Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | cathepsin L | 0.0293 | 0.0921 | 0.0921 |
Schistosoma mansoni | coup transcription factor | 0.0018 | 0.0027 | 0.0027 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0018 | 0.0027 | 0.0027 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0835 | 0.2684 | 0.2684 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1205 | 0.3886 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1205 | 0.3886 | 1 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0018 | 0.0027 | 0.0027 |
Toxoplasma gondii | cathepsin CPC2 | 0.0293 | 0.0921 | 0.2288 |
Loa Loa (eye worm) | Smad1 | 0.0014 | 0.0016 | 0.0016 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.001 | 0.0004 | 0.0004 |
Onchocerca volvulus | 0.0034 | 0.008 | 0.0136 | |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0018 | 0.0027 | 0.0027 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.001 | 0.0003 | 0.0003 |
Schistosoma mansoni | cathepsin S (C01 family) | 0.0293 | 0.0921 | 0.0921 |
Brugia malayi | cathepsin Z-like cysteine proteinase | 0.0293 | 0.0921 | 0.0921 |
Plasmodium vivax | unspecified product | 0.0663 | 0.2123 | 0.5414 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0663 | 0.2123 | 0.538 |
Brugia malayi | ecdysteroid receptor | 0.0018 | 0.0027 | 0.0027 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.1205 | 0.3886 | 0.3886 |
Brugia malayi | hypothetical protein | 0.0022 | 0.0042 | 0.0042 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0018 | 0.0027 | 0.0027 |
Brugia malayi | Smad1 | 0.0014 | 0.0016 | 0.0016 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0835 | 0.2684 | 0.5946 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0018 | 0.0027 | 0.0027 |
Schistosoma mansoni | subfamily C1A unassigned peptidase (C01 family) | 0.0293 | 0.0921 | 0.0921 |
Brugia malayi | Cathepsin L-like precursor | 0.1205 | 0.3886 | 0.3886 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1205 | 0.3886 | 1 |
Plasmodium falciparum | dipeptidyl aminopeptidase 1 | 0.0293 | 0.0921 | 0.2288 |
Brugia malayi | nuclear hormone receptor | 0.0018 | 0.0027 | 0.0027 |
Schistosoma mansoni | smad1 5 8 and | 0.0014 | 0.0016 | 0.0016 |
Plasmodium vivax | serine-repeat antigen 4 (SERA), putative | 0.0293 | 0.0921 | 0.2288 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0663 | 0.2123 | 0.209 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0018 | 0.0027 | 0.0027 |
Plasmodium falciparum | serine repeat antigen 6 | 0.0293 | 0.0921 | 0.2288 |
Entamoeba histolytica | cysteine protease, putative | 0.0293 | 0.0921 | 0.2231 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0018 | 0.0027 | 0.0027 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.1205 | 0.3886 | 0.386 |
Brugia malayi | MH2 domain containing protein | 0.0208 | 0.0645 | 0.0645 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1205 | 0.3886 | 1 |
Onchocerca volvulus | 0.1205 | 0.3886 | 1 | |
Schistosoma mansoni | subfamily C1A non-peptidase homologue (C01 family) | 0.0293 | 0.0921 | 0.0921 |
Brugia malayi | cathepsin F-like cysteine proteinase | 0.037 | 0.1172 | 0.1172 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0027 | 0.0059 | 0.0059 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.1205 | 0.3886 | 1 |
Schistosoma mansoni | hypothetical protein | 0.001 | 0.0002 | 0.0002 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0018 | 0.0027 | 0.0027 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1205 | 0.3886 | 1 |
Loa Loa (eye worm) | cysteine proteinase cathepsin Z | 0.0293 | 0.0921 | 0.0921 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0018 | 0.0027 | 0.0027 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0835 | 0.2684 | 0.685 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0293 | 0.0921 | 0.0921 |
Echinococcus granulosus | cpg binding protein | 0.0036 | 0.0086 | 0.0086 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0663 | 0.2123 | 0.538 |
Plasmodium falciparum | serine repeat antigen 9 | 0.0293 | 0.0921 | 0.2288 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.1205 | 0.3886 | 0.386 |
Brugia malayi | cathepsin L-like cysteine proteinase | 0.0293 | 0.0921 | 0.0921 |
Plasmodium vivax | serine-repeat antigen 4 (SERA) | 0.0293 | 0.0921 | 0.2288 |
