Detailed information for compound 1908037

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 310.428 | Formula: C18H30O4
  • H donors: 1 H acceptors: 2 LogP: 7.28 Rotable bonds: 14
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCCCCCCCCCCCOc1ccc(o1)C(=O)O
  • InChi: 1S/C18H30O4/c1-2-3-4-5-6-7-8-9-10-11-12-15-21-17-14-13-16(22-17)18(19)20/h13-14H,2-12,15H2,1H3,(H,19,20)
  • InChiKey: NWGMVYWMNJIIOJ-UHFFFAOYSA-N  

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0017 0.0332 0.0242
Trichomonas vaginalis DNA polymerase eta, putative 0.005 0.1852 0.4217
Loa Loa (eye worm) hypothetical protein 0.0017 0.0332 0.0241
Brugia malayi Troponin family protein 0.0117 0.5027 0.498
Loa Loa (eye worm) hypothetical protein 0.0017 0.0341 0.025
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0017 0.0341 0.025
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0012 0.0093 0.0112
Trypanosoma brucei DNA polymerase kappa, putative 0.005 0.1852 0.4102
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0607 0.0926
Trypanosoma brucei unspecified product 0.0042 0.1477 0.3232
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0104 0.4391 0.5327
Loa Loa (eye worm) hypothetical protein 0.0017 0.0332 0.0241
Echinococcus granulosus transcription factor Dp 1 0.0046 0.1689 0.205
Mycobacterium ulcerans DNA polymerase IV 0.005 0.1852 1
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0012 0.0093 0.0112
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0012 0.0093 0.0118
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0287 0.4013
Brugia malayi polk-prov protein 0.0038 0.1284 0.1203
Brugia malayi serine/threonine-protein kinase plk-2 0.0104 0.4391 0.4338
Schistosoma mansoni troponin I 0.0117 0.5027 0.6393
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0607 0.0926
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0012 0.0093 0.0112
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0017 0.0341 0.0413
Trypanosoma cruzi polo-like protein kinase, putative 0.0104 0.4391 1
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0017 0.0332 0.4633
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0012 0.0093 0.0118
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0023 0.0607 0.3277
Loa Loa (eye worm) hypothetical protein 0.0037 0.1276 0.1195
Entamoeba histolytica acetyltransferase, GNAT family 0.0047 0.1738 0.3451
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0012 0.0093 0.0118
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.008 0.3269 0.3966
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0287 0.4013
Echinococcus granulosus dna polymerase kappa 0.005 0.1852 0.2247
Loa Loa (eye worm) bromodomain containing protein 0.0022 0.0531 0.0443
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0607 0.0926
Trypanosoma brucei DNA polymerase kappa, putative 0.005 0.1852 0.4102
Trypanosoma brucei polo-like protein kinase 0.0104 0.4391 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.1284 0.2785
Onchocerca volvulus Troponin I homolog 0.0117 0.5027 0.7883
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0025 0.0716 0.1187
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0012 0.0093 0.0112
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0017 0.0332 0.0242
Schistosoma mansoni coup transcription factor 0.0012 0.0093 0.0118
Brugia malayi latrophilin 2 splice variant baaae 0.0037 0.1276 0.1195
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0012 0.0093 0.0112
Brugia malayi Calcitonin receptor-like protein seb-1 0.0055 0.209 0.2016
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0287 0.4013
Loa Loa (eye worm) hypothetical protein 0.0223 1 1
Onchocerca volvulus Serine\/threonine kinase homolog 0.0104 0.4391 0.6867
Brugia malayi hypothetical protein 0.0069 0.2786 0.2718
Brugia malayi Bromodomain containing protein 0.0077 0.3163 0.3099
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0012 0.0093 0.0112
Schistosoma mansoni steroid hormone receptor ad4bp 0.0012 0.0093 0.0118
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.008 0.3269 0.731
Schistosoma mansoni troponin I 0.0117 0.5027 0.6393
Mycobacterium ulcerans hypothetical protein 0.0023 0.0607 0.3277
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0023 0.0607 0.3277
