Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0012 | 0.0019 | 0.0019 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0012 | 0.0019 | 0.0019 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0012 | 0.0019 | 0.0019 |
Schistosoma mansoni | blooms syndrome DNA helicase | 0.0019 | 0.0116 | 0.0116 |
Plasmodium falciparum | type II NADH:ubiquinone oxidoreductase | 0.0074 | 0.0804 | 0.0804 |
Echinococcus multilocularis | peroxidasin | 0.009 | 0.1011 | 0.1011 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.1011 | 0.1011 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0012 | 0.0019 | 0.0019 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0265 | 0.3214 | 0.3214 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0012 | 0.0019 | 0.0019 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0278 | 0.3382 | 0.3357 |
Brugia malayi | NADPH:adrenodoxin oxidoreductase, mitochondrial precursor | 0.0074 | 0.0804 | 0.0804 |
Schistosoma mansoni | glutamate synthase | 0.0074 | 0.0804 | 0.0804 |
Entamoeba histolytica | glutamate synthase beta subunit, putative | 0.0074 | 0.0804 | 0.1849 |
Giardia lamblia | Glycerol-3-phosphate dehydrogenase | 0.0074 | 0.0804 | 0.2378 |
Echinococcus granulosus | glutamate synthase | 0.0074 | 0.0804 | 0.0804 |
Brugia malayi | Animal haem peroxidase family protein | 0.009 | 0.1011 | 0.1011 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0074 | 0.0804 | 0.077 |
Mycobacterium tuberculosis | Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase) | 0.0074 | 0.0804 | 0.0429 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0012 | 0.0019 | 0.0019 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0012 | 0.0019 | 0.0019 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0012 | 0.0019 | 0.0019 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0041 | 0.0392 | 0.0392 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0278 | 0.3382 | 1 |
Trichomonas vaginalis | glutamate synthase, putative | 0.0074 | 0.0804 | 0.2293 |
Mycobacterium ulcerans | NADPH:adrenodoxin oxidoreductase FprA | 0.0074 | 0.0804 | 0.1378 |
Schistosoma mansoni | coup transcription factor | 0.0012 | 0.0019 | 0.0019 |
Schistosoma mansoni | disulfide oxidoreductase | 0.0074 | 0.0804 | 0.0804 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase, LpdB | 0.0278 | 0.3382 | 1 |
Brugia malayi | ecdysteroid receptor | 0.0012 | 0.0019 | 0.0019 |
Mycobacterium tuberculosis | Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (ferredoxin-NADP(+) reductase) | 0.0074 | 0.0804 | 0.0429 |
Schistosoma mansoni | nuclear hormone receptor | 0.0012 | 0.0019 | 0.0019 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0075 | 0.0825 | 0.0791 |
Brugia malayi | hypothetical protein | 0.009 | 0.1011 | 0.1011 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0012 | 0.0019 | 0.0019 |
Brugia malayi | Animal haem peroxidase family protein | 0.009 | 0.1011 | 0.1011 |
Echinococcus granulosus | dihydropyrimidine dehydrogenase NADP | 0.0074 | 0.0804 | 0.0804 |
Trichomonas vaginalis | mercuric reductase, putative | 0.0278 | 0.3382 | 1 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0278 | 0.3382 | 0.3357 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0074 | 0.0804 | 0.1378 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0012 | 0.0019 | 0.0019 |
Echinococcus granulosus | transcription factor Dp 1 | 0.0044 | 0.0424 | 0.0424 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.1011 | 0.1011 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0012 | 0.0019 | 0.0019 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0012 | 0.0019 | 0.0019 |
Entamoeba histolytica | disulphide oxidoreductase, putative | 0.0074 | 0.0804 | 0.1849 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0019 | 0.0019 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0012 | 0.0019 | 0.0019 |
Onchocerca volvulus | Chorion peroxidase homolog | 0.009 | 0.1011 | 0.238 |
Mycobacterium tuberculosis | Probable reductase | 0.0074 | 0.0804 | 0.0429 |
