Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0058 | 0.0532 | 0.0532 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0037 | 0.0259 | 0.0008 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0266 | 0.0473 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0037 | 0.0259 | 0.4216 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0018 | 0.0024 | 0.0017 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.002 | 0.0044 | 0.0053 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.002 | 0.0044 | 0.0079 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0037 | 0.0259 | 0.0259 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0041 | 0.0312 | 0.6086 |
Schistosoma mansoni | hypothetical protein | 0.0018 | 0.0024 | 0.0121 |
Mycobacterium ulcerans | extragenic suppressor protein SuhB | 0.0041 | 0.0312 | 0.0224 |
Loa Loa (eye worm) | bromodomain containing protein | 0.0017 | 0.0008 | 0.0014 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.002 | 0.0044 | 0.0079 |
Brugia malayi | nuclear receptor NHR-88 | 0.002 | 0.0044 | 0.0053 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0041 | 0.0312 | 0.6086 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0039 | 0.0285 | 0.3583 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0049 | 0.0423 | 0.0692 |
Schistosoma mansoni | ap endonuclease | 0.0039 | 0.0285 | 0.1418 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.002 | 0.0044 | 0.0044 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0059 | 0.0545 | 0.1131 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0037 | 0.0259 | 0.4216 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0024 | 0.0043 |
Onchocerca volvulus | 0.0037 | 0.0259 | 1 | |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0018 | 0.0024 | 0.0024 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0044 | 0.0079 |
Toxoplasma gondii | CMGC kinase, MAPK family (ERK) MAPK-1 | 0.0049 | 0.0423 | 0.1139 |
Brugia malayi | Bromodomain containing protein | 0.0073 | 0.0723 | 0.1263 |
Loa Loa (eye worm) | hypothetical protein | 0.0069 | 0.0669 | 0.1191 |
Brugia malayi | hypothetical protein | 0.0027 | 0.014 | 0.0223 |
Echinococcus multilocularis | inositol monophosphatase 1 | 0.0041 | 0.0312 | 0.0312 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0058 | 0.0532 | 0.0947 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0018 | 0.0024 | 0.0043 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0454 | 0.562 | 0.562 |
Loa Loa (eye worm) | PHD-finger family protein | 0.002 | 0.0045 | 0.0079 |
Echinococcus multilocularis | mitogen activated protein kinase | 0.0049 | 0.0423 | 0.0423 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0044 | 0.0079 |
Echinococcus multilocularis | geminin | 0.0173 | 0.2008 | 0.2008 |
Echinococcus granulosus | zinc finger protein | 0.0019 | 0.0031 | 0.0056 |
Schistosoma mansoni | thyroid hormone receptor | 0.002 | 0.0044 | 0.0222 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0049 | 0.0423 | 0.0692 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0049 | 0.0423 | 0.2106 |
Schistosoma mansoni | bromodomain containing protein | 0.0061 | 0.0577 | 0.2872 |
Schistosoma mansoni | inositol monophosphatase | 0.0041 | 0.0312 | 0.1554 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0319 | 0.0568 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0018 | 0.0024 | 0.0043 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0049 | 0.0423 | 1 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.002 | 0.0044 | 0.0079 |
Echinococcus granulosus | inositol monophosphatase 1 | 0.0041 | 0.0312 | 0.0555 |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.0041 | 0.0312 | 0.0693 |
Schistosoma mansoni | inositol monophosphatase | 0.0041 | 0.0312 | 0.1554 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0037 | 0.0259 | 0.0008 |
Schistosoma mansoni | hypothetical protein | 0.002 | 0.0045 | 0.0222 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0037 | 0.0259 | 0.129 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.002 | 0.0044 | 0.0079 |
Echinococcus granulosus | muscleblind protein | 0.0454 | 0.562 | 1 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0037 | 0.0259 | 0.4216 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0037 | 0.0259 | 0.129 |
Schistosoma mansoni | zinc finger protein | 0.0019 | 0.0031 | 0.0157 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.002 | 0.0044 | 0.0053 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0037 | 0.0259 | 0.0008 |
