Detailed information for compound 1246729

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 330.377 | Formula: C22H18O3
  • H donors: 3 H acceptors: 3 LogP: 5.4 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: Oc1cccc(c1)/C=C/c1ccc(cc1)/C=C/c1ccc(c(c1)O)O
  • InChi: 1S/C22H18O3/c23-20-3-1-2-18(14-20)10-8-16-4-6-17(7-5-16)9-11-19-12-13-21(24)22(25)15-19/h1-15,23-25H/b10-8+,11-9+
  • InChiKey: CFVUBIICSYLCEU-GFULKKFKSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0138 0.0186 0.0672
Trichomonas vaginalis CAMK family protein kinase 0.0063 0.0066 0.0203
Echinococcus granulosus phosphatidylinositol 45 bisphosphate 3 kinase 0.0473 0.0722 0.2611
Mycobacterium leprae Probable lipase LipE 0.0182 0.0256 0.5939
Entamoeba histolytica protein kinase domain containing protein 0.175 0.2764 1
Plasmodium vivax hypothetical protein, conserved 0.0036 0.0023 0.0074
Trypanosoma cruzi hypothetical protein, conserved 0.0182 0.0256 0.0919
Plasmodium vivax hypothetical protein, conserved 0.0036 0.0023 0.0074
Schistosoma mansoni jumonji/arid domain-containing protein 0.0241 0.035 0.1266
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0138 0.0186 0.0672
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0036 0.0023 0.0066
Loa Loa (eye worm) hypothetical protein 0.0167 0.0232 0.0838
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0247 0.0361 0.1306
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0473 0.0722 0.2604
Echinococcus multilocularis transient receptor potential gamma protein 0.0097 0.012 0.0435
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0595 0.0916 0.3311
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.0048 0.0042 0.0145
Echinococcus multilocularis phosphatidylinositol 4 phosphate 3 kinase C2 0.0306 0.0455 0.1647
Echinococcus multilocularis GPCR, family 2 0.0049 0.0044 0.0159
Entamoeba histolytica protein kinase, putative 0.175 0.2764 1
Plasmodium vivax glutathione reductase, putative 0.0048 0.0042 0.0144
Trichomonas vaginalis hypothetical protein 0.0036 0.0023 0.0066
Schistosoma mansoni protein kinase 0.0075 0.0085 0.0309
Giardia lamblia Telomerase catalytic subunit 0.1714 0.2706 0.9791
Echinococcus granulosus phosphatidylinositol 4 phosphate 3 kinase C2 0.0306 0.0455 0.1647
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0138 0.0186 0.0672
Giardia lamblia Kinase, CMGC GSK 0.175 0.2764 1
Loa Loa (eye worm) hypothetical protein 0.027 0.0396 0.1434
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0595 0.0916 0.2946
Trichomonas vaginalis chromobox protein, putative 0.0036 0.0023 0.0066
Schistosoma mansoni hypothetical protein 0.0337 0.0505 0.1826
Loa Loa (eye worm) hypothetical protein 0.0023 0.0002 0.0007
Trichomonas vaginalis penicillin-binding protein, putative 0.0182 0.0256 0.0818
Plasmodium vivax heterochromatin protein 1, putative 0.0036 0.0023 0.0074
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0037 0.0025 0.0082
Trichomonas vaginalis phosphatidylinositol 4-kinase, putative 0.0062 0.0064 0.0198
Trichomonas vaginalis CAMK family protein kinase 0.0109 0.014 0.0443
Toxoplasma gondii aurora kinase 0.0075 0.0085 0.0301
Trichomonas vaginalis inositol monophosphatase, putative 0.0072 0.008 0.025
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0376 0.0567 0.2046
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0122 0.0161 0.3705
Onchocerca volvulus 0.0182 0.0256 0.0256
Toxoplasma gondii HEAT repeat-containing protein 0.0032 0.0016 0.0048
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0036 0.0023 0.0066
Brugia malayi MH2 domain containing protein 0.0375 0.0564 0.0777
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0306 0.0455 0.0627
Mycobacterium tuberculosis Putative ferredoxin reductase 0.011 0.0141 0.0763
Brugia malayi PHD-finger family protein 0.0048 0.0042 0.0058
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0155 0.0214 0.0294
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.175 0.2764 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0138 0.0186 0.0672
Loa Loa (eye worm) AUR protein kinase 0.0075 0.0085 0.0309
Mycobacterium tuberculosis Probable hydrolase 0.0182 0.0256 0.1395
Echinococcus multilocularis lysine specific demethylase 5A 0.0241 0.035 0.1266
Brugia malayi Thioredoxin reductase 0.0048 0.0042 0.0058
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0037 0.0025 0.0091
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0037 0.0025 0.0539
Brugia malayi MH2 domain containing protein 0.0026 0.0006 0.0008
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0072 0.008 0.0281
Brugia malayi jmjC domain containing protein 0.0545 0.0837 0.1154
Loa Loa (eye worm) hypothetical protein 0.0247 0.0361 0.1306
Brugia malayi jmjC domain containing protein 0.0064 0.0068 0.0093
Entamoeba histolytica hypothetical protein 0.0026 0.0006 0.0015
Schistosoma mansoni Smad4 0.0026 0.0006 0.0022
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0138 0.0186 0.0672
Loa Loa (eye worm) hypothetical protein 0.0023 0.0002 0.0007
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0036 0.0023 0.0066
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0036 0.0023 0.0066
Schistosoma mansoni hypothetical protein 0.0167 0.0232 0.0839
Loa Loa (eye worm) hypothetical protein 0.0182 0.0256 0.0927
