Detailed information for compound 1467398

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 238.28 | Formula: C13H18O4
  • H donors: 2 H acceptors: 3 LogP: 3.18 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCC(C(=O)c1c(O)cc(c(c1O)C)OC)C
  • InChi: 1S/C13H18O4/c1-5-7(2)12(15)11-9(14)6-10(17-4)8(3)13(11)16/h6-7,14,16H,5H2,1-4H3
  • InChiKey: HDRPUFIQLCTRLW-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Treponema pallidum alginate O-acetylation protein (algI) 0.0142 0.0019 0.5
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0564 0.0296 0.4116
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0283 0.0111 0.139
Brugia malayi FAT domain containing protein 0.0489 0.0246 0.2115
Trichomonas vaginalis PIKK family atypical protein kinase 0.1155 0.0683 0.9886
Loa Loa (eye worm) kelch domain-containing protein family protein 0.0297 0.0121 0.1035
Echinococcus multilocularis phosphatidylinositol 4 kinase alpha 0.0283 0.0111 0.0092
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.1167 0.0691 0.1999
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.1188 0.0704 0.2039
Leishmania major hypothetical protein, unknown function 0.0231 0.0077 0.0163
Trypanosoma cruzi GUP1, putative 0.0142 0.0019 0.0048
Giardia lamblia Phosphoinositide-3-kinase, class 3 0.0296 0.012 0.0692
Echinococcus multilocularis Zinc finger, PHD finger 0.0283 0.0111 0.0092
Schistosoma mansoni sterol O-acyltransferase 1 0.1455 0.0879 1
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0348 0.0154 0.2006
Trichomonas vaginalis PIKK family atypical protein kinase 0.1148 0.0678 0.9819
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0348 0.0154 0.2006
Trichomonas vaginalis PIKK family atypical protein kinase 0.1155 0.0683 0.9886
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0663 0.036 0.3092
Trichomonas vaginalis PIKK family atypical protein kinase 0.0417 0.0199 0.2679
Entamoeba histolytica phosphatidylinositol 4-kinase, putative 0.0283 0.0111 0.1374
Trichomonas vaginalis PIKK family atypical protein kinase 0.1167 0.0691 1
Schistosoma mansoni phosphatidylinositol 4-kinase type-II 0.0231 0.0077 0.0677
Trichomonas vaginalis PIKK family atypical protein kinase 0.1146 0.0677 0.9795
Trichomonas vaginalis PIKK family atypical protein kinase 0.0678 0.037 0.5229
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0231 0.0077 0.6313
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.1167 0.0691 1
Loa Loa (eye worm) hypothetical protein 0.0648 0.035 0.3008
Trichomonas vaginalis PIKK family atypical protein kinase 0.1158 0.0684 0.9909
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0348 0.0154 0.2006
Brugia malayi Integrin beta pat-3 precursor 0.1891 0.1165 1
Loa Loa (eye worm) hypothetical protein 0.0432 0.0209 0.1792
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0283 0.0111 0.1072
Echinococcus multilocularis 0.0231 0.0077 0.0058
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0804 0.0452 0.5036
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0283 0.0111 0.1374
Loa Loa (eye worm) phosphatidylinositol 3 0.0739 0.041 0.3519
Trypanosoma cruzi phosphatidylinositol kinase, putative 0.0231 0.0077 0.0218
Trichomonas vaginalis PIKK family atypical protein kinase 0.1146 0.0677 0.9796
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0529 0.0273 0.3779
Echinococcus granulosus phosphatidylinositol 3 kinase catalytic subunit 0.0283 0.0111 0.0092
Trichomonas vaginalis PIKK family atypical protein kinase 0.0231 0.0077 0.0867
Loa Loa (eye worm) diacylglycerol acyltransferase 0.0142 0.0019 0.0165
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0283 0.0111 0.1374
Trichomonas vaginalis PIKK family atypical protein kinase 0.1137 0.0671 0.9705
