Detailed information for compound 1462412

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 413.402 | Formula: C22H20N3NaO4
  • H donors: 2 H acceptors: 4 LogP: 1.1 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC[C@@]1([O-])C(=O)OCc2c1cc1c3nc4ccc(cc4c(c3Cn1c2=O)CC)N.[Na+]
  • InChi: 1S/C22H20N3O4.Na/c1-3-12-13-7-11(23)5-6-17(13)24-19-14(12)9-25-18(19)8-16-15(20(25)26)10-29-21(27)22(16,28)4-2;/h5-8H,3-4,9-10,23H2,1-2H3;/q-1;+1/t22-;/m0./s1
  • InChiKey: JYGBYZSLQGKKGB-FTBISJDPSA-N  


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Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Plasmodium vivax vivapain-2 0.0022 0.0219 0.0282
Entamoeba histolytica hypothetical protein 0.0085 0.1295 0.2032
Trichomonas vaginalis esterase, putative 0.0035 0.0442 0.0711
Brugia malayi Matrixin family protein 0.0021 0.021 0.0174
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0022 0.0219 0.0352
Loa Loa (eye worm) matrixin family protein 0.0052 0.0725 0.0796
Giardia lamblia Histone deacetylase 0.0375 0.622 1
Brugia malayi Cathepsin L-like precursor 0.0022 0.0219 0.0183
Toxoplasma gondii histone deacetylase HDAC2 0.0375 0.622 0.9655
Loa Loa (eye worm) hypothetical protein 0.0182 0.2947 0.3238
Brugia malayi Matrixin family protein 0.0021 0.021 0.0174
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0744 0.1196
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0022 0.0219 0.0282
Leishmania major histone deacetylase, putative 0.0375 0.622 0.9659
Brugia malayi Histone deacetylase family protein 0.0388 0.6436 0.6489
Giardia lamblia Glycogen phosphorylase 0.0119 0.1867 0.2798
Brugia malayi carbohydrate phosphorylase 0.0119 0.1867 0.1855
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0022 0.0219 0.0352
Echinococcus granulosus histone deacetylase 6 0.0388 0.6436 0.6432
Loa Loa (eye worm) hypothetical protein 0.0029 0.034 0.0374
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0029 0.034 0.0303
Brugia malayi Cathepsin L-like precursor 0.0022 0.0219 0.0183
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0022 0.0219 0.0282
Trichomonas vaginalis glycogen phosphorylase, putative 0.0119 0.1867 0.3002
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0375 0.622 1
Brugia malayi WGR domain containing protein 0.0085 0.1295 0.1274
Leishmania major cysteine peptidase A (CPA) 0.0022 0.0219 0.0205
Trichomonas vaginalis glycogen phosphorylase, putative 0.0119 0.1867 0.3002
Loa Loa (eye worm) poly(ADP-ribose) polymerase 0.0085 0.1295 0.1423
Loa Loa (eye worm) hypothetical protein 0.0021 0.021 0.023
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0022 0.0219 0.0352
Schistosoma mansoni hypothetical protein 0.0053 0.0744 0.0708
Echinococcus multilocularis u4:u6.u5 tri snrnp associated protein 2 0.0019 0.0176 0.0177
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0022 0.0219 0.0352
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0019 0.0176 0.0284
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0285 0.4682 0.7528
Trichomonas vaginalis histone deacetylase, putative 0.0375 0.622 1
Echinococcus granulosus Sterile alpha motif SAM 0.0053 0.0744 0.0709
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0035 0.0442 0.041
Echinococcus granulosus beta LACTamase domain containing family member 0.0035 0.0442 0.0406
Mycobacterium tuberculosis Probable hydrolase 0.0035 0.0442 0.042
Brugia malayi Cathepsin L-like precursor 0.0015 0.0096 0.0058
Trichomonas vaginalis conserved hypothetical protein 0.0085 0.1295 0.2081
Schistosoma mansoni cathepsin F (C01 family) 0.0022 0.0219 0.0181
Echinococcus granulosus matrix metallopeptidase 7 M10 family 0.0078 0.1167 0.1135
Entamoeba histolytica hypothetical protein 0.0085 0.1295 0.2032
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0442 0.0711
Mycobacterium leprae Probable lipase LipE 0.0035 0.0442 0.042
Schistosoma mansoni glycogen phosphorylase 0.0119 0.1867 0.1836
Brugia malayi Papain family cysteine protease containing protein 0.0022 0.0219 0.0183
Leishmania major cathepsin L-like protease 0.0022 0.0219 0.0205
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0203 0.329 0.3615
Echinococcus multilocularis stromal interaction molecule 1 0.0053 0.0744 0.0745
Brugia malayi Cathepsin L-like precursor 0.0022 0.0219 0.0183
Trypanosoma cruzi Ring finger domain/Zn-finger in ubiquitin-hydrolases and other protein, putative 0.0019 0.0176 0.0216
Echinococcus multilocularis SAM domain containing protein 0.0053 0.0744 0.0745
