Detailed information for compound 1482022

Basic information

Technical information
  • TDR Targets ID: 1482022
  • Name: N-cyclohexyl-2-[(5-phenyl-1,3,4-oxadiazol-2-y l)sulfanyl]acetamide
  • MW: 317.406 | Formula: C16H19N3O2S
  • H donors: 1 H acceptors: 3 LogP: 3.41 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(NC1CCCCC1)CSc1nnc(o1)c1ccccc1
  • InChi: 1S/C16H19N3O2S/c20-14(17-13-9-5-2-6-10-13)11-22-16-19-18-15(21-16)12-7-3-1-4-8-12/h1,3-4,7-8,13H,2,5-6,9-11H2,(H,17,20)
  • InChiKey: NNHSDQAGVMPNHV-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-cyclohexyl-2-[(5-phenyl-1,3,4-oxadiazol-2-yl)thio]acetamide
  • N-cyclohexyl-2-[(5-phenyl-1,3,4-oxadiazol-2-yl)sulfanyl]ethanamide
  • MLS000061967
  • SMR000070828
  • ZINC00073391
  • BAS 02534268
  • N-Cyclohexyl-2-(5-phenyl-[1,3,4]oxadiazol-2-ylsulfanyl)-acetamide

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens tumor protein p53 Starlite/ChEMBL No references
Homo sapiens isocitrate dehydrogenase 1 (NADP+), soluble Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Leishmania infantum isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Trypanosoma congolense isocitrate dehydrogenase, putative Get druggable targets OG5_127057 All targets in OG5_127057
Leishmania mexicana isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Neospora caninum hypothetical protein Get druggable targets OG5_127057 All targets in OG5_127057
Candida albicans N terminus of cytosolic NADP-specific isocitrate dehydrogenase. Get druggable targets OG5_127057 All targets in OG5_127057
Loa Loa (eye worm) isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Trypanosoma brucei gambiense isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus multilocularis tumor protein p63 Get druggable targets OG5_140038 All targets in OG5_140038
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative Get druggable targets OG5_127057 All targets in OG5_127057
Babesia bovis isocitrate dehydrogenase, NADP-dependent family protein Get druggable targets OG5_127057 All targets in OG5_127057
Theileria parva isocitrate dehydrogenase (NADP+), putative Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus multilocularis isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Plasmodium knowlesi isocitrate dehydrogenase [NADP], mitochondrial, putative Get druggable targets OG5_127057 All targets in OG5_127057
Plasmodium berghei isocitrate dehydrogenase [NADP], mitochondrial, putative Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus granulosus NADP dependent isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Trypanosoma congolense isocitrate dehydrogenase, putative Get druggable targets OG5_127057 All targets in OG5_127057
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus granulosus tumor protein p63 Get druggable targets OG5_140038 All targets in OG5_140038
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Candida albicans cytosolic NADP-specific isocitrate dehydrogenase. Get druggable targets OG5_127057 All targets in OG5_127057
Candida albicans Mitochondrial NADP-specific isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Plasmodium yoelii isocitrate dehydrogenase, NADP-dependent Get druggable targets OG5_127057 All targets in OG5_127057
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial Get druggable targets OG5_127057 All targets in OG5_127057
Leishmania donovani isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Brugia malayi isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Candida albicans C terminus of cytosolic NADP-specific isocitrate dehydrogenase. Get druggable targets OG5_127057 All targets in OG5_127057
Toxoplasma gondii isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Toxoplasma gondii isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Brugia malayi Isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Trypanosoma cruzi isocitrate dehydrogenase, putative Get druggable targets OG5_127057 All targets in OG5_127057
Candida albicans Mitochondrial NADP-specific isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Trypanosoma brucei isocitrate dehydrogenase, putative Get druggable targets OG5_127057 All targets in OG5_127057
Trypanosoma brucei gambiense isocitrate dehydrogenase, putative Get druggable targets OG5_127057 All targets in OG5_127057
Plasmodium yoelii isocitrate dehydrogenase, NADP-dependent, putative Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) Get druggable targets OG5_127057 All targets in OG5_127057
Schistosoma japonicum ko:K00031 isocitrate dehydrogenase [EC1.1.1.42], putative Get druggable targets OG5_127057 All targets in OG5_127057
Schistosoma mansoni NADP-specific isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) Get druggable targets OG5_127057 All targets in OG5_127057
Neospora caninum Isocitrate dehydrogenase-like protein, related Get druggable targets OG5_127057 All targets in OG5_127057
Leishmania braziliensis isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni transcription factor btf3 0.0034 0.0166 0.0207
Loa Loa (eye worm) hypothetical protein 0.0047 0.0316 0.062
Echinococcus granulosus serotonin receptor 0.005 0.0349 0.0454
Echinococcus granulosus neuropeptides capa receptor 0.005 0.0349 0.0454
Brugia malayi RE15519p 0.005 0.0349 0.0688
Leishmania major heat shock protein 83-1 0.0032 0.0139 0.1454
Loa Loa (eye worm) hypothetical protein 0.005 0.0349 0.0688
Loa Loa (eye worm) hypothetical protein 0.005 0.0349 0.0688
Loa Loa (eye worm) hypothetical protein 0.003 0.0117 0.0214
Echinococcus granulosus calcium dependent protein kinase 0.0061 0.047 0.0617
Schistosoma mansoni hypothetical protein 0.0164 0.1655 0.2217
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0066 0.0528 0.0416
Loa Loa (eye worm) hypothetical protein 0.006 0.0461 0.0916
Entamoeba histolytica hypothetical protein 0.0035 0.0178 0.0548
Echinococcus multilocularis heat shock protein 0.0032 0.0139 0.0144
Echinococcus multilocularis neuropeptide receptor A26 0.005 0.0349 0.0384
Schistosoma mansoni adenoreceptor 0.005 0.0349 0.0454
Brugia malayi Sugar transporter family protein 0.003 0.0117 0.0214
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0047 0.0316 0.2127
Echinococcus granulosus G protein coupled receptor 139 0.005 0.0349 0.0454
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0023 0.0042 0.0057
Onchocerca volvulus Poor gastrulation protein homolog 0.0035 0.0183 0.117
Schistosoma mansoni glucose transport protein 0.0211 0.2185 0.2932
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0066 0.0528 0.0635
Loa Loa (eye worm) neuropeptide F receptor 0.005 0.0349 0.0688
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0211 0.2185 0.2484
Trichomonas vaginalis sugar transport protein, putative 0.003 0.0117 0.039
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0063 0.0501 0.0659
Loa Loa (eye worm) hypothetical protein 0.005 0.0349 0.0688
Plasmodium falciparum calcium-dependent protein kinase 4 0.0066 0.0528 0.0528
Trichomonas vaginalis sugar transporter, putative 0.0065 0.0525 0.1742
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0047 0.0316 0.2607
Trichomonas vaginalis sugar transporter, putative 0.003 0.0117 0.039
Schistosoma mansoni lysyl-tRNA synthetase 0.0047 0.0316 0.0409
Echinococcus granulosus rhodopsin orphan GPCR 0.005 0.0349 0.0454
