Detailed information for compound 1317552

Basic information

Technical information
  • TDR Targets ID: 1317552
  • Name: N-[1-[(4-methylphenyl)methyl]pyrazol-3-yl]-4, 5-dihydrobenzo[g][1,2]benzoxazole-3-carboxami de
  • MW: 384.431 | Formula: C23H20N4O2
  • H donors: 1 H acceptors: 3 LogP: 4.1 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: Cc1ccc(cc1)Cn1ccc(n1)NC(=O)c1noc2c1CCc1c2cccc1
  • InChi: 1S/C23H20N4O2/c1-15-6-8-16(9-7-15)14-27-13-12-20(25-27)24-23(28)21-19-11-10-17-4-2-3-5-18(17)22(19)29-26-21/h2-9,12-13H,10-11,14H2,1H3,(H,24,25,28)
  • InChiKey: SQLGVVYVPYQXBE-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • N-[1-[(4-methylphenyl)methyl]-3-pyrazolyl]-4,5-dihydrobenzo[g][1,2]benzoxazole-3-carboxamide
  • N-[1-(4-methylbenzyl)pyrazol-3-yl]-4,5-dihydrobenzo[g]indoxazene-3-carboxamide
  • MLS000520029
  • IDI1_026164
  • SMR000130444
  • ChemDiv3_008254

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Bacillus subtilis 4'-phosphopantetheinyl transferase ffp Starlite/ChEMBL No references
Homo sapiens nuclear factor, erythroid 2-like 2 Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase Get druggable targets OG5_129301 All targets in OG5_129301
Echinococcus multilocularis L aminoadipate semialdehyde Get druggable targets OG5_129301 All targets in OG5_129301
Onchocerca volvulus Get druggable targets OG5_129301 All targets in OG5_129301
Schistosoma japonicum ko:K00142 aminoadipate-semialdehyde dehydrogenase [EC1.2.1.31], putative Get druggable targets OG5_129301 All targets in OG5_129301
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_129301 All targets in OG5_129301
Echinococcus granulosus L aminoadipate semialdehyde Get druggable targets OG5_129301 All targets in OG5_129301
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase Get druggable targets OG5_129301 All targets in OG5_129301
Cryptosporidium hominis proteinx0005 Get druggable targets OG5_129301 All targets in OG5_129301
Schistosoma japonicum expressed protein Get druggable targets OG5_129301 All targets in OG5_129301
Cryptosporidium parvum phosphopantetheinyl transferase Get druggable targets OG5_129301 All targets in OG5_129301
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Entamoeba histolytica hypothetical protein 4'-phosphopantetheinyl transferase ffp   224 aa 198 aa 28.3 %
Candida albicans aminoadipate-semialdehyde dehydrogenase small subunit 4'-phosphopantetheinyl transferase ffp   224 aa 183 aa 27.3 %
Candida albicans aminoadipate-semialdehyde dehydrogenase small subunit 4'-phosphopantetheinyl transferase ffp   224 aa 183 aa 27.3 %
Trichomonas vaginalis conserved hypothetical protein 4'-phosphopantetheinyl transferase ffp   224 aa 197 aa 22.3 %
Onchocerca volvulus 4'-phosphopantetheinyl transferase ffp   224 aa 186 aa 26.3 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi AKH receptor 0.0248 0.055 0.0686
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0082 0.0087 0.0075
Echinococcus granulosus Tubulin beta 2C chain 0.0091 0.0113 0.0113
Trichomonas vaginalis glucosylceramidase, putative 0.0172 0.0337 0.1827
Echinococcus granulosus endoplasmin 0.0126 0.0209 0.0209
Onchocerca volvulus Bile acid receptor homolog 0.0082 0.0087 0.0706
Trypanosoma cruzi mitochondrial RNA binding complex 1 subunit, putative 0.0074 0.0064 0.0713
Brugia malayi hypothetical protein 0.2142 0.5808 0.7629
Trypanosoma brucei heat shock protein, putative 0.0139 0.0246 0.2737
Echinococcus granulosus neuropeptide Y receptor 0.0248 0.055 0.055
Brugia malayi GnHR receptor homolog 0.0248 0.055 0.0686
Trichomonas vaginalis glucosylceramidase, putative 0.0172 0.0337 0.1827
Toxoplasma gondii PAN/Apple domain-containing protein 0.0116 0.0181 0.0256
Trichomonas vaginalis conserved hypothetical protein 0.0207 0.0435 0.2623
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0224 0.0481 0.2999
Onchocerca volvulus Glucosylceramidase homolog 0.0172 0.0337 0.3472
Brugia malayi hypothetical protein 0.0248 0.055 0.0686
Echinococcus multilocularis rhodopsin orphan GPCR 0.0248 0.055 0.055
Trypanosoma brucei beta tubulin 0.0091 0.0113 0.1254
Onchocerca volvulus 0.0074 0.0064 0.0455
Echinococcus multilocularis SWI:SNF matrix associated 0.0207 0.0435 0.0435
Trypanosoma brucei beta tubulin 0.0091 0.0113 0.1254
Schistosoma mansoni amine GPCR 0.0248 0.055 0.0543
Echinococcus multilocularis neuropeptides capa receptor 0.0248 0.055 0.055
Loa Loa (eye worm) hypothetical protein 0.0248 0.055 0.0686
Schistosoma mansoni protein kinase 0.0137 0.0239 0.0231
Echinococcus multilocularis tubulin subunit beta 0.0091 0.0113 0.0113
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0082 0.0087 0.0087
Onchocerca volvulus 0.0074 0.0064 0.0455
Loa Loa (eye worm) PAN domain-containing protein 0.0116 0.0181 0.0199
Leishmania major heat shock protein 83-1 0.0139 0.0246 0.1454
Loa Loa (eye worm) hypothetical protein 0.0248 0.055 0.0686
Toxoplasma gondii PAN domain-containing protein 0.1799 0.4855 1
Onchocerca volvulus 0.0384 0.0927 1
Loa Loa (eye worm) hypothetical protein 0.011 0.0164 0.0176
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0248 0.055 0.0543
Trichomonas vaginalis conserved hypothetical protein 0.0183 0.0369 0.2084
Brugia malayi follicle stimulating hormone receptor 0.0248 0.055 0.0686
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0109 0.0163 0.0176
Schistosoma mansoni voltage-gated cation channel 0.0158 0.0299 0.0291
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0082 0.0087 0.0087
Trypanosoma cruzi heat shock protein 85, putative 0.0139 0.0246 0.2737
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0535 0.1345 1
Trypanosoma cruzi WLM domain containing protein, putative 0.0074 0.0064 0.0713
Onchocerca volvulus 0.0248 0.055 0.5827
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0248 0.055 0.0543
Entamoeba histolytica heat shock protein 90, putative 0.0139 0.0246 1
Schistosoma mansoni retinoic acid receptor RXR 0.0082 0.0087 0.0078
Leishmania major heat shock protein 83-1 0.0139 0.0246 0.1454
Schistosoma mansoni tubulin subunit beta 0.0091 0.0113 0.0104
Echinococcus granulosus zinc finger protein Ran binding 0.0074 0.0064 0.0064
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0119 0.0189 0.021
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.0367 0.088 0.088
Loa Loa (eye worm) BEN-1 protein 0.0091 0.0113 0.0109
Echinococcus multilocularis SWI:SNF matrix associated 0.0207 0.0435 0.0435
Trichomonas vaginalis glucosylceramidase, putative 0.0262 0.0587 0.3865
Toxoplasma gondii heat shock protein HSP90 0.0139 0.0246 0.039
Trypanosoma brucei Zn-finger in Ran binding protein and others/FYVE zinc finger, putative 0.0074 0.0064 0.0713
Trypanosoma cruzi mitochondrial RNA binding complex 1 subunit, putative 0.0074 0.0064 0.0713
Echinococcus multilocularis rhodopsin orphan GPCR 0.0248 0.055 0.055
Brugia malayi RE15519p 0.0248 0.055 0.0686
Trichomonas vaginalis glucosylceramidase, putative 0.0172 0.0337 0.1827
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0137 0.0239 0.0239
Brugia malayi PAN domain containing protein 0.0116 0.0181 0.0199
Echinococcus multilocularis GPCR, family 2 0.0711 0.1833 0.1833
Toxoplasma gondii beta-1 tubulin, putative 0.0091 0.0113 0.0113
Echinococcus granulosus tachykinin peptides receptor 99D 0.0545 0.1373 0.1373