Entamoeba histolytica | cysteine protease, putative | 0.0663 | 0.2123 | 0.538 |
Echinococcus granulosus | cathepsin b | 0.3087 | 1 | 1 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0018 | 0.0027 | 0.0027 |
Echinococcus granulosus | cathepsin b | 0.3087 | 1 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.1205 | 0.3886 | 1 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0072 | 0.0202 | 0.0202 |
Brugia malayi | Cathepsin L-like precursor | 0.1205 | 0.3886 | 0.3886 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1205 | 0.3886 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.1205 | 0.3886 | 0.3886 |
Entamoeba histolytica | papain family cysteine protease domain containing protein | 0.0293 | 0.0921 | 0.2231 |
Echinococcus granulosus | cathepsin l1 | 0.0835 | 0.2684 | 0.2684 |
Schistosoma mansoni | hypothetical protein | 0.0027 | 0.0059 | 0.0059 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1205 | 0.3886 | 1 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.1157 | 0.3729 | 0.3703 |
Schistosoma mansoni | Smad4 | 0.0014 | 0.0016 | 0.0016 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0018 | 0.0027 | 0.0027 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0018 | 0.0027 | 0.0027 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.1205 | 0.3886 | 0.386 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0087 | 0.0252 | 0.0252 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1205 | 0.3886 | 1 |
Brugia malayi | fibroinase precursor | 0.0293 | 0.0921 | 0.0921 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1205 | 0.3886 | 1 |
Plasmodium vivax | serine-repeat antigen 5 (SERA) | 0.0293 | 0.0921 | 0.2288 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.1205 | 0.3886 | 0.3886 |
Entamoeba histolytica | cysteine protease, putative | 0.0663 | 0.2123 | 0.538 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0018 | 0.0027 | 0.0027 |
Loa Loa (eye worm) | hypothetical protein | 0.0835 | 0.2684 | 0.2684 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0027 | 0.0027 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.1157 | 0.3729 | 0.3729 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0027 | 0.0059 | 0.0059 |
Plasmodium vivax | serine-repeat antigen (SERA) | 0.0293 | 0.0921 | 0.2288 |
Echinococcus multilocularis | cysteine protease | 0.1205 | 0.3886 | 0.3886 |
Plasmodium vivax | vivapain-3 | 0.0663 | 0.2123 | 0.5414 |
Entamoeba histolytica | cysteine protease, putative | 0.0663 | 0.2123 | 0.538 |
Echinococcus granulosus | cathepsin l1 | 0.1205 | 0.3886 | 0.3886 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0027 | 0.0027 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0087 | 0.0252 | 0.0252 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0663 | 0.2123 | 0.209 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0018 | 0.0027 | 0.0027 |
Entamoeba histolytica | cysteine protease, putative | 0.0663 | 0.2123 | 0.538 |
Echinococcus multilocularis | dnaJ subfamily B | 0.0481 | 0.1532 | 0.1532 |
Brugia malayi | CXXC zinc finger family protein | 0.0034 | 0.008 | 0.008 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0027 | 0.0027 |
Onchocerca volvulus | 0.0835 | 0.2684 | 0.6886 | |
Echinococcus multilocularis | cathepsin L | 0.0663 | 0.2123 | 0.2123 |
Schistosoma mansoni | thyroid hormone receptor | 0.0018 | 0.0027 | 0.0027 |
Loa Loa (eye worm) | hypothetical protein | 0.037 | 0.1172 | 0.1172 |
Echinococcus granulosus | geminin | 0.0146 | 0.0443 | 0.0443 |
Plasmodium falciparum | serine repeat antigen 4 | 0.0293 | 0.0921 | 0.2288 |
Plasmodium falciparum | dipeptidyl aminopeptidase 2 | 0.0293 | 0.0921 | 0.2288 |
Schistosoma mansoni | smad1 5 8 and | 0.0014 | 0.0016 | 0.0016 |
Schistosoma mansoni | cathepsin s | 0.037 | 0.1172 | 0.1172 |
Schistosoma mansoni | thyroid hormone receptor | 0.0018 | 0.0027 | 0.0027 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0663 | 0.2123 | 0.5414 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1205 | 0.3886 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0018 | 0.0027 | 0.0027 |
Onchocerca volvulus | 0.1205 | 0.3886 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0835 | 0.2684 | 0.5946 |
Loa Loa (eye worm) | hypothetical protein | 0.0293 | 0.0921 | 0.0921 |
