Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | cathepsin Z-like cysteine proteinase | 0.0293 | 0.0921 | 0.0921 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0018 | 0.0027 | 0.0027 |
Plasmodium falciparum | serine repeat antigen 1 | 0.0293 | 0.0921 | 0.2288 |
Echinococcus multilocularis | geminin | 0.0146 | 0.0443 | 0.0443 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0018 | 0.0027 | 0.0027 |
Echinococcus multilocularis | neuropeptide receptor | 0.0216 | 0.0673 | 0.0673 |
Plasmodium falciparum | serine repeat antigen 5 | 0.0293 | 0.0921 | 0.2288 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0059 | 0.0163 | 0.0163 |
Entamoeba histolytica | papain family cysteine protease domain containing protein | 0.0293 | 0.0921 | 0.2231 |
Plasmodium vivax | serine-repeat antigen (SERA), putative | 0.0293 | 0.0921 | 0.2288 |
Echinococcus multilocularis | Ataxin 2, N terminal,domain containing protein | 0.001 | 0.0002 | 0.0002 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0027 | 0.0059 | 0.0059 |
Loa Loa (eye worm) | hypothetical protein | 0.0059 | 0.0163 | 0.0163 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1205 | 0.3886 | 1 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0027 | 0.0059 | 0.0059 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0018 | 0.0027 | 0.0027 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0663 | 0.2123 | 0.2123 |
Entamoeba histolytica | cysteine proteinase, putative | 0.1205 | 0.3886 | 1 |
Plasmodium falciparum | serine repeat antigen 3 | 0.0293 | 0.0921 | 0.2288 |
Giardia lamblia | Cathepsin B precursor | 0.1157 | 0.3729 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.1205 | 0.3886 | 1 |
Toxoplasma gondii | cathepsin B | 0.1157 | 0.3729 | 0.9593 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0027 | 0.0059 | 0.0059 |
Brugia malayi | hypothetical protein | 0.0014 | 0.0016 | 0.0016 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0018 | 0.0027 | 0.0027 |
Leishmania major | cathepsin L-like protease | 0.1205 | 0.3886 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 1 | 0.0663 | 0.2123 | 0.5414 |
Echinococcus granulosus | Ataxin 2 N terminaldomain containing protein | 0.001 | 0.0002 | 0.0002 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0018 | 0.0027 | 0.0027 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0018 | 0.0027 | 0.0027 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0018 | 0.0027 | 0.0027 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.3087 | 1 | 1 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0018 | 0.0027 | 0.0027 |
Echinococcus granulosus | Smad4 | 0.0014 | 0.0016 | 0.0016 |
Plasmodium vivax | serine-repeat antigen 2 (SERA) | 0.0293 | 0.0921 | 0.2288 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.1205 | 0.3886 | 0.3886 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0018 | 0.0027 | 0.0027 |
Entamoeba histolytica | cysteine protease, putative | 0.0293 | 0.0921 | 0.2231 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1205 | 0.3886 | 1 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0018 | 0.0027 | 0.0027 |
Echinococcus multilocularis | cysteine protease | 0.1205 | 0.3886 | 0.3886 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0018 | 0.0027 | 0.0027 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0018 | 0.0027 | 0.0027 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0663 | 0.2123 | 0.4054 |
Schistosoma mansoni | smad | 0.0014 | 0.0016 | 0.0016 |
Echinococcus granulosus | mothers against decapentaplegic 5 | 0.0014 | 0.0016 | 0.0016 |
Plasmodium vivax | vivapain-1 | 0.0663 | 0.2123 | 0.5414 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0014 | 0.0016 | 0.0016 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0027 | 0.0027 |
Schistosoma mansoni | neuropeptide receptor | 0.0216 | 0.0673 | 0.0673 |
Entamoeba histolytica | cysteine proteinase 2 | 0.0663 | 0.2123 | 0.538 |
Onchocerca volvulus | Cathepsin L homolog | 0.0293 | 0.0921 | 0.2318 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0018 | 0.0027 | 0.0027 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.1205 | 0.3886 | 0.3886 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0027 | 0.0027 |
Brugia malayi | nuclear receptor NHR-88 | 0.0018 | 0.0027 | 0.0027 |