Schistosoma mansoni hypothetical protein 0.0074 0.0064 0.0056
Brugia malayi putative neuropeptide receptor NPR1 0.0248 0.055 0.0686
Brugia malayi PAN domain containing protein 0.0116 0.0181 0.0199
Schistosoma mansoni nuclear hormone receptor 0.0082 0.0087 0.0078
Leishmania major heat shock protein 83-1 0.0139 0.0246 0.1454
Trypanosoma cruzi WLM domain containing protein, putative 0.0074 0.0064 0.0713
Echinococcus granulosus sodium channel protein 0.0535 0.1345 0.1345
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0082 0.0087 0.0075
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0248 0.055 0.0543
Echinococcus granulosus neuropeptide receptor A26 0.0763 0.1978 0.1978
Leishmania major beta tubulin 0.0091 0.0113 0.0421
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0158 0.0299 0.0299
Mycobacterium ulcerans heat shock protein 90 0.0126 0.0209 1
Trypanosoma brucei beta tubulin 0.0091 0.0113 0.1254
Onchocerca volvulus 0.0082 0.0087 0.0706
Schistosoma mansoni neuropeptide receptor 0.0248 0.055 0.0543
Loa Loa (eye worm) hypothetical protein 0.0116 0.0181 0.0199
Onchocerca volvulus 0.0248 0.055 0.5827
Echinococcus multilocularis neuropeptide receptor 0.0248 0.055 0.055
Echinococcus multilocularis Upstream activation factor subunit UAF30 0.0207 0.0435 0.0435
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0248 0.055 0.055
Loa Loa (eye worm) brahma associated protein 0.0207 0.0435 0.0534
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0082 0.0087 0.0078
Schistosoma mansoni jun-related protein 0.0077 0.0073 0.0065
Loa Loa (eye worm) G-protein coupled receptor 0.0248 0.055 0.0686
Trichomonas vaginalis conserved hypothetical protein 0.0183 0.0369 0.2084
Leishmania major heat shock protein 83-1 0.0139 0.0246 0.1454
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0126 0.0209 1
Onchocerca volvulus 0.0248 0.055 0.5827
Schistosoma mansoni endoplasmin 0.0139 0.0246 0.0238
Brugia malayi Endoplasmin precursor 0.0139 0.0246 0.0284
Trypanosoma brucei heat shock protein, putative 0.0139 0.0246 0.2737
Trypanosoma cruzi Zn-finger in Ran binding protein and others, putative 0.0074 0.0064 0.0713
Trypanosoma cruzi heat shock protein 90, putative 0.0126 0.0209 0.2331
Brugia malayi latrophilin 2 splice variant baaae 0.1426 0.3819 0.5002
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0119 0.0189 0.021
Brugia malayi nuclear hormone receptor 0.0082 0.0087 0.0075
Loa Loa (eye worm) hypothetical protein 0.0248 0.055 0.0686
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0711 0.1833 0.1833
Loa Loa (eye worm) hypothetical protein 0.0248 0.055 0.0686
Echinococcus granulosus sex peptide receptor 0.0248 0.055 0.055
Onchocerca volvulus 0.0116 0.0181 0.1749
Brugia malayi PAN domain containing protein 0.0116 0.0181 0.0199
Brugia malayi hypothetical protein 0.0248 0.055 0.0686
Loa Loa (eye worm) hypothetical protein 0.0248 0.055 0.0686
Echinococcus multilocularis zinc finger protein Ran binding 0.0074 0.0064 0.0064
Schistosoma mansoni hypothetical protein 0.0711 0.1833 0.1829
Trichomonas vaginalis conserved hypothetical protein 0.0183 0.0369 0.2084
Echinococcus granulosus Zinc finger RanBP2 type 0.0074 0.0064 0.0064
Trichomonas vaginalis glucosylceramidase, putative 0.0262 0.0587 0.3865
Echinococcus granulosus Furin 1 0.0224 0.0481 0.0481
Trichomonas vaginalis conserved hypothetical protein 0.0183 0.0369 0.2084
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0248 0.055 0.0543
Leishmania major heat shock protein 83-1 0.0139 0.0246 0.1454
Schistosoma mansoni thyroid hormone receptor 0.0082 0.0087 0.0078
Onchocerca volvulus 0.0248 0.055 0.5827
Echinococcus multilocularis voltage dependent calcium channel 0.0158 0.0299 0.0299
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0082 0.0087 0.0087
Trypanosoma brucei RNA helicase, putative 0.0315 0.0735 0.8192
Loa Loa (eye worm) hypothetical protein 0.0248 0.055 0.0686
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0224 0.0481 0.2999
Toxoplasma gondii Zn-finger in Ran binding protein and others domain-containing protein 0.0074 0.0064 0.0012
Loa Loa (eye worm) hypothetical protein 0.1426 0.3819 0.5002
Brugia malayi G-protein coupled receptor 0.0248 0.055 0.0686
Loa Loa (eye worm) hypothetical protein 0.0248 0.055 0.0686
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0248 0.055 0.0543
Loa Loa (eye worm) hypothetical protein 0.0191 0.039 0.0474
Loa Loa (eye worm) hypothetical protein 0.2788 0.7603 1
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0114 0.0177 0.1968
Schistosoma mansoni TRABID protein (C64 family) 0.0074 0.0064 0.0056
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0114 0.0177 0.1968
Schistosoma mansoni apoptosis regulator bax 0.0367 0.088 0.0873
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0533 0.134 1
Echinococcus multilocularis tumor protein p63 0.0334 0.0788 0.0788
Echinococcus granulosus tissue type plasminogen activator 0.0072 0.0059 0.0059
Brugia malayi Kringle domain containing protein 0.0072 0.0059 0.0037
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0248 0.055 0.0543
Loa Loa (eye worm) hypothetical protein 0.0248 0.055 0.0686
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0074 0.0064 0.0045
Giardia lamblia Furin precursor putative serine protease 0.0183 0.0369 0.4219
Loa Loa (eye worm) hypothetical protein 0.0248 0.055 0.0686
Echinococcus multilocularis serotonin receptor 0.0248 0.055 0.055
Echinococcus granulosus adenylate cyclase type IX 0.0086 0.01 0.01
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0248 0.055 0.0686
Leishmania major heat shock protein 83-1 0.0139 0.0246 0.1454
Onchocerca volvulus 0.0248 0.055 0.5827
Echinococcus granulosus FTZ F1 alpha 0.0082 0.0087 0.0087
Echinococcus granulosus neuropeptides capa receptor 0.0248 0.055 0.055
Echinococcus multilocularis neuropeptide Y receptor 0.0248 0.055 0.055
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0248 0.055 0.0543
Trichomonas vaginalis conserved hypothetical protein 0.0183 0.0369 0.2084
Brugia malayi G protein-coupled receptor F59B2.13 0.0248 0.055 0.0686
Toxoplasma gondii microneme protein MIC17C 0.0116 0.0181 0.0256
Echinococcus multilocularis epidermal growth factor receptor 0.0135 0.0234 0.0234
Trypanosoma cruzi beta tubulin, putative 0.0091 0.0113 0.1254
Leishmania major C-8 sterol isomerase-like protein 0.0373 0.0897 0.6516
Loa Loa (eye worm) hypothetical protein 0.0248 0.055 0.0686
Echinococcus granulosus voltage dependent calcium channel 0.0158 0.0299 0.0299
Echinococcus granulosus allatostatin A receptor 0.0384 0.0927 0.0927
Loa Loa (eye worm) hypothetical protein 0.0116 0.0181 0.0199
Schistosoma mansoni hypothetical protein 0.0077 0.0073 0.0065
Echinococcus granulosus tubulin subunit beta 0.0091 0.0113 0.0113
Brugia malayi hypothetical protein 0.0248 0.055 0.0686
Trichomonas vaginalis conserved hypothetical protein 0.0183 0.0369 0.2084
Schistosoma mansoni hypothetical protein 0.0367 0.088 0.0873
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0082 0.0087 0.0087
Brugia malayi Dopamine receptor 0.0248 0.055 0.0686
Brugia malayi Dopamine receptor protein 1 0.0248 0.055 0.0686
Echinococcus granulosus SWI:SNF matrix associated 0.0207 0.0435 0.0435
Brugia malayi larval opioid receptor 0.0248 0.055 0.0686
Loa Loa (eye worm) hypothetical protein 0.0074 0.0064 0.0045
