Detailed information for compound 173170

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 676.764 | Formula: C30H48N10O8
  • H donors: 10 H acceptors: 8 LogP: -2.98 Rotable bonds: 26
    Rule of 5 violations (Lipinski): 3
  • SMILES: OC[C@@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N)CCC(=O)N)C(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)C)CCCN=C(N)N
  • InChi: 1S/C30H48N10O8/c1-16(2)24(29(48)37-19(25(32)44)11-12-23(31)43)40-28(47)22(15-41)39-26(45)20(10-7-13-35-30(33)34)38-27(46)21(36-17(3)42)14-18-8-5-4-6-9-18/h4-6,8-9,16,19-22,24,41H,7,10-15H2,1-3H3,(H2,31,43)(H2,32,44)(H,36,42)(H,37,48)(H,38,46)(H,39,45)(H,40,47)(H4,33,34,35)/t19-,20-,21-,22-,24-/m0/s1
  • InChiKey: DXABQJRMDPXFMC-YGQNSOCVSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus tyrosine kinase 0.1081 0.4992 0.4992
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0635 0.2913 0.2913
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0035 0.0116 0.0116
Echinococcus multilocularis Smad4 0.0016 0.0029 0.0029
Trypanosoma brucei Flagellum attachment zone protein 20 0.0446 0.2031 0.9993
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0635 0.2913 0.2913
Onchocerca volvulus 0.1081 0.4992 1
Entamoeba histolytica tyrosine kinase, putative 0.0446 0.2031 0.3926
Giardia lamblia GTOR 0.0046 0.0169 0.0058
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0635 0.2913 0.2913
Brugia malayi hypothetical protein 0.0446 0.2031 0.4068
Loa Loa (eye worm) hypothetical protein 0.0037 0.0125 0.0251
Plasmodium falciparum tyrosine kinase-like protein 0.0446 0.2031 0.9992
Echinococcus granulosus mothers against decapentaplegic 5 0.0016 0.0029 0.0029
Brugia malayi follicle stimulating hormone receptor 0.0271 0.1217 0.2438
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0124 0.0532 0.4353
Trichomonas vaginalis PIKK family atypical protein kinase 0.0046 0.0169 0.0785
Trichomonas vaginalis TKL family protein kinase 0.0446 0.2031 1
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0084 0.0345 0.1208
Entamoeba histolytica tyrosine kinase, putative 0.0446 0.2031 0.3926
Loa Loa (eye worm) hypothetical protein 0.0048 0.0175 0.035
Echinococcus granulosus NCK adaptor protein 0.0635 0.2913 0.2913
Brugia malayi Protein kinase domain containing protein 0.0446 0.2031 0.4068
Echinococcus multilocularis tyrosine kinase 0.1081 0.4992 0.4992
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0446 0.2032 1
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0446 0.2031 0.4068
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0069 0.0291
Loa Loa (eye worm) TK/DDR protein kinase 0.0446 0.2031 0.4068
Loa Loa (eye worm) hypothetical protein 0.0635 0.2913 0.5836
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0446 0.2031 0.2031
Trichomonas vaginalis TKL family protein kinase 0.0446 0.2031 1
Trichomonas vaginalis TKL family protein kinase 0.0446 0.2031 1
Brugia malayi SRC-1 0.1081 0.4992 1
Entamoeba histolytica protein kinase domain containing protein 0.0446 0.2031 0.3926
Entamoeba histolytica tyrosin kinase, putative 0.0446 0.2031 0.3926
Trypanosoma cruzi cytochrome P450, putative 0.0016 0.0026 0.0005
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0125 0.0565
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.0125 0.0125
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0446 0.2031 0.4068
Schistosoma mansoni suppressor of cytokine signaling 0.0635 0.2913 0.2913
Loa Loa (eye worm) hypothetical protein 0.0635 0.2913 0.5836
Entamoeba histolytica protein kinase domain containing protein 0.0446 0.2031 0.3926
Brugia malayi hypothetical protein 0.1081 0.4992 1
Loa Loa (eye worm) TK/FER protein kinase 0.0446 0.2031 0.4068
Schistosoma mansoni src-type protein tyrosine kinase-related 0.0446 0.2031 0.2031
Brugia malayi Furin-like cysteine rich region family protein 0.0446 0.2031 0.4068
Brugia malayi Protein kinase domain containing protein 0.0446 0.2031 0.4068
Echinococcus granulosus growth factor receptor bound protein 2 0.0635 0.2913 0.2913
Entamoeba histolytica hypothetical protein 0.0446 0.2031 0.3926
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0048 0.0175 0.035
Echinococcus multilocularis c src tyrosine kinase 0.1081 0.4992 0.4992
Trichomonas vaginalis CAMK family protein kinase 0.0047 0.0171 0.0795
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0044 0.0158 0.0317
Trichomonas vaginalis conserved hypothetical protein 0.0446 0.2031 1
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0635 0.2913 0.5836
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0037 0.0125 0.1967
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0125 0.0501
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0151 0.0656 0.1315
Echinococcus multilocularis tyrosine protein kinase csk 0.0446 0.2031 0.2031
Brugia malayi hypothetical protein 0.0635 0.2913 0.5836
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0446 0.2031 0.4068
Brugia malayi Variant SH3 domain containing protein 0.0635 0.2913 0.5836
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0046 0.0169 0.0169
Giardia lamblia Kinase, PLK 0.0095 0.0394 0.1259
Brugia malayi cytokine inducible SH2-containing protein 5 0.0635 0.2913 0.5836
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0069 0.0291
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0287 0.1289 0.1289
Echinococcus multilocularis tensin 0.0635 0.2913 0.2913
Trichomonas vaginalis TKL family protein kinase 0.0446 0.2031 1
Echinococcus granulosus receptor type guanylyl cyclase 0.0446 0.2031 0.2031
Trichomonas vaginalis TKL family protein kinase 0.0446 0.2031 1
Loa Loa (eye worm) TK/FAK protein kinase 0.0446 0.2031 0.4068
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.0446 0.2031 0.4068
Trichomonas vaginalis TKL family protein kinase 0.0446 0.2031 1
Trichomonas vaginalis TKL family protein kinase 0.0446 0.2031 1
Schistosoma mansoni protein kinase 0.0446 0.2031 0.2031
Brugia malayi Immunoglobulin I-set domain containing protein 0.0446 0.2031 0.4068
Schistosoma mansoni hypothetical protein 0.0048 0.0175 0.0175
Loa Loa (eye worm) SH2 domain-containing protein 0.0635 0.2913 0.5836
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0025 0.0072
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0635 0.2913 0.5836
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0124 0.0532 0.2525
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0056 0.0215 0.043
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.1081 0.4992 0.4992
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0016 0.0025 0.0025
Brugia malayi Protein kinase domain containing protein 0.0446 0.2031 0.4068
Brugia malayi intermediate filament protein 0.0056 0.0215 0.043
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0044 0.0158 0.0664
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0016 0.0029 0.0029
Schistosoma mansoni ephrin receptor 0.0446 0.2031 0.2031
Onchocerca volvulus 0.0635 0.2913 0.5836
Echinococcus multilocularis suppressor of cytokine signaling 6 0.0635 0.2913 0.2913
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.0394 0.1899
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0446 0.2031 0.2031
Plasmodium falciparum ataxin-2 like protein, putative 0.0078 0.0317 0.0026
Loa Loa (eye worm) hypothetical protein 0.0446 0.2031 0.4068
Echinococcus granulosus Smad4 0.0016 0.0029 0.0029
Onchocerca volvulus Huntingtin homolog 0.0124 0.0532 0.1066
Brugia malayi Cytochrome P450 family protein 0.0016 0.0026 0.0052
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0823 0.3791 0.3791
Echinococcus multilocularis signal transduction protein lnk realted 0.0635 0.2913 0.2913
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0113 0.051
Brugia malayi Intermediate filament tail domain containing protein 0.0056 0.0215 0.043
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0035 0.0116 0.0116
Loa Loa (eye worm) TK/FER protein kinase 0.0446 0.2031 0.4068