Plasmodium vivax | type II NADH:ubiquinone oxidoreductase, putative | 0.0074 | 0.0804 | 0.0729 |
Onchocerca volvulus | Protein cereblon homolog | 0.0342 | 0.4186 | 1 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0278 | 0.3382 | 1 |
Toxoplasma gondii | pyridine nucleotide-disulfide oxidoreductase domain-containing protein | 0.0074 | 0.0804 | 0.0804 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0019 | 0.0019 |
Toxoplasma gondii | pyridine nucleotide-disulfide oxidoreductase domain-containing protein | 0.0074 | 0.0804 | 0.0804 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0041 | 0.0392 | 0.0356 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0392 | 0.0392 |
Mycobacterium ulcerans | NADH dehydrogenase | 0.0074 | 0.0804 | 0.1378 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0012 | 0.0019 | 0.0019 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0392 | 0.0392 |
Echinococcus granulosus | tyrosyl DNA phosphodiesterase 1 | 0.0075 | 0.0825 | 0.0825 |
Entamoeba histolytica | glutamate synthase beta subunit, putative | 0.0074 | 0.0804 | 0.1849 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0278 | 0.3382 | 0.3112 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0041 | 0.0392 | 0.0392 |
Trypanosoma cruzi | 2,4-dienoyl-coa reductase fadh1, putative | 0.0074 | 0.0804 | 0.077 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0019 | 0.0019 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0012 | 0.0019 | 0.0019 |
Toxoplasma gondii | selenide, water dikinase | 0.0074 | 0.0804 | 0.0804 |
Mycobacterium ulcerans | hypothetical protein | 0.0074 | 0.0804 | 0.1378 |
Leishmania major | trypanothione reductase | 0.0802 | 1 | 1 |
Giardia lamblia | NADH oxidase lateral transfer candidate | 0.0278 | 0.3382 | 1 |
Plasmodium vivax | ferrodoxin reductase, putative | 0.0074 | 0.0804 | 0.0729 |
Schistosoma mansoni | hypothetical protein | 0.0387 | 0.4761 | 0.4761 |
Trypanosoma brucei | trypanothione reductase | 0.0802 | 1 | 1 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0278 | 0.3382 | 0.3357 |
Schistosoma mansoni | sulfide quinone reductase | 0.0074 | 0.0804 | 0.0804 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0012 | 0.0019 | 0.0019 |
Mycobacterium ulcerans | NADPH:adrenodoxin oxidoreductase FprA | 0.0074 | 0.0804 | 0.1378 |
Leishmania major | acetoin dehydrogenase e3 component-like protein | 0.0278 | 0.3382 | 0.3357 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.1011 | 0.1011 |
Loa Loa (eye worm) | hypothetical protein | 0.0074 | 0.0804 | 0.0804 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0392 | 0.0392 |
Echinococcus granulosus | geminin | 0.0387 | 0.4761 | 0.4761 |
Brugia malayi | beta-lactamase family protein | 0.0041 | 0.0392 | 0.0392 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0278 | 0.3382 | 0.3382 |
Trichomonas vaginalis | glutathione reductase, putative | 0.0278 | 0.3382 | 1 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0802 | 1 | 1 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0041 | 0.0392 | 0.1061 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0041 | 0.0392 | 0.0392 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0074 | 0.0804 | 0.0429 |
Trypanosoma brucei | 2,4-dienoyl-coa reductase-like protein | 0.0074 | 0.0804 | 0.077 |
Mycobacterium tuberculosis | Possible dehydrogenase/reductase | 0.0074 | 0.0804 | 0.0429 |
Plasmodium falciparum | thioredoxin reductase | 0.0278 | 0.3382 | 0.3382 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, mitochondrial | 0.0278 | 0.3382 | 0.3382 |
Schistosoma mansoni | thyroid hormone receptor | 0.0155 | 0.1835 | 0.1835 |
Onchocerca volvulus | Peroxidasin homolog | 0.009 | 0.1011 | 0.238 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0041 | 0.0392 | 0.1061 |
Trypanosoma cruzi | 2,4-dienoyl-coa reductase-like protein, putative | 0.0074 | 0.0804 | 0.077 |
Entamoeba histolytica | NAD(FAD)-dependent dehydrogenase, putative | 0.0074 | 0.0804 | 0.1849 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0118 | 0.0118 |
