Detailed information for compound 1773666

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 193.203 | Formula: C9H11N3O2
  • H donors: 3 H acceptors: 3 LogP: 0.17 Rotable bonds: 0
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C1NCc2c(N1)nc(c(c2C)O)C
  • InChi: 1S/C9H11N3O2/c1-4-6-3-10-9(14)12-8(6)11-5(2)7(4)13/h13H,3H2,1-2H3,(H2,10,11,12,14)
  • InChiKey: XZTNTCYJBNABBM-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens myoglobin Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Echinococcus multilocularis expressed protein myoglobin 154 aa 138 aa 23.2 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0003 0.0048 0.1935
Onchocerca volvulus 0.001 0.0231 0.0371
Trichomonas vaginalis Harbinger-1_Harbinger/PIFA2 transposable element protein 0.0003 0.0048 0.0072
Brugia malayi Muscleblind-like protein 0.0145 0.3593 0.359
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 0.0003 0.0048 0.0044
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0003 0.0048 0.0565
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0003 0.0048 1
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0003 0.0048 0.0044
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 36 0.0003 0.0048 0.0044
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0003 0.0048 0.1935
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Brugia malayi Pre-SET motif family protein 0.0216 0.5367 0.5365
Schistosoma mansoni ubiquitin-specific peptidase 9X (C19 family) 0.0003 0.0048 0.0044
Trichomonas vaginalis ubiquitin specific protease, putative 0.0003 0.0048 0.0072
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase 2, putative 0.0003 0.0048 0.0589
Loa Loa (eye worm) hypothetical protein 0.0003 0.0048 0.0044
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0003 0.0048 1
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0003 0.0048 1
Onchocerca volvulus 0.001 0.0231 0.0371
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Trichomonas vaginalis set domain proteins, putative 0.0246 0.6112 1
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 22 0.0003 0.0048 0.0044
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0003 0.0048 1
Loa Loa (eye worm) hypothetical protein 0.0003 0.0048 0.0044
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase, putative 0.0003 0.0048 0.0589
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0003 0.0048 1
Brugia malayi hypothetical protein 0.0003 0.0048 0.0044
Trichomonas vaginalis conserved hypothetical protein 0.0003 0.0048 0.0072
Onchocerca volvulus Globin homolog 0.001 0.0231 0.0371
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Entamoeba histolytica hypothetical protein 0.0035 0.0847 1
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0003 0.0048 1
Loa Loa (eye worm) hypothetical protein 0.001 0.0231 0.0227
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0003 0.0048 0.0044
Onchocerca volvulus 0.0246 0.6112 1
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0003 0.0048 0.0565
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0003 0.0048 0.0565
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0003 0.0048 0.0589
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0003 0.0048 1
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 7 0.0003 0.0048 0.0044
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Echinococcus granulosus histone lysine methyltransferase setb 0.0031 0.0749 0.0745
Schistosoma mansoni ubiquitin-specific peptidase 14 (C19 family) 0.0003 0.0048 0.0044
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Trypanosoma cruzi Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative 0.0003 0.0048 1
Echinococcus granulosus Ubiquitin carboxyl terminal hydrolase 48 0.0003 0.0048 0.0044
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0003 0.0048 0.1935
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Giardia lamblia DUB-1 0.0003 0.0048 1
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0003 0.0048 0.0044
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Entamoeba histolytica hypothetical protein 0.0003 0.0048 0.0565
Loa Loa (eye worm) hypothetical protein 0.0003 0.0048 0.0044
Entamoeba histolytica hypothetical protein 0.0001 0.0004 0.0047
Brugia malayi hypothetical protein 0.001 0.0231 0.0227
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0003 0.0048 0.0565
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0003 0.0048 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0003 0.0048 1
Onchocerca volvulus 0.001 0.0231 0.0371
Entamoeba histolytica hypothetical protein 0.0035 0.0847 1
Trichomonas vaginalis ubiquitin specific protease, putative 0.0003 0.0048 0.0072
Trichomonas vaginalis Harbinger-1_Harbinger/PIFA2 transposable element protein 0.0003 0.0048 0.0072
Echinococcus multilocularis Ubiquitin carboxyl terminal hydrolase 48 0.0003 0.0048 0.0044
Schistosoma mansoni ubiquitin-specific peptidase 46 (C19 family) 0.0003 0.0048 0.0044
Entamoeba histolytica hypothetical protein 0.0001 0.0004 0.0047
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 14 0.0003 0.0048 1
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0003 0.0048 0.0589
Trichomonas vaginalis conserved hypothetical protein 0.0003 0.0048 0.0072
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0003 0.0048 0.0565
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 12 0.0003 0.0048 0.0044
Trichomonas vaginalis conserved hypothetical protein 0.0003 0.0048 0.0072
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Toxoplasma gondii UBA/TS-N domain-containing protein 0.0003 0.0048 0.0589