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.1081 0.4992 0.4992
Leishmania major protein kinase, putative 0.0446 0.2031 0.9993
Entamoeba histolytica tyrosine kinase, putative 0.0446 0.2031 0.3926
Trichomonas vaginalis TKL family protein kinase 0.0446 0.2031 1
Echinococcus multilocularis ubiquitin specific protease 41 0.0044 0.0158 0.0158
Onchocerca volvulus 0.0635 0.2913 0.5836
Entamoeba histolytica tyrosin kinase, putative 0.0446 0.2031 0.3926
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0016 0.0025 0.0025
Loa Loa (eye worm) phosphatidylinositol 3 0.0016 0.0025 0.005
Onchocerca volvulus 0.0446 0.2031 0.4068
Schistosoma mansoni tyrosine kinase 0.0446 0.2031 0.2031
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0446 0.2031 0.2031
Toxoplasma gondii LsmAD domain-containing protein 0.0078 0.0317 0.1061
Brugia malayi Tensin 0.0635 0.2913 0.5836
Onchocerca volvulus 0.0446 0.2031 0.4068
Echinococcus granulosus c src tyrosine kinase 0.1081 0.4992 0.4992
Echinococcus granulosus suppressor of cytokine signaling 7 0.0635 0.2913 0.2913
Trichomonas vaginalis TKL family protein kinase 0.0446 0.2031 1
Brugia malayi acetyltransferase, GNAT family protein 0.0287 0.1289 0.2581
Leishmania major hypothetical protein, conserved 0.0446 0.2031 0.9993
Brugia malayi Protein kinase domain containing protein 0.0446 0.2031 0.4068
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0016 0.0025 0.0025
Entamoeba histolytica receptor protein kinase, putative 0.0446 0.2031 0.3926
Schistosoma mansoni hypothetical protein 0.0635 0.2913 0.2913
Loa Loa (eye worm) STAT protein 0.0635 0.2913 0.5836
Trichomonas vaginalis bromodomain-containing protein, putative 0.0084 0.0345 0.1657
Trichomonas vaginalis TKL family protein kinase 0.0446 0.2031 1
Echinococcus multilocularis tyrosine protein kinase Fyn 0.1081 0.4992 0.4992
Brugia malayi beta-lactamase family protein 0.0037 0.0125 0.0251
Brugia malayi Smad1 0.0016 0.0029 0.0057
Entamoeba histolytica cysteine surface protein, putative 0.0446 0.2031 0.3926
Brugia malayi Protein kinase domain containing protein 0.0446 0.2031 0.4068
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.0116 0.0116
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.1081 0.4992 0.4992
Trichomonas vaginalis TKL family protein kinase 0.0446 0.2031 1
Brugia malayi cytoplasmic intermediate filament protein 0.003 0.0093 0.0186
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0082 0.0353
Trichomonas vaginalis TKL family protein kinase 0.0446 0.2031 1
Trichomonas vaginalis TKL family protein kinase 0.0446 0.2031 1
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0635 0.2913 0.5836
Brugia malayi beta-lactamase 0.0037 0.0125 0.0251
Brugia malayi N-terminal motif family protein 0.0177 0.0776 0.1555
Echinococcus multilocularis tyrosine protein kinase csk 0.0446 0.2031 0.2031
Brugia malayi SH2 domain containing protein 0.0635 0.2913 0.5836
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0069 0.0291
Brugia malayi ephrin receptor 1 precursor 0.0446 0.2031 0.4068
Trichomonas vaginalis TKL family protein kinase 0.0446 0.2031 1
Loa Loa (eye worm) hypothetical protein 0.0446 0.2031 0.4068
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0446 0.2032 0.2032
Trichomonas vaginalis TKL family protein kinase 0.0446 0.2031 1
Trichomonas vaginalis br serine/threonine-protein kinase, putative 0.0446 0.2031 1
Schistosoma mansoni tyrosine kinase 0.0446 0.2031 0.2031
Entamoeba histolytica tyrosine kinase, putative 0.0446 0.2031 0.3926
Loa Loa (eye worm) cytochrome P450 family protein 0.0016 0.0026 0.0052
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0446 0.2031 0.2031
Loa Loa (eye worm) hypothetical protein 0.0446 0.2031 0.4068
Entamoeba histolytica tyrosine kinase, putative 0.0446 0.2031 0.3926
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0446 0.2031 0.2031
Echinococcus granulosus ubiquitin specific protease 41 0.0044 0.0158 0.0158
Echinococcus granulosus tyrosine protein kinase pr2 0.0446 0.2031 0.2031
Loa Loa (eye worm) TK/KIN6 protein kinase 0.0446 0.2031 0.4068
Trichomonas vaginalis TKL family protein kinase 0.0446 0.2031 1
Trichomonas vaginalis TKL family protein kinase 0.0446 0.2031 1
Giardia lamblia Histone acetyltransferase GCN5 0.0077 0.0312 0.0824
Entamoeba histolytica hypothetical protein 0.0446 0.2031 0.3926
Brugia malayi RhoGAP domain containing protein 0.0635 0.2913 0.5836
Entamoeba histolytica protein kinase, putative 0.0446 0.2031 0.3926
Schistosoma mansoni smad1 5 8 and 0.0016 0.0029 0.0029
Brugia malayi Protein kinase domain containing protein 0.0446 0.2031 0.4068
Schistosoma mansoni tyrosine kinase 0.0446 0.2031 0.2031
Loa Loa (eye worm) hypothetical protein 0.0446 0.2031 0.4068
Loa Loa (eye worm) SRC-1 0.1081 0.4992 1
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.1081 0.4992 0.4992
Echinococcus multilocularis SH2 domain containing protein 7 0.0635 0.2913 0.2913
Echinococcus granulosus TGF beta signal transducer SmadC 0.0016 0.0029 0.0029
Loa Loa (eye worm) RGC/RGC protein kinase 0.0446 0.2031 0.4068
Echinococcus granulosus tyrosine protein kinase ABL1 0.1081 0.4992 0.4992
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0635 0.2913 0.2913
Echinococcus multilocularis N chimaerin 0.0635 0.2913 0.2913
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0046 0.0169 0.0718
Brugia malayi Protein kinase domain containing protein 0.0446 0.2031 0.4068
Schistosoma mansoni protein kinase 0.0446 0.2031 0.2031
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0113 0.051
Entamoeba histolytica tyrosine kinase, putative 0.0446 0.2031 0.3926
Trichomonas vaginalis STE family protein kinase 0.0446 0.2031 1
Onchocerca volvulus 0.1081 0.4992 1
Schistosoma mansoni protein tyrosine kinase 0.0446 0.2031 0.2031
Schistosoma mansoni growth factor receptor-bound protein 0.0635 0.2913 0.2913
Schistosoma mansoni tyrosine kinase 0.0446 0.2031 0.2031
Brugia malayi MH2 domain containing protein 0.024 0.1073 0.215
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0446 0.2031 0.2031
Trypanosoma brucei AGC/RSK family serine/threonine kinase, putative 0.0446 0.2031 0.9993
Loa Loa (eye worm) beta-lactamase 0.0037 0.0125 0.0251
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0046 0.0169 0.0338
Echinococcus multilocularis tyrosine protein kinase ABL1 0.1081 0.4992 0.4992
Trichomonas vaginalis protein tyrosine kinase, putative 0.0446 0.2031 1
Brugia malayi Protein kinase domain containing protein 0.0446 0.2031 0.4068
Trichomonas vaginalis TKL family protein kinase 0.0446 0.2031 1
Entamoeba histolytica protein kinase, putative 0.0446 0.2031 0.3926
Brugia malayi Raf kinase 0.0446 0.2031 0.4068
Echinococcus multilocularis heat shock protein 70 0.0446 0.2031 0.2031
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0019 0.0042 0.0086
Toxoplasma gondii ABC1 family protein 0.0037 0.0125 0.0063
Entamoeba histolytica protein kinase domain containing protein 0.0446 0.2031 0.3926
Trichomonas vaginalis TKL family protein kinase 0.0446 0.2031 1
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0037 0.0125 0.0251
Schistosoma mansoni hypothetical protein 0.0035 0.0116 0.0116
Loa Loa (eye worm) MH2 domain-containing protein 0.024 0.1073 0.215
Echinococcus granulosus tyrosine protein kinase Btk29A 0.1081 0.4992 0.4992
Onchocerca volvulus 0.0446 0.2031 0.4068
Trichomonas vaginalis CAMK family protein kinase 0.0047 0.0171 0.0795
Echinococcus granulosus insulin receptor 0.0446 0.2031 0.2031
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.0446 0.2031 0.2031
Echinococcus granulosus tyrosine protein kinase HCK 0.0446 0.2031 0.2031
Echinococcus multilocularis tyrosine protein kinase 0.0446 0.2031 0.2031
Trichomonas vaginalis TKL family protein kinase 0.0446 0.2031 1
Entamoeba histolytica protein kinase domain containing protein 0.0446 0.2031 0.3926