Mycobacterium tuberculosis | Conserved protein | 0.0037 | 0.0259 | 0.0008 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.002 | 0.0044 | 0.0222 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.002 | 0.0044 | 0.0053 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0044 | 0.0079 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0018 | 0.0024 | 0.0043 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.002 | 0.0044 | 0.0053 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.002 | 0.0044 | 0.0053 |
Schistosoma mansoni | ap endonuclease | 0.0039 | 0.0285 | 0.1418 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0059 | 0.0545 | 0.1629 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.002 | 0.0044 | 0.0053 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.002 | 0.0044 | 0.0222 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.002 | 0.0044 | 0.0222 |
Echinococcus multilocularis | mitogen activated protein kinase 3 | 0.0049 | 0.0423 | 0.0423 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.002 | 0.0044 | 0.0222 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.002 | 0.0044 | 0.0222 |
Schistosoma mansoni | hypothetical protein | 0.0173 | 0.2008 | 1 |
Wolbachia endosymbiont of Brugia malayi | enoyl-ACP reductase | 0.0221 | 0.2626 | 1 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0059 | 0.0545 | 0.2713 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.002 | 0.0044 | 0.0079 |
Toxoplasma gondii | ABC1 family protein | 0.0037 | 0.0259 | 0.048 |
Mycobacterium leprae | Probable lipase LipE | 0.0037 | 0.0259 | 0.0008 |
Trypanosoma cruzi | mitogen activated protein kinase 4, putative | 0.0049 | 0.0423 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0295 | 0.0526 |
Echinococcus granulosus | geminin | 0.0173 | 0.2008 | 0.3572 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0039 | 0.0285 | 0.0109 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0044 | 0.0079 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0049 | 0.0423 | 0.0692 |
Loa Loa (eye worm) | hypothetical protein | 0.0058 | 0.0536 | 0.0955 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0059 | 0.0545 | 0.1207 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0039 | 0.0285 | 0.0584 |
Loa Loa (eye worm) | hypothetical protein | 0.0454 | 0.562 | 1 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0039 | 0.0285 | 0.5 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0059 | 0.0545 | 0.1207 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.002 | 0.0044 | 0.0044 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.002 | 0.0044 | 0.0053 |
Loa Loa (eye worm) | CMGC/MAPK/ERK1 protein kinase | 0.0049 | 0.0423 | 0.0752 |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.0041 | 0.0312 | 0.6086 |
Echinococcus multilocularis | GPCR, family 2 | 0.0018 | 0.0024 | 0.0024 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0037 | 0.0259 | 0.0461 |
Brugia malayi | nuclear hormone receptor | 0.002 | 0.0044 | 0.0053 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.0039 | 0.0285 | 0.0109 |
Echinococcus granulosus | mitogen activated protein kinase 3 | 0.0049 | 0.0423 | 0.0752 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0058 | 0.0536 | 0.0931 |
Loa Loa (eye worm) | hypothetical protein | 0.0454 | 0.562 | 1 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.002 | 0.0044 | 0.0044 |
Echinococcus granulosus | GPCR family 2 | 0.0018 | 0.0024 | 0.0043 |
Mycobacterium tuberculosis | NADH-dependent enoyl-[acyl-carrier-protein] reductase InhA (NADH-dependent enoyl-ACP reductase) | 0.0221 | 0.2626 | 0.9313 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0259 | 0.0461 |
Chlamydia trachomatis | enoyl-acyl-carrier protein reductase | 0.0221 | 0.2626 | 0.5 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0037 | 0.0259 | 0.0008 |
Mycobacterium tuberculosis | Conserved protein | 0.0037 | 0.0259 | 0.0008 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0044 | 0.0079 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0037 | 0.0259 | 0.0008 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.002 | 0.0044 | 0.0079 |
Echinococcus multilocularis | FTZ F1 alpha | 0.002 | 0.0044 | 0.0044 |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0041 | 0.0312 | 0.4256 |
Echinococcus multilocularis | muscleblind protein | 0.0454 | 0.562 | 0.562 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.002 | 0.0044 | 0.0079 |
Brugia malayi | Muscleblind-like protein | 0.0454 | 0.562 | 1 |
