 1
Echinococcus granulosus histone lysine methyltransferase setb 0.0052 0.0506 0.0486
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0039 0.0344 0.035
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0062 0.0635 0.0614
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.018 0.2164 0.2975
Mycobacterium tuberculosis Conserved protein 0.0039 0.0344 0.035
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0021 0.0102 0.1424
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0286 0.3529 0.9111
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0051 0.05 1
Loa Loa (eye worm) hypothetical protein 0.0033 0.0266 0.0632
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.014 0.164 0.222
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0051 0.05 0.2179
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0042 0.0382 0.1625
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0042 0.0382 0.0744
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.018 0.2164 1
Treponema pallidum fructose-bisphosphate aldolase 0.0286 0.3529 1
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0286 0.3529 1
Loa Loa (eye worm) jmjC domain-containing protein 0.0069 0.0723 0.1821
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0046 0.0432 0.0411
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0021 0.0102 0.1424
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0165 0.4787
Schistosoma mansoni cpg binding protein 0.0032 0.0257 0.0221
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.018 0.2164 0.2147
Brugia malayi Pre-SET motif family protein 0.0035 0.0284 0.068
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0051 0.05 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0286 0.3529 0.9111
Schistosoma mansoni ap endonuclease 0.0021 0.0102 0.0066
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0021 0.0102 0.0081
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0042 0.0382 0.0361
Loa Loa (eye worm) hypothetical protein 0.0071 0.0757 0.191
Loa Loa (eye worm) hypothetical protein 0.0039 0.0344 0.0836
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0042 0.0382 0.0347
Schistosoma mansoni bromodomain containing protein 0.0065 0.0681 0.0647
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0021 0.0102 0.031
Mycobacterium tuberculosis Probable hydrolase 0.0039 0.0344 0.035
Echinococcus multilocularis PHD finger protein rhinoceros 0.0033 0.0266 0.0245
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0165 0.6196
Trichomonas vaginalis penicillin-binding protein, putative 0.0039 0.0344 0.0644
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0042 0.0382 0.7457
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0052 0.0506 0.0472
Echinococcus multilocularis ubiquitin specific protease 41 0.0042 0.0382 0.0361
Loa Loa (eye worm) hypothetical protein 0.0039 0.0344 0.0836
Mycobacterium tuberculosis Probable esterase LipL 0.0039 0.0344 0.035
Brugia malayi beta-lactamase family protein 0.0039 0.0344 0.0836
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0021 0.0102 0.1424
Loa Loa (eye worm) hypothetical protein 0.0042 0.0382 0.0933
Trichomonas vaginalis penicillin-binding protein, putative 0.0039 0.0344 0.0644
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0062 0.0635 0.0614
Trypanosoma brucei hypothetical protein, conserved 0.0039 0.0344 0.665
Echinococcus granulosus zinc finger protein 0.0021 0.0113 0.0091
Brugia malayi F/Y-rich N-terminus family protein 0.0023 0.0132 0.0284
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0382 0.0744
Mycobacterium tuberculosis UDP-galactopyranose mutase Glf (UDP-GALP mutase) (NAD+-flavin adenine dinucleotide-requiring enzyme) 0.0557 0.7032 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0432 0.0397
Mycobacterium ulcerans aldehyde dehydrogenase 0.018 0.2164 0.2975
Brugia malayi jmjC domain containing protein 0.0109 0.1242 0.3173
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0042 0.0382 0.0361
Echinococcus granulosus dnaJ subfamily B 0.0412 0.5155 0.5145
Schistosoma mansoni hypothetical protein 0.0033 0.0266 0.0231
Schistosoma mansoni jumonji/arid domain-containing protein 0.0044 0.0402 0.0368
Onchocerca volvulus Alhambra homolog 0.0033 0.0266 0.0178
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0051 0.05 0.124
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0286 0.3529 0.9111
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0035 0.0284 0.0249
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0046 0.0432 0.1064
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0344 0.665