Brugia malayi SH2 domain containing protein 0.0635 0.2913 0.5836
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0046 0.0169 0.0169
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0113 0.051
Entamoeba histolytica acetyltransferase, GNAT family 0.0077 0.0312 0.0402
Giardia lamblia Protein 21.1 0.0446 0.2031 1
Echinococcus multilocularis smad 0.0016 0.0029 0.0029
Trichomonas vaginalis protein kinase atn1, putative 0.0446 0.2031 1
Loa Loa (eye worm) RGC/RGC protein kinase 0.0446 0.2031 0.4068
Trichomonas vaginalis TKL family protein kinase 0.0446 0.2031 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0093 0.0409
Entamoeba histolytica tyrosin kinase, putative 0.0446 0.2031 0.3926
Trichomonas vaginalis TKL family protein kinase 0.0446 0.2031 1
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0048 0.0175 0.0175
Loa Loa (eye worm) cytochrome P450 family protein 0.0016 0.0026 0.0052
Mycobacterium ulcerans lipase LipD 0.0037 0.0125 0.1967
Echinococcus multilocularis mothers against decapentaplegic 5 0.0016 0.0029 0.0029
Entamoeba histolytica SH2-protein kinase domain containing protein 0.1081 0.4992 1
Onchocerca volvulus 0.0037 0.0125 0.0251
Echinococcus granulosus retinal guanylyl cyclase 2 0.0446 0.2031 0.2031
Echinococcus granulosus tyrosine kinase 0.0446 0.2031 0.2031
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0446 0.2031 0.2031
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0069 0.0291
Entamoeba histolytica protein kinase, putative 0.0446 0.2031 0.3926
Echinococcus multilocularis lamin dm0 0.0056 0.0215 0.0215
Loa Loa (eye worm) intermediate filament protein 0.0056 0.0215 0.043
Trichomonas vaginalis TKL family protein kinase 0.0446 0.2031 1
Brugia malayi Protein kinase domain containing protein 0.0446 0.2031 0.4068
Loa Loa (eye worm) TK/FER protein kinase 0.1081 0.4992 1
Echinococcus multilocularis activated cdc42 kinase 1 0.0446 0.2031 0.2031
Echinococcus multilocularis musashi 0.0056 0.0215 0.0215
Loa Loa (eye worm) hypothetical protein 0.0635 0.2913 0.5836
Echinococcus granulosus retinal guanylyl cyclase 2 0.0446 0.2031 0.2031
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0044 0.0158 0.0732
Schistosoma mansoni tyrosine kinase 0.0446 0.2031 0.2031
Brugia malayi Protein kinase domain containing protein 0.0446 0.2031 0.4068
Schistosoma mansoni tensin 0.0635 0.2913 0.2913
Brugia malayi Protein kinase domain containing protein 0.0446 0.2031 0.4068
Echinococcus granulosus tyrosine protein kinase Src42A 0.1081 0.4992 0.4992
Echinococcus multilocularis SH2 domain containing adapter protein F 0.0635 0.2913 0.2913
Schistosoma mansoni lamin 0.0056 0.0215 0.0215
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.1081 0.4992 0.4992
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.0446 0.2031 0.4068
Echinococcus granulosus beta LACTamase domain containing family member 0.0037 0.0125 0.0125
Trichomonas vaginalis TKL family protein kinase 0.0446 0.2031 1
Trypanosoma cruzi target of rapamycin kinase 3 0.0037 0.0125 0.0498
Mycobacterium ulcerans beta-lactamase 0.0037 0.0125 0.1967
Schistosoma mansoni tyrosine kinase 0.0446 0.2031 0.2031
Entamoeba histolytica tyrosine kinase, putative 0.0446 0.2031 0.3926
Entamoeba histolytica protein kinase, putative 0.0446 0.2031 0.3926
Brugia malayi SH2 domain containing protein 0.1081 0.4992 1
Trichomonas vaginalis penicillin-binding protein, putative 0.0037 0.0125 0.057
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0446 0.2031 0.2031
Brugia malayi hypothetical protein 0.0446 0.2031 0.4068
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0446 0.2031 0.3926
Echinococcus multilocularis tyrosine protein kinase HCK 0.0446 0.2031 0.2031
Toxoplasma gondii aldehyde dehydrogenase 0.0124 0.0532 0.2181
Loa Loa (eye worm) TK/ABL protein kinase 0.1081 0.4992 1
Entamoeba histolytica hypothetical protein 0.0446 0.2031 0.3926
Echinococcus granulosus tyrosine protein kinase Fps85D 0.1081 0.4992 0.4992
Entamoeba histolytica protein kinase domain containing protein 0.0446 0.2031 0.3926
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0635 0.2913 0.2913
Brugia malayi Protein kinase domain containing protein 0.0446 0.2031 0.4068
Loa Loa (eye worm) acetyltransferase 0.0287 0.1289 0.2581
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0635 0.2913 0.5836
Entamoeba histolytica hypothetical protein 0.0446 0.2031 0.3926
Entamoeba histolytica protein kinase domain containing protein 0.0446 0.2031 0.3926
Trypanosoma cruzi protein kinase, putative 0.0446 0.2031 0.9993
Loa Loa (eye worm) hypothetical protein 0.0635 0.2913 0.5836
Echinococcus granulosus protein tyrosine kinase 0.0446 0.2031 0.2031
Echinococcus granulosus GPCR family 2 0.0048 0.0175 0.0175
Entamoeba histolytica serine/threonine kinase, putative 0.0446 0.2031 0.3926
Loa Loa (eye worm) hypothetical protein 0.0446 0.2031 0.4068
Loa Loa (eye worm) TK/FER protein kinase 0.1081 0.4992 1
Entamoeba histolytica protein kinase domain containing protein 0.0446 0.2031 0.3926
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0635 0.2913 0.2913
Trichomonas vaginalis conserved hypothetical protein 0.0446 0.2031 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0069 0.0291
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0635 0.2913 0.5836
Schistosoma mansoni tyrosine-protein kinase zap-70 0.0635 0.2913 0.2913
Mycobacterium ulcerans aldehyde dehydrogenase 0.0124 0.0532 1
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0048 0.0175 0.0175
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0287 0.1289 0.1289
Echinococcus multilocularis ephrin type A receptor 4 A 0.0446 0.2031 0.2031
Loa Loa (eye worm) hypothetical protein 0.0446 0.2031 0.4068
Echinococcus granulosus signal transduction protein lnk realted 0.0635 0.2913 0.2913
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0446 0.2032 1
Entamoeba histolytica protein kinase, putative 0.0446 0.2031 0.3926
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0082 0.0353
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0125 0.057
Trichomonas vaginalis TKL family protein kinase 0.0446 0.2031 1
Loa Loa (eye worm) hypothetical protein 0.0635 0.2913 0.5836
Trichomonas vaginalis TKL family protein kinase 0.0446 0.2031 1
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0044 0.0158 0.0664
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0095 0.0394 0.0789
Trichomonas vaginalis TKL family protein kinase 0.0446 0.2031 1
Brugia malayi Cytochrome P450 family protein 0.0016 0.0026 0.0052
Schistosoma mansoni tyrosine kinase 0.0446 0.2031 0.2031
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0446 0.2031 0.3926
Echinococcus multilocularis protein tyrosine kinase 0.0446 0.2031 0.2031
Brugia malayi Sex muscle abnormal protein 5 0.0635 0.2913 0.5836
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0016 0.0029 0.0029
Entamoeba histolytica protein kinase, putative 0.0446 0.2031 0.3926
Loa Loa (eye worm) hypothetical protein 0.0103 0.0433 0.0868
Trichomonas vaginalis TKL family protein kinase 0.0446 0.2031 1
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0446 0.2032 1
Schistosoma mansoni nck2/grb4 0.0635 0.2913 0.2913
Schistosoma mansoni tyrosine kinase 0.0446 0.2031 0.2031
Trypanosoma cruzi polo-like protein kinase, putative 0.0095 0.0394 0.1839
Loa Loa (eye worm) TK/FER protein kinase 0.1081 0.4992 1
Trypanosoma brucei polo-like protein kinase 0.0095 0.0394 0.1839
Trichomonas vaginalis TKL family protein kinase 0.0446 0.2031 1
Echinococcus multilocularis tyrosine protein kinase Fgr 0.1081 0.4992 0.4992
Brugia malayi SH2 domain containing protein 0.0635 0.2913 0.5836
Brugia malayi beta-lactamase family protein 0.0037 0.0125 0.0251
Giardia lamblia Kinase, NEK 0.0446 0.2031 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0113 0.051
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.1081 0.4992 0.4992
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0237 0.1059 1
