Detailed information for compound 1770145

Basic information

Technical information
  • TDR Targets ID: 1770145
  • Name: [1-(4-aminophenyl)ethylideneamino]thiourea
  • MW: 208.283 | Formula: C9H12N4S
  • H donors: 3 H acceptors: 0 LogP: 0.74 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: NC(=S)N/N=C(/c1ccc(cc1)N)\C
  • InChi: 1S/C9H12N4S/c1-6(12-13-9(11)14)7-2-4-8(10)5-3-7/h2-5H,10H2,1H3,(H3,11,13,14)/b12-6+
  • InChiKey: IKXKPKRBUBTOBD-WUXMJOGZSA-N  


Substructure search Similarity search

Network

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Synonyms

  • ZINC00047573

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Agaricus bisporus Tyrosinase Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0008 0.01 0.0076
Onchocerca volvulus 0.0047 0.1088 0.3754
Loa Loa (eye worm) hypothetical protein 0.0008 0.01 0.0158
Schistosoma mansoni neuropeptide F-like receptor 0.0008 0.01 0.0076
Loa Loa (eye worm) hypothetical protein 0.0005 0.0025 0.0026
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0008 0.01 0.0076
Brugia malayi hypothetical protein 0.0049 0.1136 0.1965
Echinococcus granulosus tm gpcr rhodopsin 0.0008 0.01 0.0076
Brugia malayi MH1 domain containing protein 0.0008 0.0101 0.016
Schistosoma mansoni hypothetical protein 0.0008 0.01 0.0076
Loa Loa (eye worm) hypothetical protein 0.0008 0.01 0.0158
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0054 0.1284 0.1262
Schistosoma mansoni nuclear receptor 0.0049 0.1136 0.1113
Loa Loa (eye worm) hypothetical protein 0.0008 0.01 0.0158
Brugia malayi MH2 domain containing protein 0.0008 0.0101 0.016
Echinococcus multilocularis neuropeptide s receptor 0.0008 0.01 0.0076
Loa Loa (eye worm) hypothetical protein 0.0008 0.01 0.0158
Loa Loa (eye worm) hypothetical protein 0.0103 0.2523 0.4388
Brugia malayi nuclear receptor RXR 0.0049 0.1136 0.1965
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0103 0.2523 0.2504
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0103 0.2523 0.2504
Loa Loa (eye worm) hypothetical protein 0.0049 0.1136 0.1965
Echinococcus multilocularis Smad4 0.0008 0.0101 0.0076
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0008 0.01 0.0076
Brugia malayi Nuclear hormone receptor-like 1 0.0054 0.1284 0.2225
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0103 0.2523 0.2504
Brugia malayi Serotonin receptor 0.0008 0.01 0.0158
Loa Loa (eye worm) DR-78 0.0049 0.1136 0.1965
Brugia malayi steroid hormone receptor 0.0103 0.2523 0.4388
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0103 0.2523 0.2504
Brugia malayi Smad1 0.0008 0.0101 0.016
Brugia malayi follicle stimulating hormone receptor 0.0008 0.01 0.0158
Schistosoma mansoni biogenic amine receptor 0.0008 0.01 0.0076
Brugia malayi nuclear receptor RXR 0.0054 0.1284 0.2225
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0008 0.01 0.0158
Brugia malayi MH2 domain containing protein 0.0008 0.0101 0.016
Brugia malayi latrophilin 2 splice variant baaae 0.0033 0.0739 0.1272
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0008 0.01 0.0076
Brugia malayi nuclear hormone receptor 0.0049 0.1136 0.1965
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0103 0.2523 0.2504
Echinococcus multilocularis neuropeptide receptor A26 0.0008 0.01 0.0076
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0008 0.01 0.0076
Schistosoma mansoni thyroid hormone receptor 0.0103 0.2523 0.2504
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0008 0.01 0.0076
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0103 0.2523 0.4388
Brugia malayi nuclear receptor NHR-88 0.0103 0.2523 0.4388
Brugia malayi photoreceptor-specific nuclear receptor 0.0103 0.2523 0.4388
Echinococcus granulosus histone acetyltransferase KAT2B 0.0136 0.3376 0.336
Loa Loa (eye worm) hypothetical protein 0.0008 0.01 0.0158
Schistosoma mansoni smad1 5 8 and 0.0008 0.0101 0.0076
Loa Loa (eye worm) nuclear hormone receptor 0.0049 0.1136 0.1965
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0007 0.0073 0.0048
Echinococcus multilocularis mothers against decapentaplegic 5 0.0008 0.0101 0.0076
Loa Loa (eye worm) hypothetical protein 0.0008 0.01 0.0158
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0036 0.0825 0.5
Brugia malayi Calcitonin receptor-like protein seb-1 0.0048 0.1128 0.1952
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0049 0.1136 0.1113