Schistosoma mansoni sarm1 0.0053 0.0744 0.0708
Trypanosoma brucei Peptide deformylase 2 0.0092 0.1409 0.2142
Trypanosoma cruzi cysteine peptidase, putative 0.0022 0.0219 0.0282
Schistosoma mansoni ubiquitin-specific peptidase 44 (C19 family) 0.0019 0.0176 0.0139
Schistosoma mansoni poly [ADP-ribose] polymerase 0.0085 0.1295 0.1261
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 22 0.0019 0.0176 0.0177
Loa Loa (eye worm) hypothetical protein 0.0035 0.0442 0.0486
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0025 0.0277 0.0374
Loa Loa (eye worm) hypothetical protein 0.0035 0.0442 0.0486
Plasmodium falciparum peptide deformylase 0.0241 0.3941 0.61
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0442 0.0711
Onchocerca volvulus 0.0035 0.0442 0.0391
Plasmodium falciparum flap endonuclease 1 0.0025 0.0277 0.0374
Schistosoma mansoni brca1-associated protein (brap2) 0.0019 0.0176 0.0139
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0019 0.0176 0.0224
Brugia malayi Matrixin family protein 0.0021 0.021 0.0174
Entamoeba histolytica glycogen phosphorylase, putative 0.0119 0.1867 0.2959
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0224 0.3652 0.921
Trypanosoma brucei Polypeptide deformylase 1 0.0092 0.1409 0.2142
Trichomonas vaginalis c2h2 zinc finger protein, putative 0.0053 0.0744 0.1196
Echinococcus multilocularis BRCA1 associated protein 0.0019 0.0176 0.0177
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0744 0.1196
Brugia malayi Histone deacetylase 1 0.0375 0.622 0.6269
Echinococcus granulosus histone deacetylase 1 0.0375 0.622 0.6214
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0035 0.0442 0.042
Brugia malayi Matrix metalloprotease, N-terminal domain containing protein 0.0026 0.0289 0.0254
Trypanosoma brucei histone deacetylase, putative 0.0388 0.6436 1
Giardia lamblia Fructose-bisphosphate aldolase 0.0285 0.4682 0.7456
Trichomonas vaginalis conserved hypothetical protein 0.0085 0.1295 0.2081
Leishmania major cathepsin L-like protease 0.0022 0.0219 0.0205
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0022 0.0219 0.0282
Loa Loa (eye worm) cysteine protease 0.0022 0.0219 0.024
Trypanosoma cruzi cysteine peptidase, putative 0.0022 0.0219 0.0282
Trichomonas vaginalis histone deacetylase, putative 0.0375 0.622 1
Echinococcus multilocularis histone deacetylase 1 0.0375 0.622 0.6229
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0025 0.0277 0.0161
Brugia malayi Cytochrome P450 family protein 0.0014 0.0088 0.0051
Echinococcus granulosus glycogen phosphorylase 0.0119 0.1867 0.1839
Schistosoma mansoni hypothetical protein 0.003 0.0362 0.0325
Plasmodium vivax hypothetical protein, conserved 0.0035 0.0442 0.0631
Leishmania major hypothetical protein, conserved 0.0035 0.0442 0.0557
Schistosoma mansoni histone deacetylase 4 5 0.0388 0.6436 0.6423
Loa Loa (eye worm) hypothetical protein 0.0035 0.0442 0.0486
Leishmania major histone deacetylase, putative 0.0388 0.6436 1
Leishmania major cathepsin L-like protease 0.0022 0.0219 0.0205
Onchocerca volvulus 0.0022 0.0219 0.0139
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0035 0.0442 0.042
Entamoeba histolytica glycogen phosphorylase, putative 0.0051 0.072 0.1103
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0285 0.4682 0.7528
Trichomonas vaginalis histone deacetylase, putative 0.0375 0.622 1
Schistosoma mansoni matrix metallopeptidase-7 (M10 family) 0.0021 0.021 0.0172
Entamoeba histolytica hypothetical protein 0.0085 0.1295 0.2032
Echinococcus granulosus sterile alpha and tir motif containing protein 0.0053 0.0744 0.0709
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0285 0.4682 0.7513
Plasmodium vivax flap endonuclease 1, putative 0.0025 0.0277 0.0374
Leishmania major cathepsin L-like protease 0.0022 0.0219 0.0205
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0019 0.0176 0.0139
Wolbachia endosymbiont of Brugia malayi peptide deformylase 0.0241 0.3941 0.5
Onchocerca volvulus 0.0232 0.378 0.4161
Trypanosoma cruzi polypeptide deformylase-like protein, putative 0.0092 0.1409 0.2142
Echinococcus multilocularis glycogen phosphorylase 0.0119 0.1867 0.187
Trypanosoma cruzi cysteine peptidase, putative 0.0022 0.0219 0.0282
Mycobacterium tuberculosis Probable polypeptide deformylase Def (PDF) (formylmethionine deformylase) 0.0241 0.3941 1
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0375 0.622 1