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0044 0.0158 0.0085
Schistosoma mansoni tensin-related 0.0635 0.2913 0.2913
Echinococcus multilocularis epidermal growth factor receptor 0.0446 0.2031 0.2031
Echinococcus granulosus lamin dm0 0.0056 0.0215 0.0215
Entamoeba histolytica tyrosine kinase, putative 0.0446 0.2031 0.3926
Brugia malayi tRNA modification GTPase TrmE family protein 0.0635 0.2913 0.5836
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0027 0.0079 0.0079
Echinococcus multilocularis tyrosine protein kinase csk 0.0446 0.2031 0.2031
Loa Loa (eye worm) TK protein kinase 0.0446 0.2031 0.4068
Trypanosoma cruzi cytochrome P450, putative 0.0016 0.0026 0.0005
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0125 0.0501
Trypanosoma cruzi protein kinase, putative 0.0446 0.2031 0.9993
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0125 0.0565
Echinococcus granulosus tyrosine protein kinase csk 0.0446 0.2031 0.2031
Schistosoma mansoni tyrosine kinase 0.0446 0.2031 0.2031
Brugia malayi C-terminal src kinase protein 1 0.0446 0.2031 0.4068
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0446 0.2031 0.4068
Loa Loa (eye worm) RGC/RGC protein kinase 0.0446 0.2031 0.4068
Brugia malayi protein-tyrosine kinase 0.1081 0.4992 1
Entamoeba histolytica protein kinase, putative 0.0446 0.2031 0.3926
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0025 0.0072
Loa Loa (eye worm) cytochrome P450 family protein 0.0026 0.0074 0.0148
Loa Loa (eye worm) MH1 domain-containing protein 0.0016 0.0029 0.0057
Echinococcus granulosus tyrosine protein kinase Src42A 0.0635 0.2913 0.2913
Onchocerca volvulus 0.0635 0.2913 0.5836
Schistosoma mansoni tyrosine protein kinase 0.0446 0.2031 0.2031
Echinococcus granulosus smad 0.0016 0.0029 0.0029
Entamoeba histolytica protein kinase, putative 0.0446 0.2031 0.3926
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0125 0.0565
Schistosoma mansoni suppressor of cytokine signaling 0.0635 0.2913 0.2913
Trichomonas vaginalis TKL family protein kinase 0.0446 0.2031 1
Echinococcus multilocularis protein kinase 0.0446 0.2031 0.2031
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.0116 0.0116
Leishmania major hypothetical protein, conserved 0.0037 0.0125 0.0501
Schistosoma mansoni protein kinase 0.0446 0.2031 0.2031
Trypanosoma cruzi PAB1-binding protein , putative 0.0078 0.0317 0.1455
Loa Loa (eye worm) transcription factor SMAD2 0.024 0.1073 0.215
Schistosoma mansoni tensin 0.0635 0.2913 0.2913
Echinococcus multilocularis raf serine:threonine protein kinase 0.0446 0.2031 0.2031
Schistosoma mansoni protein kinase 0.0446 0.2032 0.2032
Entamoeba histolytica protein kinase domain containing protein 0.0446 0.2032 0.3929
Echinococcus multilocularis natriuretic peptide receptor 1 0.0446 0.2031 0.2031
Trichomonas vaginalis conserved hypothetical protein 0.0446 0.2031 1
Entamoeba histolytica protein kinase domain containing protein 0.0446 0.2031 0.3926
Loa Loa (eye worm) TK/FER protein kinase 0.1081 0.4992 1
Trichomonas vaginalis TKL family protein kinase 0.0446 0.2031 1
Loa Loa (eye worm) TK protein kinase 0.0446 0.2031 0.4068
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0446 0.2032 1
Loa Loa (eye worm) hypothetical protein 0.0446 0.2031 0.4068
Brugia malayi Protein kinase domain containing protein 0.0446 0.2031 0.4068
Echinococcus multilocularis SH2 motif 0.0635 0.2913 0.2913
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0125 0.057
Loa Loa (eye worm) hypothetical protein 0.0056 0.0215 0.043
Trichomonas vaginalis TKL family protein kinase 0.0446 0.2031 1
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.0446 0.2031 0.2031
Entamoeba histolytica ankyrin repeat protein 0.0446 0.2031 0.3926
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0446 0.2031 0.3926
Trichomonas vaginalis TKL family protein kinase 0.0446 0.2031 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0098 0.0432
Mycobacterium leprae conserved hypothetical protein 0.0037 0.0125 0.5
Brugia malayi Guanylyl cyclase protein 23 0.0446 0.2031 0.4068
Brugia malayi Protein kinase domain containing protein 0.0446 0.2031 0.4068
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0048 0.0175 0.0175
Entamoeba histolytica protein kinase, putative 0.0446 0.2031 0.3926
Loa Loa (eye worm) TK/RYK protein kinase 0.0446 0.2031 0.4068
Brugia malayi proto-oncogene tyrosine-protein kinase FER 0.0446 0.2031 0.4068
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.0394 0.1899
Brugia malayi STAT protein, DNA binding domain containing protein 0.0635 0.2913 0.5836
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.0394 0.1899
Trichomonas vaginalis TKL family protein kinase 0.0446 0.2031 1
Schistosoma mansoni intermediate filament proteins 0.0056 0.0215 0.0215
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0044 0.0158 0.0158
Entamoeba histolytica protein kinase, putative 0.0446 0.2031 0.3926
Echinococcus granulosus tyrosine protein kinase shark 0.1081 0.4992 0.4992
Brugia malayi Protein kinase domain containing protein 0.0446 0.2031 0.4068
Echinococcus multilocularis macrophage colony stimulating factor 1 receptor 0.0446 0.2031 0.2031
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0446 0.2031 0.2031
Loa Loa (eye worm) hypothetical protein 0.0078 0.0317 0.0635
Trichomonas vaginalis TKL family protein kinase 0.0446 0.2031 1
Onchocerca volvulus Tyrosine kinase homolog 0.0446 0.2031 0.4068
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0446 0.2031 0.4068
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.0446 0.2031 0.2031
Loa Loa (eye worm) hypothetical protein 0.0635 0.2913 0.5836
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.008 0.0347
Trichomonas vaginalis TKL family protein kinase 0.0446 0.2031 1
Brugia malayi Receptor family ligand binding region containing protein 0.0446 0.2031 0.4068
Trichomonas vaginalis TKL family protein kinase 0.0446 0.2031 1
Echinococcus multilocularis tensin 0.0635 0.2913 0.2913
Entamoeba histolytica protein kinase domain containing protein 0.0446 0.2031 0.3926
Loa Loa (eye worm) latrophilin receptor protein 2 0.0048 0.0175 0.035
Brugia malayi Protein kinase domain containing protein 0.0446 0.2031 0.4068
Onchocerca volvulus 0.0446 0.2031 0.4068
Echinococcus multilocularis tyrosine protein kinase Fyn 0.1081 0.4992 0.4992
Echinococcus granulosus activated cdc42 kinase 1 0.0446 0.2031 0.2031
Trichomonas vaginalis TKL family protein kinase 0.0446 0.2031 1
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0124 0.0532 0.0532
Schistosoma mansoni tyrosine kinase 0.0446 0.2031 0.2031
Brugia malayi MH2 domain containing protein 0.0016 0.0029 0.0057
Trichomonas vaginalis AGC family protein kinase 0.0446 0.2031 1
Loa Loa (eye worm) TK/CSK protein kinase 0.0446 0.2031 0.4068
Schistosoma mansoni protein kinase 0.0446 0.2031 0.2031
Schistosoma mansoni vav2 0.0635 0.2913 0.2913
Echinococcus granulosus tyrosine protein kinase Blk 0.1081 0.4992 0.4992
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.003 0.0093 0.0186
Brugia malayi Protein kinase domain containing protein 0.0446 0.2031 0.4068
Schistosoma mansoni tyrosine kinase 0.0446 0.2031 0.2031
Echinococcus multilocularis SH2 motif 0.0635 0.2913 0.2913
Echinococcus granulosus tyrosine protein kinase Lyn 0.1081 0.4993 0.4993
Trichomonas vaginalis conserved hypothetical protein 0.0446 0.2031 1
Loa Loa (eye worm) hypothetical protein 0.0177 0.0776 0.1555
Loa Loa (eye worm) phosphatidylinositol 3 0.0046 0.0169 0.0338
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0044 0.0158 0.0664
Schistosoma mansoni lamin 0.0056 0.0215 0.0215
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0095 0.0394 0.0394
Echinococcus granulosus N chimaerin 0.0635 0.2913 0.2913
Giardia lamblia Kinase, NEK 0.0446 0.2031 1
Schistosoma mansoni hypothetical protein 0.0035 0.0116 0.0116