Schistosoma mansoni protein kinase 0.0066 0.0528 0.0695
Loa Loa (eye worm) hypothetical protein 0.005 0.0349 0.0688
Leishmania major heat shock protein 83-1 0.0032 0.0139 0.1454
Brugia malayi Endoplasmin precursor 0.0032 0.0139 0.0258
Toxoplasma gondii AGC kinase 0.0044 0.0283 0.0256
Loa Loa (eye worm) hypothetical protein 0.003 0.0117 0.0214
Trypanosoma brucei heat shock protein, putative 0.0032 0.0139 0.0284
Loa Loa (eye worm) hypothetical protein 0.005 0.0349 0.0688
Echinococcus granulosus tm gpcr rhodopsin 0.005 0.0349 0.0454
Loa Loa (eye worm) neuropeptide F receptor 0.005 0.0349 0.0688
Schistosoma mansoni neuropeptide f receptor 76f 0.005 0.0349 0.0454
Echinococcus multilocularis tachykinin peptides receptor 99D 0.005 0.0349 0.0384
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0066 0.0528 0.1053
Trichomonas vaginalis sugar transporter, putative 0.003 0.0117 0.039
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0074 0.062 0.66
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.0042 0.0095
Entamoeba histolytica transcription factor BTF3, putative 0.0034 0.0166 0.051
Echinococcus granulosus tm gpcr rhodopsin 0.005 0.0349 0.0454
Schistosoma mansoni biogenic amine receptor 0.005 0.0349 0.0454
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.005 0.0349 0.0688
Schistosoma mansoni protein kinase 0.0066 0.0528 0.0695
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0066 0.0528 0.0416
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.005 0.0349 0.0454
Echinococcus multilocularis neuropeptide Y receptor 0.005 0.0349 0.0384
Plasmodium falciparum heat shock protein 90 0.0032 0.0139 0.0139
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0096 0.088 0.117
Onchocerca volvulus 0.005 0.0349 0.2316
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0166 0.0552
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0074 0.062 0.7009
Plasmodium falciparum calcium-dependent protein kinase 3 0.0066 0.0528 0.0528
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0044 0.0283 0.3117
Trichomonas vaginalis sugar transporter, putative 0.003 0.0117 0.039
Trichomonas vaginalis CAMK family protein kinase 0.0096 0.088 0.2917
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.005 0.0349 0.0688
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0044 0.0283 0.0309
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0117 0.039
Onchocerca volvulus Metabotropic glutamate receptor homolog 0.0035 0.0183 0.117
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.0178 0.0222
Trichomonas vaginalis sugar transporter, putative 0.003 0.0117 0.039
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0166 0.0552
Trichomonas vaginalis sugar transporter, putative 0.003 0.0117 0.039
Trichomonas vaginalis sugar transporter, putative 0.003 0.0117 0.039
Loa Loa (eye worm) hypothetical protein 0.005 0.0349 0.0688
Schistosoma mansoni jumonji domain containing protein 0.0084 0.0741 0.0983
Loa Loa (eye worm) hypothetical protein 0.003 0.0117 0.0214
Trypanosoma brucei THT1 - hexose transporter, putative 0.0065 0.0525 0.535
Trypanosoma brucei glucose transporter 1E 0.0065 0.0525 0.535
Loa Loa (eye worm) hypothetical protein 0.005 0.0349 0.0688
Schistosoma mansoni rhodopsin-like orphan GPCR 0.005 0.0349 0.0454
Schistosoma mansoni rhodopsin-like orphan GPCR 0.005 0.0349 0.0454
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0063 0.0501 0.1625
Brugia malayi Bromodomain containing protein 0.0032 0.0149 0.0278
Onchocerca volvulus 0.005 0.0349 0.2316
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0044 0.0283 0.2174
Schistosoma mansoni heat shock protein 0.0032 0.0139 0.017
Schistosoma mansoni serine/threonine protein kinase 0.0044 0.0283 0.0365
Schistosoma mansoni biogenic amine receptor 0.005 0.0349 0.0454
Leishmania major hypothetical protein, conserved 0.003 0.0117 0.1204
Echinococcus multilocularis G protein coupled receptor 139 0.005 0.0349 0.0384
Echinococcus multilocularis jumonji domain containing protein 0.0045 0.0294 0.0321
Brugia malayi hypothetical protein 0.005 0.0349 0.0688
Brugia malayi hypothetical protein 0.005 0.0349 0.0688
Schistosoma mansoni glucose transport protein 0.0211 0.2185 0.2932
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0023 0.0042 0.0057
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.0042 0.0095
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.0056 0.0417 0.0826
Schistosoma mansoni hypothetical protein 0.005 0.0349 0.0454
Brugia malayi Tachykinin-like peptides receptor 99D 0.005 0.0349 0.0688
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.005 0.0349 0.0384
Brugia malayi follicle stimulating hormone receptor 0.005 0.0349 0.0688
Schistosoma mansoni hypothetical protein 0.005 0.0349 0.0454
Echinococcus granulosus neuropeptides capa receptor 0.005 0.0349 0.0454
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0211 0.2185 0.2932
Loa Loa (eye worm) hypothetical protein 0.005 0.0349 0.0688
Echinococcus multilocularis rho associated protein kinase 0.0148 0.1464 0.166
Brugia malayi Protein kinase domain containing protein 0.0449 0.49 1
Giardia lamblia Fructose-bisphosphate aldolase 0.0284 0.3015 1
Loa Loa (eye worm) G-protein coupled receptor 0.005 0.0349 0.0688
Leishmania major heat shock protein 83-1 0.0032 0.0139 0.1454
Schistosoma mansoni biogenic amine (5HT) receptor 0.005 0.0349 0.0454
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0064 0.051 0.0671
Giardia lamblia Lysyl-tRNA synthetase 0.0047 0.0316 0.0849
Trichomonas vaginalis sugar transporter, putative 0.003 0.0117 0.039
Echinococcus granulosus rhodopsin orphan GPCR 0.005 0.0349 0.0454
Echinococcus multilocularis serotonin receptor 0.005 0.0349 0.0384
Plasmodium falciparum basic transcription factor 3b, putative 0.0034 0.0166 0.0166
Echinococcus multilocularis g protein coupled receptor 0.005 0.0349 0.0384
Echinococcus multilocularis serotonin receptor 0.005 0.0349 0.0384
Echinococcus multilocularis survival motor neuron protein 1 0.0229 0.2397 0.2727
Echinococcus granulosus 7tm_1 domain containing protein 0.005 0.0349 0.0454
Brugia malayi hypothetical protein 0.005 0.0349 0.0688
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0342 0.3678 0.3603
Echinococcus multilocularis neuropeptide s receptor 0.005 0.0349 0.0384
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0035 0.0183 0.0348
Trichomonas vaginalis sugar transporter, putative 0.003 0.0117 0.039
Echinococcus granulosus solute carrier family 22 0.003 0.0117 0.0141
Trichomonas vaginalis CAMK family protein kinase 0.0096 0.088 0.2917
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.004 0.0235 0.1468
Echinococcus granulosus transcription factor Dp 1 0.0037 0.0202 0.0255
Echinococcus granulosus geminin 0.0164 0.1655 0.2217
Onchocerca volvulus 0.005 0.0349 0.2316
Echinococcus multilocularis rhodopsin orphan GPCR 0.005 0.0349 0.0384
Onchocerca volvulus 0.005 0.0349 0.2316
Echinococcus granulosus neuropeptide receptor 0.005 0.0349 0.0454
Plasmodium falciparum calcium-dependent protein kinase 1 0.0066 0.0528 0.0528
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0284 0.3015 1
Echinococcus multilocularis neuropeptide FF receptor 2 0.005 0.0349 0.0384
Trypanosoma brucei glucose transporter, putative 0.0065 0.0525 0.535
Trypanosoma brucei transcription factor BTF3, putative 0.0034 0.0166 0.0641
Echinococcus multilocularis orexin receptor type 2 0.005 0.0349 0.0384