Echinococcus multilocularis | dihydropyrimidine dehydrogenase (NADP+) | 0.0074 | 0.0804 | 0.0804 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0012 | 0.0019 | 0.0019 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0012 | 0.0019 | 0.0019 |
Trypanosoma cruzi | pyridine nucleotide-disulphide oxidoreductase, putative | 0.0074 | 0.0804 | 0.077 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0012 | 0.0019 | 0.0019 |
Mycobacterium ulcerans | glutamate synthase subunit beta | 0.0074 | 0.0804 | 0.1378 |
Echinococcus multilocularis | apoptosis inducing factor 1 mitochondrial | 0.0074 | 0.0804 | 0.0804 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0019 | 0.0019 |
Brugia malayi | Thioredoxin reductase | 0.0802 | 1 | 1 |
Onchocerca volvulus | 0.009 | 0.1011 | 0.238 | |
Loa Loa (eye worm) | animal heme peroxidase | 0.009 | 0.1011 | 0.1011 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0041 | 0.0392 | 0.1061 |
Echinococcus multilocularis | transcription factor Dp 1 | 0.0044 | 0.0424 | 0.0424 |
Schistosoma mansoni | peroxidasin | 0.009 | 0.1011 | 0.1011 |
Trypanosoma cruzi | NADH dehydrogenase, putative | 0.0074 | 0.0804 | 0.077 |
Loa Loa (eye worm) | animal heme peroxidase | 0.009 | 0.1011 | 0.1011 |
Brugia malayi | nuclear receptor NHR-88 | 0.0012 | 0.0019 | 0.0019 |
Echinococcus granulosus | apoptosis inducing factor 1 mitochondrial | 0.0074 | 0.0804 | 0.0804 |
Loa Loa (eye worm) | animal heme peroxidase | 0.009 | 0.1011 | 0.1011 |
Trypanosoma cruzi | pyridine nucleotide-disulphide oxidoreductase, putative | 0.0074 | 0.0804 | 0.077 |
Brugia malayi | Peroxidasin | 0.009 | 0.1011 | 0.1011 |
Trichomonas vaginalis | apoptosis inducing factor, putative | 0.0074 | 0.0804 | 0.2293 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0278 | 0.3382 | 0.3112 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0278 | 0.3382 | 0.3382 |
Schistosoma mansoni | thyroid hormone receptor | 0.0155 | 0.1835 | 0.1835 |
Brugia malayi | Bloom's syndrome protein homolog | 0.0024 | 0.0181 | 0.0181 |
Schistosoma mansoni | tyrosyl-DNA phosphodiesterase | 0.0075 | 0.0825 | 0.0825 |
Loa Loa (eye worm) | animal heme peroxidase | 0.009 | 0.1011 | 0.1011 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase family protein | 0.0074 | 0.0804 | 0.0804 |
Leishmania major | NADH dehydrogenase, putative | 0.0074 | 0.0804 | 0.077 |
Trypanosoma brucei | dihydrolipoyl dehydrogenase | 0.0278 | 0.3382 | 0.3357 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0802 | 1 | 1 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0144 | 0.1689 | 0.1689 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0012 | 0.0019 | 0.0019 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0012 | 0.0019 | 0.0019 |
Echinococcus multilocularis | geminin | 0.0387 | 0.4761 | 0.4761 |
Schistosoma mansoni | glutamate synthase | 0.0074 | 0.0804 | 0.0804 |
Toxoplasma gondii | NADH dehydrogenase (NDH2-II) | 0.0074 | 0.0804 | 0.0804 |
Entamoeba histolytica | dihydropyrimidine dehydrogenase, putative | 0.0074 | 0.0804 | 0.1849 |
Leishmania major | hypothetical protein, conserved | 0.0074 | 0.0804 | 0.077 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0278 | 0.3382 | 0.3382 |
Toxoplasma gondii | NADPH-glutathione reductase | 0.0278 | 0.3382 | 0.3382 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0012 | 0.0019 | 0.0019 |
Plasmodium falciparum | ferrodoxin reductase-like protein | 0.0074 | 0.0804 | 0.0804 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0012 | 0.0019 | 0.0019 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0074 | 0.0804 | 0.0429 |
Brugia malayi | beta-lactamase family protein | 0.0041 | 0.0392 | 0.0392 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0041 | 0.0392 | 0.1061 |
Mycobacterium ulcerans | NADPH:adrenodoxin oxidoreductase FprB | 0.0074 | 0.0804 | 0.1378 |
Echinococcus multilocularis | protein cereblon | 0.0342 | 0.4186 | 0.4186 |
Mycobacterium tuberculosis | NADPH:adrenodoxin oxidoreductase FprA (NADPH-ferredoxin reductase) | 0.0074 | 0.0804 | 0.0429 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0012 | 0.0019 | 0.0019 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0012 | 0.0019 | 0.0019 |