Giardia lamblia GTOR 0.1167 0.0691 1
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.0648 0.035 0.0332
Entamoeba histolytica protein kinase rad3, putative 0.0648 0.035 0.4934
Plasmodium falciparum phosphatidylinositol 4-kinase 0.0231 0.0077 0.6313
Trichomonas vaginalis PIKK family atypical protein kinase 0.1137 0.0671 0.9705
Brugia malayi phosphatidylinositol 4-kinase, catalytic, alpha polypeptide 0.0283 0.0111 0.0957
Trichomonas vaginalis PIKK family atypical protein kinase 0.1158 0.0684 0.9909
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0231 0.0077 0.0665
Trypanosoma cruzi hypothetical protein, conserved 0.537 0.3444 1
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0348 0.0154 0.2006
Echinococcus granulosus sterol O acyltransferase 1 0.1455 0.0879 0.0862
Echinococcus multilocularis phosphatidylinositol 4,5 bisphosphate 3 kinase 0.0804 0.0452 0.0434
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0447 0.0219 0.188
Trichomonas vaginalis PIKK family atypical protein kinase 0.1148 0.0678 0.9819
Loa Loa (eye worm) hypothetical protein 0.0142 0.0019 0.0165
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0432 0.0209 0.0599
Trichomonas vaginalis conserved hypothetical protein 0.072 0.0398 0.5639
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.1188 0.0704 0.0686
Trichomonas vaginalis conserved hypothetical protein 0.0417 0.0199 0.2679
Loa Loa (eye worm) membrane bound O-acyltransferase domain containing 1 0.0142 0.0019 0.0165
Entamoeba histolytica hypothetical protein 0.0231 0.0077 0.0867
Trichomonas vaginalis PIKK family atypical protein kinase 0.1155 0.0683 0.9886
Trichomonas vaginalis PIKK family atypical protein kinase 0.1146 0.0677 0.9796
Trypanosoma brucei target of rapamycin kinase 3, putative 0.1158 0.0684 0.991
Loa Loa (eye worm) phosphatidylinositol 3 0.1148 0.0678 0.5819
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.1137 0.0671 0.9705
Loa Loa (eye worm) MBOAT family protein 0.0142 0.0019 0.0165
Schistosoma mansoni hypothetical protein 0.0231 0.0077 0.0677
Echinococcus multilocularis DNA dependent protein kinase catalytic subunit 1.5379 1 1
Brugia malayi MBOAT family protein 0.0142 0.0019 0.0165
Schistosoma mansoni hypothetical protein 0.0489 0.0246 0.2641
Entamoeba histolytica hypothetical protein 0.0231 0.0077 0.0867
Loa Loa (eye worm) hypothetical protein 0.0447 0.0219 0.188
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0283 0.0111 0.139
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.0659 0.0358 0.504
Leishmania major phosphatidylinositol 3-related kinase, putative 0.1148 0.0678 0.1842
Brugia malayi Kelch motif family protein 0.0297 0.0121 0.1035
Echinococcus multilocularis PIK kinase, FAT and Armadillo domain containing protein 0.0489 0.0246 0.0228
Mycobacterium leprae conserved hypothetical protein 0.0231 0.0077 0.5
Brugia malayi Hhat protein 0.0142 0.0019 0.0165
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.1148 0.0678 0.9811
Trichomonas vaginalis PIKK family atypical protein kinase 0.0231 0.0077 0.0867
Trichomonas vaginalis PIKK family atypical protein kinase 0.1148 0.0678 0.9811
Trichomonas vaginalis PIKK family atypical protein kinase 0.0669 0.0364 0.5138
Loa Loa (eye worm) integrin beta-2 0.1891 0.1165 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.1146 0.0677 0.9795
Loa Loa (eye worm) hhat protein 0.0142 0.0019 0.0165
Leishmania major phosphatidylinositol 4-kinase alpha, putative 0.0283 0.0111 0.0258
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0729 0.0404 0.5729
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.1167 0.0691 0.7804
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0348 0.0154 0.1321