Echinococcus multilocularis | Smad4 | 0.0014 | 0.0016 | 0.0016 |
Schistosoma mansoni | hypothetical protein | 0.0027 | 0.0059 | 0.0059 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.001 | 0.0004 | 0.0004 |
Plasmodium vivax | vivapain-2 | 0.1205 | 0.3886 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1205 | 0.3886 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.1157 | 0.3729 | 0.9472 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1205 | 0.3886 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.1205 | 0.3886 | 0.3886 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0018 | 0.0027 | 0.0027 |
Loa Loa (eye worm) | histone methyltransferase | 0.001 | 0.0004 | 0.0004 |
Loa Loa (eye worm) | hypothetical protein | 0.0087 | 0.0252 | 0.0252 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0835 | 0.2684 | 0.2653 |
Loa Loa (eye worm) | ctsf protein | 0.1205 | 0.3886 | 0.3886 |
Plasmodium vivax | dipeptidyl aminopeptidase 3, putative | 0.0293 | 0.0921 | 0.2288 |
Onchocerca volvulus | 0.1205 | 0.3886 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0835 | 0.2684 | 0.5946 |
Loa Loa (eye worm) | hypothetical protein | 0.0293 | 0.0921 | 0.0921 |
Entamoeba histolytica | cysteine protease, putative | 0.0663 | 0.2123 | 0.538 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0663 | 0.2123 | 0.5414 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0018 | 0.0027 | 0.0027 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1205 | 0.3886 | 1 |
Schistosoma mansoni | cathepsin s | 0.037 | 0.1172 | 0.1172 |
Schistosoma mansoni | thyroid hormone receptor | 0.0018 | 0.0027 | 0.0027 |
Schistosoma mansoni | smad1 5 8 and | 0.0014 | 0.0016 | 0.0016 |
Echinococcus granulosus | geminin | 0.0146 | 0.0443 | 0.0443 |
Plasmodium falciparum | serine repeat antigen 4 | 0.0293 | 0.0921 | 0.2288 |
Plasmodium falciparum | dipeptidyl aminopeptidase 2 | 0.0293 | 0.0921 | 0.2288 |
Schistosoma mansoni | thyroid hormone receptor | 0.0018 | 0.0027 | 0.0027 |
Loa Loa (eye worm) | hypothetical protein | 0.037 | 0.1172 | 0.1172 |
Onchocerca volvulus | 0.0835 | 0.2684 | 0.6886 | |
Echinococcus multilocularis | cathepsin L | 0.0663 | 0.2123 | 0.2123 |
Entamoeba histolytica | cysteine protease, putative | 0.0663 | 0.2123 | 0.538 |
Echinococcus multilocularis | dnaJ subfamily B | 0.0481 | 0.1532 | 0.1532 |
Brugia malayi | CXXC zinc finger family protein | 0.0034 | 0.008 | 0.008 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0027 | 0.0027 |
Echinococcus granulosus | cathepsin l1 | 0.1205 | 0.3886 | 0.3886 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0027 | 0.0027 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0087 | 0.0252 | 0.0252 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0663 | 0.2123 | 0.209 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0018 | 0.0027 | 0.0027 |
Plasmodium vivax | vivapain-3 | 0.0663 | 0.2123 | 0.5414 |
Entamoeba histolytica | cysteine protease, putative | 0.0663 | 0.2123 | 0.538 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0027 | 0.0059 | 0.0059 |
Plasmodium vivax | serine-repeat antigen (SERA) | 0.0293 | 0.0921 | 0.2288 |
Echinococcus multilocularis | cysteine protease | 0.1205 | 0.3886 | 0.3886 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.1157 | 0.3729 | 0.3729 |
Loa Loa (eye worm) | hypothetical protein | 0.0835 | 0.2684 | 0.2684 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0018 | 0.0027 | 0.0027 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0027 | 0.0027 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.1205 | 0.3886 | 0.3886 |
Entamoeba histolytica | cysteine protease, putative | 0.0663 | 0.2123 | 0.538 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1205 | 0.3886 | 1 |
Brugia malayi | fibroinase precursor | 0.0293 | 0.0921 | 0.0921 |
Plasmodium vivax | serine-repeat antigen 5 (SERA) | 0.0293 | 0.0921 | 0.2288 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0018 | 0.0027 | 0.0027 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.1205 | 0.3886 | 0.386 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0087 | 0.0252 | 0.0252 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1205 | 0.3886 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1205 | 0.3886 | 1 |