Echinococcus granulosus TGF beta signal transducer SmadC 0.0008 0.0101 0.0076
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0008 0.01 0.0158
Brugia malayi Hypothetical tyrosinase-like protein F21C3.2 in chromosome I 0.0111 0.2732 0.4752
Schistosoma mansoni nuclear receptor nhr-48 0.0049 0.1136 0.1113
Echinococcus multilocularis inositol monophosphatase 1 0.0036 0.0825 0.0802
Schistosoma mansoni hypothetical protein 0.0015 0.0286 0.0262
Brugia malayi ORL1-like opioid receptor 0.0008 0.01 0.0158
Onchocerca volvulus 0.0049 0.1136 0.3934
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0054 0.1284 0.1262
Loa Loa (eye worm) hypothetical protein 0.0008 0.01 0.0158
Schistosoma mansoni biogenic amine (5HT) receptor 0.0008 0.01 0.0076
Echinococcus granulosus ecdysone induced protein 78C 0.0103 0.2523 0.2504
Loa Loa (eye worm) hypothetical protein 0.0049 0.1136 0.1965
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0008 0.01 0.0076
Schistosoma mansoni steroid hormone receptor ad4bp 0.0103 0.2523 0.2504
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0008 0.01 0.0076
Brugia malayi MH2 domain containing protein 0.0118 0.2898 0.5042
Echinococcus granulosus hypothetical protein 0.0008 0.01 0.0076
Schistosoma mansoni smad1 5 8 and 0.0008 0.0101 0.0076
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0825 0.8606
Schistosoma mansoni inositol monophosphatase 0.0036 0.0825 0.0802
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0008 0.01 0.0076
Brugia malayi putative neuropeptide receptor NPR1 0.0008 0.01 0.0158
Echinococcus granulosus neuropeptides capa receptor 0.0008 0.01 0.0076
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0008 0.01 0.0076
Echinococcus multilocularis rhodopsin orphan GPCR 0.0008 0.01 0.0076
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0033 0.0728 0.5
Schistosoma mansoni hypothetical protein 0.0047 0.1088 0.1066
Entamoeba histolytica acetyltransferase, GNAT family 0.0038 0.0862 1
Onchocerca volvulus 0.0028 0.0606 0.1922
Schistosoma mansoni nuclear hormone receptor 0.0103 0.2523 0.2504
Echinococcus multilocularis g protein coupled receptor 0.0008 0.01 0.0076
Brugia malayi hypothetical protein 0.0008 0.01 0.0158
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0008 0.01 0.0076
Brugia malayi orphan nuclear receptor NR2E1 0.0049 0.1136 0.1965
Loa Loa (eye worm) hypothetical protein 0.0103 0.2523 0.4388
Brugia malayi PHD-finger family protein 0.0005 0.0025 0.0026
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0008 0.01 0.0076
Schistosoma mansoni amine GPCR 0.0008 0.01 0.0076
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0036 0.0825 0.5
Echinococcus multilocularis rhodopsin orphan GPCR 0.0008 0.01 0.0076
Loa Loa (eye worm) MH1 domain-containing protein 0.0008 0.0101 0.016
Echinococcus granulosus cpg binding protein 0.0029 0.0647 0.0623
Schistosoma mansoni cpg binding protein 0.0029 0.0647 0.0623
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0054 0.1284 0.1262
Loa Loa (eye worm) hypothetical protein 0.0103 0.2523 0.4388
Echinococcus multilocularis neuropeptide Y receptor 0.0008 0.01 0.0076
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0103 0.2523 0.4388
Schistosoma mansoni nuclear hormone receptor 0.0049 0.1136 0.1113
Onchocerca volvulus 0.0049 0.1136 0.3934
Echinococcus granulosus histone acetyltransferase KAT2B 0.0041 0.095 0.0927
Loa Loa (eye worm) hypothetical protein 0.0008 0.01 0.0158
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0103 0.2523 0.4388
Loa Loa (eye worm) G-protein coupled receptor 0.0008 0.01 0.0158
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0103 0.2523 0.2504
Schistosoma mansoni hypothetical protein 0.0015 0.0286 0.0262
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0103 0.2523 0.4388
Echinococcus multilocularis cpg binding protein 0.0029 0.0647 0.0623
Echinococcus granulosus Smad4 0.0008 0.0101 0.0076
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0103 0.2523 0.2504
Schistosoma mansoni cpg binding protein 0.0028 0.0606 0.0583
Loa Loa (eye worm) hypothetical protein 0.0049 0.1136 0.1965
Loa Loa (eye worm) hypothetical protein 0.0054 0.1284 0.2225
Schistosoma mansoni coup transcription factor 0.0103 0.2523 0.2504
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0008 0.01 0.0076
Brugia malayi neuropeptide F receptor 0.0008 0.01 0.0158
Echinococcus multilocularis survival motor neuron protein 1 0.0229 0.5738 0.5727