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.1167 0.0691 1
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0231 0.0077 0.0867
Brugia malayi MBOAT family protein 0.0142 0.0019 0.0165
Trypanosoma cruzi glycerol uptake protein, putative 0.0142 0.0019 0.0048
Entamoeba histolytica hypothetical protein 0.0564 0.0296 0.4116
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.1188 0.0704 0.0686
Trichomonas vaginalis PIKK family atypical protein kinase 0.0666 0.0363 0.5115
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.1158 0.0684 0.1861
Leishmania major phosphatidylinositol kinase, putative 0.0231 0.0077 0.0163
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0629 0.0338 0.4749
Entamoeba histolytica hypothetical protein 0.0663 0.036 0.5078
Echinococcus granulosus phosphatidylinositol 4 phosphate 3 kinase C2 0.0447 0.0219 0.02
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0629 0.0338 0.4749
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.1167 0.0691 0.1999
Loa Loa (eye worm) phosphatidylinositol 3 0.0231 0.0077 0.0665
Brugia malayi MBOAT family protein 0.0142 0.0019 0.0165
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0231 0.0077 0.0218
Trichomonas vaginalis PIKK family atypical protein kinase 0.0666 0.0363 0.5115
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0231 0.0077 0.0058
Loa Loa (eye worm) phosphatidylinositol kinase 0.0231 0.0077 0.0665
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0629 0.0338 0.0975
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.1167 0.0691 0.5928
Loa Loa (eye worm) hypothetical protein 0.0297 0.0121 0.1035
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0663 0.036 0.5078
Trypanosoma cruzi target of rapamycin kinase 3 0.1158 0.0684 0.1982
Trichomonas vaginalis PIKK family atypical protein kinase 0.0659 0.0358 0.504
Entamoeba histolytica phosphatidylinositol-4,5-bisphosphate 3-kinase, putative 0.0283 0.0111 0.1374
Toxoplasma gondii target of rapamycin (TOR), putative 0.1155 0.0683 1
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0231 0.0077 0.0867
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0648 0.035 0.3008
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0529 0.0273 0.3779
Trypanosoma cruzi GUP1, putative 0.0142 0.0019 0.0048
Entamoeba histolytica phosphatidylinositol 3-kinase 1, putative 0.0398 0.0187 0.2494
Echinococcus granulosus phosphatidylinositol 4 kinase beta 0.0231 0.0077 0.0058
Trypanosoma cruzi glycerol uptake protein, putative 0.0142 0.0019 0.0048
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0231 0.0077 0.6313
Trichomonas vaginalis PIKK family atypical protein kinase 0.1158 0.0684 0.9909
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0231 0.0077 0.0058
Echinococcus multilocularis integrin beta 2 0.1385 0.0833 0.0815
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.1188 0.0704 0.2039
Loa Loa (eye worm) phosphatidylinositol 3 0.0231 0.0077 0.0665
Brugia malayi MBOAT family protein 0.0142 0.0019 0.0165
Leishmania major phosphatidylinositol 3-kinase, putative 0.0283 0.0111 0.0258
Echinococcus multilocularis phosphatidylinositol 4 phosphate 3 kinase C2 0.0447 0.0219 0.02
Echinococcus granulosus PIK kinase FAT and Armadillo domain containing protein 0.0489 0.0246 0.0228
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0629 0.0338 0.2902
Leishmania major phosphatidylinositol kinase related protein, putative 0.0246 0.0087 0.019
Onchocerca volvulus 0.0231 0.0077 1
Echinococcus granulosus phosphatidylinositol 45 bisphosphate 3 kinase 0.0804 0.0452 0.0434
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0231 0.0077 0.0677
Trichomonas vaginalis PIKK family atypical protein kinase 0.1137 0.0671 0.9705