Echinococcus multilocularis phosphatidylinositol 4,5 bisphosphate 3 kinase 0.0473 0.0722 0.2611
Echinococcus granulosus protein kinase shaggy 0.175 0.2764 1
Echinococcus granulosus TRP transient receptor potential channel 0.0036 0.0023 0.0083
Leishmania major GTP-binding protein, putative 0.0023 0.0002 0.0002
Entamoeba histolytica serine/threonine protein kinase, putative 0.0109 0.014 0.0499
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.011 0.0141 0.0763
Brugia malayi Transient-receptor-potential like protein 0.0036 0.0023 0.0032
Echinococcus granulosus phd:f box containing protein 0.0064 0.0068 0.0245
Trichomonas vaginalis CAMK family protein kinase 0.0109 0.014 0.0443
Trichomonas vaginalis CMGC family protein kinase 0.175 0.2764 0.89
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0036 0.0023 0.0066
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0036 0.0023 0.0083
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0473 0.0722 0.2318
Echinococcus granulosus importin subunit beta 1 0.0032 0.0016 0.0057
Giardia lamblia Aurora kinase 0.0075 0.0085 0.0301
Trichomonas vaginalis D-aminoacylase, putative 0.0182 0.0256 0.0818
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0247 0.0361 0.1306
Loa Loa (eye worm) AUR protein kinase 0.0075 0.0085 0.0309
Brugia malayi beta-lactamase 0.0182 0.0256 0.0353
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0064 0.0068 0.0237
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0036 0.0023 0.0066
Schistosoma mansoni protein phosphatase 2C 0.0064 0.0068 0.0245
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0005 0.0009
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0037 0.0025 0.0082
Echinococcus granulosus chromobox protein 2 0.0036 0.0023 0.0083
Trichomonas vaginalis AGC family protein kinase 0.0075 0.0085 0.0268
Entamoeba histolytica hypothetical protein 0.0036 0.0023 0.0076
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0158 0.0218 0.0782
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0595 0.0916 0.3311
Trichomonas vaginalis chromobox protein, putative 0.0221 0.0318 0.1017
Echinococcus multilocularis peregrin 0.0148 0.0201 0.0729
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0062 0.0064 0.0198
Schistosoma mansoni jumonji domain containing protein 0.0446 0.0678 0.2455
Schistosoma mansoni ap endonuclease 0.0037 0.0025 0.0091
Entamoeba histolytica hypothetical protein 0.0036 0.0023 0.0076
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0026 0.0006 0.0012
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0545 0.0837 0.303
Loa Loa (eye worm) hypothetical protein 0.0124 0.0163 0.0589
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0064 0.0067 0.0243
Loa Loa (eye worm) glutathione reductase 0.0048 0.0042 0.0153
Schistosoma mansoni smad1 5 8 and 0.0026 0.0006 0.0022
Leishmania major protein kinase, putative 0.0075 0.0085 0.0302
Echinococcus granulosus jumonji domain containing protein 0.0206 0.0294 0.1063
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0325 0.0485 0.1554
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.011 0.0141 0.0763
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0064 0.0068 0.0245
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0247 0.0361 0.1306
Trichomonas vaginalis CAMK family protein kinase 0.0109 0.014 0.0443
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0109 0.014 0.0506
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0036 0.0023 0.0066
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0158 0.0218 0.0696
Trypanosoma cruzi telomerase reverse transcriptase, putative 0.1714 0.2706 0.9791
Brugia malayi serine/threonine-protein kinase 6 0.0075 0.0085 0.0118
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0037 0.0025 0.0127
Giardia lamblia PHD finger protein 15 0.0148 0.0201 0.072
Echinococcus granulosus histone lysine methyltransferase setb 0.0247 0.0361 0.1306
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0005 0.0009
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0545 0.0837 0.303
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0036 0.0023 0.0066
Echinococcus multilocularis microtubule associated protein 2 0.0669 0.1035 0.3745
Echinococcus multilocularis snurportin 1 0.0337 0.0505 0.1826
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0138 0.0186 0.0672
Schistosoma mansoni hypothetical protein 0.0077 0.0089 0.0322
Schistosoma mansoni ran 0.0023 0.0002 0.0009
Echinococcus granulosus PHD finger protein rhinoceros 0.0148 0.0201 0.0729
Loa Loa (eye worm) hypothetical protein 0.0182 0.0256 0.0927
Brugia malayi Latrophilin receptor protein 2 0.0049 0.0044 0.006
Echinococcus multilocularis chromobox protein 2 0.0036 0.0023 0.0083
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0144 0.0196 0.07
Schistosoma mansoni inositol monophosphatase 0.0072 0.008 0.0289
Echinococcus granulosus phosphatidylinositol 3 kinase catalytic subunit 0.0062 0.0064 0.0231
Loa Loa (eye worm) hypothetical protein 0.0048 0.0042 0.0153
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0473 0.0722 0.2604
Echinococcus granulosus Chromo domain 0.0036 0.0023 0.0083
Brugia malayi M-phase phosphoprotein, mpp8 0.0036 0.0023 0.0032
Loa Loa (eye worm) hypothetical protein 0.0306 0.0455 0.1647
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0002 0.0003
