Detailed information for compound 1468898

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 490.548 | Formula: C28H30N2O6
  • H donors: 0 H acceptors: 4 LogP: 2.46 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: COC(=O)[C@@]12CCCCN1[C@@H]([C@H]1[C@@H]2C(=O)N(C1=O)C)c1ccc(c(c1)OC)c1ccc(cc1)C(=O)C
  • InChi: 1S/C28H30N2O6/c1-16(31)17-7-9-18(10-8-17)20-12-11-19(15-21(20)35-3)24-22-23(26(33)29(2)25(22)32)28(27(34)36-4)13-5-6-14-30(24)28/h7-12,15,22-24H,5-6,13-14H2,1-4H3/t22-,23-,24-,28+/m1/s1
  • InChiKey: ZOSUAHGKXZVBFY-MUCKBHKGSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0022 0.0109 0.0109
Loa Loa (eye worm) G-protein coupled receptor 0.0022 0.0109 0.0095
Brugia malayi Pre-SET motif family protein 0.0033 0.0202 0.0202
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0021 0.01 0.0086
Loa Loa (eye worm) hypothetical protein 0.0022 0.0109 0.0095
Brugia malayi hypothetical protein 0.004 0.026 0.026
Loa Loa (eye worm) hypothetical protein 0.0022 0.0109 0.0095
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.0524 1
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.004 0.026 0.026
Schistosoma mansoni biogenic amine (5HT) receptor 0.0022 0.0109 0.0109
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0022 0.0109 0.0109
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0022 0.0109 0.0109
Loa Loa (eye worm) hypothetical protein 0.0033 0.0202 0.0188
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0022 0.0109 0.0109
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0041 0.0269 0.0269
Brugia malayi acetyltransferase, GNAT family protein 0.016 0.1295 0.1295
Entamoeba histolytica hypothetical protein 0.004 0.026 0.8984
Echinococcus multilocularis serotonin receptor 0.0022 0.0109 0.0109
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.0109 0.0109
Onchocerca volvulus 0.0261 0.2169 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0041 0.0269 0.1242
Brugia malayi G protein-coupled receptor F59B2.13 0.0022 0.0109 0.0109
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0041 0.0269 0.9313
Echinococcus granulosus neuropeptide receptor 0.0022 0.0109 0.0109
Loa Loa (eye worm) hypothetical protein 0.0022 0.0109 0.0095
Echinococcus multilocularis cysteine protease 0.0018 0.0077 0.0077
Treponema pallidum grpE protein (grpE) 0.0034 0.0215 1
Onchocerca volvulus 0.0018 0.0077 0.0245
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.0109 0.0109
Echinococcus granulosus intermediate filament protein 0.003 0.0174 0.0174
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0022 0.0109 0.0109
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0202 0.0202
Echinococcus multilocularis neuropeptide receptor A26 0.0022 0.0109 0.0109
Echinococcus multilocularis neuropeptide receptor 0.0022 0.0109 0.0109
Loa Loa (eye worm) hypothetical protein 0.0022 0.0109 0.0095
Schistosoma mansoni neuropeptide F-like receptor 0.0022 0.0109 0.0109
Echinococcus granulosus alpha 1A adrenergic receptor 0.0022 0.0109 0.0109
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0022 0.0109 0.0095
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0077 0.0356
Schistosoma mansoni regulator of G protein signaling 0.0021 0.01 0.01
Trichomonas vaginalis set domain proteins, putative 0.0261 0.2169 1
Loa Loa (eye worm) hypothetical protein 0.0022 0.0109 0.0095
Trypanosoma cruzi cysteine peptidase, putative 0.0018 0.0077 0.1472
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0077 0.0356
Loa Loa (eye worm) hypothetical protein 0.0022 0.0109 0.0095
Schistosoma mansoni hypothetical protein 0.1169 1 1
Schistosoma mansoni regulator of G protein signaling 0.0021 0.01 0.01
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0269 0.1242
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0018 0.0077 0.1194
Schistosoma mansoni serine/threonine protein kinase 0.0021 0.01 0.01
Echinococcus multilocularis neuropeptide FF receptor 2 0.0022 0.0109 0.0109
Echinococcus granulosus rhodopsin orphan GPCR 0.0022 0.0109 0.0109
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.01 0.0462
Schistosoma mansoni cathepsin F (C01 family) 0.0018 0.0077 0.0077
Brugia malayi putative neuropeptide receptor NPR1 0.0022 0.0109 0.0109
Echinococcus granulosus dro:myosuppressin receptor 0.0022 0.0109 0.0109
Brugia malayi G-protein coupled receptor 0.0022 0.0109 0.0109
Echinococcus granulosus neuropeptides capa receptor 0.0022 0.0109 0.0109
Brugia malayi Dopamine receptor protein 2 0.0022 0.0109 0.0109
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0018 0.0077 0.0077
Onchocerca volvulus 0.0018 0.0077 0.0245
Echinococcus granulosus G protein coupled receptor 139 0.0022 0.0109 0.0109
Brugia malayi Cathepsin L-like precursor 0.0018 0.0077 0.0077
Schistosoma mansoni amine GPCR 0.0022 0.0109 0.0109
Plasmodium falciparum histone acetyltransferase GCN5 0.0043 0.0289 0.4476
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0047 0.0323 0.1489
Loa Loa (eye worm) hypothetical protein 0.0022 0.0109 0.0095
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0077 0.0356
Onchocerca volvulus Cathepsin L homolog 0.0018 0.0077 0.0245