Entamoeba histolytica | cysteine protease, putative | 0.0663 | 0.2123 | 0.538 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1205 | 0.3886 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.1205 | 0.3886 | 0.3886 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0018 | 0.0027 | 0.0027 |
Loa Loa (eye worm) | histone methyltransferase | 0.001 | 0.0004 | 0.0004 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0835 | 0.2684 | 0.2653 |
Loa Loa (eye worm) | hypothetical protein | 0.0087 | 0.0252 | 0.0252 |
Plasmodium vivax | dipeptidyl aminopeptidase 3, putative | 0.0293 | 0.0921 | 0.2288 |
Loa Loa (eye worm) | ctsf protein | 0.1205 | 0.3886 | 0.3886 |
Plasmodium vivax | vivapain-2 | 0.1205 | 0.3886 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.1157 | 0.3729 | 0.9472 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1205 | 0.3886 | 1 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.1205 | 0.3886 | 0.3886 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0018 | 0.0027 | 0.0027 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0027 | 0.0027 |
Brugia malayi | nuclear receptor NHR-88 | 0.0018 | 0.0027 | 0.0027 |
Schistosoma mansoni | hypothetical protein | 0.0027 | 0.0059 | 0.0059 |
Echinococcus multilocularis | Smad4 | 0.0014 | 0.0016 | 0.0016 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.001 | 0.0004 | 0.0004 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0027 | 0.0027 |
Schistosoma mansoni | neuropeptide receptor | 0.0216 | 0.0673 | 0.0673 |
Entamoeba histolytica | cysteine proteinase 2 | 0.0663 | 0.2123 | 0.538 |
Onchocerca volvulus | Cathepsin L homolog | 0.0293 | 0.0921 | 0.2318 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0014 | 0.0016 | 0.0016 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0663 | 0.2123 | 0.4054 |
Schistosoma mansoni | smad | 0.0014 | 0.0016 | 0.0016 |
Plasmodium vivax | vivapain-1 | 0.0663 | 0.2123 | 0.5414 |
Echinococcus granulosus | mothers against decapentaplegic 5 | 0.0014 | 0.0016 | 0.0016 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0018 | 0.0027 | 0.0027 |
Echinococcus multilocularis | cysteine protease | 0.1205 | 0.3886 | 0.3886 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0018 | 0.0027 | 0.0027 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0018 | 0.0027 | 0.0027 |
Entamoeba histolytica | cysteine protease, putative | 0.0293 | 0.0921 | 0.2231 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1205 | 0.3886 | 1 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0018 | 0.0027 | 0.0027 |
Plasmodium vivax | serine-repeat antigen 2 (SERA) | 0.0293 | 0.0921 | 0.2288 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.1205 | 0.3886 | 0.3886 |
Echinococcus granulosus | Smad4 | 0.0014 | 0.0016 | 0.0016 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.3087 | 1 | 1 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0018 | 0.0027 | 0.0027 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0018 | 0.0027 | 0.0027 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0018 | 0.0027 | 0.0027 |
Plasmodium falciparum | cysteine proteinase falcipain 1 | 0.0663 | 0.2123 | 0.5414 |
Echinococcus granulosus | Ataxin 2 N terminaldomain containing protein | 0.001 | 0.0002 | 0.0002 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0018 | 0.0027 | 0.0027 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0018 | 0.0027 | 0.0027 |
Leishmania major | cathepsin L-like protease | 0.1205 | 0.3886 | 1 |
Plasmodium falciparum | serine repeat antigen 3 | 0.0293 | 0.0921 | 0.2288 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.1205 | 0.3886 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.1157 | 0.3729 | 1 |
Toxoplasma gondii | cathepsin B | 0.1157 | 0.3729 | 0.9593 |
Brugia malayi | hypothetical protein | 0.0014 | 0.0016 | 0.0016 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0027 | 0.0059 | 0.0059 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0018 | 0.0027 | 0.0027 |
Entamoeba histolytica | cysteine proteinase, putative | 0.1205 | 0.3886 | 1 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0663 | 0.2123 | 0.2123 |
Plasmodium vivax | serine-repeat antigen (SERA), putative | 0.0293 | 0.0921 | 0.2288 |