Mycobacterium leprae | NADH-DEPENDENT ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE INHA (NADH-DEPENDENT ENOYL-ACP REDUCTASE) | 0.0221 | 0.2626 | 1 |
Brugia malayi | MAP kinase sur-1 | 0.0049 | 0.0423 | 0.0728 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0039 | 0.0285 | 0.5124 |
Toxoplasma gondii | enoyl-acyl carrier reductase ENR | 0.0221 | 0.2626 | 1 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0039 | 0.0285 | 0.0109 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.002 | 0.0044 | 0.0079 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0299 | 0.0533 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.002 | 0.0044 | 0.0044 |
Mycobacterium tuberculosis | Conserved protein | 0.0037 | 0.0259 | 0.0008 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0039 | 0.0285 | 0.0584 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0059 | 0.0545 | 0.1207 |
Plasmodium vivax | enoyl-acyl carrier protein reductase | 0.0221 | 0.2626 | 1 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0039 | 0.0285 | 0.0109 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.002 | 0.0044 | 0.0053 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0059 | 0.0545 | 0.2713 |
Brugia malayi | beta-lactamase family protein | 0.0037 | 0.0259 | 0.0436 |
Leishmania major | mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 | 0.0049 | 0.0423 | 0.6993 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.002 | 0.0044 | 0.0079 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.002 | 0.0044 | 0.0222 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.002 | 0.0044 | 0.0079 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.002 | 0.0044 | 0.0053 |
Wolbachia endosymbiont of Brugia malayi | fructose-1,6-bisphosphatase | 0.0041 | 0.0312 | 0.0116 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.002 | 0.0044 | 0.0079 |
Echinococcus granulosus | FTZ F1 alpha | 0.002 | 0.0044 | 0.0079 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0044 | 0.0079 |
Brugia malayi | PHD-finger family protein | 0.0024 | 0.0098 | 0.0149 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0259 | 0.0461 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0022 | 0.0068 | 0.0068 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0059 | 0.0545 | 0.0969 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.002 | 0.0044 | 0.0222 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0041 | 0.0312 | 0.0224 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0049 | 0.0423 | 1 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0039 | 0.0285 | 0.0285 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0044 | 0.0079 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.014 | 0.0248 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0058 | 0.0536 | 0.0931 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0259 | 0.0461 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0037 | 0.0259 | 0.0008 |
Brugia malayi | ecdysteroid receptor | 0.002 | 0.0044 | 0.0053 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0037 | 0.0259 | 0.0008 |
Schistosoma mansoni | coup transcription factor | 0.002 | 0.0044 | 0.0222 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0037 | 0.0259 | 0.0436 |
Brugia malayi | beta-lactamase family protein | 0.0037 | 0.0259 | 0.0436 |
Trichomonas vaginalis | hypothetical protein | 0.0221 | 0.2626 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.002 | 0.0044 | 0.0053 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.002 | 0.0044 | 0.0053 |
Onchocerca volvulus | 0.0037 | 0.0259 | 1 | |
Toxoplasma gondii | exonuclease III APE | 0.0039 | 0.0285 | 0.0584 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0049 | 0.0423 | 0.0692 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.002 | 0.0044 | 0.0044 |
Schistosoma mansoni | nuclear hormone receptor | 0.002 | 0.0044 | 0.0222 |
Mycobacterium ulcerans | enoyl-(acyl carrier protein) reductase | 0.0221 | 0.2626 | 1 |
Onchocerca volvulus | 0.0037 | 0.0259 | 1 | |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.002 | 0.0044 | 0.0079 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0018 | 0.0024 | 0.0017 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0039 | 0.0285 | 0.0507 |
Brugia malayi | beta-lactamase | 0.0037 | 0.0259 | 0.0436 |
Loa Loa (eye worm) | steroid hormone receptor | 0.002 | 0.0044 | 0.0079 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.002 | 0.0044 | 0.0053 |
Trypanosoma brucei | protein kinase, putative | 0.0049 | 0.0423 | 1 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0041 | 0.0312 | 0.0224 |
