Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | cahepsin L-like non-peptiedase homolog | 0.0066 | 0.0246 | 0.0246 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0171 | 0.1339 | 0.4515 |
Schistosoma mansoni | sodium/chloride dependent transporter | 0.017 | 0.1325 | 0.1325 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.022 | 0.1849 | 0.6235 |
Leishmania major | cathepsin L-like protease | 0.0325 | 0.2942 | 1 |
Onchocerca volvulus | 0.0325 | 0.2942 | 0.2764 | |
Brugia malayi | cathepsin B-like cysteine proteinase | 0.0327 | 0.2965 | 0.2965 |
Echinococcus granulosus | cathepsin l1 | 0.022 | 0.1849 | 0.1849 |
Schistosoma mansoni | prolyl oligopeptidase (S09 family) | 0.0253 | 0.2198 | 0.2198 |
Entamoeba histolytica | cysteine protease, putative | 0.0171 | 0.1339 | 0.4054 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.0246 | 0.0246 |
Entamoeba histolytica | cysteine protease, putative | 0.0171 | 0.1339 | 0.4054 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0171 | 0.1339 | 0.1339 |
Echinococcus multilocularis | cathepsin L | 0.0066 | 0.0246 | 0.0246 |
Schistosoma mansoni | cathepsin s | 0.0105 | 0.0645 | 0.0645 |
Brugia malayi | Sodium:neurotransmitter symporter family protein 1, putative | 0.017 | 0.1325 | 0.1325 |
Toxoplasma gondii | hypothetical protein | 0.017 | 0.1325 | 0.4004 |
Plasmodium vivax | unspecified product | 0.0171 | 0.1339 | 0.4551 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0171 | 0.1339 | 0.4054 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.022 | 0.1849 | 0.1849 |
Loa Loa (eye worm) | hypothetical protein | 0.017 | 0.1325 | 0.1325 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0325 | 0.2942 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0325 | 0.2942 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0325 | 0.2942 | 0.9921 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0325 | 0.2942 | 0.2942 |
Plasmodium vivax | vivapain-2 | 0.0325 | 0.2942 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0101 | 0.0605 | 0.0605 |
Leishmania major | prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative | 0.0253 | 0.2198 | 0.7471 |
Echinococcus granulosus | calpain A | 0.0119 | 0.0794 | 0.0794 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0325 | 0.2942 | 1 |
Echinococcus granulosus | serotonin transporter | 0.1 | 1 | 1 |
Leishmania major | cysteine peptidase A (CPA) | 0.0325 | 0.2942 | 1 |
Schistosoma mansoni | norepinephrine/norepinephrine transporter | 0.017 | 0.1325 | 0.1325 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0105 | 0.0645 | 0.2174 |
Entamoeba histolytica | cysteine proteinase 2 | 0.0171 | 0.1339 | 0.4054 |
Schistosoma mansoni | cathepsin C | 0.0066 | 0.0246 | 0.0246 |
Brugia malayi | cathepsin Z-like cysteine proteinase | 0.0066 | 0.0246 | 0.0246 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0327 | 0.2965 | 0.2965 |
Loa Loa (eye worm) | norepinephrine transporter | 0.1 | 1 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0325 | 0.2942 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.0246 | 0.0246 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0171 | 0.1339 | 0.4551 |
Loa Loa (eye worm) | hypothetical protein | 0.0325 | 0.2942 | 0.2942 |
Brugia malayi | calpain family protein 1 | 0.0114 | 0.074 | 0.074 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.0246 | 0.0246 |
Plasmodium vivax | serine-repeat antigen 4 (SERA), putative | 0.0066 | 0.0246 | 0.0836 |
Leishmania major | oligopeptidase B-like protein,serine peptidase, clan SC, family S9A-like protein | 0.0101 | 0.0604 | 0.2053 |
Brugia malayi | Sodium:neurotransmitter symporter family protein | 0.017 | 0.1325 | 0.1325 |