Brugia malayi Inositol-1 0.0036 0.0825 0.1423
Loa Loa (eye worm) hypothetical protein 0.0008 0.01 0.0158
Loa Loa (eye worm) hypothetical protein 0.0008 0.01 0.0158
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.1027 0.1004
Echinococcus multilocularis neuropeptide receptor 0.0008 0.01 0.0076
Brugia malayi Dopamine receptor protein 2 0.0008 0.01 0.0158
Loa Loa (eye worm) ShTK domain-containing protein 0.0111 0.2732 0.4752
Loa Loa (eye worm) hypothetical protein 0.0111 0.2732 0.4752
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0103 0.2523 0.4388
Schistosoma mansoni myosin xvIII 0.0008 0.01 0.0076
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0103 0.2523 0.4388
Schistosoma mansoni amine GPCR 0.0008 0.01 0.0076
Brugia malayi ecdysone receptor 0.0049 0.1136 0.1965
Echinococcus granulosus G protein coupled receptor 139 0.0008 0.01 0.0076
Schistosoma mansoni hypothetical protein 0.0008 0.01 0.0076
Echinococcus multilocularis neuropeptide receptor 0.0214 0.5354 0.5343
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0041 0.095 1
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0008 0.01 0.0076
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0008 0.01 0.0076
Loa Loa (eye worm) hypothetical protein 0.0229 0.5738 1
Brugia malayi G-protein coupled receptor 0.0008 0.01 0.0158
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0825 0.5
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0008 0.01 0.0158
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0049 0.1136 0.1113
Echinococcus granulosus allatostatin A receptor 0.0008 0.01 0.0076
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0103 0.2523 0.4388
Brugia malayi hypothetical protein 0.0054 0.1284 0.2225
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0008 0.01 0.0158
Echinococcus multilocularis neuropeptide Y receptor 0.0008 0.01 0.0076
Schistosoma mansoni neuropeptide f receptor 76f 0.0008 0.01 0.0076
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0049 0.1136 0.1965
Echinococcus multilocularis G protein coupled receptor 139 0.0214 0.5354 0.5343
Echinococcus granulosus rhodopsin orphan GPCR 0.0008 0.01 0.0076
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0103 0.2523 0.2504
Schistosoma mansoni retinoic acid receptor RXR 0.0103 0.2523 0.2504
Loa Loa (eye worm) hypothetical protein 0.0049 0.1136 0.1965
Echinococcus granulosus neuropeptide receptor 0.0008 0.01 0.0076
Echinococcus multilocularis dnaJ subfamily B 0.0396 1 1
Brugia malayi neuropeptide F receptor 0.0008 0.01 0.0158
Loa Loa (eye worm) hypothetical protein 0.0049 0.1136 0.1965
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0103 0.2523 0.4388
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0008 0.01 0.0076
Brugia malayi hypothetical protein 0.0008 0.01 0.0158
Echinococcus multilocularis thyroid hormone receptor alpha 0.0103 0.2523 0.2504
Echinococcus multilocularis neuropeptides capa receptor 0.0008 0.01 0.0076
Echinococcus granulosus survival motor neuron protein 1 0.0229 0.5738 0.5727
Echinococcus granulosus 7TM GPCR rhodopsin 0.0008 0.01 0.0076
Loa Loa (eye worm) hypothetical protein 0.0008 0.01 0.0158
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0049 0.1136 0.3934
Brugia malayi hypothetical protein 0.0008 0.01 0.0158
Loa Loa (eye worm) Smad1 0.0008 0.0101 0.016
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0008 0.01 0.0076
Schistosoma mansoni amine GPCR 0.0008 0.01 0.0076
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0008 0.0101 0.0076
Loa Loa (eye worm) hypothetical protein 0.0048 0.1128 0.1952
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0008 0.01 0.0158
Echinococcus granulosus rhodopsin orphan GPCR 0.0008 0.01 0.0076
Echinococcus multilocularis neuropeptides capa receptor 0.0008 0.01 0.0076
Echinococcus granulosus tm gpcr rhodopsin 0.0008 0.01 0.0076
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0008 0.01 0.0076
Schistosoma mansoni smad1 5 8 and 0.0008 0.0101 0.0076
Toxoplasma gondii histone lysine methyltransferase SET1 0.0056 0.1328 1
Loa Loa (eye worm) G-protein coupled receptor 0.0008 0.01 0.0158
Brugia malayi Nuclear hormone receptor-like 1 0.0103 0.2523 0.4388
Schistosoma mansoni neuropeptide receptor 0.0214 0.5354 0.5343
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0008 0.01 0.0076
Schistosoma mansoni biogenic amine receptor 0.0008 0.01 0.0076