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0446 0.2032 0.2032
Trichomonas vaginalis TKL family protein kinase 0.0446 0.2031 1
Onchocerca volvulus 0.1081 0.4992 1
Schistosoma mansoni hypothetical protein 0.0048 0.0175 0.0175
Trichomonas vaginalis TK family protein kinase 0.0446 0.2031 1
Echinococcus multilocularis epidermal growth factor receptor 0.0446 0.2031 0.2031
Loa Loa (eye worm) hypothetical protein 0.0027 0.0079 0.0158
Echinococcus granulosus natriuretic peptide receptor 1 0.0446 0.2031 0.2031
Loa Loa (eye worm) hypothetical protein 0.0635 0.2913 0.5836
Schistosoma mansoni hypothetical protein 0.0103 0.0433 0.0433
Entamoeba histolytica protein kinase, putative 0.0446 0.2031 0.3926
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0446 0.2031 0.4068
Entamoeba histolytica protein kinase domain containing protein 0.0446 0.2031 0.3926
Trypanosoma brucei PAB1-binding protein , putative 0.0078 0.0317 0.1455
Onchocerca volvulus 0.1081 0.4992 1
Plasmodium vivax ataxin-2 like protein, putative 0.0078 0.0317 0.1005
Schistosoma mansoni protein kinase 0.0446 0.2031 0.2031
Loa Loa (eye worm) hypothetical protein 0.0037 0.0125 0.0251
Loa Loa (eye worm) TK/FER protein kinase 0.1081 0.4992 1
Echinococcus multilocularis tyrosine protein kinase Fyn 0.1081 0.4992 0.4992
Entamoeba histolytica tyrosine kinase, putative 0.0446 0.2031 0.3926
Loa Loa (eye worm) hypothetical protein 0.0037 0.0125 0.0251
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0046 0.0169 0.0718
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.0394 0.1899
Brugia malayi hypothetical protein 0.0035 0.0116 0.0233
Entamoeba histolytica hypothetical protein 0.0446 0.2031 0.3926
Echinococcus multilocularis tyrosine protein kinase Fes:Fps 0.0446 0.2031 0.2031
Entamoeba histolytica protein kinase, putative 0.0635 0.2915 0.574
Echinococcus multilocularis growth factor receptor bound protein 2 0.0635 0.2913 0.2913
Trichomonas vaginalis TKL family protein kinase 0.0446 0.2031 1
Entamoeba histolytica serine/threonine kinase, putative 0.0446 0.2031 0.3926
Onchocerca volvulus 0.0446 0.2031 0.4068
Mycobacterium ulcerans esterase/lipase LipP 0.0037 0.0125 0.1967
Plasmodium falciparum protein kinase, putative 0.0446 0.2031 0.9992
Trichomonas vaginalis TKL family protein kinase 0.0446 0.2031 1
Trypanosoma brucei cytochrome P450, putative 0.0016 0.0026 0.0005
Echinococcus multilocularis tyrosine protein kinase Src64B 0.1081 0.4992 0.4992
Schistosoma mansoni kinase 0.0048 0.0177 0.0177
Brugia malayi bone morphogenetic protein type 1 receptor 0.0446 0.2031 0.4068
Mycobacterium ulcerans aldehyde dehydrogenase 0.0124 0.0532 1
Trichomonas vaginalis TKL family protein kinase 0.0446 0.2031 1
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.0394 0.1899
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0635 0.2913 0.2913
Plasmodium falciparum tyrosine kinase-like protein 0.0446 0.2031 0.9992
Onchocerca volvulus 0.1081 0.4992 1
Loa Loa (eye worm) TK/ALK protein kinase 0.0446 0.2031 0.4068
Trichomonas vaginalis TKL family protein kinase 0.0446 0.2031 1
Echinococcus granulosus histone acetyltransferase KAT2B 0.0084 0.0345 0.0345
Entamoeba histolytica serine/threonine kinase, putative 0.0446 0.2031 0.3926
Entamoeba histolytica tyrosine- protein kinase 2, putative 0.0446 0.2031 0.3926
Onchocerca volvulus 0.0635 0.2913 0.5836
Loa Loa (eye worm) hypothetical protein 0.0124 0.0532 0.1066
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0037 0.0125 0.0498
Trichomonas vaginalis TKL family protein kinase 0.0446 0.2031 1
Brugia malayi serine/threonine-protein kinase plk-2 0.0095 0.0394 0.0789
Brugia malayi Protein kinase domain containing protein 0.0446 0.2031 0.4068
Leishmania major cytochrome p450-like protein 0.0016 0.0026 0.0005
Brugia malayi Tyrosine-protein kinase F09A5.2 in chromosome X, putative 0.0446 0.2031 0.4068
Onchocerca volvulus Serine\/threonine kinase homolog 0.0095 0.0394 0.0789
Trypanosoma cruzi PAB1-binding protein , putative 0.0078 0.0317 0.1455
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0446 0.2031 1
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0635 0.2913 0.2913
Brugia malayi SH2 domain containing protein 0.0635 0.2913 0.5836
Brugia malayi SH2 domain containing protein 0.1081 0.4992 1
Trichomonas vaginalis TKL family protein kinase 0.0446 0.2031 1
Entamoeba histolytica protein kinase, putative 0.0446 0.2031 0.3926
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0446 0.2031 0.3926
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0635 0.2913 0.2913
Entamoeba histolytica SH2 domain containing protein 0.0635 0.2913 0.5737
Brugia malayi MH1 domain containing protein 0.0016 0.0029 0.0057
Loa Loa (eye worm) TK protein kinase 0.0446 0.2031 0.4068
Onchocerca volvulus 0.0446 0.2031 0.4068
Schistosoma mansoni smad1 5 8 and 0.0016 0.0029 0.0029
Echinococcus granulosus tyrosine protein kinase 0.0446 0.2031 0.2031
Loa Loa (eye worm) hypothetical protein 0.0055 0.021 0.0421
Loa Loa (eye worm) Smad1 0.0016 0.0029 0.0057
Entamoeba histolytica hypothetical protein 0.0446 0.2031 0.3926
Echinococcus multilocularis phosphatidylinositol 3 kinase regulatory subunit 0.0635 0.2913 0.2913
Entamoeba histolytica protein kinase, putative 0.0446 0.2031 0.3926
Echinococcus granulosus tyrosine protein kinase Srms 0.1081 0.4992 0.4992
Loa Loa (eye worm) hypothetical protein 0.0635 0.2913 0.5836
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0446 0.2031 0.9993
Echinococcus multilocularis tyrosine protein kinase Fyn 0.1081 0.4992 0.4992
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0125 0.0565
Brugia malayi MH1 domain containing protein 0.0016 0.0029 0.0057
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0446 0.2031 0.2031
Trichomonas vaginalis CAMK family protein kinase 0.0446 0.2031 1
Trichomonas vaginalis TKL family protein kinase 0.0446 0.2031 1
Trichomonas vaginalis penicillin-binding protein, putative 0.0037 0.0125 0.057
Schistosoma mansoni Smad4 0.0016 0.0029 0.0029
Toxoplasma gondii protein kinase 0.0446 0.2031 0.9993
Echinococcus multilocularis NCK adaptor protein 0.0635 0.2913 0.2913
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0158 0.0732
Echinococcus multilocularis tyrosine protein kinase Src42A 0.1081 0.4992 0.4992
Schistosoma mansoni tyrosine kinase 0.1081 0.4992 0.4992
Mycobacterium ulcerans hypothetical protein 0.0037 0.0125 0.1967
Plasmodium falciparum protein kinase, putative 0.0446 0.2031 0.9992
Trichomonas vaginalis conserved hypothetical protein 0.0446 0.2031 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0069 0.0291
Loa Loa (eye worm) TK protein kinase 0.1081 0.4992 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.008 0.0347
Schistosoma mansoni protein kinase 0.0446 0.2031 0.2031
Schistosoma mansoni tyrosine kinase 0.1081 0.4992 0.4992
Echinococcus multilocularis transfer RNA-Thr 0.0446 0.2031 0.2031
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0635 0.2913 0.2913
Entamoeba histolytica tyrosine kinase, putative 0.0446 0.2031 0.3926
Loa Loa (eye worm) hypothetical protein 0.0635 0.2913 0.5836
Entamoeba histolytica hypothetical protein 0.0446 0.2031 0.3926
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0446 0.2031 0.2031
Onchocerca volvulus Suppressor of cytokine signaling at 36E homolog 0.0635 0.2913 0.5836
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0025 0.0072
Schistosoma mansoni tyrosine kinase 0.1081 0.4992 0.4992
Schistosoma mansoni protein kinase 0.0446 0.2031 0.2031
Echinococcus granulosus expressed conserved protein 0.0635 0.2913 0.2913
Loa Loa (eye worm) TK/EGFR protein kinase 0.0446 0.2031 0.4068
Brugia malayi Variant SH3 domain containing protein 0.0635 0.2913 0.5836
Mycobacterium ulcerans aldehyde dehydrogenase 0.0124 0.0532 1
Echinococcus granulosus histone acetyltransferase KAT2B 0.0278 0.1251 0.1251
Echinococcus granulosus epidermal growth factor receptor 0.0446 0.2031 0.2031