Leishmania major heat shock protein 83-1 0.0139 0.0246 0.1454
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0248 0.055 0.055
Echinococcus multilocularis g protein coupled receptor 0.0248 0.055 0.055
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0373 0.0897 1
Schistosoma mansoni neuropeptide F-like receptor 0.0248 0.055 0.0543
Echinococcus multilocularis heat shock protein 90 0.0126 0.0209 0.0209
Onchocerca volvulus 0.0248 0.055 0.5827
Entamoeba histolytica protein kinase, putative 0.0109 0.0163 0.3808
Loa Loa (eye worm) hypothetical protein 0.0248 0.055 0.0686
Loa Loa (eye worm) hypothetical protein 0.0082 0.0087 0.0075
Leishmania major beta tubulin 0.0091 0.0113 0.0421
Schistosoma mansoni furin-1 (S08 family) 0.0367 0.0879 0.0873
Echinococcus granulosus neuropeptide s receptor 0.0763 0.1978 0.1978
Loa Loa (eye worm) hypothetical protein 0.0248 0.055 0.0686
Brugia malayi celfurPC protein 0.0676 0.1738 0.2255
Trypanosoma cruzi Zn-finger in Ran binding protein and others, putative 0.0074 0.0064 0.0713
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0248 0.055 0.0543
Echinococcus granulosus g protein coupled receptor 0.0248 0.055 0.055
Trichomonas vaginalis proprotein convertase subtilisin/kexin type, putative 0.0183 0.0369 0.2084
Schistosoma mansoni subfamily S8B unassigned peptidase (S08 family) 0.086 0.2247 0.2244
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0158 0.0299 0.0299
Loa Loa (eye worm) hypothetical protein 0.0248 0.055 0.0686
Leishmania major heat shock protein 83-1 0.0139 0.0246 0.1454
Toxoplasma gondii microneme protein MIC4 0.0116 0.0181 0.0256
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.1363 0.3645 0.3645
Echinococcus multilocularis endoplasmin 0.0126 0.0209 0.0209
Echinococcus granulosus tm gpcr rhodopsin 0.0248 0.055 0.055
Loa Loa (eye worm) hypothetical protein 0.0092 0.0116 0.0112
Brugia malayi neuropeptide F receptor 0.0248 0.055 0.0686
Echinococcus granulosus Upstream activation factor subunit UAF30 0.0207 0.0435 0.0435
Loa Loa (eye worm) hypothetical protein 0.0082 0.0087 0.0075
Giardia lamblia Heat shock protein HSP 90-alpha 0.0126 0.0209 0.1592
Echinococcus granulosus orexin receptor type 2 0.0248 0.055 0.055
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0082 0.0087 0.0075
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0248 0.055 0.0543
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0082 0.0087 0.0078
Loa Loa (eye worm) hypothetical protein 0.0248 0.055 0.0686
Echinococcus granulosus neuropeptide Y receptor 0.0248 0.055 0.055
Plasmodium vivax tubulin beta chain, putative 0.0091 0.0113 0.1439
Loa Loa (eye worm) hypothetical protein 0.0248 0.055 0.0686
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0114 0.0177 0.0919
Brugia malayi Tachykinin-like peptides receptor 99D 0.0469 0.1163 0.1496
Loa Loa (eye worm) hypothetical protein 0.0327 0.0767 0.0972
Echinococcus granulosus neuroendocrine convertase 2 0.055 0.1388 0.1388
Loa Loa (eye worm) hypothetical protein 0.0074 0.0064 0.0045
Brugia malayi neuroendocrine convertase 1 precursor 0.055 0.1388 0.1792
Loa Loa (eye worm) hypothetical protein 0.0248 0.055 0.0686
Loa Loa (eye worm) neuropeptide F receptor 0.0248 0.055 0.0686
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0082 0.0087 0.0087
Echinococcus multilocularis g protein coupled receptor 0.0248 0.055 0.055
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0158 0.0299 0.0299
Trichomonas vaginalis conserved hypothetical protein 0.0183 0.0369 0.2084
Leishmania major heat shock protein 83-1 0.0139 0.0246 0.1454
Onchocerca volvulus Protein ultraspiracle homolog 0.0082 0.0087 0.0706
Schistosoma mansoni hypothetical protein 0.0711 0.1833 0.1829
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0082 0.0087 0.0075
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0114 0.0177 0.0919
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0248 0.055 0.0686
Onchocerca volvulus 0.0248 0.055 0.5827
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0109 0.0163 0.0163
Echinococcus multilocularis sex peptide receptor 0.0248 0.055 0.055
Plasmodium falciparum heat shock protein 90 0.0139 0.0246 0.4974
Loa Loa (eye worm) hypothetical protein 0.0248 0.055 0.0686
Brugia malayi phosphoinositide-dependent protein kinase I 0.0109 0.0163 0.0176
Loa Loa (eye worm) hypothetical protein 0.0248 0.055 0.0686
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0224 0.0481 0.2999
Leishmania major heat shock protein 83-1 0.0139 0.0246 0.1454
Echinococcus granulosus jun protein 0.0095 0.0123 0.0123
Brugia malayi hypothetical protein 0.0248 0.055 0.0686
Chlamydia trachomatis DNA topoisomerase I 0.0207 0.0435 1
Onchocerca volvulus 0.0061 0.0031 0.008
Echinococcus multilocularis voltage dependent calcium channel 0.0158 0.0299 0.0299
Leishmania major beta tubulin 0.0091 0.0113 0.0421
Loa Loa (eye worm) hypothetical protein 0.0367 0.088 0.1121
Trypanosoma cruzi hypothetical protein, conserved 0.0074 0.0064 0.0713
Leishmania major beta tubulin 0.0091 0.0113 0.0421
Echinococcus granulosus hypothetical protein 0.0248 0.055 0.055
Brugia malayi ecdysteroid receptor 0.0082 0.0087 0.0075
Leishmania major heat shock protein 83-1 0.0139 0.0246 0.1454
Onchocerca volvulus 0.01 0.0139 0.1277
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0074 0.0064 0.0045
Brugia malayi PAN domain containing protein 0.0116 0.0181 0.0199
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0082 0.0087 0.0078
Plasmodium falciparum zinc finger Ran-binding domain-containing protein 2, putative 0.0074 0.0064 0.015
Schistosoma mansoni biogenic amine receptor 0.0248 0.055 0.0543
Schistosoma mansoni endoplasmin 0.0139 0.0246 0.0238
Echinococcus multilocularis Tubulin beta 2C chain 0.0091 0.0113 0.0113
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0248 0.055 0.0543
Loa Loa (eye worm) hypothetical protein 0.0082 0.0087 0.0075
Schistosoma mansoni RNA binding protein 0.0074 0.0064 0.0056
Loa Loa (eye worm) hypothetical protein 0.0248 0.055 0.0686
Schistosoma mansoni steroid hormone receptor ad4bp 0.0082 0.0087 0.0078
Echinococcus multilocularis SWI:SNF matrix associated 0.0207 0.0435 0.0435
Toxoplasma gondii PAN domain-containing protein 0.1799 0.4855 1
Echinococcus granulosus Tubulin beta 2C chain 0.0091 0.0113 0.0113
Loa Loa (eye worm) hypothetical protein 0.0116 0.0181 0.0199
Echinococcus granulosus ring and YY1 binding protein 0.0074 0.0064 0.0064
Schistosoma mansoni hypothetical protein 0.0711 0.1833 0.1829
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0248 0.055 0.0686
Schistosoma mansoni opsin-like receptor 0.0248 0.055 0.0543
Loa Loa (eye worm) PAN domain-containing protein 0.0116 0.0181 0.0199
Schistosoma mansoni subfamily S8B non-peptidase homologue (S08 family) 0.0224 0.0481 0.0473
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0137 0.0239 0.0239
Onchocerca volvulus 0.0116 0.0181 0.1749
Trichomonas vaginalis leucine-rich repeat protein, BspA family 0.0183 0.0369 0.2084
Toxoplasma gondii PAN domain-containing protein 0.0116 0.0181 0.0256
Trypanosoma brucei heat shock protein, putative 0.0139 0.0246 0.2737
Schistosoma mansoni histamine h1 receptor 0.0248 0.055 0.0543
Schistosoma mansoni protein kinase 0.0137 0.0239 0.0231