Brugia malayi | cathepsin L-like cysteine proteinase, identical | 0.0105 | 0.0645 | 0.0645 |
Brugia malayi | calpain family protein 1 | 0.0114 | 0.074 | 0.074 |
Brugia malayi | Sodium:neurotransmitter symporter family protein | 0.017 | 0.1325 | 0.1325 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.022 | 0.1849 | 0.5946 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0325 | 0.2942 | 1 |
Plasmodium vivax | dipeptidyl aminopeptidase 1, putative | 0.0066 | 0.0246 | 0.0836 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0325 | 0.2942 | 0.9921 |
Schistosoma mansoni | subfamily C1A unassigned peptidase (C01 family) | 0.0066 | 0.0246 | 0.0246 |
Loa Loa (eye worm) | hypothetical protein | 0.017 | 0.1325 | 0.1325 |
Onchocerca volvulus | 0.0325 | 0.2942 | 0.2764 | |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0325 | 0.2942 | 0.9921 |
Loa Loa (eye worm) | hypothetical protein | 0.017 | 0.1325 | 0.1325 |
Leishmania major | oligopeptidase b | 0.0101 | 0.0604 | 0.2053 |
Plasmodium vivax | serine-repeat antigen (SERA) | 0.0066 | 0.0246 | 0.0836 |
Echinococcus granulosus | cathepsin l1 | 0.0325 | 0.2942 | 0.2942 |
Trypanosoma brucei | serine peptidase, clan SC, family S9A-like protein | 0.0101 | 0.0604 | 0.2053 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0066 | 0.0246 | 0.0246 |
Loa Loa (eye worm) | hypothetical protein | 0.0114 | 0.074 | 0.074 |
Brugia malayi | Cathepsin L-like precursor | 0.0325 | 0.2942 | 0.2942 |
Entamoeba histolytica | cysteine protease, putative | 0.0171 | 0.1339 | 0.4054 |
Loa Loa (eye worm) | hypothetical protein | 0.022 | 0.1849 | 0.1849 |
Loa Loa (eye worm) | Sodium:neurotransmitter symporter family protein | 0.017 | 0.1325 | 0.1325 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0066 | 0.0246 | 0.0246 |
Toxoplasma gondii | prolyl endopeptidase | 0.0253 | 0.2198 | 0.724 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0325 | 0.2942 | 0.2942 |
Plasmodium vivax | serine-repeat antigen (SERA) | 0.0066 | 0.0246 | 0.0836 |
Loa Loa (eye worm) | hypothetical protein | 0.017 | 0.1325 | 0.1325 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0147 | 0.1087 | 0.312 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0066 | 0.0246 | 0.0246 |
Giardia lamblia | Cathepsin B precursor | 0.0147 | 0.1087 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0325 | 0.2942 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0325 | 0.2942 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0325 | 0.2942 | 0.2942 |
Loa Loa (eye worm) | hypothetical protein | 0.0105 | 0.0645 | 0.0645 |
Leishmania major | cathepsin L-like protease | 0.0325 | 0.2942 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0066 | 0.0246 | 0.0246 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0325 | 0.2942 | 1 |
Schistosoma mansoni | sodium-dependent neurotransmitter transporter | 0.017 | 0.1325 | 0.1325 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0171 | 0.1339 | 0.4515 |
Plasmodium vivax | serine-repeat antigen 2 (SERA) | 0.0066 | 0.0246 | 0.0836 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0325 | 0.2942 | 0.2942 |
Echinococcus granulosus | cathepsin b | 0.0327 | 0.2965 | 0.2965 |
Echinococcus multilocularis | sodium and chloride dependent glycine | 0.017 | 0.1325 | 0.1325 |
Plasmodium falciparum | amino acid transporter, putative | 0.017 | 0.1325 | 0.4004 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.0246 | 0.0246 |
Schistosoma mansoni | prolyl oligopeptidase (S09 family) | 0.0253 | 0.2198 | 0.2198 |
Loa Loa (eye worm) | Sodium:neurotransmitter symporter family protein | 0.017 | 0.1325 | 0.1325 |
Plasmodium vivax | amine transporter, putative | 0.017 | 0.1325 | 0.4505 |