Echinococcus multilocularis | Ataxin 2, N terminal,domain containing protein | 0.001 | 0.0002 | 0.0002 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0027 | 0.0059 | 0.0059 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0027 | 0.0059 | 0.0059 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1205 | 0.3886 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0059 | 0.0163 | 0.0163 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0059 | 0.0163 | 0.0163 |
Entamoeba histolytica | papain family cysteine protease domain containing protein | 0.0293 | 0.0921 | 0.2231 |
Echinococcus multilocularis | neuropeptide receptor | 0.0216 | 0.0673 | 0.0673 |
Plasmodium falciparum | serine repeat antigen 5 | 0.0293 | 0.0921 | 0.2288 |
Echinococcus multilocularis | geminin | 0.0146 | 0.0443 | 0.0443 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0018 | 0.0027 | 0.0027 |
Plasmodium falciparum | serine repeat antigen 1 | 0.0293 | 0.0921 | 0.2288 |
Brugia malayi | cathepsin Z-like cysteine proteinase | 0.0293 | 0.0921 | 0.0921 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0018 | 0.0027 | 0.0027 |
Schistosoma mansoni | hypothetical protein | 0.0146 | 0.0443 | 0.0443 |
Plasmodium falciparum | serine repeat antigen 8 | 0.0293 | 0.0921 | 0.2288 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0018 | 0.0027 | 0.0027 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0064 | 0.0178 | 0.0353 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0042 | 0.0042 |
Brugia malayi | cathepsin L-like cysteine proteinase, identical | 0.037 | 0.1172 | 0.1172 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1205 | 0.3886 | 1 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0018 | 0.0027 | 0.0027 |
Leishmania major | cathepsin L-like protease | 0.1205 | 0.3886 | 1 |
Plasmodium vivax | serine-repeat antigen (SERA) | 0.0293 | 0.0921 | 0.2288 |
Schistosoma mansoni | hypothetical protein | 0.0027 | 0.0059 | 0.0059 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0018 | 0.0027 | 0.0027 |
Leishmania major | cathepsin L-like protease | 0.1205 | 0.3886 | 1 |
Toxoplasma gondii | cathepsin CPC1 | 0.0293 | 0.0921 | 0.2288 |
Toxoplasma gondii | preprocathepsin c precursor, putative | 0.0293 | 0.0921 | 0.2288 |
Onchocerca volvulus | Cathepsin L homolog | 0.1205 | 0.3886 | 1 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0031 | 0.007 | 0.007 |
Brugia malayi | Cathepsin L-like precursor | 0.0835 | 0.2684 | 0.2684 |
Brugia malayi | MH1 domain containing protein | 0.0014 | 0.0016 | 0.0016 |
Loa Loa (eye worm) | hypothetical protein | 0.0835 | 0.2684 | 0.2684 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0018 | 0.0027 | 0.0027 |
Entamoeba histolytica | cysteine protease, putative | 0.0293 | 0.0921 | 0.2231 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1205 | 0.3886 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0059 | 0.0163 | 0.0163 |
Brugia malayi | cathepsin F-like cysteine proteinase | 0.0293 | 0.0921 | 0.0921 |
Onchocerca volvulus | 0.1205 | 0.3886 | 1 | |
Leishmania major | cathepsin L-like protease | 0.1205 | 0.3886 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.1205 | 0.3886 | 1 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.1205 | 0.3886 | 0.3886 |
Entamoeba histolytica | cysteine protease, putative | 0.1205 | 0.3886 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.1205 | 0.3886 | 0.3886 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1205 | 0.3886 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.1205 | 0.3886 | 0.3886 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0293 | 0.0921 | 0.0883 |
Echinococcus granulosus | neuropeptide receptor | 0.0216 | 0.0673 | 0.0673 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.1205 | 0.3886 | 0.386 |
Plasmodium falciparum | serine repeat antigen 2 | 0.0293 | 0.0921 | 0.2288 |
Loa Loa (eye worm) | hypothetical protein | 0.0293 | 0.0921 | 0.0921 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0293 | 0.0921 | 0.0921 |
Schistosoma mansoni | hypothetical protein | 0.0146 | 0.0443 | 0.0443 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0018 | 0.0027 | 0.0027 |
Loa Loa (eye worm) | fibroinase | 0.1205 | 0.3886 | 0.3886 |
Schistosoma mansoni | nuclear hormone receptor | 0.0018 | 0.0027 | 0.0027 |