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0126 0.0209 0.5
Leishmania major beta tubulin 0.0091 0.0113 0.0421
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0262 0.0587 0.0735
Trichomonas vaginalis conserved hypothetical protein 0.0183 0.0369 0.2084
Echinococcus multilocularis Nuclear pore complex protein Nup153 0.0074 0.0064 0.0064
Echinococcus granulosus Tubulin beta 2C chain 0.0091 0.0113 0.0113
Plasmodium vivax hypothetical protein, conserved 0.0207 0.0435 1
Leishmania major beta tubulin 0.0091 0.0113 0.0421
Schistosoma mansoni hypothetical protein 0.0248 0.055 0.0543
Leishmania major heat shock protein 83-1 0.0139 0.0246 0.1454
Echinococcus granulosus tubulin beta 4A class IVa 0.0091 0.0113 0.0113
Echinococcus granulosus rhodopsin orphan GPCR 0.0248 0.055 0.055
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0082 0.0087 0.0075
Loa Loa (eye worm) hypothetical protein 0.0116 0.0181 0.0199
Toxoplasma gondii microneme protein MIC17B 0.0116 0.0181 0.0256
Echinococcus multilocularis Furin 1 0.0224 0.0481 0.0481
Echinococcus multilocularis rhodopsin orphan GPCR 0.0248 0.055 0.055
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0082 0.0087 0.0075
Brugia malayi brahma associated protein 60 kDa 0.0207 0.0435 0.0534
Schistosoma mansoni hypothetical protein 0.0207 0.0435 0.0427
Echinococcus multilocularis dro:myosuppressin receptor 0.0248 0.055 0.055
Giardia lamblia Heat shock protein HSP 90-alpha 0.0139 0.0246 0.2193
Trichomonas vaginalis heat shock protein, putative 0.0126 0.0209 0.0786
Brugia malayi hypothetical protein 0.0248 0.055 0.0686
Onchocerca volvulus 0.0248 0.055 0.5827
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0224 0.0481 0.2999
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0248 0.055 0.0543
Schistosoma mansoni biogenic amine (5HT) receptor 0.0248 0.055 0.0543
Brugia malayi endoprotease bli-4 precursor 0.086 0.2247 0.2927
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0114 0.0177 0.1968
Toxoplasma gondii hypothetical protein 0.0116 0.0181 0.0256
Loa Loa (eye worm) hypothetical protein 0.0116 0.0181 0.0199
Schistosoma mansoni amine GPCR 0.0248 0.055 0.0543
Toxoplasma gondii beta-tubulin, putative 0.0091 0.0113 0.0113
Onchocerca volvulus 0.0074 0.0064 0.0455
Echinococcus granulosus rhodopsin orphan GPCR 0.0248 0.055 0.055
Onchocerca volvulus 0.0074 0.0064 0.0455
Toxoplasma gondii hypothetical protein 0.011 0.0164 0.022
Brugia malayi G-protein coupled receptor 0.0248 0.055 0.0686
Onchocerca volvulus 0.0248 0.055 0.5827
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0158 0.0299 0.3332
Echinococcus multilocularis rhodopsin orphan GPCR 0.0248 0.055 0.055
Onchocerca volvulus 0.0116 0.0181 0.1749
Loa Loa (eye worm) hypothetical protein 0.0248 0.055 0.0686
Echinococcus multilocularis Tubulin beta 2C chain 0.0091 0.0113 0.0113
Trichomonas vaginalis conserved hypothetical protein 0.0183 0.0369 0.2084
Brugia malayi hypothetical protein 0.0248 0.055 0.0686
Loa Loa (eye worm) hypothetical protein 0.0082 0.0087 0.0075
Loa Loa (eye worm) BEN-1 protein 0.0091 0.0113 0.0109
Loa Loa (eye worm) endoplasmin 0.0139 0.0246 0.0284
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.3652 1 1
Brugia malayi Dopamine receptor protein 2 0.0248 0.055 0.0686
Brugia malayi putative neuropeptide receptor 0.0248 0.055 0.0686
Brugia malayi ORL1-like opioid receptor 0.0248 0.055 0.0686
Loa Loa (eye worm) tubulin beta-1 chain 0.0091 0.0113 0.0109
Toxoplasma gondii PAN domain-containing protein 0.0116 0.0181 0.0256
Echinococcus granulosus beta tubulin 0.0091 0.0113 0.0113
Toxoplasma gondii beta tubulin 0.0091 0.0113 0.0113
Brugia malayi Latrophilin receptor protein 2 0.0711 0.1833 0.238
Brugia malayi Furin-like cysteine rich region family protein 0.0135 0.0234 0.0269
Brugia malayi Protein kinase domain containing protein 0.0109 0.0163 0.0176
Onchocerca volvulus 0.0116 0.0181 0.1749
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.1363 0.3645 0.3645
Toxoplasma gondii DNA topoisomerase domain-containing protein 0.0207 0.0435 0.0784
Loa Loa (eye worm) hypothetical protein 0.0158 0.0299 0.0355
Loa Loa (eye worm) hypothetical protein 0.0248 0.055 0.0686
Schistosoma mansoni heat shock protein 0.0139 0.0246 0.0238
Loa Loa (eye worm) hypothetical protein 0.2142 0.5808 0.7629
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0082 0.0087 0.0075
Loa Loa (eye worm) hypothetical protein 0.0168 0.0326 0.039
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.01 0.0139 0.013
Loa Loa (eye worm) voltage-dependent calcium channel 0.0158 0.0299 0.0355
Onchocerca volvulus 0.0248 0.055 0.5827
Trypanosoma brucei heat shock protein, putative 0.0139 0.0246 0.2737
Echinococcus granulosus rhodopsin orphan GPCR 0.0248 0.055 0.055
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.0178 0.0353 0.0353
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0248 0.055 0.0543
Leishmania major beta tubulin 0.0091 0.0113 0.0421
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0109 0.0163 0.0163
Schistosoma mansoni biogenic amine receptor 0.0248 0.055 0.0543
Echinococcus granulosus neuropeptide receptor 0.0248 0.055 0.055
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0248 0.055 0.055
Toxoplasma gondii microneme protein, putative 0.0116 0.0181 0.0256
Echinococcus multilocularis fmrfamide receptor 0.0248 0.055 0.055
Trypanosoma brucei Heat shock protein 83, putative 0.0139 0.0246 0.2737
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.01 0.0139 0.0143
Echinococcus granulosus ecdysone induced protein 78C 0.0082 0.0087 0.0087
Trypanosoma cruzi heat shock protein 90, putative 0.0139 0.0246 0.2737
Brugia malayi Serotonin receptor 0.0248 0.055 0.0686
Echinococcus granulosus 7tm_1 domain containing protein 0.0248 0.055 0.055
Onchocerca volvulus 0.0116 0.0181 0.1749
Loa Loa (eye worm) adenylyl cyclase 3 0.0145 0.0263 0.0307
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.2788 0.7603 1
Onchocerca volvulus 0.0116 0.0181 0.1749
Echinococcus granulosus neuropeptide FF receptor 2 0.0469 0.1163 0.1163
Loa Loa (eye worm) hypothetical protein 0.0248 0.055 0.0686
Loa Loa (eye worm) hypothetical protein 0.0074 0.0064 0.0045
Loa Loa (eye worm) hypothetical protein 0.0248 0.055 0.0686
Trypanosoma cruzi heat shock protein 85, putative 0.0139 0.0246 0.2737
Leishmania major beta tubulin 0.0091 0.0113 0.0421
Plasmodium falciparum SWIB/MDM2 domain-containing protein 0.0207 0.0435 1
Echinococcus granulosus Nuclear pore complex protein Nup153 0.0074 0.0064 0.0064
Trypanosoma brucei heat shock protein 90, putative 0.0139 0.0246 0.2737
Echinococcus granulosus tubulin beta 1 chain 0.0091 0.0113 0.0113
Echinococcus multilocularis jun protein 0.0095 0.0123 0.0123
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0248 0.055 0.055
Echinococcus granulosus voltage dependent calcium channel 0.0158 0.0299 0.0299
Echinococcus granulosus anti dorsalizing morphogenetic protein 1a 0.0126 0.0211 0.0211
Echinococcus granulosus furin 0.086 0.2247 0.2247
Echinococcus granulosus rhodopsin orphan GPCR 0.0248 0.055 0.055
Brugia malayi YY1-associated factor 2 0.0074 0.0064 0.0045
Onchocerca volvulus 0.0248 0.055 0.5827
Echinococcus multilocularis allatostatin A receptor 0.0384 0.0927 0.0927
Schistosoma mansoni neuropeptide receptor 0.0248 0.055 0.0543