Echinococcus granulosus BRCA1 associated protein 0.0019 0.0176 0.0139
Loa Loa (eye worm) histone deacetylase 3 0.0375 0.622 0.6834
Echinococcus multilocularis sterile alpha and tir motif containing protein 0.0053 0.0744 0.0745
Echinococcus granulosus peptidase s8 s53 subtilisin kexin sedolisin 0.0099 0.1524 0.1493
Brugia malayi histone deacetylase 11 0.0367 0.6076 0.6123
Mycobacterium ulcerans glycogen phosphorylase GlgP 0.0051 0.072 0.164
Brugia malayi Cathepsin L-like precursor 0.0022 0.0219 0.0183
Loa Loa (eye worm) hypothetical protein 0.0053 0.0744 0.0817
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0022 0.0219 0.0352
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0022 0.0219 0.0352
Trypanosoma brucei cytochrome P450, putative 0.0014 0.0088 0.0078
Loa Loa (eye worm) hypothetical protein 0.0204 0.3307 0.3634
Entamoeba histolytica zinc finger protein, putative 0.0085 0.1295 0.2032
Echinococcus granulosus poly adp ribose polymerase 2 0.0085 0.1295 0.1263
Entamoeba histolytica Flap nuclease, putative 0.0025 0.0277 0.0387
Echinococcus granulosus SAM domain containing protein 0.0053 0.0744 0.0709
Trypanosoma cruzi cysteine peptidase, putative 0.0022 0.0219 0.0282
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0019 0.0176 0.0284
Schistosoma mansoni glycogen phosphorylase 0.0051 0.072 0.0685
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 5 0.0019 0.0176 0.0177
Trypanosoma brucei Ring finger domain/Zn-finger in ubiquitin-hydrolases and other protein, putative 0.0019 0.0176 0.0216
Trypanosoma brucei histone deacetylase 1 0.0375 0.622 0.9662
Echinococcus multilocularis poly (ADP ribose) polymerase 1 0.0085 0.1295 0.1297
Trypanosoma cruzi poly(ADP-ribose) polymerase, putative 0.0085 0.1295 0.1964
Entamoeba histolytica cysteine proteinase, putative 0.0022 0.0219 0.0292
Brugia malayi Tnks protein 0.0592 0.9899 1
Trypanosoma brucei histone deacetylase 2 0.0184 0.2976 0.4591
Echinococcus granulosus histone deacetylase 3 0.0375 0.622 0.6214
Loa Loa (eye worm) matrixin family protein 0.0047 0.0652 0.0717
Loa Loa (eye worm) beta-lactamase 0.0035 0.0442 0.0486
Echinococcus granulosus cathepsin L cysteine proteinase 0.0022 0.0219 0.0181
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase, putative 0.0019 0.0176 0.0216
Loa Loa (eye worm) ctsf protein 0.0022 0.0219 0.024
Loa Loa (eye worm) tnks protein 0.0545 0.9101 1
Brugia malayi Cathepsin L-like precursor 0.0022 0.0219 0.0183
Plasmodium vivax hypothetical protein, conserved 0.0019 0.0176 0.0216
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0022 0.0219 0.0219
Trichomonas vaginalis ankyrin 2,3/unc44, putative 0.0011 0.0038 0.0061
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.0085 0.1295 0.1786
Brugia malayi beta-lactamase family protein 0.0035 0.0442 0.041
Mycobacterium tuberculosis Probable lipase LipD 0.0035 0.0442 0.042
Echinococcus multilocularis histone deacetylase 0.0388 0.6436 0.6446
Echinococcus granulosus cathepsin l1 0.0015 0.0096 0.0058
Trypanosoma cruzi histone deacetylase 1, putative 0.0375 0.622 0.9662
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0035 0.0442 0.0486
Loa Loa (eye worm) hypothetical protein 0.0223 0.3637 0.3996
Entamoeba histolytica hypothetical protein 0.0085 0.1295 0.2032
Leishmania major polypeptide deformylase-like protein, putative 0.0092 0.1409 0.208
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0029 0.034 0.0341
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0019 0.0176 0.0216
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0025 0.0277 0.0298
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0022 0.0219 0.0352
Echinococcus granulosus liprin alpha 2 0.0053 0.0744 0.0709
Brugia malayi Liprin-alpha 2 0.0053 0.0744 0.0716
Echinococcus multilocularis matrix metallopeptidase 7 (M10 family) 0.0078 0.1167 0.1169
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0019 0.0176 0.0216
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0015 0.0096 0.0154
Mycobacterium tuberculosis Conserved protein 0.0035 0.0442 0.042
Onchocerca volvulus 0.003 0.0362 0.03
Echinococcus multilocularis histone deacetylase 7 0.0388 0.6436 0.6446
Schistosoma mansoni histone deacetylase 1 2 3 0.0184 0.2976 0.2949
Schistosoma mansoni hypothetical protein 0.0053 0.0744 0.0708
Entamoeba histolytica glycogen phosphorylase, putative 0.0119 0.1867 0.2959
Echinococcus multilocularis poly (adp ribose) polymerase 2 0.0085 0.1295 0.1297
