Detailed information for compound 262135

Basic information

Technical information
  • TDR Targets ID: 262135
  • Name: N-(4-chloro-1-oxo-3-propoxyisochromen-7-yl)-3 -phenylpropanamide
  • MW: 385.841 | Formula: C21H20ClNO4
  • H donors: 1 H acceptors: 2 LogP: 4.4 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCOc1oc(=O)c2c(c1Cl)ccc(c2)NC(=O)CCc1ccccc1
  • InChi: 1S/C21H20ClNO4/c1-2-12-26-21-19(22)16-10-9-15(13-17(16)20(25)27-21)23-18(24)11-8-14-6-4-3-5-7-14/h3-7,9-10,13H,2,8,11-12H2,1H3,(H,23,24)
  • InChiKey: SWNXQSSLFHEFKT-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-(4-chloro-1-oxo-3-propoxy-isochromen-7-yl)-3-phenyl-propanamide
  • N-(4-chloro-1-oxo-3-propoxy-2-benzopyran-7-yl)-3-phenylpropanamide
  • N-(4-chloro-1-keto-3-propoxy-isochromen-7-yl)-3-phenyl-propionamide
  • N-(4-chloro-1-oxo-3-propoxy-7-isochromenyl)-3-phenylpropanamide

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.003 0.0518 0.1673
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.003 0.0518 0.0518
Trypanosoma brucei aldo-keto reductase, putative 0.003 0.0518 1
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0027 0.0474 1
Echinococcus multilocularis neuropeptides capa receptor 0.0005 0.0024 0.0024
Echinococcus multilocularis rhodopsin orphan GPCR 0.0005 0.0024 0.0024
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0007 0.0077 0.009
Schistosoma mansoni opsin-like receptor 0.0005 0.0024 0.0028
Echinococcus granulosus neuropeptides capa receptor 0.0005 0.0024 0.0028
Loa Loa (eye worm) hypothetical protein 0.003 0.0518 0.1673
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0006 0.0042 0.0133
Echinococcus multilocularis G-protein coupled receptor, putative 0.0005 0.0024 0.0024
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0039 0.0708 0.083
Schistosoma mansoni hypothetical protein 0.0005 0.0024 0.0028
Trypanosoma brucei inositol-1,4,5-trisphosphate (IP3) 5-phosphatase, putative 0.0006 0.0042 0.0659
Trypanosoma brucei RNA editing exonuclease 2 0.0006 0.0042 0.0659
Brugia malayi hypothetical protein 0.0004 0.0009 0.0026
Brugia malayi hypothetical protein 0.0005 0.0024 0.0077
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0005 0.0024 0.0028
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0005 0.0024 0.0028
Trypanosoma cruzi inositol 5-phosphatase 1, putative 0.0006 0.0042 0.0659
Trichomonas vaginalis aldo-keto reductase, putative 0.003 0.0518 0.1448
Echinococcus granulosus orexin receptor type 2 0.0005 0.0024 0.0028
Loa Loa (eye worm) GTP-binding regulatory protein alpha chain 0.0004 0.0011 0.0035
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0005 0.0024 0.0024
Echinococcus multilocularis exonuclease 1 0.0004 0.0008 0.0008
Echinococcus granulosus rhodopsin orphan GPCR 0.0005 0.0024 0.0028
Schistosoma mansoni neuropeptide receptor 0.0005 0.0024 0.0028
Schistosoma mansoni amine GPCR 0.0005 0.0024 0.0028
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0005 0.0024 0.0028
Schistosoma mansoni ferritin 0.0005 0.0038 0.0044
Trichomonas vaginalis aldo-keto reductase, putative 0.0009 0.0102 0.0267
Loa Loa (eye worm) hypothetical protein 0.0006 0.0042 0.0133
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0005 0.0024 0.0028
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0007 0.0077 0.009
Loa Loa (eye worm) hypothetical protein 0.0005 0.0024 0.0077
Trypanosoma brucei DNA-(apurinic or apyrimidinic site) lyase, putative 0.0006 0.0042 0.0659
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0006 0.0042 0.0659
Schistosoma mansoni opsin-like receptor 0.0005 0.0024 0.0028
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0006 0.0042 0.0133
Loa Loa (eye worm) melatonin receptor type 1A 0.0005 0.0024 0.0077
Leishmania major hypothetical protein, conserved 0.0006 0.0042 0.0398
Trichomonas vaginalis G protein (olf) alpha subunit, gnal, putative 0.0004 0.0011 0.0009
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-6 subunit 0.0004 0.0011 0.0035
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0006 0.0042 0.0659
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0007 0.0077 0.0247
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0006 0.0042 0.0133
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0093 0.1774 0.2078
Loa Loa (eye worm) oxidoreductase 0.003 0.0518 0.1673
Echinococcus multilocularis ferritin 0.0005 0.0038 0.0037
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0007 0.0077 0.009
Trichomonas vaginalis conserved hypothetical protein 0.0004 0.0013 0.0015
Loa Loa (eye worm) hypothetical protein 0.0004 0.0011 0.0035
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0093 0.1774 0.2079
Echinococcus multilocularis neuropeptide Y receptor 0.0005 0.0024 0.0024
Echinococcus multilocularis G protein coupled receptor 139 0.0005 0.0024 0.0024
Mycobacterium ulcerans oxidoreductase 0.003 0.0518 0.5895
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0007 0.0077 0.0247
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0027 0.0474 0.5355
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.003 0.0518 0.0518
Echinococcus granulosus neuropeptide receptor 0.0005 0.0024 0.0028
Loa Loa (eye worm) hypothetical protein 0.0004 0.0009 0.0026
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0006 0.0042 0.0133
Schistosoma mansoni apoferritin-2 0.0005 0.0038 0.0044
Trichomonas vaginalis type II inositol 5-phosphatase, putative 0.0006 0.0042 0.0095
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0006 0.0042 0.0659
Entamoeba histolytica sphingomyelinase C precursor, putative 0.0006 0.0042 0.0659
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0007 0.0077 0.0247
Echinococcus granulosus CCR4 NOT transcription complex subunit 6 0.0006 0.0042 0.0048
Onchocerca volvulus 0.0005 0.0024 0.0067
Echinococcus multilocularis rhodopsin orphan GPCR 0.0005 0.0024 0.0024
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.003 0.0518 0.1673
Schistosoma mansoni biogenic amine receptor 0.0005 0.0024 0.0028
Schistosoma mansoni microtubule-associated protein tau 0.0434 0.8534 1
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0006 0.0042 0.0659
Brugia malayi Dopamine receptor protein 2 0.0005 0.0024 0.0077
Entamoeba histolytica aldose reductase, putative 0.003 0.0518 1
Trichomonas vaginalis conserved hypothetical protein 0.0004 0.0013 0.0015
Echinococcus granulosus neuropeptide Y receptor 0.0005 0.0024 0.0028
Brugia malayi G protein-coupled receptor 0.0005 0.0024 0.0077
Onchocerca volvulus 0.0005 0.0024 0.0067
Brugia malayi guanine nucleotide-binding protein G-o protein alpha subunit 0.0004 0.0011 0.0035
Loa Loa (eye worm) hypothetical protein 0.0005 0.0024 0.0077
Trypanosoma cruzi pantothenate kinase subunit, putative 0.0006 0.0042 0.0659
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0005 0.0024 0.0067
