Detailed information for compound 1769543

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 211.153 | Formula: C6H14NO5P
  • H donors: 3 H acceptors: 5 LogP: -1.77 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCC(=O)N(CCCP(=O)(O)O)O
  • InChi: 1S/C6H14NO5P/c1-2-6(8)7(9)4-3-5-13(10,11)12/h9H,2-5H2,1H3,(H2,10,11,12)
  • InChiKey: WKIFNQPSYJPTSA-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma cruzi PAB1-binding protein , putative 0.0029 0.0092 0.0276
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0514 0.304 0.3975
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0053 0.007
Echinococcus granulosus thymidylate synthase 0.0105 0.0554 0.1033
Mycobacterium tuberculosis Probable thymidylate synthase ThyA (ts) (TSASE) 0.0105 0.0554 0.1483
Mycobacterium ulcerans aldehyde dehydrogenase 0.007 0.0338 0.0735
Brugia malayi beta-lactamase family protein 0.0035 0.013 0.04
Loa Loa (eye worm) hypothetical protein 0.0035 0.013 0.04
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0015 0.0009 0.0000069902
Loa Loa (eye worm) RNA binding protein 0.0073 0.0357 0.1149
Giardia lamblia Flap structure-specific endonuclease 0.003 0.0098 0.0093
Schistosoma mansoni alpha-glucosidase 0.0161 0.0894 0.1191
Trichomonas vaginalis alpha-glucosidase, putative 0.0041 0.0167 0.0219
Mycobacterium leprae Probable lipase LipE 0.0035 0.013 0.0157
Brugia malayi hypothetical protein 0.005 0.0219 0.0693
Plasmodium vivax ataxin-2 like protein, putative 0.0029 0.0092 0.0273
Trypanosoma cruzi DNA polymerase kappa, putative 0.0042 0.0171 0.0535
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0041 0.0162 0.0499
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0031 0.0102 0.0094
Echinococcus granulosus inositol monophosphatase 1 0.0038 0.0145 0.0258
Schistosoma mansoni hypothetical protein 0.0031 0.0102 0.0126
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0031 0.0102 0.0094
Loa Loa (eye worm) hypothetical protein 0.0035 0.013 0.04
Trypanosoma brucei PAB1-binding protein , putative 0.0029 0.0092 0.0276
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0191 0.1078 0.1071
Loa Loa (eye worm) hypothetical protein 0.0067 0.0319 0.1025
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0191 0.1078 0.2026
Trypanosoma brucei unspecified product 0.0029 0.0091 0.0273
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0132 0.0715 0.095
Plasmodium falciparum ataxin-2 like protein, putative 0.0029 0.0092 0.0273
Brugia malayi beta-lactamase family protein 0.0035 0.013 0.04
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0097 0.0507 0.1643
Onchocerca volvulus 0.0108 0.0572 0.6166
Schistosoma mansoni ferritin 0.0026 0.0073 0.0087
Schistosoma mansoni ap endonuclease 0.0041 0.0162 0.0206
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0027 0.0036
Entamoeba histolytica protein kinase, putative 0.0514 0.304 0.3975
Trichomonas vaginalis glucosylceramidase, putative 0.0253 0.1451 0.1901
Treponema pallidum exodeoxyribonuclease (exoA) 0.0041 0.0162 0.0152
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0053 0.007
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0031 0.0102 0.0177
Leishmania major dihydrofolate reductase-thymidylate synthase 0.0148 0.0815 0.266
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0514 0.304 0.3975
Brugia malayi serine/threonine kinase 12 0.0514 0.304 1
Mycobacterium tuberculosis Probable 1-deoxy-D-xylulose 5-phosphate reductoisomerase Dxr (DXP reductoisomerase) (1-deoxyxylulose-5-phosphate reductoisomeras 0.0125 0.0675 0.1812
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0191 0.1078 0.1439
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0015 0.0009 0.0011
Leishmania major protein kinase, putative 0.0514 0.304 1
Echinococcus granulosus dna polymerase eta 0.0042 0.0171 0.0308
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.0923 0.1209
Brugia malayi Flap endonuclease-1 0.003 0.0098 0.0296
Brugia malayi Latrophilin receptor protein 2 0.0031 0.0102 0.0308
Trypanosoma brucei ribonuclease H1 0.0022 0.0046 0.0123
Brugia malayi Glycosyl hydrolases family 31 protein 0.0041 0.0167 0.0523
Loa Loa (eye worm) carbonic anhydrase 3 0.0201 0.1136 0.372
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0041 0.0162 0.0505
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0171 0.0535
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0041 0.0162 0.0505
Schistosoma mansoni terminal deoxycytidyl transferase 0.0042 0.0171 0.0218
Brugia malayi Isocitrate dehydrogenase 0.0015 0.0009 0.0000069902
Echinococcus multilocularis inositol monophosphatase 1 0.0038 0.0145 0.0137
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0025 0.0069 0.0201
Echinococcus granulosus aurora kinase A 0.0514 0.304 0.5741
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0027 0.0036
Mycobacterium ulcerans lipase LipD 0.0035 0.013 0.0157
Trichomonas vaginalis alpha-glucosidase, putative 0.0015 0.0009 0.0011