Entamoeba histolytica | cysteine protease, putative | 0.0171 | 0.1339 | 0.4054 |
Echinococcus granulosus | family C2 unassigned peptidase C02 family | 0.0119 | 0.0794 | 0.0794 |
Schistosoma mansoni | norepinephrine/norepinephrine transporter | 0.1 | 1 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0066 | 0.0246 | 0.0246 |
Loa Loa (eye worm) | hypothetical protein | 0.1 | 1 | 1 |
Onchocerca volvulus | 0.022 | 0.1849 | 0.1643 | |
Loa Loa (eye worm) | hypothetical protein | 0.0105 | 0.0645 | 0.0645 |
Brugia malayi | cathepsin F-like cysteine proteinase | 0.0066 | 0.0246 | 0.0246 |
Echinococcus multilocularis | cathepsin b | 0.0327 | 0.2965 | 0.2965 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0325 | 0.2942 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0325 | 0.2942 | 0.9921 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0171 | 0.1339 | 0.1339 |
Plasmodium vivax | unspecified product | 0.0066 | 0.0246 | 0.0836 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0325 | 0.2942 | 0.2942 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0325 | 0.2942 | 1 |
Trypanosoma cruzi | oligopeptidase B-like protein, putative | 0.0101 | 0.0604 | 0.2037 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0325 | 0.2942 | 1 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0325 | 0.2942 | 0.2942 |
Echinococcus multilocularis | prolyl endopeptidase | 0.0253 | 0.2198 | 0.2198 |
Schistosoma mansoni | norepinephrine/norepinephrine transporter | 0.017 | 0.1325 | 0.1325 |
Echinococcus granulosus | cathepsin b | 0.0327 | 0.2965 | 0.2965 |
Echinococcus multilocularis | uncharacterized sodium dependent transporter | 0.017 | 0.1325 | 0.1325 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0325 | 0.2942 | 1 |
Plasmodium vivax | hypothetical protein, conserved | 0.017 | 0.1325 | 0.4505 |
Echinococcus granulosus | cathepsin L cysteine protease | 0.0171 | 0.1339 | 0.1339 |
Echinococcus multilocularis | calpain family protein 1, d | 0.0084 | 0.0427 | 0.0427 |
Onchocerca volvulus | 0.017 | 0.1325 | 0.1107 | |
Schistosoma mansoni | family C2 unassigned peptidase (C02 family) | 0.0114 | 0.074 | 0.074 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0325 | 0.2942 | 1 |
Plasmodium vivax | serine-repeat antigen (SERA), putative | 0.0066 | 0.0246 | 0.0836 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0325 | 0.2942 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0171 | 0.1339 | 0.4054 |
Plasmodium vivax | dipeptidyl aminopeptidase 2, putative | 0.0066 | 0.0246 | 0.0836 |
Brugia malayi | Cathepsin L-like precursor | 0.0325 | 0.2942 | 0.2942 |
Trypanosoma cruzi | oligopeptidase b | 0.0101 | 0.0604 | 0.2037 |
Entamoeba histolytica | cysteine protease, putative | 0.0171 | 0.1339 | 0.4054 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0171 | 0.1339 | 0.4054 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0325 | 0.2942 | 1 |
Toxoplasma gondii | Sodium:neurotransmitter symporter family protein | 0.017 | 0.1325 | 0.4004 |
Loa Loa (eye worm) | hypothetical protein | 0.017 | 0.1325 | 0.1325 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0325 | 0.2942 | 1 |
Brugia malayi | cathepsin L precursor | 0.0066 | 0.0246 | 0.0246 |
Onchocerca volvulus | Cathepsin L homolog | 0.0325 | 0.2942 | 0.2764 |
Mycobacterium leprae | PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) | 0.0101 | 0.0604 | 0.5 |
Plasmodium vivax | serine-repeat antigen 5 (SERA) | 0.0066 | 0.0246 | 0.0836 |
Trypanosoma cruzi | prolyl endopeptidase | 0.0253 | 0.2198 | 0.7412 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.0246 | 0.0246 |