Loa Loa (eye worm) hypothetical protein 0.005 0.0349 0.0688
Schistosoma mansoni sugar transporter 0.003 0.0117 0.0141
Brugia malayi Cam kinase protein 1 0.0066 0.0528 0.1053
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0032 0.0149 0.0184
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.005 0.0349 0.0454
Plasmodium falciparum mitogen-activated protein kinase 2 0.0342 0.3678 0.3678
Onchocerca volvulus 0.0148 0.1464 1
Brugia malayi Major Facilitator Superfamily protein 0.003 0.0117 0.0214
Echinococcus granulosus biogenic amine 5HT receptor 0.005 0.0349 0.0454
Echinococcus granulosus GPCR family 3 C terminal 0.0035 0.0183 0.0229
Echinococcus multilocularis transcription factor Dp 1 0.0037 0.0202 0.0216
Trypanosoma cruzi polo-like protein kinase, putative 0.0096 0.088 1
Loa Loa (eye worm) hypothetical protein 0.005 0.0349 0.0688
Trichomonas vaginalis glucose transporter, putative 0.0065 0.0525 0.1742
Echinococcus multilocularis sex peptide receptor 0.005 0.0349 0.0384
Loa Loa (eye worm) hypothetical protein 0.005 0.0349 0.0688
Trypanosoma brucei heat shock protein, putative 0.0032 0.0139 0.0284
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0066 0.0528 0.1053
Trichomonas vaginalis sugar transporter, putative 0.003 0.0117 0.039
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.0178 0.0188
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0074 0.062 0.7009
Brugia malayi PHD-finger family protein 0.0032 0.0149 0.0278
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.005 0.0349 0.2316
Brugia malayi hypothetical protein 0.005 0.0349 0.0688
Onchocerca volvulus 0.005 0.0349 0.2316
Echinococcus multilocularis rhodopsin orphan GPCR 0.005 0.0349 0.0384
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0284 0.3015 1
Trypanosoma cruzi glucose transporter, putative 0.003 0.0117 0.1204
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0284 0.3015 1
Brugia malayi neuropeptide F receptor 0.005 0.0349 0.0688
Trypanosoma brucei heat shock protein 90, putative 0.0032 0.0139 0.0284
Brugia malayi putative neuropeptide receptor NPR1 0.005 0.0349 0.0688
Trichomonas vaginalis CAMK family protein kinase 0.0096 0.088 0.2917
Brugia malayi G-protein coupled receptor 0.005 0.0349 0.0688
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0039 0.0225 0.0243
Onchocerca volvulus 0.005 0.0349 0.2316
Echinococcus multilocularis fmrfamide receptor 0.005 0.0349 0.0384
Loa Loa (eye worm) hypothetical protein 0.005 0.0349 0.0688
Brugia malayi Serotonin/octopamine receptor family protein 7 0.005 0.0349 0.0688
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0025 0.0066 0.0071
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0064 0.051 0.5735
Echinococcus multilocularis lysyl tRNA synthetase 0.0047 0.0316 0.0347
Schistosoma mansoni serine/threonine protein kinase 0.0044 0.0283 0.0365
Trichomonas vaginalis CAMK family protein kinase 0.0096 0.088 0.2917
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0106 0.099 0.1118
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0044 0.0283 0.0365
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0074 0.062 0.0777
Entamoeba histolytica heat shock protein 90, putative 0.0032 0.0139 0.042
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0117 0.039
Loa Loa (eye worm) hypothetical protein 0.005 0.0349 0.0688
Schistosoma mansoni opsin-like receptor 0.005 0.0349 0.0454
Leishmania major heat shock protein 83-1 0.0032 0.0139 0.1454
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.005 0.0349 0.0454
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.005 0.0349 0.0454
Loa Loa (eye worm) hypothetical protein 0.005 0.0349 0.0688
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0042 0.033
Echinococcus multilocularis g-protein coupled receptor 0.005 0.0349 0.0384
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.005 0.0349 0.0454
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0025 0.0066 0.0183
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0066 0.0528 0.0635
Trypanosoma cruzi Heat shock protein 83, putative 0.0032 0.0139 0.1454
Leishmania major glucose transporter, lmgt3 0.0065 0.0525 0.591
Loa Loa (eye worm) hypothetical protein 0.003 0.0117 0.0214
Plasmodium vivax CDK-related protein kinase 6, putative 0.0896 1 1
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0047 0.0316 0.2127
Brugia malayi hypothetical protein 0.005 0.0349 0.0688
Schistosoma mansoni neuropeptide receptor 0.005 0.0349 0.0454
Echinococcus granulosus rhodopsin orphan GPCR 0.005 0.0349 0.0454
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0342 0.3678 0.5503
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.005 0.0349 0.0688
Loa Loa (eye worm) hypothetical protein 0.0056 0.0417 0.0826
Toxoplasma gondii PHD-finger domain-containing protein 0.0032 0.0149 0.0049
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0284 0.3015 1
Echinococcus granulosus rhodopsin orphan GPCR 0.005 0.0349 0.0454
Echinococcus multilocularis rhodopsin orphan GPCR 0.005 0.0349 0.0384
Trichomonas vaginalis sugar transporter, putative 0.003 0.0117 0.039
Brugia malayi MH2 domain containing protein 0.0116 0.1101 0.2226
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.003 0.0117 0.0628
Trichomonas vaginalis sugar transporter, putative 0.003 0.0117 0.039
Onchocerca volvulus 0.003 0.0117 0.0719
Trichomonas vaginalis sugar transporter, putative 0.003 0.0117 0.039
Mycobacterium leprae Probable lysyl-tRNA synthase LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.004 0.0235 0.1468
Echinococcus granulosus sex peptide receptor 0.005 0.0349 0.0454
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0044 0.0283 0.0283
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0284 0.3015 1
Trypanosoma brucei heat shock protein, putative 0.0032 0.0139 0.0284
Echinococcus granulosus neuropeptide receptor A26 0.005 0.0349 0.0454
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0064 0.051 0.1017
Schistosoma mansoni opsin-like receptor 0.005 0.0349 0.0454
Echinococcus granulosus neuropeptide Y receptor 0.005 0.0349 0.0454
Trypanosoma brucei glucose transporter, putative 0.0065 0.0525 0.535
Schistosoma mansoni rhodopsin-like orphan GPCR 0.005 0.0349 0.0454
Echinococcus granulosus g protein coupled receptor 0.005 0.0349 0.0454
Echinococcus granulosus tachykinin peptides receptor 99D 0.005 0.0349 0.0454
Brugia malayi major facilitator superfamily protein 0.003 0.0117 0.0214
Schistosoma mansoni rhodopsin-like orphan GPCR 0.005 0.0349 0.0454
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0066 0.0528 0.1053
Echinococcus multilocularis biogenic amine (5HT) receptor 0.005 0.0349 0.0384
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0042 0.0059
Loa Loa (eye worm) major facilitator superfamily transporter 0.003 0.0117 0.0214
Brugia malayi Melatonin receptor type 1A 0.005 0.0349 0.0688
Echinococcus granulosus orexin receptor type 2 0.005 0.0349 0.0454
Mycobacterium tuberculosis Probable conserved integral membrane transport protein 0.003 0.0117 0.0575
Schistosoma mansoni sugar transporter 0.003 0.0117 0.0141
Echinococcus granulosus rhodopsin orphan GPCR 0.005 0.0349 0.0454
Plasmodium falciparum phd finger protein, putative 0.0032 0.0149 0.0149
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0064 0.051 0.0671
Schistosoma mansoni endoplasmin 0.0032 0.0139 0.017