Echinococcus granulosus | FTZ F1 alpha | 0.0012 | 0.0019 | 0.0019 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0012 | 0.0019 | 0.0019 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0012 | 0.0019 | 0.0019 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, apicoplast | 0.0278 | 0.3382 | 0.3382 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0278 | 0.3382 | 0.3357 |
Echinococcus granulosus | dihydropyrimidine dehydrogenase NADP | 0.0074 | 0.0804 | 0.0804 |
Plasmodium falciparum | glutathione reductase | 0.0802 | 1 | 1 |
Leishmania major | 2,4-dienoyl-coa reductase fadh1, putative | 0.0074 | 0.0804 | 0.077 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.1011 | 0.1011 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.0016 | 0.0079 | 0.0079 |
Brugia malayi | Animal haem peroxidase family protein | 0.009 | 0.1011 | 0.1011 |
Echinococcus granulosus | protein cereblon | 0.0342 | 0.4186 | 0.4186 |
Trichomonas vaginalis | dihydroorotate dehydrogenase, putative | 0.0074 | 0.0804 | 0.2293 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0278 | 0.3382 | 0.3357 |
Onchocerca volvulus | Peroxidase homolog | 0.009 | 0.1011 | 0.238 |
Brugia malayi | beta-lactamase | 0.0041 | 0.0392 | 0.0392 |
Echinococcus multilocularis | pyridine nucleotide disulfide oxidoreductase | 0.0074 | 0.0804 | 0.0804 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0278 | 0.3382 | 1 |
Trichomonas vaginalis | disulfide oxidoreductase, putative | 0.0074 | 0.0804 | 0.2293 |
Loa Loa (eye worm) | beta-lactamase | 0.0041 | 0.0392 | 0.0392 |
Mycobacterium tuberculosis | Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate | 0.0074 | 0.0804 | 0.0429 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0012 | 0.0019 | 0.0019 |
Brugia malayi | follicle stimulating hormone receptor | 0.0265 | 0.3214 | 0.3214 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase, point mutation | 0.0278 | 0.3382 | 0.3357 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0012 | 0.0019 | 0.0019 |
Trichomonas vaginalis | disulfide oxidoreductase, putative | 0.0074 | 0.0804 | 0.2293 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0012 | 0.0019 | 0.0019 |
Trichomonas vaginalis | disulfide oxidoreductase, putative | 0.0074 | 0.0804 | 0.2293 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0392 | 0.0392 |
Brugia malayi | Blistered cuticle protein 3 | 0.009 | 0.1011 | 0.1011 |
Brugia malayi | nuclear hormone receptor | 0.0012 | 0.0019 | 0.0019 |
Echinococcus multilocularis | bloom syndrome protein | 0.0024 | 0.0181 | 0.0181 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0074 | 0.0804 | 0.077 |
Schistosoma mansoni | hypothetical protein | 0.0074 | 0.0804 | 0.0804 |
Toxoplasma gondii | non-proton pumping type-II NADH dehydrogenase I | 0.0074 | 0.0804 | 0.0804 |
Brugia malayi | hypothetical protein | 0.0342 | 0.4186 | 0.4186 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0012 | 0.0019 | 0.0019 |
Echinococcus multilocularis | tyrosyl DNA phosphodiesterase 1 | 0.0075 | 0.0825 | 0.0825 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase | 0.0278 | 0.3382 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.1011 | 0.1011 |
Echinococcus granulosus | peroxidasin | 0.009 | 0.1011 | 0.1011 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0074 | 0.0804 | 0.077 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0012 | 0.0019 | 0.0019 |
Loa Loa (eye worm) | hypothetical protein | 0.0362 | 0.4449 | 0.4449 |
Onchocerca volvulus | Peroxidasin homolog | 0.009 | 0.1011 | 0.238 |
Leishmania major | hypothetical protein, conserved | 0.0074 | 0.0804 | 0.077 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0802 | 1 | 1 |
Onchocerca volvulus | 0.0041 | 0.0392 | 0.0896 | |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0019 | 0.0019 |
Trypanosoma brucei | pyridine nucleotide-disulphide oxidoreductase, putative | 0.0074 | 0.0804 | 0.077 |