Entamoeba histolytica | cysteine proteinase 1, putative | 0.0171 | 0.1339 | 0.4054 |
Leishmania major | cathepsin L-like protease | 0.0325 | 0.2942 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.0147 | 0.1087 | 1 |
Schistosoma mansoni | subfamily C1A unassigned peptidase (C01 family) | 0.0066 | 0.0246 | 0.0246 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0325 | 0.2942 | 1 |
Plasmodium vivax | dipeptidyl aminopeptidase 3, putative | 0.0066 | 0.0246 | 0.0836 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0171 | 0.1339 | 0.1339 |
Schistosoma mansoni | sodium-dependent neurotransmitter transporter | 0.017 | 0.1325 | 0.1325 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0325 | 0.2942 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.0147 | 0.1087 | 1 |
Plasmodium vivax | serine-repeat antigen 4 (SERA) | 0.0066 | 0.0246 | 0.0836 |
Onchocerca volvulus | 0.017 | 0.1325 | 0.1107 | |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0325 | 0.2942 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.0427 | 0.0427 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.022 | 0.1849 | 0.5946 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0325 | 0.2942 | 0.9921 |
Entamoeba histolytica | cysteine protease, putative | 0.0325 | 0.2942 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0105 | 0.0645 | 0.0645 |
Trypanosoma cruzi | cysteine protease, putative | 0.0171 | 0.1339 | 0.4515 |
Brugia malayi | fibroinase precursor | 0.0066 | 0.0246 | 0.0246 |
Echinococcus granulosus | sodium and chloride dependent glycine | 0.017 | 0.1325 | 0.1325 |
Onchocerca volvulus | Cathepsin L homolog | 0.0325 | 0.2942 | 0.2764 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.0327 | 0.2965 | 0.2965 |
Schistosoma mansoni | sodium/chloride dependent transporter | 0.1 | 1 | 1 |
Leishmania major | cathepsin L-like protease | 0.0325 | 0.2942 | 1 |
Echinococcus multilocularis | cathepsin L | 0.0171 | 0.1339 | 0.1339 |
Trypanosoma cruzi | oligopeptidase b | 0.0101 | 0.0604 | 0.2037 |
Loa Loa (eye worm) | serotonin transporter b | 0.1 | 1 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0325 | 0.2942 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0066 | 0.0246 | 0.0246 |
Plasmodium vivax | vivapain-2 | 0.0325 | 0.2942 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0325 | 0.2942 | 1 |
Echinococcus multilocularis | sodium and chloride dependent glycine | 0.017 | 0.1325 | 0.1325 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0325 | 0.2942 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 1 | 0.0171 | 0.1339 | 0.4054 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0325 | 0.2942 | 1 |
Brugia malayi | cathepsin F-like cysteine proteinase | 0.0105 | 0.0645 | 0.0645 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0325 | 0.2942 | 1 |
Loa Loa (eye worm) | cathepsin B | 0.0147 | 0.1087 | 0.1087 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0325 | 0.2942 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0171 | 0.1339 | 0.4054 |
Loa Loa (eye worm) | calpain family protein 1 | 0.0114 | 0.074 | 0.074 |
Echinococcus granulosus | cathepsin L | 0.0066 | 0.0246 | 0.0246 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0325 | 0.2942 | 0.2942 |
Brugia malayi | Sodium:neurotransmitter symporter family protein | 0.017 | 0.1325 | 0.1325 |
Mycobacterium tuberculosis | Probable protease II PtrBa [first part] (oligopeptidase B) | 0.0227 | 0.192 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0325 | 0.2942 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0171 | 0.1339 | 0.4054 |
Loa Loa (eye worm) | hypothetical protein | 0.0327 | 0.2965 | 0.2965 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.0246 | 0.0246 |