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Echinococcus multilocularis u4:u6.u5 tri snrnp associated protein 2 0.0003 0.0048 0.0044
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0003 0.0048 0.1935
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0003 0.0048 0.0565
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0003 0.0048 1
Trichomonas vaginalis conserved hypothetical protein 0.0003 0.0048 0.0072
Loa Loa (eye worm) hypothetical protein 0.0003 0.0048 0.0044
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Loa Loa (eye worm) hypothetical protein 0.0145 0.3593 0.359
Entamoeba histolytica hypothetical protein 0.0035 0.0847 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0003 0.0048 0.0044
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 7 0.0003 0.0048 0.0044
Brugia malayi hypothetical protein 0.001 0.0231 0.0227
Trypanosoma cruzi cysteine peptidase, Clan CA, family C19, putative 0.0003 0.0048 1
Trichomonas vaginalis conserved hypothetical protein 0.0003 0.0048 0.0072
Loa Loa (eye worm) ubiquitin specific peptidase 39 0.0003 0.0048 0.0044
Loa Loa (eye worm) globin family protein 0.001 0.0231 0.0227
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Trichomonas vaginalis conserved hypothetical protein 0.0003 0.0048 0.0072
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0003 0.0048 0.1935
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0003 0.0048 1
Echinococcus granulosus u4:u6.u5 tri snrnp associated protein 2 0.0003 0.0048 0.0044
Brugia malayi Hypothetical 22.2 kDa protein C28F5.2 in chromosome II, putative 0.001 0.0231 0.0227
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0031 0.0749 0.0745
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0003 0.0048 0.0044
Onchocerca volvulus 0.0031 0.0749 0.122
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0216 0.5367 0.5365
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0003 0.0048 0.0044
Schistosoma mansoni ubiquitin-specific peptidase 4 (C19 family) 0.0003 0.0048 0.0044
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0003 0.0048 0.0044
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.0847 0.0843
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0003 0.0048 0.0044
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Onchocerca volvulus 0.001 0.0231 0.0371
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0003 0.0048 0.0044
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 46 0.0003 0.0048 0.0044
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0003 0.0048 0.0044
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Trichomonas vaginalis conserved hypothetical protein 0.0003 0.0048 0.0072
Toxoplasma gondii ubiquitin-specific protease USP4 0.0003 0.0048 0.0589
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Schistosoma mansoni calpain-7 (C02 family) 0.0003 0.0048 0.0044
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0003 0.0048 1
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0003 0.0048 0.0589
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Loa Loa (eye worm) hypothetical protein 0.0003 0.0048 0.0044
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0003 0.0048 0.1935
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 4 0.0003 0.0048 0.0044
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0003 0.0048 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Schistosoma mansoni serine/threonine protein kinase 0.0402 1 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0003 0.0048 0.0565
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0003 0.0048 1
Echinococcus granulosus serine:threonine protein kinase TAO1 0.0402 1 1
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0003 0.0048 0.0044
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0003 0.0048 0.0044
Schistosoma mansoni ubiquitin-specific peptidase 24 (C19 family) 0.0003 0.0048 0.0044
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 4 0.0003 0.0048 0.0044
Plasmodium falciparum U4/U6.U5 tri-snRNP-associated protein 2, putative 0.0003 0.0048 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0749 0.0745
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0003 0.0048 0.1935
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Mycobacterium tuberculosis Probable monooxygenase 0.001 0.0231 0.5
Schistosoma mansoni ubiquitin carboxyl-terminal hydrolase of the cysteine proteinase fold 0.0003 0.0048 0.0044
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Echinococcus multilocularis ubiquitin specific protease 41 0.0003 0.0048 0.0044
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.0847 0.0843
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Plasmodium vivax hypothetical protein, conserved 0.0003 0.0048 0.0589
Loa Loa (eye worm) globin family protein 0.001 0.0231 0.0227
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 24 0.0003 0.0048 0.0044
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0003 0.0048 1
Brugia malayi hypothetical protein 0.001 0.0231 0.0227
Schistosoma mansoni hypothetical protein 0.001 0.0231 0.0227
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Trichomonas vaginalis conserved hypothetical protein 0.0003 0.0048 0.0072
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase family 2 protein 0.0003 0.0048 0.0589
Onchocerca volvulus 0.001 0.0231 0.0371
Trichomonas vaginalis conserved hypothetical protein 0.0003 0.0048 0.0072
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Trichomonas vaginalis conserved hypothetical protein 0.0003 0.0048 0.0072
Loa Loa (eye worm) hypothetical protein 0.001 0.0231 0.0227