Schistosoma mansoni | Smad4 | 0.0014 | 0.0016 | 0.0016 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.1157 | 0.3729 | 0.3703 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0018 | 0.0027 | 0.0027 |
Brugia malayi | Cathepsin L-like precursor | 0.1205 | 0.3886 | 0.3886 |
Entamoeba histolytica | cysteine proteinase, putative | 0.1205 | 0.3886 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1205 | 0.3886 | 1 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0072 | 0.0202 | 0.0202 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.1205 | 0.3886 | 0.3886 |
Echinococcus granulosus | cathepsin l1 | 0.0835 | 0.2684 | 0.2684 |
Entamoeba histolytica | papain family cysteine protease domain containing protein | 0.0293 | 0.0921 | 0.2231 |
Schistosoma mansoni | hypothetical protein | 0.0027 | 0.0059 | 0.0059 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0018 | 0.0027 | 0.0027 |
Echinococcus granulosus | cathepsin b | 0.3087 | 1 | 1 |
Echinococcus granulosus | cathepsin b | 0.3087 | 1 | 1 |
Plasmodium vivax | serine-repeat antigen 4 (SERA) | 0.0293 | 0.0921 | 0.2288 |
Entamoeba histolytica | cysteine protease, putative | 0.0663 | 0.2123 | 0.538 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.1205 | 0.3886 | 0.386 |
Brugia malayi | cathepsin L-like cysteine proteinase | 0.0293 | 0.0921 | 0.0921 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0293 | 0.0921 | 0.0921 |
Plasmodium falciparum | serine repeat antigen 9 | 0.0293 | 0.0921 | 0.2288 |
Echinococcus granulosus | cpg binding protein | 0.0036 | 0.0086 | 0.0086 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0663 | 0.2123 | 0.538 |
Loa Loa (eye worm) | cysteine proteinase cathepsin Z | 0.0293 | 0.0921 | 0.0921 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0835 | 0.2684 | 0.685 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0018 | 0.0027 | 0.0027 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1205 | 0.3886 | 1 |
Schistosoma mansoni | hypothetical protein | 0.001 | 0.0002 | 0.0002 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0018 | 0.0027 | 0.0027 |
Schistosoma mansoni | subfamily C1A non-peptidase homologue (C01 family) | 0.0293 | 0.0921 | 0.0921 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0027 | 0.0059 | 0.0059 |
Brugia malayi | cathepsin F-like cysteine proteinase | 0.037 | 0.1172 | 0.1172 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.1205 | 0.3886 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1205 | 0.3886 | 1 |
Onchocerca volvulus | 0.1205 | 0.3886 | 1 | |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0018 | 0.0027 | 0.0027 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.1205 | 0.3886 | 0.386 |
Brugia malayi | MH2 domain containing protein | 0.0208 | 0.0645 | 0.0645 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0018 | 0.0027 | 0.0027 |
Plasmodium falciparum | serine repeat antigen 6 | 0.0293 | 0.0921 | 0.2288 |
Entamoeba histolytica | cysteine protease, putative | 0.0293 | 0.0921 | 0.2231 |
Schistosoma mansoni | smad1 5 8 and | 0.0014 | 0.0016 | 0.0016 |
Brugia malayi | nuclear hormone receptor | 0.0018 | 0.0027 | 0.0027 |
Plasmodium vivax | serine-repeat antigen 4 (SERA), putative | 0.0293 | 0.0921 | 0.2288 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0663 | 0.2123 | 0.209 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0835 | 0.2684 | 0.5946 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0018 | 0.0027 | 0.0027 |
Schistosoma mansoni | subfamily C1A unassigned peptidase (C01 family) | 0.0293 | 0.0921 | 0.0921 |
Brugia malayi | Cathepsin L-like precursor | 0.1205 | 0.3886 | 0.3886 |
Plasmodium falciparum | dipeptidyl aminopeptidase 1 | 0.0293 | 0.0921 | 0.2288 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1205 | 0.3886 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0018 | 0.0027 | 0.0027 |
Brugia malayi | Smad1 | 0.0014 | 0.0016 | 0.0016 |
Brugia malayi | hypothetical protein | 0.0022 | 0.0042 | 0.0042 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0663 | 0.2123 | 0.538 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.1205 | 0.3886 | 0.3886 |
Brugia malayi | ecdysteroid receptor | 0.0018 | 0.0027 | 0.0027 |
Brugia malayi | cathepsin Z-like cysteine proteinase | 0.0293 | 0.0921 | 0.0921 |