Schistosoma mansoni | cathepsin S (C01 family) | 0.0066 | 0.0246 | 0.0246 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0171 | 0.1339 | 0.4054 |
Onchocerca volvulus | 0.0071 | 0.0292 | 0.0047 | |
Brugia malayi | Cathepsin L-like precursor | 0.0325 | 0.2942 | 0.2942 |
Loa Loa (eye worm) | solute carrier family 6 member 4 | 0.1 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.022 | 0.1849 | 0.1849 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0066 | 0.0246 | 0.0246 |
Echinococcus granulosus | cysteine protease | 0.0171 | 0.1339 | 0.1339 |
Loa Loa (eye worm) | cysteine proteinase cathepsin Z | 0.0066 | 0.0246 | 0.0246 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.0147 | 0.1087 | 0.3695 |
Toxoplasma gondii | hypothetical protein | 0.017 | 0.1325 | 0.4004 |
Plasmodium falciparum | transporter, putative | 0.017 | 0.1325 | 0.4004 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0171 | 0.1339 | 0.1339 |
Onchocerca volvulus | 0.1 | 1 | 1 | |
Toxoplasma gondii | cathepsin B | 0.0147 | 0.1087 | 0.312 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0325 | 0.2942 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0327 | 0.2965 | 0.2965 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0325 | 0.2942 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.022 | 0.1849 | 0.1849 |
Schistosoma mansoni | family C2 unassigned peptidase (C02 family) | 0.0119 | 0.0794 | 0.0794 |
Plasmodium vivax | serine-repeat antigen (SERA), putative | 0.0066 | 0.0246 | 0.0836 |
Echinococcus granulosus | prolyl endopeptidase | 0.0253 | 0.2198 | 0.2198 |
Schistosoma mansoni | sodium/chloride dependent neurotransmitter transporter | 0.017 | 0.1325 | 0.1325 |
Echinococcus granulosus | sodium dependent neurotransmitter transporter | 0.017 | 0.1325 | 0.1325 |
Trypanosoma cruzi | cysteine peptidase (N-terminal), putative | 0.0171 | 0.1339 | 0.4515 |
Treponema pallidum | sodium- and chloride- dependent transporter | 0.1 | 1 | 0.5 |
Entamoeba histolytica | cysteine protease, putative | 0.0171 | 0.1339 | 0.4054 |
Brugia malayi | Cathepsin L-like precursor | 0.022 | 0.1849 | 0.1849 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0325 | 0.2942 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0325 | 0.2942 | 0.2942 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0066 | 0.0246 | 0.0829 |
Schistosoma mansoni | sodium/chloride dependent neurotransmitter transporter | 0.017 | 0.1325 | 0.1325 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0325 | 0.2942 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0171 | 0.1339 | 0.4551 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0066 | 0.0246 | 0.0246 |
Loa Loa (eye worm) | fibroinase | 0.0325 | 0.2942 | 0.2942 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0325 | 0.2942 | 0.2942 |
Loa Loa (eye worm) | hypothetical protein | 0.1 | 1 | 1 |
Schistosoma mansoni | dipeptidyl-peptidase I (C01 family) | 0.0066 | 0.0246 | 0.0246 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0325 | 0.2942 | 1 |
Brugia malayi | cathepsin Z-like cysteine proteinase | 0.0066 | 0.0246 | 0.0246 |
Toxoplasma gondii | Sodium:neurotransmitter symporter family protein | 0.017 | 0.1325 | 0.4004 |
Echinococcus granulosus | uncharacterized sodium dependent transporter | 0.017 | 0.1325 | 0.1325 |
Echinococcus multilocularis | sodium dependent neurotransmitter transporter | 0.017 | 0.1325 | 0.1325 |
Echinococcus multilocularis | cathepsin b | 0.0327 | 0.2965 | 0.2965 |