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0062 0.0064 0.0198
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0005 0.0009
Loa Loa (eye worm) jmjC domain-containing protein 0.0305 0.0453 0.1638
Brugia malayi MH1 domain containing protein 0.0026 0.0006 0.0008
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0337 0.0505 0.1826
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0158 0.0218 0.0696
Plasmodium falciparum heterochromatin protein 1 0.0036 0.0023 0.0074
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0036 0.0023 0.0076
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0062 0.0064 0.0231
Trypanosoma cruzi hypothetical protein, conserved 0.0182 0.0256 0.0919
Entamoeba histolytica hypothetical protein 0.0077 0.0089 0.0315
Trichomonas vaginalis AGC family protein kinase 0.0075 0.0085 0.0268
Echinococcus granulosus TGF beta signal transducer SmadC 0.0026 0.0006 0.0022
Schistosoma mansoni hypothetical protein 0.0049 0.0044 0.0159
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0182 0.0256 0.1395
Trichomonas vaginalis penicillin-binding protein, putative 0.0182 0.0256 0.0818
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0036 0.0023 0.0074
Toxoplasma gondii exonuclease III APE 0.0037 0.0025 0.0082
Trypanosoma brucei trypanothione reductase 0.0048 0.0042 0.0144
Onchocerca volvulus 0.0182 0.0256 0.0256
Onchocerca volvulus 0.0097 0.012 0.012
Plasmodium vivax JmjC domain containing protein 0.0064 0.0068 0.0237
Plasmodium falciparum phosphatidylinositol 3-kinase 0.0062 0.0064 0.0222
Entamoeba histolytica phosphatidylinositol 4-kinase, putative 0.0062 0.0064 0.0224
Echinococcus granulosus aurora kinase A 0.0075 0.0085 0.0309
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0064 0.0068 0.0362
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0595 0.0916 0.2946
Loa Loa (eye worm) MH2 domain-containing protein 0.0026 0.0006 0.0022
Brugia malayi intracellular kinase 0.175 0.2764 0.3807
Loa Loa (eye worm) hypothetical protein 0.0061 0.0063 0.0227
Echinococcus granulosus jumonji domain containing 1A 0.0064 0.0068 0.0245
Loa Loa (eye worm) hypothetical protein 0.0049 0.0044 0.0159
Loa Loa (eye worm) phosphatidylinositol 3 0.0144 0.0196 0.0709
Schistosoma mansoni importin beta-1 0.0032 0.0016 0.0057
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0291 0.043 1
Loa Loa (eye worm) hypothetical protein 0.0182 0.0256 0.0927
Loa Loa (eye worm) hypothetical protein 0.0025 0.0005 0.0018
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0062 0.0064 0.0222
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0155 0.0214 0.0773
Onchocerca volvulus 0.0036 0.0023 0.0023
Schistosoma mansoni chromobox protein 0.0221 0.0318 0.115
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0075 0.0085 0.0309
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0325 0.0485 0.1554
Echinococcus multilocularis chromobox protein 1 0.0221 0.0318 0.115
Loa Loa (eye worm) hypothetical protein 0.0064 0.0068 0.0245
Plasmodium vivax glycogen synthase kinase 3, putative 0.175 0.2764 1
Trypanosoma cruzi phosphatidylinositol 3-kinase vps34-like 0.0158 0.0218 0.0782
Leishmania major phosphatidylinositol 4-kinase alpha, putative 0.0062 0.0064 0.0224
Loa Loa (eye worm) hypothetical protein 0.0032 0.0016 0.0057
Loa Loa (eye worm) thioredoxin reductase 0.0048 0.0042 0.0153
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0036 0.0023 0.0083
Brugia malayi AF-10 protein 0.0048 0.0042 0.0058
Brugia malayi PHD-finger family protein 0.0148 0.0201 0.0277
Entamoeba histolytica hypothetical protein 0.0077 0.0089 0.0315
Onchocerca volvulus 0.0036 0.0023 0.0023
Trypanosoma cruzi aurora B kinase, putative 0.0075 0.0085 0.0301
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0023 0.0066
Leishmania major hypothetical protein, conserved 0.0182 0.0256 0.092
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0595 0.0916 0.2946
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0072 0.008 0.025
Echinococcus granulosus phosphatidylinositol 4 kinase alpha 0.0062 0.0064 0.0231
Brugia malayi serine/threonine kinase 12 0.0075 0.0085 0.0118
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0238 0.0346 0.1253
Schistosoma mansoni hypothetical protein 0.0049 0.0044 0.0159
Loa Loa (eye worm) transcription factor SMAD2 0.0375 0.0564 0.2042
Schistosoma mansoni hypothetical protein 0.0049 0.0044 0.0159
Echinococcus multilocularis PHD finger protein rhinoceros 0.0148 0.0201 0.0729
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0023 0.0066
Toxoplasma gondii PHD-finger domain-containing protein 0.0148 0.0201 0.072
Loa Loa (eye worm) helicase 0.0036 0.0023 0.0083
Leishmania major phosphatidylinositol 3-kinase, putative 0.0062 0.0064 0.0224
Loa Loa (eye worm) hypothetical protein 0.0036 0.0023 0.0083
Trypanosoma brucei polo-like protein kinase 0.0109 0.014 0.0497
Loa Loa (eye worm) CHromoDomain protein family member 0.0036 0.0023 0.0083
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0072 0.008 0.0282
Loa Loa (eye worm) jmjC domain-containing protein 0.0241 0.035 0.1266
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0062 0.0064 0.0231
Toxoplasma gondii aldehyde dehydrogenase 0.0064 0.0067 0.0235
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0036 0.0023 0.0074
