Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0087 | 0.0646 | 0.1791 |
Loa Loa (eye worm) | matrix metalloproteinase | 0.0097 | 0.0733 | 0.2031 |
Schistosoma mansoni | hypothetical protein | 0.0138 | 0.1092 | 0.1049 |
Onchocerca volvulus | 0.0508 | 0.4382 | 1 | |
Schistosoma mansoni | metallocarboxypeptidase D peptidase unit 2 (M14 family) | 0.0087 | 0.0646 | 0.0601 |
Trichomonas vaginalis | tubulin beta chain, putative | 0.002 | 0.0048 | 0.0646 |
Trypanosoma cruzi | metallo-peptidase, Clan MC, Family M14, putative | 0.0087 | 0.0646 | 1 |
Wolbachia endosymbiont of Brugia malayi | DNA polymerase I | 0.0024 | 0.0089 | 0.5 |
Trichomonas vaginalis | Clan MC, family M14, Zinc carboxypeptidase-like metallopeptidase | 0.0087 | 0.0646 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0142 | 0.1131 | 0.3136 |
Schistosoma mansoni | norepinephrine/norepinephrine transporter | 0.0024 | 0.0086 | 0.0037 |
Schistosoma mansoni | peptidase | 0.0087 | 0.0646 | 0.0601 |
Toxoplasma gondii | hypothetical protein | 0.0024 | 0.0086 | 0.0174 |
Onchocerca volvulus | Matrilysin homolog | 0.0097 | 0.0733 | 0.1506 |
Loa Loa (eye worm) | serotonin transporter b | 0.0142 | 0.1131 | 0.3136 |
Loa Loa (eye worm) | norepinephrine transporter | 0.0142 | 0.1131 | 0.3136 |
Toxoplasma gondii | flagellar/basal body protein | 0.0087 | 0.0646 | 0.2787 |
Echinococcus granulosus | subfamily M14A unassigned peptidase | 0.0508 | 0.4382 | 0.946 |
Schistosoma mansoni | peptidase | 0.0087 | 0.0646 | 0.0601 |
Plasmodium falciparum | alpha tubulin 2 | 0.002 | 0.0048 | 0.3758 |
Onchocerca volvulus | 0.0508 | 0.4382 | 1 | |
Schistosoma mansoni | norepinephrine/norepinephrine transporter | 0.0024 | 0.0086 | 0.0037 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0536 | 0.4629 | 1 |
Onchocerca volvulus | Subfamily M14A unassigned peptidase homolog | 0.0508 | 0.4382 | 1 |
Mycobacterium ulcerans | DNA polymerase I | 0.0024 | 0.0089 | 0.0964 |
Trypanosoma brucei | metallo-peptidase, Clan MC, Family M14, putative | 0.0087 | 0.0646 | 1 |
Trypanosoma brucei | alpha tubulin | 0.002 | 0.0048 | 0.0748 |
Onchocerca volvulus | 0.0508 | 0.4382 | 1 | |
Brugia malayi | Zinc carboxypeptidase family protein | 0.0087 | 0.0646 | 0.3308 |
Leishmania major | zinc carboxypeptidase, putative,metallo-peptidase, Clan MC, Family M14 | 0.0087 | 0.0646 | 1 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0027 | 0.0116 | 0.0321 |
Trichomonas vaginalis | tubulin beta chain, putative | 0.002 | 0.0048 | 0.0646 |
Schistosoma mansoni | microsomal glutathione s-transferase | 0.0262 | 0.2193 | 0.2155 |
Plasmodium falciparum | transporter, putative | 0.0024 | 0.0086 | 1 |
Brugia malayi | tubulin alpha-2 chain | 0.002 | 0.0048 | 0.0248 |
Loa Loa (eye worm) | hypothetical protein | 0.0142 | 0.1131 | 0.3136 |
Echinococcus granulosus | uncharacterized sodium dependent transporter | 0.0024 | 0.0086 | 0.0081 |
Schistosoma mansoni | sodium-dependent neurotransmitter transporter | 0.0024 | 0.0086 | 0.0037 |
Trichomonas vaginalis | tubulin beta chain, putative | 0.002 | 0.0048 | 0.0646 |
Brugia malayi | Matrixin family protein | 0.0097 | 0.0733 | 0.3751 |
Trypanosoma brucei | mitochondrial structure specific endonuclease I (SSE-1), putative | 0.0017 | 0.0026 | 0.0401 |
Leishmania major | alpha tubulin | 0.002 | 0.0048 | 0.0748 |