Schistosoma mansoni heat shock protein 0.0139 0.0246 0.0238
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0248 0.055 0.055
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0248 0.055 0.0543
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.0367 0.088 0.0873
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0082 0.0087 0.0075
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0114 0.0177 0.1968
Echinococcus multilocularis nmda type glutamate receptor 0.0116 0.0182 0.0182
Echinococcus multilocularis orexin receptor type 2 0.0248 0.055 0.055
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0248 0.055 0.0543
Loa Loa (eye worm) hypothetical protein 0.0082 0.0087 0.0075
Trichomonas vaginalis glucosylceramidase, putative 0.0181 0.0363 0.2036
Leishmania major hypothetical protein, conserved 0.0074 0.0064 0.0044
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0082 0.0087 0.0087
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0074 0.0064 0.0045
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0158 0.0299 0.0355
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0082 0.0087 0.0075
Schistosoma mansoni myosin xvIII 0.0248 0.055 0.0543
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0248 0.055 0.055
Trypanosoma brucei heat shock protein, putative 0.0139 0.0246 0.2737
Echinococcus multilocularis tubulin, beta 4A class IVa 0.0091 0.0113 0.0113
Echinococcus granulosus fmrfamide receptor 0.0248 0.055 0.055
Onchocerca volvulus Neuropeptide F receptor homolog 0.0248 0.055 0.5827
Trypanosoma cruzi heat shock protein 85, putative 0.0139 0.0246 0.2737
Loa Loa (eye worm) hypothetical protein 0.0248 0.055 0.0686
Toxoplasma gondii hypothetical protein 0.0116 0.0181 0.0256
Schistosoma mansoni serine/threonine protein kinase 0.0109 0.0163 0.0155
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0158 0.0299 0.0299
Brugia malayi Serotonin receptor 0.0248 0.055 0.0686
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0082 0.0087 0.0087
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0248 0.055 0.0686
Echinococcus multilocularis G protein coupled receptor 139 0.0248 0.055 0.055
Trypanosoma cruzi hypothetical protein, conserved 0.0074 0.0064 0.0713
Loa Loa (eye worm) hypothetical protein 0.0248 0.055 0.0686
Trypanosoma brucei heat shock protein, putative 0.0139 0.0246 0.2737
Brugia malayi hypothetical protein 0.0248 0.055 0.0686
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0248 0.055 0.0686
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0158 0.0299 0.3332
Loa Loa (eye worm) hypothetical protein 0.0248 0.055 0.0686
Echinococcus granulosus dro:myosuppressin receptor 0.0248 0.055 0.055
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0095 0.0123 0.0123
Echinococcus granulosus g protein coupled receptor 0.0248 0.055 0.055
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0248 0.055 0.055
Loa Loa (eye worm) hypothetical protein 0.0384 0.0927 0.1184
Brugia malayi Transforming growth factor beta like domain containing protein 0.0126 0.0211 0.0238
Toxoplasma gondii ran binding protein 0.0074 0.0064 0.0012
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0116 0.0182 0.0182
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.0178 0.0353 0.0426
Schistosoma mansoni serine-type protease inhibitor 0.3645 0.9981 1
Brugia malayi neuropeptide F receptor 0.0248 0.055 0.0686
Echinococcus multilocularis rhodopsin orphan GPCR 0.0248 0.055 0.055
Leishmania major beta tubulin 0.0091 0.0113 0.0421
Echinococcus granulosus rhodopsin orphan GPCR 0.0248 0.055 0.055
Plasmodium vivax heat shock protein 86, putative 0.0139 0.0246 0.4974
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0248 0.055 0.0543
Brugia malayi SWIB/MDM2 domain containing protein 0.0207 0.0435 0.0534
Toxoplasma gondii subtilisin SUB12 0.0156 0.0294 0.049
Loa Loa (eye worm) beta-tubulin 0.0091 0.0113 0.0109
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0109 0.0163 0.0176
Loa Loa (eye worm) PAN domain-containing protein 0.0116 0.0181 0.0199
Echinococcus multilocularis rhodopsin orphan GPCR 0.0248 0.055 0.055
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.1298 0.3465 0.3465
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0082 0.0087 0.0075
Echinococcus granulosus neuropeptide receptor 0.0248 0.055 0.055
Schistosoma mansoni tyrosine kinase 0.0135 0.0234 0.0226
Trichomonas vaginalis neuroendocrine convertase 2 precursor, putative 0.0183 0.0369 0.2084
Echinococcus multilocularis thyroid hormone receptor alpha 0.0082 0.0087 0.0087
Loa Loa (eye worm) hypothetical protein 0.0248 0.055 0.0686
Loa Loa (eye worm) hypothetical protein 0.0248 0.055 0.0686
Schistosoma mansoni neuropeptide receptor 0.0248 0.055 0.0543
Echinococcus granulosus biogenic amine 5HT receptor 0.0248 0.055 0.055
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0126 0.0209 0.0209
Schistosoma mansoni hypothetical protein 0.1426 0.3819 0.382
Loa Loa (eye worm) hypothetical protein 0.0116 0.0181 0.0199
Schistosoma mansoni glutamate receptor NMDA 0.0274 0.0622 0.0615
Trichomonas vaginalis glucosylceramidase, putative 0.0172 0.0337 0.1827
Schistosoma mansoni hypothetical protein 0.0207 0.0435 0.0427
Schistosoma mansoni amine GPCR 0.0248 0.055 0.0543
Echinococcus multilocularis ecdysone induced protein 78C 0.0082 0.0087 0.0087
Echinococcus granulosus tm gpcr rhodopsin 0.1298 0.3465 0.3465
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0248 0.055 0.055
Echinococcus multilocularis Tubulin beta 2C chain 0.0091 0.0113 0.0113
Schistosoma mansoni hypothetical protein 0.0315 0.0735 0.0728
Echinococcus multilocularis heat shock protein 0.0139 0.0246 0.0246
Echinococcus multilocularis adenylate cyclase 9 0.0061 0.0031 0.0031
Loa Loa (eye worm) proprotein convertase 2 0.0224 0.0481 0.0595
Loa Loa (eye worm) hypothetical protein 0.0158 0.0299 0.0355
Onchocerca volvulus 0.0116 0.0181 0.1749
Brugia malayi Calcitonin receptor-like protein seb-1 0.2136 0.5792 0.7608
Loa Loa (eye worm) TK/ROR protein kinase 0.0072 0.0059 0.0037
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0095 0.0123 0.0123
Brugia malayi hypothetical protein 0.0248 0.055 0.0686
Onchocerca volvulus 0.0116 0.0181 0.1749
Trypanosoma cruzi Zn-finger in Ran binding protein and others/FYVE zinc finger, putative 0.0074 0.0064 0.0713
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0126 0.0209 0.5
Schistosoma mansoni coup transcription factor 0.0082 0.0087 0.0078
Schistosoma mansoni hypothetical protein 0.0248 0.055 0.0543
Loa Loa (eye worm) hypothetical protein 0.0248 0.055 0.0686
Schistosoma mansoni hypothetical protein 0.0207 0.0435 0.0427
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0082 0.0087 0.0087
Echinococcus granulosus tm gpcr rhodopsin 0.0248 0.055 0.055
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0248 0.055 0.0543
Loa Loa (eye worm) hypothetical protein 0.0248 0.055 0.0686
Giardia lamblia Grp94/Hsp90 0.0126 0.0209 0.1592
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0248 0.055 0.055
Brugia malayi proprotein convertase 2 0.055 0.1388 0.1792
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0248 0.055 0.0543
Trichomonas vaginalis glucosylceramidase, putative 0.0262 0.0587 0.3865
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0082 0.0087 0.0075
Schistosoma mansoni hypothetical protein 0.0183 0.0369 0.0361