Trichomonas vaginalis sugar transporter, putative 0.0065 0.0525 0.1742
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.005 0.0349 0.0454
Onchocerca volvulus 0.005 0.0349 0.2316
Toxoplasma gondii PHD-finger domain-containing protein 0.0032 0.0149 0.0049
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0023 0.0042 0.0057
Schistosoma mansoni neuropeptide receptor 0.005 0.0349 0.0454
Echinococcus multilocularis solute carrier family 22 0.003 0.0117 0.0119
Loa Loa (eye worm) hypothetical protein 0.003 0.0117 0.0214
Trichomonas vaginalis sugar transporter, putative 0.003 0.0117 0.039
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0096 0.088 1
Echinococcus multilocularis neuropeptide Y receptor 0.005 0.0349 0.0384
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0025 0.0066 0.0183
Trichomonas vaginalis sugar transporter, putative 0.003 0.0117 0.039
Echinococcus granulosus heat shock protein 90 0.0025 0.0066 0.0071
Schistosoma mansoni hypothetical protein 0.0035 0.0178 0.0222
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0064 0.051 0.5735
Loa Loa (eye worm) follicle stimulating hormone receptor 0.005 0.0349 0.0688
Trypanosoma brucei polo-like protein kinase 0.0096 0.088 1
Toxoplasma gondii heat shock protein HSP90 0.0032 0.0139 0.0033
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.003 0.0117 0.0117
Echinococcus granulosus tm gpcr rhodopsin 0.005 0.0349 0.0454
Schistosoma mansoni alpha-1 adrenergic receptor 0.005 0.0349 0.0454
Trypanosoma brucei THT1 - hexose transporter, putative 0.0065 0.0525 0.535
Echinococcus granulosus rho-associated protein kinase 1 0.0148 0.1464 0.196
Trypanosoma cruzi heat shock protein 90, putative 0.0032 0.0139 0.1454
Loa Loa (eye worm) hypothetical protein 0.0063 0.0501 0.0998
Onchocerca volvulus 0.005 0.0349 0.2316
Trypanosoma cruzi heat shock protein 85, putative 0.0032 0.0139 0.1454
Plasmodium falciparum calcium-dependent protein kinase 5 0.0066 0.0528 0.0528
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0063 0.0501 0.0558
Schistosoma mansoni glucose transport protein 0.0211 0.2185 0.2932
Trypanosoma cruzi hexose transporter, putative 0.0065 0.0525 0.591
Loa Loa (eye worm) heat shock protein 90 0.0032 0.0139 0.0258
Schistosoma mansoni serine/threonine protein kinase 0.0066 0.0528 0.0695
Brugia malayi hypothetical protein 0.005 0.0349 0.0688
Echinococcus multilocularis g protein coupled receptor 0.005 0.0349 0.0384
Trichomonas vaginalis myo-inositol transporter, putative 0.003 0.0117 0.039
Echinococcus granulosus g protein coupled receptor 0.005 0.0349 0.0454
Giardia lamblia Sugar-proton symporter 0.003 0.0117 0.0175
Echinococcus granulosus rhodopsin orphan GPCR 0.005 0.0349 0.0454
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0096 0.088 0.1773
Loa Loa (eye worm) hypothetical protein 0.005 0.0349 0.0688
Schistosoma mansoni microtubule-associated protein tau 0.067 0.7419 1
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0063 0.0501 0.0659
Loa Loa (eye worm) hypothetical protein 0.003 0.0117 0.0214
Plasmodium vivax hypothetical protein, conserved 0.0032 0.0149 0.0032
Trichomonas vaginalis sugar transporter, putative 0.003 0.0117 0.039
Trypanosoma cruzi hexose transporter, putative 0.0065 0.0525 0.591
Echinococcus granulosus tumor protein p63 0.0408 0.4435 0.5971
Leishmania major protein kinase, putative 0.0066 0.0528 0.594
Brugia malayi Receptor family ligand binding region containing protein 0.0056 0.0417 0.0826
Echinococcus multilocularis rhodopsin orphan GPCR 0.005 0.0349 0.0384
Echinococcus granulosus rhodopsin orphan GPCR 0.005 0.0349 0.0454
Leishmania major basic transcription factor 3a, putative 0.0034 0.0166 0.1768
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.0056 0.0417 0.0826
Schistosoma mansoni biogenic amine (dopamine) receptor 0.005 0.0349 0.0454
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.005 0.0349 0.0384
Brugia malayi neuropeptide F receptor 0.005 0.0349 0.0688
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0044 0.0283 0.0365
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.005 0.0349 0.0688
Echinococcus granulosus neuropeptide FF receptor 2 0.005 0.0349 0.0454
Schistosoma mansoni jumonji/arid domain-containing protein 0.0039 0.0227 0.0289
Leishmania major heat shock protein 83-1 0.0032 0.0139 0.1454
Trichomonas vaginalis sugar transporter, putative 0.003 0.0117 0.039
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0041 0.025 0.0829
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0042 0.0059
Leishmania major heat shock protein 83-1 0.0032 0.0139 0.1454
Onchocerca volvulus 0.003 0.0117 0.0719
Onchocerca volvulus 0.003 0.0117 0.0719
Onchocerca volvulus Neuropeptide F receptor homolog 0.005 0.0349 0.2316
Leishmania major myo-inositol/proton symporter (MIT) 0.003 0.0117 0.1204
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0139 0.136 1
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0023 0.0042 0.0057
Schistosoma mansoni hypothetical protein 0.005 0.0349 0.0454
Brugia malayi larval opioid receptor 0.005 0.0349 0.0688
Schistosoma mansoni rhodopsin-like orphan GPCR 0.005 0.0349 0.0454
Onchocerca volvulus 0.003 0.0117 0.0719
Brugia malayi hypothetical protein 0.0035 0.0178 0.0337
Entamoeba histolytica PH domain containing protein kinase, putative 0.0044 0.0283 0.09
Schistosoma mansoni survival motor neuron protein 0.0047 0.0313 0.0405
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0066 0.0528 0.0695
Loa Loa (eye worm) bifunctional aminoacyl-tRNA synthetase 0.0026 0.0075 0.0128
Trypanosoma cruzi polo-like protein kinase, putative 0.0096 0.088 1
Brugia malayi hypothetical protein 0.005 0.0349 0.0688
Brugia malayi hypothetical protein 0.003 0.0117 0.0214
Brugia malayi gonadotropin-releasing hormone receptor 2 0.005 0.0349 0.0688
Leishmania major heat shock protein 83-1 0.0032 0.0139 0.1454
Schistosoma mansoni hypothetical protein 0.0047 0.0313 0.0405
Leishmania major heat shock protein 83-1 0.0032 0.0139 0.1454
Trypanosoma brucei heat shock protein, putative 0.0032 0.0139 0.0284
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.005 0.0349 0.0384
Trichomonas vaginalis sugar transporter, putative 0.003 0.0117 0.039
Entamoeba histolytica hypothetical protein 0.0035 0.0178 0.0548
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.005 0.0349 0.0384
Schistosoma mansoni glucose transporter 0.003 0.0117 0.0141
Loa Loa (eye worm) G-protein coupled receptor 0.005 0.0349 0.0688
Toxoplasma gondii lysine-tRNA ligase 0.0047 0.0316 0.0307
Schistosoma mansoni neuropeptide receptor 0.005 0.0349 0.0454
Loa Loa (eye worm) hypothetical protein 0.005 0.0349 0.0688
Loa Loa (eye worm) MH2 domain-containing protein 0.0116 0.1101 0.2226
Echinococcus multilocularis solute carrier family 22 0.003 0.0117 0.0119
Onchocerca volvulus Putative transporter 0.003 0.0117 0.0719
Entamoeba histolytica hypothetical protein 0.0035 0.0178 0.0548
Loa Loa (eye worm) hypothetical protein 0.005 0.0349 0.0688
Schistosoma mansoni hypothetical protein 0.0032 0.0149 0.0184
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0066 0.0528 0.0589
Trichomonas vaginalis glucose transporter, putative 0.0065 0.0525 0.1742
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0044 0.0283 0.2174
Echinococcus multilocularis Sugar transporter ERD6 protein 0.003 0.0117 0.0119