Onchocerca volvulus Glycogen phosphorylase homolog 0.0119 0.1867 0.2001
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0025 0.0277 0.0374
Echinococcus granulosus glycogen phosphorylase 0.0119 0.1867 0.1839
Loa Loa (eye worm) hypothetical protein 0.0085 0.1295 0.1423
Onchocerca volvulus 0.0022 0.0219 0.0139
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0442 0.0631
Mycobacterium ulcerans hydrolase 0.0026 0.0289 0.0521
Trypanosoma cruzi cytochrome P450, putative 0.0014 0.0088 0.0078
Entamoeba histolytica glycogenphosphorylase, putative 0.0051 0.072 0.1103
Trichomonas vaginalis conserved hypothetical protein 0.0085 0.1295 0.2081
Trypanosoma cruzi cruzipain precursor, putative 0.0022 0.0219 0.0282
Trypanosoma brucei Zn-finger in ubiquitin-hydrolases and other protein, putative 0.0019 0.0176 0.0216
Giardia lamblia Flap structure-specific endonuclease 0.0025 0.0277 0.0167
Loa Loa (eye worm) hypothetical protein 0.0035 0.0442 0.0486
Brugia malayi Histone deacetylase family protein 0.0388 0.6436 0.6489
Mycobacterium ulcerans hypothetical protein 0.0035 0.0442 0.0919
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0019 0.0176 0.0194
Schistosoma mansoni family C19 non-peptidase homologue (C19 family) 0.0019 0.0176 0.0139
Loa Loa (eye worm) hypothetical protein 0.0053 0.0744 0.0817
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0322 0.0286
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0019 0.0176 0.014
Treponema pallidum fructose-bisphosphate aldolase 0.0285 0.4682 1
Loa Loa (eye worm) hypothetical protein 0.0035 0.0442 0.0486
Brugia malayi Matrixin family protein 0.0021 0.021 0.0174
Trypanosoma cruzi Ring finger domain/Zn-finger in ubiquitin-hydrolases and other protein, putative 0.0019 0.0176 0.0216
Plasmodium vivax histone deacetylase, putative 0.0367 0.6076 0.9437
Echinococcus granulosus tankyrase 0.0597 0.9986 1
Schistosoma mansoni flap endonuclease-1 0.0023 0.0236 0.0199
Brugia malayi beta-lactamase 0.0035 0.0442 0.041
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0022 0.0219 0.0282
Trichomonas vaginalis set domain proteins, putative 0.0231 0.3766 0.6054
Trichomonas vaginalis conserved hypothetical protein 0.0085 0.1295 0.2081
Echinococcus granulosus histone lysine methyltransferase setb 0.0029 0.034 0.0304
Echinococcus granulosus cathepsin l1 0.0022 0.0219 0.0181
Plasmodium falciparum tyrosine kinase-like protein 0.0053 0.0744 0.1103
Trichomonas vaginalis histone deacetylase, putative 0.0375 0.622 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0022 0.0219 0.0352
Loa Loa (eye worm) matrix metalloproteinase 0.0021 0.021 0.023
Leishmania major hypothetical protein, conserved 0.0019 0.0176 0.0139
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase 13, putative 0.0019 0.0176 0.0216
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0285 0.4682 0.7528
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0022 0.0219 0.0352
Toxoplasma gondii ABC1 family protein 0.0035 0.0442 0.0425
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0019 0.0176 0.0284
Brugia malayi Flap endonuclease-1 0.0025 0.0277 0.0243
Echinococcus multilocularis poly (ADP ribose) polymerase 0.0085 0.1295 0.1297
Loa Loa (eye worm) hypothetical protein 0.0022 0.0219 0.024
Mycobacterium tuberculosis Conserved protein 0.0035 0.0442 0.042
Echinococcus multilocularis cathepsin L cysteine protease 0.0022 0.0219 0.0219
Brugia malayi histone deacetylase 1 (HD1) 0.0375 0.622 0.6269
Echinococcus multilocularis cathepsin L 0.0011 0.0038 0.0038
Echinococcus multilocularis liprin beta 1 0.0053 0.0744 0.0745
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0022 0.0219 0.0282
Onchocerca volvulus Matrilysin homolog 0.0047 0.0652 0.0629
Loa Loa (eye worm) hypothetical protein 0.0375 0.622 0.6834
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0442 0.0711
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0019 0.0176 0.014
Echinococcus multilocularis cysteine protease 0.0022 0.0219 0.0219
Trichomonas vaginalis conserved hypothetical protein 0.0085 0.1295 0.2081
Echinococcus multilocularis liprin alpha 2 0.0053 0.0744 0.0745
Plasmodium falciparum histone deacetylase 1 0.0375 0.622 0.9662
Loa Loa (eye worm) hypothetical protein 0.0053 0.0744 0.0817
Onchocerca volvulus 0.0022 0.0219 0.0139
Onchocerca volvulus Matrilysin homolog 0.0021 0.021 0.0129
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0011 0.0038 0.0061