Echinococcus granulosus peptide allatostatin:somatostatin 0.0248 0.055 0.055
Loa Loa (eye worm) hypothetical protein 0.0248 0.055 0.0686
Schistosoma mansoni opsin-like receptor 0.0248 0.055 0.0543
Loa Loa (eye worm) tubulin beta chain 0.0091 0.0113 0.0109
Brugia malayi Steroid receptor seven-up type 2 0.0082 0.0087 0.0075
Schistosoma mansoni tubulin subunit beta 0.0091 0.0113 0.0104
Schistosoma mansoni protein kinase 0.0137 0.0239 0.0231
Schistosoma mansoni neuropeptide f receptor 76f 0.0248 0.055 0.0543
Schistosoma mansoni alpha-1 adrenergic receptor 0.0248 0.055 0.0543
Schistosoma mansoni adenoreceptor 0.0248 0.055 0.0543
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0248 0.055 0.0686
Echinococcus granulosus heat shock protein 0.0139 0.0246 0.0246
Echinococcus multilocularis G-protein coupled receptor, putative 0.0248 0.055 0.055
Trypanosoma brucei mitochondrial RNA binding complex 1 subunit 0.0074 0.0064 0.0713
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0082 0.0087 0.0078
Echinococcus multilocularis 0.0676 0.1738 0.1738
Schistosoma mansoni hypothetical protein 0.0711 0.1833 0.1829
Trypanosoma cruzi Heat shock protein 83, putative 0.0139 0.0246 0.2737
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0074 0.0064 0.0045
Leishmania major beta tubulin 0.0091 0.0113 0.0421
Brugia malayi hypothetical protein 0.0248 0.055 0.0686
Schistosoma mansoni neuropeptide receptor 0.0248 0.055 0.0543
Brugia malayi Tubulin beta-1 chain 0.0091 0.0113 0.0109
Echinococcus multilocularis anti dorsalizing morphogenetic protein 1a 0.0126 0.0211 0.0211
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0114 0.0177 0.1968
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0082 0.0087 0.0075
Loa Loa (eye worm) TYRA-2 protein 0.0248 0.055 0.0686
Echinococcus granulosus nmda type glutamate receptor 0.0116 0.0182 0.0182
Schistosoma mansoni tubulin subunit beta 0.0091 0.0113 0.0104
Echinococcus multilocularis Zinc finger, RanBP2 type 0.0074 0.0064 0.0064
Trichomonas vaginalis glucosylceramidase, putative 0.0262 0.0587 0.3865
Leishmania major beta tubulin 0.0091 0.0113 0.0421
Schistosoma mansoni serine/threonine protein kinase 0.0178 0.0353 0.0345
Leishmania major beta tubulin 0.0091 0.0113 0.0421
Trypanosoma brucei calpain-like protein, putative 0.0114 0.0177 0.1968
Chlamydia trachomatis SWIB complex protein 0.0207 0.0435 1
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0248 0.055 0.055
Loa Loa (eye worm) hypothetical protein 0.01 0.0139 0.0143
Loa Loa (eye worm) hypothetical protein 0.0074 0.0064 0.0045
Onchocerca volvulus Ubiquitin thioesterase ZRANB1 homolog 0.0074 0.0064 0.0455
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0535 0.1345 0.1345
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0082 0.0087 0.0087
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0082 0.0087 0.0706
Brugia malayi PAN domain containing protein 0.0116 0.0181 0.0199
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.0367 0.088 0.1121
Onchocerca volvulus 0.0248 0.055 0.5827
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0158 0.0299 0.0299
Echinococcus multilocularis tubulin beta 1 chain 0.0091 0.0113 0.0113
Echinococcus granulosus adenylate cyclase 9 0.0061 0.0031 0.0031
Leishmania major heat shock protein 83-1 0.0139 0.0246 0.1454
Echinococcus granulosus epidermal growth factor receptor 0.0135 0.0234 0.0234
Trypanosoma cruzi hypothetical protein, conserved 0.0074 0.0064 0.0713
Schistosoma mansoni brg-1 associated factor 0.0207 0.0435 0.0427
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0082 0.0087 0.0075
Loa Loa (eye worm) hypothetical protein 0.0248 0.055 0.0686
Leishmania major beta tubulin 0.0091 0.0113 0.0421
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0158 0.0299 0.0299
Brugia malayi map kinase activated protein kinase protein 2 0.0178 0.0353 0.0426
Onchocerca volvulus 0.0116 0.0181 0.1749
Loa Loa (eye worm) hypothetical protein 0.0373 0.0897 0.1144
Brugia malayi G protein-coupled receptor 0.0248 0.055 0.0686
Trichomonas vaginalis hypothetical protein 0.0183 0.0369 0.2084
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0158 0.0299 0.0291
Schistosoma mansoni tubulin subunit beta 0.0091 0.0113 0.0104
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0114 0.0177 0.0919
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0711 0.1833 0.238
Loa Loa (eye worm) hypothetical protein 0.0074 0.0064 0.0045
Loa Loa (eye worm) hypothetical protein 0.0248 0.055 0.0686
Onchocerca volvulus 0.0071 0.0057 0.0369
Trichomonas vaginalis glucosylceramidase, putative 0.0262 0.0587 0.3865
Echinococcus multilocularis beta tubulin 0.0091 0.0113 0.0113
Loa Loa (eye worm) G-protein coupled receptor 0.0248 0.055 0.0686
Echinococcus multilocularis fmrfamide receptor 0.0248 0.055 0.055
Loa Loa (eye worm) hypothetical protein 0.0082 0.0087 0.0075
Onchocerca volvulus Adenylate cyclase type 3 homolog 0.017 0.0333 0.3426
Brugia malayi bZIP transcription factor family protein 0.0095 0.0123 0.0122
Schistosoma mansoni hypothetical protein 0.0072 0.0059 0.005
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0248 0.055 0.0686
Echinococcus granulosus Tubulin beta 2C chain 0.0091 0.0113 0.0113
Echinococcus multilocularis heat shock protein 90 0.0139 0.0246 0.0246
Echinococcus multilocularis L aminoadipate semialdehyde 0.01 0.0139 0.0139
Echinococcus multilocularis Tubulin beta 2C chain 0.0091 0.0113 0.0113
Loa Loa (eye worm) steroid hormone receptor 0.0082 0.0087 0.0075
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0224 0.0481 0.2999
Toxoplasma gondii PAN domain-containing protein 0.0116 0.0181 0.0256
Brugia malayi brahma associated protein 60 kDa 0.0207 0.0435 0.0534
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.0274 0.0622 0.0622
Brugia malayi sulfakinin receptor protein 0.2142 0.5808 0.7629
Schistosoma mansoni tubulin subunit beta 0.0091 0.0113 0.0104
Loa Loa (eye worm) melatonin receptor type 1A 0.0248 0.055 0.0686
Echinococcus multilocularis neuropeptide FF receptor 2 0.0469 0.1163 0.1163
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0158 0.0299 0.0299
Leishmania major beta tubulin 0.0091 0.0113 0.0421
Leishmania major beta tubulin 0.0091 0.0113 0.0421
Echinococcus granulosus 7TM GPCR rhodopsin 0.0248 0.055 0.055
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0248 0.055 0.0543
Brugia malayi nuclear receptor NHR-88 0.0082 0.0087 0.0075
Schistosoma mansoni RAR-like nuclear receptor 0.0082 0.0087 0.0078
Toxoplasma gondii transporter, cation channel family protein 0.0158 0.0299 0.0501
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0082 0.0087 0.0087
Onchocerca volvulus 0.0116 0.0181 0.1749
Echinococcus multilocularis ring and YY1 binding protein 0.0074 0.0064 0.0064
Loa Loa (eye worm) hypothetical protein 0.0248 0.055 0.0686
Schistosoma mansoni amine GPCR 0.0248 0.055 0.0543
Loa Loa (eye worm) hypothetical protein 0.0082 0.0087 0.0075
Entamoeba histolytica heat shock protein 90, putative 0.0139 0.0246 1
Loa Loa (eye worm) hypothetical protein 0.0248 0.055 0.0686
Plasmodium vivax endoplasmin, putative 0.0139 0.0246 0.4974
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0248 0.055 0.0686
Loa Loa (eye worm) tubulin beta-2A chain 0.0091 0.0113 0.0109
Trypanosoma brucei hypothetical protein 0.0114 0.0177 0.1968