Echinococcus granulosus | cysteine protease | 0.0663 | 0.2123 | 0.2123 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0663 | 0.2123 | 0.2123 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1205 | 0.3886 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.1205 | 0.3886 | 0.3886 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.1205 | 0.3886 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1205 | 0.3886 | 1 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.1157 | 0.3729 | 0.9593 |
Brugia malayi | MH2 domain containing protein | 0.0014 | 0.0016 | 0.0016 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0208 | 0.0645 | 0.0645 |
Entamoeba histolytica | cysteine protease, putative | 0.0293 | 0.0921 | 0.2231 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0018 | 0.0027 | 0.0027 |
Toxoplasma gondii | cathepsin CPL | 0.1205 | 0.3886 | 1 |
Leishmania major | cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like | 0.1157 | 0.3729 | 0.9593 |
Entamoeba histolytica | cysteine protease, putative | 0.0293 | 0.0921 | 0.2231 |
Loa Loa (eye worm) | hypothetical protein | 0.037 | 0.1172 | 0.1172 |
Brugia malayi | hypothetical protein | 0.0031 | 0.007 | 0.007 |
Brugia malayi | Cathepsin L-like precursor | 0.0835 | 0.2684 | 0.2684 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0663 | 0.2123 | 0.538 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0293 | 0.0921 | 0.0921 |
Loa Loa (eye worm) | hypothetical protein | 0.037 | 0.1172 | 0.1172 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.037 | 0.1172 | 0.1134 |
Loa Loa (eye worm) | hypothetical protein | 0.0293 | 0.0921 | 0.0921 |
Onchocerca volvulus | Cathepsin L homolog | 0.1205 | 0.3886 | 1 |
Leishmania major | cysteine peptidase A (CPA) | 0.1205 | 0.3886 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.3087 | 1 | 1 |
Echinococcus multilocularis | GPCR, family 2 | 0.0027 | 0.0059 | 0.0059 |
Echinococcus multilocularis | cathepsin b | 0.3087 | 1 | 1 |
Schistosoma mansoni | smad1 5 8 and | 0.0014 | 0.0016 | 0.0016 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0018 | 0.0027 | 0.0027 |
Echinococcus granulosus | FTZ F1 alpha | 0.0018 | 0.0027 | 0.0027 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0663 | 0.2123 | 0.5414 |
Echinococcus multilocularis | G protein coupled receptor 139 | 0.0216 | 0.0673 | 0.0673 |
Entamoeba histolytica | cysteine protease, putative | 0.0663 | 0.2123 | 0.538 |
Entamoeba histolytica | cysteine protease, putative | 0.0663 | 0.2123 | 0.538 |
Schistosoma mansoni | cpg binding protein | 0.0034 | 0.008 | 0.008 |
Echinococcus multilocularis | mothers against decapentaplegic 5 | 0.0014 | 0.0016 | 0.0016 |
Plasmodium vivax | dipeptidyl aminopeptidase 1, putative | 0.0293 | 0.0921 | 0.2288 |
Echinococcus multilocularis | cpg binding protein | 0.0036 | 0.0086 | 0.0086 |
Entamoeba histolytica | cysteine protease, putative | 0.0663 | 0.2123 | 0.538 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0663 | 0.2123 | 0.209 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0014 | 0.0016 | 0.0016 |
Brugia malayi | cathepsin L-like precursor | 0.0835 | 0.2684 | 0.2684 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0663 | 0.2123 | 0.2123 |
Entamoeba histolytica | cysteine protease, putative | 0.0663 | 0.2123 | 0.538 |
Plasmodium falciparum | serine repeat antigen 7 | 0.0293 | 0.0921 | 0.2288 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1205 | 0.3886 | 1 |
Onchocerca volvulus | 0.1205 | 0.3886 | 1 | |
Plasmodium vivax | vivapain-2 | 0.1205 | 0.3886 | 1 |
Schistosoma mansoni | TGF-beta signal transducer Smad2 | 0.0014 | 0.0016 | 0.0016 |
Loa Loa (eye worm) | hypothetical protein | 0.0293 | 0.0921 | 0.0921 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1205 | 0.3886 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0018 | 0.0027 | 0.0027 |
Onchocerca volvulus | 0.0293 | 0.0921 | 0.2318 | |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0018 | 0.0027 | 0.0027 |
Plasmodium vivax | unspecified product | 0.037 | 0.1172 | 0.2939 |
Echinococcus granulosus | cathepsin L | 0.0293 | 0.0921 | 0.0921 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1205 | 0.3886 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0663 | 0.2123 | 0.538 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.1205 | 0.3886 | 1 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.1205 | 0.3886 | 0.386 |