Echinococcus multilocularis neuropeptide receptor 0.005 0.0349 0.0384
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0139 0.136 1
Echinococcus multilocularis microtubule associated protein 2 0.067 0.7419 0.847
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0211 0.2185 0.2484
Loa Loa (eye worm) melatonin receptor type 1A 0.005 0.0349 0.0688
Echinococcus granulosus lysine specific demethylase 5A 0.0039 0.0227 0.0289
Trichomonas vaginalis sugar transporter, putative 0.003 0.0117 0.039
Onchocerca volvulus 0.005 0.0349 0.2316
Trypanosoma cruzi hexose transporter 0.0065 0.0525 0.591
Echinococcus multilocularis rhodopsin orphan GPCR 0.005 0.0349 0.0384
Trypanosoma cruzi hexose transporter, putative 0.0065 0.0525 0.591
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0166 0.0552
Trypanosoma brucei Heat shock protein 83, putative 0.0032 0.0139 0.0284
Schistosoma mansoni growth hormone secretagogue receptor 0.005 0.0349 0.0454
Brugia malayi hypothetical protein 0.0229 0.2397 0.4879
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.005 0.0349 0.0384
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0066 0.0528 0.0589
Schistosoma mansoni amine GPCR 0.005 0.0349 0.0454
Loa Loa (eye worm) hypothetical protein 0.0044 0.0283 0.0553
Schistosoma mansoni sugar transporter 0.003 0.0117 0.0141
Echinococcus multilocularis General substrate transporter 0.0181 0.1846 0.2097
Onchocerca volvulus Alhambra homolog 0.0032 0.0149 0.0937
Plasmodium vivax hexose transporter 0.0211 0.2185 0.2092
Brugia malayi Metabotropic glutamate receptor precursor. 0.0218 0.2266 0.4611
Brugia malayi heat shock protein 90 0.0032 0.0139 0.0258
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0066 0.0528 0.0635
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0044 0.0283 0.3117
Echinococcus granulosus dro:myosuppressin receptor 0.005 0.0349 0.0454
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.005 0.0349 0.0454
Echinococcus granulosus Sugar transporter ERD6 protein 0.003 0.0117 0.0141
Trichomonas vaginalis sugar transporter, putative 0.003 0.0117 0.039
Trichomonas vaginalis CAMK family protein kinase 0.0066 0.0528 0.1751
Echinococcus multilocularis neuropeptides capa receptor 0.005 0.0349 0.0384
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0066 0.0528 0.0416
Loa Loa (eye worm) hypothetical protein 0.003 0.0117 0.0214
Loa Loa (eye worm) hypothetical protein 0.0147 0.1452 0.2945
Trichomonas vaginalis conserved hypothetical protein 0.0211 0.2185 0.7246
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0063 0.0501 0.0659
Echinococcus multilocularis neuropeptide receptor 0.005 0.0349 0.0384
Loa Loa (eye worm) hypothetical protein 0.005 0.0349 0.0688
Loa Loa (eye worm) hypothetical protein 0.005 0.0349 0.0688
Leishmania major heat shock protein 83-1 0.0032 0.0139 0.1454
Brugia malayi hypothetical protein 0.005 0.0349 0.0688
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0284 0.3015 1
Echinococcus multilocularis endoplasmin 0.0025 0.0066 0.006
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0211 0.2185 0.2484
Schistosoma mansoni rhodopsin-like orphan GPCR 0.005 0.0349 0.0454
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0106 0.099 0.132
Loa Loa (eye worm) hypothetical protein 0.005 0.0349 0.0688
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.0525 0.1742
Brugia malayi GnHR receptor homolog 0.005 0.0349 0.0688
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.0525 0.1742
Loa Loa (eye worm) hypothetical protein 0.005 0.0349 0.0688
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0047 0.0313 0.0614
Loa Loa (eye worm) hypothetical protein 0.005 0.0349 0.0688
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0064 0.051 0.1656
Onchocerca volvulus 0.003 0.0117 0.0719
Schistosoma mansoni hypothetical protein 0.0035 0.0183 0.0229
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0044 0.0283 0.0256
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0117 0.039
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0211 0.2185 0.2932
Onchocerca volvulus 0.003 0.0117 0.0719
Echinococcus granulosus neuropeptide s receptor 0.005 0.0349 0.0454
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0064 0.051 0.1017
Schistosoma mansoni metabotropic glutamate receptor 0.0183 0.1863 0.2497
Schistosoma mansoni biogenic amine (5HT) receptor 0.005 0.0349 0.0454
Loa Loa (eye worm) hypothetical protein 0.005 0.0349 0.0688
Echinococcus multilocularis synaptic vesicle 2 protein 0.003 0.0117 0.0119
Leishmania major protein kinase A catalytic subunit isoform 2 0.0044 0.0283 0.3117
Loa Loa (eye worm) hypothetical protein 0.003 0.0117 0.0214
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.005 0.0349 0.0384
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.003 0.0117 0.0141
Schistosoma mansoni biogenic amine receptor 0.005 0.0349 0.0454
Echinococcus granulosus biogenic amine 5HT receptor 0.005 0.0349 0.0454
Schistosoma mansoni endoplasmin 0.0032 0.0139 0.017
Entamoeba histolytica acyl-coA synthetase, putative 0.0023 0.0042 0.0095
Trypanosoma brucei heat shock protein, putative 0.0032 0.0139 0.0284
Loa Loa (eye worm) hypothetical protein 0.005 0.0349 0.0688
Trichomonas vaginalis sugar transporter, putative 0.003 0.0117 0.039
Loa Loa (eye worm) hypothetical protein 0.005 0.0349 0.0688
Trichomonas vaginalis sugar transporter, putative 0.003 0.0117 0.039
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.005 0.0349 0.0454
Onchocerca volvulus 0.003 0.0117 0.0719
Loa Loa (eye worm) major facilitator superfamily transporter 0.003 0.0117 0.0214
Echinococcus multilocularis g protein coupled receptor 0.005 0.0349 0.0384
Trypanosoma cruzi heat shock protein 85, putative 0.0032 0.0139 0.1454
Schistosoma mansoni jumonji/arid domain-containing protein 0.0039 0.0227 0.0289
Trypanosoma cruzi heat shock protein 85, putative 0.0025 0.0066 0.0608
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0064 0.051 0.5151
Loa Loa (eye worm) AGC/PKA protein kinase 0.0044 0.0283 0.0553
Loa Loa (eye worm) hypothetical protein 0.005 0.0349 0.0688
Trypanosoma cruzi heat shock protein 90, putative 0.0025 0.0066 0.0608
Echinococcus multilocularis rhodopsin orphan GPCR 0.005 0.0349 0.0384
Plasmodium falciparum proline--tRNA ligase 0.0074 0.062 0.062
Leishmania major heat shock protein 83-1 0.0032 0.0139 0.1454
Mycobacterium ulcerans hypothetical protein 0.0023 0.0042 0.0057
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.005 0.0349 0.0384
Schistosoma mansoni serine/threonine protein kinase 0.0044 0.0283 0.0365
Brugia malayi jmjC domain containing protein 0.0106 0.099 0.2
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0042 0.0059
Plasmodium falciparum lysine--tRNA ligase 0.0047 0.0316 0.0316
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0284 0.3015 1
Trichomonas vaginalis sugar transporter, putative 0.003 0.0117 0.039
Echinococcus multilocularis peregrin 0.0032 0.0149 0.0155
Leishmania major glucose transporter, lmgt2 0.0065 0.0525 0.591
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.005 0.0349 0.0688
Echinococcus granulosus somatostatin receptor 0.005 0.0349 0.0454
Loa Loa (eye worm) AGC/PKA protein kinase 0.0044 0.0283 0.0553
Echinococcus granulosus solute carrier family 22 0.003 0.0117 0.0141
Onchocerca volvulus 0.0047 0.0313 0.2068
Schistosoma mansoni cellular tumor antigen P53 0.006 0.0461 0.0604