Loa Loa (eye worm) hypothetical protein 0.1455 0.0879 0.7549
Plasmodium vivax hypothetical protein 0.0231 0.0077 0.6313
Toxoplasma gondii FATC domain-containing protein 0.0663 0.036 0.5137
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0231 0.0077 0.0218
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.1167 0.0691 1
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.1167 0.0691 0.1877
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0663 0.036 0.3963
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0231 0.0077 0.0058
Brugia malayi phosphoinositide 3'-hydroxykinase p110-alpha subunit, putative 0.0175 0.0041 0.0348
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.1188 0.0704 0.7962
Trichomonas vaginalis PIKK family atypical protein kinase 0.0663 0.036 0.5078
Plasmodium vivax phosphatidylinositol 3- and 4-kinase, putative 0.0231 0.0077 0.6313
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0231 0.0077 0.0877
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0231 0.0077 0.0665
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.1167 0.0691 0.0673
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0246 0.0087 0.0246
Trypanosoma cruzi phosphatidylinositol 3-kinase vps34-like 0.0348 0.0154 0.044
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.1188 0.0704 0.6044
Echinococcus granulosus serine protein kinase ATM 0.0663 0.036 0.0342
Loa Loa (eye worm) phosphatidylinositol 3 0.1167 0.0691 0.5928
Trichomonas vaginalis phosphatidylinositol 4-kinase, putative 0.0283 0.0111 0.1374
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0348 0.0154 0.1566
Trichomonas vaginalis PIKK family atypical protein kinase 0.1155 0.0683 0.9886
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0283 0.0111 0.0316
Brugia malayi hypothetical protein 0.0297 0.0121 0.1035
Trypanosoma brucei phosphatidylinositol 3-kinase catalytic subunit, putative 0.0231 0.0077 0.0867
Loa Loa (eye worm) phosphatidylinositol 3 0.0231 0.0077 0.0665
Trichomonas vaginalis PIKK family atypical protein kinase 0.1167 0.0691 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.1158 0.0684 0.9909
Plasmodium vivax phosphatidylinositol 3-kinase, putative 0.0283 0.0111 1
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.1167 0.0691 0.1877
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0231 0.0077 0.0218
Trichomonas vaginalis PIKK family atypical protein kinase 0.1155 0.0683 0.9886
Echinococcus granulosus integrin beta 2 0.1385 0.0833 0.0815
Trichomonas vaginalis PIKK family atypical protein kinase 0.1167 0.0691 1
Leishmania major phosphatidylinositol 3-kinase, putative 0.1137 0.0671 0.1822
Brugia malayi MBOAT family protein 0.0142 0.0019 0.0165
Loa Loa (eye worm) hypothetical protein 0.0142 0.0019 0.0165
Loa Loa (eye worm) hypothetical protein 0.0182 0.0045 0.0387
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0629 0.0338 0.4749
Entamoeba histolytica hypothetical protein 0.0231 0.0077 0.0867
Loa Loa (eye worm) MBOAT family protein 0.0142 0.0019 0.0165
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0231 0.0077 0.0867
Echinococcus granulosus serine:threonine protein kinase SMG1 0.0648 0.035 0.0332
Trichomonas vaginalis PIKK family atypical protein kinase 0.0741 0.0411 0.5843
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit gamma, putative 0.0629 0.0338 0.4749
Leishmania major phosphatidylinositol 4-kinase, putative 0.0231 0.0077 0.0163
Leishmania major hypothetical protein, conserved 0.5601 0.3595 1
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0283 0.0111 0.0316
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0382 0.0177 0.2343
Loa Loa (eye worm) phosphatidylinositol 4-kinase type 3 alpha isoform 1 0.0283 0.0111 0.0957