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0022 0.0109 0.0109
Brugia malayi hypothetical protein 0.0021 0.01 0.01
Loa Loa (eye worm) hypothetical protein 0.0012 0.0025 0.0011
Schistosoma mansoni axis inhibition protein axin 0.0021 0.01 0.01
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0022 0.0106 0.1533
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0022 0.0109 0.0109
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0202 0.0202
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0047 0.0323 0.4916
Echinococcus granulosus tm gpcr rhodopsin 0.0022 0.0109 0.0109
Loa Loa (eye worm) hypothetical protein 0.0021 0.01 0.0086
Echinococcus granulosus regulator of G protein signaling 3 0.0021 0.01 0.01
Trypanosoma cruzi cruzipain precursor, putative 0.007 0.0524 1
Schistosoma mansoni axis inhibition protein axin 0.0021 0.01 0.01
Echinococcus multilocularis regulator of G protein signaling 7 0.0021 0.01 0.01
Echinococcus granulosus indoleamine 23 dioxygenase 2 0.1169 1 1
Onchocerca volvulus 0.0022 0.0109 0.0392
Brugia malayi Cathepsin L-like precursor 0.0018 0.0077 0.0077
Echinococcus granulosus neuropeptide receptor 0.0525 0.4446 0.4446
Echinococcus multilocularis musashi 0.003 0.0174 0.0174
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0077 0.0356
Schistosoma mansoni growth hormone secretagogue receptor 0.0022 0.0109 0.0109
Mycobacterium tuberculosis Probable GrpE protein (HSP-70 cofactor) 0.0021 0.0102 0.0094
Onchocerca volvulus Cathepsin L homolog 0.0018 0.0077 0.0245
Brugia malayi hypothetical protein 0.0022 0.0109 0.0109
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0022 0.0109 0.0109
Plasmodium vivax ATP-dependent DNA helicase Q1, putative 0.0011 0.001 0.0161
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0084 0.0646 1
Giardia lamblia Sgs1 DNA helicase, putative 0.0022 0.0106 0.2925
Schistosoma mansoni cathepsin F (C01 family) 0.0018 0.0077 0.0077
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0033 0.0202 0.0202
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0022 0.0109 0.0095
Loa Loa (eye worm) acetyltransferase 0.016 0.1295 0.1283
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0041 0.0269 0.0269
Echinococcus multilocularis regulator of G protein signaling 3 0.0021 0.01 0.01
Schistosoma mansoni myosin xvIII 0.0022 0.0109 0.0109
Wolbachia endosymbiont of Brugia malayi molecular chaperone GrpE (heat shock protein) 0.0034 0.0215 1
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0021 0.0097 0.1845
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0022 0.0106 0.1646
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0047 0.0323 0.4998
Brugia malayi G protein-coupled receptor 0.0022 0.0109 0.0109
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0021 0.0097 0.2553
Echinococcus granulosus rhodopsin orphan GPCR 0.0022 0.0109 0.0109
Leishmania major cathepsin L-like protease 0.0018 0.0077 0.0941
Loa Loa (eye worm) hypothetical protein 0.0022 0.0109 0.0095
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0011 0.0014 0.0268
Loa Loa (eye worm) hypothetical protein 0.0022 0.0109 0.0095
Loa Loa (eye worm) neuropeptide F receptor 0.0022 0.0109 0.0095
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0084 0.0646 0.0646
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0041 0.0269 0.0269
Schistosoma mansoni hypothetical protein 0.0187 0.1528 0.1528
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0018 0.0077 0.1194
Brugia malayi Cathepsin L-like precursor 0.0018 0.0077 0.0077
Echinococcus multilocularis g protein coupled receptor 0.0022 0.0109 0.0109
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0021 0.0097 0.1845
Brugia malayi Serotonin receptor 0.0022 0.0109 0.0109
Echinococcus granulosus neuropeptide Y receptor 0.0022 0.0109 0.0109
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.0109 0.0109
Entamoeba histolytica hypothetical protein 0.004 0.026 0.8984
Echinococcus granulosus neuropeptides capa receptor 0.0022 0.0109 0.0109
Echinococcus granulosus axis inhibition protein axin 0.0021 0.01 0.01
Onchocerca volvulus 0.0022 0.0109 0.0392
Schistosoma mansoni cathepsin F (C01 family) 0.0012 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0022 0.0109 0.0095
Schistosoma mansoni biogenic amine receptor 0.0022 0.0109 0.0109
Loa Loa (eye worm) hypothetical protein 0.0021 0.01 0.0086
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.0109 0.0109
Brugia malayi A-kinase anchor protein 10, precursor 0.0021 0.01 0.01
Brugia malayi Papain family cysteine protease containing protein 0.0018 0.0077 0.0077
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0021 0.01 0.0086
Brugia malayi Melatonin receptor type 1A 0.0022 0.0109 0.0109
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.0524 1
Entamoeba histolytica cysteine proteinase, putative 0.0018 0.0077 0.2666
Loa Loa (eye worm) hypothetical protein 0.0084 0.0646 0.0633
Loa Loa (eye worm) hypothetical protein 0.0022 0.0106 0.0092
Leishmania major cathepsin L-like protease 0.0018 0.0077 0.0941
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.0109 0.0109