Echinococcus multilocularis calcium dependent protein kinase 0.0061 0.047 0.0523
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0044 0.0283 0.0309
Trypanosoma cruzi heat shock protein 85, putative 0.0032 0.0139 0.1454
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0044 0.0283 0.0309
Echinococcus multilocularis somatostatin receptor 0.005 0.0349 0.0384
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.005 0.0349 0.0688
Loa Loa (eye worm) glutamate receptor 0.0086 0.0758 0.1524
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.005 0.0349 0.0384
Trypanosoma brucei glucose transporter 2A 0.0065 0.0525 0.535
Loa Loa (eye worm) hypothetical protein 0.005 0.0349 0.0688
Schistosoma mansoni serine/threonine protein kinase 0.0148 0.1464 0.196
Trichomonas vaginalis sugar transporter, putative 0.0065 0.0525 0.1742
Echinococcus granulosus 7TM GPCR rhodopsin 0.005 0.0349 0.0454
Loa Loa (eye worm) hypothetical protein 0.0056 0.0413 0.0819
Brugia malayi Dopamine receptor 0.005 0.0349 0.0688
Trichomonas vaginalis heat shock protein, putative 0.0025 0.0066 0.0218
Brugia malayi metabotropic glutamate receptor subtype 5a (mGluR5a), putative 0.0197 0.2032 0.4132
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0211 0.2185 0.2932
Schistosoma mansoni neuropeptide receptor 0.005 0.0349 0.0454
Trichomonas vaginalis sugar transporter, putative 0.003 0.0117 0.039
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0787 0.8756 1
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.0449 0.49 1
Loa Loa (eye worm) sugar transporter 0.0211 0.2185 0.4444
Loa Loa (eye worm) hypothetical protein 0.005 0.0349 0.0688
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0117 0.039
Brugia malayi AKH receptor 0.005 0.0349 0.0688
Schistosoma mansoni hypothetical protein 0.0211 0.2185 0.2932
Trichomonas vaginalis sugar transporter, putative 0.003 0.0117 0.039
Loa Loa (eye worm) hypothetical protein 0.005 0.0349 0.0688
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0063 0.0501 0.0998
Echinococcus granulosus g protein coupled receptor 0.005 0.0349 0.0454
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0047 0.0316 0.2082
Trypanosoma cruzi hexose transporter, putative 0.0036 0.0187 0.2007
Onchocerca volvulus 0.003 0.0117 0.0719
Plasmodium vivax calcium-dependent protein kinase, putative 0.0066 0.0528 0.0416
Mycobacterium tuberculosis Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter) 0.003 0.0117 0.0575
Trypanosoma cruzi hexose transporter, putative 0.003 0.0117 0.1204
Trypanosoma brucei heat shock protein, putative 0.0032 0.0139 0.0284
Trichomonas vaginalis sugar transporter, putative 0.003 0.0117 0.039
Brugia malayi lysyl-tRNA synthetase 0.0047 0.0316 0.062
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0074 0.062 0.7009
Echinococcus multilocularis geminin 0.0164 0.1655 0.1878
Schistosoma mansoni biogenic amine (dopamine) receptor 0.005 0.0349 0.0454
Trypanosoma brucei glucose transporter, putative 0.0065 0.0525 0.535
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.003 0.0117 0.0628
Schistosoma mansoni histamine h1 receptor 0.005 0.0349 0.0454
Trichomonas vaginalis AGC family protein kinase 0.0044 0.0283 0.0939
Schistosoma mansoni lysyl-tRNA synthetase 0.0047 0.0316 0.0409
Trichomonas vaginalis sugar transporter, putative 0.003 0.0117 0.039
Echinococcus multilocularis GPCR, family 3, C terminal 0.0035 0.0183 0.0194
Echinococcus granulosus jumonji domain containing protein 0.0045 0.0294 0.0379
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0066 0.0528 0.5384
Onchocerca volvulus 0.0147 0.1452 0.9915
Echinococcus granulosus peptide allatostatin:somatostatin 0.005 0.0349 0.0454
Loa Loa (eye worm) hypothetical protein 0.0063 0.0501 0.0998
Echinococcus granulosus fmrfamide receptor 0.005 0.0349 0.0454
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0044 0.0283 0.0553
Loa Loa (eye worm) transcription factor SMAD2 0.0116 0.1101 0.2226
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0044 0.0283 0.3117
Trichomonas vaginalis glucose transporter, putative 0.003 0.0117 0.039
Trypanosoma brucei glucose transporter, putative 0.0065 0.0525 0.535
Loa Loa (eye worm) hypothetical protein 0.005 0.0349 0.0688
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0139 0.136 1
Schistosoma mansoni amine GPCR 0.005 0.0349 0.0454
Entamoeba histolytica hypothetical protein 0.0034 0.0166 0.051
Schistosoma mansoni amine GPCR 0.005 0.0349 0.0454
Schistosoma mansoni rhodopsin-like orphan GPCR 0.005 0.0349 0.0454
Leishmania major protein kinase A catalytic subunit 0.0044 0.0283 0.3117
Schistosoma mansoni rhodopsin-like orphan GPCR 0.005 0.0349 0.0454
Loa Loa (eye worm) endoplasmin 0.0032 0.0139 0.0258
Leishmania major heat shock protein 83-1 0.0032 0.0139 0.1454
Toxoplasma gondii protein kinase, putative 0.0597 0.6587 1
Toxoplasma gondii facilitative glucose transporter GT1 0.0211 0.2185 0.3195
Loa Loa (eye worm) hypothetical protein 0.003 0.0117 0.0214
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0044 0.0283 0.2174
Echinococcus multilocularis dro:myosuppressin receptor 0.005 0.0349 0.0384
Giardia lamblia PHD finger protein 15 0.0032 0.0149 0.0282
Onchocerca volvulus 0.003 0.0117 0.0719
Onchocerca volvulus 0.003 0.0117 0.0719
Loa Loa (eye worm) hypothetical protein 0.003 0.0117 0.0214
Echinococcus granulosus endoplasmin 0.0025 0.0066 0.0071
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.005 0.0349 0.0454
Loa Loa (eye worm) hypothetical protein 0.005 0.0349 0.0688
Loa Loa (eye worm) hypothetical protein 0.005 0.0349 0.0688
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0064 0.051 0.0568
Echinococcus multilocularis solute carrier family 22 0.003 0.0117 0.0119
Loa Loa (eye worm) hypothetical protein 0.005 0.0349 0.0688
Echinococcus granulosus PHD finger protein rhinoceros 0.0032 0.0149 0.0184
Plasmodium vivax basic transcription factor 3b, putative 0.0034 0.0166 0.0049
Loa Loa (eye worm) hypothetical protein 0.005 0.0349 0.0688
Loa Loa (eye worm) hypothetical protein 0.005 0.0349 0.0688
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0042 0.0057
Plasmodium falciparum hexose transporter 0.0211 0.2185 0.2185
Trypanosoma brucei glucose transporter, putative 0.0065 0.0525 0.535
Entamoeba histolytica protein kinase, putative 0.0066 0.0528 0.1715
Echinococcus granulosus thyrotropin releasing hormone receptor 0.005 0.0349 0.0454
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.005 0.0349 0.0454
Brugia malayi hypothetical protein 0.0147 0.1452 0.2945
Treponema pallidum fructose-bisphosphate aldolase 0.0284 0.3015 1
Brugia malayi G protein-coupled receptor F59B2.13 0.005 0.0349 0.0688
Echinococcus multilocularis heat shock protein 90 0.0032 0.0139 0.0144
Trichomonas vaginalis CAMK family protein kinase 0.0096 0.088 0.2917
Loa Loa (eye worm) hypothetical protein 0.0229 0.2397 0.4879
Loa Loa (eye worm) hypothetical protein 0.005 0.0349 0.0688
Schistosoma mansoni neuropeptide F-like receptor 0.005 0.0349 0.0454
Loa Loa (eye worm) hypothetical protein 0.005 0.0349 0.0688
Schistosoma mansoni protein kinase 0.0066 0.0528 0.0695
Schistosoma mansoni hypothetical protein 0.0164 0.1655 0.2217
Echinococcus granulosus survival motor neuron protein 1 0.0229 0.2397 0.3219
Schistosoma mansoni myosin xvIII 0.005 0.0349 0.0454
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0066 0.0528 0.0589