Loa Loa (eye worm) hypothetical protein 0.0039 0.0344 0.0836
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0063 0.0645 0.0611
Echinococcus multilocularis microtubule associated protein 2 0.0787 1 1
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0024 0.0151 0.0116
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0039 0.0344 0.0836
Brugia malayi Bromodomain containing protein 0.0039 0.0335 0.0812
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0042 0.0382 0.0933
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.018 0.2164 0.2147
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0039 0.0344 0.0836
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0432 0.0397
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0039 0.0344 0.0309
Giardia lamblia PHD finger protein 15 0.0033 0.0266 0.0478
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0042 0.0382 0.0816
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.014 0.164 0.222
Schistosoma mansoni hypothetical protein 0.0021 0.0105 0.007
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0286 0.3529 1
Loa Loa (eye worm) glutaminase 0.0312 0.3863 1
Toxoplasma gondii ABC1 family protein 0.0039 0.0344 0.1175
Mycobacterium ulcerans UDP-galactopyranose mutase Glf 0.0557 0.7032 1
Onchocerca volvulus 0.0039 0.0344 0.0429
Schistosoma mansoni jumonji domain containing protein 0.0086 0.0953 0.092
Loa Loa (eye worm) hypothetical protein 0.0025 0.0165 0.0368
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0238 0.2907 0.751
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0165 0.6196
Schistosoma mansoni ap endonuclease 0.0021 0.0102 0.0066
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0033 0.026 0.0239
Mycobacterium tuberculosis Probable lipase LipE 0.0039 0.0344 0.035
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0039 0.0344 0.035
Toxoplasma gondii histone lysine methyltransferase SET1 0.0058 0.0591 0.2374
Brugia malayi CXXC zinc finger family protein 0.0029 0.021 0.0487
Trichomonas vaginalis set domain proteins, putative 0.027 0.333 0.8582
Brugia malayi PHD-finger family protein 0.0033 0.0266 0.0632
Giardia lamblia Fructose-bisphosphate aldolase 0.0286 0.3529 1
Echinococcus granulosus PHD finger protein rhinoceros 0.0033 0.0266 0.0245
Echinococcus multilocularis mitogen activated protein kinase 3 0.0051 0.05 0.0479
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0035 0.0284 0.0249
Loa Loa (eye worm) hypothetical protein 0.0052 0.0506 0.1257
Brugia malayi MAP kinase sur-1 0.0051 0.05 0.124
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0039 0.0344 0.035
Trypanosoma brucei protein kinase, putative 0.0051 0.05 1
Loa Loa (eye worm) hypothetical protein 0.0039 0.0344 0.0836
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0344 0.0644
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0165 0.0305
Schistosoma mansoni aldehyde dehydrogenase 0.018 0.2164 0.2135
Loa Loa (eye worm) hypothetical protein 0.0045 0.0413 0.1014
Mycobacterium tuberculosis Conserved protein 0.0039 0.0344 0.035
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0019 0.0086 0.005
Schistosoma mansoni cpg binding protein 0.0029 0.021 0.0175
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0344 0.665
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0024 0.0151 0.013
Onchocerca volvulus 0.027 0.333 1
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0046 0.0432 0.0411
Echinococcus granulosus geminin 0.0193 0.233 0.2313
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0051 0.05 1
Onchocerca volvulus 0.0039 0.0344 0.0429
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0165 0.2779
Toxoplasma gondii aldehyde dehydrogenase 0.018 0.2164 1
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0036 0.0304 0.0283
Schistosoma mansoni microtubule-associated protein tau 0.0787 1 1
Leishmania major hypothetical protein, conserved 0.0039 0.0344 0.1449
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0021 0.0102 0.0205
Schistosoma mansoni zinc finger protein 0.0021 0.0113 0.0077
Mycobacterium tuberculosis Probable lipase LipD 0.0039 0.0344 0.035
Giardia lamblia Kinase, CMGC MAPK 0.0051 0.05 0.116
Mycobacterium leprae Probable UDP-galactopyranose mutase Glf (UDP-galp mutase) (NAD+-flavin adenine dinucleotide-requiring enzyme) 0.0557 0.7032 1
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0042 0.0382 0.0347
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0165 0.2779
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0033 0.0266 0.0231