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0064 0.0068 0.1542
Trypanosoma brucei protein kinase, putative 0.175 0.2764 1
Loa Loa (eye worm) hypothetical protein 0.0036 0.0023 0.0083
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0037 0.0025 0.0082
Echinococcus granulosus short transient receptor potential channel 6 0.0064 0.0068 0.0245
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0036 0.0023 0.0076
Trichomonas vaginalis CAMK family protein kinase 0.0109 0.014 0.0443
Echinococcus multilocularis JmjC domain containing protein 4 0.0064 0.0068 0.0245
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0064 0.0068 0.0245
Onchocerca volvulus Alhambra homolog 0.0148 0.0201 0.0201
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0595 0.0916 0.2946
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.021 0.0301 0.1081
Trichomonas vaginalis conserved hypothetical protein 0.0124 0.0163 0.0517
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0023 0.0002 0.0003
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0037 0.0025 0.0091
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0057 0.0057 0.0206
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0473 0.0722 0.0994
Entamoeba histolytica protein kinase, putative 0.0075 0.0085 0.0302
Entamoeba histolytica hypothetical protein 0.0376 0.0567 0.2046
Trypanosoma brucei telomerase reverse transcriptase 0.1714 0.2706 0.9791
Onchocerca volvulus 0.0284 0.0419 0.0419
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0048 0.0042 0.0145
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0109 0.014 0.0506
Brugia malayi F/Y-rich N-terminus family protein 0.0057 0.0057 0.0078
Echinococcus multilocularis Zinc finger, PHD finger 0.0062 0.0064 0.0231
Plasmodium vivax telomerase reverse transcriptase, putative 0.1714 0.2706 0.9791
Brugia malayi Pre-SET motif family protein 0.1725 0.2724 0.3752
Mycobacterium tuberculosis Conserved protein 0.0182 0.0256 0.1395
Trichomonas vaginalis ap endonuclease, putative 0.0037 0.0025 0.0073
Loa Loa (eye worm) PHD-finger family protein 0.0148 0.0201 0.0729
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0062 0.0064 0.0222
Loa Loa (eye worm) hypothetical protein 0.0182 0.0256 0.0927
Mycobacterium leprae conserved hypothetical protein 0.0182 0.0256 0.5939
Brugia malayi Bromodomain containing protein 0.0148 0.0201 0.0277
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0072 0.008 0.025
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0036 0.0023 0.0083
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0072 0.008 0.0281
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0291 0.043 0.2349
Brugia malayi Calcitonin receptor-like protein seb-1 0.0155 0.0214 0.0294
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0037 0.0025 0.0083
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0473 0.0722 0.2318
Echinococcus granulosus inositol monophosphatase 1 0.0072 0.008 0.0289
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0036 0.0023 0.0074
Trichomonas vaginalis conserved hypothetical protein 0.0088 0.0105 0.0331
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0804 0.1251 0.4528
Trypanosoma brucei importin beta-1 subunit, putative 0.0032 0.0016 0.0048
Brugia malayi hypothetical protein 0.0036 0.0023 0.0032
Trichomonas vaginalis esterase, putative 0.0182 0.0256 0.0818
Brugia malayi glutathione reductase 0.0048 0.0042 0.0058
Loa Loa (eye worm) hypothetical protein 0.0182 0.0256 0.0927
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0291 0.043 1
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0109 0.014 0.0499
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0048 0.0042 0.0221
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0138 0.0186 0.0672
Toxoplasma gondii thioredoxin reductase 0.0048 0.0042 0.0144
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.175 0.2764 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0138 0.0186 0.0672
Mycobacterium tuberculosis Probable lipase LipE 0.0182 0.0256 0.1395
Loa Loa (eye worm) CMGC/GSK protein kinase 0.175 0.2764 1
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0037 0.0025 0.0082
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0072 0.008 0.0282
Onchocerca volvulus 0.175 0.2764 0.2764
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0158 0.0218 0.0301
Echinococcus multilocularis chromobox protein 1 0.0221 0.0318 0.115
Schistosoma mansoni microtubule-associated protein tau 0.0669 0.1035 0.3745
Brugia malayi hypothetical protein 0.0077 0.0089 0.0123
Echinococcus granulosus smad 0.0026 0.0006 0.0022
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.175 0.2764 1
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0023 0.0066
Loa Loa (eye worm) inositol-1 0.0072 0.008 0.0289
Loa Loa (eye worm) latrophilin receptor protein 2 0.0049 0.0044 0.0159
Brugia malayi latrophilin 2 splice variant baaae 0.0106 0.0135 0.0186
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0182 0.0256 0.0927
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0036 0.0023 0.0066
Brugia malayi Protein cec-1. 0.0036 0.0023 0.0032
Onchocerca volvulus 0.0182 0.0256 0.0256
Schistosoma mansoni serine/threonine protein kinase 0.0109 0.014 0.0506
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0075 0.0085 0.0302