Loa Loa (eye worm) hypothetical protein 0.0007 0.0077 0.0247
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0093 0.1774 0.5727
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0007 0.0077 0.0217
Toxoplasma gondii oxidoreductase, aldo/keto reductase family protein 0.0009 0.0102 0.1112
Leishmania major endonuclease/exonuclease protein-like protein 0.0006 0.0042 0.0398
Echinococcus multilocularis aldo keto reductase 0.003 0.0518 0.0518
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0093 0.1774 0.1774
Onchocerca volvulus 0.0182 0.3534 1
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.003 0.0518 0.0518
Brugia malayi Tachykinin-like peptides receptor 99D 0.0005 0.0024 0.0077
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0005 0.0024 0.0077
Giardia lamblia Flap structure-specific endonuclease 0.0019 0.0305 0.5824
Echinococcus granulosus g protein coupled receptor 0.0005 0.0024 0.0028
Trichomonas vaginalis aldo-keto reductase, putative 0.003 0.0518 0.1448
Plasmodium vivax exodeoxyribonuclease III, putative 0.0006 0.0042 0.0721
Echinococcus multilocularis allatostatin A receptor 0.0005 0.0024 0.0024
Plasmodium falciparum aldo-keto reductase, putative 0.0009 0.0102 0.2015
Entamoeba histolytica aldose reductase, putative 0.003 0.0518 1
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0007 0.0077 0.0077
Schistosoma mansoni thyroid hormone receptor 0.0007 0.0077 0.009
Plasmodium vivax endonuclease/exonuclease/phosphatase domain containing protein 0.0006 0.0042 0.0721
Echinococcus multilocularis gtp binding protein (I) alpha 1subunit 0.0004 0.0011 0.0011
Echinococcus granulosus rhodopsin orphan GPCR 0.0005 0.0024 0.0028
Schistosoma mansoni ap endonuclease 0.0027 0.0474 0.0556
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0006 0.0042 0.0659
Leishmania major RNA-editing complex protein MP100, putative 0.0006 0.0042 0.0398
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0027 0.0474 0.9137
Echinococcus granulosus aldo keto reductase 0.003 0.0518 0.0607
Onchocerca volvulus 0.003 0.0518 0.1466
Loa Loa (eye worm) neuropeptide F receptor 0.0005 0.0024 0.0077
Trypanosoma cruzi RNA-editing complex protein MP100, putative 0.0006 0.0042 0.0659
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0007 0.0077 0.009
Trichomonas vaginalis flap endonuclease-1, putative 0.0019 0.0305 0.0843
Loa Loa (eye worm) hypothetical protein 0.0005 0.0024 0.0077
Schistosoma mansoni potassium channel beta 0.0009 0.0102 0.0119
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.003 0.0518 0.0518
Echinococcus granulosus aldo keto reductase family 1 member B4 0.003 0.0518 0.0607
Giardia lamblia Aldose reductase 0.003 0.0518 1
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0007 0.0077 0.009
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0004 0.0013 0.0015
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0007 0.0077 0.0247
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0004 0.0011 0.0009
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.0004 0.0011 0.0035
Echinococcus granulosus aldo keto reductase family 1 member B4 0.003 0.0518 0.0607
Mycobacterium leprae Conserved hypothetical protein 0.0021 0.0349 0.6467
Echinococcus multilocularis traf and tnf receptor associated protein 0.0006 0.0042 0.0041
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0007 0.0077 0.009
Echinococcus granulosus g protein coupled receptor 0.0005 0.0024 0.0028
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0027 0.0474 0.0474
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0004 0.0013 0.0015
Loa Loa (eye worm) hypothetical protein 0.0005 0.0024 0.0077
Trichomonas vaginalis alcohol dehydrogenase, putative 0.0009 0.0102 0.0267
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0005 0.0024 0.0077
Loa Loa (eye worm) hypothetical protein 0.0007 0.0077 0.0247
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-12 subunit 0.0004 0.0011 0.0035
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0007 0.0077 0.0247
Echinococcus granulosus neuropeptide s receptor 0.0005 0.0024 0.0028
Echinococcus multilocularis DNA repair protein complementing XP G cells 0.0004 0.0008 0.0008
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0007 0.0077 0.0247
Trichomonas vaginalis conserved hypothetical protein 0.0004 0.0013 0.0015
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0007 0.0077 0.009
Trichomonas vaginalis set domain proteins, putative 0.0182 0.3534 1
Loa Loa (eye worm) hypothetical protein 0.0005 0.0024 0.0077
Trichomonas vaginalis sphingomyelinase C 2 precursor, putative 0.0006 0.0042 0.0095
Loa Loa (eye worm) hypothetical protein 0.0005 0.0024 0.0077
Loa Loa (eye worm) hypothetical protein 0.0005 0.0024 0.0077
Toxoplasma gondii aldehyde dehydrogenase 0.0046 0.0853 1
Loa Loa (eye worm) hypothetical protein 0.0005 0.0024 0.0077
Brugia malayi Serotonin receptor 0.0005 0.0024 0.0077
Mycobacterium tuberculosis Conserved protein 0.0009 0.0102 0.0787
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0005 0.0024 0.0024
Trichomonas vaginalis aldo-keto reductase, putative 0.003 0.0518 0.1448
Trichomonas vaginalis conserved hypothetical protein 0.0004 0.0013 0.0015
Wolbachia endosymbiont of Brugia malayi extracellular metallopeptidase 0.0464 0.913 1
Echinococcus granulosus tm gpcr rhodopsin 0.0005 0.0024 0.0028
Echinococcus granulosus synaptojanin 1 0.0006 0.0042 0.0048
Loa Loa (eye worm) hypothetical protein 0.0004 0.0011 0.0035
Schistosoma mansoni myosin xvIII 0.0005 0.0024 0.0028
Echinococcus granulosus peptide allatostatin:somatostatin 0.0005 0.0024 0.0028
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0006 0.0042 0.0659
Toxoplasma gondii aldose reductase, putative 0.003 0.0518 0.604
Mycobacterium ulcerans aldehyde dehydrogenase 0.0046 0.0853 1
Echinococcus multilocularis fmrfamide receptor 0.0005 0.0024 0.0024
Schistosoma mansoni apoferritin-2 0.0005 0.0038 0.0044
Brugia malayi ecdysteroid receptor 0.0007 0.0077 0.0247
Echinococcus granulosus neutral sphingomyelinase 0.0006 0.0042 0.0048
Onchocerca volvulus 0.003 0.0518 0.1466
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0006 0.0042 0.0133
Loa Loa (eye worm) hypothetical protein 0.0007 0.0077 0.0247
Brugia malayi Nuclear hormone receptor-like 1 0.0004 0.0009 0.0026
Onchocerca volvulus Putative neutral sphingomyelinase 0.0006 0.0042 0.0117
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0023 0.0393 0.0392
Trypanosoma brucei inositol/phosphatidylinositol phosphatase, putative 0.0006 0.0042 0.0659
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0005 0.0024 0.0028
Echinococcus granulosus tachykinin peptides receptor 99D 0.0005 0.0024 0.0028
Echinococcus granulosus flap endonuclease 1 0.0019 0.0305 0.0357