Toxoplasma gondii exonuclease III APE 0.0041 0.0162 0.0499
Brugia malayi ImpB/MucB/SamB family protein 0.0042 0.0171 0.0535
Plasmodium falciparum ataxin-2 like protein, putative 0.0029 0.0092 0.0273
Schistosoma mansoni DNA polymerase eta 0.0042 0.0171 0.0218
Brugia malayi beta-lactamase 0.0035 0.013 0.04
Onchocerca volvulus 0.0105 0.0554 0.5965
Schistosoma mansoni cpg binding protein 0.0066 0.0313 0.041
Schistosoma mansoni importin beta-1 0.0028 0.0085 0.0104
Entamoeba histolytica hypothetical protein 0.0025 0.0069 0.008
Mycobacterium ulcerans aldehyde dehydrogenase 0.007 0.0338 0.0735
Brugia malayi Importin beta-1 subunit 0.0028 0.0085 0.0254
Mycobacterium tuberculosis Probable hydrolase 0.0035 0.013 0.0329
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0026 0.0073 0.0175
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0042 0.0171 0.0535
Plasmodium falciparum flap endonuclease 1 0.003 0.0098 0.0293
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0053 0.007
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0249 0.1429 0.4685
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0171 0.0535
Schistosoma mansoni bifunctional dihydrofolate reductase-thymidylate synthase 0.0105 0.0554 0.0734
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0019 0.0027 0.0062
Trichomonas vaginalis maltase-glucoamylase, putative 0.0041 0.0167 0.0219
Trypanosoma cruzi DNA polymerase kappa, putative 0.0042 0.0171 0.0535
Chlamydia trachomatis 1-deoxy-D-xylulose 5-phosphate reductoisomerase 0.052 0.3076 1
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.03 0.1739 0.5709
Trichomonas vaginalis ferritin, putative 0.0026 0.0073 0.0095
Plasmodium falciparum carbonic anhydrase 0.0109 0.0576 0.185
Loa Loa (eye worm) isocitrate dehydrogenase 0.0015 0.0009 0.0000069902
Schistosoma mansoni apoferritin-2 0.0026 0.0073 0.0087
Echinococcus multilocularis ferritin 0.0026 0.0073 0.0065
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0038 0.0145 0.0199
Loa Loa (eye worm) AUR protein kinase 0.0514 0.304 1
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0019 0.0027 0.0062
Echinococcus granulosus carbonic anhydrase 0.0109 0.0576 0.1075
Trichomonas vaginalis alpha-glucosidase, putative 0.0041 0.0167 0.0219
Loa Loa (eye worm) hypothetical protein 0.0109 0.0576 0.1872
Echinococcus multilocularis aurora kinase A 0.0514 0.304 0.3034
Echinococcus multilocularis expressed protein 0.0026 0.0073 0.0065
Trichomonas vaginalis flap endonuclease-1, putative 0.003 0.0098 0.0129
Echinococcus multilocularis snurportin 1 0.03 0.1739 0.1732
Loa Loa (eye worm) hypothetical protein 0.0035 0.013 0.04
Echinococcus multilocularis dihydrofolate reductase 0.0043 0.0175 0.0167
Trichomonas vaginalis ap endonuclease, putative 0.0041 0.0162 0.0212
Trypanosoma cruzi DNA polymerase eta, putative 0.0042 0.0171 0.0535
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0109 0.0576 0.1872
Schistosoma mansoni apoferritin-2 0.0026 0.0073 0.0087
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.003 0.0098 0.0296
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0019 0.0027 0.0026
Schistosoma mansoni flap endonuclease-1 0.0027 0.0081 0.0097
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0035 0.013 0.04
Onchocerca volvulus 0.0035 0.013 0.1325
Echinococcus multilocularis carbonic anhydrase 0.0109 0.0576 0.0568
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1269 0.7634 1
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0015 0.0009 0.0000069902
Entamoeba histolytica hypothetical protein 0.0035 0.0129 0.0158
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0171 0.0535
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0041 0.0162 0.0382
Onchocerca volvulus 0.0035 0.013 0.1325
Loa Loa (eye worm) hypothetical protein 0.0028 0.0085 0.0254
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0027 0.0036
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0015 0.0009 0.0011
Schistosoma mansoni ferritin 0.0026 0.0073 0.0087
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0041 0.0162 0.0201
Echinococcus granulosus carbonic anhydrase 0.0109 0.0576 0.1075
Trypanosoma brucei DNA polymerase IV, putative 0.0042 0.0171 0.0535
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.062 0.3686 1
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0015 0.0009 0.0000069902
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0019 0.0027 0.0062
Mycobacterium tuberculosis Hypothetical protein 0.005 0.0219 0.0572
Trichomonas vaginalis glucosylceramidase, putative 0.0175 0.0977 0.128
Trichomonas vaginalis conserved hypothetical protein 0.005 0.0219 0.0287
Toxoplasma gondii FATC domain-containing protein 0.0025 0.0069 0.0198
Schistosoma mansoni carbonic anhydrase-related 0.0109 0.0576 0.0764
Brugia malayi TAR-binding protein 0.0073 0.0357 0.1149
Mycobacterium leprae PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE) 0.0105 0.0554 0.1332