Schistosoma mansoni DNA helicase recq5 0.0022 0.0106 0.0106
Onchocerca volvulus 0.0022 0.0109 0.0392
Brugia malayi Pre-SET motif family protein 0.0229 0.1895 0.1895
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0022 0.0109 0.0109
Loa Loa (eye worm) hypothetical protein 0.0022 0.0109 0.0095
Onchocerca volvulus 0.0022 0.0109 0.0392
Echinococcus granulosus orexin receptor type 2 0.0022 0.0109 0.0109
Echinococcus granulosus allatostatin A receptor 0.0022 0.0109 0.0109
Schistosoma mansoni ap endonuclease 0.0021 0.0097 0.0097
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0041 0.0269 0.0269
Schistosoma mansoni hypothetical protein 0.1169 1 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.0524 1
Brugia malayi hypothetical protein 0.0022 0.0109 0.0109
Loa Loa (eye worm) hypothetical protein 0.0022 0.0109 0.0095
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0022 0.0109 0.0109
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0011 0.0014 0.0268
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.0109 0.0109
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0022 0.0109 0.0109
Brugia malayi hypothetical protein 0.0022 0.0109 0.0109
Schistosoma mansoni histamine h1 receptor 0.0022 0.0109 0.0109
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0032 0.0191 0.0191
Onchocerca volvulus 0.0034 0.0215 0.0886
Loa Loa (eye worm) hypothetical protein 0.0018 0.0077 0.0063
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0229 0.1895 0.1884
Onchocerca volvulus Cathepsin F homolog 0.0018 0.0077 0.0245
Entamoeba histolytica hypothetical protein 0.0021 0.01 0.3463
Loa Loa (eye worm) hypothetical protein 0.0022 0.0109 0.0095
Leishmania major cathepsin L-like protease 0.007 0.0524 1
Schistosoma mansoni hypothetical protein 0.0187 0.1528 0.1528
Onchocerca volvulus 0.0033 0.0202 0.0826
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0021 0.0097 0.0083
Loa Loa (eye worm) hypothetical protein 0.0022 0.0109 0.0095
Schistosoma mansoni neuropeptide receptor 0.0022 0.0109 0.0109
Brugia malayi hypothetical protein 0.0022 0.0109 0.0109
Brugia malayi neuropeptide F receptor 0.0022 0.0109 0.0109
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0022 0.0109 0.0109
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0022 0.0109 0.0109
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0022 0.0106 0.1509
Brugia malayi Tachykinin-like peptides receptor 99D 0.0022 0.0109 0.0109
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0077 0.0356
Entamoeba histolytica cysteine proteinase, putative 0.0018 0.0077 0.2666
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0022 0.0109 0.0109
Echinococcus multilocularis neuropeptides capa receptor 0.0022 0.0109 0.0109
Onchocerca volvulus 0.0022 0.0109 0.0392
Onchocerca volvulus 0.0018 0.0077 0.0245
Leishmania major cathepsin L-like protease 0.0018 0.0077 0.0941
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0077 0.0356
Brugia malayi Cathepsin L-like precursor 0.0018 0.0077 0.0077
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0077 0.0356
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0077 0.0356
Onchocerca volvulus 0.0018 0.0077 0.0245
Plasmodium falciparum cysteine proteinase falcipain 3 0.0018 0.0077 0.1194
Brugia malayi Cathepsin L-like precursor 0.0012 0.0025 0.0025
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0012 0.0025 0.0113
Echinococcus granulosus neuropeptide Y receptor 0.0022 0.0109 0.0109
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0041 0.0269 0.1242
Brugia malayi hypothetical protein 0.0022 0.0109 0.0109
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.0022 0.011 0.011
Loa Loa (eye worm) hypothetical protein 0.0021 0.01 0.0086
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0021 0.01 0.0462
Echinococcus multilocularis neuropeptide Y receptor 0.0022 0.0109 0.0109
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0077 0.0356
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.0524 1
Echinococcus granulosus hypothetical protein 0.0022 0.0109 0.0109
Echinococcus granulosus fmrfamide receptor 0.0022 0.0109 0.0109
Toxoplasma gondii endonuclease IV APN 0.0084 0.0646 1
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0033 0.0202 0.3008
Mycobacterium leprae PROBABLE GRPE PROTEIN (HSP-70 COFACTOR) 0.0034 0.0215 0.1956
Entamoeba histolytica hypothetical protein 0.004 0.026 0.8984
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.003 0.0174 0.016
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0022 0.0109 0.0109
Onchocerca volvulus 0.0022 0.0109 0.0392
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0022 0.0106 0.1509
Loa Loa (eye worm) hypothetical protein 0.0022 0.0109 0.0095
Brugia malayi hypothetical protein 0.0022 0.0109 0.0109
Echinococcus granulosus histone acetyltransferase KAT2B 0.0155 0.1256 0.1256
Schistosoma mansoni z-protein (S1r protein) 0.0021 0.01 0.01
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0018 0.0077 0.0077
Loa Loa (eye worm) hypothetical protein 0.0022 0.0109 0.0095
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0033 0.0202 0.0202