Loa Loa (eye worm) hypothetical protein 0.0005 0.0024 0.0077
Trichomonas vaginalis aldo-keto reductase, putative 0.003 0.0518 0.1448
Plasmodium vivax SET domain protein, putative 0.0023 0.0393 0.8249
Trichomonas vaginalis aldo-keto reductase, putative 0.003 0.0518 0.1448
Echinococcus multilocularis flap endonuclease 1 0.0019 0.0305 0.0305
Echinococcus multilocularis somatostatin receptor 0.0005 0.0024 0.0024
Loa Loa (eye worm) CCR4-NOT transcription complex subunit 6 family protein 0.0006 0.0042 0.0133
Loa Loa (eye worm) hypothetical protein 0.0005 0.0024 0.0077
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0005 0.0024 0.0024
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0006 0.0042 0.0659
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0019 0.0305 0.3518
Schistosoma mansoni nocturnin 0.0006 0.0042 0.0049
Echinococcus multilocularis neuropeptide receptor A26 0.0005 0.0024 0.0024
Brugia malayi neuropeptide F receptor 0.0005 0.0024 0.0077
Echinococcus multilocularis rhodopsin orphan GPCR 0.0005 0.0024 0.0024
Brugia malayi hypothetical protein 0.0004 0.0009 0.0026
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0005 0.0024 0.0077
Loa Loa (eye worm) hypothetical protein 0.0007 0.0077 0.0247
Echinococcus multilocularis expressed protein 0.0005 0.0038 0.0037
Schistosoma mansoni opsin-like receptor 0.0005 0.0024 0.0028
Mycobacterium tuberculosis Probable exported protein 0.0006 0.0042 0.0047
Brugia malayi nuclear receptor NHR-88 0.0007 0.0077 0.0247
Schistosoma mansoni hypothetical protein 0.0257 0.5031 0.5895
Loa Loa (eye worm) hypothetical protein 0.0005 0.0024 0.0077
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.003 0.0518 0.1448
Loa Loa (eye worm) hypothetical protein 0.0004 0.0009 0.0026
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0005 0.0038 0.0037
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0005 0.0024 0.0024
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0005 0.0024 0.0024
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.0004 0.0011 0.0013
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0004 0.0011 0.0013
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0004 0.0011 0.0009
Echinococcus granulosus 7TM GPCR rhodopsin 0.0005 0.0024 0.0028
Echinococcus multilocularis g protein coupled receptor 0.0005 0.0024 0.0024
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0093 0.1774 0.2079
Trichomonas vaginalis ferritin, putative 0.0005 0.0038 0.0085
Loa Loa (eye worm) hypothetical protein 0.0023 0.0393 0.1267
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0102 0.0267
Echinococcus multilocularis inositol polyphosphate 5 phosphatase OCRL 1 0.0006 0.0042 0.0041
Schistosoma mansoni cpg binding protein 0.0019 0.031 0.0364
Echinococcus granulosus tm gpcr rhodopsin 0.0005 0.0024 0.0028
Echinococcus granulosus guanine nucleotide binding protein G protein 0.0004 0.0011 0.0013
Onchocerca volvulus 0.0009 0.0102 0.0287
Schistosoma mansoni alpha-1 adrenergic receptor 0.0005 0.0024 0.0028
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0007 0.0077 0.009
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0007 0.0077 0.0247
Schistosoma mansoni ferritin 0.0005 0.0038 0.0044
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.0004 0.0011 0.0013
Schistosoma mansoni xp-G/rad2 DNA repair endonuclease family 0.0004 0.0008 0.0009
Giardia lamblia hypothetical protein 0.0006 0.0042 0.0659
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0005 0.0024 0.0028
Trichomonas vaginalis ap endonuclease, putative 0.0027 0.0474 0.1323
Loa Loa (eye worm) hypothetical protein 0.0004 0.0009 0.0026
Trichomonas vaginalis type IV inositol 5-phosphatase, putative 0.0006 0.0042 0.0095
Echinococcus multilocularis aldo keto reductase 0.003 0.0518 0.0518
Brugia malayi hypothetical protein 0.0004 0.0011 0.0035
Leishmania major prostaglandin f2-alpha synthase/D-arabinose dehydrogenase 0.003 0.0518 0.604
Loa Loa (eye worm) hypothetical protein 0.0004 0.0008 0.0024
Brugia malayi CXXC zinc finger family protein 0.0018 0.029 0.0935
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0007 0.0077 0.0247
Schistosoma mansoni amine GPCR 0.0005 0.0024 0.0028
Schistosoma mansoni hypothetical protein 0.0005 0.0024 0.0028
Schistosoma mansoni pol-related 0.003 0.0518 0.0608
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0007 0.0077 0.0247
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0093 0.1774 0.5727
Entamoeba histolytica endonuclease/exonuclease/phosphatase domain containing protein 0.0006 0.0042 0.0659
Echinococcus granulosus aldo keto reductase family 1 member B4 0.003 0.0518 0.0607
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0004 0.0009 0.0008
Echinococcus multilocularis deoxyribonuclease 1 2 0.0006 0.0042 0.0041
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0006 0.0042 0.0659
Echinococcus granulosus aldo keto reductase family 1 member B4 0.003 0.0518 0.0607
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0046 0.0853 0.0853
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.003 0.0518 0.0518
Loa Loa (eye worm) hypothetical protein 0.0004 0.0011 0.0035
Trypanosoma cruzi aldo/keto reductase, putative 0.003 0.0518 1
Onchocerca volvulus 0.003 0.0518 0.1466
Echinococcus granulosus expressed protein 0.0004 0.0011 0.0013
Loa Loa (eye worm) hypothetical protein 0.0006 0.0042 0.0133
Trypanosoma cruzi mitochondrial protein 99, putative 0.0006 0.0042 0.0659
Entamoeba histolytica alcohol dehydrogenase, putative 0.0009 0.0102 0.1841
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0027 0.0474 0.9137
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0006 0.0042 0.0133
Loa Loa (eye worm) XPG I-region family protein 0.0004 0.0008 0.0024
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0007 0.0077 0.0247
Treponema pallidum exodeoxyribonuclease (exoA) 0.0027 0.0474 1
Loa Loa (eye worm) hypothetical protein 0.0005 0.0024 0.0077
Schistosoma mansoni flap endonuclease-1 0.0017 0.0269 0.0316
Onchocerca volvulus 0.003 0.0518 0.1466
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0023 0.0393 0.0392
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0004 0.0013 0.0015
Onchocerca volvulus 0.0006 0.0042 0.0117
Echinococcus granulosus DNA repair protein complementing XP G cells 0.0004 0.0008 0.0009
Entamoeba histolytica aldose reductase, putative 0.003 0.0518 1
Echinococcus granulosus guanine nucleotide binding protein subunit 0.0004 0.0011 0.0013
Brugia malayi guanine nucleotide-binding protein alpha-3 subunit, putative 0.0004 0.0011 0.0035
Echinococcus granulosus neuropeptide Y receptor 0.0005 0.0024 0.0028
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0046 0.0853 1
Brugia malayi nuclear hormone receptor 0.0007 0.0077 0.0247
Loa Loa (eye worm) hypothetical protein 0.0005 0.0024 0.0077