Schistosoma mansoni integrin beta subunit 0.1088 0.0639 0.7201
Trichomonas vaginalis PIKK family atypical protein kinase 0.1146 0.0677 0.9796
Plasmodium falciparum phosphatidylinositol 3-kinase 0.0283 0.0111 1
Echinococcus multilocularis serine protein kinase ATM 0.0663 0.036 0.0342
Loa Loa (eye worm) MBOAT family protein 0.0142 0.0019 0.0165
Trichomonas vaginalis PIKK family atypical protein kinase 0.024 0.0084 0.0958
Trichomonas vaginalis conserved hypothetical protein 0.0489 0.0246 0.3384
Trichomonas vaginalis PIKK family atypical protein kinase 0.1155 0.0683 0.9886
Loa Loa (eye worm) hhat protein 0.0142 0.0019 0.0165
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.025 0.009 0.1049
Trypanosoma cruzi glycerol uptake protein, putative 0.0142 0.0019 0.0048
Loa Loa (eye worm) hypothetical protein 0.0142 0.0019 0.0165
Trichomonas vaginalis PIKK family atypical protein kinase 0.1146 0.0677 0.9795
Loa Loa (eye worm) hypothetical protein 0.1313 0.0786 0.675
Loa Loa (eye worm) phosphatidylinositol 3 0.0117 0.0003 0.0022
Trypanosoma brucei phosphatidylinositol 4-kinase alpha, putative 0.0283 0.0111 0.1374
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0348 0.0154 0.2006
Trichomonas vaginalis PIKK family atypical protein kinase 0.0648 0.035 0.4934
Schistosoma mansoni fkbp-rapamycin associated protein 0.0648 0.035 0.385
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0348 0.0154 0.2006
Echinococcus granulosus phosphatidylinositol 4 kinase alpha 0.0283 0.0111 0.0092
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0231 0.0077 0.0058
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.1167 0.0691 1
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0663 0.036 0.1039
Loa Loa (eye worm) hypothetical protein 0.0489 0.0246 0.2115
Schistosoma mansoni phosphatidylinositol 3-kinase class 0.0231 0.0077 0.0677
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0231 0.0077 0.0877
Giardia lamblia Phosphoinositide-3-kinase, catalytic, alpha polypeptide 0.0465 0.023 0.2496
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0231 0.0077 0.0877
Brugia malayi diacylglycerol acyltransferase 0.0142 0.0019 0.0165
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0629 0.0338 0.0975
Entamoeba histolytica phosphatidylinositol 3-kinase 3, putative 0.0231 0.0077 0.0867
Toxoplasma gondii non-specific serine/threonine protein kinase 0.072 0.0398 0.5703
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0648 0.035 0.1011
Loa Loa (eye worm) hypothetical protein 0.0231 0.0077 0.0665
Plasmodium falciparum phosphatidylinositol 3- and 4-kinase, putative 0.0231 0.0077 0.6313
Trichomonas vaginalis PIKK family atypical protein kinase 0.1158 0.0684 0.9909
Mycobacterium tuberculosis Conserved hypothetical protein 0.0231 0.0077 0.5
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.1167 0.0691 0.0673
Echinococcus multilocularis sterol O acyltransferase 1 0.1455 0.0879 0.0862
Loa Loa (eye worm) phosphatidylinositol 3 0.0231 0.0077 0.0665
Trichomonas vaginalis PIKK family atypical protein kinase 0.1155 0.0683 0.9886
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0283 0.0111 0.1072
Loa Loa (eye worm) hypothetical protein 0.072 0.0398 0.3414
Plasmodium vivax hypothetical protein, conserved 0.0231 0.0077 0.6313
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0231 0.0077 0.0665
Trichomonas vaginalis PIKK family atypical protein kinase 0.0666 0.0363 0.5115
Trichomonas vaginalis PIKK family atypical protein kinase 0.1146 0.0677 0.9796
Onchocerca volvulus 0.0231 0.0077 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.1137 0.0671 0.9705

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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