Brugia malayi hypothetical protein 0.0008 0.01 0.0158
Loa Loa (eye worm) ShTK domain-containing protein 0.0111 0.2732 0.4752
Brugia malayi Tachykinin-like peptides receptor 99D 0.0008 0.01 0.0158
Echinococcus granulosus thyroid hormone receptor alpha 0.0049 0.1136 0.1113
Brugia malayi acetyltransferase, GNAT family protein 0.014 0.3477 0.6053
Loa Loa (eye worm) hypothetical protein 0.0008 0.01 0.0158
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0059 0.1401 0.138
Loa Loa (eye worm) hypothetical protein 0.0008 0.01 0.0158
Onchocerca volvulus 0.0103 0.2523 0.9206
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0008 0.01 0.0076
Loa Loa (eye worm) inositol-1 0.0036 0.0825 0.1423
Echinococcus granulosus mixed lineage leukemia protein mll 0.0007 0.0073 0.0048
Loa Loa (eye worm) hypothetical protein 0.0008 0.01 0.0158
Brugia malayi Nuclear hormone receptor-like 1 0.0054 0.1284 0.2225
Loa Loa (eye worm) hypothetical protein 0.0049 0.1136 0.1965
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.014 0.3477 0.3461
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0007 0.0073 0.0048
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0054 0.1284 0.2225
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0049 0.1136 0.1113
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0044 0.1027 0.1004
Schistosoma mansoni amine GPCR 0.0008 0.01 0.0076
Echinococcus multilocularis sex peptide receptor 0.0008 0.01 0.0076
Loa Loa (eye worm) hypothetical protein 0.0008 0.01 0.0158
Loa Loa (eye worm) hypothetical protein 0.0054 0.1284 0.2225
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0033 0.0728 0.5
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0008 0.01 0.0076
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0015 0.0286 0.0483
Loa Loa (eye worm) hypothetical protein 0.0008 0.01 0.0158
Loa Loa (eye worm) hypothetical protein 0.0103 0.2523 0.4388
Echinococcus granulosus sex peptide receptor 0.0008 0.01 0.0076
Echinococcus granulosus rhodopsin orphan GPCR 0.0008 0.01 0.0076
Loa Loa (eye worm) hypothetical protein 0.0103 0.2523 0.4388
Loa Loa (eye worm) hypothetical protein 0.0008 0.01 0.0158
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0049 0.1136 0.1113
Brugia malayi Serotonin receptor 0.0008 0.01 0.0158
Echinococcus granulosus dro:myosuppressin receptor 0.0008 0.01 0.0076
Echinococcus granulosus tm gpcr rhodopsin 0.0008 0.01 0.0076
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0008 0.01 0.0076
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0103 0.2523 0.4388
Loa Loa (eye worm) melatonin receptor type 1A 0.0008 0.01 0.0158
Echinococcus multilocularis GPCR, family 2 0.0015 0.0286 0.0262
Brugia malayi CXXC zinc finger family protein 0.0028 0.0606 0.1041
Echinococcus granulosus mothers against decapentaplegic 5 0.0008 0.0101 0.0076
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0044 0.1027 0.1775
Loa Loa (eye worm) hypothetical protein 0.0008 0.01 0.0158
Echinococcus granulosus alpha 1A adrenergic receptor 0.0008 0.01 0.0076
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0008 0.01 0.0076
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0008 0.01 0.0076
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0103 0.2523 0.2504
Schistosoma mansoni biogenic amine receptor 0.0008 0.01 0.0076
Echinococcus multilocularis serotonin receptor 0.0008 0.01 0.0076
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0103 0.2523 0.4388
Echinococcus granulosus g protein coupled receptor 0.0008 0.01 0.0076
Brugia malayi putative neuropeptide receptor 0.0008 0.01 0.0158
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0008 0.01 0.0076
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0103 0.2523 0.2504
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0825 0.5
Echinococcus multilocularis somatostatin receptor 0.0008 0.01 0.0076
Schistosoma mansoni neuropeptide F-like receptor 0.0008 0.01 0.0076
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0049 0.1136 0.1113
Echinococcus granulosus smad 0.0008 0.0101 0.0076
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0008 0.01 0.0076
Echinococcus granulosus fmrfamide receptor 0.0008 0.01 0.0076
Loa Loa (eye worm) hypothetical protein 0.0008 0.01 0.0158
Loa Loa (eye worm) hypothetical protein 0.0008 0.01 0.0158
Echinococcus granulosus neuropeptide receptor A26 0.0008 0.01 0.0076
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0007 0.0073 0.0048