Schistosoma mansoni | cathepsin B (C01 family) | 0.0066 | 0.0246 | 0.0246 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0325 | 0.2942 | 1 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0147 | 0.1087 | 0.3665 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.022 | 0.1849 | 0.1849 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0105 | 0.0645 | 0.0645 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0325 | 0.2942 | 0.2942 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0171 | 0.1339 | 0.4054 |
Onchocerca volvulus | 0.0325 | 0.2942 | 0.2764 | |
Echinococcus multilocularis | family C2 unassigned peptidase (C02 family) | 0.0119 | 0.0794 | 0.0794 |
Leishmania major | cathepsin L-like protease | 0.0325 | 0.2942 | 1 |
Onchocerca volvulus | 0.0325 | 0.2942 | 0.2764 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0325 | 0.2942 | 1 |
Onchocerca volvulus | Cathepsin F homolog | 0.0325 | 0.2942 | 0.2764 |
Loa Loa (eye worm) | ctsf protein | 0.0325 | 0.2942 | 0.2942 |
Onchocerca volvulus | 0.0325 | 0.2942 | 0.2764 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0325 | 0.2942 | 1 |
Trypanosoma brucei | prolyl oligopeptidase, putative | 0.0101 | 0.0604 | 0.2053 |
Chlamydia trachomatis | Ssodium-dependent amino acid transporter | 0.017 | 0.1325 | 0.5 |
Onchocerca volvulus | 0.0325 | 0.2942 | 0.2764 | |
Loa Loa (eye worm) | hypothetical protein | 0.017 | 0.1325 | 0.1325 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0325 | 0.2942 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0105 | 0.0645 | 0.2174 |
Toxoplasma gondii | Sodium:neurotransmitter symporter family protein | 0.017 | 0.1325 | 0.4004 |
Loa Loa (eye worm) | cysteine protease | 0.0325 | 0.2942 | 0.2942 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0325 | 0.2942 | 0.2942 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0325 | 0.2942 | 1 |
Schistosoma mansoni | family C2 unassigned peptidase (C02 family) | 0.0119 | 0.0794 | 0.0794 |
Schistosoma mansoni | subfamily C1A non-peptidase homologue (C01 family) | 0.0066 | 0.0246 | 0.0246 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0066 | 0.0246 | 0.0246 |
Trypanosoma brucei | oligopeptidase b | 0.0101 | 0.0604 | 0.2053 |
Brugia malayi | Cathepsin L-like precursor | 0.0325 | 0.2942 | 0.2942 |
Plasmodium vivax | vivapain-3 | 0.0171 | 0.1339 | 0.4551 |
Trypanosoma cruzi | serine peptidase, clan SC, family S9A-like protein, putative | 0.0101 | 0.0604 | 0.2037 |
Schistosoma mansoni | sodium/chloride dependent neurotransmitter transporter | 0.017 | 0.1325 | 0.1325 |
Echinococcus granulosus | sodium:chloride dependent neurotransmitter | 0.017 | 0.1325 | 0.1325 |
Trypanosoma brucei | prolyl endopeptidase | 0.0253 | 0.2198 | 0.7471 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0066 | 0.0246 | 0.0246 |
Loa Loa (eye worm) | hypothetical protein | 0.0253 | 0.2198 | 0.2198 |
Schistosoma mansoni | sodium-dependent amino acid transporter | 0.017 | 0.1325 | 0.1325 |
Echinococcus multilocularis | cysteine protease | 0.0325 | 0.2942 | 0.2942 |
Onchocerca volvulus | 0.0325 | 0.2942 | 0.2764 | |
Leishmania major | cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like | 0.0147 | 0.1087 | 0.3695 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0325 | 0.2942 | 0.2942 |
Leishmania major | cathepsin L-like protease | 0.0325 | 0.2942 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0325 | 0.2942 | 1 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0327 | 0.2965 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0325 | 0.2942 | 1 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0066 | 0.0246 | 0.0829 |
Loa Loa (eye worm) | hypothetical protein | 0.022 | 0.1849 | 0.1849 |
Brugia malayi | prolyl oligopeptidase family protein | 0.0253 | 0.2198 | 0.2198 |
Plasmodium vivax | vivapain-1 | 0.0171 | 0.1339 | 0.4551 |