Leishmania major | alpha tubulin | 0.002 | 0.0048 | 0.0748 |
Leishmania major | zinc carboxypeptidase, putative,metallo-peptidase, Clan MC, Family M14 | 0.0087 | 0.0646 | 1 |
Trypanosoma brucei | alpha tubulin | 0.002 | 0.0048 | 0.0748 |
Trichomonas vaginalis | tubulin alpha-1 chain, putative | 0.002 | 0.0048 | 0.0646 |
Trichomonas vaginalis | tubulin beta chain, putative | 0.002 | 0.0048 | 0.0646 |
Echinococcus granulosus | sodium and chloride dependent glycine | 0.0024 | 0.0086 | 0.0081 |
Toxoplasma gondii | zinc carboxypeptidase superfamily protein | 0.0087 | 0.0646 | 0.2787 |
Schistosoma mansoni | sodium/chloride dependent neurotransmitter transporter | 0.0024 | 0.0086 | 0.0037 |
Onchocerca volvulus | 0.0087 | 0.0646 | 0.1304 | |
Onchocerca volvulus | Matrilysin homolog | 0.0215 | 0.1781 | 0.3946 |
Brugia malayi | Zinc carboxypeptidase family protein | 0.0087 | 0.0646 | 0.3308 |
Chlamydia trachomatis | DNA polymerase I | 0.0024 | 0.0089 | 1 |
Loa Loa (eye worm) | carboxylesterase | 0.0027 | 0.0116 | 0.0321 |
Loa Loa (eye worm) | hypothetical protein | 0.0097 | 0.0733 | 0.2031 |
Trichomonas vaginalis | Clan MC, family M14, Zinc carboxypeptidase-like metallopeptidase | 0.0087 | 0.0646 | 1 |
Treponema pallidum | sodium- and chloride- dependent transporter | 0.0142 | 0.1131 | 1 |
Leishmania major | mitochondrial structure specific endonuclease I (SSE-1), putative | 0.0017 | 0.0026 | 0.0401 |
Onchocerca volvulus | 0.0508 | 0.4382 | 1 | |
Leishmania major | alpha tubulin | 0.002 | 0.0048 | 0.0748 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0116 | 0.0321 |
Loa Loa (eye worm) | matrixin family protein | 0.0235 | 0.1953 | 0.5414 |
Schistosoma mansoni | sodium-dependent neurotransmitter transporter | 0.0024 | 0.0086 | 0.0037 |
Loa Loa (eye worm) | tubulin alpha 2 | 0.0015 | 0.0007 | 0.002 |
Echinococcus granulosus | Zinc carboxypeptidase family protein | 0.0087 | 0.0646 | 0.1305 |
Loa Loa (eye worm) | alpha-tubulin | 0.002 | 0.0048 | 0.0134 |
Brugia malayi | Matrixin family protein | 0.0235 | 0.1953 | 1 |
Trichomonas vaginalis | tubulin epsilon chain, putative | 0.002 | 0.0048 | 0.0646 |
Plasmodium falciparum | amino acid transporter, putative | 0.0024 | 0.0086 | 1 |
Brugia malayi | Matrixin family protein | 0.0097 | 0.0733 | 0.3751 |
Schistosoma mansoni | sodium/chloride dependent transporter | 0.0024 | 0.0086 | 0.0037 |
Loa Loa (eye worm) | zinc carboxypeptidase | 0.0087 | 0.0646 | 0.1791 |
Onchocerca volvulus | 0.0097 | 0.0733 | 0.1506 | |
Schistosoma mansoni | norepinephrine/norepinephrine transporter | 0.0142 | 0.1131 | 0.1088 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0536 | 0.4629 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0086 | 0.0237 |
Schistosoma mansoni | peptidase | 0.0087 | 0.0646 | 0.0601 |
Onchocerca volvulus | Matrix metalloproteinase homolog | 0.0215 | 0.1781 | 0.3946 |
Mycobacterium tuberculosis | Probable peptidoglycan hydrolase | 0.0118 | 0.092 | 1 |
Trichomonas vaginalis | tubulin beta chain, putative | 0.002 | 0.0048 | 0.0646 |
Loa Loa (eye worm) | Sodium:neurotransmitter symporter family protein | 0.0024 | 0.0086 | 0.0237 |
Loa Loa (eye worm) | matrixin family protein | 0.0215 | 0.1781 | 0.4936 |