Schistosoma mansoni hypothetical protein 0.0015 0.0286 0.0262
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0103 0.2523 0.2504
Onchocerca volvulus Protein ultraspiracle homolog 0.0103 0.2523 0.9206
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0015 0.0286 0.0262
Onchocerca volvulus 0.0111 0.2732 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.1027 0.1004
Onchocerca volvulus 0.0111 0.2732 1
Loa Loa (eye worm) hypothetical protein 0.0008 0.01 0.0158
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0015 0.0286 0.0262
Loa Loa (eye worm) hypothetical protein 0.0008 0.01 0.0158
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0049 0.1136 0.3934
Echinococcus granulosus biogenic amine 5HT receptor 0.0008 0.01 0.0076
Echinococcus granulosus g-protein coupled receptor 0.0008 0.01 0.0076
Brugia malayi Nuclear hormone receptor E75 0.0049 0.1136 0.1965
Loa Loa (eye worm) hypothetical protein 0.0111 0.2732 0.4752
Loa Loa (eye worm) hypothetical protein 0.0049 0.1136 0.1965
Loa Loa (eye worm) neuropeptide F receptor 0.0008 0.01 0.0158
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0103 0.2523 0.4388
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0103 0.2523 0.2504
Echinococcus granulosus 7tm_1 domain containing protein 0.0008 0.01 0.0076
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0015 0.0286 0.0262
Echinococcus multilocularis nuclear receptor nhr 48 0.0049 0.1136 0.1113
Loa Loa (eye worm) histone methyltransferase 0.0009 0.0116 0.0186
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0009 0.0116 0.0092
Brugia malayi hypothetical protein 0.0008 0.01 0.0158
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0008 0.01 0.0158
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0103 0.2523 0.2504
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0008 0.01 0.0076
Loa Loa (eye worm) hypothetical protein 0.0008 0.01 0.0158
Loa Loa (eye worm) MH2 domain-containing protein 0.0008 0.0101 0.016
Echinococcus granulosus rhodopsin orphan GPCR 0.0008 0.01 0.0076
Brugia malayi MH1 domain containing protein 0.0008 0.0101 0.016
Loa Loa (eye worm) hypothetical protein 0.0008 0.01 0.0158
Loa Loa (eye worm) hypothetical protein 0.0008 0.01 0.0158
Loa Loa (eye worm) steroid hormone receptor 0.0103 0.2523 0.4388
Schistosoma mansoni adenoreceptor 0.0008 0.01 0.0076
Echinococcus granulosus neuropeptide s receptor 0.0008 0.01 0.0076
Echinococcus multilocularis dro:myosuppressin receptor 0.0008 0.01 0.0076
Loa Loa (eye worm) acetyltransferase 0.014 0.3477 0.6053
Schistosoma mansoni tyrosinase precursor 0.0111 0.2732 0.2714
Brugia malayi hypothetical protein 0.0008 0.01 0.0158
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0008 0.01 0.0076
Echinococcus granulosus nuclear receptor nhr 48 0.0049 0.1136 0.1113
Brugia malayi hypothetical protein 0.0049 0.1136 0.1965
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0103 0.2523 0.4388
Schistosoma mansoni growth hormone secretagogue receptor 0.0008 0.01 0.0076
Brugia malayi Hypothetical tyrosinase-like protein C02C2.1 in chromosome III 0.0111 0.2732 0.4752
Loa Loa (eye worm) hypothetical protein 0.0049 0.1136 0.1965
Loa Loa (eye worm) hypothetical protein 0.0015 0.0286 0.0483
Brugia malayi G-protein coupled receptor 0.0008 0.01 0.0158
Loa Loa (eye worm) hypothetical protein 0.0008 0.01 0.0158
Echinococcus granulosus Nuclear hormone receptor HR96 0.0049 0.1136 0.1113
Echinococcus multilocularis rhodopsin orphan GPCR 0.0008 0.01 0.0076
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0008 0.01 0.0076
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0008 0.01 0.0076
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0049 0.1136 0.1113
Loa Loa (eye worm) hypothetical protein 0.0008 0.01 0.0158
Echinococcus multilocularis G-protein coupled receptor, putative 0.0008 0.01 0.0076
Trichomonas vaginalis inositol monophosphatase, putative 0.0036 0.0825 0.8606
Loa Loa (eye worm) MH2 domain-containing protein 0.0118 0.2898 0.5042
Echinococcus multilocularis FTZ F1 alpha 0.0103 0.2523 0.2504
Brugia malayi hypothetical protein 0.0054 0.1284 0.2225
Brugia malayi Dopamine receptor 0.0008 0.01 0.0158
Schistosoma mansoni hypothetical protein 0.0008 0.01 0.0076
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0103 0.2523 0.2504
Loa Loa (eye worm) hypothetical protein 0.0054 0.1284 0.2225
Loa Loa (eye worm) hypothetical protein 0.0008 0.01 0.0158