Trypanosoma cruzi DNA polymerase kappa, putative 0.005 0.1852 0.3911
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0012 0.0093 0.0112
Schistosoma mansoni hypothetical protein 0.002 0.0466 0.0592
Echinococcus granulosus troponin i 0.0117 0.5027 0.6099
Trichomonas vaginalis CAMK family protein kinase 0.0051 0.193 0.4396
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0177 0.7863 1
Loa Loa (eye worm) troponin T 0.0069 0.2786 0.2718
Trypanosoma brucei DNA polymerase kappa, putative 0.005 0.1852 0.4102
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.008 0.3269 0.7231
Echinococcus granulosus methyl CpG binding domain protein 2 0.0017 0.0301 0.0365
Echinococcus multilocularis zinc finger protein 0.0023 0.0619 0.0751
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0025 0.0716 1
Echinococcus multilocularis GPCR, family 2 0.0017 0.0332 0.0403
Echinococcus multilocularis ecdysone induced protein 78C 0.0012 0.0093 0.0112
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.008 0.3269 0.4158
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.008 0.3269 0.731
Trypanosoma brucei DNA polymerase kappa, putative 0.005 0.1852 0.4102
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0104 0.4391 1
Schistosoma mansoni terminal deoxycytidyl transferase 0.0017 0.0341 0.0433
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0063 0.2461 0.2986
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0023 0.0607 0.8479
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0012 0.0093 0.0112
Trypanosoma brucei DNA polymerase kappa, putative 0.005 0.1852 0.4102
Trypanosoma brucei DNA polymerase eta, putative 0.0017 0.0341 0.0593
Schistosoma mansoni thyroid hormone receptor 0.0012 0.0093 0.0118
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0022 0.0553 0.0704
Trypanosoma brucei ISWI complex protein 0.0015 0.0221 0.0314
Loa Loa (eye worm) hypothetical protein 0.0046 0.1678 0.16
Trichomonas vaginalis bromodomain-containing protein, putative 0.0054 0.2049 0.4666
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0104 0.4391 0.5327
Loa Loa (eye worm) hypothetical protein 0.0037 0.128 0.1198
Schistosoma mansoni hypothetical protein 0.0015 0.0221 0.0281
Brugia malayi Troponin T 0.0069 0.2786 0.2718
Loa Loa (eye worm) hypothetical protein 0.0069 0.2786 0.2718
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0023 0.0607 0.3277
Brugia malayi acetyltransferase, GNAT family protein 0.0177 0.7863 0.7843
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0054 0.2049 1
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0607 0.0519
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0185 0.8242 1
Onchocerca volvulus Troponin T, skeletal muscle homolog 0.0069 0.2786 0.4303
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0607 0.0519
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0177 0.7863 0.954
Loa Loa (eye worm) hypothetical protein 0.0023 0.0607 0.0519
Schistosoma mansoni hypothetical protein 0.0017 0.0332 0.0422
Schistosoma mansoni RAR-like nuclear receptor 0.0012 0.0093 0.0118
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0607 0.0519
Echinococcus granulosus fetal alzheimer antigen falz 0.0022 0.0553 0.0671
Schistosoma mansoni troponin I 0.0117 0.5027 0.6393
Loa Loa (eye worm) hypothetical protein 0.0117 0.5027 0.498
Loa Loa (eye worm) PHD-finger family protein 0.002 0.0466 0.0376
Loa Loa (eye worm) hypothetical protein 0.0023 0.0607 0.0519
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.008 0.3269 0.3966
Brugia malayi Latrophilin receptor protein 2 0.0017 0.0332 0.0242
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0035 0.1168 0.1417
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.1284 0.2785
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0054 0.2049 1
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.046 0.0871
Schistosoma mansoni kinase 0.0053 0.1995 0.2537
Trypanosoma cruzi DNA polymerase eta, putative 0.0017 0.0341 0.0288
Loa Loa (eye worm) hypothetical protein 0.0023 0.0607 0.0519
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0607 0.3277
Mycobacterium tuberculosis Conserved hypothetical protein 0.0017 0.0341 0.4761
Loa Loa (eye worm) acetyltransferase 0.0177 0.7863 0.7843
Giardia lamblia Histone acetyltransferase GCN5 0.0047 0.1738 0.2783