Onchocerca volvulus 0.0635 0.2913 0.5836
Entamoeba histolytica protein kinase, putative 0.0446 0.2031 0.3926
Entamoeba histolytica protein kinase domain containing protein 0.0446 0.2031 0.3926
Echinococcus multilocularis receptor type guanylyl cyclase 0.0446 0.2031 0.2031
Echinococcus multilocularis GPCR, family 2 0.0048 0.0175 0.0175
Brugia malayi SH2 domain containing protein 0.0635 0.2913 0.5836
Onchocerca volvulus 0.0446 0.2031 0.4068
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0125 0.057
Schistosoma mansoni serine/threonine protein kinase 0.0446 0.2031 0.2031
Onchocerca volvulus 0.0446 0.2031 0.4068
Brugia malayi Calcitonin receptor-like protein seb-1 0.0151 0.0656 0.1315
Schistosoma mansoni aldehyde dehydrogenase 0.0124 0.0532 0.0532
Loa Loa (eye worm) TK/ROR protein kinase 0.0446 0.2031 0.4068
Loa Loa (eye worm) cytokine inducible SH2-containing protein 5 0.0635 0.2913 0.5836
Brugia malayi Protein kinase domain containing protein 0.1081 0.4992 1
Schistosoma mansoni aldehyde dehydrogenase 0.0124 0.0532 0.0532
Loa Loa (eye worm) TK protein kinase 0.0446 0.2031 0.4068
Schistosoma mansoni hypothetical protein 0.0635 0.2913 0.2913
Onchocerca volvulus 0.0037 0.0125 0.0251
Echinococcus granulosus lamin 0.0056 0.0215 0.0215
Echinococcus granulosus hypothetical protein 0.0635 0.2913 0.2913
Loa Loa (eye worm) hypothetical protein 0.0044 0.0158 0.0317
Entamoeba histolytica protein kinase domain containing protein 0.0446 0.2031 0.3926
Echinococcus multilocularis microtubule associated protein 2 0.2154 1 1
Echinococcus granulosus SHC transforming protein 3 0.0635 0.2913 0.2913
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0635 0.2913 0.5836
Brugia malayi Latrophilin receptor protein 2 0.0048 0.0175 0.035
Schistosoma mansoni growth factor receptor-bound protein 0.0635 0.2913 0.2913
Schistosoma mansoni tyrosine kinase 0.0446 0.2031 0.2031
Entamoeba histolytica leucine-rich repeat domain-containing protein 0.0446 0.2031 0.3926
Schistosoma mansoni serine/threonine protein kinase 0.0446 0.2031 0.2031
Brugia malayi Variant SH3 domain containing protein 0.0635 0.2913 0.5836
Entamoeba histolytica tyrosine kinase, putative 0.0446 0.2031 0.3926
Trichomonas vaginalis TKL family protein kinase 0.0446 0.2031 1
Schistosoma mansoni tyrosine kinase 0.0446 0.2031 0.2031
Echinococcus multilocularis protein KINase family member (kin 25) 0.0446 0.2031 0.2031
Echinococcus granulosus SH2 domain containing protein 7 0.0635 0.2913 0.2913
Plasmodium vivax protein kinase, putative 0.0446 0.2031 1
Trichomonas vaginalis TKL family protein kinase 0.0446 0.2031 1
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0124 0.0532 0.0532
Loa Loa (eye worm) TK/FER protein kinase 0.0446 0.2031 0.4068
Schistosoma mansoni serine/threonine protein kinase 0.0446 0.2031 0.2031
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0113 0.051
Loa Loa (eye worm) TK/FER protein kinase 0.1081 0.4992 1
Schistosoma mansoni tyrosine kinase 0.0446 0.2031 0.2031
Echinococcus granulosus SH2 domain containing adapter protein F 0.0635 0.2913 0.2913
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.0394 0.1899
Entamoeba histolytica serine/threonine kinase, putative 0.0446 0.2031 0.3926
Brugia malayi integrin-linked kinase 0.0446 0.2031 0.4068
Plasmodium falciparum ataxin-2 like protein, putative 0.0078 0.0317 0.0026
Schistosoma mansoni ephrin receptor 0.0446 0.2031 0.2031
Entamoeba histolytica tyrosine kinase, putative 0.0446 0.2031 0.3926
Echinococcus multilocularis tyrosine protein kinase Srms 0.1081 0.4992 0.4992
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0044 0.0158 0.0664
Entamoeba histolytica hypothetical protein 0.0446 0.2031 0.3926
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.1081 0.4992 0.4992
Echinococcus multilocularis tyrosine protein kinase Blk 0.1081 0.4992 0.4992
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0446 0.2031 0.3926
Echinococcus multilocularis 0.0635 0.2913 0.2913
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0044 0.0158 0.0158
Trichomonas vaginalis TKL family protein kinase 0.0446 0.2031 1
Loa Loa (eye worm) hypothetical protein 0.0124 0.0532 0.1066
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0084 0.0345 0.1154
Echinococcus multilocularis integrin linked protein kinase 0.0446 0.2031 0.2031
Onchocerca volvulus 0.0037 0.0125 0.0251
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0082 0.0353
Echinococcus granulosus tyrosine protein kinase Fyn 0.1081 0.4992 0.4992
Echinococcus granulosus integrin linked protein kinase 0.0446 0.2031 0.2031
Schistosoma mansoni tyrosine kinase 0.0446 0.2031 0.2031
Echinococcus multilocularis beta LACTamase domain containing family member 0.0037 0.0125 0.0125
Brugia malayi Protein kinase domain containing protein 0.0446 0.2031 0.4068
Trypanosoma brucei hypothetical protein, conserved 0.0037 0.0125 0.0501
Schistosoma mansoni tyrosine kinase 0.1081 0.4992 0.4992
Onchocerca volvulus 0.0635 0.2913 0.5836
Brugia malayi Immunoglobulin I-set domain containing protein 0.0446 0.2031 0.4068
Schistosoma mansoni tyrosine kinase 0.0446 0.2031 0.2031
Echinococcus multilocularis tyrosine protein kinase csk 0.0446 0.2031 0.2031
Trichomonas vaginalis TKL family protein kinase 0.0446 0.2031 1
Loa Loa (eye worm) hypothetical protein 0.0446 0.2031 0.4068
Entamoeba histolytica protein kinase domain containing protein 0.0446 0.2031 0.3926
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0016 0.0025 0.005
Echinococcus granulosus phosphatidylinositol 3 kinase regulatory subunit 0.0635 0.2913 0.2913
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0446 0.2031 0.2031
Schistosoma mansoni tyrosine kinase 0.0446 0.2031 0.2031
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0095 0.0394 0.0394
Brugia malayi Protein kinase domain containing protein 0.1081 0.4992 1
Onchocerca volvulus Huntingtin homolog 0.0124 0.0532 0.1066
Schistosoma mansoni microtubule-associated protein tau 0.2154 1 1
Trypanosoma cruzi polo-like protein kinase, putative 0.0095 0.0394 0.1839
Entamoeba histolytica hypothetical protein, conserved 0.0446 0.2031 0.3926
Echinococcus granulosus ephrin type A receptor 4 A 0.0446 0.2031 0.2031
Schistosoma mansoni tyrosine kinase 0.0446 0.2031 0.2031
Entamoeba histolytica tyrosine kinase, putative 0.0446 0.2031 0.3926
Loa Loa (eye worm) hypothetical protein 0.0037 0.0125 0.0251
Loa Loa (eye worm) hypothetical protein 0.0635 0.2913 0.5836
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0446 0.2031 0.2031
Trypanosoma brucei protein kinase, putative 0.0446 0.2032 1
Schistosoma mansoni tyrosine kinase 0.1081 0.4992 0.4992
Schistosoma mansoni shc transforming protein 0.0635 0.2913 0.2913
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0044 0.0158 0.0158
Plasmodium vivax tyrosine kinase-like protein, putative 0.0446 0.2031 1
Trichomonas vaginalis TKL family protein kinase 0.0446 0.2031 1
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0446 0.2031 0.2031
Schistosoma mansoni signal transduction protein lnk-related 0.0635 0.2913 0.2913
Brugia malayi hypothetical protein 0.0124 0.0532 0.1066
Echinococcus granulosus retinal guanylyl cyclase 2 0.0446 0.2031 0.2031
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.1081 0.4992 0.4992
Echinococcus granulosus activin receptor type 0.0446 0.2032 0.2032
Loa Loa (eye worm) TK/INSR protein kinase 0.0446 0.2031 0.4068
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0271 0.1217 0.2438
Entamoeba histolytica hypothetical protein 0.0446 0.2031 0.3926
Schistosoma mansoni tensin-related 0.0635 0.2913 0.2913
Onchocerca volvulus 0.0056 0.0215 0.043
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0446 0.2031 0.2031
Loa Loa (eye worm) hypothetical protein 0.0026 0.0074 0.0148
Entamoeba histolytica hypothetical protein 0.0446 0.2031 0.3926
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0446 0.2031 0.2031