Brugia malayi Heterochromatin protein 1 0.0221 0.0318 0.0438
Schistosoma mansoni chromobox protein 0.0036 0.0023 0.0083
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0036 0.0023 0.0083
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0064 0.0068 0.0237
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.011 0.0141 0.0763
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0026 0.0006 0.0022
Entamoeba histolytica hypothetical protein 0.0077 0.0089 0.0315
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0036 0.0023 0.0066
Mycobacterium tuberculosis Possible penicillin-binding protein 0.1162 0.1824 1
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0037 0.0025 0.0082
Entamoeba histolytica protein kinase, putative 0.0075 0.0085 0.0302
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0023 0.0066
Echinococcus granulosus glycogen synthase kinase 3 beta 0.175 0.2764 1
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0182 0.0256 0.0927
Schistosoma mansoni hypothetical protein 0.0106 0.0135 0.0489
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0158 0.0218 0.079
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0138 0.0186 0.0256
Toxoplasma gondii PHD-finger domain-containing protein 0.0048 0.0042 0.0145
Entamoeba histolytica protein kinase , putative 0.0075 0.0085 0.0302
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0036 0.0023 0.0076
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0064 0.0067 0.0358
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0075 0.0085 0.0302
Giardia lamblia Phosphoinositide-3-kinase, catalytic, alpha polypeptide 0.0228 0.033 0.1187
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0158 0.0218 0.0783
Schistosoma mansoni phosphatidylserine receptor 0.0064 0.0068 0.0245
Loa Loa (eye worm) heterochromatin protein 1 0.0221 0.0318 0.115
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.011 0.0141 0.3247
Echinococcus multilocularis short transient receptor potential channel 6 0.0064 0.0068 0.0245
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0037 0.0025 0.0091
Giardia lamblia Fructose-bisphosphate aldolase 0.0595 0.0916 0.331
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0109 0.014 0.0506
Brugia malayi phosphatidylinositol 4-kinase, catalytic, alpha polypeptide 0.0062 0.0064 0.0088
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0002 0.0003
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0473 0.0722 0.2605
Trypanosoma cruzi polo-like protein kinase, putative 0.0109 0.014 0.0497
Loa Loa (eye worm) hypothetical protein 0.0106 0.0135 0.0489
Echinococcus granulosus lysine specific demethylase 6a 0.0064 0.0068 0.0245
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0023 0.0066
Echinococcus granulosus snurportin 1 0.0337 0.0505 0.1826
Plasmodium vivax phosphatidylinositol 3-kinase, putative 0.0062 0.0064 0.0222
Echinococcus multilocularis inositol monophosphatase 1 0.0072 0.008 0.0289
Loa Loa (eye worm) hypothetical protein 0.0023 0.0002 0.0007
Entamoeba histolytica protein kinase domain containing protein 0.0075 0.0085 0.0302
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.175 0.2764 1
Schistosoma mansoni kinase 0.0064 0.0067 0.0244
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0002 0.0003
Plasmodium falciparum JmjC domain-containing protein, putative 0.0064 0.0068 0.0237
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0026 0.0006 0.0022
Schistosoma mansoni hypothetical protein 0.0048 0.0042 0.0153
Echinococcus multilocularis importin subunit beta 1 0.0032 0.0016 0.0057
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0049 0.0044 0.006
Loa Loa (eye worm) hypothetical protein 0.0182 0.0256 0.0927
Trypanosoma cruzi telomerase reverse transcriptase, putative 0.1714 0.2706 0.9791
Mycobacterium tuberculosis Probable dehydrogenase 0.011 0.0141 0.0763
Entamoeba histolytica protein kinase domain containing protein 0.175 0.2764 1
Trichomonas vaginalis D-aminoacylase, putative 0.0182 0.0256 0.0818
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0182 0.0256 0.1395
Trichomonas vaginalis CAMK family protein kinase 0.0063 0.0066 0.0203
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit gamma, putative 0.0473 0.0722 0.2318
Trichomonas vaginalis AGC family protein kinase 0.0075 0.0085 0.0268
Echinococcus granulosus chromobox protein 1 0.0221 0.0318 0.115
Echinococcus multilocularis short transient receptor potential channel 6 0.0064 0.0068 0.0245
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0023 0.0002 0.0009
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0182 0.0256 0.0353
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0148 0.0201 0.0729
Mycobacterium ulcerans aldehyde dehydrogenase 0.0064 0.0067 0.1526
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0158 0.0218 0.0783
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0122 0.0161 0.087
Trichomonas vaginalis CAMK family protein kinase 0.0109 0.014 0.0443
Mycobacterium ulcerans aldehyde dehydrogenase 0.0064 0.0067 0.1526
Brugia malayi jmjC domain containing protein 0.0064 0.0068 0.0093
Loa Loa (eye worm) AUR protein kinase 0.0075 0.0085 0.0309
Echinococcus granulosus GTP binding nuclear protein Ran 0.0023 0.0002 0.0009
Loa Loa (eye worm) beta-lactamase 0.0182 0.0256 0.0927