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.05 0.1057
Leishmania major hypothetical protein, conserved 0.0025 0.0165 0.0605
Loa Loa (eye worm) PHD-finger family protein 0.0033 0.0266 0.0632
Toxoplasma gondii PHD-finger domain-containing protein 0.0033 0.0266 0.0795
Mycobacterium ulcerans aldehyde dehydrogenase 0.018 0.2164 0.2975
Mycobacterium tuberculosis Conserved protein 0.0039 0.0344 0.035
Schistosoma mansoni glutaminase 0.0312 0.3863 0.3841
Echinococcus multilocularis beta LACTamase domain containing family member 0.0039 0.0344 0.0323
Mycobacterium ulcerans hypothetical protein 0.0039 0.0344 0.035
Loa Loa (eye worm) hypothetical protein 0.0041 0.0367 0.0894
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0251 0.3077 0.4294
Echinococcus granulosus jumonji domain containing protein 0.0046 0.0434 0.0413
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0051 0.05 1
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0109 0.1242 0.1223
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0042 0.0382 0.0361
Loa Loa (eye worm) jmjC domain-containing protein 0.0044 0.0402 0.0987
Schistosoma mansoni aldehyde dehydrogenase 0.018 0.2164 0.2135
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.05 0.1057
Schistosoma mansoni hypothetical protein 0.0193 0.233 0.2302
Echinococcus granulosus cpg binding protein 0.0032 0.0257 0.0235
Echinococcus multilocularis mitogen activated protein kinase 0.0051 0.05 0.0479
Plasmodium vivax SET domain protein, putative 0.0035 0.0284 0.826
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0052 0.0506 0.0472
Loa Loa (eye worm) hypothetical protein 0.0057 0.0572 0.143
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0017 0.0059 0.0037
Brugia malayi hypothetical protein 0.0025 0.0165 0.0368
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0286 0.3529 0.9111
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0046 0.0432 0.0411
Loa Loa (eye worm) bromodomain containing protein 0.0018 0.0067 0.0113
Schistosoma mansoni serine/threonine protein kinase 0.0051 0.05 0.0465
Schistosoma mansoni cpg binding protein 0.0032 0.0257 0.0221
Mycobacterium ulcerans glutaminase 0.0312 0.3863 0.5427
Mycobacterium ulcerans aldehyde dehydrogenase 0.018 0.2164 0.2975
Trichomonas vaginalis esterase, putative 0.0039 0.0344 0.0644
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0109 0.1242 0.1223
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0165 0.2779
Plasmodium falciparum phd finger protein, putative 0.0033 0.0266 1
Brugia malayi hypothetical protein 0.0016 0.0049 0.0066
Echinococcus multilocularis jumonji domain containing protein 0.0046 0.0434 0.0413
Echinococcus granulosus mitogen activated protein kinase 0.0051 0.05 0.0479
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0059 0.0023
Toxoplasma gondii PHD-finger domain-containing protein 0.0033 0.0266 0.0795
Echinococcus multilocularis cpg binding protein 0.0032 0.0257 0.0235
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0021 0.0102 0.5
Echinococcus granulosus beta LACTamase domain containing family member 0.0039 0.0344 0.0323
Schistosoma mansoni jumonji/arid domain-containing protein 0.0044 0.0402 0.0368
Onchocerca volvulus 0.0039 0.0344 0.0429
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.05 0.1057
Echinococcus multilocularis zinc finger protein 0.0021 0.0113 0.0091
Brugia malayi Pre-SET motif family protein 0.0238 0.2907 0.751
Loa Loa (eye worm) hypothetical protein 0.0039 0.0336 0.0814
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0286 0.3529 0.9111
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0051 0.05 1
Echinococcus granulosus fetal alzheimer antigen falz 0.0024 0.0151 0.013
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0036 0.0304 0.0283
Mycobacterium ulcerans lipase LipD 0.0039 0.0344 0.035
Schistosoma mansoni hypothetical protein 0.0412 0.5155 0.5138
Brugia malayi Bromodomain containing protein 0.0077 0.0833 0.211
Echinococcus multilocularis geminin 0.0193 0.233 0.2313
Plasmodium vivax hypothetical protein, conserved 0.0039 0.0344 1
Loa Loa (eye worm) beta-lactamase 0.0039 0.0344 0.0836
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0042 0.0382 0.0361
Mycobacterium ulcerans beta-lactamase 0.0039 0.0344 0.035
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0042 0.0382 0.7457
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0051 0.05 0.2179
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0432 0.0397

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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