Echinococcus multilocularis neuropeptide Y receptor 0.0022 0.0109 0.0109
Loa Loa (eye worm) cysteine protease 0.0018 0.0077 0.0063
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.0524 1
Brugia malayi G-protein coupled receptor 0.0022 0.0109 0.0109
Echinococcus granulosus 7tm_1 domain containing protein 0.0022 0.0109 0.0109
Loa Loa (eye worm) hypothetical protein 0.0022 0.0109 0.0095
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0041 0.0269 0.4837
Schistosoma mansoni regulator of G protein signaling 0.0021 0.01 0.01
Echinococcus multilocularis indoleamine 2,3 dioxygenase 2 0.1169 1 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0018 0.0077 0.0356
Echinococcus granulosus 7TM GPCR rhodopsin 0.0022 0.0109 0.0109
Loa Loa (eye worm) RGS-3 protein 0.0021 0.01 0.0086
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0022 0.0109 0.0109
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0084 0.0646 1
Loa Loa (eye worm) ctsf protein 0.0018 0.0077 0.0063
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0022 0.0106 0.0092
Onchocerca volvulus 0.0022 0.0109 0.0392
Echinococcus multilocularis G protein coupled receptor 139 0.0525 0.4446 0.4446
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.0109 0.0109
Schistosoma mansoni serine/threonine protein kinase 0.0021 0.01 0.01
Onchocerca volvulus 0.0022 0.0109 0.0392
Echinococcus multilocularis fmrfamide receptor 0.0022 0.0109 0.0109
Echinococcus multilocularis orexin receptor type 2 0.0022 0.0109 0.0109
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0077 0.0356
Echinococcus multilocularis lamin 0.003 0.0174 0.0174
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0021 0.01 0.01
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.0109 0.0109
Loa Loa (eye worm) hypothetical protein 0.0022 0.0109 0.0095
Echinococcus multilocularis ubiquitin specific protease 41 0.0041 0.0269 0.0269
Loa Loa (eye worm) RecQ helicase 0.0022 0.0106 0.0092
Schistosoma mansoni opsin-like receptor 0.0022 0.0109 0.0109
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0041 0.0269 0.9231
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.0524 1
Loa Loa (eye worm) hypothetical protein 0.0022 0.0109 0.0095
Leishmania major cathepsin L-like protease 0.0018 0.0077 0.0941
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0033 0.0202 0.0202
Toxoplasma gondii exonuclease III APE 0.0021 0.0097 0.1358
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0022 0.0106 0.2029
Onchocerca volvulus 0.0022 0.0109 0.0392
Echinococcus granulosus g protein coupled receptor 0.0022 0.0109 0.0109
Schistosoma mansoni biogenic amine (5HT) receptor 0.0022 0.0109 0.0109
Brugia malayi larval opioid receptor 0.0022 0.0109 0.0109
Loa Loa (eye worm) hypothetical protein 0.003 0.0174 0.016
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.0524 1
Plasmodium falciparum GrpE protein homolog, mitochondrial, putative 0.0034 0.0215 0.332
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0021 0.01 0.01
Mycobacterium ulcerans hypothetical protein 0.0022 0.011 0.0233
Loa Loa (eye worm) hypothetical protein 0.0022 0.0109 0.0095
Onchocerca volvulus 0.0022 0.0109 0.0392
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.0109 0.0109
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.0524 1
Echinococcus multilocularis G-protein coupled receptor, putative 0.0022 0.0109 0.0109
Entamoeba histolytica cysteine protease, putative 0.0018 0.0077 0.2666
Loa Loa (eye worm) intermediate filament protein 0.003 0.0174 0.016
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0022 0.0106 0.0106
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0077 0.0356
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0041 0.0269 0.0269
Schistosoma mansoni hypothetical protein 0.004 0.026 0.026
Echinococcus multilocularis geminin 0.0187 0.1528 0.1528
Echinococcus multilocularis neuropeptide receptor 0.0525 0.4446 0.4446
Trypanosoma cruzi co-chaperone GrpE, putative 0.0034 0.0215 0.4094
Echinococcus granulosus regulator of G protein signaling 7 0.0021 0.01 0.01
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0064 0.0472 0.8997
Schistosoma mansoni adenoreceptor 0.0022 0.0109 0.0109
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0021 0.0097 0.0097
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0077 0.0356
Loa Loa (eye worm) TYRA-2 protein 0.0022 0.0109 0.0095
Onchocerca volvulus 0.0022 0.0109 0.0392
Schistosoma mansoni neuropeptide f receptor 76f 0.0022 0.0109 0.0109
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0022 0.0106 0.0106
Schistosoma mansoni transcription factor LCR-F1 0.004 0.026 0.026
Schistosoma mansoni hypothetical protein 0.0022 0.0109 0.0109
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.01 0.0462
Brugia malayi Dopamine receptor protein 1 0.0022 0.0109 0.0109
Brugia malayi ORL1-like opioid receptor 0.0022 0.0109 0.0109
Echinococcus granulosus histone lysine methyltransferase setb 0.0033 0.0202 0.0202
Onchocerca volvulus 0.0022 0.0109 0.0392
Brugia malayi GrpE protein homolog, mitochondrial precursor 0.0034 0.0215 0.0215