Schistosoma mansoni cpg binding protein 0.0029 0.0647 0.0623
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0103 0.2523 0.9206
Loa Loa (eye worm) latrophilin receptor protein 2 0.0015 0.0286 0.0483
Echinococcus granulosus somatostatin receptor 0.0008 0.01 0.0076
Echinococcus granulosus serotonin receptor 0.0008 0.01 0.0076
Schistosoma mansoni alpha-1 adrenergic receptor 0.0008 0.01 0.0076
Loa Loa (eye worm) hypothetical protein 0.0008 0.01 0.0158
Brugia malayi AKH receptor 0.0008 0.01 0.0158
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0008 0.01 0.0076
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0049 0.1136 0.1113
Brugia malayi larval opioid receptor 0.0008 0.01 0.0158
Schistosoma mansoni hypothetical protein 0.0396 1 1
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0041 0.095 0.2472
Brugia malayi hypothetical protein 0.0008 0.01 0.0158
Loa Loa (eye worm) transcription factor SMAD2 0.0118 0.2898 0.5042
Echinococcus granulosus inositol monophosphatase 1 0.0036 0.0825 0.0802
Echinococcus multilocularis rhodopsin orphan GPCR 0.0008 0.01 0.0076
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0048 0.1128 0.1952
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0103 0.2523 0.4388
Brugia malayi Steroid receptor seven-up type 2 0.0103 0.2523 0.4388
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0049 0.1136 0.1113
Loa Loa (eye worm) hypothetical protein 0.0008 0.01 0.0158
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0008 0.01 0.0076
Echinococcus multilocularis g protein coupled receptor 0.0008 0.01 0.0076
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0103 0.2523 0.4388
Schistosoma mansoni neuropeptide receptor 0.0008 0.01 0.0076
Brugia malayi F/Y-rich N-terminus family protein 0.0008 0.0113 0.0181
Echinococcus granulosus biogenic amine 5HT receptor 0.0008 0.01 0.0076
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0049 0.1136 0.1113
Schistosoma mansoni nuclear receptor 0.0049 0.1136 0.1113
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0008 0.01 0.0076
Schistosoma mansoni amine GPCR 0.0008 0.01 0.0076
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0103 0.2523 0.2504
Brugia malayi nuclear receptor NHR-67 0.0049 0.1136 0.1965
Echinococcus multilocularis orexin receptor type 2 0.0008 0.01 0.0076
Brugia malayi Dopamine receptor protein 1 0.0008 0.01 0.0158
Echinococcus granulosus tachykinin peptides receptor 99D 0.0008 0.01 0.0076
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0041 0.095 0.2472
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0008 0.01 0.0076
Loa Loa (eye worm) tyrosinase 1 0.0111 0.2732 0.4752
Loa Loa (eye worm) hypothetical protein 0.0008 0.01 0.0158
Brugia malayi hypothetical protein 0.0008 0.01 0.0158
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0008 0.01 0.0158
Brugia malayi Common central domain of tyrosinase family protein 0.0111 0.2732 0.4752
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0008 0.01 0.0158
Brugia malayi G protein-coupled receptor F59B2.13 0.0008 0.01 0.0158
Onchocerca volvulus Bile acid receptor homolog 0.0103 0.2523 0.9206
Brugia malayi ecdysteroid receptor 0.0103 0.2523 0.4388
Schistosoma mansoni biogenic amine (5HT) receptor 0.0008 0.01 0.0076
Echinococcus granulosus neuropeptide Y receptor 0.0008 0.01 0.0076
Echinococcus granulosus GPCR family 2 0.0015 0.0286 0.0262
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0103 0.2523 0.2504
Loa Loa (eye worm) hypothetical protein 0.0054 0.1284 0.2225
Echinococcus multilocularis ecdysone induced protein 78C 0.0103 0.2523 0.2504
Echinococcus granulosus neuropeptide Y receptor 0.0008 0.01 0.0076
Loa Loa (eye worm) hypothetical protein 0.0008 0.01 0.0158
Loa Loa (eye worm) hypothetical protein 0.0008 0.01 0.0158
Echinococcus multilocularis fmrfamide receptor 0.0008 0.01 0.0076
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0008 0.01 0.0076
Loa Loa (eye worm) hypothetical protein 0.0008 0.01 0.0158
Schistosoma mansoni opsin-like receptor 0.0008 0.01 0.0076
Loa Loa (eye worm) hypothetical protein 0.0008 0.01 0.0158
Brugia malayi hypothetical protein 0.0008 0.01 0.0158
Echinococcus granulosus neuropeptide receptor 0.0214 0.5354 0.5343
Echinococcus multilocularis allatostatin A receptor 0.0008 0.01 0.0076
Loa Loa (eye worm) TYRA-2 protein 0.0008 0.01 0.0158
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0008 0.01 0.0076