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0022 0.0219 0.0352
Mycobacterium tuberculosis Probable lipase LipE 0.0035 0.0442 0.042
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0442 0.0631
Mycobacterium tuberculosis Probable glycogen phosphorylase GlgP 0.0051 0.072 0.1181
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0022 0.0219 0.0282
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0285 0.4682 0.7513
Trypanosoma cruzi histone deacetylase, putative 0.0388 0.6436 1
Plasmodium vivax SET domain protein, putative 0.0029 0.034 0.0472
Onchocerca volvulus 0.0022 0.0219 0.0139
Brugia malayi coiled-coil like protein 1 0.0053 0.0744 0.0716
Brugia malayi cathepsin L-like precursor 0.0015 0.0096 0.0058
Leishmania major histone deacetylase, putative 0.0375 0.622 0.9659
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0375 0.622 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0022 0.0219 0.0352
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0022 0.0219 0.0352
Echinococcus multilocularis glycogen phosphorylase 0.0119 0.1867 0.187
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0744 0.1196
Mycobacterium tuberculosis Probable esterase LipL 0.0035 0.0442 0.042
Leishmania major histone deacetylase, putative 0.0388 0.6436 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0022 0.0219 0.0282
Echinococcus granulosus Glycosyl transferase family 35 0.0119 0.1867 0.1839
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0139 0.2209 0.5257
Brugia malayi Cytochrome P450 family protein 0.0014 0.0088 0.0051
Entamoeba histolytica histone deacetylase, putative 0.0375 0.622 1
Echinococcus multilocularis histone deacetylase 6 0.0388 0.6436 0.6446
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.001 0.0024 0.0038
Loa Loa (eye worm) hypothetical protein 0.0451 0.7515 0.8257
Brugia malayi Matrixin family protein 0.0052 0.0725 0.0696
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0022 0.0219 0.0352
Brugia malayi Hemopexin family protein 0.003 0.0362 0.0328
Mycobacterium tuberculosis Conserved protein 0.0035 0.0442 0.042
Plasmodium vivax histone deacetylase 2, putative 0.0388 0.6436 1
Brugia malayi Subtilase family protein 0.0264 0.4326 0.4348
Brugia malayi Pre-SET motif family protein 0.0029 0.034 0.0306
Trypanosoma cruzi polypeptide deformylase-like protein, putative 0.0092 0.1409 0.2142
Echinococcus multilocularis nuclear receptor co repressor related (ncor) 0.0289 0.4758 0.4765
Schistosoma mansoni lar interacting protein (lip)-related protein 0.0053 0.0744 0.0708
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0022 0.0219 0.0352
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0053 0.0744 0.0906
Trypanosoma cruzi poly(ADP-ribose) polymerase, putative 0.0085 0.1295 0.1964
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0022 0.0219 0.0352
Onchocerca volvulus 0.0053 0.0744 0.0732
Schistosoma mansoni cathepsin F (C01 family) 0.0022 0.0219 0.0181
Trypanosoma cruzi histone deacetylase, putative 0.0388 0.6436 1
Trypanosoma cruzi histone deacetylase, putative 0.0184 0.2976 0.4591
Mycobacterium leprae PROBABLE POLYPEPTIDE DEFORMYLASE DEF (PDF) (FORMYLMETHIONINE DEFORMYLASE) 0.0241 0.3941 1
Echinococcus multilocularis Glycosyl transferase, family 35 0.0119 0.1867 0.187
Brugia malayi BRCA1-associated protein 2 containing protein 0.0019 0.0176 0.014
Loa Loa (eye worm) hypothetical protein 0.0021 0.021 0.023
Echinococcus granulosus poly ADP ribose polymerase 1 0.0085 0.1295 0.1263
Onchocerca volvulus Histone deacetylase 10 homolog 0.0184 0.2976 0.3253
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0019 0.0176 0.0194
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0029 0.034 0.0303
Loa Loa (eye worm) hypothetical protein 0.0184 0.2976 0.327
Brugia malayi Cathepsin L-like precursor 0.0015 0.0096 0.0058
Entamoeba histolytica glycogen phosphorylase, putative 0.0051 0.072 0.1103
Trypanosoma cruzi histone deacetylase, putative 0.0184 0.2976 0.4591
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0029 0.034 0.0303
Onchocerca volvulus 0.0053 0.0744 0.0732
Brugia malayi Neurabin protein 1 0.0053 0.0744 0.0716
Echinococcus granulosus cathepsin l cysteine peptidase 0.0022 0.0219 0.0181
Loa Loa (eye worm) hypothetical protein 0.001 0.0019 0.0021
Onchocerca volvulus Cathepsin F homolog 0.0022 0.0219 0.0139
Plasmodium vivax peptide deformylase, putative 0.0241 0.3941 0.61
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0022 0.0219 0.024