Echinococcus multilocularis insulin receptor 0.0446 0.2031 0.2031
Loa Loa (eye worm) TK/FER protein kinase 0.1081 0.4992 1
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0095 0.0394 0.1839
Loa Loa (eye worm) TK/FER protein kinase 0.0446 0.2031 0.4068
Schistosoma mansoni protein kinase 0.0446 0.2032 0.2032
Trichomonas vaginalis TKL family protein kinase 0.0446 0.2031 1
Brugia malayi Protein kinase domain containing protein 0.0446 0.2031 0.4068
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0027 0.0079 0.0079
Loa Loa (eye worm) hypothetical protein 0.0446 0.2031 0.4068
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.0635 0.2913 0.2913
Echinococcus multilocularis SHC transforming protein 3 0.0635 0.2913 0.2913
Loa Loa (eye worm) TK protein kinase 0.0446 0.2031 0.4068
Mycobacterium leprae Probable lipase LipE 0.0037 0.0125 0.5
Loa Loa (eye worm) TK/FER protein kinase 0.0446 0.2031 0.4068
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0446 0.2031 0.3926
Entamoeba histolytica receptor protein kinase, putative 0.0446 0.2031 0.3926
Loa Loa (eye worm) hypothetical protein 0.0037 0.0125 0.0251
Trichomonas vaginalis serine-threonine protein kinase, putative 0.0446 0.2031 1
Loa Loa (eye worm) protein kinase domain-containing protein 0.0446 0.2031 0.4068
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0446 0.2031 0.2031
Entamoeba histolytica tyrosine kinase, putative 0.0446 0.2031 0.3926
Entamoeba histolytica protein kinase domain containing protein 0.0446 0.2031 0.3926
Entamoeba histolytica protein kinase domain containing protein 0.0446 0.2031 0.3926
Echinococcus multilocularis kinase suppressor of Ras 1 0.0446 0.2031 0.2031
Loa Loa (eye worm) TK/FER protein kinase 0.1081 0.4992 1
Echinococcus multilocularis protein kinase 0.0446 0.2031 0.2031
Echinococcus granulosus tensin 0.0635 0.2913 0.2913
Schistosoma mansoni tyrosine kinase 0.0446 0.2031 0.2031
Entamoeba histolytica serine/threonine protein kinase, putative 0.0095 0.0394 0.0569
Loa Loa (eye worm) TK/EPH protein kinase 0.0446 0.2031 0.4068
Schistosoma mansoni GTPase activating protein 0.0635 0.2913 0.2913
Loa Loa (eye worm) hypothetical protein 0.0635 0.2913 0.5836
Loa Loa (eye worm) hypothetical protein 0.1081 0.4992 1
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0446 0.2031 0.3926
Trichomonas vaginalis conserved hypothetical protein 0.0446 0.2031 1
Loa Loa (eye worm) CYP4Cod1 0.0016 0.0026 0.0052
Echinococcus multilocularis FL cytokine receptor 0.0446 0.2031 0.2031
Brugia malayi Protein kinase domain containing protein 0.0446 0.2031 0.4068
Brugia malayi hypothetical protein 0.0078 0.0317 0.0635
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0446 0.2031 0.2031
Loa Loa (eye worm) TK protein kinase 0.0446 0.2031 0.4068
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0022 0.0055 0.0149
Trichomonas vaginalis TKL family protein kinase 0.0446 0.2031 1
Loa Loa (eye worm) hypothetical protein 0.0151 0.0656 0.1315
Schistosoma mansoni adapter molecule crk 0.0635 0.2913 0.2913
Loa Loa (eye worm) TK/Met protein kinase 0.0446 0.2031 0.4068
Onchocerca volvulus Tyrosine kinase receptor Cad96Ca homolog 0.0446 0.2031 0.4068
Echinococcus granulosus raf serine:threonine protein kinase 0.0446 0.2031 0.2031
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0037 0.0125 0.0498
Echinococcus granulosus protein kinase 0.0446 0.2031 0.2031
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.0446 0.2031 0.4068
Entamoeba histolytica protein kinase, putative 0.0446 0.2031 0.3926
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0044 0.0158 0.0732
Loa Loa (eye worm) TK/ACK protein kinase 0.0446 0.2031 0.4068
Entamoeba histolytica tyrosin kinase, putative 0.0446 0.2031 0.3926
Loa Loa (eye worm) SH2 domain-containing protein 0.0635 0.2913 0.5836
Echinococcus granulosus intermediate filament protein 0.0056 0.0215 0.0215
Loa Loa (eye worm) serine/threonine protein kinase 0.0446 0.2031 0.4068
Echinococcus granulosus SH2 motif 0.0635 0.2913 0.2913
Echinococcus granulosus suppressor of cytokine signaling 6 0.0635 0.2913 0.2913
Echinococcus granulosus tyrosine protein kinase Src64B 0.1081 0.4992 0.4992
Entamoeba histolytica protein kinase domain containing protein 0.0446 0.2031 0.3926
Brugia malayi Protein kinase domain containing protein 0.0446 0.2031 0.4068
Schistosoma mansoni protein kinase 0.0446 0.2031 0.2031
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0446 0.2031 0.3926
Loa Loa (eye worm) hypothetical protein 0.0446 0.2031 0.4068
Brugia malayi SH2 domain containing protein 0.0635 0.2913 0.5836
Echinococcus granulosus tensin C1 domain containing phosphatase 0.0635 0.2913 0.2913
Loa Loa (eye worm) TK/FER protein kinase 0.1081 0.4992 1
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0048 0.0175 0.0175
Onchocerca volvulus 0.1081 0.4992 1
Brugia malayi SH2 domain containing protein 0.0635 0.2913 0.5836
Echinococcus granulosus fibroblast growth factor receptor 4 0.0446 0.2031 0.2031
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0446 0.2031 0.2031
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0446 0.2031 0.2031
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0044 0.0158 0.0158
Loa Loa (eye worm) hypothetical protein 0.0635 0.2913 0.5836
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0137 0.0628
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0046 0.0169 0.0718
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0046 0.0169 0.0108
Schistosoma mansoni smad 0.0016 0.0029 0.0029
Trypanosoma brucei Pseudokinase, putative 0.0446 0.2031 0.9993
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0446 0.2031 0.2031
Echinococcus multilocularis tyrosine protein kinase Abl 0.1081 0.4992 0.4992
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0025 0.0072
Entamoeba histolytica protein kinase domain containing protein 0.0446 0.2031 0.3926
Brugia malayi Protein kinase domain containing protein 0.0446 0.2031 0.4068
Brugia malayi Tyrosine-protein kinase PR2 0.0446 0.2031 0.4068
Echinococcus multilocularis tyrosine kinase 0.0446 0.2031 0.2031
Trichomonas vaginalis TKL family protein kinase 0.0446 0.2031 1
Loa Loa (eye worm) TK/FER protein kinase 0.0446 0.2031 0.4068
Schistosoma mansoni tensin 0.0635 0.2913 0.2913
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0446 0.2031 0.4068
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.0125 0.0125
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0044 0.0158 0.0158
Entamoeba histolytica serine/threonine kinase, putative 0.0446 0.2031 0.3926
Loa Loa (eye worm) hypothetical protein 0.0446 0.2031 0.4068
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.1081 0.4992 0.4992
Echinococcus granulosus epidermal growth factor receptor 0.0446 0.2031 0.2031
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0446 0.2031 0.3926
Toxoplasma gondii STE kinase 0.0446 0.2031 0.9993
Entamoeba histolytica protein kinase domain containing protein 0.0446 0.2031 0.3926
Leishmania major hypothetical protein, conserved 0.0078 0.0317 0.1455
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0446 0.2031 0.2031
Trichomonas vaginalis TKL family protein kinase 0.0446 0.2031 1
Brugia malayi hypothetical protein 0.005 0.0188 0.0376
Trichomonas vaginalis TKL family protein kinase 0.0446 0.2031 1
Trichomonas vaginalis TKL family protein kinase 0.0446 0.2031 1
Schistosoma mansoni serine/threonine protein kinase 0.0095 0.0394 0.0394
Entamoeba histolytica tyrosine kinase, putative 0.0446 0.2031 0.3926
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0037 0.0125 0.0251
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0113 0.051
Trichomonas vaginalis TKL family protein kinase 0.0446 0.2031 1
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0177 0.0776 0.1555
Trichomonas vaginalis TKL family protein kinase 0.0446 0.2031 1
Loa Loa (eye worm) hypothetical protein 0.0037 0.0125 0.0251