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0035 0.013 0.0329
Leishmania major DNA polymerase eta, putative 0.0042 0.0171 0.0535
Loa Loa (eye worm) latrophilin receptor protein 2 0.0031 0.0102 0.0308
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0038 0.0145 0.0444
Trichomonas vaginalis AGC family protein kinase 0.0514 0.304 0.3982
Mycobacterium tuberculosis Conserved protein 0.0035 0.013 0.0329
Trichomonas vaginalis inositol monophosphatase, putative 0.0038 0.0145 0.019
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0027 0.0036
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0053 0.0147
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0027 0.0036
Trypanosoma brucei ingi protein (ORF1) 0.0023 0.0057 0.016
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0019 0.0027 0.0019
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0027 0.0036
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0085 0.0254
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0191 0.1078 0.3529
Brugia malayi hypothetical protein 0.0019 0.0029 0.0068
Loa Loa (eye worm) flap endonuclease-1 0.003 0.0098 0.0296
Trypanosoma brucei carbonic anhydrase-like protein 0.0201 0.1136 0.372
Mycobacterium tuberculosis Conserved hypothetical protein 0.0042 0.0171 0.0441
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0035 0.013 0.0329
Schistosoma mansoni inositol monophosphatase 0.0038 0.0145 0.0184
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0042 0.0171 0.0308
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0041 0.0167 0.0516
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0041 0.0167 0.0219
Schistosoma mansoni serine/threonine protein kinase 0.0514 0.304 0.4077
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0041 0.0162 0.0505
Giardia lamblia Aurora kinase 0.0514 0.304 0.396
Echinococcus multilocularis neuropeptide s receptor 0.0454 0.2677 0.2671
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0041 0.0167 0.0219
Giardia lamblia Fructose-bisphosphate aldolase 0.1269 0.7634 1
Schistosoma mansoni cpg binding protein 0.0062 0.0292 0.0381
Entamoeba histolytica protein kinase, putative 0.0514 0.304 0.3975
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0027 0.0036
Echinococcus granulosus ribonuclease H1 0.0022 0.0046 0.0071
Toxoplasma gondii hypothetical protein 0.0109 0.0576 0.185
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.1269 0.7634 1
Trypanosoma cruzi PAB1-binding protein , putative 0.0029 0.0092 0.0276
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.013 0.017
Echinococcus granulosus geminin 0.0346 0.2021 0.3811
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0191 0.1078 0.1439
Brugia malayi CXXC zinc finger family protein 0.0062 0.0292 0.0935
Leishmania major importin beta-1 subunit, putative 0.0023 0.0053 0.0147
Schistosoma mansoni hypothetical protein 0.0031 0.0102 0.0126
Echinococcus multilocularis serine protein kinase ATM 0.0025 0.0069 0.0061
Leishmania major flap endonuclease-1 (FEN-1), putative 0.003 0.0098 0.0296
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0025 0.0069 0.0201
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0025 0.0069 0.0082
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0035 0.013 0.0329
Trichomonas vaginalis glucosylceramidase, putative 0.0253 0.1451 0.1901
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0027 0.0036
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0041 0.0162 0.0416
Schistosoma mansoni aldehyde dehydrogenase 0.007 0.0338 0.0444
Echinococcus multilocularis cpg binding protein 0.0066 0.0313 0.0305
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0027 0.0036
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0201 0.1136 0.372
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0171 0.0535
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0027 0.0036
Trypanosoma brucei DNA polymerase kappa, putative 0.0029 0.0091 0.0273
Mycobacterium tuberculosis Probable lipase LipE 0.0035 0.013 0.0329
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1269 0.7634 1
Brugia malayi F/Y-rich N-terminus family protein 0.0019 0.003 0.007
Loa Loa (eye worm) beta-lactamase 0.0035 0.013 0.04
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0041 0.0162 0.029
Schistosoma mansoni tar DNA-binding protein 0.0073 0.0357 0.0469
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0027 0.0036
Toxoplasma gondii ABC1 family protein 0.0035 0.013 0.0395
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0514 0.304 0.3034
Trypanosoma brucei aurora B kinase 0.0514 0.304 1
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.007 0.0338 0.1088
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.0923 0.1209
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0191 0.1078 0.1071
Loa Loa (eye worm) inositol-1 0.0038 0.0145 0.0449
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0022 0.0048 0.0129
Loa Loa (eye worm) hypothetical protein 0.0109 0.0576 0.1872