Echinococcus multilocularis protein kinase shaggy 0.175 0.2764 1
Loa Loa (eye worm) hypothetical protein 0.0036 0.0023 0.0083
Schistosoma mansoni hypothetical protein 0.0049 0.0044 0.0159
Leishmania major importin beta-1 subunit, putative 0.0026 0.0006 0.0015
Mycobacterium ulcerans esterase/lipase LipP 0.0182 0.0256 0.5939
Brugia malayi Pre-SET motif family protein 0.0247 0.0361 0.0497
Trichomonas vaginalis conserved hypothetical protein 0.0088 0.0105 0.0331
Echinococcus multilocularis smad 0.0026 0.0006 0.0022
Mycobacterium tuberculosis Probable oxidoreductase 0.0122 0.0161 0.087
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0124 0.0163 0.0163
Mycobacterium tuberculosis Probable esterase LipL 0.0182 0.0256 0.1395
Plasmodium vivax hypothetical protein, conserved 0.0182 0.0256 0.0919
Trichomonas vaginalis chromobox protein, putative 0.0133 0.0178 0.0566
Echinococcus granulosus GPCR family 2 0.0049 0.0044 0.0159
Echinococcus granulosus JmjC domain containing protein 4 0.0064 0.0068 0.0245
Echinococcus granulosus transient receptor potential gamma protein 0.0097 0.012 0.0435
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0023 0.0002 0.0009
Echinococcus granulosus thioredoxin glutathione reductase 0.0048 0.0042 0.0153
Echinococcus granulosus lysine specific demethylase 5A 0.0241 0.035 0.1266
Trichomonas vaginalis chromobox protein, putative 0.0036 0.0023 0.0066
Giardia lamblia Kinase, CMGC GSK 0.175 0.2764 1
Leishmania major telomerase reverse transcriptase, putative 0.1714 0.2706 0.9791
Loa Loa (eye worm) hypothetical protein 0.0036 0.0023 0.0083
Schistosoma mansoni smad 0.0026 0.0006 0.0022
Trypanosoma brucei hypothetical protein, conserved 0.0182 0.0256 0.0919
Entamoeba histolytica phosphatidylinositol-4,5-bisphosphate 3-kinase, putative 0.0062 0.0064 0.0224
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0036 0.0023 0.0074
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0075 0.0085 0.0309
Loa Loa (eye worm) phosphatidylinositol 3 0.0376 0.0567 0.2052
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0036 0.0023 0.0083
Echinococcus multilocularis phd:f box containing protein 0.0064 0.0068 0.0245
Entamoeba histolytica hypothetical protein 0.0077 0.0089 0.0315
Plasmodium vivax importin-beta 2, putative 0.0032 0.0016 0.0048
Trichomonas vaginalis chromobox protein, putative 0.0133 0.0178 0.0566
Brugia malayi CHD4 protein 0.0036 0.0023 0.0032
Schistosoma mansoni transient receptor potential channel 0.0064 0.0068 0.0245
Brugia malayi RNA, U transporter 1 0.009 0.0109 0.015
Echinococcus granulosus microtubule associated protein 2 0.0669 0.1035 0.3745
Echinococcus granulosus peregrin 0.0148 0.0201 0.0729
Loa Loa (eye worm) hypothetical protein 0.0097 0.012 0.0435
Loa Loa (eye worm) MH2 domain-containing protein 0.0375 0.0564 0.2042
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0247 0.0361 0.1306
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0595 0.0916 0.2946
Schistosoma mansoni jumonji/arid domain-containing protein 0.0241 0.035 0.1266
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0473 0.0722 0.2611
Loa Loa (eye worm) CMGC/GSK protein kinase 0.175 0.2764 1
Brugia malayi MH2 domain containing protein 0.0026 0.0006 0.0008
Trichomonas vaginalis D-aminoacylase, putative 0.0182 0.0256 0.0818
Mycobacterium tuberculosis Conserved protein 0.0182 0.0256 0.1395
Entamoeba histolytica hypothetical protein 0.0036 0.0023 0.0076
Trypanosoma brucei ULK family serine/threonine-protein kinase, putative 0.0024 0.0003 0.0002
Brugia malayi jmjC domain containing protein 0.0064 0.0068 0.0093
Trichomonas vaginalis chromobox protein, putative 0.0036 0.0023 0.0066
Toxoplasma gondii RNA-directed DNA polymerase 0.1714 0.2706 0.9791
Trichomonas vaginalis conserved hypothetical protein 0.0124 0.0163 0.0517
Loa Loa (eye worm) jmjC domain-containing protein 0.0064 0.0068 0.0245
Onchocerca volvulus 0.1964 0.3105 0.3105
Brugia malayi hypothetical protein 0.0025 0.0005 0.0007
Trichomonas vaginalis AGC family protein kinase 0.0075 0.0085 0.0268
Trichomonas vaginalis Heterochromatin protein, putative 0.0036 0.0023 0.0066
Brugia malayi Telomerase reverse transcriptase 0.4561 0.7259 1
Brugia malayi chromobox protein homolog 3 0.0124 0.0163 0.0224
Schistosoma mansoni ran 0.0023 0.0002 0.0009
Schistosoma mansoni hypothetical protein 0.0167 0.0232 0.0839
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0048 0.0042 0.0145
Onchocerca volvulus Serine\/threonine kinase homolog 0.0109 0.014 0.014
Plasmodium falciparum importin beta, putative 0.0032 0.0016 0.0048
Echinococcus granulosus beta LACTamase domain containing family member 0.0182 0.0256 0.0927
Giardia lamblia Kinase, PLK 0.0109 0.014 0.0497
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0062 0.0064 0.0222
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0023 0.0066
Schistosoma mansoni transient receptor potential channel 4 0.0097 0.012 0.0435
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0182 0.0256 0.1395
Loa Loa (eye worm) jmjC domain-containing protein 0.0064 0.0068 0.0245
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0133 0.0178 0.0178
Mycobacterium ulcerans aldehyde dehydrogenase 0.0064 0.0067 0.1526
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0072 0.008 0.0281