Echinococcus multilocularis g protein coupled receptor 0.0008 0.01 0.0076
Schistosoma mansoni hypothetical protein 0.0033 0.0739 0.0715
Onchocerca volvulus 0.0111 0.2732 1
Loa Loa (eye worm) hypothetical protein 0.0049 0.1136 0.1965
Schistosoma mansoni tyrosinase precursor 0.0111 0.2732 0.2714
Echinococcus granulosus orexin receptor type 2 0.0008 0.01 0.0076
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0103 0.2523 0.4388
Echinococcus multilocularis smad 0.0008 0.0101 0.0076
Schistosoma mansoni inositol monophosphatase 0.0036 0.0825 0.0802
Brugia malayi tailless protein 0.0049 0.1136 0.1965
Echinococcus granulosus neuropeptides capa receptor 0.0008 0.01 0.0076
Schistosoma mansoni neuropeptide receptor 0.0008 0.01 0.0076
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.1027 0.1004
Loa Loa (eye worm) hypothetical protein 0.0008 0.01 0.0158
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0103 0.2523 0.2504
Loa Loa (eye worm) nuclear receptor NHR-67 0.0049 0.1136 0.1965
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0008 0.01 0.0158
Loa Loa (eye worm) hypothetical protein 0.0008 0.01 0.0158
Echinococcus granulosus g protein coupled receptor 0.0008 0.01 0.0076
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0044 0.1027 0.1004
Brugia malayi RE15519p 0.0008 0.01 0.0158
Loa Loa (eye worm) hypothetical protein 0.0008 0.01 0.0158
Loa Loa (eye worm) hypothetical protein 0.0049 0.1136 0.1965
Echinococcus granulosus Nuclear hormone receptor HR96 0.0049 0.1136 0.1113
Brugia malayi Hypothetical tyrosinase-like protein C02C2.1 in chromosome III 0.0111 0.2732 0.4752
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0008 0.01 0.0158
Brugia malayi Latrophilin receptor protein 2 0.0015 0.0286 0.0483
Brugia malayi nuclear hormone receptor family member odr-7 0.0049 0.1136 0.1965
Giardia lamblia Histone acetyltransferase GCN5 0.0038 0.0862 0.5
Loa Loa (eye worm) hypothetical protein 0.0054 0.1284 0.2225
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0041 0.095 1
Echinococcus multilocularis serotonin receptor 0.0008 0.01 0.0076
Schistosoma mansoni hypothetical protein 0.0015 0.0286 0.0262
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0008 0.01 0.0076
Schistosoma mansoni smad 0.0008 0.0101 0.0076
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0103 0.2523 0.4388
Schistosoma mansoni zinc finger protein 0.0049 0.1136 0.1113
Brugia malayi conserved hypotetical protein 0.0049 0.1136 0.1965
Schistosoma mansoni opsin-like receptor 0.0008 0.01 0.0076
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0008 0.0101 0.0076
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0007 0.0073 0.0048
Loa Loa (eye worm) hypothetical protein 0.0008 0.01 0.0158
Brugia malayi sulfakinin receptor protein 0.0008 0.01 0.0158
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0008 0.01 0.0076
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0015 0.0286 0.0262
Brugia malayi nuclear hormone receptor 0.0103 0.2523 0.4388
Schistosoma mansoni Smad4 0.0008 0.0101 0.0076
Schistosoma mansoni thyroid hormone receptor 0.0103 0.2523 0.2504
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0825 0.5
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0825 0.5
Schistosoma mansoni survival motor neuron protein 0.0047 0.1088 0.1066
Brugia malayi Nuclear hormone receptor E75 0.0049 0.1136 0.1965
Loa Loa (eye worm) hypothetical protein 0.0008 0.01 0.0158
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0103 0.2523 0.4388
Schistosoma mansoni RAR-like nuclear receptor 0.0103 0.2523 0.2504
Loa Loa (eye worm) hypothetical protein 0.0008 0.01 0.0158
Echinococcus multilocularis g-protein coupled receptor 0.0008 0.01 0.0076
Brugia malayi Hypothetical tyrosinase-like protein C02C2.1 in chromosome III 0.0111 0.2732 0.4752
Brugia malayi GnHR receptor homolog 0.0008 0.01 0.0158
Echinococcus multilocularis rhodopsin orphan GPCR 0.0008 0.01 0.0076
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0008 0.01 0.0076
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0103 0.2523 0.4388
Echinococcus multilocularis neuropeptide FF receptor 2 0.0008 0.01 0.0076
Echinococcus multilocularis rhodopsin orphan GPCR 0.0008 0.01 0.0076
Echinococcus multilocularis rhodopsin orphan GPCR 0.0008 0.01 0.0076
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0009 0.0116 0.0092