Loa Loa (eye worm) endoprotease bli-4 0.086 0.2247 0.2927
Leishmania major hypothetical protein, conserved 0.0074 0.0064 0.0044
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.0367 0.088 0.088
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0248 0.055 0.055
Loa Loa (eye worm) hypothetical protein 0.0248 0.055 0.0686
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0114 0.0177 0.1968
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0248 0.055 0.055
Schistosoma mansoni growth hormone secretagogue receptor 0.0248 0.055 0.0543
Echinococcus granulosus glutamate NMDA receptor subunit 0.0274 0.0622 0.0622
Brugia malayi Melatonin receptor type 1A 0.0248 0.055 0.0686
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0224 0.0481 0.2999
Echinococcus multilocularis beta tubulin 0.0091 0.0113 0.0113
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0082 0.0087 0.0075
Schistosoma mansoni hypothetical protein 0.0248 0.055 0.0543
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0082 0.0087 0.0075
Loa Loa (eye worm) PAN domain-containing protein 0.0116 0.0181 0.0199
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0082 0.0087 0.0087
Echinococcus granulosus rhodopsin orphan GPCR 0.0248 0.055 0.055
Loa Loa (eye worm) tubulin beta-4 chain 0.0091 0.0113 0.0109
Loa Loa (eye worm) heat shock protein 90 0.0139 0.0246 0.0284
Brugia malayi PAN domain containing protein 0.0116 0.0181 0.0199
Brugia malayi PAN domain containing protein 0.0116 0.0181 0.0199
Toxoplasma gondii heat shock protein 90, putative 0.0139 0.0246 0.039
Trichomonas vaginalis glucosylceramidase, putative 0.0181 0.0363 0.2036
Leishmania major heat shock protein 83-1 0.0139 0.0246 0.1454
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0082 0.0087 0.0078
Loa Loa (eye worm) hypothetical protein 0.0248 0.055 0.0686
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0262 0.0587 0.0735
Plasmodium falciparum SWIB/MDM2 domain-containing protein 0.0207 0.0435 1
Trichomonas vaginalis glucosylceramidase, putative 0.0172 0.0337 0.1827
Onchocerca volvulus Adenylate cyclase type 2 homolog 0.0061 0.0031 0.008
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0114 0.0177 0.1968
Trichomonas vaginalis AGC family protein kinase 0.0109 0.0163 0.0412
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0248 0.055 0.0686
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0114 0.0177 0.1968
Loa Loa (eye worm) PAN domain-containing protein 0.0116 0.0181 0.0199
Loa Loa (eye worm) hypothetical protein 0.0248 0.055 0.0686
Leishmania major beta tubulin 0.0091 0.0113 0.0421
Plasmodium falciparum tubulin beta chain 0.0091 0.0113 0.1439
Onchocerca volvulus 0.0248 0.055 0.5827
Schistosoma mansoni opsin-like receptor 0.0248 0.055 0.0543
Trypanosoma brucei heat shock protein 90, putative 0.0139 0.0246 0.2737
Onchocerca volvulus 0.0248 0.055 0.5827
Loa Loa (eye worm) hypothetical protein 0.0248 0.055 0.0686
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0248 0.055 0.5827
Echinococcus multilocularis serotonin receptor 0.0248 0.055 0.055
Echinococcus granulosus MAP kinase activated protein kinase 2 0.0178 0.0353 0.0353
Schistosoma mansoni thyroid hormone receptor 0.0082 0.0087 0.0078
Schistosoma mansoni tubulin subunit beta 0.0091 0.0113 0.0104
Brugia malayi Nuclear hormone receptor-like 1 0.0082 0.0087 0.0075
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0248 0.055 0.0686
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0082 0.0087 0.0087
Trichomonas vaginalis glucosylceramidase, putative 0.0172 0.0337 0.1827
Brugia malayi Protein kinase domain containing protein 0.0072 0.0059 0.0037
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0114 0.0177 0.1968
Trypanosoma brucei C-8 sterol isomerase, putative 0.0373 0.0897 1
Onchocerca volvulus 0.0074 0.0066 0.0475
Loa Loa (eye worm) bone morphogenic protein 6 0.0126 0.0211 0.0238
Loa Loa (eye worm) latrophilin receptor protein 2 0.0711 0.1833 0.238
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0082 0.0087 0.0075
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0082 0.0087 0.0075
Echinococcus multilocularis rhodopsin orphan GPCR 0.0248 0.055 0.055
Schistosoma mansoni biogenic amine (5HT) receptor 0.0248 0.055 0.0543
Schistosoma mansoni biogenic amine receptor 0.0248 0.055 0.0543
Brugia malayi PAN domain containing protein 0.0116 0.0181 0.0199
Leishmania major heat shock protein 83-1 0.0139 0.0246 0.1454
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0248 0.055 0.055
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0126 0.0209 0.1171
Echinococcus granulosus G protein coupled receptor 139 0.0248 0.055 0.055
Trichomonas vaginalis conserved hypothetical protein 0.0183 0.0369 0.2084
Trypanosoma brucei heat shock protein, putative 0.0139 0.0246 0.2737
Trichomonas vaginalis AGC family protein kinase 0.0109 0.0163 0.0412
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0248 0.055 0.055
Echinococcus multilocularis neuropeptide receptor A26 0.0763 0.1978 0.1978
Trypanosoma brucei heat shock protein, putative 0.0139 0.0246 0.2737
Onchocerca volvulus 0.0072 0.0059 0.0392
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0711 0.1833 0.1833
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0248 0.055 0.0543
Loa Loa (eye worm) hypothetical protein 0.0711 0.1833 0.238
Echinococcus multilocularis neuropeptide receptor 0.0248 0.055 0.055
Toxoplasma gondii 1,3(4)-beta-glucanase 0.0116 0.0181 0.0256
Trypanosoma brucei hypothetical protein, conserved 0.0074 0.0064 0.0713
Brugia malayi hypothetical protein 0.0074 0.0066 0.0047
Echinococcus multilocularis neuropeptide Y receptor 0.0248 0.055 0.055
Loa Loa (eye worm) hypothetical protein 0.0248 0.055 0.0686
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0373 0.0897 0.1144
Trichomonas vaginalis glucosylceramidase, putative 0.0262 0.0587 0.3865
Toxoplasma gondii microneme protein MIC17A 0.0116 0.0181 0.0256
Loa Loa (eye worm) hypothetical protein 0.0248 0.055 0.0686
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0082 0.0087 0.0078
Echinococcus granulosus heat shock protein 90 0.0126 0.0209 0.0209
Schistosoma mansoni neuropeptide F-like receptor 0.0248 0.055 0.0543
Schistosoma mansoni hypothetical protein 0.0367 0.088 0.0873
Trypanosoma brucei calpain, putative 0.0114 0.0177 0.1968
Leishmania major heat shock protein 83-1 0.0139 0.0246 0.1454
Echinococcus multilocularis Tubulin beta 2C chain 0.0091 0.0113 0.0113
Loa Loa (eye worm) pigment dispersing factor receptor c 0.2136 0.5792 0.7608
Brugia malayi photoreceptor-specific nuclear receptor 0.0082 0.0087 0.0075
Loa Loa (eye worm) hypothetical protein 0.0116 0.0181 0.0199
Echinococcus multilocularis rhodopsin orphan GPCR 0.0248 0.055 0.055
Echinococcus granulosus g-protein coupled receptor 0.0248 0.055 0.055
Echinococcus granulosus serotonin receptor 0.0248 0.055 0.055
Toxoplasma gondii SWIB/MDM2 domain-containing protein 0.0207 0.0435 0.0784
Loa Loa (eye worm) hypothetical protein 0.086 0.2247 0.2927
Treponema pallidum heat shock protein 90 0.0126 0.0209 1
Leishmania major beta tubulin 0.0091 0.0113 0.0421
Echinococcus granulosus tumor protein p63 0.0334 0.0788 0.0788
Giardia lamblia High cysteine membrane protein Group 2 0.0309 0.0719 1
Loa Loa (eye worm) neuropeptide F receptor 0.0248 0.055 0.0686