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0003 0.0048 0.0565
Trichomonas vaginalis conserved hypothetical protein 0.0003 0.0048 0.0072
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Schistosoma mansoni ubiquitin-specific peptidase 7 (C19 family) 0.0003 0.0048 0.0044
Trichomonas vaginalis conserved hypothetical protein 0.0003 0.0048 0.0072
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 14 0.0003 0.0048 1
Brugia malayi ubiquitin specific protease 14 0.0003 0.0048 0.0044
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0003 0.0048 0.0565
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0003 0.0048 0.0565
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0003 0.0048 1
Trichomonas vaginalis Harbinger-1_Harbinger/PIFA2 transposable element protein 0.0003 0.0048 0.0072
Plasmodium vivax SET domain protein, putative 0.0031 0.0749 1
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 16 0.0003 0.0048 0.0044
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0003 0.0048 0.0589
Trypanosoma brucei cysteine peptidase, Clan CA, family C19, putative 0.0003 0.0048 1
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase 13, putative 0.0003 0.0048 0.0589
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase, putative 0.0003 0.0048 1
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0003 0.0048 0.0044
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0003 0.0048 1
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0003 0.0048 1
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase 5, putative 0.0003 0.0048 0.0565
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Loa Loa (eye worm) hypothetical protein 0.001 0.0231 0.0227
Echinococcus multilocularis ubiquitin specific peptidase 42 (C19 family) 0.0003 0.0048 0.0044
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase 1, putative 0.0003 0.0048 0.0589
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0003 0.0048 0.0044
Brugia malayi Globin family protein 0.001 0.0231 0.0227
Echinococcus multilocularis muscleblind protein 0.0145 0.3593 0.359
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0031 0.0749 0.0745
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 14 0.0003 0.0048 0.0044
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0003 0.0048 0.0565
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0003 0.0048 0.1935
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Onchocerca volvulus 0.0003 0.0048 0.0072
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0003 0.0048 0.0044
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Trypanosoma cruzi Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative 0.0003 0.0048 1
Schistosoma mansoni ubiquitin-specific peptidase 5 (C19 family) 0.0003 0.0048 0.0044
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase family 2, putative 0.0003 0.0048 0.0589
Loa Loa (eye worm) hypothetical protein 0.0003 0.0048 0.0044
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0003 0.0048 1
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0003 0.0048 0.1935
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.0402 1 1
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0003 0.0048 0.0565
Schistosoma mansoni ubiquitin-specific peptidase 10 (C19 family) 0.0003 0.0048 0.0044
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0003 0.0048 0.1935
Trypanosoma cruzi cysteine peptidase, Clan CA, family C19, putative 0.0003 0.0048 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Plasmodium falciparum ubiquitin specific protease, putative 0.0003 0.0048 1
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0003 0.0048 0.0044
Echinococcus granulosus ubiquitin specific protease 41 0.0003 0.0048 0.0044
Brugia malayi Pre-SET motif family protein 0.0031 0.0749 0.0745
Schistosoma mansoni ubiquitin-specific peptidase 9X (C19 family) 0.0003 0.0048 0.0044
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 23 0.0003 0.0048 0.0044
Entamoeba histolytica hypothetical protein 0.0001 0.0004 0.0047
Brugia malayi ubiquitin carboxyl-terminal hydrolase 46 0.0003 0.0048 0.0044
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0003 0.0048 1
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 20 0.0003 0.0048 0.0044
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0003 0.0048 1
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0003 0.0048 1
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0003 0.0048 0.0044
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0003 0.0048 1
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0003 0.0048 0.0589
Loa Loa (eye worm) hypothetical protein 0.001 0.0231 0.0227
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0003 0.0048 0.0044
Schistosoma mansoni calpain-7 (C02 family) 0.0003 0.0048 0.0044
Toxoplasma gondii hypothetical protein 0.0003 0.0048 0.0589
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Schistosoma mansoni ubiquitin-specific peptidase 48 (C19 family) 0.0003 0.0048 0.0044
Plasmodium vivax U4/U6.U5 tri-snRNP-associated protein 2, putative 0.0003 0.0048 0.0589
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Trichomonas vaginalis conserved hypothetical protein 0.0003 0.0048 0.0072
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Trypanosoma brucei Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative 0.0003 0.0048 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0003 0.0048 0.1935
Loa Loa (eye worm) hypothetical protein 0.001 0.0231 0.0227
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Echinococcus granulosus muscleblind protein 0.0145 0.3593 0.359