Echinococcus granulosus somatostatin receptor 0.0005 0.0024 0.0028
Brugia malayi nuclear receptor RXR 0.0004 0.0009 0.0026
Echinococcus multilocularis neuropeptide Y receptor 0.0005 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0004 0.0009 0.0026
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0005 0.0024 0.0028
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0007 0.0077 0.0077
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0023 0.0393 0.4553
Brugia malayi G-protein alpha subunit 0.0004 0.0011 0.0035
Schistosoma mansoni adenoreceptor 0.0005 0.0024 0.0028
Entamoeba histolytica inositol polyphosphate 5-phosphatase, putative 0.0006 0.0042 0.0659
Trichomonas vaginalis aldo-keto reductase, putative 0.0009 0.0102 0.0267
Brugia malayi hypothetical protein 0.0005 0.0024 0.0077
Plasmodium falciparum endonuclease/exonuclease/phosphatase family protein, putative 0.0006 0.0042 0.0721
Echinococcus multilocularis cpg binding protein 0.0019 0.031 0.031
Echinococcus multilocularis FTZ F1 alpha 0.0007 0.0077 0.0077
Trypanosoma brucei prostaglandin f synthase 0.003 0.0518 1
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0005 0.0024 0.0024
Onchocerca volvulus 0.0005 0.0024 0.0067
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0004 0.0013 0.0015
Brugia malayi Melatonin receptor type 1A 0.0005 0.0024 0.0077
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0093 0.1774 0.2078
Echinococcus granulosus guanine nucleotide binding protein subunit 0.0004 0.0011 0.0013
Echinococcus granulosus expressed protein 0.0005 0.0038 0.0044
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0005 0.0024 0.0077
Schistosoma mansoni RAR-like nuclear receptor 0.0007 0.0077 0.009
Onchocerca volvulus 0.0005 0.0024 0.0067
Echinococcus granulosus exonuclease 1 0.0004 0.0008 0.0009
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0006 0.0042 0.0048
Echinococcus granulosus traf and tnf receptor associated protein 0.0006 0.0042 0.0048
Schistosoma mansoni histamine h1 receptor 0.0005 0.0024 0.0028
Schistosoma mansoni aldehyde dehydrogenase 0.0046 0.0853 0.1
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.0004 0.0011 0.0013
Trichomonas vaginalis aldo-keto reductase, putative 0.003 0.0518 0.1448
Onchocerca volvulus 0.0005 0.0024 0.0067
Echinococcus multilocularis neuropeptides capa receptor 0.0005 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0005 0.0024 0.0077
Echinococcus multilocularis aldehyde reductase 0.0021 0.0349 0.0348
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0005 0.0038 0.0044
Schistosoma mansoni ferritin 0.0005 0.0038 0.0044
Trypanosoma cruzi mitochondrial protein 99, putative 0.0006 0.0042 0.0659
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.003 0.0518 0.0518
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0006 0.0042 0.0659
Trichomonas vaginalis aldo-keto reductase, putative 0.003 0.0518 0.1448
Brugia malayi putative neuropeptide receptor 0.0005 0.0024 0.0077
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0006 0.0042 0.0659
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0046 0.0853 1
Schistosoma mansoni cpg binding protein 0.0018 0.029 0.034
Schistosoma mansoni neuropeptide receptor 0.0005 0.0024 0.0028
Brugia malayi Serotonin receptor 0.0005 0.0024 0.0077
Schistosoma mansoni aldehyde dehydrogenase 0.0046 0.0853 0.1
Treponema pallidum hypothetical protein 0.0006 0.0042 0.0088
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.003 0.0518 0.0518
Trichomonas vaginalis aldo-keto reductase, putative 0.003 0.0518 0.1448
Loa Loa (eye worm) G-protein coupled receptor 0.0005 0.0024 0.0077
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0006 0.0042 0.0659
Schistosoma mansoni neuropeptide f receptor 76f 0.0005 0.0024 0.0028
Schistosoma mansoni neutral sphingomyelinase 0.0006 0.0042 0.0049
Trichomonas vaginalis GTP-binding protein (q) alpha-11 subunit, gna11, putative 0.0004 0.0011 0.0009
Echinococcus granulosus hypothetical protein 0.0005 0.0024 0.0028
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0006 0.0059 0.0069
Onchocerca volvulus 0.0005 0.0024 0.0067
Echinococcus multilocularis neuropeptide receptor 0.0005 0.0024 0.0024
Schistosoma mansoni ap endonuclease 0.0027 0.0474 0.0556
Brugia malayi Guanine nucleotide-binding protein alpha-6 subunit, putative 0.0004 0.0011 0.0035
Echinococcus multilocularis g-protein coupled receptor 0.0005 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0005 0.0024 0.0077
Echinococcus granulosus microtubule associated protein 2 0.0434 0.8534 1
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0007 0.0077 0.0077
Echinococcus granulosus biogenic amine 5HT receptor 0.0005 0.0024 0.0028
Echinococcus granulosus dnaJ subfamily B 0.0257 0.5031 0.5895
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0005 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0005 0.0024 0.0077
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0005 0.0024 0.0024
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.0004 0.0011 0.0011
Loa Loa (eye worm) oxidoreductase 0.003 0.0518 0.1673
Loa Loa (eye worm) hypothetical protein 0.0005 0.0024 0.0077
Echinococcus granulosus rhodopsin orphan GPCR 0.0005 0.0024 0.0028
Schistosoma mansoni biogenic amine receptor 0.0005 0.0024 0.0028
Schistosoma mansoni amine GPCR 0.0005 0.0024 0.0028
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0004 0.0013 0.0015
Brugia malayi hypothetical protein 0.0005 0.0024 0.0077
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0006 0.0042 0.0398
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0006 0.0042 0.0133
Brugia malayi exodeoxyribonuclease III family protein 0.0027 0.0474 0.1531
Trichomonas vaginalis aldo/keto reductase, putative 0.003 0.0518 0.1448
Echinococcus granulosus gtp binding protein I alpha 1subunit 0.0004 0.0011 0.0013
Brugia malayi ORL1-like opioid receptor 0.0005 0.0024 0.0077
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0022 0.0368 0.0431
Schistosoma mansoni GTP-binding protein (I) alpha subunit gnai 0.0004 0.0011 0.0013
Onchocerca volvulus 0.0005 0.0024 0.0067
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0005 0.0024 0.0028
Trichomonas vaginalis aldo-keto reductase, putative 0.003 0.0518 0.1448
Brugia malayi hypothetical protein 0.0005 0.0024 0.0077
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0006 0.0042 0.0398
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.016 0.3097 1
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0006 0.0042 0.0659
Brugia malayi G-protein coupled receptor 0.0005 0.0024 0.0077
Onchocerca volvulus 0.0004 0.0011 0.0031
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.003 0.0518 0.0518
Schistosoma mansoni coup transcription factor 0.0007 0.0077 0.009