Plasmodium vivax | unspecified product | 0.0663 | 0.2123 | 0.5414 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.001 | 0.0004 | 0.0004 |
Onchocerca volvulus | 0.0034 | 0.008 | 0.0136 | |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0018 | 0.0027 | 0.0027 |
Schistosoma mansoni | cathepsin S (C01 family) | 0.0293 | 0.0921 | 0.0921 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.001 | 0.0003 | 0.0003 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1205 | 0.3886 | 1 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0018 | 0.0027 | 0.0027 |
Loa Loa (eye worm) | Smad1 | 0.0014 | 0.0016 | 0.0016 |
Toxoplasma gondii | cathepsin CPC2 | 0.0293 | 0.0921 | 0.2288 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0835 | 0.2684 | 0.2684 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1205 | 0.3886 | 1 |
Echinococcus multilocularis | cathepsin L | 0.0293 | 0.0921 | 0.0921 |
Schistosoma mansoni | coup transcription factor | 0.0018 | 0.0027 | 0.0027 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0018 | 0.0027 | 0.0027 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.3087 | 1 | 1 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0018 | 0.0027 | 0.0027 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.007 | 0.007 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0027 | 0.0027 |
Brugia malayi | MH2 domain containing protein | 0.0014 | 0.0016 | 0.0016 |
Onchocerca volvulus | 0.1205 | 0.3886 | 1 | |
Giardia lamblia | Cathepsin B precursor | 0.1157 | 0.3729 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1205 | 0.3886 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0018 | 0.0027 | 0.0027 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0293 | 0.0921 | 0.0921 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0018 | 0.0027 | 0.0027 |
Brugia malayi | steroid hormone receptor | 0.0018 | 0.0027 | 0.0027 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.1205 | 0.3886 | 0.3886 |
Brugia malayi | Cathepsin L-like precursor | 0.1205 | 0.3886 | 0.3886 |
Trypanosoma cruzi | cysteine peptidase (N-terminal), putative | 0.0663 | 0.2123 | 0.209 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1205 | 0.3886 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0663 | 0.2123 | 0.538 |
Echinococcus granulosus | TGF beta signal transducer SmadC | 0.0014 | 0.0016 | 0.0016 |
Onchocerca volvulus | 0.1205 | 0.3886 | 1 | |
Echinococcus multilocularis | smad | 0.0014 | 0.0016 | 0.0016 |
Onchocerca volvulus | 0.1205 | 0.3886 | 1 | |
Plasmodium vivax | serine-repeat antigen 3 (SERA) | 0.0293 | 0.0921 | 0.2288 |
Brugia malayi | cahepsin L-like non-peptiedase homolog | 0.0293 | 0.0921 | 0.0921 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1205 | 0.3886 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0293 | 0.0921 | 0.2231 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0293 | 0.0921 | 0.0921 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0027 | 0.0027 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0663 | 0.2123 | 0.4054 |
Schistosoma mansoni | dipeptidyl-peptidase I (C01 family) | 0.0293 | 0.0921 | 0.0921 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0293 | 0.0921 | 0.0921 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0027 | 0.0059 | 0.0059 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1205 | 0.3886 | 1 |
Plasmodium falciparum | dipeptidyl aminopeptidase 3 | 0.0293 | 0.0921 | 0.2288 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.037 | 0.1172 | 0.1134 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.3087 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0481 | 0.1532 | 0.1532 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0293 | 0.0921 | 0.0883 |
Schistosoma mansoni | cathepsin C | 0.0293 | 0.0921 | 0.0921 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0018 | 0.0027 | 0.0027 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0018 | 0.0027 | 0.0027 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0018 | 0.0027 | 0.0027 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1205 | 0.3886 | 1 |
Schistosoma mansoni | subfamily C1A unassigned peptidase (C01 family) | 0.0293 | 0.0921 | 0.0921 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0663 | 0.2123 | 0.2123 |