Trypanosoma cruzi cysteine peptidase, putative 0.007 0.0524 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0077 0.0356
Brugia malayi Intermediate filament tail domain containing protein 0.003 0.0174 0.0174
Schistosoma mansoni intermediate filament proteins 0.003 0.0174 0.0174
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0022 0.0109 0.0109
Trypanosoma cruzi cysteine peptidase, putative 0.007 0.0524 1
Trypanosoma cruzi major cysteine proteinase, putative 0.0055 0.0394 0.7525
Echinococcus multilocularis bloom syndrome protein 0.0022 0.0106 0.0106
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0021 0.01 0.0086
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0041 0.0269 0.514
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0021 0.0097 0.0097
Echinococcus granulosus rhodopsin orphan GPCR 0.0022 0.0109 0.0109
Schistosoma mansoni ap endonuclease 0.0021 0.0097 0.0097
Brugia malayi cytoplasmic intermediate filament protein 0.0016 0.0055 0.0055
Brugia malayi exodeoxyribonuclease III family protein 0.0021 0.0097 0.0097
Loa Loa (eye worm) hypothetical protein 0.0022 0.0109 0.0095
Brugia malayi neuropeptide F receptor 0.0022 0.0109 0.0109
Echinococcus multilocularis axis inhibition protein axin 0.0021 0.01 0.01
Trichomonas vaginalis DNA helicase recq, putative 0.0022 0.0106 0.049
Echinococcus granulosus neuropeptide receptor A26 0.0022 0.0109 0.0109
Echinococcus multilocularis regulator of G protein signaling 3 0.0021 0.01 0.01
Echinococcus multilocularis dro:myosuppressin receptor 0.0022 0.0109 0.0109
Schistosoma mansoni amine GPCR 0.0022 0.0109 0.0109
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.0109 0.0109
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0022 0.0109 0.0109
Loa Loa (eye worm) neuropeptide F receptor 0.0022 0.0109 0.0095
Schistosoma mansoni biogenic amine receptor 0.0022 0.0109 0.0109
Echinococcus granulosus cathepsin l1 0.0018 0.0077 0.0077
Brugia malayi hypothetical protein 0.0022 0.0109 0.0109
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0021 0.01 0.01
Schistosoma mansoni hypothetical protein 0.0022 0.0109 0.0109
Echinococcus multilocularis cathepsin L cysteine protease 0.0018 0.0077 0.0077
Onchocerca volvulus Neuropeptide F receptor homolog 0.0022 0.0109 0.0392
Echinococcus granulosus g protein coupled receptor 0.0022 0.0109 0.0109
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.0109 0.0109
Schistosoma mansoni DNA helicase recq1 0.0022 0.0106 0.0106
Schistosoma mansoni hypothetical protein 0.0022 0.0109 0.0109
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0018 0.0077 0.0356
Loa Loa (eye worm) hypothetical protein 0.0022 0.0109 0.0095
Echinococcus granulosus tm gpcr rhodopsin 0.0022 0.0109 0.0109
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0202 0.0202
Loa Loa (eye worm) hypothetical protein 0.0022 0.0109 0.0095
Toxoplasma gondii cathepsin CPL 0.0018 0.0077 0.105
Schistosoma mansoni amine GPCR 0.0022 0.0109 0.0109
Brugia malayi Cathepsin L-like precursor 0.0018 0.0077 0.0077
Echinococcus multilocularis g protein coupled receptor 0.0022 0.0109 0.0109
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0022 0.0109 0.0109
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0022 0.0109 0.0109
Loa Loa (eye worm) hypothetical protein 0.0021 0.01 0.0086
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0022 0.0109 0.0109
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0084 0.0646 1
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0084 0.0646 1
Loa Loa (eye worm) hypothetical protein 0.0014 0.0037 0.0023
Echinococcus granulosus tm gpcr rhodopsin 0.0022 0.0109 0.0109
Loa Loa (eye worm) G-protein coupled receptor 0.0022 0.0109 0.0095
Mycobacterium ulcerans sugar phosphate isomerases/epimerases 0.0022 0.011 0.0233
Echinococcus multilocularis regulator of G protein signaling 0.0021 0.01 0.01
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0077 0.0356
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0011 0.0014 0.0057
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0022 0.0109 0.0109
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.0109 0.0109
Echinococcus granulosus g-protein coupled receptor 0.0022 0.0109 0.0109
Onchocerca volvulus 0.003 0.0174 0.0698
Echinococcus multilocularis g-protein coupled receptor 0.0022 0.0109 0.0109
Trichomonas vaginalis grpe protein, putative 0.0034 0.0215 0.0989
Trichomonas vaginalis grpe protein, putative 0.0034 0.0215 0.0989
Echinococcus granulosus tachykinin peptides receptor 99D 0.0022 0.0109 0.0109
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0022 0.0106 0.2029
Schistosoma mansoni amine GPCR 0.0022 0.0109 0.0109
Brugia malayi GnHR receptor homolog 0.0022 0.0109 0.0109
Schistosoma mansoni neuropeptide receptor 0.0022 0.0109 0.0109
Schistosoma mansoni hypothetical protein 0.0022 0.0109 0.0109
Loa Loa (eye worm) hypothetical protein 0.0022 0.0109 0.0095
Echinococcus multilocularis somatostatin receptor 0.0022 0.0109 0.0109
Echinococcus multilocularis axis inhibition protein axin 0.0021 0.01 0.01
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0077 0.0356