Leishmania major | cathepsin L-like protease | 0.1205 | 0.3886 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0293 | 0.0921 | 0.2231 |
Brugia malayi | Cathepsin L-like precursor | 0.1205 | 0.3886 | 0.3886 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0034 | 0.008 | 0.008 |
Loa Loa (eye worm) | hypothetical protein | 0.0293 | 0.0921 | 0.0921 |
Plasmodium vivax | unspecified product | 0.0293 | 0.0921 | 0.2288 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1205 | 0.3886 | 1 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0018 | 0.0027 | 0.0027 |
Giardia lamblia | Cathepsin B precursor | 0.1157 | 0.3729 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0027 | 0.0027 |
Brugia malayi | Cathepsin L-like precursor | 0.037 | 0.1172 | 0.1172 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0059 | 0.0059 |
Brugia malayi | cathepsin L precursor | 0.0293 | 0.0921 | 0.0921 |
Brugia malayi | MH1 domain containing protein | 0.0014 | 0.0016 | 0.0016 |
Loa Loa (eye worm) | cathepsin B | 0.1157 | 0.3729 | 0.3729 |
Entamoeba histolytica | cysteine protease, putative | 0.0663 | 0.2123 | 0.538 |
Schistosoma mansoni | cpg binding protein | 0.0036 | 0.0086 | 0.0086 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0018 | 0.0027 | 0.0027 |
Schistosoma mansoni | hypothetical protein | 0.0027 | 0.0059 | 0.0059 |
Onchocerca volvulus | Cathepsin F homolog | 0.1205 | 0.3886 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0293 | 0.0921 | 0.0921 |
Loa Loa (eye worm) | hypothetical protein | 0.0835 | 0.2684 | 0.2684 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0031 | 0.007 | 0.007 |
Plasmodium vivax | serine-repeat antigen (SERA), putative | 0.0293 | 0.0921 | 0.2288 |
Echinococcus granulosus | cathepsin L cysteine protease | 0.0663 | 0.2123 | 0.2123 |
Echinococcus granulosus | cathepsin L | 0.0663 | 0.2123 | 0.2123 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1205 | 0.3886 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1205 | 0.3886 | 1 |
Entamoeba histolytica | cysteine proteinase 1, putative | 0.0663 | 0.2123 | 0.538 |
Echinococcus granulosus | smad | 0.0014 | 0.0016 | 0.0016 |
Loa Loa (eye worm) | hypothetical protein | 0.0293 | 0.0921 | 0.0921 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.1205 | 0.3886 | 0.3886 |
Brugia malayi | Papain family cysteine protease containing protein | 0.1205 | 0.3886 | 0.3886 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0031 | 0.007 | 0.007 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.3087 | 1 | 1 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0087 | 0.0252 | 0.0252 |
Leishmania major | cathepsin L-like protease | 0.1205 | 0.3886 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1205 | 0.3886 | 1 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0018 | 0.0027 | 0.0027 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0208 | 0.0645 | 0.0645 |
Echinococcus granulosus | dnaJ subfamily B | 0.0481 | 0.1532 | 0.1532 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1205 | 0.3886 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0293 | 0.0921 | 0.0921 |
Loa Loa (eye worm) | hypothetical protein | 0.1205 | 0.3886 | 0.3886 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0293 | 0.0921 | 0.0921 |
Leishmania major | cathepsin L-like protease | 0.1205 | 0.3886 | 1 |
Schistosoma mansoni | cathepsin B (C01 family) | 0.0293 | 0.0921 | 0.0921 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0018 | 0.0027 | 0.0027 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0835 | 0.2684 | 0.2684 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0027 | 0.0059 | 0.0059 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1205 | 0.3886 | 1 |
Echinococcus multilocularis | TGF beta signal transducer SmadC | 0.0014 | 0.0016 | 0.0016 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0663 | 0.2123 | 0.2123 |
Plasmodium vivax | dipeptidyl aminopeptidase 2, putative | 0.0293 | 0.0921 | 0.2288 |
Loa Loa (eye worm) | cysteine protease | 0.1205 | 0.3886 | 0.3886 |