Trichomonas vaginalis CAMK family protein kinase 0.0104 0.4391 1
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0104 0.4391 0.4338
Trypanosoma cruzi DNA polymerase kappa, putative 0.005 0.1852 0.3911
Schistosoma mansoni DNA polymerase eta 0.0017 0.0341 0.0433
Loa Loa (eye worm) troponin 0.0069 0.2786 0.2718
Echinococcus granulosus zinc finger protein 0.0023 0.0619 0.0751
Trypanosoma cruzi DNA polymerase kappa, putative 0.005 0.1852 0.3911
Giardia lamblia Kinase, PLK 0.0104 0.4391 1
Schistosoma mansoni hypothetical protein 0.0117 0.5027 0.6393
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0607 0.3277
Schistosoma mansoni hypothetical protein 0.0017 0.0332 0.0422
Trichomonas vaginalis CAMK family protein kinase 0.0051 0.193 0.4396
Loa Loa (eye worm) latrophilin receptor protein 2 0.0017 0.0332 0.0242
Leishmania major DNA polymerase kappa, putative 0.0025 0.0716 0.1187
Wolbachia endosymbiont of Brugia malayi bacterioferritin/cytochrome b1 0.001 0 0.5
Schistosoma mansoni zinc finger protein 0.0015 0.0221 0.0281
Loa Loa (eye worm) hypothetical protein 0.0044 0.159 0.1512
Brugia malayi PHD-finger family protein 0.0029 0.0864 0.0778
Echinococcus multilocularis FTZ F1 alpha 0.0012 0.0093 0.0112
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0012 0.0093 0.0112
Trichomonas vaginalis CAMK family protein kinase 0.0104 0.4391 1
Trypanosoma brucei DNA polymerase kappa, putative 0.005 0.1852 0.4102
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.0607 0.0657
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0012 0.0093 0.0112
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0023 0.0607 0.3277
Echinococcus multilocularis transcription factor Dp 1 0.0046 0.1689 0.205
Schistosoma mansoni hypothetical protein 0.0017 0.0332 0.0422
Schistosoma mansoni bromodomain containing protein 0.0066 0.2625 0.3339
Echinococcus multilocularis dna polymerase kappa 0.005 0.1852 0.2247
Loa Loa (eye worm) hypothetical protein 0.0069 0.2765 0.2697
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0017 0.0332 0.0403
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.005 0.1852 0.4217
Echinococcus granulosus histone lysine methyltransferase setb 0.0017 0.0301 0.0365
Brugia malayi ImpB/MucB/SamB family protein 0.0017 0.0341 0.025
Echinococcus granulosus histone acetyltransferase KAT2B 0.017 0.7523 0.9128
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0017 0.0301 0.0365
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.008 0.3269 0.3206
Echinococcus multilocularis thyroid hormone receptor alpha 0.0012 0.0093 0.0112
Trichomonas vaginalis CAMK family protein kinase 0.0104 0.4391 1
Loa Loa (eye worm) troponin I 0.0117 0.5027 0.498
Echinococcus granulosus dna polymerase eta 0.0017 0.0341 0.0413
Plasmodium falciparum histone acetyltransferase GCN5 0.0047 0.1738 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0017 0.0301 0.0383
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.008 0.3269 0.3206
Leishmania major DNA polymerase eta, putative 0.0017 0.0341 0.0288
Schistosoma mansoni hypothetical protein 0.0037 0.1276 0.1623
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0012 0.0093 0.0118
Brugia malayi Troponin T 0.0069 0.2786 0.2718
Echinococcus granulosus histone acetyltransferase KAT2B 0.0054 0.2049 0.2486
Trypanosoma brucei DNA polymerase kappa, putative 0.005 0.1852 0.4102
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.0607 0.0657
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.046 0.0871
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0607 0.3277
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0023 0.0607 0.8479
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0185 0.8242 1
Mycobacterium ulcerans DNA polymerase IV 0.005 0.1852 1
Brugia malayi ImpB/MucB/SamB family protein 0.0017 0.0341 0.025
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0023 0.0607 1
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0012 0.0093 0.0118
Brugia malayi Troponin T 0.0069 0.2786 0.2718
Echinococcus multilocularis oncosphere protein tso22e oncosphere protein tso22d oncosphere protein tso22c oncosphere protein tso22b oncosphere protein tso22 0.0145 0.6352 0.7706
Echinococcus granulosus ecdysone induced protein 78C 0.0012 0.0093 0.0112