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0005 0.0024 0.0077
Loa Loa (eye worm) hypothetical protein 0.0005 0.0024 0.0077
Loa Loa (eye worm) hypothetical protein 0.0005 0.0024 0.0077
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0006 0.0042 0.0398
Brugia malayi hypothetical protein 0.0005 0.0024 0.0077
Echinococcus granulosus tm gpcr rhodopsin 0.0005 0.0024 0.0028
Brugia malayi G protein-coupled receptor F59B2.13 0.0005 0.0024 0.0077
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.003 0.0518 0.0518
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0005 0.0024 0.0028
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0005 0.0024 0.0024
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0005 0.0024 0.0028
Echinococcus multilocularis serotonin receptor 0.0005 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0005 0.0024 0.0077
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0006 0.0042 0.0095
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.0004 0.0011 0.0013
Onchocerca volvulus 0.0007 0.0077 0.0217
Leishmania major pantothenate kinase subunit, putative 0.0006 0.0042 0.0398
Leishmania major aldehyde reductase, putative,oxidoreductase, putative 0.003 0.0518 0.604
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0005 0.0024 0.0028
Loa Loa (eye worm) hypothetical protein 0.0005 0.0024 0.0077
Brugia malayi F/Y-rich N-terminus family protein 0.0006 0.0058 0.0186
Echinococcus granulosus aldo keto reductase family 1 member B4 0.003 0.0518 0.0607
Echinococcus granulosus aldo keto reductase 0.003 0.0518 0.0607
Brugia malayi Nuclear hormone receptor-like 1 0.0007 0.0077 0.0247
Schistosoma mansoni ocrl type II inositol 5-phosphatase 0.0006 0.0042 0.0049
Loa Loa (eye worm) steroid hormone receptor 0.0007 0.0077 0.0247
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0007 0.0077 0.0077
Echinococcus multilocularis microtubule associated protein 2 0.0434 0.8534 0.8534
Toxoplasma gondii histone lysine methyltransferase SET1 0.0035 0.0627 0.7323
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0005 0.0024 0.0028
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0006 0.0042 0.0133
Echinococcus multilocularis flap endonuclease GEN 1 0.0004 0.0008 0.0008
Trichomonas vaginalis aldo/keto reductase, putative 0.003 0.0518 0.1448
Loa Loa (eye worm) hypothetical protein 0.0004 0.0011 0.0035
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0005 0.0024 0.0028
Leishmania major prostaglandin f synthase, putative 0.003 0.0518 0.604
Echinococcus granulosus aldo keto reductase family 1 member B4 0.003 0.0518 0.0607
Schistosoma mansoni GTP-binding protein alpha subunit 0.0004 0.0011 0.0013
Loa Loa (eye worm) oxidoreductase 0.003 0.0518 0.1673
Brugia malayi glutamate-cysteine ligase modifier subunit 0.0009 0.0102 0.0328
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.0004 0.0011 0.0011
Leishmania major hypothetical protein, conserved 0.0006 0.0042 0.0398
Schistosoma mansoni neuropeptide F-like receptor 0.0005 0.0024 0.0028
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0023 0.0393 0.046
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0006 0.0042 0.0398
Echinococcus multilocularis rhodopsin orphan GPCR 0.0005 0.0024 0.0024
Echinococcus multilocularis expressed protein 0.0004 0.0011 0.0011
Schistosoma mansoni aldo-keto reductase 0.003 0.0518 0.0608
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0004 0.0011 0.0013
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0027 0.0474 0.048
Echinococcus multilocularis dro:myosuppressin receptor 0.0005 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0005 0.0024 0.0077
Trichomonas vaginalis aldo-keto reductase, putative 0.003 0.0518 0.1448
Loa Loa (eye worm) hypothetical protein 0.0004 0.0011 0.0035
Echinococcus granulosus cpg binding protein 0.0019 0.031 0.0363
Loa Loa (eye worm) hypothetical protein 0.0004 0.0008 0.0024
Echinococcus multilocularis sex peptide receptor 0.0005 0.0024 0.0024
Echinococcus granulosus allatostatin A receptor 0.0005 0.0024 0.0028
Brugia malayi GTP-binding regulatory protein alpha chain - starfish, putative 0.0004 0.0011 0.0035
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0006 0.0042 0.0133
Loa Loa (eye worm) G-protein coupled receptor 0.0005 0.0024 0.0077
Trichomonas vaginalis aldo-keto reductase, putative 0.003 0.0518 0.1448
Echinococcus multilocularis voltage gated potassium channel subunit 0.0009 0.0102 0.0102
Brugia malayi NADH-dependent xylose reductase 0.0009 0.0102 0.0328
Schistosoma mansoni exonuclease 0.0004 0.0008 0.0009
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.0004 0.0011 0.0011
Schistosoma mansoni amine GPCR 0.0005 0.0024 0.0028
Echinococcus granulosus neuropeptide receptor 0.0005 0.0024 0.0028
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0006 0.0042 0.0095
Loa Loa (eye worm) hypothetical protein 0.0005 0.0024 0.0077
Echinococcus multilocularis dnaJ subfamily B 0.0257 0.5031 0.5031
Leishmania major inositol/phosphatidylinositol phosphatase, putative 0.0006 0.0042 0.0398
Onchocerca volvulus 0.0005 0.0024 0.0067
Trichomonas vaginalis conserved hypothetical protein 0.0004 0.0013 0.0015
Echinococcus multilocularis aldo keto reductase 0.003 0.0518 0.0518
Echinococcus granulosus ecdysone induced protein 78C 0.0007 0.0077 0.009
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0005 0.0024 0.0028
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0005 0.0024 0.0028
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0005 0.0024 0.0028
Schistosoma mansoni hypothetical protein 0.0005 0.0024 0.0028
Echinococcus granulosus sex peptide receptor 0.0005 0.0024 0.0028
Schistosoma mansoni GTP-binding protein alpha subunit 0.0004 0.0011 0.0013
Loa Loa (eye worm) CXXC zinc finger family protein 0.0018 0.029 0.0935
Plasmodium vivax endonuclease/exonuclease/phosphatase domain containing protein 0.0006 0.0042 0.0721
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0004 0.0013 0.0015
Loa Loa (eye worm) hypothetical protein 0.0005 0.0024 0.0077
Echinococcus granulosus g protein coupled receptor 0.0005 0.0024 0.0028
Echinococcus granulosus voltage gated potassium channel subunit 0.0009 0.0102 0.0119
Mycobacterium tuberculosis Probable oxidoreductase 0.003 0.0518 0.5895
Trichomonas vaginalis aldo-keto reductase, putative 0.0009 0.0102 0.0267
Echinococcus multilocularis neuropeptide receptor 0.0005 0.0024 0.0024
Onchocerca volvulus 0.0005 0.0024 0.0067
Brugia malayi neuropeptide F receptor 0.0005 0.0024 0.0077
Trypanosoma cruzi endonuclease/exonuclease/phosphatase, putative 0.0006 0.0042 0.0659
Onchocerca volvulus 0.0006 0.0042 0.0117
Schistosoma mansoni xp-G/rad2 DNA repair endonuclease family member 0.0004 0.0008 0.0009
Echinococcus granulosus G protein coupled receptor 139 0.0005 0.0024 0.0028