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0022 0.0219 0.0352
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase 13, putative 0.0019 0.0176 0.0216
Mycobacterium ulcerans esterase/lipase LipP 0.0035 0.0442 0.0919
Leishmania major cathepsin L-like protease 0.0022 0.0219 0.0205
Loa Loa (eye worm) histone deacetylase 7A 0.0388 0.6436 0.7072
Schistosoma mansoni glycogen phosphorylase 0.0119 0.1867 0.1836
Trypanosoma cruzi Peptide deformylase 2, putative 0.0092 0.1409 0.2142
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0442 0.0711
Plasmodium vivax tyrosine kinase-like protein, putative 0.0053 0.0744 0.1103
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0022 0.0219 0.0219
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0019 0.0176 0.0224
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0022 0.0219 0.0352
Plasmodium falciparum U4/U6.U5 tri-snRNP-associated protein 2, putative 0.0019 0.0176 0.0216
Schistosoma mansoni histone deacetylase 0.0375 0.622 0.6206
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0022 0.0219 0.0352
Onchocerca volvulus 0.0022 0.0219 0.0139
Loa Loa (eye worm) hypothetical protein 0.0015 0.0096 0.0105
Brugia malayi sterile alpha and TIR motif containing protein 1 isoform a 0.0053 0.0744 0.0716
Schistosoma mansoni ubiquitin-specific peptidase 5 (C19 family) 0.0019 0.0176 0.0139
Schistosoma mansoni hypothetical protein 0.0053 0.0744 0.0708
Echinococcus multilocularis flap endonuclease 1 0.0025 0.0277 0.0278
Trypanosoma brucei histone deacetylase 4 0.0388 0.6436 1
Plasmodium falciparum protein kinase, putative 0.0053 0.0744 0.1103
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0011 0.0038 0.0061
Echinococcus multilocularis histone deacetylase 8 0.0184 0.2976 0.298
Trichomonas vaginalis brca1-associated protein, putative 0.0019 0.0176 0.0284
Entamoeba histolytica cysteine proteinase, putative 0.0015 0.0096 0.0093
Loa Loa (eye worm) histone deacetylase 0.0388 0.6436 0.7072
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0022 0.0219 0.0352
Toxoplasma gondii histone deacetylase HDAC4 0.0367 0.6076 0.9424
Toxoplasma gondii hypothetical protein 0.0241 0.3941 0.6014
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0022 0.0219 0.0352
Trypanosoma brucei histone deacetylase 3 0.0388 0.6436 1
Loa Loa (eye worm) flap endonuclease-1 0.0025 0.0277 0.0305
Leishmania major cathepsin L-like protease 0.0022 0.0219 0.0205
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0442 0.0406
Echinococcus granulosus nuclear receptor co repressor related ncor 0.0289 0.4758 0.4745
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0285 0.4682 0.7528
Onchocerca volvulus 0.0022 0.0219 0.0139
Echinococcus multilocularis tankyrase 0.0597 0.9986 1
Plasmodium vivax U4/U6.U5 tri-snRNP-associated protein 2, putative 0.0019 0.0176 0.0216
Loa Loa (eye worm) fibroinase 0.0022 0.0219 0.024
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0022 0.0219 0.0352
Mycobacterium ulcerans peptide deformylase 0.0241 0.3941 1
Schistosoma mansoni tripeptidyl-peptidase II (S08 family) 0.0264 0.4326 0.4304
Echinococcus granulosus histone deacetylase 8 0.0184 0.2976 0.2953
Trypanosoma brucei poly(adp-ribose) polymerase 0.0085 0.1295 0.1964
Trichomonas vaginalis conserved hypothetical protein 0.0085 0.1295 0.2081
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0029 0.034 0.0341
Plasmodium vivax vivapain-2 0.0022 0.0219 0.0282
Leishmania major cathepsin L-like protease 0.0022 0.0219 0.0205
Onchocerca volvulus 0.0035 0.0442 0.0391
Entamoeba histolytica poly(ADP-ribose) polymerase, putative 0.0085 0.1295 0.2032
Toxoplasma gondii histone deacetylase HDAC5 0.0185 0.299 0.4495
Mycobacterium ulcerans beta-lactamase 0.0035 0.0442 0.0919
Loa Loa (eye worm) subtilase 0.0264 0.4326 0.4753
Schistosoma mansoni cathepsin F (C01 family) 0.0015 0.0096 0.0058
Loa Loa (eye worm) glycogen phosphorylase 0.0119 0.1867 0.2052
Echinococcus granulosus stromal interaction molecule 1 0.0053 0.0744 0.0709
Toxoplasma gondii histone deacetylase HDAC1 0.0388 0.6436 1
Leishmania major cathepsin L-like protease 0.0022 0.0219 0.0205
Onchocerca volvulus 0.0021 0.021 0.0129
Schistosoma mansoni histone deacetylase hda2 0.0184 0.2976 0.2949
Toxoplasma gondii cathepsin CPL 0.0022 0.0219 0.0067
Onchocerca volvulus Cathepsin L homolog 0.0022 0.0219 0.0139
Trypanosoma cruzi Peptide deformylase 2, putative 0.0092 0.1409 0.2142