Trichomonas vaginalis | Clan MC, family M14, Zinc carboxypeptidase-like metallopeptidase | 0.0087 | 0.0646 | 1 |
Trichomonas vaginalis | tubulin epsilon chain, putative | 0.002 | 0.0048 | 0.0646 |
Mycobacterium leprae | PROBABLE HYDROLASE | 0.0118 | 0.092 | 1 |
Schistosoma mansoni | subfamily M14A unassigned peptidase (M14 family) | 0.0508 | 0.4382 | 0.4355 |
Trypanosoma cruzi | mitochondrial structure specific endonuclease I (SSE-1), putative | 0.0017 | 0.0026 | 0.0401 |
Echinococcus multilocularis | acetylcholinesterase | 0.0027 | 0.0116 | 0.0147 |
Echinococcus granulosus | carboxylesterase 5A | 0.0027 | 0.0116 | 0.0147 |
Brugia malayi | Sodium:neurotransmitter symporter family protein | 0.0024 | 0.0086 | 0.0438 |
Echinococcus granulosus | acetylcholinesterase | 0.0027 | 0.0116 | 0.0147 |
Mycobacterium tuberculosis | Probable DNA polymerase I PolA | 0.0024 | 0.0089 | 0.0702 |
Giardia lamblia | Nuclear ATP/GTP-binding protein | 0.0087 | 0.0646 | 1 |
Trypanosoma brucei | Carboxypeptidase-like protein | 0.0087 | 0.0646 | 1 |
Giardia lamblia | Nuclear ATP/GTP-binding protein | 0.0087 | 0.0646 | 1 |
Entamoeba histolytica | tubulin alpha-1 chain | 0.002 | 0.0048 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0087 | 0.0646 | 0.1791 |
Giardia lamblia | Nuclear ATP/GTP-binding protein | 0.0087 | 0.0646 | 1 |
Toxoplasma gondii | Sodium:neurotransmitter symporter family protein | 0.0024 | 0.0086 | 0.0174 |
Trypanosoma brucei | metallo-peptidase, Clan MC, Family M14, putative | 0.0087 | 0.0646 | 1 |
Trypanosoma cruzi | mitochondrial structure specific endonuclease I (SSE-1), putative | 0.0017 | 0.0026 | 0.0401 |
Mycobacterium ulcerans | 5'-3' exonuclease | 0.0017 | 0.0026 | 0.0282 |
Schistosoma mansoni | protease m14 carboxypeptidase | 0.0087 | 0.0646 | 0.0601 |
Trichomonas vaginalis | Clan MC, family M14, Zinc carboxypeptidase-like metallopeptidase | 0.0087 | 0.0646 | 1 |
Trichomonas vaginalis | tubulin beta chain, putative | 0.002 | 0.0048 | 0.0646 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0116 | 0.0321 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0048 | 0.0134 |
Leishmania major | alpha tubulin | 0.002 | 0.0048 | 0.0748 |
Echinococcus multilocularis | 0.0087 | 0.0646 | 0.1305 | |
Trypanosoma cruzi | zinc carboxypeptidase, putative | 0.0087 | 0.0646 | 1 |
Loa Loa (eye worm) | solute carrier family 6 member 4 | 0.0142 | 0.1131 | 0.3136 |
Leishmania major | alpha tubulin | 0.002 | 0.0048 | 0.0748 |
Brugia malayi | Tubulin alpha chain | 0.002 | 0.0048 | 0.0248 |
Toxoplasma gondii | zinc carboxypeptidase superfamily protein | 0.0087 | 0.0646 | 0.2787 |
Trichomonas vaginalis | Clan MC, family M14, Zinc carboxypeptidase-like metallopeptidase | 0.0087 | 0.0646 | 1 |
Schistosoma mansoni | sodium/chloride dependent neurotransmitter transporter | 0.0024 | 0.0086 | 0.0037 |
Brugia malayi | Sodium:neurotransmitter symporter family protein | 0.0142 | 0.1131 | 0.5792 |
Loa Loa (eye worm) | hypothetical protein | 0.0087 | 0.0646 | 0.1791 |
Mycobacterium ulcerans | hydrolase | 0.0118 | 0.092 | 1 |
Toxoplasma gondii | Sodium:neurotransmitter symporter family protein | 0.0024 | 0.0086 | 0.0174 |
Leishmania major | alpha tubulin | 0.002 | 0.0048 | 0.0748 |
Loa Loa (eye worm) | hypothetical protein | 0.0087 | 0.0646 | 0.1791 |
Brugia malayi | Zinc carboxypeptidase family protein | 0.0087 | 0.0646 | 0.3308 |