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0006 0.0042 0.0133
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0005 0.0024 0.0028
Loa Loa (eye worm) glutamate-cysteine ligase modifier subunit 0.0009 0.0102 0.0328
Mycobacterium ulcerans hypothetical protein 0.0009 0.0102 0.0787
Loa Loa (eye worm) hypothetical protein 0.0005 0.0024 0.0077
Plasmodium falciparum carbon catabolite repressor protein 4, putative 0.0006 0.0042 0.0721
Trypanosoma brucei Inositol phosphosphingolipids phospholipase C 0.0006 0.0042 0.0659
Onchocerca volvulus 0.0005 0.0024 0.0067
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0093 0.1774 0.2079
Brugia malayi G-protein coupled receptor 0.0005 0.0024 0.0077
Echinococcus granulosus aldo keto reductase family 1, member B4 0.0009 0.0102 0.0119
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0005 0.0024 0.0028
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0005 0.0024 0.0077
Echinococcus multilocularis fmrfamide receptor 0.0005 0.0024 0.0024
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0005 0.0024 0.0024
Echinococcus multilocularis serotonin receptor 0.0005 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0007 0.0077 0.0247
Loa Loa (eye worm) hypothetical protein 0.0005 0.0024 0.0077
Schistosoma mansoni biogenic amine receptor 0.0005 0.0024 0.0028
Trichomonas vaginalis GTP-binding protein (z) alpha subunit, gnaz, putative 0.0004 0.0011 0.0009
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0004 0.0009 0.001
Brugia malayi guanine nucleotide-binding protein G(o), alpha subunit, putative 0.0004 0.0011 0.0035
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0007 0.0077 0.009
Brugia malayi Pre-SET motif family protein 0.0023 0.0393 0.1267
Giardia lamblia Aldose reductase 0.003 0.0518 1
Echinococcus multilocularis orexin receptor type 2 0.0005 0.0024 0.0024
Onchocerca volvulus Neuropeptide F receptor homolog 0.0005 0.0024 0.0067
Trypanosoma brucei aldo/keto reductase, putative 0.0009 0.0102 0.1841
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0005 0.0038 0.0037
Mycobacterium ulcerans aldehyde dehydrogenase 0.0046 0.0853 1
Onchocerca volvulus 0.0018 0.029 0.082
Schistosoma mansoni carbon catabolite repressor protein 0.0006 0.0042 0.0049
Entamoeba histolytica G protein alpha subunit, putative 0.0004 0.0011 0.0064
Trypanosoma cruzi aldo-keto reductase 0.003 0.0518 1
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0006 0.0042 0.0398
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0004 0.0009 0.001
Echinococcus granulosus neuropeptides capa receptor 0.0005 0.0024 0.0028
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0007 0.0077 0.0247
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0007 0.0077 0.0077
Loa Loa (eye worm) hypothetical protein 0.0007 0.0077 0.0247
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0005 0.0024 0.0024
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0006 0.0042 0.0041
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0005 0.0024 0.0077
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0005 0.0024 0.0028
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0006 0.0042 0.0398
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.003 0.0518 0.0518
Loa Loa (eye worm) hypothetical protein 0.0005 0.0024 0.0077
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0006 0.0042 0.0133
Toxoplasma gondii aldo/keto reductase family oxidoreductase 0.0009 0.0102 0.1112
Brugia malayi hypothetical protein 0.0005 0.0024 0.0077
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0007 0.0077 0.0247
Echinococcus granulosus rhodopsin orphan GPCR 0.0005 0.0024 0.0028
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0005 0.0024 0.0024
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0005 0.0024 0.0028
Onchocerca volvulus 0.003 0.0518 0.1466
Echinococcus granulosus fmrfamide receptor 0.0005 0.0024 0.0028
Loa Loa (eye worm) hypothetical protein 0.0006 0.0042 0.0133
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.0004 0.0011 0.0011
Loa Loa (eye worm) oxidoreductase 0.003 0.0518 0.1673
Loa Loa (eye worm) hypothetical protein 0.0005 0.0024 0.0077
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0027 0.0474 0.1531
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0006 0.0059 0.0059
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0027 0.0474 0.9137
Echinococcus granulosus serotonin receptor 0.0005 0.0024 0.0028
Echinococcus multilocularis g protein coupled receptor 0.0005 0.0024 0.0024
Plasmodium falciparum aldehyde reductase, putative 0.0009 0.0102 0.2015
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0027 0.0474 0.9137
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0005 0.0024 0.0028
Schistosoma mansoni retinoic acid receptor RXR 0.0007 0.0077 0.009
Plasmodium vivax flap endonuclease 1, putative 0.0019 0.0305 0.6374
Echinococcus granulosus aldo keto reductase family 1 member B4 0.003 0.0518 0.0607
Echinococcus granulosus mixed lineage leukemia protein mll 0.0005 0.0038 0.0044
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0005 0.0024 0.0028
Onchocerca volvulus Bile acid receptor homolog 0.0007 0.0077 0.0217
Loa Loa (eye worm) neuropeptide F receptor 0.0005 0.0024 0.0077
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0005 0.0024 0.0028
Brugia malayi Nuclear hormone receptor-like 1 0.0004 0.0009 0.0026
Brugia malayi Steroid receptor seven-up type 2 0.0007 0.0077 0.0247
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0027 0.0474 0.5355
Onchocerca volvulus 0.0005 0.0024 0.0067
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.003 0.0518 0.0518
Echinococcus granulosus guanine nucleotide binding protein G protein 0.0004 0.0011 0.0013
Mycobacterium leprae Possible oxidoreductase 0.0009 0.0102 0.1335
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0005 0.0024 0.0028
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0007 0.0077 0.0247
Echinococcus multilocularis rhodopsin orphan GPCR 0.0005 0.0024 0.0024
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.0004 0.0011 0.0013
Brugia malayi Dopamine receptor 0.0005 0.0024 0.0077
Onchocerca volvulus 0.0023 0.0393 0.1111
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0007 0.0077 0.009
Brugia malayi putative neuropeptide receptor NPR1 0.0005 0.0024 0.0077
Plasmodium falciparum carbon catabolite repressor protein 4, putative 0.0006 0.0042 0.0721
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0005 0.0024 0.0077
Loa Loa (eye worm) hypothetical protein 0.0006 0.0042 0.0133
Trichomonas vaginalis skeletal muscle/kidney enriched inositol 5-phosphatase, putative 0.0006 0.0042 0.0095
Plasmodium falciparum exodeoxyribonuclease III, putative 0.0006 0.0042 0.0721
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0004 0.0013 0.0015