Toxoplasma gondii HEAT repeat-containing protein 0.0028 0.0085 0.0251
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0019 0.0027 0.0062
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0109 0.0576 0.1872
Trichomonas vaginalis alpha-glucosidase, putative 0.0015 0.0009 0.0011
Echinococcus multilocularis ribonuclease H1 0.0022 0.0046 0.0038
Loa Loa (eye worm) hypothetical protein 0.0097 0.0507 0.1643
Echinococcus granulosus neuropeptide receptor A26 0.0454 0.2677 0.5054
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0027 0.0036
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0019 0.0027 0.0062
Schistosoma mansoni tar DNA-binding protein 0.0073 0.0357 0.0469
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.003 0.0098 0.0296
Entamoeba histolytica hypothetical protein 0.0023 0.0053 0.0058
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0171 0.0535
Brugia malayi RNase H family protein 0.0022 0.0046 0.0123
Schistosoma mansoni phosphoglucomutase 0.0022 0.0046 0.0051
Echinococcus granulosus snurportin 1 0.03 0.1739 0.3278
Trypanosoma brucei ingi protein (ORF1) 0.0023 0.0057 0.016
Schistosoma mansoni carbonic anhydrase-related 0.0109 0.0576 0.0764
Loa Loa (eye worm) hypothetical protein 0.0042 0.0171 0.0535
Trypanosoma cruzi DNA polymerase kappa, putative 0.0042 0.0171 0.0535
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.013 0.017
Echinococcus granulosus dihydrofolate reductase 0.0043 0.0175 0.0316
Entamoeba histolytica deoxycytidyl transferase, putative 0.0042 0.0171 0.0213
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0191 0.1078 0.2026
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.013 0.04
Trypanosoma brucei retrotransposon hot spot protein 4 (RHS4), interrupted 0.0023 0.0057 0.016
Schistosoma mansoni tar DNA-binding protein 0.0073 0.0357 0.0469
Mycobacterium leprae PROBABLE 1-DEOXY-D-XYLULOSE 5-PHOSPHATE REDUCTOISOMERASE DXR (DXP REDUCTOISOMERASE) (1-DEOXYXYLULOSE-5-PHOSPHATE REDUCTOISOMERAS 0.052 0.3076 0.8312
Echinococcus multilocularis importin subunit beta 1 0.0028 0.0085 0.0077
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.007 0.0338 0.033
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0191 0.1078 0.3529
Schistosoma mansoni tar DNA-binding protein 0.0073 0.0357 0.0469
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0019 0.0027 0.0019
Schistosoma mansoni ferritin light chain 0.0026 0.0073 0.0087
Schistosoma mansoni cpg binding protein 0.0066 0.0313 0.041
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0019 0.0027 0.0025
Loa Loa (eye worm) hypothetical protein 0.0031 0.0102 0.0308
Echinococcus granulosus GPCR family 2 0.0031 0.0102 0.0177
Echinococcus granulosus tar DNA binding protein 0.0073 0.0357 0.066
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.007 0.0338 0.0625
Brugia malayi hypothetical protein 0.0035 0.0129 0.0396
Echinococcus granulosus serine protein kinase ATM 0.0025 0.0069 0.0116
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0019 0.0027 0.0025
Mycobacterium ulcerans 1-deoxy-D-xylulose 5-phosphate reductoisomerase 0.052 0.3076 0.8312
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.013 0.0163
Plasmodium vivax hypothetical protein, conserved 0.0035 0.013 0.0395
Toxoplasma gondii LsmAD domain-containing protein 0.0029 0.0092 0.0273
Brugia malayi serine/threonine protein kinase 6 0.0514 0.304 1
Brugia malayi thymidylate synthase 0.0105 0.0554 0.1799
Schistosoma mansoni dihydrofolate reductase 0.0043 0.0175 0.0225
Loa Loa (eye worm) phosphatidylinositol 3 0.0019 0.0027 0.0062
Brugia malayi MH2 domain containing protein 0.0117 0.0626 0.2037
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.007 0.0338 0.0897
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0031 0.0102 0.0177
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase 0.0148 0.0815 0.266
Entamoeba histolytica Flap nuclease, putative 0.003 0.0098 0.0118
Mycobacterium leprae DIHYDROFOLATE REDUCTASE DFRA (DHFR) (TETRAHYDROFOLATE DEHYDROGENASE) 0.0043 0.0175 0.0284
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0019 0.0027 0.0062
Echinococcus multilocularis lysosomal alpha glucosidase 0.0187 0.1052 0.1045
Echinococcus multilocularis carbonic anhydrase 0.0109 0.0576 0.0568
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0042 0.0171 0.0535
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0019 0.0027 0.0036
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0171 0.0535
Trypanosoma cruzi DNA polymerase kappa, putative 0.0042 0.0171 0.0535
Schistosoma mansoni carbonic anhydrase-related 0.0109 0.0576 0.0764
Onchocerca volvulus Ribonuclease H1 homolog 0.0022 0.0046 0.0409
Loa Loa (eye worm) CXXC zinc finger family protein 0.0062 0.0292 0.0935
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0027 0.0036
Schistosoma mansoni phosphoglucomutase 0.0022 0.0046 0.0051
Mycobacterium tuberculosis Probable esterase LipL 0.0035 0.013 0.0329