Brugia malayi Cathepsin L-like precursor 0.0018 0.0077 0.0077
Echinococcus multilocularis beta adrenergic receptor kinase 0.0021 0.01 0.01
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0022 0.0109 0.0109
Schistosoma mansoni biogenic amine receptor 0.0022 0.0109 0.0109
Brugia malayi Serotonin receptor 0.0022 0.0109 0.0109
Onchocerca volvulus Putative hydroxypyruvate isomerase 0.0022 0.011 0.0397
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0077 0.0356
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.0109 0.0109
Brugia malayi follicle stimulating hormone receptor 0.0022 0.0109 0.0109
Echinococcus multilocularis lamin dm0 0.003 0.0174 0.0174
Entamoeba histolytica cysteine proteinase, putative 0.0012 0.0025 0.0848
Echinococcus granulosus expressed protein 0.0411 0.3464 0.3464
Brugia malayi Regulator of G protein signaling domain containing protein 0.0021 0.01 0.01
Leishmania major cathepsin L-like protease 0.0018 0.0077 0.0941
Echinococcus granulosus bloom syndrome protein 0.0022 0.0106 0.0106
Schistosoma mansoni neuropeptide F-like receptor 0.0022 0.0109 0.0109
Plasmodium vivax vivapain-2 0.0018 0.0077 0.1194
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0012 0.0025 0.0113
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.0524 1
Brugia malayi putative neuropeptide receptor 0.0022 0.0109 0.0109
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0022 0.0106 0.0106
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0022 0.0109 0.0109
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0022 0.0106 0.1646
Loa Loa (eye worm) hypothetical protein 0.0022 0.0109 0.0095
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0022 0.0109 0.0095
Loa Loa (eye worm) hypothetical protein 0.0022 0.0109 0.0095
Brugia malayi cathepsin L-like precursor 0.0012 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0022 0.0109 0.0095
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0022 0.0109 0.0109
Brugia malayi hypothetical protein 0.0021 0.01 0.01
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0022 0.0109 0.0109
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0011 0.0014 0.0217
Echinococcus multilocularis grpE protein 1, mitochondrial 0.0034 0.0215 0.0215
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0077 0.0356
Echinococcus granulosus cathepsin L cysteine proteinase 0.0018 0.0077 0.0077
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0014 0.0042 0.0042
Echinococcus granulosus geminin 0.0187 0.1528 0.1528
Loa Loa (eye worm) hypothetical protein 0.0022 0.0109 0.0095
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0077 0.0356
Brugia malayi PXA domain containing protein 0.0021 0.01 0.01
Loa Loa (eye worm) hypothetical protein 0.0022 0.0109 0.0095
Echinococcus granulosus ubiquitin specific protease 41 0.0041 0.0269 0.0269
Entamoeba histolytica hypothetical protein 0.0021 0.01 0.3463
Chlamydia trachomatis endonuclease IV 0.0084 0.0646 1
Loa Loa (eye worm) hypothetical protein 0.0022 0.0109 0.0095
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0022 0.0109 0.0109
Echinococcus granulosus rhodopsin orphan GPCR 0.0022 0.0109 0.0109
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0021 0.0097 0.1845
Loa Loa (eye worm) hypothetical protein 0.0022 0.0109 0.0095
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0041 0.0269 0.514
Echinococcus granulosus regulator of G protein signaling 7 0.0021 0.01 0.01
Loa Loa (eye worm) hypothetical protein 0.0014 0.0042 0.0028
Loa Loa (eye worm) hypothetical protein 0.0022 0.0109 0.0095
Loa Loa (eye worm) hypothetical protein 0.0022 0.0109 0.0095
Loa Loa (eye worm) hypothetical protein 0.0022 0.0109 0.0095
Brugia malayi hypothetical protein 0.0022 0.0109 0.0109
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0041 0.0269 0.514
Echinococcus multilocularis g protein coupled receptor 0.0022 0.0109 0.0109
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0022 0.0106 0.0106
Brugia malayi regulator of G-protein signaling rgs-7 0.0021 0.01 0.01
Trichomonas vaginalis bromodomain-containing protein, putative 0.0047 0.0323 0.1489
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0022 0.0109 0.0095
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0022 0.0109 0.0095
Onchocerca volvulus 0.0018 0.0077 0.0245
Loa Loa (eye worm) hypothetical protein 0.0022 0.0109 0.0095
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.0524 1
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0021 0.01 0.01
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0022 0.0109 0.0109
Echinococcus multilocularis cathepsin L cysteine protease 0.0018 0.0077 0.0077
Entamoeba histolytica recQ family helicase, putative 0.0011 0.001 0.0359
Schistosoma mansoni blooms syndrome DNA helicase 0.0011 0.001 0.001
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0022 0.0109 0.0392
Mycobacterium ulcerans epimerase 0.0022 0.011 0.0233
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.0109 0.0109
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0018 0.0077 0.0063
Schistosoma mansoni neuropeptide receptor 0.0525 0.4446 0.4446