Schistosoma mansoni | cpg binding protein | 0.0036 | 0.0086 | 0.0086 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0018 | 0.0027 | 0.0027 |
Echinococcus granulosus | GPCR family 2 | 0.0027 | 0.0059 | 0.0059 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0018 | 0.0027 | 0.0027 |
Leishmania major | cathepsin L-like protease | 0.1205 | 0.3886 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0663 | 0.2123 | 0.538 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.3087 | 1 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0293 | 0.0921 | 0.0921 |
Echinococcus multilocularis | cathepsin b | 0.3087 | 1 | 1 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.037 | 0.1172 | 0.1172 |
Trypanosoma cruzi | cysteine protease, putative | 0.0663 | 0.2123 | 0.209 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1205 | 0.3886 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0663 | 0.2123 | 0.538 |
Echinococcus multilocularis | TGF beta signal transducer SmadC | 0.0014 | 0.0016 | 0.0016 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1205 | 0.3886 | 1 |
Plasmodium vivax | dipeptidyl aminopeptidase 2, putative | 0.0293 | 0.0921 | 0.2288 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0663 | 0.2123 | 0.2123 |
Loa Loa (eye worm) | cysteine protease | 0.1205 | 0.3886 | 0.3886 |
Schistosoma mansoni | cathepsin B (C01 family) | 0.0293 | 0.0921 | 0.0921 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0018 | 0.0027 | 0.0027 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0027 | 0.0059 | 0.0059 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0835 | 0.2684 | 0.2684 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0293 | 0.0921 | 0.0921 |
Leishmania major | cathepsin L-like protease | 0.1205 | 0.3886 | 1 |
Leishmania major | cathepsin L-like protease | 0.1205 | 0.3886 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1205 | 0.3886 | 1 |
Echinococcus granulosus | dnaJ subfamily B | 0.0481 | 0.1532 | 0.1532 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1205 | 0.3886 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0293 | 0.0921 | 0.0921 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0208 | 0.0645 | 0.0645 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0018 | 0.0027 | 0.0027 |
Loa Loa (eye worm) | hypothetical protein | 0.1205 | 0.3886 | 0.3886 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.3087 | 1 | 1 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0087 | 0.0252 | 0.0252 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.1205 | 0.3886 | 0.3886 |
Brugia malayi | Papain family cysteine protease containing protein | 0.1205 | 0.3886 | 0.3886 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0031 | 0.007 | 0.007 |
Loa Loa (eye worm) | hypothetical protein | 0.0293 | 0.0921 | 0.0921 |
Echinococcus granulosus | cathepsin L | 0.0663 | 0.2123 | 0.2123 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1205 | 0.3886 | 1 |
Entamoeba histolytica | cysteine proteinase 1, putative | 0.0663 | 0.2123 | 0.538 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1205 | 0.3886 | 1 |
Echinococcus granulosus | smad | 0.0014 | 0.0016 | 0.0016 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0031 | 0.007 | 0.007 |
Echinococcus granulosus | cathepsin L cysteine protease | 0.0663 | 0.2123 | 0.2123 |
Plasmodium vivax | serine-repeat antigen (SERA), putative | 0.0293 | 0.0921 | 0.2288 |
Loa Loa (eye worm) | hypothetical protein | 0.0835 | 0.2684 | 0.2684 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0018 | 0.0027 | 0.0027 |
Schistosoma mansoni | hypothetical protein | 0.0027 | 0.0059 | 0.0059 |
Onchocerca volvulus | Cathepsin F homolog | 0.1205 | 0.3886 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0293 | 0.0921 | 0.0921 |
Brugia malayi | MH1 domain containing protein | 0.0014 | 0.0016 | 0.0016 |
Loa Loa (eye worm) | cathepsin B | 0.1157 | 0.3729 | 0.3729 |
Entamoeba histolytica | cysteine protease, putative | 0.0663 | 0.2123 | 0.538 |
Schistosoma mansoni | cpg binding protein | 0.0036 | 0.0086 | 0.0086 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0059 | 0.0059 |
Brugia malayi | cathepsin L precursor | 0.0293 | 0.0921 | 0.0921 |
Loa Loa (eye worm) | hypothetical protein | 0.0293 | 0.0921 | 0.0921 |