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0038 0.0145 0.019
Brugia malayi latrophilin 2 splice variant baaae 0.0067 0.0319 0.1025
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0041 0.0162 0.0153
Brugia malayi Glycosyl hydrolases family 31 protein 0.0187 0.1052 0.3442
Schistosoma mansoni protein kinase 0.0514 0.304 0.4077
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0201 0.1136 0.1517
Loa Loa (eye worm) histone methyltransferase 0.0019 0.0031 0.0075
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.013 0.017
Echinococcus granulosus ferritin 0.0026 0.0073 0.0122
Trichomonas vaginalis alpha-glucosidase, putative 0.0041 0.0167 0.0219
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0109 0.0576 0.1872
Trypanosoma brucei glucosidase, putative 0.0041 0.0167 0.0523
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0019 0.0031 0.0023
Entamoeba histolytica hypothetical protein 0.0035 0.0129 0.0158
Treponema pallidum bacterioferrin (TpF1) 0.0026 0.0073 0.0035
Trypanosoma brucei DNA polymerase IV, putative 0.0042 0.0171 0.0535
Plasmodium vivax flap endonuclease 1, putative 0.003 0.0098 0.0293
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0019 0.0027 0.0026
Trypanosoma brucei unspecified product 0.0023 0.0057 0.016
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1269 0.7634 1
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0226 0.1289 0.3482
Echinococcus granulosus importin subunit beta 1 0.0028 0.0085 0.0146
Mycobacterium ulcerans DNA polymerase IV 0.0042 0.0171 0.0271
Leishmania major phosphatidylinositol kinase related protein, putative 0.0019 0.0027 0.0062
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0027 0.0036
Echinococcus multilocularis carbonic anhydrase 0.0109 0.0576 0.0568
Schistosoma mansoni intracisternal A-particle retropepsin (A02 family) 0.1238 0.7444 1
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0019 0.0027 0.0062
Brugia malayi Calcitonin receptor-like protein seb-1 0.0097 0.0507 0.1643
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0027 0.0036
Echinococcus granulosus expressed protein 0.0026 0.0073 0.0122
Brugia malayi isocitrate dehydrogenase 0.0015 0.0009 0.0000069902
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0109 0.0576 0.1872
Entamoeba histolytica protein kinase , putative 0.0514 0.304 0.3975
Schistosoma mansoni hypothetical protein 0.0346 0.2021 0.2706
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0038 0.0145 0.019
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0027 0.0036
Loa Loa (eye worm) thymidylate synthase 0.0105 0.0554 0.1799
Loa Loa (eye worm) phosphatidylinositol 3 0.0019 0.0027 0.0062
Trypanosoma brucei RNA helicase, putative 0.0081 0.0407 0.1316
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0027 0.0036
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0034 0.0121 0.0305
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0035 0.013 0.04
Echinococcus granulosus flap endonuclease 1 0.003 0.0098 0.017
Onchocerca volvulus 0.0035 0.013 0.1325
Trichomonas vaginalis glucosylceramidase, putative 0.0253 0.1451 0.1901
Trichomonas vaginalis ap endonuclease, putative 0.0041 0.0162 0.0212
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.0129 0.012
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1269 0.7634 1
Plasmodium falciparum 1-deoxy-D-xylulose 5-phosphate reductoisomerase 0.052 0.3076 1
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0201 0.1136 0.372
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0253 0.1451 0.476
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0041 0.0162 0.0499
Plasmodium vivax bifunctional dihydrofolate reductase-thymidylate synthase, putative 0.0148 0.0815 0.2628
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0145 0.0449
Schistosoma mansoni hypothetical protein 0.0067 0.0319 0.0418
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0035 0.013 0.0157
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0201 0.1136 0.372
Loa Loa (eye worm) AUR protein kinase 0.0514 0.304 1
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0109 0.0576 0.1872
Echinococcus multilocularis carbonic anhydrase II 0.0201 0.1136 0.1129
Echinococcus multilocularis tar DNA binding protein 0.0073 0.0357 0.0349
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0085 0.0254
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0042 0.0171 0.0224
Schistosoma mansoni alpha-glucosidase 0.0161 0.0894 0.1191
Echinococcus granulosus neutral alpha glucosidase AB 0.0041 0.0167 0.03
Mycobacterium ulcerans thymidylate synthase 0.0105 0.0554 0.1332
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0019 0.0027 0.0062
Toxoplasma gondii aldehyde dehydrogenase 0.007 0.0338 0.1076
Brugia malayi RNA binding protein 0.0073 0.0357 0.1149
Trypanosoma cruzi hypothetical protein, conserved 0.0041 0.0167 0.0523
Trypanosoma brucei DNA polymerase eta, putative 0.0042 0.0171 0.0535