Brugia malayi hypothetical protein 0.0022 0.0109 0.0109
Echinococcus granulosus biogenic amine 5HT receptor 0.0022 0.0109 0.0109
Onchocerca volvulus 0.0022 0.0109 0.0392
Plasmodium vivax vivapain-2 0.0018 0.0077 0.1194
Plasmodium vivax GrpE protein homolog, mitochondrial, putative 0.0034 0.0215 0.332
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0077 0.0356
Entamoeba histolytica recQ family helicase, putative 0.0022 0.0106 0.3676
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0022 0.0109 0.0109
Schistosoma mansoni blooms syndrome DNA helicase 0.0011 0.0014 0.0014
Echinococcus multilocularis fmrfamide receptor 0.0022 0.0109 0.0109
Echinococcus granulosus beta-adrenergic receptor kinase 0.0021 0.01 0.01
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0041 0.0269 0.0269
Giardia lamblia Histone acetyltransferase GCN5 0.0043 0.0289 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0022 0.0109 0.0109
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.01 0.0462
Echinococcus multilocularis cysteine protease 0.0018 0.0077 0.0077
Schistosoma mansoni lamin 0.003 0.0174 0.0174
Leishmania major cysteine peptidase A (CPA) 0.0018 0.0077 0.0941
Echinococcus multilocularis regulator of G protein signaling 7 0.0021 0.01 0.01
Loa Loa (eye worm) hypothetical protein 0.0029 0.017 0.0156
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.0109 0.0109
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.01 0.0462
Schistosoma mansoni grpe protein 0.0034 0.0215 0.0215
Entamoeba histolytica recQ family DNA helicase 0.0011 0.0014 0.0485
Plasmodium vivax SET domain protein, putative 0.0033 0.0202 0.312
Echinococcus granulosus histone acetyltransferase KAT2B 0.0047 0.0323 0.0323
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0047 0.0323 0.4916
Echinococcus granulosus somatostatin receptor 0.0022 0.0109 0.0109
Brugia malayi AKH receptor 0.0022 0.0109 0.0109
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0022 0.0109 0.0109
Loa Loa (eye worm) indoleamine 2,3-dioxygenase 0.1169 1 1
Mycobacterium ulcerans endonuclease IV 0.0084 0.0646 1
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0022 0.0109 0.0109
Entamoeba histolytica acetyltransferase, GNAT family 0.0043 0.0289 1
Echinococcus multilocularis allatostatin A receptor 0.0022 0.0109 0.0109
Trypanosoma cruzi cysteine peptidase, putative 0.007 0.0524 1
Leishmania major cathepsin L-like protease 0.007 0.0524 1
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0022 0.0109 0.0109
Schistosoma mansoni alpha-1 adrenergic receptor 0.0022 0.0109 0.0109
Onchocerca volvulus 0.0022 0.0109 0.0392
Schistosoma mansoni amine GPCR 0.0022 0.0109 0.0109
Onchocerca volvulus 0.0022 0.0109 0.0392
Brugia malayi sulfakinin receptor protein 0.0022 0.0109 0.0109
Entamoeba histolytica hypothetical protein 0.004 0.026 0.8984
Brugia malayi Cathepsin L-like precursor 0.0012 0.0025 0.0025
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0022 0.0109 0.0109
Onchocerca volvulus 0.0018 0.0077 0.0245
Treponema pallidum exodeoxyribonuclease (exoA) 0.0021 0.0097 0.4124
Mycobacterium ulcerans GrpE protein (Hsp-70 cofactor) 0.0034 0.0215 0.2144
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0077 0.0356
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0021 0.01 0.01
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0077 0.0356
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0021 0.0097 0.1338
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0021 0.01 0.01
Brugia malayi Regulator of G protein signaling domain containing protein 0.0021 0.01 0.01
Brugia malayi regulator of G-protein signaling egl-10 0.0021 0.01 0.01
Echinococcus granulosus sex peptide receptor 0.0022 0.0109 0.0109
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0022 0.0109 0.0109
Echinococcus multilocularis Regulator of G protein signaling 20 0.0021 0.01 0.01
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0022 0.0106 0.0106
Entamoeba histolytica hypothetical protein 0.0021 0.01 0.3463
Toxoplasma gondii co-chaperone GrpE protein 0.0034 0.0215 0.3211
Echinococcus multilocularis serotonin receptor 0.0022 0.0109 0.0109
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0041 0.0269 0.0269
Echinococcus granulosus rhodopsin orphan GPCR 0.0022 0.0109 0.0109
Schistosoma mansoni opsin-like receptor 0.0022 0.0109 0.0109
Echinococcus multilocularis expressed protein 0.0411 0.3464 0.3464
Loa Loa (eye worm) hypothetical protein 0.0021 0.01 0.0086
Loa Loa (eye worm) hypothetical protein 0.0022 0.0109 0.0095
Schistosoma mansoni serine/threonine protein kinase 0.0021 0.01 0.01
Loa Loa (eye worm) hypothetical protein 0.0012 0.0025 0.0011
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0022 0.0106 0.0106
Brugia malayi Cathepsin L-like cysteine proteinase 0.0012 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0022 0.0109 0.0095
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.01 0.0462
Echinococcus granulosus lamin 0.003 0.0174 0.0174
Onchocerca volvulus 0.0022 0.0109 0.0392
Loa Loa (eye worm) hypothetical protein 0.0022 0.0109 0.0095