Plasmodium falciparum glycogen synthase kinase 3 0.175 0.2764 1
Echinococcus granulosus chromobox protein 1 0.0221 0.0318 0.115
Treponema pallidum fructose-bisphosphate aldolase 0.0595 0.0916 1
Brugia malayi MH1 domain containing protein 0.0026 0.0006 0.0008
Trichomonas vaginalis CAMK family protein kinase 0.0109 0.014 0.0443
Schistosoma mansoni transcription factor LCR-F1 0.0077 0.0089 0.0322
Echinococcus multilocularis beta LACTamase domain containing family member 0.0182 0.0256 0.0927
Leishmania major trypanothione reductase 0.0048 0.0042 0.0146
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0284 0.0419 0.1515
Trichomonas vaginalis CMGC family protein kinase 0.175 0.2764 0.89
Entamoeba histolytica phosphatidylinositol 3-kinase 1, putative 0.0459 0.0699 0.2524
Schistosoma mansoni smad1 5 8 and 0.0026 0.0006 0.0022
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0064 0.0068 0.0237
Echinococcus granulosus short transient receptor potential channel 6 0.0064 0.0068 0.0245
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0049 0.0044 0.0159
Brugia malayi Smad1 0.0026 0.0006 0.0008
Loa Loa (eye worm) hypothetical protein 0.0033 0.0018 0.0064
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0064 0.0068 0.0237
Schistosoma mansoni aldehyde dehydrogenase 0.0064 0.0067 0.0243
Loa Loa (eye worm) hypothetical protein 0.0036 0.0023 0.0083
Mycobacterium tuberculosis Probable lipase LipD 0.0182 0.0256 0.1395
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0062 0.0064 0.0222
Toxoplasma gondii PHD-finger domain-containing protein 0.0148 0.0201 0.072
Echinococcus granulosus transient receptor potential ion channel A 0.0094 0.0115 0.0417
Plasmodium falciparum glutathione reductase 0.0048 0.0042 0.0144
Schistosoma mansoni chromobox protein 0.0036 0.0023 0.0083
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0158 0.0218 0.0696
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0023 0.0066
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0049 0.0044 0.0159
Schistosoma mansoni aldehyde dehydrogenase 0.0064 0.0067 0.0243
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0036 0.0023 0.0083
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0182 0.0256 0.0927
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0072 0.008 0.0281
Echinococcus granulosus geminin 0.0167 0.0232 0.0839
Mycobacterium ulcerans beta-lactamase 0.0182 0.0256 0.5939
Brugia malayi beta-lactamase family protein 0.0182 0.0256 0.0353
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0122 0.0161 0.087
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0037 0.0025 0.0082
Toxoplasma gondii ABC1 family protein 0.0182 0.0256 0.0919
Loa Loa (eye worm) hypothetical protein 0.0036 0.0023 0.0083
Schistosoma mansoni inositol monophosphatase 0.0072 0.008 0.0289
Trichomonas vaginalis ap endonuclease, putative 0.0037 0.0025 0.0073
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0036 0.0023 0.0083
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0595 0.0916 0.2946
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0077 0.0089 0.0322
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0075 0.0085 0.0302
Echinococcus multilocularis phosphatidylinositol 4 kinase alpha 0.0062 0.0064 0.0231
Brugia malayi serine/threonine-protein kinase plk-2 0.0109 0.014 0.0192
Trypanosoma cruzi importin beta-1 subunit, putative 0.0026 0.0006 0.0014
Trichomonas vaginalis chromobox protein, putative 0.0221 0.0318 0.1017
Trypanosoma cruzi polo-like protein kinase, putative 0.0109 0.014 0.0497
Schistosoma mansoni phd/f-box containing protein 0.0064 0.0068 0.0245
Brugia malayi exodeoxyribonuclease III family protein 0.0037 0.0025 0.0035
Loa Loa (eye worm) hypothetical protein 0.0148 0.0201 0.0729
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0049 0.0044 0.0159
Schistosoma mansoni serine/threonine protein kinase 0.0075 0.0085 0.0309
Echinococcus multilocularis transient receptor potential ion channel A 0.0094 0.0115 0.0417
Loa Loa (eye worm) hypothetical protein 0.0097 0.012 0.0435
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0048 0.0042 0.0145
Plasmodium falciparum telomerase reverse transcriptase 0.1714 0.2706 0.9791
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0036 0.0023 0.0083
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0036 0.0023 0.0066
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0005 0.0009
Echinococcus granulosus mothers against decapentaplegic 5 0.0026 0.0006 0.0022
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0064 0.0068 0.0237
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0064 0.0067 0.0236
Plasmodium vivax thioredoxin reductase, putative 0.0048 0.0042 0.0144
Brugia malayi beta-lactamase family protein 0.0182 0.0256 0.0353
Entamoeba histolytica Ran family GTPase 0.0023 0.0002 0.0002
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0049 0.0044 0.0159
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0064 0.0067 0.0243
Loa Loa (eye worm) hypothetical protein 0.0036 0.0023 0.0083
Schistosoma mansoni hypothetical protein 0.0148 0.0201 0.0729
Plasmodium vivax hypothetical protein, conserved 0.0148 0.0201 0.072
Loa Loa (eye worm) MH1 domain-containing protein 0.0026 0.0006 0.0022
Leishmania major hypothetical protein, conserved 0.0025 0.0005 0.0011