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 22 0.0019 0.0176 0.0139
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0035 0.0442 0.0919
Schistosoma mansoni brca1-associated protein (brap2) 0.0019 0.0176 0.0139
Echinococcus granulosus histone deacetylase 6 0.0407 0.6766 0.6764
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0015 0.0096 0.009
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0019 0.0176 0.0284
Loa Loa (eye worm) histone deacetylase 1 0.0375 0.622 0.6834
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0022 0.0219 0.0282
Loa Loa (eye worm) hypothetical protein 0.0021 0.021 0.023
Plasmodium falciparum cysteine proteinase falcipain 3 0.0022 0.0219 0.0282
Brugia malayi beta-lactamase family protein 0.0035 0.0442 0.041
Onchocerca volvulus 0.0022 0.0219 0.0139
Loa Loa (eye worm) CYP4Cod1 0.0014 0.0088 0.0097
Trypanosoma cruzi cytochrome P450, putative 0.0014 0.0088 0.0078
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0019 0.0176 0.0216
Echinococcus granulosus flap endonuclease 1 0.0025 0.0277 0.024
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0022 0.0219 0.0282
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0019 0.0176 0.0194
Trypanosoma cruzi histone deacetylase 1, putative 0.0375 0.622 0.9662
Loa Loa (eye worm) hypothetical protein 0.0026 0.0289 0.0317
Loa Loa (eye worm) ubiquitin specific peptidase 39 0.0019 0.0176 0.0194
Echinococcus granulosus u4:u6.u5 tri snrnp associated protein 2 0.0019 0.0176 0.0139
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0022 0.0219 0.0282
Onchocerca volvulus Tankyrase homolog 0.0536 0.8949 1
Trypanosoma cruzi Zn-finger in ubiquitin-hydrolases and other protein, putative 0.0019 0.0176 0.0216
Schistosoma mansoni hypothetical protein 0.0053 0.0744 0.0708
Schistosoma mansoni poly [ADP-ribose] polymerase 0.0085 0.1295 0.1261
Echinococcus multilocularis cathepsin L cysteine protease 0.0022 0.0219 0.0219
Echinococcus granulosus histone deacetylase 6 0.0388 0.6436 0.6432
Onchocerca volvulus 0.0029 0.034 0.0276
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0022 0.0219 0.0352
Schistosoma mansoni lip-related protein (liprin) alpha 0.0053 0.0744 0.0708
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0442 0.0711
Echinococcus multilocularis beta LACTamase domain containing family member 0.0035 0.0442 0.0443
Plasmodium falciparum histone deacetylase 2 0.0388 0.6436 1
Toxoplasma gondii histone deacetylase HDAC3 0.0375 0.622 0.9655
Echinococcus granulosus histone deacetylase 7 0.0388 0.6436 0.6432
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0285 0.4682 0.7528
Echinococcus multilocularis histone deacetylase 6 0.0388 0.6436 0.6446
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0022 0.0219 0.024
Brugia malayi Cathepsin L-like cysteine proteinase 0.0015 0.0096 0.0058
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase 5, putative 0.0019 0.0176 0.0224
Brugia malayi WGR domain containing protein 0.0085 0.1295 0.1274
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0285 0.4682 0.7528
Onchocerca volvulus Cathepsin L homolog 0.0022 0.0219 0.0139
Entamoeba histolytica cysteine protease, putative 0.0022 0.0219 0.0292
Brugia malayi Cathepsin L-like precursor 0.0022 0.0219 0.0183
Echinococcus multilocularis histone deacetylase 3 0.0375 0.622 0.6229
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0022 0.0219 0.0282
Plasmodium vivax histone deacetylase 1, putative 0.0375 0.622 0.9662
Loa Loa (eye worm) cytochrome P450 family protein 0.0014 0.0088 0.0097
Echinococcus granulosus histone deacetylase 0.0388 0.6436 0.6432
Chlamydia trachomatis peptide deformylase 0.0241 0.3941 1
Mycobacterium leprae conserved hypothetical protein 0.0035 0.0442 0.042
Trichomonas vaginalis conserved hypothetical protein 0.0085 0.1295 0.2081
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0029 0.034 0.0262
Echinococcus granulosus liprin beta 1 0.0053 0.0744 0.0709
Onchocerca volvulus Matrix metalloproteinase homolog 0.0047 0.0652 0.0629
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0285 0.4682 0.7528
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0035 0.0442 0.042
Trichomonas vaginalis flap endonuclease-1, putative 0.0025 0.0277 0.0446
Loa Loa (eye worm) hypothetical protein 0.0015 0.0096 0.0105
Schistosoma mansoni histone deacetylase hda2 0.0407 0.6766 0.6754
Trypanosoma cruzi histone deacetylase, putative 0.0388 0.6436 1