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0003 0.0048 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Schistosoma mansoni ubiquitin-specific peptidase 30 (C19 family) 0.0003 0.0048 0.0044
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 5 0.0003 0.0048 0.0044
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 12 0.0003 0.0048 0.0044
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase 13, putative 0.0003 0.0048 1
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0003 0.0048 0.0565
Schistosoma mansoni ubiquitin-specific peptidase 22 (C19 family) 0.0003 0.0048 0.0044
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 14 0.0003 0.0048 0.0044
Schistosoma mansoni ubiquitin-specific peptidase 16 (C19 family) 0.0003 0.0048 0.0044
Echinococcus multilocularis expressed protein 0.0003 0.0048 0.0044
Onchocerca volvulus 0.0003 0.0048 0.0072
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0003 0.0048 1
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0003 0.0048 0.0589
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0003 0.0048 0.0044
Loa Loa (eye worm) hypothetical protein 0.0003 0.0048 0.0044
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0003 0.0048 1
Loa Loa (eye worm) hypothetical protein 0.0003 0.0048 0.0044
Trichomonas vaginalis conserved hypothetical protein 0.0003 0.0048 0.0072
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Schistosoma mansoni family C19 unassigned peptidase (C19 family) 0.0003 0.0048 0.0044
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0003 0.0048 0.0565
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0003 0.0048 0.0565
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0003 0.0048 0.1935
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0003 0.0048 0.0044
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Schistosoma mansoni peptidase 0.0004 0.0072 0.0068
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Loa Loa (eye worm) hypothetical protein 0.0003 0.0048 0.0044
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 22 0.0003 0.0048 0.0044
Leishmania major ubiqitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0003 0.0048 0.1935
Schistosoma mansoni hypothetical protein 0.0035 0.0847 0.0843
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0003 0.0048 0.1935
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 24 0.0003 0.0048 0.0044
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0003 0.0048 1
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0003 0.0048 1
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0003 0.0048 0.0044
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0003 0.0048 0.0565
Trypanosoma cruzi cysteine peptidase, Clan CA, family C19, putative 0.0003 0.0048 1
Trichomonas vaginalis conserved hypothetical protein 0.0003 0.0048 0.0072
Echinococcus granulosus 5'partial|Ubiquitin carboxyl terminal hydrolase 48 0.0003 0.0048 0.0044
Schistosoma mansoni hypothetical protein 0.0003 0.0048 0.0044
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 4 0.0003 0.0048 0.0044
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0003 0.0048 0.0565
Echinococcus multilocularis muscleblind protein 1 0.0145 0.3593 0.359
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0003 0.0048 1
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0031 0.0749 1
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0003 0.0048 0.0044
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Loa Loa (eye worm) hypothetical protein 0.001 0.0231 0.0227
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Schistosoma mansoni globin X 0.001 0.0231 0.0227
Brugia malayi Globin family protein 0.001 0.0231 0.0227
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0031 0.0749 0.0745
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0003 0.0048 0.0589
Schistosoma mansoni myoglobin 1 0.001 0.0231 0.0227
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0003 0.0048 1
Onchocerca volvulus 0.0003 0.0048 0.0072
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase, putative 0.0003 0.0048 0.0565
Brugia malayi hypothetical protein 0.0035 0.0847 0.0843
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase 14 0.0003 0.0048 1
Entamoeba histolytica hypothetical protein, conserved 0.0001 0.0004 0.0047
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0003 0.0048 0.0044
Plasmodium vivax ubiquitin specific protease, putative 0.0003 0.0048 0.0589
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0003 0.0048 0.0044
Brugia malayi Serine/threonine-protein kinase SULU 0.0402 1 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Schistosoma mansoni ubiquitin-specific peptidase 44 (C19 family) 0.0003 0.0048 0.0044
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase 2, putative 0.0003 0.0048 1
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.0402 1 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 47 0.0003 0.0048 0.0044
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase, putative 0.0003 0.0048 0.0589
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.0847 0.0843
Trichomonas vaginalis conserved hypothetical protein 0.0003 0.0048 0.0072
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0003 0.0048 0.0589
Loa Loa (eye worm) hypothetical protein 0.0145 0.3593 0.359
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 47 0.0003 0.0048 0.0044
Trichomonas vaginalis conserved hypothetical protein 0.0003 0.0048 0.0072
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase 5, putative 0.0003 0.0048 0.0565