Plasmodium vivax heat shock protein 86, putative 0.0032 0.0139 0.0022
Schistosoma mansoni rhodopsin-like orphan GPCR 0.005 0.0349 0.0454
Echinococcus granulosus neuropeptide receptor 0.005 0.0349 0.0454
Loa Loa (eye worm) sugar transporter 0.003 0.0117 0.0214
Entamoeba histolytica serine/threonine protein kinase, putative 0.0096 0.088 0.2887
Onchocerca volvulus 0.005 0.0349 0.2316
Leishmania major heat shock protein 83-1 0.0032 0.0139 0.1454
Brugia malayi hypothetical protein 0.003 0.0117 0.0214
Trichomonas vaginalis CAMK family protein kinase 0.0096 0.088 0.2917
Toxoplasma gondii NAC domain-containing protein 0.0034 0.0166 0.0076
Loa Loa (eye worm) hypothetical protein 0.0023 0.0042 0.0059
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0042 0.033
Loa Loa (eye worm) hypothetical protein 0.0032 0.0149 0.0278
Trichomonas vaginalis sugar transporter, putative 0.003 0.0117 0.039
Onchocerca volvulus 0.003 0.0117 0.0719
Schistosoma mansoni kinase 0.0051 0.0365 0.0476
Trichomonas vaginalis CAMK family protein kinase 0.005 0.0352 0.1166
Echinococcus multilocularis tumor protein p63 0.0408 0.4435 0.5057
Echinococcus multilocularis solute carrier family 22 0.003 0.0117 0.0119
Onchocerca volvulus 0.005 0.0349 0.2316
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.0178 0.0222
Plasmodium vivax proline--tRNA ligase, putative 0.0074 0.062 0.0509
Echinococcus granulosus solute carrier family 22 0.003 0.0117 0.0141
Trichomonas vaginalis sugar transporter, putative 0.003 0.0117 0.039
Echinococcus granulosus lysyl tRNA synthetase 0.0047 0.0316 0.0409
Plasmodium vivax lysine--tRNA ligase, putative 0.0047 0.0316 0.0201
Onchocerca volvulus 0.005 0.0349 0.2316
Leishmania major heat shock protein 83-1 0.0032 0.0139 0.1454
Loa Loa (eye worm) ICD-1 protein 0.0034 0.0166 0.0314
Loa Loa (eye worm) hypothetical protein 0.0051 0.0366 0.0721
Loa Loa (eye worm) hypothetical protein 0.0268 0.2841 0.5787
Loa Loa (eye worm) hypothetical protein 0.0023 0.0042 0.0059
Loa Loa (eye worm) hypothetical protein 0.005 0.0349 0.0688
Onchocerca volvulus 0.003 0.0117 0.0719
Loa Loa (eye worm) hypothetical protein 0.005 0.0349 0.0688
Chlamydia trachomatis lysine--tRNA ligase 0.0047 0.0316 1
Onchocerca volvulus 0.005 0.0349 0.2316
Echinococcus granulosus metabotropic glutamate receptor 2 0.0183 0.1863 0.2497
Brugia malayi Major Facilitator Superfamily protein 0.003 0.0117 0.0214
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0047 0.0316 0.3497
Leishmania major heat shock protein 83-1 0.0032 0.0139 0.1454
Brugia malayi ORL1-like opioid receptor 0.005 0.0349 0.0688
Echinococcus granulosus g-protein coupled receptor 0.005 0.0349 0.0454
Onchocerca volvulus 0.005 0.0349 0.2316
Echinococcus granulosus transcription factor btf3 0.0034 0.0166 0.0207
Echinococcus multilocularis metabotropic glutamate receptor 2 0.0183 0.1863 0.2115
Trichomonas vaginalis CAMK family protein kinase 0.0096 0.088 0.2917
Schistosoma mansoni metabotropic glutamate receptor 0.0106 0.0991 0.1321
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0042 0.033
Echinococcus granulosus peregrin 0.0032 0.0149 0.0184
Trichomonas vaginalis heat shock protein, putative 0.0025 0.0066 0.0218
Echinococcus granulosus allatostatin A receptor 0.005 0.0349 0.0454
Echinococcus granulosus neuropeptide Y receptor 0.005 0.0349 0.0454
Treponema pallidum heat shock protein 90 0.0025 0.0066 0.0106
Trypanosoma brucei glucose transporter, putative 0.0065 0.0525 0.535
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.004 0.0235 0.1468
Trichomonas vaginalis sugar transporter, putative 0.003 0.0117 0.039
Echinococcus granulosus hypothetical protein 0.005 0.0349 0.0454
Onchocerca volvulus 0.006 0.0461 0.3084
Echinococcus granulosus heat shock protein 0.0032 0.0139 0.017
Trypanosoma brucei THT1 - hexose transporter, putative 0.0065 0.0525 0.535
Brugia malayi Dopamine receptor protein 2 0.005 0.0349 0.0688
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.005 0.0349 0.0384
Loa Loa (eye worm) hypothetical protein 0.003 0.0117 0.0214
Brugia malayi G-protein coupled receptor 0.005 0.0349 0.0688
Entamoeba histolytica PH domain containing protein kinase, putative 0.0044 0.0283 0.09
Schistosoma mansoni biogenic amine (dopamine) receptor 0.005 0.0349 0.0454
Plasmodium falciparum protein kinase 7 0.0597 0.6587 0.6587
Trichomonas vaginalis sugar transporter, putative 0.003 0.0117 0.039
Schistosoma mansoni amine GPCR 0.005 0.0349 0.0454
Echinococcus multilocularis G-protein coupled receptor, putative 0.005 0.0349 0.0384
Echinococcus granulosus synaptic vesicle 2 protein 0.003 0.0117 0.0141
Giardia lamblia Prolyl-tRNA synthetase 0.0063 0.0501 0.1475
Onchocerca volvulus Serine\/threonine kinase homolog 0.0096 0.088 0.597
Toxoplasma gondii heat shock protein 90, putative 0.0032 0.0139 0.0033
Echinococcus granulosus metabotropic glutamate receptor 5 0.0268 0.2841 0.3818
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.005 0.0349 0.0384
Loa Loa (eye worm) hypothetical protein 0.005 0.0349 0.0688
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.005 0.0349 0.0454
Brugia malayi metabotropic glutamate receptor type 2 0.0106 0.0991 0.2002
Loa Loa (eye worm) hypothetical protein 0.0066 0.0528 0.1053
Giardia lamblia Hexose transporter 0.003 0.0117 0.0175
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0268 0.2841 0.3234
Trichomonas vaginalis heat shock protein, putative 0.0032 0.0139 0.0461
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0044 0.0283 0.0365
Giardia lamblia Heat shock protein HSP 90-alpha 0.0032 0.0139 0.0248
Onchocerca volvulus 0.003 0.0117 0.0719
Onchocerca volvulus 0.003 0.0117 0.0719
Echinococcus multilocularis rhodopsin orphan GPCR 0.005 0.0349 0.0384
Echinococcus multilocularis PHD finger protein rhinoceros 0.0032 0.0149 0.0155
Brugia malayi serine/threonine-protein kinase plk-2 0.0096 0.088 0.1773
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0074 0.062 0.7009
Brugia malayi hypothetical protein 0.003 0.0117 0.0214
Schistosoma mansoni serine/threonine protein kinase 0.0096 0.088 0.117
Loa Loa (eye worm) jmjC domain-containing protein 0.0067 0.0543 0.1084
Loa Loa (eye worm) TYRA-2 protein 0.005 0.0349 0.0688
Onchocerca volvulus 0.005 0.0349 0.2316
Loa Loa (eye worm) jmjC domain-containing protein 0.0039 0.0227 0.0437
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0063 0.0501 0.3483
Brugia malayi putative neuropeptide receptor 0.005 0.0349 0.0688
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0044 0.0283 0.0168
Echinococcus granulosus solute carrier family 22 0.003 0.0117 0.0141
Plasmodium falciparum calcium-dependent protein kinase 2 0.0066 0.0528 0.0528
Schistosoma mansoni peptide (allatostatin)-like receptor 0.005 0.0349 0.0454
Schistosoma mansoni hypothetical protein 0.005 0.0349 0.0454
Loa Loa (eye worm) hypothetical protein 0.005 0.0349 0.0688
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0117 0.039
Echinococcus multilocularis lysine specific demethylase 5A 0.0039 0.0227 0.0244
Echinococcus granulosus General substrate transporter 0.0181 0.1846 0.2475
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0042 0.0057
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0211 0.2185 0.2484
Mycobacterium ulcerans heat shock protein 90 0.0025 0.0066 0.0239
Onchocerca volvulus 0.003 0.0117 0.0719
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.005 0.0349 0.0384