Leishmania major | zinc carboxypeptidase, putative,metallo-peptidase, Clan MC, Family M14 | 0.0087 | 0.0646 | 1 |
Brugia malayi | Hemopexin family protein | 0.0138 | 0.1092 | 0.5593 |
Echinococcus granulosus | sodium and chloride dependent glycine | 0.0024 | 0.0086 | 0.0081 |
Echinococcus granulosus | sodium dependent neurotransmitter transporter | 0.0024 | 0.0086 | 0.0081 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0027 | 0.0116 | 0.0068 |
Brugia malayi | Carboxylesterase family protein | 0.0027 | 0.0116 | 0.0593 |
Trichomonas vaginalis | Clan MC, family M14, Zinc carboxypeptidase-like metallopeptidase | 0.0087 | 0.0646 | 1 |
Echinococcus granulosus | uncharacterized sodium dependent transporter | 0.0024 | 0.0086 | 0.0081 |
Brugia malayi | Zinc carboxypeptidase family protein | 0.0087 | 0.0646 | 0.3308 |
Echinococcus multilocularis | sodium:chloride dependent neurotransmitter | 0.0024 | 0.0086 | 0.0081 |
Loa Loa (eye worm) | zinc carboxypeptidase | 0.0087 | 0.0646 | 0.1791 |
Entamoeba histolytica | tubulin alpha chain, putative | 0.002 | 0.0048 | 0.5 |
Echinococcus multilocularis | sodium dependent neurotransmitter transporter | 0.0024 | 0.0086 | 0.0081 |
Loa Loa (eye worm) | hypothetical protein | 0.0087 | 0.0646 | 0.1791 |
Trichomonas vaginalis | Clan MC, family M14, Zinc carboxypeptidase-like metallopeptidase | 0.0087 | 0.0646 | 1 |
Plasmodium vivax | hypothetical protein, conserved | 0.0024 | 0.0086 | 0.0963 |
Toxoplasma gondii | MAPEG family protein | 0.0262 | 0.2193 | 1 |
Echinococcus multilocularis | acetylcholinesterase | 0.0027 | 0.0116 | 0.0147 |
Schistosoma mansoni | matrix metallopeptidase-7 (M10 family) | 0.0097 | 0.0733 | 0.0688 |
Toxoplasma gondii | zinc carboxypeptidase, putative | 0.0087 | 0.0646 | 0.2787 |
Toxoplasma gondii | Sodium:neurotransmitter symporter family protein | 0.0024 | 0.0086 | 0.0174 |
Schistosoma mansoni | sodium/chloride dependent transporter | 0.0142 | 0.1131 | 0.1088 |
Leishmania major | alpha tubulin | 0.002 | 0.0048 | 0.0748 |
Brugia malayi | Zinc carboxypeptidase family protein | 0.0087 | 0.0646 | 0.3308 |
Trypanosoma cruzi | alpha tubulin, putative | 0.002 | 0.0048 | 0.0748 |
Echinococcus multilocularis | subfamily M14A unassigned peptidase | 0.0508 | 0.4382 | 0.946 |
Onchocerca volvulus | 0.0087 | 0.0646 | 0.1304 | |
Brugia malayi | Tubulin alpha-2 chain | 0.002 | 0.0048 | 0.0248 |
Leishmania major | alpha tubulin | 0.002 | 0.0048 | 0.0748 |
Brugia malayi | Zinc carboxypeptidase family protein | 0.0087 | 0.0646 | 0.3308 |
Loa Loa (eye worm) | tubulin alpha chain | 0.002 | 0.0048 | 0.0134 |
Echinococcus granulosus | microsomal glutathione S transferase 3 | 0.0262 | 0.2193 | 0.4681 |
Brugia malayi | Tubulin alpha-2 chain | 0.002 | 0.0048 | 0.0248 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0086 | 0.0237 |
Loa Loa (eye worm) | hypothetical protein | 0.0097 | 0.0733 | 0.2031 |
Schistosoma mansoni | sodium-dependent neurotransmitter transporter | 0.0024 | 0.0086 | 0.0037 |
Loa Loa (eye worm) | tubulin alpha chain | 0.002 | 0.0048 | 0.0134 |
Loa Loa (eye worm) | zinc carboxypeptidase | 0.0087 | 0.0646 | 0.1791 |
Echinococcus granulosus | acetylcholinesterase | 0.0027 | 0.0116 | 0.0147 |
Loa Loa (eye worm) | tubulin alpha-2 chain | 0.002 | 0.0048 | 0.0134 |