Leishmania major | mitogen activated protein kinase, putative,map kinase, putative | 0.0049 | 0.0423 | 0.6993 |
Loa Loa (eye worm) | beta-lactamase | 0.0037 | 0.0259 | 0.0461 |
Mycobacterium leprae | conserved hypothetical protein | 0.0037 | 0.0259 | 0.0008 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.002 | 0.0044 | 0.0079 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.004 | 0.0299 | 0.0508 |
Schistosoma mansoni | hypothetical protein | 0.0018 | 0.0024 | 0.0121 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.002 | 0.0044 | 0.0222 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0059 | 0.0545 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0018 | 0.0024 | 0.0121 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0022 | 0.0068 | 0.0122 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.002 | 0.0044 | 0.0053 |
Trypanosoma brucei | mitogen activated protein kinase 4, putative | 0.0049 | 0.0423 | 1 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0018 | 0.0024 | 0.0024 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0235 | 0.2801 | 1 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0039 | 0.0285 | 0.0482 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0044 | 0.0079 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0039 | 0.0285 | 0.5124 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.002 | 0.0044 | 0.0053 |
Schistosoma mansoni | hypothetical protein | 0.0018 | 0.0024 | 0.0121 |
Schistosoma mansoni | hypothetical protein | 0.0173 | 0.2008 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.002 | 0.0044 | 0.0222 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0039 | 0.0285 | 0.5124 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.002 | 0.0044 | 0.0222 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0259 | 0.0461 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.0299 | 0.1491 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0035 | 0.0235 | 0.0419 |
Giardia lamblia | Kinase, CMGC MAPK | 0.0049 | 0.0423 | 1 |
Brugia malayi | steroid hormone receptor | 0.002 | 0.0044 | 0.0053 |
Loa Loa (eye worm) | inositol-1 | 0.0041 | 0.0312 | 0.0555 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.002 | 0.0044 | 0.0053 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0035 | 0.0235 | 0.0235 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0259 | 0.0461 |
Entamoeba histolytica | myo-inositol monophosphatase, putative | 0.0041 | 0.0312 | 1 |
Echinococcus multilocularis | zinc finger protein | 0.0019 | 0.0031 | 0.0031 |
Leishmania major | hypothetical protein, conserved | 0.0037 | 0.0259 | 0.2948 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0037 | 0.0259 | 0.0461 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.0041 | 0.0312 | 0.0224 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0058 | 0.0536 | 0.0955 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.002 | 0.0044 | 0.0044 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.002 | 0.0044 | 0.0079 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0039 | 0.0285 | 0.0507 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.002 | 0.0044 | 0.0053 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0059 | 0.0545 | 0.0545 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.002 | 0.0044 | 0.0044 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0259 | 0.0461 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.002 | 0.0044 | 0.0079 |
Plasmodium falciparum | enoyl-acyl carrier reductase | 0.0221 | 0.2626 | 1 |
Plasmodium vivax | hypothetical protein, conserved | 0.0037 | 0.0259 | 0.048 |
Brugia malayi | Bromodomain containing protein | 0.0037 | 0.0265 | 0.0447 |
Echinococcus granulosus | mitogen activated protein kinase | 0.0049 | 0.0423 | 0.0752 |
Brugia malayi | Inositol-1 | 0.0041 | 0.0312 | 0.053 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.002 | 0.0044 | 0.0044 |
Trypanosoma cruzi | mitogen activated protein kinase 2, putative | 0.0049 | 0.0423 | 1 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0022 | 0.0068 | 0.0341 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
MIC90 (functional) | > 128 ug ml-1 | Antifungal activity against Candida albicans by broth microdilution method | ChEMBL. | 20933407 |
MIC90 (functional) | > 128 ug ml-1 | Antimicrobial activity against Cryptococcus neoformans by broth microdilution method | ChEMBL. | 20933407 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.