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 36 0.0003 0.0048 0.0044
Loa Loa (eye worm) hypothetical protein 0.0003 0.0048 0.0044
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0003 0.0048 0.0044
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0003 0.0048 0.0044
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0003 0.0048 0.0565
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.003 0.072 0.0717
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0003 0.0048 1
Loa Loa (eye worm) hypothetical protein 0.0003 0.0048 0.0044
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Toxoplasma gondii ubiquitin specific protease 39 isoform 2, putative 0.0003 0.0048 0.0589
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 4 0.0003 0.0048 0.0044
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 16 0.0003 0.0048 0.0044
Trichomonas vaginalis ubiquitin specific protease, putative 0.0003 0.0048 0.0072
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0003 0.0048 0.0044
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0003 0.0048 0.0044
Trichomonas vaginalis conserved hypothetical protein 0.0003 0.0048 0.0072
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0003 0.0048 1
Plasmodium falciparum ubiquitin specific protease, putative 0.0003 0.0048 1
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0003 0.0048 0.0589
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0003 0.0048 1
Brugia malayi hypothetical protein 0.001 0.0231 0.0227
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 4 0.0003 0.0048 0.0044
Leishmania major adenylate cyclase-like protein 0.001 0.0231 1
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0003 0.0048 0.0044
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0003 0.0048 0.0044
Schistosoma mansoni ubiquitin-specific peptidase 45 (C19 family) 0.0003 0.0048 0.0044
Trypanosoma brucei Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative 0.0003 0.0048 1
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0003 0.0048 0.1935
Giardia lamblia Hypothetical protein 0.0003 0.0048 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Chlamydia trachomatis hypothetical protein 0.0001 0.0004 0.5
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Loa Loa (eye worm) hypothetical protein 0.0003 0.0048 0.0044
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 0.0003 0.0048 0.0044
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0003 0.0048 1
Loa Loa (eye worm) hypothetical protein 0.0031 0.0749 0.0745
Trichomonas vaginalis conserved hypothetical protein 0.0003 0.0048 0.0072
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Echinococcus granulosus ubiquitin specific peptidase 30 (C19 family) 0.0003 0.0048 0.0044
Schistosoma mansoni ubiquitin-specific peptidase 42 (C19 family) 0.0003 0.0048 0.0044
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0003 0.0048 0.0589
Trichomonas vaginalis conserved hypothetical protein 0.0003 0.0048 0.0072
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 20 0.0003 0.0048 0.0044
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0003 0.0048 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0749 0.0745
Trichomonas vaginalis Harbinger-1_Harbinger/PIFA2 transposable element protein 0.0003 0.0048 0.0072
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 7 0.0003 0.0048 0.0044
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0003 0.0048 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Mycobacterium ulcerans monooxygenase 0.001 0.0231 0.5
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0001 0.0004 0.0047
Schistosoma mansoni family C19 non-peptidase homologue (C19 family) 0.0003 0.0048 0.0044
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0003 0.0048 0.0565
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0003 0.0048 1
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 7 0.0003 0.0048 0.0044
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0003 0.0048 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0749 0.0745
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0003 0.0048 0.0044
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0003 0.0048 0.1935
Loa Loa (eye worm) hypothetical protein 0.0003 0.0048 0.0044
Echinococcus granulosus ubiquitin specific peptidase c family 0.0003 0.0048 0.0044
Echinococcus multilocularis ubiquitin specific peptidase (c family) ubiquitin terminal hydrolase 0.0003 0.0048 0.0044
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 5 0.0003 0.0048 0.0044
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase, putative 0.0003 0.0048 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0003 0.0048 0.0072
Entamoeba histolytica hypothetical protein 0.0035 0.0847 1
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 4 0.0003 0.0048 0.0044
Brugia malayi Globin family protein 0.001 0.0231 0.0227

Activities

Activity type Activity value Assay description Source Reference
EC50 (ADMET) = 2965 uM Cytotoxicity against human HepG2 cells assessed as intracellular ATP level after 24 hrs by luciferase reporter gene assay ChEMBL. 24482730
IC50 (binding) = 2.3 uM Inhibition of myoglobin (unknown origin)-mediated arachidonic acid oxidation using [14C]AA as substrate after 3 hrs by GC/NICI/MS analysis ChEMBL. 24482730
IC50 (binding) = 1000 uM Inhibition of ovine COX1-mediated arachidonic acid oxidation using [14C]AA as substrate after 5 mins by GC/NICI/MS analysis ChEMBL. 24482730

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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