Plasmodium vivax | unspecified product | 0.0293 | 0.0921 | 0.2288 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1205 | 0.3886 | 1 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0018 | 0.0027 | 0.0027 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0027 | 0.0027 |
Giardia lamblia | Cathepsin B precursor | 0.1157 | 0.3729 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.037 | 0.1172 | 0.1172 |
Leishmania major | cathepsin L-like protease | 0.1205 | 0.3886 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0293 | 0.0921 | 0.2231 |
Brugia malayi | Cathepsin L-like precursor | 0.1205 | 0.3886 | 0.3886 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0034 | 0.008 | 0.008 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0663 | 0.2123 | 0.538 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.1205 | 0.3886 | 0.386 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.1205 | 0.3886 | 1 |
Plasmodium vivax | unspecified product | 0.037 | 0.1172 | 0.2939 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1205 | 0.3886 | 1 |
Echinococcus granulosus | cathepsin L | 0.0293 | 0.0921 | 0.0921 |
Onchocerca volvulus | 0.0293 | 0.0921 | 0.2318 | |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0018 | 0.0027 | 0.0027 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1205 | 0.3886 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0018 | 0.0027 | 0.0027 |
Schistosoma mansoni | TGF-beta signal transducer Smad2 | 0.0014 | 0.0016 | 0.0016 |
Loa Loa (eye worm) | hypothetical protein | 0.0293 | 0.0921 | 0.0921 |
Onchocerca volvulus | 0.1205 | 0.3886 | 1 | |
Plasmodium vivax | vivapain-2 | 0.1205 | 0.3886 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1205 | 0.3886 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0663 | 0.2123 | 0.2123 |
Entamoeba histolytica | cysteine protease, putative | 0.0663 | 0.2123 | 0.538 |
Plasmodium falciparum | serine repeat antigen 7 | 0.0293 | 0.0921 | 0.2288 |
Brugia malayi | cathepsin L-like precursor | 0.0835 | 0.2684 | 0.2684 |
Plasmodium vivax | dipeptidyl aminopeptidase 1, putative | 0.0293 | 0.0921 | 0.2288 |
Echinococcus multilocularis | cpg binding protein | 0.0036 | 0.0086 | 0.0086 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0663 | 0.2123 | 0.209 |
Entamoeba histolytica | cysteine protease, putative | 0.0663 | 0.2123 | 0.538 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0014 | 0.0016 | 0.0016 |
Entamoeba histolytica | cysteine protease, putative | 0.0663 | 0.2123 | 0.538 |
Entamoeba histolytica | cysteine protease, putative | 0.0663 | 0.2123 | 0.538 |
Echinococcus multilocularis | mothers against decapentaplegic 5 | 0.0014 | 0.0016 | 0.0016 |
Schistosoma mansoni | cpg binding protein | 0.0034 | 0.008 | 0.008 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0663 | 0.2123 | 0.5414 |
Echinococcus multilocularis | G protein coupled receptor 139 | 0.0216 | 0.0673 | 0.0673 |
Echinococcus granulosus | FTZ F1 alpha | 0.0018 | 0.0027 | 0.0027 |
Echinococcus multilocularis | GPCR, family 2 | 0.0027 | 0.0059 | 0.0059 |
Schistosoma mansoni | smad1 5 8 and | 0.0014 | 0.0016 | 0.0016 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0018 | 0.0027 | 0.0027 |
Echinococcus multilocularis | cathepsin b | 0.3087 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0293 | 0.0921 | 0.0921 |
Onchocerca volvulus | Cathepsin L homolog | 0.1205 | 0.3886 | 1 |
Leishmania major | cysteine peptidase A (CPA) | 0.1205 | 0.3886 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.3087 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.037 | 0.1172 | 0.1172 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.037 | 0.1172 | 0.1134 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0293 | 0.0921 | 0.0921 |
Loa Loa (eye worm) | hypothetical protein | 0.037 | 0.1172 | 0.1172 |
Entamoeba histolytica | cysteine protease, putative | 0.0293 | 0.0921 | 0.2231 |
Brugia malayi | hypothetical protein | 0.0031 | 0.007 | 0.007 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0663 | 0.2123 | 0.538 |
Brugia malayi | Cathepsin L-like precursor | 0.0835 | 0.2684 | 0.2684 |
Brugia malayi | MH2 domain containing protein | 0.0014 | 0.0016 | 0.0016 |
Entamoeba histolytica | cysteine protease, putative | 0.0293 | 0.0921 | 0.2231 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0208 | 0.0645 | 0.0645 |