Echinococcus multilocularis neuropeptides capa receptor 0.005 0.0349 0.0384
Brugia malayi Serotonin receptor 0.005 0.0349 0.0688
Schistosoma mansoni amine GPCR 0.005 0.0349 0.0454
Leishmania major heat shock protein 83-1 0.0032 0.0139 0.1454
Entamoeba histolytica protein kinase, putative 0.0066 0.0528 0.1715
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0063 0.0501 0.1661
Brugia malayi sulfakinin receptor protein 0.005 0.0349 0.0688
Onchocerca volvulus 0.003 0.0117 0.0719
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.003 0.0117 1
Loa Loa (eye worm) hypothetical protein 0.003 0.0117 0.0214
Loa Loa (eye worm) hypothetical protein 0.003 0.0117 0.0214
Schistosoma mansoni metabotropic glutamate receptor 2 3 (mglur group 2) 0.0248 0.2607 0.3503
Onchocerca volvulus 0.0143 0.1406 0.96
Loa Loa (eye worm) hypothetical protein 0.005 0.0349 0.0688
Echinococcus multilocularis transcription factor btf3 0.0034 0.0166 0.0175
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0284 0.3015 1
Trypanosoma brucei glucose transporter, putative 0.0065 0.0525 0.535
Loa Loa (eye worm) hypothetical protein 0.005 0.0349 0.0688
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0044 0.0283 0.3117
Entamoeba histolytica hypothetical protein 0.0035 0.0178 0.0548
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0064 0.051 0.5735
Leishmania major heat shock protein 83-1 0.0032 0.0139 0.1454
Trypanosoma brucei glucose transporter, putative 0.0065 0.0525 0.535
Echinococcus multilocularis rhodopsin orphan GPCR 0.005 0.0349 0.0384
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0066 0.0528 0.0589
Schistosoma mansoni opsin-like receptor 0.005 0.0349 0.0454
Loa Loa (eye worm) PHD-finger family protein 0.0032 0.0149 0.0278
Trichomonas vaginalis sugar transporter, putative 0.003 0.0117 0.039
Trypanosoma cruzi transcription factor btf3, putative 0.0034 0.0166 0.1768
Loa Loa (eye worm) hypothetical protein 0.003 0.0117 0.0214
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0284 0.3015 1
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0066 0.0528 0.0695
Echinococcus multilocularis heat shock protein 90 0.0025 0.0066 0.006
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.005 0.0349 0.0454
Onchocerca volvulus 0.005 0.0349 0.2316
Trichomonas vaginalis sugar transporter, putative 0.003 0.0117 0.039
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0044 0.0283 0.0309
Leishmania major heat shock protein 83-1 0.0032 0.0139 0.1454
Entamoeba histolytica heat shock protein 90, putative 0.0032 0.0139 0.042
Trichomonas vaginalis sugar transporter, putative 0.003 0.0117 0.039
Loa Loa (eye worm) hypothetical protein 0.005 0.0349 0.0688
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0039 0.0225 0.0286
Brugia malayi hypothetical protein 0.005 0.0349 0.0688
Trypanosoma cruzi sugar transporter, putative 0.003 0.0117 0.1204
Mycobacterium ulcerans sugar transporter 0.003 0.0117 0.0628
Leishmania major glucose transporter, lmgt1 0.0065 0.0525 0.591
Echinococcus multilocularis fmrfamide receptor 0.005 0.0349 0.0384
Schistosoma mansoni sugar transporter 0.003 0.0117 0.0141
Entamoeba histolytica hypothetical protein 0.0047 0.0316 0.101
Brugia malayi Major Facilitator Superfamily protein 0.003 0.0117 0.0214
Trypanosoma brucei heat shock protein, putative 0.0032 0.0139 0.0284
Loa Loa (eye worm) hypothetical protein 0.0035 0.0183 0.0348
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.005 0.0349 0.0454
Leishmania major protein kinase A catalytic subunit isoform 1 0.0044 0.0283 0.3117
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0211 0.2185 0.2932
Trypanosoma cruzi transcription factor btf3, putative 0.0034 0.0166 0.1768
Trichomonas vaginalis sugar transporter, putative 0.003 0.0117 0.039
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0063 0.0501 0.0998
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.005 0.0349 0.0454
Loa Loa (eye worm) hypothetical protein 0.005 0.0349 0.0688
Brugia malayi major facilitator superfamily protein 0.003 0.0117 0.0214
Echinococcus granulosus microtubule associated protein 2 0.067 0.7419 1
Brugia malayi Sugar transporter family protein 0.003 0.0117 0.0214
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0042 0.0057
Echinococcus granulosus alpha 1A adrenergic receptor 0.005 0.0349 0.0454
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0284 0.3015 1
Leishmania major glucose transporter/membrane transporter D2, putative 0.0065 0.0525 0.591
Brugia malayi Dopamine receptor protein 1 0.005 0.0349 0.0688
Trypanosoma brucei heat shock protein 90, putative 0.0032 0.0139 0.0284
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0047 0.0316 0.1049
Schistosoma mansoni neuropeptide F-like receptor 0.005 0.0349 0.0454
Echinococcus multilocularis alpha 1A adrenergic receptor 0.005 0.0349 0.0384
Trypanosoma brucei heat shock protein, putative 0.0032 0.0139 0.0284
Schistosoma mansoni heat shock protein 0.0032 0.0139 0.017
Brugia malayi beta-NAC-like protein 0.0034 0.0166 0.0314
Echinococcus granulosus heat shock protein 90 0.0032 0.0139 0.017
Brugia malayi G protein-coupled receptor 0.005 0.0349 0.0688
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0096 0.088 0.0991
Brugia malayi Sugar transporter family protein 0.0211 0.2185 0.4444
Loa Loa (eye worm) hypothetical protein 0.0023 0.0042 0.0059
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.005 0.0349 0.0688
Mycobacterium ulcerans integral membrane transport protein 0.003 0.0117 0.0628
Onchocerca volvulus 0.0023 0.0042 0.0197
Giardia lamblia Kinase, AGC PKA 0.0044 0.0283 0.0737
Plasmodium vivax endoplasmin, putative 0.0032 0.0139 0.0022
Loa Loa (eye worm) hypothetical protein 0.003 0.0117 0.0214
Onchocerca volvulus 0.005 0.0349 0.2316
Giardia lamblia Kinase, PLK 0.0096 0.088 0.2759
Echinococcus multilocularis allatostatin A receptor 0.005 0.0349 0.0384
Trichomonas vaginalis heat shock protein, putative 0.0025 0.0066 0.0218
Brugia malayi jmjC domain containing protein 0.0039 0.0227 0.0437
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0066 0.0528 0.0695
Brugia malayi Serotonin receptor 0.005 0.0349 0.0688
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0025 0.0066 0.0608
Brugia malayi hypothetical protein 0.005 0.0349 0.0688
Leishmania major lysyl-tRNA synthetase, putative 0.0047 0.0316 0.3497
Loa Loa (eye worm) glutamate receptor 0.0218 0.2266 0.4611
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0066 0.0528 0.0695
Trichomonas vaginalis sugar transporter, putative 0.003 0.0117 0.039
Trichomonas vaginalis CAMK family protein kinase 0.005 0.0352 0.1166
Toxoplasma gondii AGC kinase 0.0044 0.0283 0.0256

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 0.6513 uM PubChem BioAssay. qHTS for induction of synthetic lethality in tumor cells producing 2HG: qHTS for the HT-1080-NT fibrosarcoma cell line. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 10 uM PUBCHEM_BIOASSAY: qHTS assay for re-activators of p53 using a Luc reporter. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504709] ChEMBL. No reference
Potency (functional) 112.2018 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Iota. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588623] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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