Brugia malayi Protein kinase domain containing protein 0.0446 0.2031 0.4068
Schistosoma mansoni hypothetical protein 0.0446 0.2031 0.2031
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0046 0.0169 0.0169
Loa Loa (eye worm) TK/FER protein kinase 0.0446 0.2031 0.4068
Onchocerca volvulus 0.0446 0.2031 0.4068
Echinococcus granulosus tyrosine protein kinase csk 0.0446 0.2031 0.2031
Trichomonas vaginalis TKL family protein kinase 0.0446 0.2031 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0025 0.0072
Entamoeba histolytica tyrosine kinase, putative 0.0446 0.2031 0.3926
Loa Loa (eye worm) TK protein kinase 0.0446 0.2031 0.4068
Schistosoma mansoni tyrosine kinase 0.0446 0.2031 0.2031
Trichomonas vaginalis TKL family protein kinase 0.0446 0.2031 1
Brugia malayi Cytochrome P450 family protein 0.0026 0.0074 0.0148
Echinococcus granulosus activated cdc42 kinase 1 0.0446 0.2031 0.2031
Entamoeba histolytica protein kinase, putative 0.0446 0.2031 0.3926
Schistosoma mansoni tyrosine kinase 0.0446 0.2031 0.2031
Schistosoma mansoni hypothetical protein 0.0048 0.0175 0.0175
Entamoeba histolytica hypothetical protein 0.0446 0.2031 0.3926
Schistosoma mansoni tyrosine kinase 0.1081 0.4992 0.4992
Loa Loa (eye worm) hypothetical protein 0.0446 0.2031 0.4068
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0635 0.2913 0.2913
Schistosoma mansoni tyrosine kinase 0.0446 0.2031 0.2031
Loa Loa (eye worm) SH2 domain-containing protein 0.0635 0.2913 0.5836
Brugia malayi Variant SH3 domain containing protein 0.0635 0.2913 0.5836
Entamoeba histolytica protein kinase domain containing protein 0.0446 0.2031 0.3926
Trichomonas vaginalis TKL family protein kinase 0.0446 0.2031 1
Trichomonas vaginalis TKL family protein kinase 0.0446 0.2031 1
Echinococcus granulosus tyrosine protein kinase csk 0.0446 0.2031 0.2031
Loa Loa (eye worm) hypothetical protein 0.0026 0.0074 0.0148
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0635 0.2915 0.574
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0046 0.0169 0.0108
Echinococcus granulosus SH2 motif 0.0635 0.2913 0.2913
Onchocerca volvulus Suppressor of cytokine signaling 7 homolog 0.0635 0.2913 0.5836
Loa Loa (eye worm) hypothetical protein 0.0635 0.2913 0.5836
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0084 0.0345 0.1208
Echinococcus multilocularis SH2 motif 0.0635 0.2913 0.2913
Schistosoma mansoni tyrosine kinase 0.0446 0.2031 0.2031
Brugia malayi MH2 domain containing protein 0.0016 0.0029 0.0057
Trichomonas vaginalis PIKK family atypical protein kinase 0.0046 0.0169 0.0785
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0635 0.2913 0.2913
Loa Loa (eye worm) hypothetical protein 0.0635 0.2913 0.5836
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0046 0.0169 0.0718
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0046 0.0169 0.0718
Trichomonas vaginalis esterase, putative 0.0037 0.0125 0.057
Loa Loa (eye worm) RGC/RGC protein kinase 0.0446 0.2031 0.4068
Echinococcus multilocularis tyrosine protein kinase shark 0.1081 0.4992 0.4992
Schistosoma mansoni SH2A 0.0635 0.2913 0.2913
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0084 0.0345 0.1657
Trichomonas vaginalis conserved hypothetical protein 0.0446 0.2031 1
Brugia malayi latrophilin 2 splice variant baaae 0.0103 0.0433 0.0868
Schistosoma mansoni serine/threonine protein kinase 0.0446 0.2031 0.2031
Echinococcus multilocularis lamin 0.0056 0.0215 0.0215
Schistosoma mansoni serine/threonine RGC 0.0446 0.2031 0.2031
Brugia malayi Protein kinase domain containing protein 0.1081 0.4992 1
Entamoeba histolytica ankyrin repeat protein 0.0446 0.2031 0.3926
Brugia malayi Tyrosine-protein kinase abl-1 0.1081 0.4992 1
Entamoeba histolytica protein kinase with ankyrin repeats, putative 0.0446 0.2031 0.3926
Entamoeba histolytica protein kinase, putative 0.0446 0.2031 0.3926
Loa Loa (eye worm) hypothetical protein 0.0635 0.2913 0.5836
Schistosoma mansoni protein kinase 0.0446 0.2032 0.2032
Trichomonas vaginalis TKL family protein kinase 0.0446 0.2031 1
Entamoeba histolytica tyrosine kinase, putative 0.0446 0.2031 0.3926
Entamoeba histolytica protein kinase, putative 0.0446 0.2031 0.3926
Echinococcus granulosus kinase suppressor of Ras 1 0.0446 0.2031 0.2031
Leishmania major protein kinase, putative 0.0446 0.2032 1
Brugia malayi Protein kinase domain containing protein 0.1081 0.4992 1
Trichomonas vaginalis serine/threonine-protein kinase wnk, putative 0.0446 0.2031 1
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.0394 0.1899
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0069 0.0291
Echinococcus granulosus tyrosine protein kinase Fyn 0.1081 0.4992 0.4992
Plasmodium falciparum protein kinase, putative 0.0446 0.2032 1
Echinococcus multilocularis activin receptor type 0.0446 0.2032 0.2032
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0446 0.2031 0.2031
Trichomonas vaginalis TKL family protein kinase 0.0446 0.2031 1
Brugia malayi Protein kinase domain containing protein 0.1081 0.4992 1
Echinococcus multilocularis tyrosine protein kinase pr2 0.0446 0.2031 0.2031
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0446 0.2031 0.3926
Entamoeba histolytica protein kinase domain containing protein 0.0446 0.2031 0.3926
Echinococcus granulosus tyrosine kinase 0.1081 0.4992 0.4992
Brugia malayi Protein kinase domain containing protein 0.0446 0.2031 0.4068
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0046 0.0169 0.0718
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0125 0.0565
Loa Loa (eye worm) TK protein kinase 0.0446 0.2031 0.4068
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.0116 0.0116
Plasmodium vivax tyrosine kinase-like protein, putative 0.0446 0.2031 1
Entamoeba histolytica protein kinase domain containing protein 0.0446 0.2031 0.3926
Schistosoma mansoni smad1 5 8 and 0.0016 0.0029 0.0029
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.0446 0.2031 0.2031
Entamoeba histolytica serine/threonine kinase, putative 0.0446 0.2031 0.3926
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0446 0.2031 0.3926
Schistosoma mansoni hypothetical protein 0.0048 0.0175 0.0175
Trichomonas vaginalis PIKK family atypical protein kinase 0.0046 0.0169 0.0785
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0151 0.0656 0.1315
Loa Loa (eye worm) MH2 domain-containing protein 0.0016 0.0029 0.0057
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0446 0.2031 0.9993
Onchocerca volvulus 0.0056 0.0215 0.043
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.0446 0.2031 0.4068
Toxoplasma gondii protein kinase domain-containing protein 0.0446 0.2031 0.9993
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0044 0.0158 0.0158
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0446 0.2031 0.3926
Giardia lamblia Kinase 0.0446 0.2031 1
Loa Loa (eye worm) TK protein kinase 0.0446 0.2031 0.4068
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0113 0.051
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0446 0.2031 0.2031
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0446 0.2031 0.3926
Schistosoma mansoni tyrosine kinase 0.0446 0.2031 0.2031
Entamoeba histolytica protein kinase, putative 0.0446 0.2031 0.3926
Loa Loa (eye worm) TK/FER protein kinase 0.1081 0.4992 1
Trichomonas vaginalis TKL family protein kinase 0.0446 0.2031 1
Echinococcus granulosus tyrosine protein kinase Fyn 0.1081 0.4992 0.4992
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0446 0.2031 0.4068
Schistosoma mansoni tyrosine kinase 0.0446 0.2031 0.2031

Activities

Activity type Activity value Assay description Source Reference
Ki (binding) = 230 uM Inhibitory activity against beta-kallikrein ChEMBL. 1507198
Ki (binding) = 230 uM Inhibitory activity against beta-kallikrein ChEMBL. 1507198

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

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