Brugia malayi intermediate filament protein 0.003 0.0174 0.0174
Echinococcus granulosus regulator of G protein signaling 3 0.0021 0.01 0.01
Echinococcus granulosus grpE protein 1 mitochondrial 0.0034 0.0215 0.0215
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0077 0.0356
Loa Loa (eye worm) hypothetical protein 0.0014 0.0037 0.0023
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0022 0.0109 0.0109
Echinococcus granulosus serotonin receptor 0.0022 0.0109 0.0109
Echinococcus granulosus lamin dm0 0.003 0.0174 0.0174
Echinococcus granulosus cathepsin l cysteine peptidase 0.0018 0.0077 0.0077
Loa Loa (eye worm) hypothetical protein 0.0022 0.0109 0.0095
Schistosoma mansoni lamin 0.003 0.0174 0.0174
Echinococcus granulosus peptide allatostatin:somatostatin 0.0022 0.0109 0.0109
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0016 0.0055 0.0041
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.0109 0.0109
Echinococcus granulosus rhodopsin orphan GPCR 0.0022 0.0109 0.0109
Leishmania major cathepsin L-like protease 0.007 0.0524 1
Loa Loa (eye worm) hypothetical protein 0.0021 0.01 0.0086
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0022 0.0109 0.0109
Onchocerca volvulus 0.003 0.0174 0.0698
Loa Loa (eye worm) hypothetical protein 0.0022 0.0109 0.0095
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0021 0.0097 0.1497
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0077 0.0356
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.004 0.026 0.026
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.0109 0.0109
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.0524 1
Loa Loa (eye worm) hypothetical protein 0.0022 0.0109 0.0095
Trypanosoma cruzi co-chaperone GrpE, putative 0.0034 0.0215 0.4094
Schistosoma mansoni neuropeptide receptor 0.0022 0.0109 0.0109
Echinococcus multilocularis neuropeptides capa receptor 0.0022 0.0109 0.0109
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0021 0.0097 0.1497
Brugia malayi RE15519p 0.0022 0.0109 0.0109
Echinococcus granulosus Regulator of G protein signaling 20 0.0021 0.01 0.01
Loa Loa (eye worm) hypothetical protein 0.0012 0.0025 0.0011
Schistosoma mansoni regulator of G protein signaling 0.0021 0.01 0.01
Trichomonas vaginalis DNA helicase recq1, putative 0.0022 0.0106 0.049
Echinococcus granulosus neuropeptide FF receptor 2 0.0022 0.0109 0.0109
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0022 0.0109 0.0109
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.016 0.1295 0.1295
Loa Loa (eye worm) PXA domain-containing protein 0.0021 0.01 0.0086
Leishmania major co-chaperone GrpE, putative 0.0034 0.0215 0.3726
Loa Loa (eye worm) hypothetical protein 0.0011 0.0014 0.000000000077752
Onchocerca volvulus 0.0022 0.0109 0.0392
Loa Loa (eye worm) hypothetical protein 0.0022 0.011 0.0096
Echinococcus multilocularis neuropeptide s receptor 0.0022 0.0109 0.0109
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0022 0.0109 0.0109
Loa Loa (eye worm) hypothetical protein 0.0022 0.0109 0.0095
Loa Loa (eye worm) hypothetical protein 0.0022 0.0109 0.0095
Loa Loa (eye worm) hypothetical protein 0.0041 0.0269 0.0256
Schistosoma mansoni regulator of G protein signaling 0.0021 0.01 0.01
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.01 0.0462
Mycobacterium tuberculosis Conserved hypothetical protein 0.0022 0.011 0.0233
Echinococcus granulosus axis inhibition protein axin 0.0021 0.01 0.01
Trichomonas vaginalis ap endonuclease, putative 0.0021 0.0097 0.0446
Echinococcus granulosus biogenic amine 5HT receptor 0.0022 0.0109 0.0109
Echinococcus granulosus cathepsin l1 0.0012 0.0025 0.0025
Loa Loa (eye worm) melatonin receptor type 1A 0.0022 0.0109 0.0095
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0018 0.0077 0.0063
Onchocerca volvulus 0.0018 0.0077 0.0245
Echinococcus granulosus g protein coupled receptor 0.0022 0.0109 0.0109
Brugia malayi hypothetical protein 0.0022 0.0109 0.0109
Brugia malayi Bloom's syndrome protein homolog 0.0022 0.0106 0.0106
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0021 0.0097 0.3344
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.016 0.1295 0.1295
Trichomonas vaginalis ap endonuclease, putative 0.0021 0.0097 0.0446
Schistosoma mansoni opsin-like receptor 0.0022 0.0109 0.0109
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0014 0.0042 0.0042
Trichomonas vaginalis DNA helicase recq, putative 0.0022 0.0106 0.049
Loa Loa (eye worm) hypothetical protein 0.0022 0.0109 0.0095
Echinococcus granulosus neuropeptide s receptor 0.0022 0.0109 0.0109
Brugia malayi Dopamine receptor 0.0022 0.0109 0.0109
Loa Loa (eye worm) fibroinase 0.0018 0.0077 0.0063
Trypanosoma brucei co-chaperone GrpE, putative 0.0034 0.0215 0.4094
Loa Loa (eye worm) hypothetical protein 0.0022 0.0109 0.0095
Brugia malayi PXA domain containing protein 0.0021 0.01 0.01
Loa Loa (eye worm) hypothetical protein 0.0021 0.0102 0.0088
Echinococcus multilocularis sex peptide receptor 0.0022 0.0109 0.0109

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

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