Trichomonas vaginalis | Clan MC, family M14, Zinc carboxypeptidase-like metallopeptidase | 0.0087 | 0.0646 | 1 |
Plasmodium vivax | tubulin alpha chain, putative | 0.002 | 0.0048 | 0.0362 |
Echinococcus multilocularis | sodium and chloride dependent glycine | 0.0024 | 0.0086 | 0.0081 |
Loa Loa (eye worm) | alpha-tubulin isotype 2 | 0.0015 | 0.0007 | 0.002 |
Onchocerca volvulus | 0.0142 | 0.1131 | 0.2434 | |
Leishmania major | alpha tubulin | 0.002 | 0.0048 | 0.0748 |
Loa Loa (eye worm) | tubulin alpha 2 | 0.0015 | 0.0007 | 0.002 |
Trypanosoma brucei | alpha tubulin | 0.002 | 0.0048 | 0.0748 |
Loa Loa (eye worm) | hypothetical protein | 0.0097 | 0.0733 | 0.2031 |
Trichomonas vaginalis | Clan MC, family M14, Zinc carboxypeptidase-like metallopeptidase | 0.0087 | 0.0646 | 1 |
Brugia malayi | Matrixin family protein | 0.0097 | 0.0733 | 0.3751 |
Brugia malayi | Matrix metalloprotease, N-terminal domain containing protein | 0.0118 | 0.092 | 0.4712 |
Brugia malayi | alpha-tubulin | 0.002 | 0.0048 | 0.0248 |
Echinococcus granulosus | cytosolic carboxypeptidase 1 | 0.0087 | 0.0646 | 0.1305 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0086 | 0.0237 |
Echinococcus multilocularis | sodium and chloride dependent glycine | 0.0024 | 0.0086 | 0.0081 |
Schistosoma mansoni | sodium/chloride dependent transporter | 0.0024 | 0.0086 | 0.0037 |
Echinococcus multilocularis | Zinc carboxypeptidase family protein | 0.0087 | 0.0646 | 0.1305 |
Trypanosoma cruzi | metallo-peptidase, Clan MC, Family M14, putative | 0.0087 | 0.0646 | 1 |
Schistosoma mansoni | family M14 non-peptidase homologue (M14 family) | 0.0087 | 0.0646 | 0.0601 |
Trypanosoma brucei | alpha tubulin | 0.002 | 0.0048 | 0.0748 |
Echinococcus granulosus | sodium:chloride dependent neurotransmitter | 0.0024 | 0.0086 | 0.0081 |
Onchocerca volvulus | Carboxypeptidase D homolog | 0.0087 | 0.0646 | 0.1304 |
Onchocerca volvulus | Cytosolic carboxypeptidase 1 homolog | 0.0087 | 0.0646 | 0.1304 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0086 | 0.0237 |
Brugia malayi | Zinc carboxypeptidase family protein | 0.0087 | 0.0646 | 0.3308 |
Loa Loa (eye worm) | hypothetical protein | 0.0421 | 0.3608 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0027 | 0.0116 | 0.0593 |
Onchocerca volvulus | 0.0138 | 0.1092 | 0.2343 | |
Plasmodium vivax | hypothetical protein, conserved | 0.0087 | 0.0646 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0086 | 0.0237 |
Loa Loa (eye worm) | hypothetical protein | 0.0087 | 0.0646 | 0.1791 |
Loa Loa (eye worm) | Sodium:neurotransmitter symporter family protein | 0.0024 | 0.0086 | 0.0237 |
Schistosoma mansoni | sodium/chloride dependent neurotransmitter transporter | 0.0024 | 0.0086 | 0.0037 |
Echinococcus granulosus | serotonin transporter | 0.0142 | 0.1131 | 0.2364 |
Loa Loa (eye worm) | hypothetical protein | 0.0087 | 0.0646 | 0.1791 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0086 | 0.0237 |
Schistosoma mansoni | hypothetical protein | 0.0087 | 0.0646 | 0.0601 |
Brugia malayi | Matrixin family protein | 0.0097 | 0.0733 | 0.3751 |
Plasmodium vivax | tubulin alpha chain, putative | 0.002 | 0.0048 | 0.0362 |
Loa Loa (eye worm) | hypothetical protein | 0.0087 | 0.0646 | 0.1791 |