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0171 0.0535
Onchocerca volvulus Glucosylceramidase homolog 0.0166 0.0923 1
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0038 0.0145 0.0326
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0145 0.0449
Toxoplasma gondii histone lysine methyltransferase SET1 0.0118 0.0629 0.2024
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0019 0.0027 0.0062
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0042 0.0171 0.0163
Echinococcus multilocularis lysosomal alpha glucosidase 0.0187 0.1052 0.1045
Schistosoma mansoni family A2 unassigned peptidase (A02 family) 0.0225 0.1283 0.1715
Brugia malayi RNA, U transporter 1 0.008 0.0401 0.1293
Toxoplasma gondii target of rapamycin (TOR), putative 0.0019 0.0027 0.0061
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase, putative 0.005 0.0219 0.0693
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0019 0.0027 0.0062
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0019 0.0027 0.0062
Schistosoma mansoni hypothetical protein 0.0884 0.5289 0.7102
Trichomonas vaginalis glucosylceramidase, putative 0.0253 0.1451 0.1901
Toxoplasma gondii 1-deoxy-D-xylulose 5-phosphate reductoisomerase, putative 0.052 0.3076 1
Trypanosoma cruzi hypothetical protein, conserved 0.0041 0.0167 0.0523
Trichomonas vaginalis alpha-glucosidase, putative 0.0041 0.0167 0.0219
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0027 0.0036
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0109 0.0576 0.1872
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0027 0.0036
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.003 0.0098 0.0293
Leishmania major DNA polymerase kappa, putative 0.0042 0.0171 0.0535
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0015 0.0009 0.0001
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0514 0.304 0.3975
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0514 0.304 0.5741
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.0129 0.0228
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.0057 0.016
Brugia malayi Cytochrome P450 family protein 0.0028 0.0084 0.0249
Trichomonas vaginalis maltase-glucoamylase, putative 0.0015 0.0009 0.0011
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.013 0.017
Leishmania major ribonuclease H1, putative 0.0022 0.0046 0.0123
Echinococcus granulosus cpg binding protein 0.0066 0.0313 0.0578
Loa Loa (eye worm) hypothetical protein 0.0109 0.0576 0.1872
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0171 0.0535
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0069 0.0091
Brugia malayi hypothetical protein 0.0029 0.0092 0.0276
Brugia malayi Putative carbonic anhydrase 5 precursor 0.0201 0.1136 0.372
Mycobacterium ulcerans esterase/lipase LipP 0.0035 0.013 0.0157
Echinococcus multilocularis thymidylate synthase 0.0105 0.0554 0.0546
Mycobacterium ulcerans dihydrofolate reductase DfrA 0.0043 0.0175 0.0284
Loa Loa (eye worm) transcription factor SMAD2 0.0117 0.0626 0.2037
Trichomonas vaginalis alpha-glucosidase, putative 0.0015 0.0009 0.0011
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1269 0.7634 1
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0026 0.0073 0.0175
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.1269 0.7634 1
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0042 0.0171 0.0441
Toxoplasma gondii ribonuclease HI protein 0.0022 0.0046 0.0122
Plasmodium falciparum importin beta, putative 0.0028 0.0085 0.0251
Entamoeba histolytica protein kinase domain containing protein 0.0514 0.304 0.3975
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0027 0.0036
Leishmania major hypothetical protein, conserved 0.0029 0.0092 0.0276
Echinococcus multilocularis neuropeptide receptor A26 0.0454 0.2677 0.2671
Loa Loa (eye worm) hypothetical protein 0.0035 0.013 0.04
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.0923 0.1209
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.013 0.017
Loa Loa (eye worm) cytochrome P450 family protein 0.0028 0.0084 0.0249
Schistosoma mansoni hypothetical protein 0.0035 0.0129 0.0162
Loa Loa (eye worm) hypothetical protein 0.0035 0.013 0.04
Echinococcus granulosus neuropeptide s receptor 0.0454 0.2677 0.5054
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0027 0.0036
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0191 0.1078 0.1439
Schistosoma mansoni alpha glucosidase 0.0041 0.0167 0.0213
Schistosoma mansoni hypothetical protein 0.03 0.1739 0.2328
Wolbachia endosymbiont of Brugia malayi bacterioferritin/cytochrome b1 0.0026 0.0073 0.0089
Treponema pallidum 1-deoxy-D-xylulose 5-phosphate reductoisomerase 0.052 0.3076 0.3993
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.0923 0.1209
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0041 0.0162 0.0246
Plasmodium vivax 1-deoxy-D-xylulose 5-phosphate reductoisomerase, putative 0.052 0.3076 1
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0073 0.0357 0.1149