Schistosoma mansoni | sulfide quinone reductase | 0.0074 | 0.0804 | 0.0804 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0012 | 0.0019 | 0.0019 |
Echinococcus granulosus | NADPH:adrenodoxin oxidoreductase | 0.0074 | 0.0804 | 0.0804 |
Brugia malayi | Tyrosyl-DNA phosphodiesterase family protein | 0.0075 | 0.0825 | 0.0825 |
Plasmodium falciparum | ADP-dependent DNA helicase RecQ | 0.0021 | 0.0143 | 0.0143 |
Echinococcus multilocularis | glutamate synthase | 0.0074 | 0.0804 | 0.0804 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.1011 | 0.1011 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0012 | 0.0019 | 0.0019 |
Plasmodium vivax | NAD(P)H-dependent glutamate synthase, putative | 0.0074 | 0.0804 | 0.0729 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0278 | 0.3382 | 0.3382 |
Trypanosoma brucei | NADPH:adrenodoxin oxidoreductase, mitochondrial, putative | 0.0074 | 0.0804 | 0.077 |
Giardia lamblia | Glutamate synthase | 0.0074 | 0.0804 | 0.2378 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0802 | 1 | 1 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0263 | 0.3191 | 0.2913 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0074 | 0.0804 | 0.0429 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0012 | 0.0019 | 0.0019 |
Toxoplasma gondii | pyridine nucleotide-disulfide oxidoreductase domain-containing protein | 0.0074 | 0.0804 | 0.0804 |
Plasmodium falciparum | thioredoxin reductase | 0.0802 | 1 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0012 | 0.0019 | 0.0019 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0802 | 1 | 1 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0278 | 0.3382 | 0.3357 |
Trypanosoma cruzi | NADH dehydrogenase, putative | 0.0074 | 0.0804 | 0.077 |
Brugia malayi | alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase | 0.0204 | 0.2451 | 0.2451 |
Mycobacterium ulcerans | NADH dehydrogenase Ndh1 | 0.0074 | 0.0804 | 0.1378 |
Mycobacterium ulcerans | NADH dehydrogenase Ndh | 0.0074 | 0.0804 | 0.1378 |
Loa Loa (eye worm) | hypothetical protein | 0.0342 | 0.4186 | 0.4186 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0074 | 0.0804 | 0.0429 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0041 | 0.0392 | 0.0356 |
Mycobacterium ulcerans | monoxygenase | 0.0074 | 0.0804 | 0.1378 |
Echinococcus multilocularis | NADPH:adrenodoxin oxidoreductase | 0.0074 | 0.0804 | 0.0804 |
Echinococcus granulosus | bloom syndrome protein | 0.0024 | 0.0181 | 0.0181 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0012 | 0.0019 | 0.0019 |
Onchocerca volvulus | 0.009 | 0.1011 | 0.238 | |
Brugia malayi | Animal haem peroxidase family protein | 0.009 | 0.1011 | 0.1011 |
Schistosoma mansoni | peroxidasin | 0.009 | 0.1011 | 0.1011 |
Brugia malayi | Animal haem peroxidase family protein | 0.009 | 0.1011 | 0.1011 |
Leishmania major | tyrosyl-DNA phosphodiesterase 1 | 0.0075 | 0.0825 | 0.0791 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0012 | 0.0019 | 0.0019 |
Mycobacterium ulcerans | flavoprotein disulfide reductase | 0.0278 | 0.3382 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0019 | 0.0019 |
Brugia malayi | hypothetical protein | 0.0139 | 0.1629 | 0.1629 |
Schistosoma mansoni | hypothetical protein | 0.0144 | 0.1689 | 0.1689 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0041 | 0.0392 | 0.0392 |
Mycobacterium tuberculosis | Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot | 0.0278 | 0.3382 | 0.3112 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0041 | 0.0392 | 0.1061 |
Trypanosoma brucei | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0075 | 0.0825 | 0.0791 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0019 | 0.0019 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0041 | 0.0392 | 0.0392 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0144 | 0.1689 | 0.1689 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0012 | 0.0019 | 0.0019 |
Mycobacterium tuberculosis | Probable thioredoxin reductase TrxB2 (TRXR) (TR) | 0.0074 | 0.0804 | 0.0429 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.1011 | 0.1011 |