Echinococcus multilocularis adenylate cyclase type IX 0.0086 0.01 0.01
Onchocerca volvulus 0.0116 0.0181 0.1749
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0248 0.055 0.0543
Echinococcus granulosus alpha 1A adrenergic receptor 0.0248 0.055 0.055
Loa Loa (eye worm) hypothetical protein 0.0082 0.0087 0.0075
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0248 0.055 0.055
Loa Loa (eye worm) TK/EGFR protein kinase 0.0135 0.0234 0.0269
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0384 0.0927 0.0921
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0082 0.0087 0.0075
Leishmania major beta tubulin 0.0091 0.0113 0.0421
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0114 0.0177 0.1968
Echinococcus multilocularis neuropeptide s receptor 0.0763 0.1978 0.1978
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0114 0.0177 0.1968
Trypanosoma cruzi heat shock protein 85, putative 0.0126 0.0209 0.2331
Toxoplasma gondii PAN domain-containing protein 0.0116 0.0181 0.0256
Loa Loa (eye worm) hypothetical protein 0.0248 0.055 0.0686
Echinococcus multilocularis proprotein convertase subtilisin:kexin type 5 0.0533 0.134 0.134
Echinococcus granulosus rhodopsin orphan GPCR 0.0248 0.055 0.055
Echinococcus multilocularis sodium channel protein 0.0535 0.1345 0.1345
Echinococcus granulosus L aminoadipate semialdehyde 0.01 0.0139 0.0139
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0082 0.0087 0.0075
Echinococcus multilocularis FTZ F1 alpha 0.0082 0.0087 0.0087
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0158 0.0299 0.0291
Echinococcus multilocularis g protein coupled receptor 0.0248 0.055 0.055
Echinococcus multilocularis somatostatin receptor 0.0248 0.055 0.055
Trypanosoma cruzi heat shock protein 90, putative 0.0113 0.0173 0.1919
Echinococcus granulosus proprotein convertase subtilisin:kexin type 5 0.0533 0.134 0.134
Onchocerca volvulus 0.0207 0.0435 0.4554
Brugia malayi PAN domain containing protein 0.0116 0.0181 0.0199
Loa Loa (eye worm) hypothetical protein 0.0072 0.0059 0.0037
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0248 0.055 0.0543
Schistosoma mansoni amine GPCR 0.0248 0.055 0.0543
Trypanosoma brucei beta tubulin 0.0091 0.0113 0.1254
Leishmania major heat shock protein 83-1 0.0139 0.0246 0.1454
Echinococcus granulosus beta tubulin 0.0091 0.0113 0.0113
Trichomonas vaginalis glucosylceramidase, putative 0.0172 0.0337 0.1827
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0533 0.134 1
Echinococcus granulosus Tubulin beta 2C chain 0.0091 0.0113 0.0113
Brugia malayi heat shock protein 90 0.0139 0.0246 0.0284
Brugia malayi steroid hormone receptor 0.0082 0.0087 0.0075
Onchocerca volvulus 0.0248 0.055 0.5827
Echinococcus multilocularis neuropeptides capa receptor 0.0248 0.055 0.055
Trypanosoma brucei variant surface glycoprotein (VSG), putative 0.0114 0.0177 0.1968
Echinococcus multilocularis tissue type plasminogen activator 0.0072 0.0059 0.0059
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0082 0.0087 0.0075
Plasmodium vivax SWIB/MDM2 domain-containing protein, putative 0.0207 0.0435 1
Trypanosoma cruzi hypothetical protein, conserved 0.0072 0.0059 0.065
Schistosoma mansoni serine-type protease inhibitor 0.3645 0.9981 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0082 0.0087 0.0087
Loa Loa (eye worm) hypothetical protein 0.011 0.0164 0.0176
Loa Loa (eye worm) calcium channel 0.0158 0.0299 0.0355
Trichomonas vaginalis conserved hypothetical protein 0.0183 0.0369 0.2084
Leishmania major hypothetical protein, conserved 0.0074 0.0064 0.0044
Schistosoma mansoni zinc finger protein 0.0074 0.0064 0.0056
Echinococcus granulosus heat shock protein 90 0.0139 0.0246 0.0246
Leishmania major hypothetical protein, conserved 0.0074 0.0064 0.0044
Trichomonas vaginalis heat shock protein, putative 0.0126 0.0209 0.0786
Echinococcus granulosus GPCR family 2 0.0711 0.1833 0.1833
Echinococcus granulosus biogenic amine 5HT receptor 0.0248 0.055 0.055
Loa Loa (eye worm) hypothetical protein 0.0469 0.1163 0.1496
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0248 0.055 0.055
Trichomonas vaginalis heat shock protein, putative 0.0126 0.0209 0.0786
Leishmania major hypothetical protein, conserved 0.0074 0.0064 0.0044
Loa Loa (eye worm) apoptosis regulator protein 0.0367 0.088 0.1121
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0248 0.055 0.055
Brugia malayi PAN domain containing protein 0.0116 0.0181 0.0199
Loa Loa (eye worm) SWIB/MDM2 domain-containing protein 0.0207 0.0435 0.0534
Schistosoma mansoni hypothetical protein 0.0248 0.055 0.0543
Echinococcus granulosus somatostatin receptor 0.0248 0.055 0.055
Echinococcus granulosus g protein coupled receptor 0.0248 0.055 0.055
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0248 0.055 0.055
Echinococcus granulosus neuropeptides capa receptor 0.0248 0.055 0.055
Schistosoma mansoni hypothetical protein 0.0367 0.088 0.0873
Trypanosoma brucei hypothetical protein, conserved 0.0074 0.0064 0.0713
Echinococcus multilocularis neuroendocrine convertase 2 0.055 0.1388 0.1388
Trichomonas vaginalis AGC family protein kinase 0.0109 0.0163 0.0412
Trichomonas vaginalis heat shock protein, putative 0.0139 0.0246 0.1083
Echinococcus multilocularis g-protein coupled receptor 0.0248 0.055 0.055
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0545 0.1373 0.1373
Schistosoma mansoni fusion 0.0074 0.0064 0.0056
Onchocerca volvulus 0.0248 0.055 0.5827
Brugia malayi beta-tubulin, identical 0.0091 0.0113 0.0109

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 6.5131 uM PUBCHEM_BIOASSAY: Nrf2 qHTS screen for inhibitors. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493153, AID493163, AID504648] ChEMBL. No reference
Potency (functional) = 15.8489 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Bacillus subtilis Sfp phosphopantetheinyl transferase (PPTase). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 21.3313 uM PUBCHEM_BIOASSAY: qHTS profiling assay for firefly luciferase inhibitor/activator using purified enzyme and Km concentrations of substrates (counterscreen for miR-21 project). (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2288, AID2289, AID2598, AID411] ChEMBL. No reference
Potency (functional) = 28.1838 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1). (Class of assay: confirmatory) [Related pubchem assays: 1030 (qHTS Validation Assay for Inhibitors of aldehyde dehydrogenase 1 (ALDH1A1))] ChEMBL. No reference
Potency (functional) = 31.6228 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Human Jumonji Domain Containing 2E (JMJD2E). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 39.8107 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase). (Class of assay: confirmatory) [Related pubchem assays: 2429 (Confirmation qHTS Assay for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase)), 2407 (Probe Development Summary for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase)), 2427 (Thermal Shift Assay for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase))] ChEMBL. No reference
Potency (functional) 39.8107 uM PubChem BioAssay. qHTS Assay for Activators of ClpP. (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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