Loa Loa (eye worm) BRCA1-associated protein 2 containing protein 0.0019 0.0176 0.0194
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0019 0.0176 0.014
Brugia malayi Pre-SET motif family protein 0.0203 0.329 0.3298
Brugia malayi hypothetical protein 0.0053 0.0744 0.0716
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0015 0.0096 0.0154
Trichomonas vaginalis conserved hypothetical protein 0.0085 0.1295 0.2081
Plasmodium falciparum histone deacetylase, putative 0.0388 0.6436 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0022 0.0219 0.0352
Trichomonas vaginalis histone deacetylase, putative 0.0375 0.622 1
Trichomonas vaginalis conserved hypothetical protein 0.0085 0.1295 0.2081
Brugia malayi hypothetical protein 0.0053 0.0744 0.0716
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0022 0.0219 0.0282
Trichomonas vaginalis histone deacetylase, putative 0.0375 0.622 1
Loa Loa (eye worm) hypothetical protein 0.0053 0.0744 0.0817
Schistosoma mansoni histone deacetylase 0.0375 0.622 0.6206
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0139 0.2209 0.5257
Loa Loa (eye worm) histone deacetylase 11 0.0367 0.6076 0.6676
Entamoeba histolytica cysteine proteinase, putative 0.0022 0.0219 0.0292
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0744 0.1196
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0442 0.0406
Trypanosoma brucei hypothetical protein, conserved 0.0035 0.0442 0.0631
Loa Loa (eye worm) hypothetical protein 0.0053 0.0744 0.0817
Echinococcus multilocularis Peptidase S8 S53, subtilisin kexin sedolisin 0.0099 0.1524 0.1526
Onchocerca volvulus Uncharacterized RING finger protein homolog 0.0019 0.0176 0.0091
Echinococcus multilocularis histone deacetylase 6 0.0407 0.6766 0.6776
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0285 0.4682 0.7528
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0022 0.0219 0.0352
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0022 0.0219 0.0352
Trichomonas vaginalis ankyrin repeat domain protein, putative 0.001 0.0022 0.0036
Loa Loa (eye worm) cytochrome P450 family protein 0.0014 0.0088 0.0097
Loa Loa (eye worm) hypothetical protein 0.0035 0.0442 0.0486
Schistosoma mansoni histone deacetylase 4 5 0.0388 0.6436 0.6423
Brugia malayi histone deacetylase 3 (HD3) 0.0375 0.622 0.6269
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0029 0.034 0.0303
Loa Loa (eye worm) toll and interleukin 1 receptor domain-containing protein isoform f 0.0053 0.0744 0.0817
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0019 0.0176 0.0284
Trichomonas vaginalis BRCA1-associated protein, putative 0.0019 0.0176 0.0284
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0139 0.2209 0.5504
Echinococcus multilocularis cysteine protease 0.0022 0.0219 0.0219
Mycobacterium ulcerans lipase LipD 0.0035 0.0442 0.0919
Onchocerca volvulus 0.0035 0.0442 0.0391
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0022 0.0219 0.0282
Plasmodium vivax histone deacetylase, putative 0.0388 0.6436 1
Leishmania major hypothetical protein, conserved 0.0019 0.0176 0.0139
Loa Loa (eye worm) hypothetical protein 0.0015 0.0096 0.0105

Activities

Activity type Activity value Assay description Source Reference
Antitumor activity (functional) = 0.88 g Antitumor activity evaluated as tumor weight on day 21 of Meth A Fibrosarcoma in BALB/c mice at a dose of 50 mg/kg administered intravenously on day 5 ChEMBL. 14971908
Antitumor activity (functional) = 0.88 g Antitumor activity evaluated as tumor weight on day 21 of Meth A Fibrosarcoma in BALB/c mice at a dose of 100 mg/kg administered intravenously on day 5 ChEMBL. 14971908
Antitumor activity (functional) = 0.93 g Antitumor activity evaluated as tumor weight on day 21 of Meth A Fibrosarcoma in BALB/c mice at a dose of 25 mg/kg administered intravenously on day 5 ChEMBL. 14971908
Inhibition rate (functional) = 62.3 % Inhibition rate of tumor growth at 25 mg/kg single iv administration against Meth A fibrosarcoma cells in BALB/c Mice ChEMBL. 14971908
Inhibition rate (functional) = 64 % Inhibition rate of tumor growth at 50 mg/kg single iv administration against Meth A fibrosarcoma cells in BALB/c Mice ChEMBL. 14971908
Inhibition rate (functional) = 69.3 % Inhibition rate of tumor growth at 100 mg/kg single iv administration against Meth A fibrosarcoma cells in BALB/c Mice ChEMBL. 14971908

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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