Echinococcus granulosus | sodium and chloride dependent glycine | 0.017 | 0.1325 | 0.1325 |
Echinococcus multilocularis | cysteine protease | 0.0325 | 0.2942 | 0.2942 |
Toxoplasma gondii | cathepsin CPL | 0.0325 | 0.2942 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0105 | 0.0645 | 0.0645 |
Loa Loa (eye worm) | hypothetical protein | 0.017 | 0.1325 | 0.1325 |
Mycobacterium ulcerans | protease II (oligopeptidase B), PtrB | 0.0101 | 0.0604 | 0.5 |
Echinococcus granulosus | uncharacterized sodium dependent transporter | 0.017 | 0.1325 | 0.1325 |
Schistosoma mansoni | sodium/chloride dependent transporter | 0.017 | 0.1325 | 0.1325 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0171 | 0.1339 | 0.4054 |
Entamoeba histolytica | cysteine protease, putative | 0.0171 | 0.1339 | 0.4054 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0325 | 0.2942 | 1 |
Plasmodium vivax | unspecified product | 0.0105 | 0.0645 | 0.2191 |
Brugia malayi | cathepsin L-like precursor | 0.022 | 0.1849 | 0.1849 |
Entamoeba histolytica | cysteine protease, putative | 0.0171 | 0.1339 | 0.4054 |
Echinococcus granulosus | cathepsin L | 0.0171 | 0.1339 | 0.1339 |
Loa Loa (eye worm) | calpain family protein 1 | 0.0084 | 0.0427 | 0.0427 |
Echinococcus multilocularis | calpain A | 0.0119 | 0.0794 | 0.0794 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.0292 | 0.0292 |
Entamoeba histolytica | cysteine protease, putative | 0.0171 | 0.1339 | 0.4054 |
Entamoeba histolytica | cysteine proteinase, putative | 0.022 | 0.1849 | 0.5946 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0171 | 0.1339 | 0.4515 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0171 | 0.1339 | 0.1339 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0147 | 0.1087 | 0.1087 |
Plasmodium vivax | serine-repeat antigen 3 (SERA) | 0.0066 | 0.0246 | 0.0836 |
Loa Loa (eye worm) | hypothetical protein | 0.1 | 1 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0325 | 0.2942 | 0.2942 |
Leishmania major | cathepsin L-like protease | 0.0325 | 0.2942 | 1 |
Echinococcus multilocularis | serotonin transporter | 0.1 | 1 | 1 |
Onchocerca volvulus | 0.017 | 0.1325 | 0.1107 | |
Schistosoma mansoni | sodium-dependent neurotransmitter transporter | 0.017 | 0.1325 | 0.1325 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0325 | 0.2942 | 1 |
Leishmania major | cathepsin L-like protease | 0.0325 | 0.2942 | 1 |
Brugia malayi | hypothetical protein | 0.017 | 0.1325 | 0.1325 |
Brugia malayi | cathepsin L-like cysteine proteinase | 0.0066 | 0.0246 | 0.0246 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0325 | 0.2942 | 1 |
Onchocerca volvulus | Prolyl endopeptidase homolog | 0.0253 | 0.2198 | 0.2001 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0327 | 0.2965 | 0.2965 |
Echinococcus multilocularis | sodium:chloride dependent neurotransmitter | 0.017 | 0.1325 | 0.1325 |
Entamoeba histolytica | cysteine protease, putative | 0.0171 | 0.1339 | 0.4054 |
Entamoeba histolytica | cysteine protease, putative | 0.0171 | 0.1339 | 0.4054 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Inhibition (binding) | > 90 % | Binding affinity to STAT3 SH2 domain (unknown origin) using 5-FAM-SpYLPQTV as probe assessed as inhibition of protein dimerization at 2 uM after 60 mins by fluorescence polarization assay relative to control | ChEMBL. | 23791367 |
Inhibition (binding) | = 96 % | Binding affinity to STAT3 SH2 domain (unknown origin) using 5-FAM-SpYLPQTV as probe assessed as inhibition of protein dimerization at 100 uM after 60 mins by fluorescence polarization assay relative to control | ChEMBL. | 23791367 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.