Leishmania major | 2,4-dienoyl-coa reductase-like protein | 0.0074 | 0.0804 | 0.077 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0075 | 0.0825 | 0.0791 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0278 | 0.3382 | 0.3357 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0278 | 0.3382 | 0.3357 |
Entamoeba histolytica | tyrosyl-DNA phosphodiesterase, putative | 0.0075 | 0.0825 | 0.1899 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0802 | 1 | 1 |
Trichomonas vaginalis | disulfide oxidoreductase, putative | 0.0074 | 0.0804 | 0.2293 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0012 | 0.0019 | 0.0019 |
Loa Loa (eye worm) | programmed cell death 8 | 0.0074 | 0.0804 | 0.0804 |
Trichomonas vaginalis | dihydropyrimidine dehydrogenase, putative | 0.0074 | 0.0804 | 0.2293 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0278 | 0.3382 | 0.3357 |
Onchocerca volvulus | Dual oxidase homolog | 0.009 | 0.1011 | 0.238 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0074 | 0.0804 | 0.0429 |
Mycobacterium ulcerans | thioredoxin reductase TrxB2 | 0.0074 | 0.0804 | 0.1378 |
Trichomonas vaginalis | disulfide oxidoreductase, putative | 0.0074 | 0.0804 | 0.2293 |
Loa Loa (eye worm) | RecQ helicase | 0.0024 | 0.0181 | 0.0181 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase family protein | 0.0074 | 0.0804 | 0.0804 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0012 | 0.0019 | 0.0019 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.1011 | 0.1011 |
Plasmodium falciparum | NAD(P)H-dependent glutamate synthase, putative | 0.0074 | 0.0804 | 0.0804 |
Plasmodium vivax | glutathione reductase, putative | 0.0802 | 1 | 1 |
Mycobacterium leprae | PROBABLE NADPH:ADRENODOXIN OXIDOREDUCTASE FPRB (ADRENODOXIN REDUCTASE) (AR) (FERREDOXIN-NADP(+) REDUCTASE) | 0.0074 | 0.0804 | 0.1378 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0278 | 0.3382 | 0.3357 |
Plasmodium falciparum | glutathione reductase | 0.0278 | 0.3382 | 0.3382 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0041 | 0.0392 | 0.0356 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.1011 | 0.1011 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.1011 | 0.1011 |
Onchocerca volvulus | 0.0041 | 0.0392 | 0.0896 | |
Leishmania major | hypothetical protein, conserved | 0.0041 | 0.0392 | 0.0356 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0012 | 0.0019 | 0.0019 |
Chlamydia trachomatis | dihydrolipoyl dehydrogenase | 0.0278 | 0.3382 | 1 |
Trichomonas vaginalis | DNA helicase recq1, putative | 0.0024 | 0.0181 | 0.0429 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0278 | 0.3382 | 0.3357 |
Loa Loa (eye worm) | tyrosyl-DNA phosphodiesterase | 0.0075 | 0.0825 | 0.0825 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0012 | 0.0019 | 0.0019 |
Trichomonas vaginalis | disulfide oxidoreductase, putative | 0.0074 | 0.0804 | 0.2293 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0278 | 0.3382 | 0.3357 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0012 | 0.0019 | 0.0019 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0392 | 0.0392 |
Echinococcus multilocularis | dihydropyrimidine dehydrogenase (NADP+) | 0.0074 | 0.0804 | 0.0804 |
Toxoplasma gondii | ABC1 family protein | 0.0041 | 0.0392 | 0.0392 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0155 | 0.1835 | 0.1835 |
Onchocerca volvulus | 0.0074 | 0.0804 | 0.1885 | |
Trichomonas vaginalis | dihydroorotate dehydrogenase, putative | 0.0074 | 0.0804 | 0.2293 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0041 | 0.0392 | 0.0392 |
Leishmania major | hypothetical protein, conserved | 0.0074 | 0.0804 | 0.077 |
Loa Loa (eye worm) | blistered cuticle protein 3 | 0.009 | 0.1011 | 0.1011 |
Onchocerca volvulus | 0.009 | 0.1011 | 0.238 | |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0012 | 0.0019 | 0.0019 |
Trichomonas vaginalis | glutamate synthase, putative | 0.0074 | 0.0804 | 0.2293 |