Echinococcus multilocularis dna polymerase eta 0.0017 0.0341 0.0413
Schistosoma mansoni retinoic acid receptor RXR 0.0012 0.0093 0.0118
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.008 0.3269 0.731
Loa Loa (eye worm) hypothetical protein 0.0017 0.0332 0.0241
Trichomonas vaginalis CAMK family protein kinase 0.0104 0.4391 1
Entamoeba histolytica serine/threonine protein kinase, putative 0.0104 0.4391 1
Loa Loa (eye worm) hypothetical protein 0.0017 0.0301 0.0211
Trichomonas vaginalis CAMK family protein kinase 0.0104 0.4391 1
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0017 0.0341 0.0433
Onchocerca volvulus 0.0023 0.0607 0.0821
Entamoeba histolytica acyl-coA synthetase, putative 0.0023 0.0607 0.0657
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0301 0.0383
Trypanosoma brucei DNA polymerase IV, putative 0.005 0.1852 0.4102
Trichomonas vaginalis CAMK family protein kinase 0.0104 0.4391 1
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.046 0.0871
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0023 0.0607 1
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.008 0.3269 0.7395
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0017 0.0332 0.0403
Schistosoma mansoni zinc finger protein 0.0023 0.0619 0.0787
Schistosoma mansoni troponin I 0.0117 0.5027 0.6393
Trypanosoma brucei DNA polymerase kappa, putative 0.005 0.1852 0.4102
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0017 0.0301 0.0365
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0054 0.2049 0.4666
Loa Loa (eye worm) hypothetical protein 0.0017 0.0332 0.0241
Brugia malayi Bromodomain containing protein 0.0042 0.1478 0.1399
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0287 0.4013
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0012 0.0093 0.0112
Loa Loa (eye worm) hypothetical protein 0.0038 0.1284 0.1203
Schistosoma mansoni thyroid hormone receptor 0.0012 0.0093 0.0118
Treponema pallidum bacterioferrin (TpF1) 0.001 0 0.5
Schistosoma mansoni nuclear hormone receptor 0.0012 0.0093 0.0118
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0063 0.2461 0.2986
Echinococcus granulosus oncosphere protein Tso22e 0.0145 0.6352 0.7706
Echinococcus multilocularis troponin i 0.0117 0.5027 0.6099
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0017 0.0301 0.0383
Trypanosoma brucei DNA polymerase kappa, putative 0.005 0.1852 0.4102
Echinococcus granulosus FTZ F1 alpha 0.0012 0.0093 0.0112
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0055 0.209 0.2016
Schistosoma mansoni troponin t invertebrate 0.0145 0.6352 0.8078
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0054 0.2049 1
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0017 0.0341 0.0413
Trypanosoma brucei DNA polymerase IV, putative 0.0042 0.1477 0.3232
Echinococcus granulosus GPCR family 2 0.0017 0.0332 0.0403
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0022 0.0553 0.0671
Trypanosoma brucei DNA polymerase kappa, putative 0.0025 0.0716 0.1464
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0012 0.0093 0.0118
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0035 0.1168 0.1417
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0017 0.0332 0.1791
Brugia malayi Troponin I 0.0117 0.5027 0.498
Onchocerca volvulus Troponin T, skeletal muscle homolog 0.0145 0.6352 1
Trichomonas vaginalis CAMK family protein kinase 0.0104 0.4391 1
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0017 0.0332 0.5
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0301 0.0383
Schistosoma mansoni hypothetical protein 0.0017 0.0332 0.0422
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0012 0.0093 0.0112
Trypanosoma brucei DNA polymerase IV, putative 0.005 0.1852 0.4102
Loa Loa (eye worm) hypothetical protein 0.0117 0.5027 0.498
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0012 0.0093 0.0112
Trypanosoma cruzi DNA polymerase kappa, putative 0.005 0.1852 0.3911
Trypanosoma cruzi polo-like protein kinase, putative 0.0104 0.4391 1
Schistosoma mansoni serine/threonine protein kinase 0.0104 0.4391 0.5584
Loa Loa (eye worm) hypothetical protein 0.0017 0.0332 0.0241

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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