Trypanosoma cruzi | metallo-peptidase, Clan MC, Family M14 | 0.0087 | 0.0646 | 1 |
Brugia malayi | Sodium:neurotransmitter symporter family protein | 0.0024 | 0.0086 | 0.0438 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0027 | 0.0116 | 0.0147 |
Echinococcus multilocularis | matrix metallopeptidase 7 (M10 family) | 0.0353 | 0.3002 | 0.6446 |
Brugia malayi | Sodium:neurotransmitter symporter family protein 1, putative | 0.0024 | 0.0086 | 0.0438 |
Loa Loa (eye worm) | alpha-tubulin | 0.002 | 0.0048 | 0.0134 |
Brugia malayi | Carboxypeptidase A2 precursor | 0.0087 | 0.0646 | 0.3308 |
Loa Loa (eye worm) | hypothetical protein | 0.0118 | 0.092 | 0.2551 |
Schistosoma mansoni | sodium-dependent amino acid transporter | 0.0024 | 0.0086 | 0.0037 |
Leishmania major | alpha tubulin | 0.002 | 0.0048 | 0.0748 |
Loa Loa (eye worm) | hypothetical protein | 0.0142 | 0.1131 | 0.3136 |
Loa Loa (eye worm) | zinc carboxypeptidase | 0.0087 | 0.0646 | 0.1791 |
Schistosoma mansoni | matrix metallopeptidase-9 (M10 family) | 0.008 | 0.0583 | 0.0537 |
Trypanosoma cruzi | Carboxypeptidase-like protein | 0.0087 | 0.0646 | 1 |
Echinococcus multilocularis | serotonin transporter | 0.0142 | 0.1131 | 0.2364 |
Echinococcus multilocularis | microsomal glutathione S transferase 3 | 0.0262 | 0.2193 | 0.4681 |
Brugia malayi | Zinc carboxypeptidase family protein | 0.0087 | 0.0646 | 0.3308 |
Echinococcus multilocularis | cytosolic carboxypeptidase protein 5 | 0.0087 | 0.0646 | 0.1305 |
Echinococcus granulosus | matrix metallopeptidase 7 M10 family | 0.0353 | 0.3002 | 0.6446 |
Schistosoma mansoni | carboxypeptidase N (M14 family) | 0.0087 | 0.0646 | 0.0601 |
Plasmodium falciparum | alpha tubulin 1 | 0.002 | 0.0048 | 0.3758 |
Trichomonas vaginalis | Clan MC, family M14, Zinc carboxypeptidase-like metallopeptidase | 0.0087 | 0.0646 | 1 |
Brugia malayi | Sodium:neurotransmitter symporter family protein | 0.0024 | 0.0086 | 0.0438 |
Loa Loa (eye worm) | hypothetical protein | 0.0087 | 0.0646 | 0.1791 |
Leishmania major | alpha tubulin | 0.002 | 0.0048 | 0.0748 |
Brugia malayi | tubulin alpha chain - mouse | 0.002 | 0.0048 | 0.0248 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0086 | 0.0237 |
Loa Loa (eye worm) | hypothetical protein | 0.0087 | 0.0646 | 0.1791 |
Plasmodium vivax | amine transporter, putative | 0.0024 | 0.0086 | 0.0963 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0007 | 0.002 |
Echinococcus granulosus | cytosolic carboxypeptidase protein 5 | 0.0087 | 0.0646 | 0.1305 |
Trichomonas vaginalis | Clan MC, family M14, Zinc carboxypeptidase-like metallopeptidase | 0.0087 | 0.0646 | 1 |
Echinococcus multilocularis | uncharacterized sodium dependent transporter | 0.0024 | 0.0086 | 0.0081 |
Leishmania major | alpha tubulin | 0.002 | 0.0048 | 0.0748 |
Brugia malayi | hypothetical protein | 0.0024 | 0.0086 | 0.0438 |
Toxoplasma gondii | hypothetical protein | 0.0024 | 0.0086 | 0.0174 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (functional) | = 290 uM | Inhibition of K+ loss from rabbit blood cells treated with [Ca2+] ionophore A-23,187. | ChEMBL. | 11563923 |
logP (ADMET) | = 4.93 | Partition coefficient (logP) | ChEMBL. | 11563923 |
logP (ADMET) | = 5.18 | Partition coefficient (logP) | ChEMBL. | 11563923 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.