Leishmania major | cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like | 0.1157 | 0.3729 | 0.9593 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0018 | 0.0027 | 0.0027 |
Toxoplasma gondii | cathepsin CPL | 0.1205 | 0.3886 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1205 | 0.3886 | 1 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.1157 | 0.3729 | 0.9593 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1205 | 0.3886 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.1205 | 0.3886 | 0.3886 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.1205 | 0.3886 | 1 |
Loa Loa (eye worm) | fibroinase | 0.1205 | 0.3886 | 0.3886 |
Schistosoma mansoni | nuclear hormone receptor | 0.0018 | 0.0027 | 0.0027 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0663 | 0.2123 | 0.2123 |
Echinococcus granulosus | cysteine protease | 0.0663 | 0.2123 | 0.2123 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0018 | 0.0027 | 0.0027 |
Schistosoma mansoni | hypothetical protein | 0.0146 | 0.0443 | 0.0443 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0293 | 0.0921 | 0.0921 |
Loa Loa (eye worm) | hypothetical protein | 0.0293 | 0.0921 | 0.0921 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.1205 | 0.3886 | 0.386 |
Plasmodium falciparum | serine repeat antigen 2 | 0.0293 | 0.0921 | 0.2288 |
Brugia malayi | Cathepsin L-like precursor | 0.1205 | 0.3886 | 0.3886 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1205 | 0.3886 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.1205 | 0.3886 | 0.3886 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0293 | 0.0921 | 0.0883 |
Echinococcus granulosus | neuropeptide receptor | 0.0216 | 0.0673 | 0.0673 |
Entamoeba histolytica | cysteine protease, putative | 0.1205 | 0.3886 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.1205 | 0.3886 | 1 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.1205 | 0.3886 | 0.3886 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1205 | 0.3886 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0059 | 0.0163 | 0.0163 |
Brugia malayi | cathepsin F-like cysteine proteinase | 0.0293 | 0.0921 | 0.0921 |
Onchocerca volvulus | 0.1205 | 0.3886 | 1 | |
Leishmania major | cathepsin L-like protease | 0.1205 | 0.3886 | 1 |
Brugia malayi | MH1 domain containing protein | 0.0014 | 0.0016 | 0.0016 |
Loa Loa (eye worm) | hypothetical protein | 0.0835 | 0.2684 | 0.2684 |
Brugia malayi | Cathepsin L-like precursor | 0.0835 | 0.2684 | 0.2684 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0031 | 0.007 | 0.007 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0018 | 0.0027 | 0.0027 |
Entamoeba histolytica | cysteine protease, putative | 0.0293 | 0.0921 | 0.2231 |
Toxoplasma gondii | cathepsin CPC1 | 0.0293 | 0.0921 | 0.2288 |
Leishmania major | cathepsin L-like protease | 0.1205 | 0.3886 | 1 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0018 | 0.0027 | 0.0027 |
Toxoplasma gondii | preprocathepsin c precursor, putative | 0.0293 | 0.0921 | 0.2288 |
Onchocerca volvulus | Cathepsin L homolog | 0.1205 | 0.3886 | 1 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0018 | 0.0027 | 0.0027 |
Plasmodium vivax | serine-repeat antigen (SERA) | 0.0293 | 0.0921 | 0.2288 |
Leishmania major | cathepsin L-like protease | 0.1205 | 0.3886 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0027 | 0.0059 | 0.0059 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0018 | 0.0027 | 0.0027 |
Plasmodium falciparum | serine repeat antigen 8 | 0.0293 | 0.0921 | 0.2288 |
Schistosoma mansoni | hypothetical protein | 0.0146 | 0.0443 | 0.0443 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0042 | 0.0042 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0064 | 0.0178 | 0.0353 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1205 | 0.3886 | 1 |
Brugia malayi | cathepsin L-like cysteine proteinase, identical | 0.037 | 0.1172 | 0.1172 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
ED50 (functional) | = 3.4 mg kg-1 | Antiwrithing activity in sc dosed mouse assessed as prevention of acetylcholine-induced abdominal constriction response | ChEMBL. | 31481 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.