Mycobacterium ulcerans hypothetical protein 0.0035 0.013 0.0157
Mycobacterium tuberculosis Probable lipase LipD 0.0035 0.013 0.0329
Plasmodium vivax importin-beta 2, putative 0.0028 0.0085 0.0251
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0027 0.0036
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0038 0.0145 0.0179
Trypanosoma cruzi target of rapamycin kinase 3 0.0019 0.0027 0.0062
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0027 0.0036
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0027 0.0036
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0019 0.0027 0.0036
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0027 0.0036
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0042 0.0171 0.0218
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0027 0.0036
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0019 0.0027 0.0062
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0041 0.0162 0.0505
Onchocerca volvulus 0.0062 0.0292 0.3099
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0015 0.0009 0.0000069902
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0031 0.0102 0.0308
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.013 0.0163
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0041 0.0167 0.0208
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0041 0.0167 0.0523
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0034 0.0121 0.0132
Trypanosoma brucei hypothetical protein, conserved 0.0035 0.013 0.04
Mycobacterium tuberculosis Conserved protein 0.0035 0.013 0.0329
Plasmodium falciparum bifunctional dihydrofolate reductase-thymidylate synthase 0.0148 0.0815 0.2628
Leishmania major carbonic anhydrase-like protein 0.0201 0.1136 0.372
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0201 0.1136 0.1517
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.0923 0.1209
Loa Loa (eye worm) hypothetical protein 0.0029 0.0092 0.0276
Trichomonas vaginalis AGC family protein kinase 0.0514 0.304 0.3982
Loa Loa (eye worm) AUR protein kinase 0.0514 0.304 1
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0019 0.0027 0.0062
Trichomonas vaginalis esterase, putative 0.0035 0.013 0.017
Brugia malayi RNase H family protein 0.0022 0.0046 0.0123
Brugia malayi Dihydrofolate reductase 0.0043 0.0175 0.055
Giardia lamblia Ribonuclease H 0.0022 0.0046 0.0025
Echinococcus granulosus beta LACTamase domain containing family member 0.0035 0.013 0.023
Echinococcus multilocularis GPCR, family 2 0.0031 0.0102 0.0094
Schistosoma mansoni hypothetical protein 0.0346 0.2021 0.2706
Schistosoma mansoni hypothetical protein 0.0031 0.0102 0.0126
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0027 0.0036
Trichomonas vaginalis alpha-glucosidase, putative 0.0041 0.0167 0.0219
Giardia lamblia DINP protein human, muc B family 0.0042 0.0171 0.0189
Brugia malayi serine/threonine-protein kinase 6 0.0514 0.304 1
Leishmania major hypothetical protein, conserved 0.0035 0.013 0.04
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1269 0.7634 1
Trichomonas vaginalis glucosylceramidase, putative 0.0253 0.1451 0.1901
Trichomonas vaginalis ribonuclease H1, putative 0.0022 0.0046 0.006
Trypanosoma brucei unspecified product 0.0029 0.0091 0.0273
Trypanosoma brucei DNA polymerase kappa, putative 0.0029 0.0091 0.0273
Loa Loa (eye worm) TAR-binding protein 0.0073 0.0357 0.1149
Echinococcus multilocularis dna polymerase eta 0.0042 0.0171 0.0163
Mycobacterium tuberculosis Conserved protein 0.0035 0.013 0.0329
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0171 0.0535
Echinococcus granulosus dnaJ subfamily B 0.0884 0.5289 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0029 0.0091 0.0273
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0019 0.0027 0.0062
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0041 0.0162 0.0505
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0041 0.0167 0.0208
Trypanosoma cruzi ribonuclease H1, putative 0.0022 0.0046 0.0123
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.062 0.3686 1
Trichomonas vaginalis glucosylceramidase, putative 0.0175 0.0977 0.128
Mycobacterium ulcerans DNA polymerase IV 0.0042 0.0171 0.0271
Trichomonas vaginalis AGC family protein kinase 0.0514 0.304 0.3982
Schistosoma mansoni ferritin 0.0026 0.0073 0.0087
Echinococcus multilocularis dnaJ subfamily B 0.0884 0.5289 0.5285
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0027 0.0036
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0019 0.0027 0.0062
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0187 0.1052 0.3442
Trypanosoma brucei dihydrofolate reductase-thymidylate synthase 0.0148 0.0815 0.266
Echinococcus multilocularis beta LACTamase domain containing family member 0.0035 0.013 0.0122
Mycobacterium ulcerans beta-lactamase 0.0035 0.013 0.0157
Brugia malayi exodeoxyribonuclease III family protein 0.0041 0.0162 0.0505
Brugia malayi Inositol-1 0.0038 0.0145 0.0449