Trypanosoma cruzi | cysteine protease, putative | 0.0663 | 0.2123 | 0.209 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1205 | 0.3886 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0663 | 0.2123 | 0.538 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.037 | 0.1172 | 0.1172 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0293 | 0.0921 | 0.0921 |
Echinococcus multilocularis | cathepsin b | 0.3087 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0018 | 0.0027 | 0.0027 |
Leishmania major | cathepsin L-like protease | 0.1205 | 0.3886 | 1 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.3087 | 1 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0663 | 0.2123 | 0.538 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0663 | 0.2123 | 0.2123 |
Schistosoma mansoni | cpg binding protein | 0.0036 | 0.0086 | 0.0086 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0018 | 0.0027 | 0.0027 |
Echinococcus granulosus | GPCR family 2 | 0.0027 | 0.0059 | 0.0059 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0018 | 0.0027 | 0.0027 |
Schistosoma mansoni | subfamily C1A unassigned peptidase (C01 family) | 0.0293 | 0.0921 | 0.0921 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1205 | 0.3886 | 1 |
Plasmodium falciparum | dipeptidyl aminopeptidase 3 | 0.0293 | 0.0921 | 0.2288 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.037 | 0.1172 | 0.1134 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.3087 | 1 | 1 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0018 | 0.0027 | 0.0027 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0293 | 0.0921 | 0.0883 |
Schistosoma mansoni | hypothetical protein | 0.0481 | 0.1532 | 0.1532 |
Schistosoma mansoni | cathepsin C | 0.0293 | 0.0921 | 0.0921 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0018 | 0.0027 | 0.0027 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0027 | 0.0027 |
Schistosoma mansoni | dipeptidyl-peptidase I (C01 family) | 0.0293 | 0.0921 | 0.0921 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0293 | 0.0921 | 0.0921 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0663 | 0.2123 | 0.4054 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0027 | 0.0059 | 0.0059 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1205 | 0.3886 | 1 |
Brugia malayi | cahepsin L-like non-peptiedase homolog | 0.0293 | 0.0921 | 0.0921 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1205 | 0.3886 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0293 | 0.0921 | 0.2231 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0293 | 0.0921 | 0.0921 |
Echinococcus multilocularis | smad | 0.0014 | 0.0016 | 0.0016 |
Onchocerca volvulus | 0.1205 | 0.3886 | 1 | |
Onchocerca volvulus | 0.1205 | 0.3886 | 1 | |
Plasmodium vivax | serine-repeat antigen 3 (SERA) | 0.0293 | 0.0921 | 0.2288 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1205 | 0.3886 | 1 |
Echinococcus granulosus | TGF beta signal transducer SmadC | 0.0014 | 0.0016 | 0.0016 |
Entamoeba histolytica | cysteine protease, putative | 0.0663 | 0.2123 | 0.538 |
Brugia malayi | Cathepsin L-like precursor | 0.1205 | 0.3886 | 0.3886 |
Trypanosoma cruzi | cysteine peptidase (N-terminal), putative | 0.0663 | 0.2123 | 0.209 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0293 | 0.0921 | 0.0921 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0018 | 0.0027 | 0.0027 |
Brugia malayi | steroid hormone receptor | 0.0018 | 0.0027 | 0.0027 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.1205 | 0.3886 | 0.3886 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1205 | 0.3886 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0018 | 0.0027 | 0.0027 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.3087 | 1 | 1 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0018 | 0.0027 | 0.0027 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.007 | 0.007 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0027 | 0.0027 |
Giardia lamblia | Cathepsin B precursor | 0.1157 | 0.3729 | 1 |
Brugia malayi | MH2 domain containing protein | 0.0014 | 0.0016 | 0.0016 |
Onchocerca volvulus | 0.1205 | 0.3886 | 1 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
ED50 (functional) | = 18 mg kg-1 | Analgesic activity in sc dosed Swiss-Webster mouse assessed as reduction of acetylcholine-induced writhing | ChEMBL. | 31482 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.