Brugia malayi hypothetical protein 0.0005 0.0024 0.0077
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0006 0.0042 0.0659
Leishmania major aldo-keto reductase-like protein 0.003 0.0518 0.604
Schistosoma mansoni ferritin light chain 0.0005 0.0038 0.0044
Brugia malayi RE15519p 0.0005 0.0024 0.0077
Onchocerca volvulus 0.0004 0.0011 0.0031
Loa Loa (eye worm) hypothetical protein 0.0005 0.0024 0.0077
Entamoeba histolytica endonuclease/exonuclease/phosphatase domain containing protein 0.0006 0.0042 0.0659
Brugia malayi guanine nucleotide-binding protein alpha-7 subunit, putative 0.0004 0.0011 0.0035
Loa Loa (eye worm) hypothetical protein 0.0005 0.0024 0.0077
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0027 0.0474 1
Brugia malayi Guanine nucleotide-binding protein alpha-12 subunit, putative 0.0004 0.0011 0.0035
Loa Loa (eye worm) hypothetical protein 0.0005 0.0024 0.0077
Trichomonas vaginalis aldo/keto reductase, putative 0.003 0.0518 0.1448
Entamoeba histolytica alcohol dehydrogenase, putative 0.0009 0.0102 0.1841
Trichomonas vaginalis conserved hypothetical protein 0.0004 0.0013 0.0015
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0046 0.0853 0.0999
Schistosoma mansoni ferritin light chain 0.0005 0.0038 0.0044
Entamoeba histolytica Flap nuclease, putative 0.0019 0.0305 0.5824
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0005 0.0024 0.0028
Plasmodium vivax hypothetical protein, conserved 0.0006 0.0042 0.0721
Plasmodium falciparum flap endonuclease 1 0.0019 0.0305 0.6374
Loa Loa (eye worm) hypothetical protein 0.0005 0.0024 0.0077
Echinococcus granulosus 7tm_1 domain containing protein 0.0005 0.0024 0.0028
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0019 0.0305 0.3518
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0004 0.0011 0.0009
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0004 0.0009 0.001
Loa Loa (eye worm) flap endonuclease-1 0.0019 0.0305 0.0985
Onchocerca volvulus 0.0004 0.0011 0.0031
Echinococcus multilocularis rhodopsin orphan GPCR 0.0005 0.0024 0.0024
Onchocerca volvulus 0.0005 0.0024 0.0067
Schistosoma mansoni polycystin 1-related 0.0041 0.074 0.0868
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0006 0.0042 0.0133
Plasmodium vivax oxidoreductase, aldo/keto reductase domain containing protein 0.0009 0.0102 0.2015
Echinococcus granulosus ferritin 0.0005 0.0038 0.0044
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0027 0.0474 0.5519
Loa Loa (eye worm) hypothetical protein 0.0005 0.0024 0.0077
Schistosoma mansoni steroid hormone receptor ad4bp 0.0007 0.0077 0.009
Echinococcus granulosus rhodopsin orphan GPCR 0.0005 0.0024 0.0028
Schistosoma mansoni hypothetical protein 0.0005 0.0024 0.0028
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0006 0.0042 0.0659
Leishmania major aldo/keto reductase, putative,aldo/keto reductase family-like protein 0.0009 0.0102 0.1112
Loa Loa (eye worm) hypothetical protein 0.0007 0.0077 0.0247
Schistosoma mansoni thyroid hormone receptor 0.0007 0.0077 0.009
Onchocerca volvulus 0.0005 0.0024 0.0067
Giardia lamblia Inositol 5-phosphatase 4 0.0006 0.0042 0.0659
Brugia malayi larval opioid receptor 0.0005 0.0024 0.0077
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0006 0.0042 0.0133
Schistosoma mansoni neuropeptide receptor 0.0005 0.0024 0.0028
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0004 0.0011 0.0009
Loa Loa (eye worm) hypothetical protein 0.0005 0.0024 0.0077
Schistosoma mansoni synaptojanin 0.0006 0.0042 0.0049
Trichomonas vaginalis conserved hypothetical protein 0.0004 0.0013 0.0015
Schistosoma mansoni growth hormone secretagogue receptor 0.0005 0.0024 0.0028
Leishmania major hypothetical protein, conserved 0.0006 0.0042 0.0398
Onchocerca volvulus 0.0005 0.0024 0.0067
Brugia malayi photoreceptor-specific nuclear receptor 0.0007 0.0077 0.0247
Loa Loa (eye worm) hypothetical protein 0.0005 0.0024 0.0077
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0005 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0005 0.0024 0.0077
Schistosoma mansoni amine GPCR 0.0005 0.0024 0.0028
Echinococcus multilocularis rhodopsin orphan GPCR 0.0005 0.0024 0.0024
Loa Loa (eye worm) histone methyltransferase 0.0006 0.0059 0.0191
Echinococcus granulosus FTZ F1 alpha 0.0007 0.0077 0.009
Loa Loa (eye worm) hypothetical protein 0.0005 0.0024 0.0077
Trypanosoma cruzi aldo/keto reductase, putative 0.0009 0.0102 0.1841
Toxoplasma gondii aldo-keto reductase 0.0009 0.0102 0.1112
Trichomonas vaginalis ocrl type II inositol 5-phosphatase, putative 0.0006 0.0042 0.0095
Loa Loa (eye worm) heterotrimeric G protein alpha subunit 0.0004 0.0011 0.0035
Loa Loa (eye worm) hypothetical protein 0.0005 0.0024 0.0077
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0007 0.0077 0.009
Brugia malayi Flap endonuclease-1 0.0019 0.0305 0.0985
Trichomonas vaginalis ap endonuclease, putative 0.0027 0.0474 0.1323
Loa Loa (eye worm) hypothetical protein 0.0005 0.0024 0.0077
Mycobacterium leprae PROBABLE OXIDOREDUCTASE 0.003 0.0518 1
Echinococcus granulosus hypothetical protein 0.003 0.0518 0.0607
Echinococcus multilocularis neuropeptide FF receptor 2 0.0005 0.0024 0.0024
Brugia malayi steroid hormone receptor 0.0007 0.0077 0.0247
Loa Loa (eye worm) hypothetical protein 0.0004 0.0009 0.0026
Brugia malayi GnHR receptor homolog 0.0005 0.0024 0.0077
Trichomonas vaginalis conserved hypothetical protein 0.0004 0.0013 0.0015
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.003 0.0518 0.1448
Echinococcus granulosus neuropeptide receptor A26 0.0005 0.0024 0.0028
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0007 0.0077 0.0247
Toxoplasma gondii exonuclease III APE 0.0027 0.0474 0.5519
Onchocerca volvulus 0.003 0.0518 0.1466
Echinococcus granulosus biogenic amine 5HT receptor 0.0005 0.0024 0.0028
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.003 0.0518 0.1673
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0027 0.0474 0.9137
Echinococcus multilocularis synaptojanin 1 0.0006 0.0042 0.0041
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0007 0.0077 0.0247
Trypanosoma cruzi Inositol phosphosphingolipids phospholipase C 0.0006 0.0042 0.0659
Onchocerca volvulus 0.0005 0.0024 0.0067
Schistosoma mansoni aldo-keto reductase 0.003 0.0518 0.0608
Schistosoma mansoni cript-related 0.0006 0.0042 0.0049
Loa Loa (eye worm) TYRA-2 protein 0.0005 0.0024 0.0077
Echinococcus multilocularis CCR4 NOT transcription complex subunit 6 0.0006 0.0042 0.0041
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0004 0.0013 0.0015
Loa Loa (eye worm) oxidoreductase 0.003 0.0518 0.1673
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0006 0.0042 0.0095
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0005 0.0024 0.0024