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0097 0.0507 0.1643
Brugia malayi ImpB/MucB/SamB family protein 0.0042 0.0171 0.0535
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.013 0.04
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0025 0.0069 0.0201
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.0923 0.1209
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0027 0.0036
Schistosoma mansoni tar DNA-binding protein 0.0073 0.0357 0.0469
Trichomonas vaginalis AGC family protein kinase 0.0514 0.304 0.3982
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0253 0.1451 0.476
Echinococcus granulosus carbonic anhydrase 0.0109 0.0576 0.1075
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0145 0.0449
Echinococcus multilocularis geminin 0.0346 0.2021 0.2014
Loa Loa (eye worm) dihydrofolate reductase 0.0043 0.0175 0.055
Trypanosoma brucei unspecified product 0.0042 0.0171 0.0535
Schistosoma mansoni ferritin light chain 0.0026 0.0073 0.0087
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0201 0.1136 0.372
Echinococcus granulosus carbonic anhydrase II 0.0201 0.1136 0.2136
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.062 0.3686 1
Treponema pallidum fructose-bisphosphate aldolase 0.1269 0.7634 1
Brugia malayi follicle stimulating hormone receptor 0.0249 0.1429 0.4685
Schistosoma mansoni hypothetical protein 0.0081 0.0407 0.0537
Toxoplasma gondii bifunctional dihydrofolate reductase-thymidylate synthase 0.0148 0.0815 0.2628
Trichomonas vaginalis alpha-glucosidase, putative 0.0015 0.0009 0.0011
Trypanosoma cruzi aurora B kinase, putative 0.0514 0.304 1
Echinococcus granulosus dna polymerase kappa 0.0042 0.0171 0.0308
Mycobacterium tuberculosis Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase) 0.0043 0.0175 0.0453
Leishmania major alpha glucosidase II subunit, putative 0.0041 0.0167 0.0523
Schistosoma mansoni ap endonuclease 0.0041 0.0162 0.0206
Brugia malayi RNA recognition motif domain containing protein 0.0073 0.0357 0.1149
Schistosoma mansoni phosphoglucomutase 0.0022 0.0046 0.0051
Toxoplasma gondii aurora kinase 0.0514 0.304 0.9883
Echinococcus granulosus lysosomal alpha glucosidase 0.0187 0.1052 0.1976
Entamoeba histolytica hypothetical protein 0.0035 0.0129 0.0158
Schistosoma mansoni carbonic anhydrase 0.0109 0.0576 0.0764
Mycobacterium leprae conserved hypothetical protein 0.0035 0.013 0.0157
Schistosoma mansoni hypothetical protein 0.0031 0.0102 0.0126
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1269 0.7634 1
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0015 0.0009 0.0000069902
Brugia malayi RNase H family protein 0.0022 0.0046 0.0123
Trichomonas vaginalis glucosylceramidase, putative 0.0253 0.1451 0.1901
Echinococcus multilocularis flap endonuclease 1 0.003 0.0098 0.009
Schistosoma mansoni aldehyde dehydrogenase 0.007 0.0338 0.0444
Loa Loa (eye worm) hypothetical protein 0.0035 0.013 0.04
Plasmodium falciparum serine/threonine protein kinase, putative 0.0514 0.304 0.9883
Leishmania major phosphatidylinositol 3-kinase, putative 0.0019 0.0027 0.0062
Trichomonas vaginalis DNA polymerase eta, putative 0.0042 0.0171 0.0224
Trichomonas vaginalis sucrase-isomaltase, putative 0.0041 0.0167 0.0219
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.0923 0.1209
Wolbachia endosymbiont of Brugia malayi 1-deoxy-D-xylulose 5-phosphate reductoisomerase 0.052 0.3076 1
Loa Loa (eye worm) hypothetical protein 0.0022 0.0048 0.0129
Schistosoma mansoni hypothetical protein 0.0109 0.0576 0.0764
Entamoeba histolytica hypothetical protein 0.0035 0.0129 0.0158
Trypanosoma brucei DNA polymerase IV, putative 0.0042 0.0171 0.0535
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.0129 0.0162
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0145 0.0449
Schistosoma mansoni ferritin 0.0026 0.0073 0.0087
Loa Loa (eye worm) MH2 domain-containing protein 0.0117 0.0626 0.2037
Brugia malayi dihydrofolate reductase family protein 0.0043 0.0175 0.055
Trichomonas vaginalis alpha-glucosidase, putative 0.0015 0.0009 0.0011
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0041 0.0162 0.0177
Echinococcus multilocularis dna polymerase kappa 0.0042 0.0171 0.0163
Trypanosoma cruzi ribonuclease H1, putative 0.0022 0.0046 0.0123
Mycobacterium ulcerans aldehyde dehydrogenase 0.007 0.0338 0.0735
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1269 0.7634 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0171 0.0535
Echinococcus multilocularis neutral alpha glucosidase AB 0.0041 0.0167 0.0159
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0019 0.0027 0.0062
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0514 0.304 0.9883
Schistosoma mansoni inositol monophosphatase 0.0038 0.0145 0.0184
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0019 0.0031 0.0044

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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