Loa Loa (eye worm) hypothetical protein 0.0103 0.2523 0.4388
Loa Loa (eye worm) hypothetical protein 0.0008 0.01 0.0158
Brugia malayi Melatonin receptor type 1A 0.0008 0.01 0.0158
Loa Loa (eye worm) hypothetical protein 0.0049 0.1136 0.1965
Loa Loa (eye worm) hypothetical protein 0.0033 0.0739 0.1272
Brugia malayi nuclear receptor NHR-88 0.0049 0.1136 0.1965
Brugia malayi ShTK domain containing protein 0.0111 0.2732 0.4752
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0054 0.1284 0.1262
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0044 0.1027 0.1004
Echinococcus granulosus neuropeptide FF receptor 2 0.0008 0.01 0.0076
Schistosoma mansoni nuclear hormone receptor 0.0049 0.1136 0.1113
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0008 0.01 0.0076
Echinococcus granulosus rhodopsin orphan GPCR 0.0008 0.01 0.0076
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0048 0.1128 0.1952
Brugia malayi G protein-coupled receptor 0.0008 0.01 0.0158
Brugia malayi hypothetical protein 0.0008 0.01 0.0158
Loa Loa (eye worm) neuropeptide F receptor 0.0008 0.01 0.0158
Loa Loa (eye worm) hypothetical protein 0.0008 0.01 0.0158
Schistosoma mansoni opsin-like receptor 0.0008 0.01 0.0076
Loa Loa (eye worm) hypothetical protein 0.0049 0.1136 0.1965
Loa Loa (eye worm) hypothetical protein 0.0008 0.01 0.0158
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0606 0.1041
Echinococcus granulosus rhodopsin orphan GPCR 0.0008 0.01 0.0076
Loa Loa (eye worm) hypothetical protein 0.0103 0.2523 0.4388
Echinococcus granulosus rhodopsin orphan GPCR 0.0008 0.01 0.0076
Loa Loa (eye worm) hypothetical protein 0.0049 0.1136 0.1965
Brugia malayi hypothetical protein 0.0229 0.5738 1
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0047 0.1088 0.1883
Echinococcus granulosus g protein coupled receptor 0.0008 0.01 0.0076
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0049 0.1136 0.1965
Loa Loa (eye worm) hypothetical protein 0.0005 0.0025 0.0026
Schistosoma mansoni histamine h1 receptor 0.0008 0.01 0.0076
Echinococcus multilocularis fmrfamide receptor 0.0008 0.01 0.0076
Echinococcus multilocularis rhodopsin orphan GPCR 0.0008 0.01 0.0076
Schistosoma mansoni neuropeptide receptor 0.0008 0.01 0.0076
Echinococcus granulosus FTZ F1 alpha 0.0103 0.2523 0.2504
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0008 0.01 0.0076
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0103 0.2523 0.2504
Brugia malayi nuclear hormone receptor family member nhr-6 0.0049 0.1136 0.1965
Trichomonas vaginalis bromodomain-containing protein, putative 0.0041 0.095 1
Onchocerca volvulus 0.0111 0.2732 1
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.014 0.3477 0.3461
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0044 0.1027 0.1775
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0008 0.01 0.0076
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0103 0.2523 0.2504
Loa Loa (eye worm) hypothetical protein 0.0103 0.2523 0.4388
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0103 0.2523 0.4388
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0044 0.1027 0.1004
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0825 0.8606
Schistosoma mansoni hypothetical protein 0.0008 0.01 0.0076
Brugia malayi Bromodomain containing protein 0.0005 0.0025 0.0026
Loa Loa (eye worm) hypothetical protein 0.0008 0.01 0.0158
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0103 0.2523 0.4388
Echinococcus granulosus peptide allatostatin:somatostatin 0.0008 0.01 0.0076
Plasmodium falciparum histone acetyltransferase GCN5 0.0038 0.0862 0.5

Activities

Activity type Activity value Assay description Source Reference
IC50 (functional) > 480.1 uM Trypanocidal activity against epimastigote stage of Trypanosoma cruzi Y after 72 hrs by MTT assay ChEMBL. 23851115
IC50 (binding) = 2.62 umol/L Inhibition of mushroom tyrosinase diphenolase activity using L-DOPA as substrate preincubated for 30 mins followed by substrate addition measured for 1 min ChEMBL. 25686594
Inhibition (binding) = 25 % Inhibition of Trypanosoma cruzi cruzain expressed in Escherichia coli DH5-alpha using Bz-Phe-Arg-AMC as substrate at 10 uM preincubated for 5 mins followed by substrate addition measured for 5 mins by spectrofluorimetric analysis relative to control ChEMBL. 23851115

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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