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0005 0.0024 0.0028
Loa Loa (eye worm) hypothetical protein 0.0007 0.0077 0.0247
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.003 0.0518 0.1673
Schistosoma mansoni nuclear hormone receptor 0.0007 0.0077 0.009
Echinococcus granulosus aldehyde reductase 0.0021 0.0349 0.0408
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0023 0.0393 0.046
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0005 0.0038 0.0044
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0005 0.0024 0.0077
Echinococcus granulosus aldo keto reductase 0.003 0.0518 0.0607
Brugia malayi CCR4 0.0006 0.0042 0.0133
Echinococcus multilocularis rhodopsin orphan GPCR 0.0005 0.0024 0.0024
Echinococcus multilocularis g protein coupled receptor 0.0005 0.0024 0.0024
Brugia malayi hypothetical protein 0.0005 0.0024 0.0077
Trichomonas vaginalis conserved hypothetical protein 0.0004 0.0013 0.0015
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0007 0.0077 0.009
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0007 0.0077 0.0247
Brugia malayi Dopamine receptor protein 1 0.0005 0.0024 0.0077
Trichomonas vaginalis aldo-keto reductase, putative 0.003 0.0518 0.1448
Echinococcus granulosus inositol polyphosphate 5 phosphatase OCRL 1 0.0006 0.0042 0.0048
Loa Loa (eye worm) hypothetical protein 0.0005 0.0024 0.0077
Onchocerca volvulus Protein ultraspiracle homolog 0.0007 0.0077 0.0217
Loa Loa (eye worm) hypothetical protein 0.0005 0.0024 0.0077
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0023 0.0393 0.046
Schistosoma mansoni neuropeptide receptor 0.0005 0.0024 0.0028
Echinococcus granulosus aldo keto reductase family 1 member B4 0.003 0.0518 0.0607
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.0004 0.0011 0.0035
Brugia malayi hypothetical protein 0.0005 0.0024 0.0077
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0019 0.0305 0.5824
Loa Loa (eye worm) hypothetical protein 0.0005 0.0024 0.0077
Trichomonas vaginalis GTP-binding protein (O) alpha subunit, gnao, putative 0.0004 0.0011 0.0009
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0007 0.0077 0.009
Trichomonas vaginalis helicase, putative 0.0004 0.0013 0.0015
Loa Loa (eye worm) G protein alpha subunit 3 0.0004 0.0011 0.0035
Mycobacterium ulcerans aldehyde dehydrogenase 0.0046 0.0853 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0007 0.0077 0.0247
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0007 0.0077 0.0247
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0004 0.0009 0.0026
Echinococcus granulosus neuropeptide FF receptor 2 0.0005 0.0024 0.0028
Onchocerca volvulus 0.0005 0.0024 0.0067
Echinococcus granulosus histone lysine methyltransferase setb 0.0023 0.0393 0.046
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.003 0.0518 0.1448
Echinococcus multilocularis neuropeptide s receptor 0.0005 0.0024 0.0024
Schistosoma mansoni biogenic amine (5HT) receptor 0.0005 0.0024 0.0028
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0093 0.1774 0.1774
Echinococcus granulosus alpha 1A adrenergic receptor 0.0005 0.0024 0.0028
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0007 0.0077 0.0247
Schistosoma mansoni ferritin 0.0005 0.0038 0.0044
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0023 0.0393 0.046
Echinococcus multilocularis thyroid hormone receptor alpha 0.0007 0.0077 0.0077
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0005 0.0024 0.0077
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0007 0.0077 0.0077
Echinococcus granulosus g-protein coupled receptor 0.0005 0.0024 0.0028
Echinococcus multilocularis aldo keto reductase 0.003 0.0518 0.0518
Echinococcus granulosus dro:myosuppressin receptor 0.0005 0.0024 0.0028
Loa Loa (eye worm) hypothetical protein 0.0005 0.0024 0.0077
Entamoeba histolytica inositol polyphosphate-5-phosphatase, putative 0.0006 0.0042 0.0659
Schistosoma mansoni synaptojanin 0.0006 0.0042 0.0049
Brugia malayi AKH receptor 0.0005 0.0024 0.0077
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0006 0.0042 0.0398
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0007 0.0077 0.0247
Plasmodium vivax aldehyde reductase, putative 0.0009 0.0102 0.2015
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0019 0.0305 0.5824
Brugia malayi XPG I-region family protein 0.0004 0.0008 0.0024
Echinococcus granulosus rhodopsin orphan GPCR 0.0005 0.0024 0.0028
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0006 0.0042 0.0659
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0004 0.0011 0.0013
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0005 0.0024 0.0028
Trichomonas vaginalis Phospholipase C precursor, putative 0.0006 0.0042 0.0095
Echinococcus granulosus aldo keto reductase family 1 member B4 0.003 0.0518 0.0607
Schistosoma mansoni hypothetical protein 0.0006 0.0042 0.0049
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0027 0.0474 0.0556
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0006 0.0042 0.0659
Brugia malayi Pre-SET motif family protein 0.016 0.3097 1
Schistosoma mansoni biogenic amine (5HT) receptor 0.0005 0.0024 0.0028
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.0004 0.0011 0.0013
Loa Loa (eye worm) hypothetical protein 0.0005 0.0024 0.0077
Echinococcus granulosus rhodopsin orphan GPCR 0.0005 0.0024 0.0028
Brugia malayi follicle stimulating hormone receptor 0.0005 0.0024 0.0077
Loa Loa (eye worm) hypothetical protein 0.0005 0.0024 0.0077
Brugia malayi sulfakinin receptor protein 0.0005 0.0024 0.0077
Leishmania major inositol phosphosphingolipid phospholipase C-Like 0.0006 0.0042 0.0398
Echinococcus multilocularis neutral sphingomyelinase 0.0006 0.0042 0.0041
Echinococcus multilocularis ecdysone induced protein 78C 0.0007 0.0077 0.0077
Plasmodium falciparum DNase I-like protein, putative 0.0006 0.0042 0.0721
Schistosoma mansoni trimeric G-protein alpha o subunit 0.0004 0.0011 0.0013
Schistosoma mansoni neuropeptide F-like receptor 0.0005 0.0024 0.0028
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0005 0.0024 0.0028
Echinococcus granulosus flap endonuclease GEN 1 0.0004 0.0008 0.0009
Schistosoma mansoni cpg binding protein 0.0019 0.031 0.0364
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0006 0.0042 0.0133
Brugia malayi hypothetical protein 0.0005 0.0024 0.0077
Onchocerca volvulus 0.0005 0.0024 0.0067

Activities

Activity type Activity value Assay description Source Reference
k obs / 1 (binding) > 250000 M-1 s-1 Inhibition of human leukocyte elastase(HLE) at 0.7-1.7 microM. ChEMBL. 7853347
k obs / 1 (binding) > 250000 M-1 s-1 Inhibition of human leukocyte elastase(HLE) at 0.7-1.7 microM. ChEMBL. 7853347

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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