Mycobacterium ulcerans lipase LipD 0.0182 0.0256 0.5939
Trypanosoma brucei importin beta-1 subunit, putative 0.0032 0.0016 0.0048
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.175 0.2764 1
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0023 0.0066
Brugia malayi Inositol-1 0.0072 0.008 0.011
Onchocerca volvulus 0.0023 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0064 0.0068 0.0245
Brugia malayi Importin beta-1 subunit 0.0032 0.0016 0.0022
Echinococcus multilocularis geminin 0.0167 0.0232 0.0839
Mycobacterium tuberculosis Probable reductase 0.011 0.0141 0.0763
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0036 0.0023 0.0083
Brugia malayi Valyl-tRNA synthetase 0.0036 0.0023 0.0032
Schistosoma mansoni transient receptor potential channel 0.0097 0.012 0.0435
Loa Loa (eye worm) Smad1 0.0026 0.0006 0.0022
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0072 0.008 0.1823
Trypanosoma brucei phosphatidylinositol 4-kinase alpha, putative 0.0062 0.0064 0.0222
Echinococcus multilocularis Smad4 0.0026 0.0006 0.0022
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0026 0.0006 0.0012
Brugia malayi jmjC domain containing protein 0.0064 0.0068 0.0093
Plasmodium falciparum serine/threonine protein kinase, putative 0.0075 0.0085 0.0301
Trichomonas vaginalis CAMK family protein kinase 0.0109 0.014 0.0443
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0064 0.0068 0.0245
Echinococcus multilocularis mothers against decapentaplegic 5 0.0026 0.0006 0.0022
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0036 0.0023 0.0066
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0036 0.0023 0.0032
Trichomonas vaginalis importin beta-1, putative 0.0026 0.0006 0.0012
Schistosoma mansoni transient receptor potential channel 0.0064 0.0068 0.0245
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0072 0.008 1
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0005 0.0009
Loa Loa (eye worm) jmjC domain-containing protein 0.0064 0.0068 0.0245
Trypanosoma cruzi trypanothione reductase, putative 0.0048 0.0042 0.0144
Trypanosoma brucei aurora B kinase 0.0075 0.0085 0.0301
Schistosoma mansoni hypothetical protein 0.0036 0.0023 0.0083
Plasmodium vivax hypothetical protein, conserved 0.0048 0.0042 0.0145
Echinococcus multilocularis Chromo domain 0.0036 0.0023 0.0083
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0247 0.0361 0.1298
Schistosoma mansoni jumonji domain containing protein 0.0064 0.0068 0.0245
Schistosoma mansoni smad1 5 8 and 0.0026 0.0006 0.0022
Schistosoma mansoni ap endonuclease 0.0037 0.0025 0.0091
Echinococcus multilocularis jumonji domain containing protein 0.0206 0.0294 0.1063
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0182 0.0256 0.5939
Echinococcus multilocularis Chromobox protein 3 0.0036 0.0023 0.0083
Loa Loa (eye worm) hypothetical protein 0.0155 0.0214 0.0773
Brugia malayi Associated with TFs and helicases family protein 0.0036 0.0023 0.0032
Loa Loa (eye worm) hypothetical protein 0.0036 0.0023 0.0083
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0595 0.0916 0.2946
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0023 0.0066
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0077 0.0089 0.0322
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0247 0.0361 0.1306
Leishmania major hypothetical protein, conserved 0.0064 0.0068 0.0238
Mycobacterium ulcerans hypothetical protein 0.0182 0.0256 0.5939
Echinococcus multilocularis jumonji domain containing 1A 0.0064 0.0068 0.0245
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0005 0.0009
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0005 0.0009
Echinococcus granulosus Chromobox protein 3 0.0036 0.0023 0.0083
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0037 0.0025 0.0083
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0075 0.0085 0.0301
Schistosoma mansoni chromobox protein 0.0221 0.0318 0.115
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0036 0.0023 0.0074
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0036 0.0023 0.0066
Plasmodium falciparum phd finger protein, putative 0.0148 0.0201 0.072
Echinococcus multilocularis aurora kinase A 0.0075 0.0085 0.0309
Mycobacterium tuberculosis Conserved protein 0.0182 0.0256 0.1395
Giardia lamblia Phosphoinositide-3-kinase, class 3 0.0111 0.0142 0.0506
Brugia malayi SET domain containing protein 0.0045 0.0038 0.0052
Echinococcus multilocularis lysine specific demethylase 6a 0.0064 0.0068 0.0245
Brugia malayi jmjC domain containing protein 0.0241 0.035 0.0482
Loa Loa (eye worm) phosphatidylinositol 4-kinase type 3 alpha isoform 1 0.0062 0.0064 0.0231
Brugia malayi serine/threonine protein kinase 6 0.0075 0.0085 0.0118
Echinococcus granulosus Smad4 0.0026 0.0006 0.0022
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0595 0.0916 0.2946
Plasmodium vivax SET domain protein, putative 0.0247 0.0361 0.1298
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.1725 0.2724 0.9856
Plasmodium falciparum thioredoxin reductase 0.0048 0.0042 0.0144
Trichomonas vaginalis set domain proteins, putative 0.1964 0.3105 1
Echinococcus multilocularis thioredoxin glutathione reductase 0.0048 0.0042 0.0153

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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