Echinococcus granulosus | sulfide:quinone oxidoreductase | 0.0074 | 0.0804 | 0.0804 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0278 | 0.3382 | 0.3357 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0012 | 0.0019 | 0.0019 |
Onchocerca volvulus | Peroxidase homolog | 0.009 | 0.1011 | 0.238 |
Entamoeba histolytica | pyridine nucleotide-disulfide oxidoreductase family protein | 0.0074 | 0.0804 | 0.1849 |
Trypanosoma brucei | pyridine nucleotide-disulphide oxidoreductase, putative | 0.0074 | 0.0804 | 0.077 |
Treponema pallidum | NADH oxidase | 0.0278 | 0.3382 | 1 |
Trichomonas vaginalis | DNA helicase recq, putative | 0.0024 | 0.0181 | 0.0429 |
Echinococcus multilocularis | sulfide:quinone oxidoreductase | 0.0074 | 0.0804 | 0.0804 |
Giardia lamblia | Thioredoxin reductase | 0.0074 | 0.0804 | 0.2378 |
Toxoplasma gondii | pyruvate dehydrogenase complex subunit PDH-E3II | 0.0278 | 0.3382 | 0.3382 |
Mycobacterium leprae | Probable NADPH:adrenodoxin oxidoreductase FprA (NADPH-FERREDOXIN REDUCTASE) | 0.0074 | 0.0804 | 0.1378 |
Brugia malayi | steroid hormone receptor | 0.0012 | 0.0019 | 0.0019 |
Toxoplasma gondii | thioredoxin reductase | 0.0802 | 1 | 1 |
Entamoeba histolytica | hypothetical protein, conserved | 0.0342 | 0.4186 | 1 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0278 | 0.3382 | 0.3112 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0392 | 0.0392 |
Trichomonas vaginalis | esterase, putative | 0.0041 | 0.0392 | 0.1061 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.1011 | 0.1011 |
Mycobacterium ulcerans | ferredoxin reductase | 0.0074 | 0.0804 | 0.1378 |
Mycobacterium leprae | Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate | 0.0074 | 0.0804 | 0.1378 |
Echinococcus granulosus | pyridine nucleotide disulfide oxidoreductase | 0.0074 | 0.0804 | 0.0804 |
Schistosoma mansoni | hypothetical protein | 0.0387 | 0.4761 | 0.4761 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.1011 | 0.1011 |
Trichomonas vaginalis | dihydrolipoamide dehydrogenase, putative | 0.0074 | 0.0804 | 0.2293 |
Trypanosoma brucei | NADH dehydrogenase | 0.0074 | 0.0804 | 0.077 |
Entamoeba histolytica | thioredoxin reductase, putative | 0.0074 | 0.0804 | 0.1849 |
Mycobacterium leprae | THIOREDOXIN TRXC (TRX) (MPT46) | 0.0074 | 0.0804 | 0.1378 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.1011 | 0.1011 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, mitochondrial, putative | 0.0278 | 0.3382 | 0.3328 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0012 | 0.0019 | 0.0019 |
Onchocerca volvulus | 0.0041 | 0.0392 | 0.0896 | |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.001 | 0.000000000057866 | 0.000000000057866 |
Trypanosoma cruzi | NADPH:adrenodoxin oxidoreductase, mitochondrial, putative | 0.0074 | 0.0804 | 0.077 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, apicoplast, putative | 0.0278 | 0.3382 | 0.3328 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0012 | 0.0019 | 0.0019 |
Schistosoma mansoni | hypothetical protein | 0.0342 | 0.4186 | 0.4186 |
Plasmodium vivax | hypothetical protein, conserved | 0.0041 | 0.0392 | 0.0314 |
Mycobacterium ulcerans | dehydrogenase | 0.0074 | 0.0804 | 0.1378 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0019 | 0.0019 |
Loa Loa (eye worm) | glutathione reductase | 0.0802 | 1 | 1 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein | 0.0204 | 0.2451 | 0.2451 |
Loa Loa (eye worm) | pyridine nucleotide-disufhide oxidoreductase | 0.0074 | 0.0804 | 0.0804 |
Brugia malayi | glutamate synthase | 0.0074 | 0.0804 | 0.0804 |
Leishmania major | 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein | 0.0278 | 0.3382 | 0.3357 |
Mycobacterium ulcerans | NADPH dependent 2,4-dienoyl-CoA reductase FadH | 0.0074 | 0.0804 | 0.1378 |
Schistosoma mansoni | glutamate synthase | 0.0074 | 0.0804 | 0.0804 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0012 | 0.0019 | 0.0019 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.1011 | 0.1011 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.